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Ability of volume measures of hydronephrosis to predict need for surgery and evaluate renal function in children with ureteropelvic junction obstruction.

Int J Urol 2021 Dec 6. Epub 2021 Dec 6.

Department of Urology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Objective: To explore the efficacy of quantitative renal volume measures on magnetic resonance urography images in predicting need for surgery among children with ureteropelvic junction obstruction and their ability to evaluate renal function.

Methods: A total of 88 cases of hydronephrosis in 50 patients were collected between 1 April 2018 and 31 March 2020, including 30 operated kidney and 58 unoperated kidney cases. Clinical data were collected, and quantitative analysis of magnetic resonance urography was performed. Read More

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December 2021

Dietary high-fructose reduces barrier proteins and activates mitogenic signalling in the testis of a rat model: Regulatory effects of kefir supplementation.

Andrologia 2021 Dec 6:e14342. Epub 2021 Dec 6.

Department of Biology, KO Science Faculty, Karamanoglu Mehmetbey University, Karaman, Turkey.

There are limited data on the influence of fructose rich diet on the male reproductive system. Kefir may have health beneficial effects, but its mechanism of action remains mostly unclear. Herein, we investigated the impact of dietary high fructose on tight junction proteins and mitogenic pathways in rat testis as well as their modulation by kefir supplementation. Read More

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December 2021

Conflict monitoring and attentional adjustment during binocular rivalry.

Eur J Neurosci 2021 Dec 6. Epub 2021 Dec 6.

Multisensory Research Group, Centre for Brain and Cognition, Universitat Pompeu Fabra, Barcelona, Spain.

To make sense of ambiguous and, at times, fragmentary sensory input, the brain must rely on a process of active interpretation. At any given moment, only one of several possible perceptual representations prevails in our conscious experience. Our hypothesis is that the competition between alternative representations induces a pattern of neural activation resembling cognitive conflict, eventually leading to fluctuations between different perceptual outcomes in the case of steep competition. Read More

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December 2021

The Evidence for Antimicrobial and Hard to Infect Regenerative Matrices.

Surg Technol Int 2021 Dec 6;39. Epub 2021 Dec 6.

Department of Surgery, Mount Sinai Healthcare System, Icahn School of Medicine, New York, NY.

Preparation of the wound bed is a key step in the use of cell- and tissue-based therapy (CTP). In particular, good pre-application debridement is an essential component of CTP. However, there are many situations in which the wound bed is not adequately debrided, including trauma, burn, and in cases of chronic wounds with significant biofilm. Read More

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December 2021

Erratum to: Cervical Single-Level Pincer Stenosis Causing Myelopathy: A Technical Note and Medium-term Results of a One-Session Microsurgical 360-Degree Treatment.

J Neurol Surg A Cent Eur Neurosurg 2021 Dec 6. Epub 2021 Dec 6.

Schoen Clinic Hamburg Eilbek, Academic Hospital of the Eppendorf University Medical Center - Clinic for Spine Surgery, Hamburg, Germany.

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December 2021

Definition of competence standards for optical diagnosis of diminutive colorectal polyps: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.

Endoscopy 2021 Dec 6. Epub 2021 Dec 6.

Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, location AMC, University of Amsterdam, Amsterdam, The Netherlands.

BACKGROUND : The European Society of Gastrointestinal Endoscopy (ESGE) has developed a core curriculum for high quality optical diagnosis training for practice across Europe. The development of easy-to-measure competence standards for optical diagnosis can optimize clinical decision-making in endoscopy. This manuscript represents an official Position Statement of the ESGE aiming to define simple, safe, and easy-to-measure competence standards for endoscopists and artificial intelligence systems performing optical diagnosis of diminutive colorectal polyps (1 - 5 mm). Read More

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December 2021

[Testicular Cancer Screening in Men Aged 16 Years and Older: IQWiG ThemenCheck Health Technology Assessment Report on Medical, Economic, Social, Ethical, Legal and Organisational Aspects].

Gesundheitswesen 2021 Dec 6. Epub 2021 Dec 6.

Dept. of Public Health, Health Services Research and Health Technology Assessment, UMIT - University for Health Sciences, Medical Informatics and Technology, Hall i.T, Österreich.

