2,371,580 results match your criteria Science & Medicine[Journal]


Effect of Homeopathic Medicines on Intestinal Coccidia and Immune Response Cells in Spotted Rose Snapper (Lutjanus guttatus).

Homeopathy 2019 Apr 18. Epub 2019 Apr 18.

Centro de Investigaciones Biológicas del Noroeste S. C. (CIBNOR), La Paz, México.

Background:  Homeopathy has been widely applied in freshwater species but rarely in marine fish. Farm stress destabilises host-pathogen equilibrium, favouring parasites and disease. Coccidian endoparasites cause intestinal infections and cell degeneration. Read More

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http://dx.doi.org/10.1055/s-0039-1681062DOI Listing

Effects of Homeopathic Phosphorus on Encephalitozoon cuniculi-Infected Macrophages In-Vitro.

Homeopathy 2019 Apr 18. Epub 2019 Apr 18.

Research Center, Graduating Program of Environmental and Experimental Pathology, Universidade Paulista - UNIP, São Paulo, São Paulo, Brazil.

Introduction:   (), a fungus that acts as an intracellular pathogen, causes a marked neurological syndrome in many host species and is a zoonotic concern. Although no well-established treatment for this syndrome is known, previous successful clinical experience using homeopathic phosphorus has been described in which symptom remission with no mortality occurred in 40/42 animals by means of unknown immunological mechanisms. The latter observation was the main motivation for this study. Read More

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http://dx.doi.org/10.1055/s-0039-1678700DOI Listing

[Therapeutic options of obstructive urolithiasis in small ruminants].

Tierarztl Prax Ausg G Grosstiere Nutztiere 2019 Apr 18;47(2):111-115. Epub 2019 Apr 18.

Klinikum Veterinärmedizin, Klinik für Wiederkäuer (Innere Medizin und Chirurgie).

The diagnosis of obstructive urolithiasis in small ruminants frequently results in a multitude of decisions that have to be made by the consulted practitioner. Factors that influence the decision for therapy (or euthanasia) are the type of the animal's use, economic aspects and specific options of the veterinarian practice as well as emotional aspects depending on the owners of small ruminants kept as companion animals. The present article aims to present the currently available methods of therapy to facilitate a decision by the practicing veterinarian based on the present state of the science. Read More

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http://dx.doi.org/10.1055/a-0863-7008DOI Listing

Towards an Integrated Curriculum in a Speech and Language Pathology Education Programme: Development and Constituents' Initial Responses.

Folia Phoniatr Logop 2019 Apr 18:1-12. Epub 2019 Apr 18.

Division of Speech and Language Pathology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.

Background: A traditional curricular structure may challenge integration between foundational and clinical sciences in speech and language pathology (SLP) education. This project aimed to increase curriculum integration at a Swedish SLP education programme.

Methods: Learning outcomes in the existent curriculum were copied from their original courses and re-structured with reference to vertical tracks, in order to address them within and across years of study. Read More

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http://dx.doi.org/10.1159/000497609DOI Listing

House Dust Mite-Induced Allergic Lung Inflammation Is Not Exacerbated in Sickle Cell Disease Mice.

Int Arch Allergy Immunol 2019 Apr 18:1-9. Epub 2019 Apr 18.

Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut, USA,

Aim: Asthma appears to be a common comorbid condition in children with sickle cell disease (SCD), and such individuals may be at a higher risk for increased morbidity and mortality. However, several reports have indicated that asthma severity is not particularly high in those with SCD, and airway hyperreactivity and wheeze may be independently associated with SCD. In SCD mice, exacerbated allergic airway disease (AAD) has been observed in response to the model antigen ovalbumin (OVA). Read More

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https://www.karger.com/Article/FullText/499043
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http://dx.doi.org/10.1159/000499043DOI Listing
April 2019
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ADMM-based deep reconstruction for limited-angle CT.

Phys Med Biol 2019 Apr 18. Epub 2019 Apr 18.

College of Mathematics and Statistics, Chongqing University, Chongqing, CHINA.

In the real applications of computed tomography (CT) imaging, the projection data of the scanned objects are usually acquired within a limited-angle range because of the limitation of the scanning condition. Under these circumstances, conventional analytical algorithms, such as filtered back-projection (FBP), do not work because the projection data are incomplete. The regularization method has proven to be effective for tomographic reconstruction from under-sampled measurements. Read More

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http://dx.doi.org/10.1088/1361-6560/ab1abaDOI Listing

Longitudinal and transverse magnetoresistance of SrTiO3 with a single closed Fermi surface.

J Phys Condens Matter 2019 Apr 18. Epub 2019 Apr 18.

Department of Engineering Science, Denki Tsushin Daigaku, 1-5-1 Chofugaoka, Chofu, Tokyo, 182-8585, JAPAN.

