6,943 results match your criteria Scoliosis Idiopathic


Prediction of brace effect in scoliotic patients: blinded evaluation of a novel brace simulator-an observational cross-sectional study.

Eur Spine J 2019 Mar 16. Epub 2019 Mar 16.

Anatoscope-Cap-Omega Rond-Point Benjamin Franklin, 34960, Montpellier, France.

Purpose: Bracing is the most commonly used treatment for scoliosis. But braces remain predominantly "handcrafted." Our objective was to create a novel brace simulator using a high-fidelity 3D "avatar" of the patient's trunk. Read More

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http://dx.doi.org/10.1007/s00586-019-05948-9DOI Listing

Preoperative assessment of idiopathic scoliosis in adolescent and young adult with three-dimensional T2-weighted spin-echo MRI.

Diagn Interv Imaging 2019 Mar 13. Epub 2019 Mar 13.

Lille Catholic Hospitals, Imaging Department, 59000 Lille, France; Lille Catholic University, 59000 Lille, France; PMOI Physiopathology of Inflammatory Bone Diseases, EA 4490, 59000 Lille, France. Electronic address:

Purpose: To compare tridimensional (3D) T2-weighted spin-echo MRI and CT for minimal pedicle width measurements in the preoperative assessment of adolescent idiopathic scoliosis (AIS) in adolescent and young patients.

Materials And Methods: A total of 22 adolescents/young patients suffering from AIS were retrospectively included. There were 18 females and 4 males with a mean age of 15. Read More

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http://dx.doi.org/10.1016/j.diii.2019.01.010DOI Listing

Minimal invasive posterior correction of Lenke 5C idiopathic scoliosis: comparative analysis of minimal invasive vs. open surgery.

Arch Orthop Trauma Surg 2019 Mar 14. Epub 2019 Mar 14.

Department of Orthopedics and Traumatology, Wrocław Medical University, ul. Borowska 213, 50-556, Wrocław, Poland.

Introduction: Surgical management of adolescent idiopathic scoliosis in spite of usually favourable outcomes is still a major operation. Therefore, efforts are being undertaken to minimalize the procedure, reduce the surgical trauma and postoperative convalescence. The study was designed to compare posterior minimal invasive surgery using navigation based on intraoperative 3D imaging and standard open instrumented fusion in Lenke 5C idiopathic scoliosis treatment. Read More

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http://dx.doi.org/10.1007/s00402-019-03166-yDOI Listing

Brace treatment in adolescent idiopathic scoliosis patients with curve more than 40 degrees: effectiveness and related factors.

World Neurosurg 2019 Mar 11. Epub 2019 Mar 11.

Department of Spine Surgery, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China. Electronic address:

Objective: The aim of this study was to investigate the effectiveness of brace treatment in adolescent idiopathic scoliosis (AIS) patients with curve between 40 and 45 degrees and to further determine the predictive factors associated with bracing outcome.

Methods: 90 patients with curve exceeding 40 degrees were treated by bracing. Factors including Risser sign, age, gender, curve pattern, curve magnitude, and initial curve correction (ICR) were compared between patients with improved curve and those with progressed curve. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.03.008DOI Listing

Acceptance of a propofol and remifentanil infusion dosing algorithm to optimize postoperative emergence and analgesia.

J Clin Monit Comput 2019 Mar 13. Epub 2019 Mar 13.

Department of Anesthesiology, University of Florida, P.O. Box 100524, Gainesville, FL, 32610-0254, USA.

We implemented a pharmacokinetic/pharmacodynamic (PK/PD) based optimization algorithm recommending intraoperative Remifentanil and Propofol infusion rates to minimize time to emergence and maximize the duration of analgesia in a clinical setting. This feasibility study tested the clinical acceptance of the optimization algorithm's recommendations during scoliosis surgical repair for 14 patients. Anesthesiologist accepted 359/394 (91%) of the recommendations given on the basis of the optimization algorithm. Read More

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http://dx.doi.org/10.1007/s10877-019-00295-yDOI Listing

Fully automated radiological analysis of spinal disorders and deformities: a deep learning approach.

Eur Spine J 2019 Mar 12. Epub 2019 Mar 12.

Unit of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Purpose: We present an automated method for extracting anatomical parameters from biplanar radiographs of the spine, which is able to deal with a wide scenario of conditions, including sagittal and coronal deformities, degenerative phenomena as well as images acquired with different fields of view.

Methods: The location of 78 landmarks (end plate centers, hip joint centers, and margins of the S1 end plate) was extracted from three-dimensional reconstructions of 493 spines of patients suffering from various disorders, including adolescent idiopathic scoliosis, adult deformities, and spinal stenosis. A fully convolutional neural network featuring an additional differentiable spatial to numerical (DSNT) layer was trained to predict the location of each landmark. Read More

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http://dx.doi.org/10.1007/s00586-019-05944-zDOI Listing
March 2019
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The creation of a national coalition to target adolescent idiopathic scoliosis: a meeting report.

