8,983 results match your criteria Sclerotherapy


Red dichromatic imaging reduces endoscopic treatment time of esophageal varices by increasing bleeding point visibility (with video).

Dig Endosc 2021 May 10. Epub 2021 May 10.

Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.

Background: Red dichromatic imaging (RDI) is a novel image-enhanced endoscopy released in 2020, which increases the visibility of deeper vessels. In this study, we retrospectively investigated whether RDI can shorten treatment times of endoscopic injection sclerotherapy (EIS), and which operational procedure times are affected compared with white light imaging (WLI).

Methods: A total of 155 patients (RDI: 70; WLI: 85) with risky esophageal varices (EV), who were treated with EIS were analyzed. Read More

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Changes in anti-müllerian hormone after ultrasound guided aspiration and ethanol sclerotic therapy of ovarian cyst.

Taiwan J Obstet Gynecol 2021 May;60(3):509-512

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, No 199 Dunhua N Rd, Songshan District, Taipei, 105, Taiwan. Electronic address:

Objective: To evaluate the effect of transvaginal ultrasound-guided aspiration and ethanol sclerotherapy on anti-müllerian hormone (AMH) in patients with ovarian endometriomas.

Setting: Teaching hospital affiliated with Chang Gung University, Taipei.

Material And Methods: We retrospectively reviewed 124 patients, with ovarian endometriomas who underwent transvaginal aspiration and sclerotherapy of endometrioma(s) at a tertiary medical center, Chang Gung Memorial Hospital, Taipei, Taiwan. Read More

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The Extended Center for Vein Restoration Study assessing comparative outcomes for the treatment of chronic venous insufficiency in Medicare and Non-Medicare eligible patients.

J Vasc Surg Venous Lymphat Disord 2021 May 6. Epub 2021 May 6.

Center for Vein Restoration, 7474 Greenway Center Drive, Suite 1000 Greenbelt, MD 20770.

Introduction: We have previously reported that chronic venous insufficiency treatments for Medicare eligible patients achieve similar outcomes as non-Medicare eligible patients. The goal of the current investigation is to assess long-term treatment outcomes and the effect of race in a larger patient cohort.

Methods: From January 2015 to December 2019, we retrospectively reviewed data from 131,268 patients who presented for a lower extremity venous evaluation. Read More

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Red light emitting diode as an adjuvant treatment for epidermal growth factor receptor inhibitors-induced paronychia.

J Dermatolog Treat 2021 May 7:1-16. Epub 2021 May 7.

Division of Dermatology, Department of Medicine, Faculty of Medicine, Skin and Allergy Research Unit, Chulalongkorn University, Bangkok, Thailand.

We evaluated the efficacy and safety of red light LED as an adjuvant treatment for epidermal growth factor receptor inhibitor-induced paronychia. Eight patients were recruited in this randomized, single-blinded controlled trial. They were randomized to receive red-light on one hand or foot 2-3 times/week for 6 weeks while the contralateral side served as controls. Read More

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Improvement in quality of life among Sri Lankan patients with haemorrhoids after invasive treatment: a longitudinal observational study.

BJS Open 2021 Mar;5(2)

Duke-NUS Medical School, Singapore.

Background: Haemorrhoids is a common chronic disease that can significantly impact patients' quality of life. Yet, few studies have evaluated health-related quality of life (HRQoL) of patients with haemorrhoids before and after treatment. This study investigated the HRQoL of patients with haemorrhoids before and after treatment and the change in HRQoL from baseline. Read More

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A Prospective Randomized Controlled Trial Using Propofol or Dexmedetomidine for Conscious Sedation in Pediatric Patients Undergoing Sclerotherapy.

J Pediatr Neurosci 2020 Oct-Dec;15(4):379-385. Epub 2021 Jan 19.

Department of Anaesthesia, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.

Aim: Sodium tetradecyl sulfate (STS) sclerotherapy in pediatric patients is usually undertaken under sedation inside digital subtraction angiography (DSA) suite. These patients are day-care patients and need adequate sedation for small duration. We performed this study to compare propofol and dexmedetomidine as sedative agents in these patients. Read More

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January 2021

Efficacy of Micronized Purified Flavonoid Fraction-Based Venoactive Therapy After Endovenous Mechanochemical Obliteration: Prospective Comparative Study.