The magnetoresistance (MR) of SrTiO<sub>3</sub> is theoretically investigated based on the Boltzmann equation by considering its detailed band structure. The formula for MR proposed by Mackey and Sybert is extended to be applicable to a system with an arbitrarily shaped Fermi surface. It is shown that the angular dependence of the diagonal component of the mass tensor causes transverse MR, whereas that of the offdiagonal component causes longitudinal MR with only a single closed Fermi surface, which overturns the textbook understanding of MR. Read More

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http://dx.doi.org/10.1088/1361-648X/ab1b05DOI Listing

Obesity Induces Ovarian Inflammation and Reduces Oocyte Quality.

Reproduction 2019 Apr 1. Epub 2019 Apr 1.

J Wood, Animal Science, University of Nebraska, Lincoln, 68583-0908, United States.

In the US, 36.5 percent of women between the ages of 20-39 are obese. This obesity results in not only metabolic disorders including type II diabetes and cardiovascular disease, but also impaired female fertility. Read More

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http://dx.doi.org/10.1530/REP-18-0583DOI Listing

Inorganic soil amendments alter seedling performance of native plant species in post-mining arid zone rehabilitation.

J Environ Manage 2019 Apr 15;241:179-186. Epub 2019 Apr 15.

The University of Western Australia, School of Biological Sciences, Crawley, 6009, WA, Australia; (b)Kings Park Science, Department of Biodiversity, Conservation and Attractions, Kings Park, 6005, WA, Australia; The University of New South Wales, Centre for Ecosystem Science, School of Biological, Earth and Environmental Sciences, Randwick, 2052, NSW, Australia.

Rehabilitation of degraded drylands is challenged by environmental and anthropogenic constraints, such as limited availability of locally-sourced topsoil and poor quality alternative soil substrates. Current rehabilitation practices, at times, utilise inorganic soil amendments to improve the physicochemical and biological characteristics of reconstructed soil profiles. These approaches may be appropriate for dryland rehabilitation, but there is limited research available regarding the benefits of using these amendments. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.04.022DOI Listing

Intraoperative ultrasonography (ioUS) characteristics of focal cortical dysplasia (FCD) type II b.

Seizure 2019 Mar 12;69:80-86. Epub 2019 Mar 12.

Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico C. Besta, Milan, Italy; Department of Neurological Surgery, Johns Hopkins Medical School, Baltimore, MD, USA.

Purpose: Focal cortical dysplasia (FCD) is one of the major causes of drug-resistant epilepsy. Surgery has proved to be the treatment of choice, however up to a third of patients experience only partial resection. Ill-defined borders and lesions embedded in eloquent areas are two of the main drawbacks of FCD surgery. Read More

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http://dx.doi.org/10.1016/j.seizure.2019.02.020DOI Listing

Dietary inflammatory index is positively associated with serum high-sensitivity C-reactive protein in a Korean adult population.

Nutrition 2018 Nov 23;63-64:155-161. Epub 2018 Nov 23.

Cancer Prevention and Control Program, University of South Carolina, Columbia, South Carolina, USA; Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, USA; Connecting Health Innovations LLC, Columbia, South Carolina, USA.

Objective: To our knowledge, only a few studies have explored the relationship between the inflammatory potential of diet and serum inflammatory markers in Korean adults. The likely novel aim of this study was to examine the association between the dietary inflammatory index (DII) and serum high-sensitivity C-reactive protein (hs-CRP) in a Korean adult population.

Methods: A cross-sectional study was conducted using the data set from the Korea National Health and Nutrition Examination Survey (KNHANES) 2015. Read More

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http://dx.doi.org/10.1016/j.nut.2018.11.016DOI Listing
November 2018

Potent and selective EGFR inhibitors based on 5-aryl-7H-pyrrolopyrimidin-4-amines.

Bioorg Chem 2019 Apr 11;88:102918. Epub 2019 Apr 11.

Department of Chemistry, Norwegian University of Science and Technology (NTNU), NO-7491 Trondheim, Norway. Electronic address:

The epidermal growth factor receptor represents an important target in cancer therapy, and low molecular weight inhibitors based on quinazolines have reached the marked. Herein we report on a new scaffold, 5-aryl-7H-pyrrolo[2,3-d]pyrimidin-4-amines, and show that when employing (S)-phenylglycinol as C-4 substituent, potent inhibitors can be made. The two most active inhibitors have suitable druglike properties, were equipotent with Erlotinib in Ba/F3 cell studies, and showed lower cross reactivity than Erlotinib in a panel of 50 kinases. Read More

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http://dx.doi.org/10.1016/j.bioorg.2019.102918DOI Listing

Lysophospholipid profiles of apolipoprotein E-deficient mice reveal potential lipid biomarkers associated with atherosclerosis progression using validated UPLC-QTRAP-MS/MS-based lipidomics approach.

J Pharm Biomed Anal 2019 Apr 5;171:148-157. Epub 2019 Apr 5.

Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, China. Electronic address:

Lysophospholipids (Lyso-PLs) are lipid-derived signaling molecules which were demonstrated to have a strong correlation with the progression of atherosclerosis. In this study, we investigated the influence of high-fat diet on Lyso-PL profiles of atherosclerosis-prone apolipoprotein E-deficient (ApoE) mice and wild type C57BL/6 J mice to find out the potential biomarkers associated with atherosclerosis. Firstly, the quantitative profiling method for Lyso-PLs based on ultra-performance liquid chromatography-quadrupole linear ion trap mass spectrometry (UPLC-QTRAP-MS/MS) was established and validated. Read More

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http://dx.doi.org/10.1016/j.jpba.2019.03.062DOI Listing

G-quadruplex and duplex DNA binding studies of novel Ruthenium(II) complexes containing ascididemin ligands.

