291 results match your criteria Schweizerische Rundschau fuer Medizin Praxis = Revue suisse de medecine Praxis[Journal]


Use and inhalation technique of inhaled medication in patients with asthma and COPD: data from a randomized controlled trial.

Respir Res 2018 Dec 3;19(1):237. Epub 2018 Dec 3.

University Clinic of Medicine, Cantonal Hospital Baselland, Rheinstrasse 26, CH - 4410, Liestal, Switzerland.

Background: The burden of asthma and COPD among patients is high and people affected are frequently hospitalized due to exacerbations. There are numerous reasons for the lack of disease control in asthma and COPD patients. It is associated with non-adherence to guidelines on the part of the health care provider and with poor inhalation technique and/or non-adherence to the prescribed treatment plan by the patient. Read More

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http://dx.doi.org/10.1186/s12931-018-0936-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276152PMC
December 2018

Consent requirements for research with human tissue: Swiss ethics committee members disagree.

BMC Med Ethics 2018 Nov 26;19(1):93. Epub 2018 Nov 26.

Institute for Biomedical Ethics, Bernoullistrasse 28, 4055, Basel, Switzerland.

Background: In Switzerland, research with identifiable human tissue samples, and/or its accompanying data, must be approved by a research ethics committee (REC) before it can be allowed to take place. However, as the demand for such tissue has rapidly increased in recent years, and biobanks have been created to meet these needs, committees have had to deal with a growing number of such demands. Detailed instructions for evaluating every kind of tissue request are scarce. Read More

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http://dx.doi.org/10.1186/s12910-018-0331-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260886PMC
November 2018

Rationale and methods of an observational study to support the design of a nationwide surgical registry: the MIDAS study.

Swiss Med Wkly 2018 11 18;148:w14680. Epub 2018 Nov 18.

Department of Orthopaedics and Traumatology, University Hospital Basel, Switzerland.

BACKGROUND Surgical registries are becoming increasingly popular. In addition, Swiss legislation requires data on therapeutic outcome quality. The Swiss Association of Surgeons (Schweizerische Gesellschaft Chirurgie, SGC-SCC) has already agreed on a first minimum data set. Read More

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http://dx.doi.org/10.4414/smw.2018.14680DOI Listing
November 2018
4 Reads

Anticipation of food intake induces phosphorylation switch to regulate basolateral amino acid transporter LAT4 (SLC43A2) function.

J Physiol 2018 Oct 31. Epub 2018 Oct 31.

Institute of Physiology and Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland.

Key Points: Amino acid absorption requires luminal uptake into and subsequent basolateral efflux out of epithelial cells, with the latter step being critical to regulate the intracellular concentration of the amino acids. The basolateral essential neutral amino acid uniporter LAT4 (SLC43A2) has been suggested to drive the net efflux of non-essential and cationic amino acids via parallel amino acid antiporters by recycling some of their substrates; its deletion has been shown to cause defective postnatal growth and death in mice. Here we test the regulatory function of LAT4 phosphorylation sites by mimicking their phosphorylated and dephosphorylated states in Xenopus laevis oocytes and show that dephosphorylation of S274 and phosphorylation of S297 increase LAT4 membrane localization and function. Read More

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http://doi.wiley.com/10.1113/JP276714
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http://dx.doi.org/10.1113/JP276714DOI Listing
October 2018
1 Read

Development of a Novel Human Cell-Derived Tissue-Engineered Heart Valve for Transcatheter Aortic Valve Replacement: an In Vitro and In Vivo Feasibility Study.

J Cardiovasc Transl Res 2018 Dec 13;11(6):470-482. Epub 2018 Aug 13.

Institute for Regenerative Medicine (IREM), University of Zurich, Center for Therapy Development/GMP, Zurich, Switzerland.