Drugs Real World Outcomes 2021 Apr 28. Epub 2021 Apr 28.

Vitebsk State Order of Peoples Friendship Medical University, Vitebsk, Republic of Belarus.

Background: Endovenous interventions and minimally invasive open procedures are effective in the management of varicose veins, but can result in post-operative pain/discomfort.

Objective: The objective of this study was to evaluate the clinical efficacy of micronized purified flavonoid fraction venoactive therapy for postoperative pain, vein-specific symptoms, and quality of life in patients with varicose veins following an endovenous mechanochemical ablation procedure.

Methods: This prospective, observational, single-center study allocated patients into two groups: Group A, micronized purified flavonoid fraction 1000 mg once daily for 30 days; Group B, no venoactive drug prescribed (control). Read More

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Propranolol Followed by a Foam Sclerotherapy for Treatment of Tufted Angioma over Neck: A Novel Therapeutic Approach.

J Cutan Aesthet Surg 2020 Oct-Dec;13(4):335-337

Department of Dermatology, MVP's Dr. Vasantrao Pawar Medical College Hospital and Research Center, Nashik, Maharashtra, India.

Tufted angioma is a rare vascular tumor with cutaneous angiomatous proliferation, commonly localized in the skin and subcutaneous tissues. Most cases are usually acquired in childhood, having protracted course with minimal tendency for spontaneous regression. Various treatment modalities have been described in the literature in the management of tufted angioma with variable response. Read More

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Bleomycin Sclerotherapy in Massive Macrocystic Lymphatic Malformation: Minimal Complications with Maximum Results.

J Cutan Aesthet Surg 2020 Oct-Dec;13(4):319-325

Department of Pediatric Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Introduction: Cystic lymphangioma (CL) is a multiloculated congenital malformation of the lymphatic system occurring in approximately 1 in 6,000-12,000 births, and it mostly presents at birth. The CL is of a variable size and it can be found at any age and in any part of the body. This study was carried out to observe the effect of intralesional aqueous bleomycin on giant CL presenting in adult and pediatric cases. Read More

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Lymphatic malformations adjacent to the airway in neonates: Risk factors for outcome.

J Pediatr Surg 2021 Mar 18. Epub 2021 Mar 18.

Department of Pediatric Surgery, Radboudumc-Amalia Children's Hospital, Nijmegen, Netherlands.

Purpose: To evaluate imaging, treatment, and outcomes in neonates with a lymphatic malformation (LM) adjacent to the airway and to evaluate risk factors that can predict outcome.

Methods: A retrospective case series was conducted of ten patients treated between January 2011 and July 2019. The main outcome measures included airway compromise and clinical response to sclerotherapy ± surgery. Read More

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Efficacy of Sclerotherapy With Polidocanol (Ethoxysclerol) in Primary Aneurysmal Bone Cysts in Children and Adolescents.

J Pediatr Orthop 2021 Apr 23. Epub 2021 Apr 23.

Departments of Orthopaedic Surgery Interventional Radiology, Leiden University Medical Centre, Leiden, The Netherlands.

Background: Aneurysmal bone cysts (ABC) are rare benign osseous lesions that can be locally aggressive. Traditionally, curettage with or without bone grafting is the treatment of choice. Recent data suggest that percutaneous sclerotherapy is a safe alternative to surgery. Read More

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Management of macrocystic lymphatic malformation at uncommon site with aqueous bleomycin sclerotherapy.

Natl J Maxillofac Surg 2020 Jul-Dec;11(2):193-198. Epub 2020 Dec 16.

Department of Pediatric Surgery, SGPGIMS, Lucknow, Uttar Pradesh, India.