J Inorg Biochem 2019 Apr 6;196:110681. Epub 2019 Apr 6.

Shanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, Shanghai 200092, PR China. Electronic address:

In this paper, three new Ruthenium(II) polypyridyl complexes containing ascididemin (ASC) as main ligand have been synthesized and characterized. Their interactions with different G-quadruplex (Htelo, c-myc and c-kit) (Htelo: human telomeric DNA, c-myc: cellular-myelocytomatosis viral oncogene, c-kit: oncogene c-kit promoter sequences) and duplex (ds26) DNA sequences were comparatively studied with the free ligand ASC by a series of spectroscopic techniques including UV-vis (ultraviolet-visible) spectroscopy, FID (fluorescent intercalator displacement) assay, and FRET (fluorescence resonance energy transfer) melting assay. Molecular docking studies were also performed to support the binding mode of the compounds with G-quadruplex DNA. Read More

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http://dx.doi.org/10.1016/j.jinorgbio.2019.03.021DOI Listing

Bioavailable Sr/Sr in European soils: A baseline for provenancing studies.

Sci Total Environ 2019 Mar 31;672:1033-1044. Epub 2019 Mar 31.

Eurogeosurveys, Brussels, Belgium.

We present Sr/Sr isotope ratios for ~1200 selected soil samples, collected by the GEMAS consortium from grazing (Gr) and agricultural (Ap) soils in Europe with the aim to better understand the strontium isotope distribution in the bioavailable fraction of the top-soil and its potential for provenancing applications. Spatial analysis shows that there is a clear distinction between coastal (<100 km) and non-coastal (>100 km) samples in their variance and that this variance is mirrored in the sodium concentration, suggesting an important but highly variable contribution from seaspray. We present two Sr/Sr maps at 25 km × 25 km scale: one based solely on the measured data using a classical kriging approach and one based on a Random Forest model using complementary GEMAS data to predict the strontium isotope composition at the remaining 3000+ GEMAS sampling locations, including appropriate uncertainty assessment. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00489697193138
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http://dx.doi.org/10.1016/j.scitotenv.2019.03.387DOI Listing
March 2019
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STIM1 structure-function and downstream signaling pathways.

Cell Calcium 2019 Apr 8;80:101-102. Epub 2019 Apr 8.

Institute of Biophysics, Johannes Kepler University Linz, Life Science Center, Gruberstrasse 40, 4020 Linz, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ceca.2019.01.004DOI Listing

Exposure effects of endotoxin-free titanium-based wear particles to human osteoblasts.

J Mech Behav Biomed Mater 2019 Apr 10;95:143-152. Epub 2019 Apr 10.

Department of Physics, UNESP, São Paulo State University, 17033-360, Bauru, SP, Brazil.

Titanium-based materials are widely employed by the biomedical industry in orthopedic and dental implants. However, when placed into the human body, these materials are highly susceptible to degradation processes, such as corrosion, wear, and tribocorrosion. As a consequence, metallic ions or particles (debris) may be released, and although several studies have been conducted in recent years to better understand the effects of their exposure to living cells, a consensual opinion has not yet been obtained. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.04.003DOI Listing

Cluster binding studies with two anti-Thomsen-Friedenreich (anti-core-1, CD176, TF) antibodies: Evidence for a multiple TF epitope.

Int Immunopharmacol 2019 Apr 15;72:186-194. Epub 2019 Apr 15.

Glycotope GmbH, 13125 Berlin-Buch, Germany. Electronic address:

Antibodies to carbohydrate epitopes are often of the IgM isotype and require multiple binding for sufficient avidity. Therefore clusters of epitopes are preferred antigenic sites in these cases. We have examined the type of clusters recognized by two anti-Thomsen-Friedenreich (TF, core-1, CD176) IgM antibodies, NM-TF1 and NM-TF2, using several different sets of TF-carrying synthetic glycoconjugates in ELISA experiments. Read More

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http://dx.doi.org/10.1016/j.intimp.2019.03.058DOI Listing

Elucidating the biodegradation mechanism of tributyl phosphate (TBP) by Sphingomonas sp. isolated from TBP-contaminated mine tailings.

Environ Pollut 2019 Apr 3;250:284-291. Epub 2019 Apr 3.

School of Energy and Environmental Engineering, University of Science and Technology Beijing, Beijing, 100083, PR China; Beijing Key Laboratory on Resource-oriented Treatment of Industrial Pollutants, Beijing, 100083, China.