Adolesc Health Med Ther 2019 22;10:15-19. Epub 2019 Feb 22.

Department of Pediatrics, McMaster University, Hamilton, ON, Canada,

In this report, we document the discussions and recommendations of a national conference designed to create a coalition to tackle adolescent idiopathic scoliosis (AIS) held on June 6 and 7, 2017 in Hamilton, ON, Canada. The goal of the establishment of this coalition is to join the efforts of patients, parents, physicians, researchers and other stakeholders to identify stakeholders' perspectives and to categorize gaps in knowledge and target further AIS research and clinical care priorities. The participants' main priorities included focus on shared decision making regarding clinical and research priorities between the stakeholders on the clinical, research and policy sides with patients and families. Read More

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http://dx.doi.org/10.2147/AHMT.S199489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390871PMC
February 2019

Investigating the role of IRX family in the development of female AIS: which one is the real cause?

World Neurosurg 2019 Mar 9. Epub 2019 Mar 9.

Department of Spine Surgery, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China. Electronic address:

Background: Previous studies showed that several variants located around the IRX family may have functional roles in the development of AIS. However, there was lack of knowledge concerning the target gene of the region on 5p13.3 and the role of IRX genes in the etiology of AIS. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.02.184DOI Listing

Comparison of the accuracy of cannulated pedicle screw versus conventional pedicle screw in the treatment of adolescent idiopathic scoliosis: A randomized retrospective study.

Authors:
Sinan Yilar

Medicine (Baltimore) 2019 Mar;98(10):e14811

Background: Pedicle screws are commonly used to treat adolescent idiopathic scoliosis (AIS). Many studies have discussed the rates and effects of pedicle screw misplacement. In this study, to increase the accuracy rate, cannulated pedicle screws were inserted into the periapical vertebrae, highly rotated vertebrae, and vertebrae with very thin pedicles in a single patient group. Read More

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http://dx.doi.org/10.1097/MD.0000000000014811DOI Listing

Customized k-nearest neighbourhood analysis in the management of adolescent idiopathic scoliosis using 3D markerless asymmetry analysis.

Comput Methods Biomech Biomed Engin 2019 Mar 8:1-10. Epub 2019 Mar 8.

a Department of Civil and Environmental Engineering , University of Alberta , Edmonton , Canada.

Adolescent Idiopathic Scoliosis (AIS) is a 3D spinal deformity characterized by curvature and rotation of the spine. Markerless surface topography (ST) analysis has been proposed for diagnosing and monitoring AIS to reduce the X-ray radiation exposure to patients. This method captures scans of the cosmetic deformity of the torso using visible, radiation-free light. Read More

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http://dx.doi.org/10.1080/10255842.2019.1584795DOI Listing

Predicting lowest hemoglobin level and risk of blood transfusion in spinal fusion surgery for adolescent idiopathic scoliosis.

Eur Spine J 2019 Mar 8. Epub 2019 Mar 8.

University of Montreal, Montreal, Canada.

Purpose: The aim of this study was to evaluate the factors associated with timing of lowest hemoglobin (Hb) level and the need for postoperative blood transfusion in posterior spinal fusion for adolescent idiopathic scoliosis.

Methods: We conducted a retrospective review of all adolescent scoliosis patients undergoing posterior spinal fusion at our institution, 2002-2014. Surgery consisted of segmental pedicle screw fixation using multi-level pedicle screws. Read More

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http://dx.doi.org/10.1007/s00586-019-05939-wDOI Listing

Efficacy of the Game Ready cooling device on postoperative analgesia after scoliosis surgery in children.

Eur Spine J 2019 Jan 31. Epub 2019 Jan 31.

Department of Anaesthesia, Intensive Care and Pain Management, Robert Debré University Hospital, Paris Diderot University, Paris Sorbonne Cité, 48 Bd Sérurier, 75019, Paris, France.

Purpose: The aim of this study was to investigate the opioid-sparing effect of a cooling brace after surgical correction of idiopathic surgery in children.

Methods: We compared two consecutive cohorts of patients before and after introducing this technique in our institution. Management of patients was standardized. Read More

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http://dx.doi.org/10.1007/s00586-019-05886-6DOI Listing
January 2019
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Adolescent idiopathic scoliosis associated POC5 mutation impairs cell cycle, cilia length and centrosome protein interactions.

PLoS One 2019 7;14(3):e0213269. Epub 2019 Mar 7.

Faculty of Dentistry, Université de Montréal, Montréal, Québec, Canada.