Transcatheter aortic valve replacement (TAVR) is being extended to younger patients. However, TAVR-compatible bioprostheses are based on xenogeneic materials with limited durability. Off-the-shelf tissue-engineered heart valves (TEHVs) with remodeling capacity may overcome the shortcomings of current TAVR devices. Read More

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http://dx.doi.org/10.1007/s12265-018-9821-1DOI Listing
December 2018

Specific synaptic input strengths determine the computational properties of excitation-inhibition integration in a sound localization circuit.

J Physiol 2018 Oct 28;596(20):4945-4967. Epub 2018 Aug 28.

Laboratory of Synaptic Mechanisms, Brain Mind Institute, School of Life Science, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

Key Points: During the computation of sound localization, neurons of the lateral superior olive (LSO) integrate synaptic excitation arising from the ipsilateral ear with inhibition from the contralateral ear. We characterized the functional connectivity of the inhibitory and excitatory inputs onto LSO neurons in terms of unitary synaptic strength and convergence. Unitary IPSCs can generate large conductances, although their strength varies over a 10-fold range in a given recording. Read More

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http://dx.doi.org/10.1113/JP276012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187026PMC
October 2018
14 Reads

PDGF-BB regulates splitting angiogenesis in skeletal muscle by limiting VEGF-induced endothelial proliferation.

Angiogenesis 2018 Nov 16;21(4):883-900. Epub 2018 Jul 16.

Department of Biomedicine, Basel University Hospital, University of Basel, Hebelstrasse 20, 4031, Basel, Switzerland.

VEGF induces normal or aberrant angiogenesis depending on its dose in the microenvironment around each producing cell in vivo. This transition depends on the balance between VEGF-induced endothelial stimulation and PDGF-BB-mediated pericyte recruitment, and co-expression of PDGF-BB normalizes aberrant angiogenesis despite high VEGF doses. We recently found that VEGF over-expression induces angiogenesis in skeletal muscle through an initial circumferential vascular enlargement followed by longitudinal splitting, rather than sprouting. Read More

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http://dx.doi.org/10.1007/s10456-018-9634-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208885PMC
November 2018
2 Reads

Obstruction of ventricular Ca -dependent arrhythmogenicity by inositol 1,4,5-trisphosphate-triggered sarcoplasmic reticulum Ca release.

J Physiol 2018 Sep 7;596(18):4323-4340. Epub 2018 Aug 7.

Department of Physiology, University of Bern, Buehlplatz 5, CH-3012, Bern, Switzerland.

Key Points: Augmented inositol 1,4,5-trisphosphate (IP ) receptor (IP R2) expression has been linked to a variety of cardiac pathologies. Although cardiac IP R2 function has been in the focus of research for some time, a detailed understanding of its potential role in ventricular myocyte excitation-contraction coupling under pathophysiological conditions remains elusive. The present study focuses on mechanisms of IP R2-mediated sarcoplasmic reticulum (SR)-Ca release in ventricular excitation-contraction coupling under IP R2-overexpressing conditions by studying intracellular Ca events. Read More

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http://doi.wiley.com/10.1113/JP276319
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http://dx.doi.org/10.1113/JP276319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138286PMC
September 2018
11 Reads

Evaluation of a Fluorescence-aided Identification Technique (FIT) for removal of composite bonded trauma splints.

Dent Traumatol 2018 Oct 24;34(5):353-359. Epub 2018 Aug 24.

Department of Periodontology, Endodontology and Cariology, Center of Dental Traumatology, University Center for Dental Medicine, University of Basel, Basel, Switzerland.

Background/aim: Accurate removal of composite bonded titanium trauma splints (TTS) can be challenging. The aim of this study was to evaluate a Fluorescence-aided Identification Technique (FIT) compared with a conventional light source (CT) for removal of trauma splints regarding loss of tooth substance, residual composite, and time taken.

Materials And Methods: Twenty maxillary models with six bovine teeth (13 - 23) were fabricated. Read More

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http://doi.wiley.com/10.1111/edt.12425
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http://dx.doi.org/10.1111/edt.12425DOI Listing
October 2018
7 Reads

Solidarity and cost management: Swiss citizens' reasons for priorities regarding health insurance coverage.

