2,041 results match your criteria Scleritis


[Anterior necrotizing scleritis secondary to cytomegalovirus infection: A case report].

J Fr Ophtalmol 2020 Jun 26. Epub 2020 Jun 26.

Service d'ophtalmologie, hôpital Omar-Drissi, CHU de Hassan II Fès, Maroc.

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http://dx.doi.org/10.1016/j.jfo.2019.11.013DOI Listing

Presumed tuberculous sclerokeratouveitis in immunocompetent South African patients.

Eye (Lond) 2020 Jun 25. Epub 2020 Jun 25.

Division of Ophthalmology, Faculty of Medicine and Health Sciences, Stellenbosch University, P.O. Box 241, Cape Town, 8000, South Africa.

Background/objectives: Ocular tuberculosis remains a diagnostic challenge since its clinical presentation is so variable. We describe the clinical characteristics of patients presenting with sclerokeratouveitis secondary to presumed Mycobacterium tuberculosis infection.

Method: Retrospective analysis of 14 patients presenting with sclerokeratouveitis to Tygerberg Hospital. Read More

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http://dx.doi.org/10.1038/s41433-020-1046-2DOI Listing

Evolving consensus for immunomodulatory therapy in non-infectious uveitis during the COVID-19 pandemic.

Br J Ophthalmol 2020 Jun 25. Epub 2020 Jun 25.

Department of Medical Retina and Uveitis, Moorfields Eye Hospital, NHS Foundation Trust, London, United Kingdom.

Background: Immunomodulatory therapy (IMT) is often considered for systemic treatment of non-infectious uveitis (NIU). During the evolving coronavirus disease-2019 (COVID-19) pandemic, given the concerns related to IMT and the increased risk of infections, an urgent need for guidance on the management of IMT in patients with uveitis has emerged.

Methods: A cross-sectional survey of international uveitis experts was conducted. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2020-316776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313529PMC

More Than Meets the Eye: A Rare Case of Posterior Scleritis Masquerading as Orbital Cellulitis.

Cureus 2020 May 18;12(5):e8177. Epub 2020 May 18.

Ophthalmology, Bristol Eye Hospital, Bristol, GBR.

Posterior scleritis is a rare sight-threatening condition that typically presents with an acutely painful eye, often with associated reduced visual acuity. Diagnosis can be challenging and requires specialist ophthalmological assessment. Consequences of delayed treatment include permanent loss of vision. Read More

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http://dx.doi.org/10.7759/cureus.8177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301425PMC

A case report of fulminant endophthalmitis caused by Streptococcus dysgalactiae in a patient with traumatic corneal laceration.

BMC Ophthalmol 2020 Jun 18;20(1):238. Epub 2020 Jun 18.

Department of Cornea and Refractive Surgery, Kim's Eye Hospital, 136, Yeongshin-ro, Yeongdeungpo-gu, Seoul, South Korea.

Background: To report a case of enucleation caused by Streptococcus dysgalactiae endophthalmitis after traumatic corneal laceration.

Case Presentation: A 69-year-old man with history of retinal detachment treated with vitrectomy and subsequent cataract surgery presented with traumatic corneal laceration while cutting grass. Appropriate repair of corneal laceration and intravitreal antibiotics (vancomycin, ceftazidime) injection was performed. Read More

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http://dx.doi.org/10.1186/s12886-020-01511-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301497PMC

Yellow Sub-Retinal Pigment Epithelium (YSRPE) Deposits: A Novel Sign in Ocular Tuberculosis.

Retin Cases Brief Rep 2020 Jun 8. Epub 2020 Jun 8.

Advanced Eye Center, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Purpose: To describe a novel clinical and imaging finding in patients with tubercular posterior uveitis.

Methods: A retrospective review of 3 cases presented at a tertiary referral eye centre in North India between June 2016 to March 2019 was performed. All the patients had received an initial diagnosis of non-infective etiologies (sympathetic ophthalmia, necrotizing scleritis and lymphoma). Read More

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http://dx.doi.org/10.1097/ICB.0000000000001016DOI Listing

Fibromyalgia Syndrome and Eye - a review.

Surv Ophthalmol 2020 Jun 5. Epub 2020 Jun 5.