Tributyl phosphate (TBP) is recognised as a global environmental contaminant because of its wide use in floatation reagents, nuclear fuel reprocessing and plasticisers. This contaminant is hardly degraded by hydrolysis in the environment due to its special physicochemical properties. In this study, one TBP-degrading strain was isolated from TBP-contaminated abandoned mine tailings, and 16S rRNA identification revealed that the strain belonged to the genus Sphingomonas. Read More

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http://dx.doi.org/10.1016/j.envpol.2019.03.127DOI Listing

Mediation of functional gene and bacterial community profiles in the sediments of eutrophic Chaohu Lake by total nitrogen and season.

Environ Pollut 2019 Apr 10;250:233-240. Epub 2019 Apr 10.

CAS Key Laboratory of Urban Pollutant Conversion, Department of Applied Chemistry, University of Science & Technology of China, Hefei, 230026, China. Electronic address:

Microbes in sediments contribute to nutrient release and play an important role in lake eutrophication. However, information about the profiles of functional genes and bacterial communities and the most important environmental factor affecting them in the sediments of eutrophic lake remains unrevealed. In this work, the real-time fluorescent quantitative polymerase chain reaction (qPCR) assay and 16S ribosomal RNA gene next generation sequencing analysis were used to explore the profiles of functional genes and bacterial communities in the sediments of Chaohu Lake. Read More

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http://dx.doi.org/10.1016/j.envpol.2019.04.028DOI Listing

The three 'B' of fish mercury in China: Bioaccumulation, biodynamics and biotransformation.

Environ Pollut 2019 Apr 10;250:216-232. Epub 2019 Apr 10.

Department of Ocean Science, The Hong Kong University of Science and Technology (HKUST), Clear Water Bay, Kowloon, Hong Kong, HKUST Shenzhen Research Institute, Shenzhen, 518057, China. Electronic address:

Mercury (Hg) is a global toxic pollutant and has raised the world's attention for decades. In this study, we reviewed the fish mercury levels in China (both marine and freshwater, as well as wild and farmed) documented over the past decade and their controlling environmental and biological factors. China is the largest contributor of global Hg cycling and the largest nation for the consumption and export of fish and fish product, thus Hg level in fish becomes a critical issue for food safety and public health. Read More

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http://dx.doi.org/10.1016/j.envpol.2019.04.034DOI Listing
April 2019
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Exploring the potency of integrating semi-batch operation into lipid yield performance of Chlamydomonas sp. Tai-03.

Bioresour Technol 2019 Apr 11;285:121331. Epub 2019 Apr 11.

Department of Chemical Engineering, National Cheng Kung University, Tainan 701, Taiwan; Research Center for Circular Economy, National Cheng Kung University, Tainan 701, Taiwan; Research Center for Energy Technology and Strategy, National Cheng Kung University, Tainan 701, Taiwan; College of Engineering, Tunghai University, Taichung 407, Taiwan.

Third generation biofuels, also known as microalgal biofuels, are promising alternatives to fossil fuels. One attractive option is microalgal biodiesel as a replacement for diesel fuel. Chlamydomonas sp. Read More

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http://dx.doi.org/10.1016/j.biortech.2019.121331DOI Listing

Micro-aeration in anode chamber promotes p-nitrophenol degradation and electricity generation in microbial fuel cell.

Bioresour Technol 2019 Mar 27;285:121291. Epub 2019 Mar 27.

MOE, Key Laboratory of Cell Activities and Stress Adaptations, School of Life Science, Lanzhou University, Lanzhou 730000, Gansu, PR China; Key Laboratory for Resources Utilization Technology of Unconventional Water of Gansu Province, Gansu Academy of Membrane Science and Technology, Lanzhou 730020, Gansu, PR China. Electronic address:

Biodegradation of recalcitrant organic compounds in microbial fuel cell (MFC) is limited, due to its strong electron affinity and persisted in anaerobic condition. In this study, Pseudomonas monteilii LZU-3 degraded p-nitrophenol (PNP) and generated current at 100 mg L of PNP in anode MFC with the addition of oxygen. The highest PNP degradation was 4, 37. Read More

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http://dx.doi.org/10.1016/j.biortech.2019.03.130DOI Listing

Synergetic effect of combined ensiling of freshly harvested and excessively wilted maize stover for efficient biogas production.

Bioresour Technol 2019 Apr 11;285:121338. Epub 2019 Apr 11.

College of Engineering (Key Laboratory for Clean Renewable Energy Utilization Technology, Ministry of Agriculture), China Agricultural University, Beijing 100083, PR China; Yantai Institute, China Agricultural University, Yantai 264032, Shandong, PR China.

This study investigated the synergetic effects of ensiling freshly harvested maize stover (FHM) and excessively wilted maize stover (EWM) on biogas production. FHM and EWM were mixed in various proportions to obtain dry matter (DM) contents of 30%, 35% and 40%. For reference, FHM alone was ensiled and stored in open-air. Read More

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http://dx.doi.org/10.1016/j.biortech.2019.121338DOI Listing

Degradation pathways and kinetics of anthraquinone compounds along with nitrate removal by a newly isolated Rhodococcus pyridinivorans GF3 under aerobic conditions.

Bioresour Technol 2019 Apr 11;285:121336. Epub 2019 Apr 11.

State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China.