Adolescent Idiopathic Scoliosis (AIS) is a spinal deformity that affects approximately 3 percent of human adolescents. Although the etiology and molecular basis of AIS is unclear, several genes such as POC5 have been identified as possible causes of the condition. In order to understand the role of POC5 in the pathogenesis of AIS, we investigated the subcellular localization of POC5 in cilia of cells over-expressing either the wild type (wt) or an AIS-related POC5 variant POC5A429V. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213269PLOS
March 2019
1 Read

Editor's Spotlight/Take 5: How Common Is Back Pain and What Biopsychosocial Factors Are Associated With Back Pain in Patients With Adolescent Idiopathic Scoliosis?

Authors:
Seth S Leopold

Clin Orthop Relat Res 2019 Mar 4. Epub 2019 Mar 4.

S. S. Leopold, Editor-In-Chief, Clinical Orthopaedics and Related Research®, Philadelphia, PA, USA.

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http://dx.doi.org/10.1097/CORR.0000000000000689DOI Listing
March 2019
1 Read

Health-related quality of life in children and adolescent with different types of scoliosis: A cross-sectional study.

J Chin Med Assoc 2019 Feb;82(2):161-165

Department of Physical Medicine and Rehabilitation, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.

Background: The health-related quality of life (HRQoL) was affected in children and adolescents with scoliosis. However, there was lack of study to compare the HRQoL among patients with different types of scoliosis. We aimed to investigate whether the HRQoL differs among patients with idiopathic, congenital, neuromuscular, and syndromic scoliosis. Read More

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http://dx.doi.org/10.1097/JCMA.0000000000000020DOI Listing
February 2019

Development of a multibody model to assess efforts along the spine for the rehabilitation of adolescents with idiopathic scoliosis.

J Musculoskelet Neuronal Interact 2019 Mar;19(1):4-12

Mechanical engineering department, Polytechnique Montreal, Montreal (QC), Canada.

Introduction: Gait analysis has often been recognized as helpful for the therapeutic follow-up of adolescents with idiopathic scoliosis (IS).

Methods: A multibody model of the human body was developed to display the intervertebral efforts along the spine of each adolescent with IS, and highlight the efforts that significantly differ from typical age-matched healthy adolescents. The intervertebral efforts of one adolescent with IS and an age-matched adolescent during a complete gait cycle were computed and compared. Read More

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March 2019
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2.400 Impact Factor

Theory of Bowstring Disease: Diagnosis and Treatment Bowstring Disease.

Orthop Surg 2019 Feb;11(1):3-9

Department of Orthopedic Surgery, Spine Center, Changzheng Hospital, Second Military Medical University.

Bowstring disease (BSD) is a new classification of spine disease caused by axial stretched lesion on nerve roots and the spinal cord, which is differentiated from disc herniation and canal stenosis in that it is caused by nerve compression lesions. BSD could be caused by mismatched growth rates between the spine and nerve roots (the juvenile type), or by imbalanced degenerative rates between the spine column and nerve roots (degenerative type). Here, we propose that there are several self-adjust mechanisms to relieve axial nerve tension: (i) nerve growth; (ii) posture adjustment and low back pain; (iii) autogenous degeneration of intervertebral disc; and (iv) idiopathic and degenerative scoliosis. Read More

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http://dx.doi.org/10.1111/os.12417DOI Listing
February 2019
1 Read

Effectiveness of scoliosis-specific exercises for adolescent idiopathic scoliosis compared with other non-surgical interventions: a systematic review and meta-analysis.

Physiotherapy 2018 Oct 27. Epub 2018 Oct 27.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Warwick Clinical Trials Unit, University of Warwick, Coventry, UK.

Study Design: Systematic review and meta-analysis.

Objective: To assess the effectiveness of scoliosis-specific exercises (SSE) on adolescent idiopathic scoliosis (AIS) compared with other non-surgical interventions.

Background: AIS is a complex deformity of the spine that develops between the age of 10years and skeletal maturity. Read More

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http://dx.doi.org/10.1016/j.physio.2018.10.004DOI Listing
October 2018

Adiponectin regulates bone mass in AIS osteopenia via RANKL/OPG and IL6 pathway.

J Transl Med 2019 Feb 28;17(1):64. Epub 2019 Feb 28.

Department of Spine Surgery, Xiangya Hospital of Central-South University, Changsha, 410008, Hunan, China.

Background: Osteopenia have been well documented in adolescent idiopathic scoliosis (AIS). Adiponectin has been shown to be inversely proportional to body mass index and to affect bone metabolism. However, the circulating levels of adiponectin and the relationship between adiponectin and low bone mass in AIS remain unclear. Read More

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http://dx.doi.org/10.1186/s12967-019-1805-7DOI Listing
February 2019
1 Read

Health-Related Quality of Life and Postural Changes of Spinal Alignment in Female Adolescents Associated with Back Pain in Adolescent Idiopathic Scoliosis - A Prospective Cross-Sectional Study.