University of Wrocław, Clinic of Ophthalmology, ul. Borowska 213, 50-556 Wrocław, Poland. Electronic address:

Fibromyalgia is a chronic, widespread pain syndrome, with unclear etiology, characterized by fatigue, sleeping problems, cognitive disorders, somatic complaints and severe pain in tender points of the body at the time of physical activity with no laboratory findings to the disease and diagnostic tests. Fibromyalgia can be associated with ocular symptoms (foreign body sensation, irritation) and visual disturbances (blurred vision), coexisting with dry eye syndrome (DES) and reduced corneal sensitivity. Cases of scleritis, including the necrotizing form, accompanying fibromyalgia have been reported. Read More

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http://dx.doi.org/10.1016/j.survophthal.2020.05.006DOI Listing

Current insights in the pathogenesis of scleritis.

Exp Eye Res 2020 Jun 3:108078. Epub 2020 Jun 3.

Immunology, Laboratory Medical Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.

Scleritis is a sight-threatening inflammation characterized by severe pain and redness of the eye. It can cause blindness by severe complications like scleral and corneal necrosis, keratitis, and uveitis. The pat. Read More

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http://dx.doi.org/10.1016/j.exer.2020.108078DOI Listing

Biologic therapy in severe and refractory peripheral ulcerative keratitis (PUK). Multicenter study of 34 patients.

Semin Arthritis Rheum 2020 May 15;50(4):608-615. Epub 2020 May 15.

Rheumatology, Ophthalmology and Internal medicine, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain. Electronic address:

Purpose: We assessed the efficacy and safety of biologic therapy in severe and refractory Peripheral Ulcerative Keratitis (PUK).

Design: Open-label multicenter study of biologic-treated patients with severe PUK refractory to conventional immunosuppressive drugs.

Subjects: We studied 34 patients (44 affected eyes) (24 women/10 men; mean age, 55. Read More

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http://dx.doi.org/10.1016/j.semarthrit.2020.03.023DOI Listing

Cataract Surgery in the Setting of Scleritis.

Ocul Immunol Inflamm 2020 May 28:1-4. Epub 2020 May 28.

Department of Uvea Medical and Vision Research Foundations, Sankara Nethralaya , Chennai, India.

Purpose: To report the clinical profile of cataract and its surgical management in a scleritis cohort from India.

Methods: We conducted a retrospective review of medical records of 39 eyes of 32 consecutive patients with scleritis who underwent cataract surgery in a tertiary eye care institute.

Results: The mean age at presentation was 50. Read More

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http://dx.doi.org/10.1080/09273948.2020.1754434DOI Listing

Tubulointerstitial Nephritis and Uveitis Syndrome: Characterization of Clinical Features.

Ocul Immunol Inflamm 2020 May 28:1-6. Epub 2020 May 28.

Department of Ophthalmology, Northwestern University Feinberg School of Medicine , Chicago, Illinois, USA.

Purpose: To describe clinical manifestations of patients with tubulointerstitial nephritis and uveitis syndrome (TINU) with a focus on posterior segment findings.

Methods: Retrospective chart review.

Results: 17 patients were diagnosed with TINU. Read More

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http://dx.doi.org/10.1080/09273948.2020.1736311DOI Listing

IDIOPATHIC PENETRATION OF CILIA INTO THE POSTERIOR SEGMENT PRESENTING AS SECTORAL SCLERITIS WITH PROGRESSIVE INTRAOCULAR INFLAMMATION.

Retin Cases Brief Rep 2020 May 25. Epub 2020 May 25.

Department of Ophthalmology, University of Washington, Seattle, Washington.

Purpose: To report two cases of idiopathic intraocular cilia presenting as sectoral scleritis with progressive intraocular inflammation.

Methods: Both patients were treated with intravitreal antibiotics and underwent pars plana vitrectomy where the cilia were removed and identified on histopathology.

Results: One patient developed a retinal detachment while being treated for presumed endophthalmitis. Read More

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http://dx.doi.org/10.1097/ICB.0000000000001006DOI Listing

Bilateral Necrotizing Scleritis: A Deeper Look at a Vision-Threatening Illness.

J Clin Rheumatol 2020 Jun;26(4):e75-e76

From the Department of Medicine, University of Toronto.