Health Expect 2018 Oct 14;21(5):858-869. Epub 2018 Apr 14.

Institute for Ethics, History, and the Humanities, Geneva University Medical School, Geneva, Switzerland.

Context: Approaches to priority-setting for scarce resources have shifted to public deliberation as trade-offs become more difficult. We report results of a qualitative analysis of public deliberation in Switzerland, a country with high health-care costs, an individual health insurance mandate and a strong tradition of direct democracy with frequent votes related to health care.

Methods: We adapted the Choosing Healthplans All Together (CHAT) tool, an exercise developed to transform complex health-care allocation decisions into easily understandable choices, for use in Switzerland. Read More

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http://dx.doi.org/10.1111/hex.12680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186533PMC
October 2018
1 Read

Recommendations of Swiss Memory Clinics for the Diagnosis of Dementia

Praxis (Bern 1994) 2018 04;107(8):435-451

1 Swiss Memory Clinics.

The early diagnosis of subjectively perceived or externally anamnestically observed cognitive impairments is essential for proving neurodegenerative diseases or excluding treatable causes such as internal, neurological or psychiatric disorders. Only in this way is early treatment made possible. As part of the project 3. Read More

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http://dx.doi.org/10.1024/1661-8157/a002948DOI Listing
April 2018
13 Reads

Study design and baseline characteristics of a combined educational and environmental intervention trial to lower sodium intake in Swiss employees.

BMC Public Health 2018 Apr 2;18(1):421. Epub 2018 Apr 2.

Department of Clinical Medicine & Surgery, Federico II University of Naples Medical School, via S. Pansini 5, 80131, Naples, Italy.

Background: Blood pressure is a primary cardiovascular disease risk factor. Population-wide governmental strategies aim to reduce lifestyle and dietary risk factors for hypertension, one of which is an unbalanced diet with high sodium and low potassium intakes. Nutrition interventions in the workplace are considered a promising approach in encouraging health-promoting behaviors. Read More

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https://bmcpublichealth.biomedcentral.com/articles/10.1186/s
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http://dx.doi.org/10.1186/s12889-018-5366-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879608PMC
April 2018
5 Reads

The Quest for Clarity in Research Integrity: A Conceptual Schema.

Authors:
David Shaw

Sci Eng Ethics 2018 Mar 28. Epub 2018 Mar 28.

Institute for Biomedical Ethics, University of Basel, Bernoullistrasse 28, 4056, Basel, Switzerland.

Researchers often refer to "research integrity", "scientific integrity", "research misconduct", "scientific misconduct" and "research ethics". However, they may use some of these terms interchangeably despite conceptual distinctions. The aim of this paper is to clarify what is signified by several key terms related to research integrity, and to suggest clearer conceptual delineation between them. Read More

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http://dx.doi.org/10.1007/s11948-018-0052-2DOI Listing
March 2018
2 Reads

Complementary Medicine Research: Auch ein Geschichtsbuch der SMGP.

Authors:
Beat Meier

Complement Med Res 2018;25(1):7-8. Epub 2018 Feb 20.

Schweizerische Medizinische Gesellschaft für Phytotherapie und Zürcher Hochschule für angewandte Wissenschaften, Fachgruppe für Phytopharmazie und Naturstoffe, Wädenswil, Schweiz.

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http://dx.doi.org/10.1159/000487416DOI Listing
February 2018

Empfehlungen für Diagnostik und Therapie der Depression im Alter.

Praxis (Bern 1994) 2018 Jan;107(3):127-144

1 Schweizerische Gesellschaft für Alterspsychiatrie und Alterspsychotherapie (SGAP).

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http://dx.doi.org/10.1024/1661-8157/a002883DOI Listing
January 2018
5 Reads

Gifttiere und Tiermedizin in Antike und Gegenwart.