A novel Rhodococcus pyridinivorans GF3 capable of degrading anthraquinone compounds (ACs) was isolated from 1-amino-4-bromoanthraquinone-2-sulfonic acid contaminated soil under aerobic conditions. Strain GF3 could degrade nine ACs at 150 rpm and 30 °C. LC-MS analysis showed that ACs were degraded via catechol and salicylic acid-produced pathways, which were different from previously reported phthalic acid-produced pathway. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09608524193055
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http://dx.doi.org/10.1016/j.biortech.2019.121336DOI Listing
April 2019
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Chronic exposure to green light aggravates high-fat diet-induced obesity and metabolic disorders in male mice.

Ecotoxicol Environ Saf 2019 Apr 15;178:94-104. Epub 2019 Apr 15.

State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 211198, PR China; School of Life Science and Technology, China Pharmaceutical University, Nanjing, 211198, PR China; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, 210023, PR China. Electronic address:

Light is involved in many critical physiological or biochemical processes of human beings, such as visual sensing and the production of vitamin D. Recent studies have showed that the lights of different wavelengths have a profound influence in life activities. For example, blue light promotes alertness, whereas green light (GL) induces sleep in mice. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.04.013DOI Listing

Trophic transfer of cyclic methyl siloxanes in the marine food web in the Bohai Sea, China.

Ecotoxicol Environ Saf 2019 Apr 15;178:86-93. Epub 2019 Apr 15.

International Joint Research Centre for Persistent Toxic Substances (IJRC-PTS), College of Environmental Science and Engineering, Dalian Maritime University, Dalian, 116026, China. Electronic address:

Trophic transfer of cyclic methyl siloxanes (CMS) in aquatic ecosystems is an important criterion for assessing its environmental risks. This study researched the trophic transfer of four CMS (octamethylcyclotetrasiloxane (D), decamethylcyclopentasiloxane (D), dodecamethylcyclohexasiloxane (D), and tetradecamethylcycloheptasiloxane (D)) in marine food web from zooplankton up to seabirds in the Chinese Bohai Sea. In the zooplankton-invertebrate-fish-seabird based food web, the significant trophic magnifications were found for D to D (D: R = 0. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.04.034DOI Listing

Seasonal variations of NPAHs and OPAHs in PM at heavily polluted urban and suburban sites in North China: Concentrations, molecular compositions, cancer risk assessments and sources.

Ecotoxicol Environ Saf 2019 Apr 15;178:58-65. Epub 2019 Apr 15.

Environment Research Institute, Shandong University, Qingdao, Shandong 266237, China.

16 nitrated polycyclic aromatic hydrocarbons (NPAHs) and 5 oxygenated polycyclic aromatic hydrocarbons (OPAHs) in PM at two locations in Northern China were analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). Sampling was conducted at an urban site in Shandong University in Jinan (SDU) and a suburban site in Qixingtai in Jinan (QXT) in March, June, September and December in 2016. Overall, the concentrations of NPAHs and OPAHs were higher at SDU (1. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.04.009DOI Listing

Insights into selenate removal mechanism of hydrogen-based membrane biofilm reactor for nitrate-polluted groundwater treatment based on anaerobic biofilm analysis.

Ecotoxicol Environ Saf 2019 Apr 15;178:123-129. Epub 2019 Apr 15.

College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, China. Electronic address:

The selenate removal mechanism of hydrogen-based membrane biofilm reactor (MBfR) for nitrate-polluted groundwater treatment was studied based on anaerobic biofilm analysis. A laboratory-scale MBfR was operated for over 60 days with electron balance, structural analysis, and bacterial community identification. Results showed that anaerobic biofilm had an excellent removal of both selenate (95%) and nitrate (100%). Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.04.005DOI Listing

A review on biochar modulated soil condition improvements and nutrient dynamics concerning crop yields: Pathways to climate change mitigation and global food security.

Chemosphere 2019 Mar 29;227:345-365. Epub 2019 Mar 29.

Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.

The beneficial role of biochar on improvement of soil quality, C sequestration, and enhancing crop yield is widely reported. As such there is not much consolidated information available linking biochar modulated soil condition improvement and soil nutrient availability on crop yields. The present review paper addresses the above issues by compilation of world literature on biochar and a new dimension is introduced in this review by performing a meta-analysis of published data by using multivariate statistical analysis. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2019.03.170DOI Listing

Molecular cloning and mRNA expression of IFIT5 in tissues of ducklings infected with virulent duck hepatitis A virus type 3.

Res Vet Sci 2019 Apr 8;124:256-262. Epub 2019 Apr 8.

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, Heilongjiang Province, PR China; Northeastern Science Inspection Station, China Ministry of Agriculture Key Laboratory of Animal Pathogen Biology, Northeast Agricultural University, Harbin 150030, PR China. Electronic address:

Interferon-induced proteins with tetratricopeptide repeats (IFITs) are a family of proteins strongly induced downstream of type I interferon signaling. The function of IFITs has been investigated extensively in mammals. IFIT5 is the sole protein in this family found in birds and little information is available about the function of avian IFIT5. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00345288183132
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http://dx.doi.org/10.1016/j.rvsc.2019.04.003DOI Listing
April 2019
1 Read

Superparamagnetic iron oxide nanoparticles of curcumin enhance gemcitabine therapeutic response in pancreatic cancer.