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http://dx.doi.org/10.1097/RHU.0000000000000858DOI Listing

[Clinical observation of ocular injury caused by chestnut burr].

Zhonghua Yan Ke Za Zhi 2020 May;56(5):370-375

Qingdao Eye Hospital, State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong First Medical University & Shandong Academy of Medical Sciences, Qingdao 266071, China.

To analyze the clinical characteristics and treatment of ocular injury caused by chestnut burr. Retrospective case series study. Data of 48 patients (48 eyes) with ocular injuries caused by chestnut burrs hospitalized in Qingdao Eye Hospital were collected from January 2013 to March 2019. Read More

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http://dx.doi.org/10.3760/cma.j.cn112142-20190604-00295DOI Listing

Epidemiology and Clinical Characteristics of Episcleritis and Scleritis in Olmsted County, MN.

Am J Ophthalmol 2020 May 10. Epub 2020 May 10.

Department of Ophthalmology, Mayo Clinic College of Medicine and Science, Rochester, MN. Electronic address:

Purpose: To determine the population-based incidence and disease associations of episcleritis and scleritis in a Midwestern US population.

Design: Population-based retrospective cohort study.

Methods: All residents of Olmsted County, MN from 2006-2015 were identified using the Rochester Epidemiology Project. Read More

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http://dx.doi.org/10.1016/j.ajo.2020.04.043DOI Listing

New Potential Weapons for Refractory Scleritis in the Era of Targeted Therapy.

Mediators Inflamm 2020 17;2020:8294560. Epub 2020 Jan 17.

Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease, Rheumatology Unit of the Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.

Objective: To assess the efficacy of biologic drugs, beyond tumor necrosis factor- (TNF-) inhibitors, in the management of noninfectious refractory scleritis, either idiopathic or associated with systemic immune-mediated disorders. . This is a retrospective study assessing the efficacy of several biologic agents (rituximab, anakinra, tocilizumab, and abatacept) and the small molecule tofacitinib in the treatment of scleritis through assessment of scleral inflammation and relapses, as well as treatment impact on best-corrected visual acuity (BCVA) and safety profile. Read More

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http://dx.doi.org/10.1155/2020/8294560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201583PMC
January 2020

Escalation to Weekly Adalimumab for the Treatment of Ocular Inflammation.

Ocul Immunol Inflamm 2020 May 14:1-5. Epub 2020 May 14.

Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

: To report the outcomes of the escalation of adalimumab (ADA) dose for refractory ocular inflammatory diseases.: A retrospective case series of 15 patients (29 eyes) diagnosed with ocular inflammatory disease, including uveitis and scleritis, which was not adequately controlled with standard, every other week ADA dosing, leading to an escalation to weekly dosing.: Ten of fifteen patients escalated to weekly ADA achieved control of their inflammation; neither of the two patients increased for control of cystoid macular edema (CME) had resolution and required regional corticosteroids. Read More

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http://dx.doi.org/10.1080/09273948.2020.1749857DOI Listing

Combination of Intravenous Methotrexate and Methylprednisolone Therapy in the Treatment of Severe Ocular Inflammatory Diseases.

Ocul Immunol Inflamm 2020 May 14:1-5. Epub 2020 May 14.

Massachusetts Eye Research and Surgery Institution, Waltham, Massachusetts, USA.

: To evaluate the efficacy of intravenous methotrexate and methylprednisolone in severe, sight-threatening ocular inflammatory conditions.: This was a retrospective observational case series. Patients who had received intravenous methotrexate for ocular inflammation with at least 24 months of follow-up were included in the study. Read More

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http://dx.doi.org/10.1080/09273948.2020.1746356DOI Listing

Experience With 0.1% Tacrolimus Eye Drop for Noninfectious, Non-necrotizing Anterior Scleritis.

Eye Contact Lens 2020 May 12. Epub 2020 May 12.

Department of Ophthalmology (H.Y., H.F.), Tsurumi University School of Dental Medicine, Kanagawa, Japan; Department of Ophthalmology (H.Y.), Keio University School of Medicine, Tokyo, Japan; and Ophthalmology and Visual Science (D.M.), Faculty of Medicine Tottori University, Tottori, Japan.

Objectives: To report experience with 0.1% tacrolimus eye drops in the treatment of noninfectious, non-necrotizing anterior scleritis.