Background: Testicular cancer occurs mainly in young men between 25 and 45 years and is the most common cancer at this age. Possible testicular cancer early detection measures, clinical palpation and scrotal ultrasound (CUS) or testicular self-examination (TSE) in asymptomatic men aged 16 years and older, could perhaps avoid deaths and aggressive late therapies. Therefore, we investigated whether these measures have an additional benefit compared to the current situation. Read More

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December 2021

Regulation of the Effect of Physical Activity Through MicroRNAs in Breast Cancer.

Authors:
Bok Sil Hong

Int J Sports Med 2021 Dec 6. Epub 2021 Dec 6.

Cheju Halla University, Life Science Research Center, Department of Nursing, Jeju, Korea (the Republic of).

Physical activity and exercise can induce beneficial molecular and biological regulations that have been associated with an incidence of various diseases, including breast cancer. Recent studies demonstrated that the potential links between physical activity-induced circulating microRNAs (miRNAs) and cancer risk and progression. Here, we investigated whether altered miRNAs by exercise could influence breast cancer progression. Read More

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December 2021

Comparison of a Cancer Family History Collection and Risk Assessment Tool - ItRunsInMyFamily - with Risk Assessment by Health-Care Professionals.

Public Health Genomics 2021 Dec 6:1-9. Epub 2021 Dec 6.

Department of Human Genetics, Emory University, Atlanta, Georgia, USA.

Introduction: Primary care providers (PCPs) and oncologists lack time and training to appropriately identify patients at increased risk for hereditary cancer using family health history (FHx) and clinical practice guideline (CPG) criteria. We built a tool, "ItRunsInMyFamily" (ItRuns) that automates FHx collection and risk assessment using CPGs. The purpose of this study was to evaluate ItRuns by measuring the level of concordance in referral patterns for genetic counseling/testing (GC/GT) between the CPGs as applied by the tool and genetic counselors (GCs), in comparison to oncologists and PCPs. Read More

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December 2021

Treatment of Sleep Apnea with Positive Airway Pressure and Its Association with Diastolic Dysfunction: A Systematic Review and Meta-Analysis.

Respiration 2021 Dec 6:1-11. Epub 2021 Dec 6.

Cardiology Department, SUNY Downstate, Brooklyn, New York, USA.

Background: This meta-analysis assessed the effect of long-term (>6 weeks) noninvasive positive airway pressure (PAP) on diastolic function in patients with obstructive sleep apnea (OSA).

Methods: We searched the databases for randomized clinical trials including Ovid MEDLINE, Ovid Embase Scopus, Web of Science, Google Scholar, and EBSCO CINAHL from inception up to December 20, 2019. The search was not restricted to time, publication status, or language. Read More

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December 2021

Effectiveness of Emollients in the Prevention of Atopic Dermatitis in Infants: A Meta-Analysis.

Dermatology 2021 Dec 6:1-6. Epub 2021 Dec 6.

Department of Plastic Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Background: Atopic dermatitis (AD) is a chronic skin disease characterized by dry skin, severe itching, inflammation and impaired quality of life. Moisturizing is an integral part of treatment for AD, but its potential for prevention of AD is unclear.

Objective: To evaluate whether the early use of emollients in infancy can prevent later development of AD. Read More

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December 2021

School Sanitation-Related Psychosocial Stressors among Nigerian Students.

Am J Trop Med Hyg 2021 Dec 6. Epub 2021 Dec 6.

Department of Environmental Health Sciences, Faculty of Public Health, University of Ibadan, Ibadan, Nigeria.

Psychosocial stressors are indicative of challenges associated with the social and environmental conditions an individual is subjected to. In a bid to clearly understand the present gaps in school sanitation, this cross-sectional study aimed to identify the sanitation-related psychosocial stressors experienced by students in a Nigerian peri-urban community and their associated impacts. A three-stage sampling technique was used to select 400 students from 10 schools. Read More

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December 2021

Implementation Science to Improve Tobacco Cessation Services in Oncology Care.