Biomaterials 2019 Apr 8;208:83-97. Epub 2019 Apr 8.

Department of Pharmaceutical Sciences and Center for Cancer Research, University of Tennessee Health Science Center, Memphis, USA. Electronic address:

Pancreatic cancer is a complex disease accounting for fibrotic tumors and an aggressive phenotype. Gemcitabine (GEM) is used as a standard therapy, which develops chemoresistance leading to poor patient outcome. We have recently developed a superparamagnetic iron oxide nanoparticle (SPION) formulation of curcumin (SP-CUR), which is a nontoxic, bioactive anti-inflammatory/anti-cancer agent for its enhanced delivery in tumors. Read More

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http://dx.doi.org/10.1016/j.biomaterials.2019.04.005DOI Listing

Highly photostable two-photon NIR AIEgens with tunable organelle specificity and deep tissue penetration.

Biomaterials 2019 Apr 9;208:72-82. Epub 2019 Apr 9.

HKUST-Shenzhen Research Institute, No. 9 Yuexing 1st RD, South Area, Hi-tech Park, Nanshan, Shenzhen, 518057, China; Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute for Advanced Study, Institute of Molecular Functional Materials, And Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, 999077, China; Center for Aggregation-Induced Emission, SCUT-HKUST Joint Research Institute, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou, 510640, China. Electronic address:

Photostability is a particularly important parameter for fluorescence imaging especially long-term dynamic tracking in live samples. However, many organic fluorophores show poor photostability under one-photon and two-photon continuous irradiation. In addition, these traditional fluorophores also suffer from aggregation-caused quenching (ACQ) in aggregate state in insolvable water environment. Read More

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http://dx.doi.org/10.1016/j.biomaterials.2019.04.002DOI Listing

Environmental impacts of dietary quality improvement in China.

J Environ Manage 2019 Apr 15;240:518-526. Epub 2019 Apr 15.

Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, 100084, China.

Dietary-related risks rank top among all the health risks in many countries. The 2nd United Nations Sustainable Development Goal aims to end hunger, achieve food security and improved nutrition and promote sustainable agriculture. Yet whether improving nutritional quality also benefits the environment is still under-explored, particularly for developing countries. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.03.106DOI Listing

Establishing treatment optimisation as part of personalised medicine development.

Eur J Cancer 2019 Apr 15;113:96-97. Epub 2019 Apr 15.

Member of the European Parliament, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.ejca.2019.03.014DOI Listing

Decomplexation removal of Ni(II)-citrate complexes through heterogeneous Fenton-like process using novel CuO-CeO-CoO composite nanocatalyst.

J Hazard Mater 2019 Apr 9;374:167-176. Epub 2019 Apr 9.

Department of Environmental Engineering, College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, PR China.

A novel CuO-CeO-CoO nanocatalyst was prepared for heterogeneous Fenton-like reaction to break the Ni-chelate into free Ni in electroless nickel plating wastewater, followed by separation of Ni in an insoluble form. The composite nanocatalysts prepared by co-precipitation method were characterized by XRD, TEM, and XPS, et al. Its catalytic activity as Fenton-like reagent was evaluated by the removal efficiency of Ni(II)-citrate after decomplexation and postprecipitation treatment. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03043894193045
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http://dx.doi.org/10.1016/j.jhazmat.2019.04.031DOI Listing
April 2019
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Enhanced superoxide sensitivity in organic field-effect transistor sensors by introducing nanoclay-polyphenol-polymer hybrid sensing channels.

J Hazard Mater 2019 Apr 2;374:159-166. Epub 2019 Apr 2.

Organic Nanoelectronics Laboratory and KNU Institute for Nanophotonics Applications (KINPA), Department of Chemical Engineering, School of Applied Chemical Engineering, Kyungpook National University, Daegu, 41566, Republic of Korea. Electronic address:

Here we report that nanoclay-polyphenol-polymer hybrid sensing channels can greatly enhance the sensitivity for hazardous reactive oxygen species (ROS) in organic field-effect transistor (OFET) sensors. The hybrid layers were prepared by introducing nanoclay into the binary mixtures of poly(3-hexylthiophene) (P3HT) and rutin (a polyphenol) at various weight ratios. The presence of nanoclay improved the P3HT crystallinity in the hybrid films, which contributed to the increased drain current and well-maintained hole mobility even at the reduced amount of charge-transporting P3HT part. Read More

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http://dx.doi.org/10.1016/j.jhazmat.2019.04.013DOI Listing

Comparative transcriptome analysis provides insights into the distinct germination in sheepgrass (Leymus chinensis) during seed development.

Plant Physiol Biochem 2019 Apr 13;139:446-458. Epub 2019 Apr 13.

