Search Our Scientific Publications & Authors

Can J Ophthalmol 2022 Jun 15. Epub 2022 Jun 15.

Department of Ophthalmology, Hospital Saint-Sacrement, University of Quebec Centre Hospital-Laval University Research Centre, Quebec, Que. Electronic address:

Purpose: To review the clinical usefulness of chorioretinal biopsies in diagnostically undefined cases of intraocular inflammation or chorioretinal lesions.

Design: Retrospective case series.

Participants: Seven patients who underwent chorioretinal biopsies. Read More

Ocul Immunol Inflamm 2022 Jun 13:1-4. Epub 2022 Jun 13.

Department of Rheumatology, Nizams Institute of Medical Services, Hyderabad, India.

Purpose: To report a challenging case of relapsing polychondritis with bilateral diffuse scleritis, with 17-year follow-up.

Methods: Case report.

Results: A 36-year-old female presented 17 years ago with bilateral diffuse scleritis and peripheral corneal infiltrates. Read More

Cureus 2022 May 4;14(5):e24715. Epub 2022 May 4.

Internal Medicine and Nephrology, University of Oklahoma Health Sciences Center, Oklahoma City, USA.

Syphilis is a rare cause of vision loss that mostly occurs after an infection of the meninges, brain tissue, and parenchyma. Syphilis can mimic auto-immune disease like giant cell arteritis which also manifest as sudden vision loss. Spirochete can spread through sexual contact and cause painless ulcers. Read More

Clin Case Rep 2022 May 27;10(5):e05932. Epub 2022 May 27.

Division of Infectious Diseases Communicable Diseases Centre Hamad Medical Corporation Doha Qatar.

Infection following SARS-Co V-2 leading to COVID-19 disease is associated with significant morbidity and mortality. The clinical entity, COVID-19 cytokine storm syndrome (CSS) is a severe immunological manifestation of the disease associated with ominous consequences. Tocilizumab is interleukin-6 inhibitors that has been shown to hamper the catastrophic outcomes of CCS including the need for mechanical ventilation as well as reduce mortality, but the usage is limited by warnings of reactivation of potential latent infections or immune dysfunctions including severe neutropenia. Read More

J Curr Ophthalmol 2022 Jan-Mar;34(1):93-99. Epub 2022 Apr 16.

Massachusetts Eye Research and Surgery Institution, Waltham, MA, USA.

Purpose: To evaluate the B-scan ultrasound findings in unilateral posterior scleritis.

Methods: This was a retrospective observational case series at a tertiary uveitis clinic. The study population included patients who had been diagnosed with milder forms of unilateral posterior scleritis since 2010 and had B-scan ultrasonography of that eye. Read More

Eye (Lond) 2022 May 24. Epub 2022 May 24.

Department of Ophthalmology, Auckland District Health Board, Auckland, New Zealand.

Background: To examine risk factors for development of glaucoma in a large cohort of subjects with uveitis and scleritis.

Methods: Retrospective review of subjects diagnosed with uveitis or scleritis between 2006 and 2019 at Auckland District Health Board. Subjects were excluded if they had glaucoma due to another cause. Read More

Am J Ophthalmol Case Rep 2022 Jun 5;26:101573. Epub 2022 May 5.

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.

Purpose: To describe a case of sclerouveitis with exudative retinal detachment in a patient with chronic myelomonocytic leukemia.

Observations: An 82-year-old woman with chronic myelomonocytic leukemia (CMML) presented with acute painful right eye redness and decreased visual acuity. Examination revealed right eye anterior and posterior scleritis with exudative retinal detachment, as well as 2+ anterior chamber cell in the right eye and 0. Read More

Am J Ophthalmol Case Rep 2022 Jun 30;26:101570. Epub 2022 Apr 30.

Departamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Valencia, Spain.

Purpose: Human dirofilariasis cases have increased in Europe for the last few decades. We document an autochthonous case of dirofilariasis infection in the subconjunctival space of a 60-year-old Spanish man.

Observations: The patient presented with pain in his right eye, which was diagnosed as -scleritis. Read More

Case Rep Ophthalmol Med 2022 5;2022:8000944. Epub 2022 May 5.

Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

Purpose: To report three cases of culture-positive scleritis following pterygium surgery. . A retrospective study of all patients of scleritis after pterygium surgery presented from May 2017 to May 2020 was performed. Read More

Ophthalmic Genet 2022 May 16:1-7. Epub 2022 May 16.

Neuroscience Research Group NeURos, Escuela de Medicina y Ciencias de la salud, Universidad del Rosario, Bogotá, Colombia.

Purpose: Report the case of a patient with a history of central retinal artery occlusion in her right eye and amaurosis fugax associated with acute ischemic changes in her left eye related to a prothrombin G20210A gene variant, in which OCT-A was used as a diagnostic and therapeutic tool.