Authors:
W Sackmann

Schweiz Arch Tierheilkd 2018 Jan;160(1):61-63

Schweizerische Vereinigung für Geschichte der Veterinärmedizin.

Introduction: The veterinary manuals by Vegetius, Pelagonius and Chiron Kentauros, all three dating from the 4th century, contain remarks about livestock being poisoned by animal venoms. It is suggested, that livestock bitten by contaminated shrews, reptiles, scorpions, beetles and spiders shows signs of poisoning. The authors present various possible therapies for the sick livestock. Read More

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http://dx.doi.org/10.17236/sat00145DOI Listing
January 2018
2 Reads

[Leonhard Riedmüller: Swiss public enemy or pawn sacrifice?]

Authors:
A Pospischil

Schweiz Arch Tierheilkd 2018 Jan;160(1):57-60

Schweizerische Vereinigung für Geschichte der Veterinärmedizin.

Introduction: On June 9, 1945 the Zurich cantonal government issued the lifetime deportation from Switzerland for Prof. Dr. med. Read More

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http://dx.doi.org/10.17236/sat00144DOI Listing
January 2018

[Animal ethics in the 19th century and Swiss animal protection law].

Authors:
I Bloch

Schweiz Arch Tierheilkd 2018 Jan;160(1):51-56

Schweizerische Vereinigung für Geschichte der Veterinärmedizin.

Introduction: The development of animal ethics and animal rights from the antiquity up to modern times is described. The relationship of humans to animals was primarily based on fear and animal cult, developed by the domestication to a partnership. The philosophers of the early modern age denied the animals the reason, what was disadvantageous to the position of the animals in the society and the behavior of humans to the animals. Read More

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http://dx.doi.org/10.17236/sat00143DOI Listing
January 2018

[The Swiss border veterinary service in the 20th century].

Authors:
J Schluep

Schweiz Arch Tierheilkd 2018 Jan;160(1):43-50

Schweizerische Vereinigung für Geschichte der Veterinärmedizin.

Introduction: The first animal disease act of Switzerland was released in 1872. Its revision in 1886 brought the basis for establishing a border veterinary inspection service. This service was first reporting to the federal Ministry of Agriculture; after 1914, the newly created Federal Veterinary Office became responsible for it. Read More

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http://dx.doi.org/10.17236/sat00142DOI Listing
January 2018

[The 1935 veterinary agreements of the League of the Nations: A vision of a united veterinary Europe].

Authors:
S Häsler

Schweiz Arch Tierheilkd 2018 Jan;160(1):37-42

Schweizerische Vereinigung für Geschichte der Veterinärmedizin.

Introduction: A group of leading veterinary experts engaged by the league of the Nations created three new Veterinary Conventions focusing at consequently controlling the import, export and transit of animals and animal products. The aim was on one hand to facilitate trade and on the other hand to make sure that livestock epidemic laws were respected. The outbreak of war prevented the laws from coming into effect. Read More

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http://dx.doi.org/10.17236/sat00141DOI Listing
January 2018

Development of a monitoring instrument to assess the performance of the Swiss primary care system.

BMC Health Serv Res 2017 Nov 29;17(1):789. Epub 2017 Nov 29.

Department of Ambulatory Care and Community Medicine, University of Lausanne, Bugnon 44, 1011 Lausanne, Lausanne, Switzerland.

Background: The Swiss health system is customer-driven with fee-for-service paiement scheme and universal coverage. It is highly performing but expensive and health information systems are scarcely implemented. The Swiss Primary Care Active Monitoring (SPAM) program aims to develop an instrument able to describe the performance and effectiveness of the Swiss PC system. Read More

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http://dx.doi.org/10.1186/s12913-017-2696-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707782PMC
November 2017
6 Reads

Time versus energy minimization migration strategy varies with body size and season in long-distance migratory shorebirds.

Mov Ecol 2017 7;5:23. Epub 2017 Nov 7.

Centre for Integrative Ecology, School of Life and Environmental Sciences, Deakin University, Geelong, Australia.