Key Laboratory of Plant Resources, Institute of Botany, The Chinese Academy of Sciences, Beijing, China. Electronic address:

Sheepgrass (Leymus chinensis ((Trin.) Tzvel)) is an important perennial forage grass that is widely distributed in the Eurasia steppe. The seed germination percentage show significant variation among the different germplasm in sheepgrass. Read More

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http://dx.doi.org/10.1016/j.plaphy.2019.04.007DOI Listing

Bone char as a green sorbent for removing health threatening fluoride from drinking water.

Environ Int 2019 Apr 15;127:704-719. Epub 2019 Apr 15.

Research and Engineering Services, Toowoomba, QLD, 4350, Australia.

Millions of people around the world suffer from or prone to health problems caused by high concentration of fluoride in drinking water sources. One of the environmentally friendly and cost-effective ways for removing fluoride is the use of bone char. In this review, the structural properties and binding affinity of fluoride ions from different water sources was critically discussed. Read More

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http://dx.doi.org/10.1016/j.envint.2019.03.065DOI Listing

Refining memory assessment of elderly people with cognitive impairment: Insights from the short-term memory binding test.

Arch Gerontol Geriatr 2019 Apr 1;83:114-120. Epub 2019 Apr 1.

Department of Basic Psychology II (Cognitive Processes), Faculty of Psychology, Complutense University of Madrid, Spain.

Alzheimer's disease (AD) affects temporary memory for bound features more remarkably than for individual features. Such selective impairments manifest from presymptomatic through dementia stages via titration procedures. A recent study suggested that without titration and with high memory load the binding selectivity may disappear in people at risk of AD such as those with Mild Cognitive Impairment (MCI). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01674943193008
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http://dx.doi.org/10.1016/j.archger.2019.03.025DOI Listing
April 2019
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Association between self-reported hearing impairment, use of a hearing aid and performance of instrumental activities of daily living.

Arch Gerontol Geriatr 2019 Apr 6;83:101-105. Epub 2019 Apr 6.

Semillero de Neurociencias y Envejecimiento, Ageing Institute, Medical School, Pontificia Universidad Javeriana, Bogotá, Colombia; Geriatric Epidemiology Research Department, Instituto Nacional De Geriatría, México City, Mexico; Geriatric Medicine Research Unit, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address:

Background And Purpose: Age-related hearing loss is a prevalent condition among the growing elderly population, which has been associated with both cognitive decline and decreased daily functioning. Decreased functioning is linked to lower performance, predominantly regarding instrumental activities of daily living (IADLs). The present study aims to explore the association between hearing loss and impairment in IADLs. Read More

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http://dx.doi.org/10.1016/j.archger.2019.04.001DOI Listing

In-vitro blood and vascular compatibility of sirolimus-eluting organic/inorganic hybrid stent coatings.

Colloids Surf B Biointerfaces 2019 Apr 9;179:405-413. Epub 2019 Apr 9.

Research Institute of Advanced Manufacturing Technology, Korea Institute of Industrial Technology, Incheon, 21999, Republic of Korea. Electronic address:

The surface characteristics of coronary stents play a pivotal role in inhibiting in-stent restenosis and late-stent thrombosis. In this study, a sol-gel-derived silica xerogel-chitosan hybrid coating was applied to Co-Cr stent and was reported, for the first time, as a biocompatible drug delivery tool in vascular stent application. A dense and uniform chitosan-silica xerogel hybrid coating (<1-μm thick) was applied on bare Co-Cr material. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.018DOI Listing

Formulation, clinical and histopathological assessment of microemulsion based hydrogel for UV protection of skin.

Colloids Surf B Biointerfaces 2019 Apr 8;179:393-404. Epub 2019 Apr 8.

Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, P.O. Box: 91388-13944, Islamic Republic of Iran.

The aim of this study was to prepare a microemulsion based hydrogel containing sesame oil and evaluate its topical application in preventing the harmful effects of UV radiation on the guinea pig's skin using histopathologic and clinical findings. Sesame oil with high antioxidant content and unique chemical and physiological properties is a suitable candidate for the evolution of UV protection on skin. Applying this natural oil in microemulsion formulation containing particles with nanometer size can enhance its efficacy. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.015DOI Listing

MiR-219a-5p enhances cisplatin sensitivity of human non-small cell lung cancer by targeting FGF9.

Biomed Pharmacother 2019 Apr 15;114:108662. Epub 2019 Apr 15.

Department of Cardiothoracic Surgery, Hwamei Hospital, University of Chinese Academy Of Science , Ningbo, Zhejiang, China.

Cisplatin (DDP) resistance is a major obstacle in the treatment of non-small cell lung cancer (NSCLC). MicroRNA-219a-5p (miR-219a-5p) has been reported to be a tumor suppressor in several cancers, but whether it regulates chemosensitivity in NSCLC remains unclear. Here, using quantitative real time PCR analysis, we observed that miR-219a-5p was down-regulated in responding tumor tissues compared with that in non-responding tumor tissues from NSCLC patients received DDP-based chemotherapy. Read More

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http://dx.doi.org/10.1016/j.biopha.2019.108662DOI Listing

Autophagy represses fascaplysin-induced apoptosis and angiogenesis inhibition via ROS and p8 in vascular endothelia cells.