Introduction: Lymphangioma are rare vascular malformation that results from maldevelopment of primitive lymphatic sacs. They are most frequently found in the neck and axilla, while intra-abdominal and mediastinal lymphangiomas are uncommon. Atypical site of cystic hygroma in pediatric age group are usually difficult to diagnose clinically but can be diagnosed easily by ultrasound. Read More

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December 2020

Single-dose instillation of povidone iodine for chyluria: A safe and effective therapy.

Urol Ann 2021 Jan-Mar;13(1):36-40. Epub 2021 Jan 19.

Department of Urology, SCB Medical College and Hospital, Cuttack, Odisha, India.

Introduction: Management of chyluria with initial conservative approach and then using endoscopic sclerotherapy is a mainstay approach. However, a wide range of sclerosants are available with differential success rates and complication rates. This study evaluated the safety and efficacy of a single-dose instillation of 1% povidone iodine for the treatment of chyluria. Read More

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January 2021

Sclerotherapy in a rare case of glomuvenous malformation (GVM) with severe skin manifestation.

J Eur Acad Dermatol Venereol 2021 Apr 23. Epub 2021 Apr 23.

University Hospital Muenster, Muenster, Germany.

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Surgical or radiological treatment for varicoceles in subfertile men.

Cochrane Database Syst Rev 2021 04 23;4:CD000479. Epub 2021 Apr 23.

Cochrane Austria, Department for Evidence-based Medicine and Evaluation, Danube University Krems, Krems, Austria.

Background: Varicoceles are associated with male subfertility; however, the mechanisms by which varicoceles affect fertility have yet to be satisfactorily explained. Several treatment options exist, including surgical or radiological treatment, however the safest and most efficient treatment remains unclear.  OBJECTIVES: To evaluate the effectiveness and safety of surgical and radiological treatment of varicoceles on live birth rate, adverse events, pregnancy rate, varicocele recurrence, and quality of life amongst couples where the adult male has a varicocele, and the female partner of childbearing age has no fertility problems. Read More

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Sclerotherapy - A novel modality in the management of oral pyogenic granuloma.

J Indian Soc Periodontol 2021 Mar-Apr;25(2):162-165. Epub 2021 Mar 1.

Department of Oral Medicine and Radiology, Modern Dental College and Research Center, Indore, Madhya Pradesh, India.

Pyogenic granuloma is a commonly occurring inflammatory hyperplasia involving the oral cavity. Surgical resection of the lesion is the mainstay treatment of pyogenic granuloma. However, intraoperative bleeding, postoperative infection, and recurrence chances are more with the surgical technique. Read More

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Prolotherapy for chronic low back pain: a review of literature.

Br Med Bull 2021 Apr 21. Epub 2021 Apr 21.

Department of Trauma and Orthopaedic Surgery, Azienda Ospedaliera Universitaria, San Giovanni di Dio e Ruggi D'Aragona, Via San Leonardo 1, Salerno 84131, Italy.

Introduction: Low back pain is common and imposes major societal burdens for patient suffering and costs. Prolotherapy injections are used for musculoskeletal conditions including tendinopathies, osteoarthritis and low back pain to enhance soft-tissue healing. This review aims to clarify the place of prolotherapy in chronic low back pain (CLBP). Read More

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Diagnosis and management of extrahepatic oesophageal variceal bleed in children in a low resourced setting.

Ghana Med J 2020 Dec;54(4):274-278

Department of Child Health, University of Ghana Medical School, College of Health Sciences, University of Ghana, Accra.

Extrahepatic portal vein obstruction (EHPVO) is a major cause of portal hypertension (PH) in children. Portal vein thrombosis (PVT) is the most common cause accounting for up to 75% of cases in developing countries. Upper gastrointestinal bleeding is the most dreaded and commonest presentation of portal hypertension. Read More

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December 2020

Long term outcomes of transcutaneous non-image guided bleomycin sclerotherapy in orbital/adnexal lymphatic malformations: a protocol-based management in 69 eyes.

Eye (Lond) 2021 Apr 20. Epub 2021 Apr 20.

Ophthalmic Plastic and Facial Aesthetic, Orbit and Ocular Oncology Service, Kode Venkatadri Chowdary Campus, L V Prasad Eye Institute, Vijayawada, Andhra Pradesh, India.