Background: Migrants have been hypothesised to use different migration strategies between seasons: a time-minimization strategy during their pre-breeding migration towards the breeding grounds and an energy-minimization strategy during their post-breeding migration towards the wintering grounds. Besides season, we propose body size as a key factor in shaping migratory behaviour. Specifically, given that body size is expected to correlate negatively with maximum migration speed and that large birds tend to use more time to complete their annual life-history events (such as moult, breeding and migration), we hypothesise that large-sized species are time stressed all year round. Read More

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http://movementecologyjournal.biomedcentral.com/articles/10.
Publisher Site
http://dx.doi.org/10.1186/s40462-017-0114-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674797PMC
November 2017
6 Reads

[AntibioticScout.ch: A decision supporting tool for antimicrobial stewardship: application to companion animal medicine].

Schweiz Arch Tierheilkd 2017 Oct;159(10):525-533

Institut für Veterinärpharmakologie und -toxikologie, Universität Zürich.

Introduction: Bacterial resistances to antimicrobial drugs pose serious public health challenges. The observed increase of resistances is attributed to the uncontrolled, massive and often unnecessary administration of antibiotics both in human and veterinary medicine. To support the responsible use of antimicrobials in animals and help veterinarians selecting the most suitable antimicrobial drugs, we developed the AntibioticScout. Read More

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http://dx.doi.org/10.17236/sat00129DOI Listing
October 2017

Die Versorgung von Schwerstverletzten: von der Unfallstelle bis zur Notaufnahme.

Praxis (Bern 1994) 2017 Jul;106(15):825-828

3 Schweizerische Rettungsflugwacht (Rega), Zürich-Flughafen.

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http://dx.doi.org/10.1024/1661-8157/a002742DOI Listing
July 2017
5 Reads

Improving the Management of Psoriatic Arthritis and Axial Spondyloarthritis: Roundtable Discussions with Healthcare Professionals and Patients.

Rheumatol Ther 2017 Dec 9;4(2):219-231. Epub 2017 Jun 9.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

Psoriatic arthritis (PsA) and axial spondyloarthritis (AxSpA) are both chronic, inflammatory conditions that result in a substantial burden of disease and reduced quality of life for patients. Patient involvement in developing optimal disease management strategies, including defining appropriate goals, therapies, and treatment options, as well as in setting policy priorities and agendas, is key. A working group of patient organization representatives and rheumatologists explored what patients consider to be unmet needs, important treatment gaps, and future priorities in PsA and AxSpA management. Read More

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http://dx.doi.org/10.1007/s40744-017-0066-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696278PMC
December 2017
52 Reads

Wie können wir die Lebensqualität von Patienten mit COPD verbessern?

Authors:
Otto Brändli

Praxis (Bern 1994) 2017;106(11):579-582

1 Schweizerische Lungenstiftung, Wald.

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http://dx.doi.org/10.1024/1661-8157/a002691DOI Listing
August 2017
5 Reads

Erratum to: Good neurological outcome after primary accidental hypothermia presenting with asystole.

Anaesthesist 2017 04;66(4):293-294

Abteilung für Anästhesiologie, Schmerztherapie und Rettungsmedizin, Ospidal - Gesundheitszentrum Unterengadin, Via Ospidal, 7550, Scuol, Switzerland.

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http://dx.doi.org/10.1007/s00101-017-0292-6DOI Listing
April 2017
6 Reads

Energy metabolism during endurance flight and the post-flight recovery phase.

J Comp Physiol A Neuroethol Sens Neural Behav Physiol 2017 Jul 21;203(6-7):431-438. Epub 2017 Feb 21.

Schweizerische Vogelwarte, Seerose 1, 6204, Sempach, Switzerland.