Authors:

J Natl Compr Canc Netw 2021 Nov;19(Suppl_1):S12-S15

Every patient with cancer deserves access to evidence-based tobacco cessation interventions as part of their routine oncology care. The NCI Cancer Moonshot funded the Cancer Center Cessation Initiative (C3I) to help establish and/or expand tobacco treatment programs at 52 NCI-designated Cancer Centers. Although this initiative has broadened the availability of tobacco treatment services across US cancer centers, the reach and utilization of these services remains low among patients. Read More

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November 2021

Olive oil consumption is associated with a lower risk of cardiovascular disease and stroke.

Clin Nutr 2021 Nov 15;41(1):122-130. Epub 2021 Nov 15.

IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain; Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid-IdiPaz, Madrid, Spain; CIBERESP (CIBER of Epidemiology and Public Health), Madrid, Spain. Electronic address:

Background & Aims: The specific association of olive oil consumption with coronary heart disease (CHD) or stroke has not been totally established.

Objective: to examine whether olive oil consumption is associated with subclinical atherosclerosis, the risk of total cardiovascular disease (CVD), CHD, and stroke.

Methods: Three cohorts were included: AWHS (2318 men), SUN Project (18,266 men and women), and EPIC-Spain (39,393 men and women). Read More

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November 2021

Reactive oxygen species formation driven by acidophiles mediated pyrite oxidation and its potential role on 2,4-dichlorophenol transformation.

J Hazard Mater 2021 Nov 23;425:127833. Epub 2021 Nov 23.

School of Minerals Processing and Bioengineering, Key Laboratory of Biometallurgy of Ministry of Education, Central South University, Changsha 410083, China. Electronic address:

Researches of reactive oxygen species (ROS) generation from pyrite oxidation and its impact on contaminants transformation has been constrained to abiotic conditions. However, pyrite oxidation by acidophiles is widespread in acidic environments. The potential role of these microorganisms on pyrite-induced ROS formation and pollutants processing is not understood well. Read More

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November 2021

Understanding the effect of nonmetallic impurities in regenerated cathode materials for lithium-ion battery recycling by tracking down impurity elements.

J Hazard Mater 2021 Nov 26;425:127907. Epub 2021 Nov 26.

Department of Energy & Mineral Resources Engineering, Sejong University, Seoul 05006, Republic of Korea. Electronic address:

The regeneration of cathode materials would be the highest value-added direction in lithium-ion battery (LIB) recycling research. Li[NiMnCo]O (NMC) is regenerated from actual industrial scale LIB leachate and purified leachate to investigate the precipitation behavior of impurities, which include potentially toxic elements, such as F, Cl, and S. Regenerated precursors from the actual leachate, purified precursors, and a control sample are synthesized using the hydroxide co-precipitation method. Read More

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November 2021

Many heads are more utilitarian than one.

Cognition 2021 Dec 3;220:104965. Epub 2021 Dec 3.

Department of General Psychology and Education, Ludwig Maximillian's University, Munich, Germany; Centre for Adaptive Rationality, Max Planck Institute for Human Development, Berlin, Germany; Department of Psychology, Royal Holloway University of London, Egham, Surrey, London, UK.

Moral judgments have a very prominent social nature, and in everyday life, they are continually shaped by discussions with others. Psychological investigations of these judgments, however, have rarely addressed the impact of social interactions. To examine the role of social interaction on moral judgments within small groups, we had groups of 4 to 5 participants judge moral dilemmas first individually and privately, then collectively and interactively, and finally individually a second time. Read More

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December 2021

Chiral inversion of 2-arylpropionoic acid (2-APA) enantiomers during simulated biological wastewater treatment.

Water Res 2021 Nov 16;209:117871. Epub 2021 Nov 16.

Water Research Centre, School of Civil and Environmental Engineering, University of New South Wales, NSW 2052, Australia. Electronic address:

This study examined the removal and enantio‑specific fate of a suite of eleven chiral 2-arylpropionic acids (2-APAs) during biological wastewater treatment simulated in a laboratory-scale membrane bioreactor (MBR). Using pure (R)- and (S)- enantiomers in the MBR influent, chiral inversion was determined through the increase in the concentration of the non-dominant enantiomer and changes in the enantiomeric fraction (EF) between the two enantiomers during the treatment process. Effective (>90%) and similar removal rates between (R)- and (S)- enantiomers were confirmed for eight 2-APAs. Read More

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November 2021

Reduced cathodic scale and enhanced electrochemical precipitation of Ca and Mg by a novel fenced cathode structure: Formation of strong alkaline microenvironment and favorable crystallization.