Biomed Pharmacother 2019 Apr 15;114:108866. Epub 2019 Apr 15.

School of Biological Science and Technology, University of Jinan, Jinan, 250022, China.

Fascaplysin is a natural product isolated from marine sponges that exhibits broad anticancer activity. Previous studies revealed that fascaplysin-induced apoptosis and angiogenesis inhibition in vascular endothelial cells contributed to its anticancer activity. Accumulating evidence indicates that autophagy plays a significant role in mediating the function of vascular endothelial cells (VECs) and the response to cancer therapy. Read More

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http://dx.doi.org/10.1016/j.biopha.2019.108866DOI Listing

Molecular characterization of manganese superoxide dismutase (MnSOD) from sterlet Acipenser ruthenus and its responses to Aeromonas hydrophila challenge and hypoxia stress.

Comp Biochem Physiol A Mol Integr Physiol 2019 Apr 15. Epub 2019 Apr 15.

National Freshwater Fisheries Engineering Technology Research Center, Ministry of Science and Technology of China, Beijing Key Laboratory of Fishery Biotechnology (No.BZ0301), Beijing Fisheries Research Institute, Beijing 100068, China. Electronic address:

A novel gene encoding the mitochondrial manganese superoxide dismutase from sterlet Acipenser ruthenus (Ar-MnSOD) was cloned. The full-length cDNA of MnSOD was of 1040 bp with a 672 bp open reading frame encoding 224 amino acids and the deduced amino acid sequence was located in mitochondria. Sequence comparison analysis showed that Ar-MnSOD was highly similar to MnSODs of invertebrates and vertebrates, especially those of freshwater Cyprinidae fishes and mammals. Read More

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http://dx.doi.org/10.1016/j.cbpa.2019.04.010DOI Listing

Evidence for sea spray effect on oxygen stable isotopes in bone phosphate - Approximation and correction using Gaussian Mixture Model clustering.

Sci Total Environ 2019 Apr 10;673:668-684. Epub 2019 Apr 10.

Ludwig Maximilian University Munich, Faculty of Biology, Department of Biology I, Anthropology and Human Genomics, Großhaderner Straße 2, 82152 Planegg-Martinsried, Germany.

Palaeobiodiversity research based on stable isotope analysis in coastal environments can be severely hampered by the so-called "sea spray" effect. This effect shifts the isotopic signal of terrestrial individuals towards too marine values. It is commonly agreed upon that sea spray influences sulphur stable isotopes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00489697193159
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http://dx.doi.org/10.1016/j.scitotenv.2019.04.072DOI Listing
April 2019
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An integrated statistical and deterministic hydrologic model for analyzing trace organic contaminants in commercial and high-density residential stormwater runoff.

Sci Total Environ 2019 Apr 6;673:656-667. Epub 2019 Apr 6.

United States Geological Survey, Upper Midwest Water Science Center, 8505 Research Way, Middleton, WI 53562, USA.

Urbanization can dramatically alter stormwater, both the quantity and quality, by engendering larger peak flows and through the introduction of contaminants into runoff. The current study builds on previous research that developed relationships between a suite of nonpoint source contaminants, known as trace organic contaminants (TOrCs), and hydrologic measurements for a series of storms (one site had 15 storms and the other had 19 storms) in Madison, WI, by creating statistical and deterministic models. Correlations and regressions were calculated between TOrC loads and hydrologic measurements for a series of storms for both a commercial site and a high-density residential site. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00489697193132
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http://dx.doi.org/10.1016/j.scitotenv.2019.03.327DOI Listing
April 2019
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Background levels of dioxin-like polychlorinated biphenyls (dlPCBs), polychlorinated, polybrominated and mixed halogenated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs, PBDD/Fs & PXDD/Fs) in sera of pregnant women in Accra, Ghana.

Sci Total Environ 2019 Apr 9;673:631-642. Epub 2019 Apr 9.

Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY 14260, USA. Electronic address:

Human exposure data on dioxins and dioxin-like compounds (DLCs) in Ghana are limited. Based on health risks associated with dioxins and DLCs, the impact of maternal body burdens on foetal exposure is significant. This is the first study that assesses polychlorinated, polybrominated and mixed halogenated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs, PBDD/Fs and PXDD/Fs), and dioxin-like polychlorinated biphenyls (dlPCBs) in sera of primiparous Ghanaians. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.04.060DOI Listing

Ecological policy benefit valuation based on public feedback: Forest ecosystem services in Wuyishan nature reserve, China.

Sci Total Environ 2019 Apr 8;673:622-630. Epub 2019 Apr 8.

Fujian Provincial Key Laboratory of Soil Environmental Health and Regulation, College of Resources and Environment, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.

The spontaneous expansion of tea cultivation has led to the degradation of forest ecosystem services in the Wuyishan national nature reserve (WNNR). In 2008, the local government put forward the policy of "returning tea to forests" (RTTF) to protect the forest ecosystem. However, in order to measure its effects over the past ten years, it is necessary to accurately quantify the economic benefits of this ecological policy. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.04.076DOI Listing
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