Case Presentation: 55-year-old woman with a history of central retinal artery occlusion in her right eye and prothrombin gene G20210A (F2) variant diagnosis. She presented to our consultation with amaurosis fugax in her left eye. Read More

BMJ Open 2022 05 11;12(5):e052833. Epub 2022 May 11.

Gastroenterology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.

Objectives: Ophthalmic conditions including anterior uveitis (AU), episcleritis and scleritis may occur in association with the inflammatory bowel diseases (IBD) as ophthalmic extraintestinal manifestations. The aim of this study was to assess the risk of a later IBD diagnosis in those presenting with IBD associated ocular inflammation (IAOI).

Design: Retrospective cohort study. Read More

Ocul Immunol Inflamm 2022 May 6:1-5. Epub 2022 May 6.

Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, India.

Purpose: To analyze clinical characteristics of scleritis in elderly patients and also compare the data with relatively younger patients with scleritis (<60 years).

Method: Retrospective analysis of medical records of patients with scleritis who visited a tertiary eye care centre between 2008 and 2018.

Result: Scleritis in ≥60 years accounted for 3% of the total scleritis cases. Read More

Am J Ophthalmol Case Rep 2022 Jun 26;26:101555. Epub 2022 Apr 26.

Department of Ophthalmology, Hospital Oftalmológico Visão Laser, 11015-003, Avenida Conselheiro Nébias, 355, Santos, SP, Brazil.

Background: Chikungunya is a matter of grave concern in Brazil. This case report describes a rare ocular manifestation in a patient with chikungunya.

Case Report: A 49-year old male diagnosed with chikungunya one month previously was being treated and followed up by a rheumatologist. Read More

Am J Ophthalmol 2022 May 2;241:139-144. Epub 2022 May 2.

From the Wilmer Eye Institute (M.K.B., B.B.B., D.A.J.), Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Center for Clinical Trials and Evidence Synthesis (D.A.J.), Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Purpose: To estimate the incidence of scleritis in Lyme disease and report clinical features.

Design: Incidence rate estimate and case series.

Methods: Data were collected from an electronic medical record on patients with scleritis presenting to the Wilmer Eye Institute between January 1, 2012 and December 31, 2020. Read More

Clin Med Res 2022 Apr 27. Epub 2022 Apr 27.

Department of Ophthalmology, Hospital Sungai Buloh, Jalan Hospital, 47000, Sungai Buloh, Selangor, Malaysia.

Conjunctival lymphomas are rare entities and may present with non-specific ocular signs that resemble inflammation. It may mimic common ocular pathologies, leading to a delay in its diagnosis and treatment. The treatment options of conjunctival lymphomas should be tailored to individuals due to their indolent nature compared to other adnexal lymphomas. Read More

Am J Ophthalmol 2022 Apr 22;241:57-63. Epub 2022 Apr 22.

From the Department of Ophthalmology, University of Colorado School of Medicine (L.I.M., A.K.R., J.L.P., P.P., E.K., K.C., A.G.P.), 1675 Aurora Ct, Aurora, CO, USA. Electronic address:

Purpose: To evaluate the new Standardization of Uveitis Nomenclature (SUN) classification criteria for uveitides by applying them to patients in an academic uveitis practice.

Design: Evaluation of classification criteria.

Methods: The charts of all patients attending the uveitis service at the University of Colorado Hospital between January 1, 2013, and December 31, 2020, were reviewed. Read More

BMC Ophthalmol 2022 Apr 18;22(1):174. Epub 2022 Apr 18.

Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.

Background: To analyse demographic, clinical features, treatment and therapeutic outcomes of pediatric uveitis and scleritis patients.

Subjects: The clinical records of pediatric uveitis and scleritis cases between January 2012 and December 2020 at a tertiary uveitis service center in Tianjin Medical University Eye Hospital (TMUEH) were reviewed.

Results: In total, 209 patients (337 eyes) were included, 49. Read More

Arq Bras Oftalmol 2022 Mar 7. Epub 2022 Mar 7.

Department of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

The aim of this study was to alert the ophthalmic community to an atypical manifestation of ocular surface squamous neoplasia, which may delay diagnosis and treatment and result in a guarded visual prognosis and significant sequelae. A 61-year-old immunocompetent man presented with an initial diagnosis of necrotizing scleritis in the right eye for 3 months. He was treated with systemic prednisone but experienced persistent pain and low visual acuity. Read More

Ocul Immunol Inflamm 2022 Apr 8:1-3. Epub 2022 Apr 8.

Department of Ophthalmology, Hospital Infanta Elena, Madrid, Spain.

Purpose: To describe a case of anterior scleritis related to SARS-CoV-2 vaccine. SARS-CoV-2 vaccines appear safe; however vaccination has triggered thromboembolic events in predisposed patients.