Water Res 2021 Nov 27;209:117893. Epub 2021 Nov 27.

State Key Laboratory of Pollution Control and Resources Reuse, College of Environmental Science & Engineering, Tongji University, Shanghai 200092, PR China. Electronic address:

Electrochemical precipitation is a promising technique for hardness abatement without the addition of external ions. However, the scale layer on cathode deteriorated the removal efficiency and limited the practical application. Herein, a fenced cathode structure was designed to prevent cathodic precipitation. Read More

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November 2021

Comparison of traditional and closed loop vagus nerve stimulation for treatment of pediatric drug-resistant epilepsy: A propensity-matched retrospective cohort study.

Seizure 2021 Nov 29;94:74-81. Epub 2021 Nov 29.

Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

Objective: For epilepsy patients with drug-resistant, unresectable epilepsy, vagus nerve stimulation (VNS) is an option for seizure control. Approximately 40-70% of patients will achieve ≥50% seizure reduction with VNS. New closed loop VNS models detect ictal tachycardia and responsively stimulate the vagus nerve. Read More

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November 2021

Systematic expression profiling of neuropathy-related aminoacyl-tRNA synthetases in zebrafish during development.

Biochem Biophys Res Commun 2021 Nov 29;587:92-98. Epub 2021 Nov 29.

Disease Target Structure Research Center, KRIBB, Daejeon, South Korea; KRIBB School, University of Science and Technology, Daejeon, South Korea; Dementia DTC R&D Convergence Program, KIST, Seoul, South Korea. Electronic address:

Aminoacyl tRNA synthetases (ARSs) are a group of proteins, acting as transporters to transfer and attach the appropriate amino acids onto their cognate tRNAs for translation. So far, 18 out of 20 cytoplasmic ARSs are reported to be connected to different neuropathy disorders with multi-organ defects that are often accompanied with developmental delays. Thus, it is important to understand functions and impacts of ARSs at the whole organism level. Read More

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November 2021

Genome-wide survey and functional analysis reveal TCF21 promotes chicken preadipocyte differentiation by directly upregulating HTR2A.

Biochem Biophys Res Commun 2021 Nov 30;587:131-138. Epub 2021 Nov 30.

Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Harbin, 150030, Heilongjiang, China; Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin, 150030, Heilongjiang, China; College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, Heilongjiang, China. Electronic address:

Background/aim: Previously, we showed that transcription factor 21 (TCF21) promotes chicken preadipocyte differentiation. However, the genome-wide TCF21 binding sites and its downstream target genes in chicken adipogenesis were unknown.

Methods: ChIP-Seq and RNA-Seq were used to screen candidate targets of TCF21. Read More

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November 2021

Diverse risk-avoidance behaviors in DISC1 mice are associated with different neuronal firing patterns in BLA neurons.

Biochem Biophys Res Commun 2021 Nov 29;587:107-112. Epub 2021 Nov 29.

Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055, China; University of Chinese of Academy of Sciences, Beijing, 100049, China. Electronic address:

It is very important to maintain normal levels of risk avoidance in daily life. We found that DISC1-N mice, which are a model for mental disorders, had a phenotype marked by a risk-avoidance impairment as measured in an open-field test (OFT). We used optogenetic methods to modulate glutamatergic neurons in the basolateral amygdala (BLA) in an attempt to rescue this risk-avoidance impairment. Read More

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November 2021

The role of bullying victimization in the pathway between autistic traits and psychotic experiences in adolescence: Data from the Tokyo Teen Cohort study.

Schizophr Res 2021 Dec 3;239:111-115. Epub 2021 Dec 3.

Research Center for Social Science & Medicine, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.