Migrating birds are known to fly non-stop for thousands of kilometres without food or water intake and at a high metabolic rate thereby relying on energy stores which were built up preceding a flight bout. Hence, from a physiological point of view the metabolism of a migrant has to switch between an active fasting phase during flight and a fuelling phase during stopover. To meet the energetic and water requirements of endurance flight, migratory birds have to store an optimal fuel composition and they have to be able to quickly mobilize and deliver sufficient energy to the working flight muscles. Read More

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http://dx.doi.org/10.1007/s00359-017-1150-3DOI Listing

Good neurological outcome after accidental hyopthermia presenting with asytole.

Anaesthesist 2017 Mar 7;66(3):186-188. Epub 2017 Feb 7.

Abteilung für Anästhesiologie, Schmerztherapie und Rettungsmedizin, Ospidal - Gesundheitszentrum Unterengadin, Via Ospidal, 7550, Scuol, Switzerland.

A 43-year-old woman became exhausted and fainted on descent at 1127 MAMSL altitude and snowfall. A rescue team diagnosed asystole. With manual cardiopulmonary resuscitation (CPR) she was transported to the next extracorporeal life support (ECLS) center. Read More

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http://dx.doi.org/10.1007/s00101-017-0271-yDOI Listing
March 2017
1 Read

[Statistics of the activities of a veterinarian from the Canton of Neuchâtel from the 19th century].

Authors:
A Rutti

Schweiz Arch Tierheilkd 2017 01;159(1):65-70

Schweizerische Vereinigung für Geschichte der Veterinärmedizin.

Introduction: Abraham Buehler wrote a statistical sketch of his activity as a practitioner during the years 1855 to 1861 in "Les Verrières" in the Swiss Canton of Neuchâtel. He included charts relating to diseases observed in different species such as horses, cows, goats, sheep, pigs and dogs. He described the evolution of the foot and mouth epidemic in the region during the years 1855 and 1856. Read More

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http://dx.doi.org/10.17236/sat00103DOI Listing
January 2017

[Fighting malpractice and uncooperative behaviour in the "Swiss Archive for Veterinary Science" 1816-2016].

Authors:
U Jenny

Schweiz Arch Tierheilkd 2017 01;159(1):59-64

Schweizerische Vereinigung für Geschichte der Veterinärmedizin.

Introduction: Already back in the 18th century, the treatment of sick animals was reserved for licensed veterinarians in most Cantons. Various articles from the first 100 years of the Swiss Archives for Veterinary Science show that over and over again unqualified people offered their services to livestock owners. A detailed article from the year 1843 on the resulting situation in the Canton of Berne and the need for corrective measures are presented. Read More

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http://dx.doi.org/10.17236/sat00102DOI Listing
January 2017

[Historic treasures of Swiss horse breeding].

Authors:
H Meier

Schweiz Arch Tierheilkd 2017 01;159(1):51-57

Schweizerische Vereinigung für Geschichte der Veterinärmedizin.

Introduction: Both a mandate of the Bernese Government (1705) and statements in the Georgica Helvetica of 1706 prove that Swiss horse breeding was lucrative and of good quality at that time. However, the political turmoil at the transition from the 18th to 19th century and excessive sales to France and Italy led to a severe drop in quantity as well in quality. The exhibition of horses in Aarau in 1865 showed a wretched state of the material. Read More

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http://dx.doi.org/10.17236/sat00101DOI Listing
January 2017

Muscular activity may improve in edentulous patients after implant treatment.

Evid Based Dent 2016 12;17(4):119-120

Faculty of Dentistry, McGill, Montreal, Canada.

Data sourcesMedline via Pubmed and the Cochrane Library were searched from January 1980 to September 2013. This was complemented by a manual search of the magazines Deutsche Zahnaerztliche Zeitung, Quintessenz, Zeitschrift für Zahnärztliche Implantologie, Schweizerische Monatszeitschrift and Implantologie. Additionally, the list of reference s of all selected full-text articles and related reviews were further scrutinised for potential included studies in English or German. Read More

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http://dx.doi.org/10.1038/sj.ebd.6401207DOI Listing
December 2016
2 Reads

Digital 3D reconstructions using histological serial sections of lung tissue including the alveolar capillary network.