Spine (Phila Pa 1976) 2019 Feb 4. Epub 2019 Feb 4.

Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.

MINI: Poor self-image and mental health as well as large postural changes of apical vertebral translation at main thoracic curve were associated with chronic back pain or back pain at rest in AIS patients. Psychological factors and postural changes of spinal alignment rather than curve severity were associated with back pain.

Study Design: A prospective cross-sectional study. Read More

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http://dx.doi.org/10.1097/BRS.0000000000002996DOI Listing
February 2019
2 Reads

Effectiveness of school scoliosis screening and the importance of this method in measures to reduce morbidity in an Italian territory.

J Pediatr Orthop B 2019 Feb 22. Epub 2019 Feb 22.

U.O.C. of Orthopedics and Traumatology.

Although several procedures for treating scoliosis have been developed, the most effective treatment is still based on early detection. For early diagnosis of idiopathic scoliosis, many authors have proposed methods of school screening; however, there is still no standardized screening program. The aim of this study was to evaluate a school screening method and the prevalence and distribution of scoliosis in Italian school children, aged 9-14 years, and to determine if the screening method can reduce morbidity in an Italian territory. Read More

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http://dx.doi.org/10.1097/BPB.0000000000000611DOI Listing
February 2019

The Sagittal Thoracic Modifier Component of the Lenke Classification System in Moderate and Severe Adolescent Idiopathic Scoliosis: Reliability and Reproducibility of Measurements Among 5 Observers.

Clin Spine Surg 2019 Feb 21. Epub 2019 Feb 21.

Spine Unit, Al-Hadra University Hospital, Alexandria University, Alexandria, Egypt.

Study Design: A prospective radiographic study.

Summary Of Background Data: As the importance of the spinal sagittal profile becomes increasingly evident, there is a need to ensure that the measuring methods used to evaluate thoracic kyphosis (TK) are both accurate and reproducible.

Objective: The purpose of the following study was to determine the intraobserver and interobserver variability of measurements of the sagittal profile in moderate and severe thoracic scoliosis. Read More

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http://dx.doi.org/10.1097/BSD.0000000000000805DOI Listing
February 2019

Distal chromosome 16p11.2 duplications containing in patients with scoliosis.

J Med Genet 2019 Feb 25. Epub 2019 Feb 25.

Department of Neurology, Division of Pediatric Neurology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.

Introduction: Adolescent idiopathic scoliosis (AIS) is a common musculoskeletal disorder with strong evidence for a genetic contribution. CNVs play an important role in congenital scoliosis, but their role in idiopathic scoliosis has been largely unexplored.

Methods: Exome sequence data from 1197 AIS cases and 1664 in-house controls was analysed using coverage data to identify rare CNVs. Read More

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http://jmg.bmj.com/lookup/doi/10.1136/jmedgenet-2018-105877
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http://dx.doi.org/10.1136/jmedgenet-2018-105877DOI Listing
February 2019
3 Reads

Association between perioperative surgical home implementation and transfusion patterns in adolescents with idiopathic scoliosis undergoing spinal fusion.

Paediatr Anaesth 2019 Feb 23. Epub 2019 Feb 23.

Research Center for Genetic Medicine, Children's National Health System, Washington, DC, USA.

Background: Blood transfusions in patients with adolescent idiopathic scoliosis after fusion have been associated with increased morbidity, mortality, and cost.

Objective: The aim of this study was to evaluate the association between implementation of blood-conservation strategies within the perioperative surgical home on transfusion rates for patients with adolescent idiopathic scoliosis undergoing spinal fusion.

Methods: 213 patients (44 pre-perioperative surgical home, 169 post-perioperative surgical home) who underwent posterior spine fusion for adolescent idiopathic scoliosis between June 23, 2014, and July 30, 2017, were enrolled in this case control study. Read More

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http://dx.doi.org/10.1111/pan.13617DOI Listing
February 2019
1.742 Impact Factor

Progressive decline in pulmonary function 5 years post-operatively in patients who underwent anterior instrumentation for surgical correction of adolescent idiopathic scoliosis.

Eur Spine J 2019 Feb 23. Epub 2019 Feb 23.

Rady Children's Hospital, 3020 Children's Way, MC5062, San Diego, CA, 92123, USA.

Purpose: To evaluate changes in pulmonary function tests (PFT) at 5 years post-operatively in patients with adolescent idiopathic scoliosis (AIS) and to determine whether these changes are progressive or static after 2 years.

Methods: AIS surgical patients with pre-operative and 5 year post-operative forced expiratory volume (FEV) and forced vital capacity (FVC) were included. The percentage of patients with pulmonary impairment at 5 years was calculated. Read More

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http://link.springer.com/10.1007/s00586-019-05923-4
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http://dx.doi.org/10.1007/s00586-019-05923-4DOI Listing
February 2019
5 Reads

Management of Adolescent Idiopathic Scoliosis: Institutional Experience, Integration into Neurosurgical Practice, and Impact on Resident Training.