Objectives: To study the efficacy and the long-term outcomes of treating micro and macrocystic orbital and/or adnexal lymphatic malformations (OA-LM) with protocol-based bleomycin sclerotherapy.

Methods: A retrospective interventional study of 69 eyes having OA-LM treated with non-image guided transcutaneous or transconjunctival bleomycin sclerotherapy (1IU/ml aqueous solution) between December 2014 and December 2018. Based on clinical regression, the outcomes were classified as excellent, good, fair and poor. Read More

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A novel treatment of sialocele with sodium tetradecyl sclerotherapy.

Am J Otolaryngol 2021 Apr 7;42(5):103031. Epub 2021 Apr 7.

Division of Otolaryngology-Head and Neck Surgery, George Washington University School of Medicine & Health Sciences, Washington, DC, United States of America. Electronic address:

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Esophageal Variceal Ligation Monotherapy versus Combined Ligation and Sclerotherapy for the Treatment of Esophageal Varices.

Can J Gastroenterol Hepatol 2021 29;2021:8856048. Epub 2021 Mar 29.

Department of Gastroenterology, Lishui Hospital of Zhejiang University, Lishui Municipal Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 32300, Zhejiang Province, China.

Currently, endoscopic variceal ligation (EVL) monotherapy is the standard therapy for managing esophageal variceal hemorrhage. Patients generally need several sessions of endoscopy to achieve optimal variceal ablation, and the varices can recur afterward. Endoscopic injection sclerotherapy (EIS) is an older technique, associated with certain complications. Read More

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Giant splenic cyst with expectant management in pregnancy: A case report and review of the literature.

Case Rep Womens Health 2021 Apr 9;30:e00305. Epub 2021 Mar 9.

Department of Surgical Sciences, Città della Salute e della Scienza, Sant'Anna Hospital, Turin, Italy.

A 22-year-old primigravida was diagnosed with an 18-cm splenic cyst during routine third-trimester routine ultrasound examination. She was referred to a tertiary obstetric hospital and after multidisciplinary consultation, expectant management was decided on. Induction of labour was performed at term and she delivered vaginally with vacuum extractor application without complications. Read More

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Evaluation of the efficacy of foam sclerosant after addition of glycerine on human great saphenous vein: histological and immunohistochemical study.

Ann R Coll Surg Engl 2021 Apr 14. Epub 2021 Apr 14.

Alexandria University, Egypt.

Introduction: Several treatment modalities have been postulated to improve the efficacy of varicose vein treatment. Addition of glycerine to the sclerosing material has been documented to increase its viscosity and subsequently prolong the duration of stability, in addition to the direct sclerosing effect of glycerine. This histological and immunohistochemical study investigated the efficacy of addition of glycerine 72% to sclerotherapy on the human varicose vein. Read More

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Outcomes of Saphenous Vein Intervention in the Management of Superficial Venous Incompetence: A Systematic Review and Network Meta-Analysis.

Ann Surg 2021 Apr 9. Epub 2021 Apr 9.

University of Limerick, Limerick, Ireland Department of Vascular Surgery, University Hospital Galway, Ireland Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland Lambe Institute for Translational Discipline of Surgery, National University of Ireland, Galway, Ireland School of Mathematical Sciences, University College Cork, Cork, Ireland Department of Vascular Surgery, Singapore General Hospital, Singapore Duke NUS Graduate Medical School, Singapore.

Objective: To determine the most effective modality of intervention to treat saphenous vein insufficiency.

Summary Background Data: Endovenous therapies have instigated a paradigm shift in the management of superficial venous incompetence (SVI). When compared with open surgery, endovenous interventions (foam sclerotherapy (FS), radiofrequency ablation (RFA), endovenous laser ablation (EVLA), mechanochemical ablation (MOCA), and cyanoacrylate glue (CAE) closure) potentially offer reduced morbidity with similar procedural efficacy. Read More

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Treatment for bleeding oesophageal varices in people with decompensated liver cirrhosis: a network meta-analysis.