Autistic traits are associated with psychotic experiences in adolescence; however, the mechanisms underlying this relationship are not well understood. Prior research indicates that bullying victimization increases the risk of psychotic experiences in general adolescent populations, and autistic youth are at higher risk of being bullied than their non-autistic peers. Using longitudinal data from general population adolescents aged 10-14 in the Tokyo Teen Cohort study, we tested the hypothesis that bullying is responsible for the association between autistic traits and psychotic experiences in adolescence. Read More

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December 2021

Interactive effects of maintenance decay and interference on working memory updating in schizophrenia.

Schizophr Res 2021 Dec 3;239:103-110. Epub 2021 Dec 3.

Department of Psychology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, United States. Electronic address:

Background: Deficits in working memory have been identified as a core cognitive impairment in schizophrenia. Prior work has identified a unique pattern of rapidly decreasing accuracy following intact encoding and updating of a single visuospatial target in patients with schizophrenia. Understanding whether these deficits are related to disruption of working memory stores following retrieval or part of a broader maintenance dysfunction may help elucidate the specific subprocesses underlying working memory deficits in schizophrenia. Read More

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December 2021

Pathogenicity and molecular characterization of infectious bursal disease virus in China.

Poult Sci 2021 Oct 19;101(1):101502. Epub 2021 Oct 19.

Guangdong Provincial Animal Virus Vector Vaccine Engineering Technology Research Center, College of Animal Science, South China Agricultural University, Guangzhou, 510642, P.R. China.; Key Laboratory of Healthy Animal Husbandry and Environmental Control of Guangdong Province, Guangzhou, 510642, Guangdong, P.R. China.. Electronic address:

Infectious bursal disease virus (IBDV) caused an acute and highly contagious infectious disease, resulting in considerable economic losses in the world poultry industry. Although this disease was well-controlled under the widely use of commercial vaccines, the novel variant IBDV strain emerged due to the highly immunized-selection pressure in the field, posting new threats to poultry industry. Here, we reported the epidemic and pathogenicity of IBDV in Hubei Province from May to August 2020. Read More

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October 2021

Phytochemical control of poultry coccidiosis: a review.

Poult Sci 2021 Oct 14;101(1):101542. Epub 2021 Oct 14.

Poultry and Fish Diseases Department, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, Egypt.

Avian coccidiosis is a major parasitic disorder in chickens resulting from the intracellular apicomplexan protozoa Eimeria that target the intestinal tract leading to a devastating disease. Eimeria life cycle is complex and consists of intra- and extracellular stages inducing a potent inflammatory response that results in tissue damage associated with oxidative stress and lipid peroxidation, diarrheal hemorrhage, poor growth, increased susceptibility to other disease agents, and in severe cases, mortality. Various anticoccidial drugs and vaccines have been used to prevent and control this disorder; however, many drawbacks have been reported. Read More

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October 2021

Influence of rapeseed, canola meal and glucosinolate metabolite (AITC) as potential antimicrobials: effects on growth performance, and gut health in Salmonella Typhimurium challenged broiler chickens.

Poult Sci 2021 Oct 20;101(1):101551. Epub 2021 Oct 20.

Department of Poultry Science, University of Georgia, Athens, GA, 30602, USA. Electronic address:

Poultry is the major sources of foodborne salmonellosis. Antibiotic resistance and a surge in zoonotic diseases warrant the use of natural alternatives. Glucosinolates (GLs) are naturally occurring antimicrobial compounds in rapeseed and canola. Read More

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October 2021

Depression and generalised anxiety and associated factors among adults in Bhutan: Results of national cross-sectional survey in 2019.

Asian J Psychiatr 2021 Nov 29;67:102959. Epub 2021 Nov 29.

Department of Research Administration and Development, University of Limpopo, Polokwane, South Africa; Department of Psychology, College of Medical and Health Science, Asia University, Taichung, Taiwan. Electronic address:

The study aimed to evaluate the prevalence and correlates of major depressive disorder (MDD) and generalised anxiety disorder (GAD) in people 15 years in Bhutan in 2019. Cross-sectional data were analyzed from 5575 people (15-69 years) who participated in the 2019 Bhutan STEPS survey. The proportion of mild MDD was 12. Read More

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November 2021