World Neurosurg 2019 Feb 21. Epub 2019 Feb 21.

Department of Neurological Surgery, Loyola University Medical Center, Maywood IL USA. Electronic address:

Objective: Management of adolescent idiopathic scoliosis (AIS) in Neurosurgery residency training may have a significant impact on resident experience, even though few trainees are likely to pursue careers in the field of AIS. The impact of this exposure on resident knowledge in adult spinal disease management is the subject of our retrospective analysis.

Methods: An analysis was performed of all adolescent patients undergoing surgical correction of spinal deformity between 2006 and 2016. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.291DOI Listing
February 2019
1 Read

Deep surgical site infection following thoracolumbar instrumented spinal surgery. Ten years of experience.

Rev Esp Cir Ortop Traumatol 2019 Feb 19. Epub 2019 Feb 19.

Unidad de Raquis, Servicio de Cirugía Ortopédica y Traumatología, Hospital Universitario de Getafe, Getafe, Madrid, España.

Objective: To describe the characteristics and evolution of deep surgical site infection following thoracolumbar instrumented spinal surgery (DSITIS) in our centre over a period of ten years.

Material And Method: Descriptive retrospective study. Patient data (epidemiological/health status), surgical data, infection characteristics/presentation, isolated microorganisms, required surgical debridements, implant removal and major complications linked to infection were evaluated. Read More

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http://dx.doi.org/10.1016/j.recot.2018.11.003DOI Listing
February 2019

A multiethnic meta-analysis defined the association of rs12946942 with severe adolescent idiopathic scoliosis.

J Hum Genet 2019 Feb 21. Epub 2019 Feb 21.

Laboratory of Bone and Joint Diseases, Center for Integrative Medical Sciences, RIKEN, Tokyo, Japan.

Adolescent idiopathic scoliosis (AIS) is the most common type of scoliosis. Controlling its curve progression is the most important clinical task. Although recent genome-wide association studies (GWASs) identified several susceptibility loci associated with the development of AIS, the etiology of curve progression has been still unknown. Read More

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http://dx.doi.org/10.1038/s10038-019-0575-7DOI Listing
February 2019

Can posterior implant removal prevent device-related vertebral osteopenia after posterior fusion in adolescent idiopathic scoliosis? A mean 29-year follow-up study.

Eur Spine J 2019 Feb 19. Epub 2019 Feb 19.

Niigata Bone Science Institute, 761 Kizaki, Kitaku, Niigata City, 950-3304, Niigata, Japan.

Purpose: To determine whether posterior implant removal prevents stress-shielding-induced vertebral osteopenia within the posterior fusion area in surgically treated patients with adolescent idiopathic scoliosis (AIS).

Methods: Eighteen patients with major thoracic AIS (mean age, 43.3 years; range, 32-56 years; mean follow-up, 28. Read More

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http://dx.doi.org/10.1007/s00586-019-05921-6DOI Listing
February 2019

A novel technique for the subfascial insertion of magnetically controlled growing rods - The Alder Hey technique.

J Craniovertebr Junction Spine 2018 Oct-Dec;9(4):250-253

Department of Trauma and Orthopaedics, Alder Hey Children's Hospital, Liverpool, UK.

Purpose: In this study, we would like to describe a novel technique for subfascial insertion of magnetically controlled growing rods using chest drain during surgery for early-onset scoliosis.

Materials And Methods: Posterior approach, surgical dissection to the spine is performed exposing the relevant anatomy to allow placement of pedicle screws always in the distal construct and pedicle screws or hooks in the proximal construct. To allow easy passage of the Magnetic Expansion Control (MAGEC) rod, as well as easy maneuvering of the rod in either the cranial to caudal direction, we use a chest drain of size 24 French diameter as a tunnel. Read More

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http://dx.doi.org/10.4103/jcvjs.JCVJS_105_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364367PMC
February 2019
3 Reads

ROTATION ASSESSMENT IN ADOLESCENT IDIOPATHIC SCOLIOSIS WITH ROD DEROTATION.

Acta Ortop Bras 2019 Jan-Feb;27(1):42-45

Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas (IOT-HCFMUSP), Instituto de Ortopedia e Traumatologia, Spine Surgery Division, São Paulo, SP, Brazil.

Objective: Adolescent idiopathic scoliosis (AIS) is characterized by rotational and lateral deformity of the spine. The measurement of vertebral rotation is important for prognosis and treatment. Our objective was to evaluate whether the Nash-Moe method can be used to measure axial deformity correction with surgical treatment using the rod derotation maneuver at both the apex and extremities of the deformity in patients with AIS. Read More

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http://dx.doi.org/10.1590/1413-785220192701191874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362703PMC
February 2019

COMPARISON OF IMPLANT DENSITY IN THE MANAGEMENT OF LENKE 1B AND 1C ADOLESCENT IDIOPATHIC SCOLIOSIS.