Methods: This prospective, single-arm study included nine patients (4 men and 5 women; mean age=59. Read More

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http://dx.doi.org/10.1097/ICL.0000000000000696DOI Listing

[How to approach follow-up of uveitis patients during the Covid-19 pandemic?]

J Fr Ophtalmol 2020 Jun 30;43(6):535-536. Epub 2020 Apr 30.

Service d'ophtalmologie, CHU Pitié-Salpetrière, 47-83, boulevard de l'Hôpital, 75013 Paris, France.

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http://dx.doi.org/10.1016/j.jfo.2020.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190488PMC

Delayed Onset Scleromalacia and Conjunctival Bleb Formation Following Intraoperative Mitomycin C Application during Conjunctival Melanoma Excision.

Vision (Basel) 2020 May 6;4(2). Epub 2020 May 6.

Sussex Eye Hospital, Brighton & Sussex University Hospitals NHS Trust, Eastern Road, Brighton BN2 5BF, UK.

Purpose: To present a case of delayed onset scleromalacia and conjunctival bleb formation one year after conjunctival melanoma excision with intraoperative use of mitomycin-C (MMC) and double-freeze-thaw technique.

Methods: Case report.

Results: A 69-year-old woman had a conjunctival melanoma excised by the 'no touch technique' with intraoperative application of 0. Read More

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http://dx.doi.org/10.3390/vision4020024DOI Listing

[Nodular scleritis secondary to Wegener's granulomatosis].

J Fr Ophtalmol 2020 Jun 30;43(6):568-570. Epub 2020 Apr 30.

Service d'ophtalmologie A, hôpital des spécialités, Rabat, Maroc.

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http://dx.doi.org/10.1016/j.jfo.2019.10.013DOI Listing

Ocular manifestations in rheumatoid arthritis, connective tissue disease and vasculitis: a systematic review and meta-analysis.

J Rheumatol 2020 May 1. Epub 2020 May 1.

From the Schulich School of Medicine, University of Western Ontario, St. Joseph's Health Care, London, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Canadian Rheumatology Association Research studentship, University of Western Ontario. This funding was supported through the Canadian Rheumatology Association Roche summer studentship. There are no conflicts of interest. IRB was not necessary as this was a systematic literature review. Address correspondence to Dr. Janet Pope MD MPH FRCPC, Division of Rheumatology, St. Joseph's Health Care, 268 Grosvenor St. London ON N6A 4V2,

Objective: Rheumatoid Arthritis and other rheumatic diseases may present with ocular manifestations. The purpose of our work was to determine the prevalence and type of eye involvement in rheumatoid arthritis and other connective tissue diseases through a meta-analysis and literature review.

Methods: A systematic review of the literature was performed using Medline, Web of Science, and the Cochrane library from their inceptions until January 7, 2019. Read More

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http://dx.doi.org/10.3899/jrheum.190768DOI Listing

Case 14-2020: A 37-Year-Old Man with Joint Pain and Eye Redness.

N Engl J Med 2020 04;382(18):1750-1758

From the Department of Ophthalmology, Massachusetts Eye and Ear (L.S.), the Departments of Medicine (J.H.S.), Radiology (A.J.H.), and Pathology (J.L.N., R.M.N.), Massachusetts General Hospital, and the Departments of Ophthalmology (L.S.), Medicine (J.H.S.), Radiology (A.J.H.), and Pathology (J.L.N., R.M.N.), Harvard Medical School - all in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1909623DOI Listing

Intraocular schwannoma with extrascleral extension.

Eur J Ophthalmol 2020 Apr 28:1120672120920211. Epub 2020 Apr 28.

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA.

Purpose: To report a rare case of intraocular schwannoma with extrascleral extension in a patient with juvenile idiopathic arthritis and to review the literature for this topic.

Methods: Case report.

Results: A 19-year-old male with a history of juvenile idiopathic arthritis was referred for diagnosis and management of an episcleral mass, initially thought to be focal nodular scleritis. Read More

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http://dx.doi.org/10.1177/1120672120920211DOI Listing

Effectiveness of TNF-α blockade in the treatment of refractory non-infectious scleritis: a multicentre study.

Clin Exp Rheumatol 2020 Apr 17. Epub 2020 Apr 17.

Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease, Rheumatology Unit of the Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Italy.

Objectives: To evaluate the efficacy of tumour necrosis factor (TNF)-α inhibitors in refractory non-infectious scleritis.

Methods: We carried out a retrospective study assessing the efficacy of TNF-α inhibitors in the treatment of scleritis, scleritis relapses, glucocorticoid (GC)-sparing effect, impact on best-corrected visual acuity (BCVA) and safety profile.

Results: Nineteen patients (28 eyes) were eligible for analysis. Read More

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Epidemiology of episcleritis and scleritis in urban Australia.

Clin Exp Ophthalmol 2020 Apr 12. Epub 2020 Apr 12.

Centre for Eye Research Australia, The Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.

Importance: The epidemiology of episcleritis and scleritis in Australia is largely unknown.

Background: To determine the incidence, prevalence and clinical characteristics of episcleritis and scleritis in Melbourne.

Design: Retrospective longitudinal study. Read More

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http://dx.doi.org/10.1111/ceo.13761DOI Listing

Characterization and Management of Inflammatory Eye Disease in Patients with Hidradenitis Suppurativa.

Ocul Immunol Inflamm 2020 Apr 7:1-6. Epub 2020 Apr 7.

Department of Ophthalmology & Visual Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

: To assess the spectrum and treatment outcomes of inflammatory eye disease (IED) in subjects with hidradenitis suppurativa (HS).: We conducted a single center retrospective chart review of 236 patients with HS seen for ophthalmic examination between 2013 and 2018.: Of 236 subjects with HS, 22 subjects (9. Read More

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http://dx.doi.org/10.1080/09273948.2020.1739718DOI Listing

'Solitary idiopathic choroiditis' or a tumour of scleral origin: A case report based hypothesis.

Med Hypotheses 2020 Jun 28;139:109695. Epub 2020 Mar 28.

Department of Radiodiagnosis, All India Institute Of Medical Sciences, Ansari Nagar, New Delhi 110029, India. Electronic address:

We here hypothesize the scleral origin of 'Solitary Idiopathic Choroiditis', a yellowish, nodular lesion that resembles other choroidal tumors. Systemic investigations were done to rule out causes like tuberculosis and sarcoidosis. Multimodal imaging was done for better characterization and to distinguish it from other choroidal lesions. Read More

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http://dx.doi.org/10.1016/j.mehy.2020.109695DOI Listing

Posterior Scleritis in Familial Mediterranean Fever.

Case Rep Ophthalmol 2019 Jan-Apr;10(1):134-139. Epub 2019 Apr 18.

Department of Ophthalmology, American University of Beirut, Beirut, Lebanon.

Purpose: Familial Mediterranean fever (FMF) is a monogenic autoinflammatory disease presenting as sporadic paroxysmal attacks of fever and abdominal pain. The inflammation of serosal spaces, joints, and skin is caused by the production of an abnormal protein called pyrin. Ocular pathology is scarce in FMF. Read More

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http://dx.doi.org/10.1159/000499600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098358PMC

Noninfectious Autoimmune Scleritis: Recognition, Systemic Associations, and Therapy.

Curr Rheumatol Rep 2020 Mar 26;22(4):11. Epub 2020 Mar 26.

Cleveland Clinic Lerner College of Medicine, Department of Rheumatic and Immunologic Diseases, Orthopaedic and Rheumatologic Institute, Cleveland Clinic, Cleveland, OH, USA.

Purpose Of Review: The aim of this review is to provide the information necessary for recognizing scleritis in rheumatology patients, recognize associated systemic diseases in scleritis patients referred to rheumatology, and choose the best conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) or biologic therapy, based on the most recent data.

Recent Findings: Scleritis is most often associated with systemic conditions, particularly autoimmune conditions. Rheumatologists should be most vigilant about rheumatoid arthritis and ANCA-associated vasculitis. Read More

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http://dx.doi.org/10.1007/s11926-020-0885-yDOI Listing

scleritis initially presenting as idiopathic diffuse anterior scleritis.

Oman J Ophthalmol 2020 Jan-Apr;13(1):51-52. Epub 2020 Feb 17.