Methods: A retrospective case report of anterior scleritis in a woman following administration of both ChAdOx1nCoV-19 vaccine doses was studied by complete ophthalmologic examination and complementary tests. Read More

Oman J Ophthalmol 2022 Jan-Apr;15(1):95-98. Epub 2022 Mar 2.

Department of Retina and Vitreous Services, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore, Tamil Nadu, India.

A 44-year-old woman presented with complaints of pain in the right eye (RE). Fundus examination revealed disc edema in the RE along with retinal flecks sparing the macula in both eyes (BE). Fundus autofluorescence demonstrated a symmetrical pattern of white flecks in BE. Read More

Am J Ophthalmol Case Rep 2022 Jun 24;26:101497. Epub 2022 Mar 24.

Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Purpose: To report a novel case of bilateral anterior and posterior scleritis in a patient with acute myelogenous leukemia (AML).

Observations: A 69-year-old African American man was admitted to the hospital for relapse of AML. After admission, but prior to induction of chemotherapy, the patient developed ocular redness and proptosis. Read More

Int Ophthalmol 2022 Apr 2. Epub 2022 Apr 2.

Medical Corps, Israel Defense Forces, Tel Hashomer, Ramat Gan, Israel.

Purpose: To describe tele-ophthalmology consultations for primary-physicians in the IDF during the Covid-19 lockdown.

Methods: Retrospective cross-sectional study. Medical records of tele-ophthalmology consultations from March to June 2020 were reviewed. Read More

Medicina (Kaunas) 2022 Mar 21;58(3). Epub 2022 Mar 21.

Centre Hospitalier National des Quinze-Vingts, CIC 1423, DHU Sight Restore, 28 rue de Charenton, Sorbonne-Universités, Université Pierre et Marie Curie (UPMC), 75012 Paris, France.

: Secondary ocular localizations of hematological malignancies are blinding conditions with a poor prognosis, and often result in a delay in the diagnosis. : We describe a series of rare cases of ocular involvement in six patients with hematological malignancies, reportedly in remission, who presented secondary ocular localizations, challenging to diagnose. Two patients had an acute lymphoblastic leukemia (ALL) and developed either a posterior scleritis or a pseudo-panuveitis with ciliary process infiltration. Read More

Indian J Ophthalmol 2022 Apr;70(4):1197-1202

Department of Uvea, Oculolasty and Oncology, Dr Agarwal Eye Hospital and Eye Research Centre, Chennai, Tamil Nadu, India.

Purpose: To analyze the morphological outcomes of the posterior corneal opacity or "semilunar sign" in noninfectious anterior scleritis using multimodal imaging.

Methods: This was a prospective observational case series. Patients with anterior scleritis from January 2018 to January 2019 were included. Read More

Clin Med (Lond) 2022 03;22(2):100-103

Royal Free London NHS Foundation Trust, London, UK

Inflammatory eye diseases are responsible for a significant proportion of presentations to ophthalmic emergency facilities and knowledge of how to differentiate between broad categories of disease and refer accordingly is important for the practising physician. This review aims to provide an overview of inflammatory eye disease, with a focus on clinical presentation, diagnosis and management. Read More

Eur J Ophthalmol 2022 Mar 18:11206721221088259. Epub 2022 Mar 18.

Tecnologico de Monterrey, School of Medicine and Health Sciences, Institute of Ophthalmology and Visual Sciences. Monterrey, Mexico.

Objectives: Dry eye disease (DED) is arguably the most frequent ocular disease encountered in ophthalmic clinical practice. DED is frequently an underestimated condition causing a significant impact on visual function and quality of life. Many systemic autoimmune diseases (SAIDs) are related to moderate to severe DED. Read More

GMS Ophthalmol Cases 2022 8;12:Doc01. Epub 2022 Feb 8.

Department of Uvea, Aditya Birla Sankara Nethralaya, Kolkata, West Bengal, India.

We herein report a case of a young female presenting with multiple nodular scleral abscesses mimicking infective scleritis with exudative retinal detachment. Repeated diagnostic scraping for microbiological and histopathological analysis was inconclusive. The patient's systemic and collagen disease work-up was non-contributory. Read More

Ophthalmologe 2022 Mar 8. Epub 2022 Mar 8.

Universitätsaugenklinik Erlangen, FAU Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen, Deutschland.

Ocul Immunol Inflamm 2022 Mar 8:1-6. Epub 2022 Mar 8.

Department of Uveitis and Ocular Immunology, Instituto de Oftalmología FAP Conde de Valenciana, Mexico City, Mexico.

Aims: To describe demographic and clinical characteristics as well as etiologies and visual outcomes of patients with scleritis.

Methods: This is a descriptive, observational and retrospective study. We reviewed the electronic health records of patients with diagnosis of scleritis, who presented at the Institute of Ophthalmology Conde de Valenciana from January 2009 to December 2019. Read More