Am J Physiol Lung Cell Mol Physiol 2017 Feb 2;312(2):L243-L257. Epub 2016 Dec 2.

Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany.

Digital 3D reconstructions using histological serial sections of lung tissue including the alveolar capillary network. 312: L243-L257, 2017. First published December 2, 2016; doi:10. Read More

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http://dx.doi.org/10.1152/ajplung.00326.2016DOI Listing
February 2017
15 Reads

[Not Available].

Praxis (Bern 1994) 2016 Aug;105(16):941-52

9 Centre Hospitalier Universitaire Vaudois (CHUV).

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http://dx.doi.org/10.1024/1661-8157/a002433DOI Listing
August 2016
17 Reads

[Not Available].

Authors:
Philip Bruggmann

Praxis (Bern 1994) 2016 Jul;105(15):885-9

1 Arud Zentren für Suchtmedizin, Zürich.

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http://dx.doi.org/10.1024/1661-8157/a002424DOI Listing
July 2016
1 Read

[Therapy of bone metastases with radium-223. German guidelines].

Nuklearmedizin 2016 Sep 15;55(5):177-86. Epub 2016 Jul 15.

Dr. Thorsten Pöppel, Universitätsklinikum Essen, Klinik für Nuklearmedizin, Hufelandstr. 55, 45122 Essen,

This document describes the guideline for therapy of bone metastases with radium-223 ((223)Ra) published by the Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften in Germany (AWMF) under the auspices of the Deutsche Gesellschaft für Nuklearmedizin (DGN), Östereichische Gesellschaft für Nuklearmedizin (OGN), and Schweizerische Gesellschaft für Nuklearmedizin (SGNM). This guidance is based on an interdisciplinary consensus. These recommendations are a prerequisite for the quality management in the treatment of patients with bone metastases from prostate cancer using (223)Ra. Read More

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http://dx.doi.org/10.3413/Nukmed-2016050001DOI Listing
September 2016
13 Reads

Physical activity prescription: a critical opportunity to address a modifiable risk factor for the prevention and management of chronic disease: a position statement by the Canadian Academy of Sport and Exercise Medicine.

Br J Sports Med 2016 Sep 22;50(18):1109-14. Epub 2016 Jun 22.

Dip. Sport Med (CASEM), University of Ottawa, Ontario, Canada.

Non-communicable disease is a leading threat to global health. Physical inactivity is a large contributor to this problem; in fact, the WHO ranks it as the fourth leading risk factor for overall morbidity and mortality worldwide. In Canada, at least 4 of 5 adults do not meet the Canadian Physical Activity Guidelines of 150 min of moderate-to-vigorous physical activity per week. Read More

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http://dx.doi.org/10.1136/bjsports-2016-096291DOI Listing
September 2016
7 Reads

A systematic review and meta-analysis on the influence of biological implant surface coatings on periimplant bone formation.

J Biomed Mater Res A 2016 11 4;104(11):2898-910. Epub 2016 Jul 4.

Clinic of Cranio-Maxillofacial and Oral Surgery, University of Zurich, University Hospital Zurich, Plattenstr. 11, CH-8032 Zurich, Switzerland.

This systematic review and meta-analysis evaluated the influence of biological implant surface coatings on periimplant bone formation in comparison to an uncoated titanium reference surface in experimental large animal models. The analysis was structured according to the PRISMA criteriae. Of the1077 studies, 30 studies met the inclusion criteriae. Read More

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http://dx.doi.org/10.1002/jbm.a.35805DOI Listing
November 2016
3 Reads

Surgical Interventions on the External Female Genitalia in Switzerland.

Geburtshilfe Frauenheilkd 2016 Apr;76(4):396-402

Praxis Dr. Gsell, Zürich, Switzerland; Section Gender Studies, Universität Zürich. Asien-Orient-Institut, Zürich, Switzerland.