Department of Uvea, Sankara Nethralaya, 18, College Road, Sankara Nethralaya, Chennai, Tamil Nadu, India.

remains the most common cause of bacterial scleritis. This report illustrates an unusual presentation of scleritis, which initially presented as diffuse anterior scleritis with anterior uveitis. The detailed laboratory work-up of the patient was negative, and the initiation of high-dose oral corticosteroid therapy led to further deterioration of clinical condition, with the appearance of a yellowish-white nodule within 3 days. Read More

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http://dx.doi.org/10.4103/ojo.OJO_256_2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050448PMC
February 2020

Retinochoroidal fold with severe discedema in a case of posterior scleritis.

Indian J Ophthalmol 2020 04;68(4):647-649

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.4103/ijo.IJO_1013_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210866PMC

Effectiveness of pharmacological agents for the treatment of non-infectious scleritis: a systematic review protocol.

Syst Rev 2020 Mar 12;9(1):54. Epub 2020 Mar 12.

Academic Unit of Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Birmingham and Midland Eye Centre, City Hospital, Dudley Road, Birmingham, B18 7QU, UK.

Background: Non-infectious scleritis is a potentially sight-threatening condition in which the sclera, the white outer layer of the eye, becomes inflamed. Whilst scleritis can be infective, the majority of cases are due to non-infectious causes, often occurring in association with an underlying systemic autoimmune or auto-inflammatory condition. Thorough systemic work-up is crucial to identify disease aetiology and exclude infection; however, a significant proportion of disease remains idiopathic with the underlying cause unknown. Read More

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http://dx.doi.org/10.1186/s13643-020-01314-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068966PMC

[Necrotizing scleritis after acanthamoeba keratitis].

Ophthalmologe 2020 Mar 11. Epub 2020 Mar 11.

Klinik für Augenheilkunde, Medizinische Fakultät, Universitätsklinikum Freiburg, Killianstr. 5, 79106, Freiburg, Deutschland.

Nodular scleritis and necrotizing scleritis are rare complications of acanthamoeba keratitis. This article presents the case of a 61-year-old female patient who had suffered from persistent keratitis in the right eye for more than 4 months. The patient was initially treated with propamidine isethionate and polyhexamethylene biguanide eye drops. Read More

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http://dx.doi.org/10.1007/s00347-020-01080-yDOI Listing

Risks of ophthalmic disorders in patients with systemic lupus erythematosus - a secondary cohort analysis of population-based claims data.

BMC Ophthalmol 2020 Mar 11;20(1):96. Epub 2020 Mar 11.

Graduate Institute of Long-term Care, Tzu Chi University of Science and Technology, Hualien, Taiwan.

Background: Systemic lupus erythematosus (SLE) can directly affect various part of the ocular system, but there was no comprehensive analysis of ophthalmic disorders of patients with SLE using population-based data. The aim of this study was to investigate the frequency and prevalence of ophthalmic disorders for ophthalmologist visits in adult patients with SLE and to evaluate the risk of dry eye syndrome, cataracts, glaucoma, episcleritis and scleritis, and retinal vascular occlusion in these patients.

Methods: The Taiwan's National Health Insurance Research Database was used to assemble a SLE cohort consisting of newly diagnosed SLE between 2000 and 2012. Read More

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http://dx.doi.org/10.1186/s12886-020-01360-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066815PMC

Scleritis With Uveal Effusion From Alirocumab.

Ann Intern Med 2020 Jun 10;172(12):834-836. Epub 2020 Mar 10.

Columbia University Irving Medical Center, New York-Presbyterian Hospital, New York, New York (R.W.C.).

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http://dx.doi.org/10.7326/L19-0815DOI Listing

Bilateral interstitial keratitis, erythema nodosum and atrial fibrillation as presenting signs of polyarteritis nodosa.

Am J Ophthalmol Case Rep 2020 Jun 21;18:100619. Epub 2020 Feb 21.

Athens Vision Eye Institute, Athens, Greece.

Purpose: To report a case of Polyarteritis Nodosa (PAN) presenting as bilateral episcleritis and interstitial keratitis along with erythema nodosum and atrial fibrillation and to review the ophthalmic literature on PAN with anterior segment findings.