Acta Ortop Bras 2019 Jan-Feb;27(1):33-37

Texas Scottish Rite Hospital for Children, Dallas, TX, USA.

Objective: To compare radiographic and surgical outcomes of Lenke 1B and 1C patterns.

Methods: One hundred twenty patients with Lenke 1B and 1C scoliosis were grouped according to implant density as follows: low density (LD) of ≤1.4 and high density (HD) of >1. Read More

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http://dx.doi.org/10.1590/1413-785220192701189400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362690PMC
February 2019

Hyperchloremia and Diuresis in Children Undergoing Scoliosis Surgery: A Retrospective Cohort Study.

Isr Med Assoc J 2019 Feb;21(2):94-99

Division of Anesthesiology, Critical Care and Pain Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Background: Hyperchloremia is frequent in adult surgical patients and is associated with renal dysfunction. Studies in surgical pediatric patients are lacking.

Objectives: To identify both the incidence of postoperative hyperchloremia in children undergoing surgery for idiopathic and non-idiopathic scoliosis, and the association of postoperative hyperchloremia with intraoperative fluid management and postoperative diuresis. Read More

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February 2019
2 Reads

Increased acute postoperative wound problems following spinal fusion in overweight patients with adolescent idiopathic scoliosis.

J Pediatr Orthop B 2019 Feb 15. Epub 2019 Feb 15.

Shriners Hospital for Children Medical Center.

This study assessed the rate of adverse wound events in individuals with adolescent idiopathic scoliosis who underwent a posterior spinal fusion and sought to determine if obesity was related to the rate of adverse wound events. A retrospective review of patients with adolescent idiopathic scoliosis that underwent posterior spinal fusion between 2001 and 2013 was performed. Preoperative, perioperative, and postoperative data, including wound adverse events, were obtained through medical record review. Read More

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http://dx.doi.org/10.1097/BPB.0000000000000610DOI Listing
February 2019
1 Read

Could the clinical effectiveness be improved under the integration of orthotic intervention and scoliosis specific exercise in managing adolescent idiopathic scoliosis? -A randomized controlled trial study.

Am J Phys Med Rehabil 2019 Feb 13. Epub 2019 Feb 13.

Department of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China.

Objective: To compare the effectiveness of the integration of orthotic intervention (OI) and scoliosis specific exercise (SSE) with orthotic intervention only via assessing the spinal deformity, back muscle endurance and pulmonary function of the patients with adolescent idiopathic scoliosis (AIS).

Design: It is a prospective randomized controlled study. Patients who fulfilled the SRS criteria for OI were randomly assigned to the OE group (combined orthotic and exercise intervention) or the OI group (orthotic intervention only). Read More

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http://dx.doi.org/10.1097/PHM.0000000000001160DOI Listing
February 2019
1 Read
2.012 Impact Factor

Association between lay perception of morbidity and appropriateness of specialized health care use in adolescent idiopathic scoliosis.

J Orthop Res 2019 Feb 12. Epub 2019 Feb 12.

Sainte-Justine University Health Centre, 3175 Ch. Côte-Sainte-Catherine, Montréal, Québec, Canada, H3T 1C5.

In absence of school scoliosis screening programs (SSSP) in Canada, this study examined the relationships between the lay person's perception of morbidity and the appropriateness of referral in orthopedics. A cross-sectional study was conducted with all children consecutively referred in orthopedics for suspected scoliosis. The 831 participants were classified as Appropriate, Late, or Inappropriate referrals for the orthopedic setting. Read More

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http://dx.doi.org/10.1002/jor.24249DOI Listing
February 2019

A New Look at Causal Factors of Idiopathic Scoliosis: Altered Expression of Genes Controlling Chondroitin Sulfate Sulfation and Corresponding Changes in Protein Synthesis in Vertebral Body Growth Plates.

Int J Med Sci 2019 1;16(2):221-230. Epub 2019 Jan 1.

University of Pittsburgh, Pittsburgh PA, USA.

In a previous report, we demonstrated the presence of cells with a neural/glial phenotype on the concave side of the vertebral body growth plate in Idiopathic Scoliosis (IS) and proposed this phenotype alteration as the main etiological factor of IS. In the present study, we utilized the same specimens of vertebral body growth plates removed during surgery for Grade III-IV IS to analyse gene expression. We suggested that phenotype changes observed on the concave side of the vertebral body growth plate can be associated with altered expression of particular genes, which in turn compromise mechanical properties of the concave side. Read More

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http://dx.doi.org/10.7150/ijms.29312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367535PMC
January 2019
1 Read

Etiology of Adolescent Idiopathic Scoliosis: A Literature Review.