Cochrane Database Syst Rev 2021 04 10;4:CD013155. Epub 2021 Apr 10.

Division of Surgery and Interventional Science, University College London, London, UK.

Background: Approximately 40% to 95% of people with liver cirrhosis have oesophageal varices. About 15% to 20% of oesophageal varices bleed within about one to three years after diagnosis. Several different treatments are available, including, among others, endoscopic sclerotherapy, variceal band ligation, somatostatin analogues, vasopressin analogues, and balloon tamponade. Read More

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Bleomycin sclerotherapy following doxycycline lavage in the treatment of ranulas: A retrospective analysis and review of the literature.

Neuroradiol J 2021 Apr 8:19714009211008790. Epub 2021 Apr 8.

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, USA.

Objective: A ranula is a mucus-filled salivary pseudocyst that forms in the floor of the mouth, commonly arising from the sublingual or submandibular salivary glands following obstruction or trauma. Complete excision of the injured gland and removal of the cyst content is the first-choice therapy, but has the potential for complications related to injury to nearby structures. As such, minimally invasive approaches such as percutaneous sclerotherapy have been investigated. Read More

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[Combined use of minimally invasive methods in treatment of varicose veins in an elderly woman].

Angiol Sosud Khir 2021 ;27(1):75-81

Medical Centre of Phlebology and Lymphology "ARD-CLINIC", Krasnodar, Russia.

The authors describe herein a clinical case report regarding a 70-year-old woman presenting with lower-limb varicosity in the system of the great and small saphenous veins, aneurysmal dilatation of the proximal portion of the great saphenous vein, and an open trophic ulcer of the crus with concomitant hypertension and coronary artery disease. Given these factors, she was subjected to endovenous laser coagulation of the great and small saphenous veins, microfoam echosclerotherapy of the distal portion of the trunk of the great saphenous vein and an incompetent perforating vein of the crus, followed by complete obliteration thereof. On POD 7, she developed positive dynamics in the process of healing of the trophic ulcer, and on POD 50 the ulcer healed completely. Read More

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Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network meta-analysis.

Cochrane Database Syst Rev 2021 04 6;4:CD013121. Epub 2021 Apr 6.

Division of Surgery and Interventional Science, University College London, London, UK.

Background: Approximately 40% to 95% of people with cirrhosis have oesophageal varices. About 15% to 20% of oesophageal varices bleed in about one to three years. There are several different treatments to prevent bleeding, including: beta-blockers, endoscopic sclerotherapy, and variceal band ligation. Read More

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Contrast-enhanced ultrasound evaluation of a refractory ovarian endometrial cyst and ultrasound-guided aspiration sclerotherapy using urokinase and lauromacrogol.

Clin Hemorheol Microcirc 2021 Apr 1. Epub 2021 Apr 1.

Department of Medical Ultrasound, Shanghai Tenth People's Hospital; Ultrasound Research and Education Institute, Clinical Research Center for Interventional Medicine, Tongji University School of Medicine; Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment. Shanghai, China.

Endometriosis is one of the most common diseases that happen in reproductive women. The main symptoms include ovarian endometrial cyst, pelvic pain, and so on. We report a case of a 23-year-old woman with a refractory long-course ovarian endometrial cyst (OEC). Read More

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Adjuvant radiofrequency thermocoagulation improves the outcome of liquid sclerotherapy in the treatment of spider veins of the leg: A pilot study.

Phlebology 2021 Apr 4:2683555211006534. Epub 2021 Apr 4.

Cardiovascular Surgery, Ministry of Health Ankara City Hospital, Ankara, Turkey.

Objective: This study evaluated the effect of low-energy radiofrequency thermocoagulation added to standard liquid sclerotherapy on clinical outcomes of patients with venous insufficiency.

Patients And Method: We included 111 patients with spider veins CEAP/C1 stage. The patients were randomized into sclerotherapy (Group 1) and sclerotherapy + sclerotherapy immediately followed by low energy percutaneous RF thermocoagulation (Group 2) groups and followed up with same protocols prospectively. Read More

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