Observations: A 35-year old man presented with a two-month history of bilateral episcleritis, skin lesions consistent with erythema nodosum, joint effusions and episodes of prolonged diarrhea and atrial fibrillation. Ophthalmic examination was significant for bilateral diffuse episcleral injection and nummular corneal stromal infiltrates. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044707PMC

Clinical Profile of Patients with Scleritis in Bangladesh.

Ocul Immunol Inflamm 2020 Mar 4:1-4. Epub 2020 Mar 4.

Department of Uvea, Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, India.

: To analyze clinical profile of the patients with scleritis in a tertiary care eye hospital in Bangladesh.: Retrospective analysis of 111 eyes of 79 patients of scleritis between January 2012 and May 2018.: The study observed a relative younger mean age and equal gender distribution. Read More

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http://dx.doi.org/10.1080/09273948.2020.1716026DOI Listing

A case of giant cell arteritis presenting with nodular posterior scleritis mimicking a choroidal mass.

Am J Ophthalmol Case Rep 2020 Mar 1;17:100583. Epub 2020 Jan 1.

Tennessee Retina, 345 23rd Ave N, Ste 350, Nashville, TN, 37203, USA.

Purpose: Herein we present a case of giant cell arteritis presenting with nodular posterior scleritis and exudative retinal detachment mimicking a choroidal mass.

Observations: A 67-year-old man presented with sudden onset left-sided periorbital pain, blurry vision, and a choroidal lesion in the posterior pole. Despite treatment with high-dose oral prednisone for suspected nodular posterior scleritis mimicking a choroidal mass, the vision in his left eye did not recover, and he developed optic nerve pallor on exam. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.100583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033388PMC

Multimodal Imaging in a Case of Localized Suprachoroidal Hemorrhage.

J Ophthalmic Vis Res 2020 Jan-Mar;15(1):104-108. Epub 2020 Feb 2.

Smt Kanuri Santhamma Center for Vitreo Retina Services, L. V. Prasad Eye Institute, Hyderabad, India.

Purpose: To report a case of localized suprachoroidal hemorrhage presenting as a choroidal mass.

Case Report: A 66-year-old woman presented with sudden onset pain in the right eye, one week following uneventful cataract surgery. The best corrected visual acuity (BCVA) was 20/160 and fundus examination showed a brown elevated choroidal mass temporal to the fovea in the right eye with normal retina and retinal vessels over it. Read More

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http://dx.doi.org/10.18502/jovr.v15i1.5956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001026PMC
February 2020

Nodular Scleritis Revealing Metastasis of Breast Cancer: Diagnosis Not to Be Neglected.

Case Rep Ophthalmol Med 2020 29;2020:8689463. Epub 2020 Jan 29.

Histopathology Department, Mohammed VI University Hospital, Marrakech, Morocco.

We report the case of ocular metastasis in a 48-year-old woman presenting left eye redness and pain. The patient was followed in another health institution for nodular scleritis and received systemic corticosteroids with moderate improvement. Medical history revealed that she was diagnosed three years ago with invasive ductal carcinoma of the left breast treated by tumorectomy with ganglion dissection. Read More

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http://dx.doi.org/10.1155/2020/8689463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008290PMC
January 2020

Frequently Relapsing Anterior Nodular Scleritis as the Initial Presentation of a Lethal Systemic Infection: Disseminated Tuberculosis with HIV Coinfection.

Case Rep Infect Dis 2020 31;2020:9020864. Epub 2020 Jan 31.

University Medical Unit, Teaching Hospital Karapitiya, Galle, Sri Lanka.

Background: Scleritis is a painful inflammatory ocular disease often associated with an underlying systemic illness mostly having an autoimmune aetiology. Tuberculosis usually presents as pulmonary infection, and the ocular presentation is considered to be rare. . Read More

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http://dx.doi.org/10.1155/2020/9020864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013353PMC
January 2020

Anti-Neutrophil Cytoplasmic Antibody-Associated Ocular Manifestations in Japan: A Review of 18 Patients.

Ocul Immunol Inflamm 2020 Feb 20:1-6. Epub 2020 Feb 20.

Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

ABSTARCT: To investigate ocular manifestations in patients positive for serum anti-neutrophil cytoplasmic antibodies (ANCAs) in Japan.: The clinical records of patients who had ocular manifestations and who were serum ANCA positive between 2011-2017 at Tokyo Medical and Dental University Hospital were retrospectively reviewed.: Eighteen patients were identified to be positive for serum ANCA and had ocular manifestations, including optic nerve involvement (50%), scleritis (27. Read More

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http://dx.doi.org/10.1080/09273948.2020.1712432DOI Listing
February 2020

Fulminant Acanthamoeba Endophthalmitis After Cataract Surgery-A Case Report.

Cornea 2020 Feb 14. Epub 2020 Feb 14.

Aravind Eye Hospital and Post-Graduate Institute of Ophthalmology, Coimbatore, Tamil Nadu, India.

Purpose: To report a case of Acanthamoeba endophthalmitis after an uneventful cataract surgery.

Methods: Description, management, and outcomes of a biopsy-proven case of Acanthamoeba endophthalmitis.

Results: Two days after a routine cataract surgery elsewhere, the patient presented with acute endophthalmitis diagnosed as a bacterial infection based on timing and severity. Read More

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http://dx.doi.org/10.1097/ICO.0000000000002289DOI Listing
February 2020

PATIENT WITH UNILATERAL CHOROIDAL AND SEROUS RETINAL DETACHMENT WITH A HISTORY OF TREATED PROSTATE CANCER AND UNTREATED SARCOIDOSIS.

Retin Cases Brief Rep 2020 Feb 13. Epub 2020 Feb 13.

Ophthalmology Department, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, Ohio.

Background/purpose: To report a case of unilateral choroidal detachment and serous retinal detachment in a patient with a history of untreated sarcoidosis.

Methods: Case report. The patient is a 67-year-old African American man with a history of nontreated sarcoidosis and prostate cancer. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000976DOI Listing
February 2020

Eye metastasis in lung adenocarcinoma mimicking anterior scleritis: A case report.

World J Clin Cases 2020 Jan;8(2):410-414

Department of Pathology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, Fuzhou 350014, Fujian Province, China.

Background: The eye is a rare site for lung cancer metastasis. Indeed, ocular metastasis is one of the greatest challenges to quality of life in a cancer patient. Here we present a patient with lung adenocarcinoma and ocular metastasis. Read More

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http://dx.doi.org/10.12998/wjcc.v8.i2.410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000956PMC
January 2020

Retained intraorbital wooden foreign body presenting with combined anterior and posterior scleritis.

BMJ Case Rep 2020 Feb 9;13(2). Epub 2020 Feb 9.

Cornea and Anterior Segment Sevices, LV Prasad Eye Institute, Visakhapatnam, Andhra Pradesh, India.

Penetrating injury of the orbit with a wooden stick is not an uncommon finding in ocular emergencies. A 36-year-old man presented with redness, pain in the left eye following fall from a motorcycle 3 days ago. Ocular examination showed features of combined anterior and posterior scleritis in the form of an anterior scleral nodule, retinal folds and T sign on ultrasonography. Read More

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http://dx.doi.org/10.1136/bcr-2019-232237DOI Listing
February 2020

Necrotic scleral melt and fungal keratitis-a complication of subtenon triamcinolone acetonide injection.

J Ophthalmic Inflamm Infect 2020 Jan 27;10(1). Epub 2020 Jan 27.

Dr. Shroff's Charity Eye Hospital, 5027-Kedar Nath Road, Daryaganj, New Delhi, 110002, India.

Purpose: Subtenon triamcinolone acetonide injection (STAI) is a safe drug delivery method for various ocular conditions. We report two cases of necrotic scleral melt, a rare complication of STAI.

Methods: The first patient received STAI for post-operative inflammation control and developed necrotic scleral melt at the site of STAI with superadded fungal keratitis. Read More

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http://dx.doi.org/10.1186/s12348-020-0197-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983460PMC
January 2020

Takayasu's arteritis: associated inflammatory diseases.

Clin Exp Rheumatol 2020 Mar-Apr;38 Suppl 124(2):61-68. Epub 2020 Jan 14.

Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Objectives: Case reports and series suggest that Takayasu's arteritis (TAK) can co-exist with other inflammatory disorders. We conducted a formal study to look specifically at the frequency of such inflammatory disorders in a large cohort of TAK followed by a single tertiary centre.

Methods: There were 238 patients registered with a diagnosis of TAK. Read More

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January 2020