Asian Spine J 2019 Feb 13. Epub 2019 Feb 13.

Department of Orthopedic Surgery, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, USA.

Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Read More

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http://dx.doi.org/10.31616/asj.2018.0096DOI Listing
February 2019
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Long-term follow-up after surgical treatment of adolescent idiopathic scoliosis using high-density pedicle screw constructs: Is 5-year routine visit required?

Eur Spine J 2019 Feb 11. Epub 2019 Feb 11.

University of Montreal, Montreal, Canada.

Purpose: The objective of this study is to determine whether routine follow-up 5 years after adolescent idiopathic scoliosis (AIS) surgery is likely to affect postoperative care for patients treated with high-density pedicle screw constructs, when routine 2-year follow-up has been performed.

Methods: We reviewed 80 patients undergoing surgery for AIS using high-density pedicle screw constructs and followed routinely 2 and 5 years after surgery. Quality of life (QOL) was assessed using the SRS-30 outcome questionnaire. Read More

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http://dx.doi.org/10.1007/s00586-019-05887-5DOI Listing
February 2019

Where to stop distally in Lenke modifier C AIS with lumbar curve more than 60°: L3 or L4?

Clin Neurol Neurosurg 2019 Mar 5;178:77-81. Epub 2019 Feb 5.

Spine Surgery, Drum Tower Hospital of Nanjing University Medical School, Zhongshan Road 321, Nanjing, 210008, China. Electronic address:

Objective: Selecting lowest instrumented vertebra (LIV) in adolescent idiopathic scoliosis (AIS) with large lumbar curve can be difficult. Stopping the distal fusion at L3 could save more mobile lumbar segments but may increase the risk of decompensation. This study was designed to evaluate preoperative radiographic factors that were associated with the selection of either L3 or L4 as LIV in posteriorly treated AIS patients with large lumbar curve. Read More

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http://dx.doi.org/10.1016/j.clineuro.2019.02.005DOI Listing

Incidence and Risk Factors of Cardiac Abnormalities in Patients with Idiopathic Scoliosis.

World Neurosurg 2019 Feb 8. Epub 2019 Feb 8.

Department of Musculoskeletal Oncology, Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China. Electronic address:

Objective: We sought to investigate the incidence of cardiac abnormalities in patients with idiopathic scoliosis and identify risk factors related to cardiac abnormalities.

Methods: A cohort of 531 patients with idiopathic scoliosis requiring surgical treatment in our hospital from March 2009 to August 2017 were recorded. Clinical data including medical records, radiograph, and echocardiogram were collected. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.177DOI Listing
February 2019
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Spinal Instrumentation in Growing Children Retards the Natural Development of Pelvic Incidence.

J Pediatr Orthop 2019 Mar;39(3):141-145

Department of Orthopaedics and Traumatology, Hacettepe University School of Medicine, Ankara.

Background: Pelvic incidence increases gradually throughout growth until skeletal maturity. Growing rod instrumentation has been suggested to have a stabilizing effect on the development of the normal sagittal spinal alignment. The purpose of this study is to determine the effect of fixed sagittal plane caused by dual growing rod instrumentation on the natural progression of sagittal spinopelvic parameters in children with idiopathic or idiopathic-like early onset scoliosis. Read More

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http://dx.doi.org/10.1097/BPO.0000000000000882DOI Listing

Non-ionizing method of screening adolescent idiopathic scoliosis in schoolchildren.

Cien Saude Colet 2019 Feb;24(2):523-534

Departamento de Engenharia de Estruturas, Escola de Engenharia, Universidade Federal de Minas Gerais (UFMG). Av. Antônio Carlos 6627, Pampulha. 31270-901 Belo Horizonte MG Brasil.

Adolescent idiopathic scoliosis (AIS) affects 2% to 4% of young people in Brazil. Repeated exposures to radiation used in the monitoring of the deformity can be harmful to the health. This study aimed to present a photogrammetry protocol as a non-ionizing method to quantify scoliosis and relate it to the Cobb radiological method. Read More

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http://dx.doi.org/10.1590/1413-81232018242.12882017DOI Listing
February 2019

Correction to: The "Risser+" grade: a new grading system to classify skeletal maturity in idiopathic scoliosis.

Eur Spine J 2019 Feb 6. Epub 2019 Feb 6.

Boston Children Hospital, Harvard Medical School, Boston, USA.

Unfortunately, the affiliation of the author Negrini S has been incorrectly published in the original version. The complete correct affiliation of this author should read as follows. Read More

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http://dx.doi.org/10.1007/s00586-018-5854-zDOI Listing
February 2019

A prospective analysis of motion and deformity at the shoulder level in surgically treated adolescent idiopathic scoliosis.

Gait Posture 2019 Jan 23;69:150-155. Epub 2019 Jan 23.