With this online survey, data on surgical interventions on the external female genitalia in Switzerland, differentiated according to functional, aesthetic and psychological reasons, were collected for the first time. In September 2013 an invitation to respond to the quantitative and qualitative questions of a comprehensive, anonymous online survey was sent by e-mail to a total of 1740 members of the Swiss Society of Gynaecology and Obstetrics (Schweizerische Gesellschaft für Gynäkologie und Geburtshilfe) and the Swiss Society of Plastic Surgery (Schweizerische Gesellschaft für Plastische Chirurgie). Follow-up enquiries were made in June 2014. Read More

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http://dx.doi.org/10.1055/s-0041-111171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846410PMC

Accomplishments of Heinz Baumberger PhD: a remarkable patient with ankylosing spondylitis for 72 years.

Authors:
Muhammad A Khan

Clin Rheumatol 2016 Jun 25;35(6):1637-41. Epub 2016 Apr 25.

Case Western Reserve University, Cleveland, OH, USA.

This is the story of a remarkable Swiss patient-Heinz Baumberger, PhD-who was born in 1931 and has suffered from ankylosing spondylitis (AS) since 1943. He has survived many manifestations and co-morbid conditions associated with his disease and its treatment. These include severe episodes of acute anterior uveitis, osteoporosis with fragility fractures, and also post-traumatic spinal fractures on three different occasions. Read More

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http://dx.doi.org/10.1007/s10067-016-3259-0DOI Listing
June 2016
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Gains and losses on the road to understanding Alzheimer's disease.

Authors:
Uwe Konietzko

Swiss Med Wkly 2015 23;145:w14233. Epub 2015 Dec 23.

Division of Psychiatry Research, University of Zurich.

Alzheimer's disease (AD) is a neurodegenerative disorder and the most common cause for dementia, which affects approximately 120 thousand people in Switzerland and 35 million worldwide. Aging is a major risk factor for developing AD and thus, as our societies are growing older, we face great challenges to find treatment strategies. The disease is characterised by loss of memory, deposition of extracellular amyloid plaques containing Aβ peptides and intraneuronal tangles of the tau protein. Read More

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http://dx.doi.org/10.4414/smw.2015.14233DOI Listing
September 2016
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Can We Reduce Negative Blood Cultures With Clinical Scores and Blood Markers? Results From an Observational Cohort Study.

Medicine (Baltimore) 2015 Dec;94(49):e2264

From the University Department of Internal Medicine, Medical Faculty of the University of Basel, Kantonsspital Aarau, Switzerland (SL, NK, DS, ACR, AK, SF, LF, BM, PS); Asclepius Medical Communications LLC, Ridgewood, NJ, USA (PK); University Clinic of Infectious Diseases, University Hospital Bern (SH); Institute of Psychology, University of Bern (LF); Department of Laboratory Medicine, Kantonsspital (AH); and Clinic of Infectious Diseases, Kantonsspital Aarau, Switzerland (CAF).

Only a small proportion of blood cultures routinely performed in emergency department (ED) patients is positive. Multiple clinical scores and biomarkers have previously been examined for their ability to predict bacteremia. Conclusive clinical validation of these scores and biomarkers is essential. Read More

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http://dx.doi.org/10.1097/MD.0000000000002264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008518PMC
December 2015
24 Reads

[Work and epilepsy--facts and phantasies].

Authors:
Thomas Dorn

Praxis (Bern 1994) 2015 Nov;104(23):1279-85

1 Klinik Lengg AG, Schweizerische Epilepsieklinik, Zürich.

Epilepsies can affect ability to work in a certain workplace and reintegration capacity not only due the seizures, but also due to possible accompanying neurological, neuropsychological and psychiatric symptoms. Epileptic seizures can lead to injuries of the patient himself and of other persons. Assessment of this aspect in a certain workplace requires not only a detailed knowledge of the nature of this job, but also of the semiology and frequency of seizures must be considered. Read More

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http://dx.doi.org/10.1024/1661-8157/a002188DOI Listing
November 2015