Sint Maartenskliniek Research, Sint Maartenskliniek, Hengstdal 3, 6574 NA Ubburgen, the Netherlands.

Background: Although posterior spinal correction and fusion surgery (PSF) of adolescent idiopathic scoliosis (AIS) limits counter rotation between thorax and pelvis, the physical function, and more specifically gait of these patients is only slightly affected after PSF. Possibly, shoulders-thorax counter-rotation increases to compensate for the loss in thorax-pelvis motion. This would subsequently result in a higher phase-difference and range of motion (ROM) between the shoulders and thorax. Read More

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http://dx.doi.org/10.1016/j.gaitpost.2019.01.031DOI Listing
January 2019
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Pedicle stress shielding following growing rod implantation: case report.

J Neurosurg Spine 2019 Feb 1:1-5. Epub 2019 Feb 1.

1Department of Neurosurgery, Shriners Hospitals for Children-Philadelphia, Pennsylvania; and.

Growing rod surgery for skeletally immature patients helps correct severe scoliosis while allowing continued spinal column growth. Previous reports have studied vertebral body changes following growing rod surgery, but there are currently no published reports on alterations in pedicle morphology. Given the potential need for definitive spinal fusion with pedicle screw instrumentation, an awareness of changes in pedicle morphology is critical. Read More

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http://dx.doi.org/10.3171/2018.10.SPINE18955DOI Listing
February 2019
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Editorial on "".

J Spine Surg 2018 Dec;4(4):812-816

Twin Cities Spine Center, Minneapolis, MN, USA.

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http://dx.doi.org/10.21037/jss.2018.10.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330580PMC
December 2018
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Effect of thoracic kyphosis formation and rotational correction by direct vertebral rotation after the simultaneous double rod rotation technique for idiopathic scoliosis.

Clin Neurol Neurosurg 2019 Mar 28;178:56-62. Epub 2019 Jan 28.

Department of Orthopaedic Surgery, Faculty of Medicine, Oita University, Oita, Japan.

Objective: The objective of the present study was to evaluate the effect of thoracic kyphosis formation and rotational correction by direct vertebral rotation (DVR) after the simultaneous double-rod rotation technique (SDRRT) for idiopathic scoliosis (IS).

Patients And Methods: The present study included twelve patients with IS who received SDRRT (SDRRT group) and twelve patients with IS who received DVR after SDRRT (SDRRT + DVR group). We investigated the following parameters preoperatively, postoperatively, and at postoperative 2 years: Cobb angle (PT, MT, T/L, C7-CSVL, AVT, TK (T5-12), LL(L1-S1) RSH, the angle of rotation (RAsag), percent change of RAsag and SRS22 (at postoperative 2 years only). Read More

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http://dx.doi.org/10.1016/j.clineuro.2019.01.014DOI Listing

Effectiveness of posterior structures in the development of proximal junctional kyphosis following posterior instrumentation: A biomechanical study in a sheep spine model.

Acta Orthop Traumatol Turc 2019 Jan 30. Epub 2019 Jan 30.

Istanbul University, Istanbul Faculty of Medicine, Department of Orthopedics and Traumatology, Istanbul, Turkey.

Introduction: Proximal junctional kyphosis - PJK has been defined by a 10 or greater increase in kyphosis at the proximal junction as measured by the Cobb angle from the caudal endplate of the uppermost instrumented vertebrae (UIV) to the cephalad endplate of the vertebrae 1 segments cranial to the UIV. In this biomechanical study, it is aimed to evaluate effects of interspinosus ligament complex distruption and facet joint degeneration on PJK development.

Materials And Methods: Posterior instrumentation applied between T2 - T7 vertebrae using pedicle screws to randomly selected 21 sheeps, divided into 3 groups. Read More

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http://dx.doi.org/10.1016/j.aott.2019.01.003DOI Listing
January 2019
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Anatomical reference marks, evaluation parameters and reproducibility of surface topography for evaluating the adolescent idiopathic scoliosis: a systematic review with meta-analysis.

Gait Posture 2019 Jan 2;69:112-120. Epub 2019 Jan 2.

Physical Education, Physiotherapy and Dance School of Universidade Federal do Rio Grande do Sul (UFRGS), ESEFID/LAPEX/BIOMEC, Rua Felizardo, 750, Porto Alegre, RS, CEP 90690-200, Brazil. Electronic address:

Background: Surface topography is a radiation-free examination that provides relevant information for the evaluation of patients with Adolescent Idiopathic Scoliosis (AIS). However, its usage is not standardized, which restricts the applicability of this instrument.

Research Questions: (a) To identify the anatomical reference markers used on surface topography; (b) to identify the parameters used on surface topography; and (c) to pool correlation and reproducibility results. Read More

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http://dx.doi.org/10.1016/j.gaitpost.2019.01.001DOI Listing
January 2019
1 Read