2,940 results match your criteria Scarlet Fever


Changes in M types of Streptococcus pyogenes in Chinese children with scarlet fever.

Lancet Infect Dis 2020 Jul;20(7):780

Shenzhen Children's Hospital, Shenzhen, China; Laboratory of Microbiology and Immunology, Beijing Children's Hospital affiliated to Capital Medical University, Beijing 100045, China. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(20)30441-2DOI Listing

Paediatrics in Theresienstadt ghetto.

Cent Eur J Public Health 2020 Jun;28(2):155-160

Faculty of Education, Comenius University, Bratislava, Slovak Republic.

The main objective of this study is to describe the most common childhood diseases occurring in the Theresienstadt ghetto during the Second World War as well as applied anti-epidemic measures. A partial objective is to describe medical and nursing care of sick child prisoners. The data was obtained by the method of synthesis of primary and secondary data with the highest importance after adequate external source criticism using selected monographs, memoirs, survivor diaries, Orders of the day by the Council of the Elders and Reports of the Jewish self-government of the Theresienstadt ghetto from 1941 to 1945, the Archives of the Jewish Museum in Prague, the Ghetto Museum, the Museum of the History of Polish Jews in Warsaw, Post Bellum online electronic collection of oral historical interviews, and witness accounts. Read More

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http://dx.doi.org/10.21101/cejph.a5557DOI Listing

Increase of emm1 isolates among group A Streptococcus strains causing scarlet fever in Shanghai, China.

Int J Infect Dis 2020 Jun 17. Epub 2020 Jun 17.

Department of Infectious Diseases, Children's Hospital of Fudan University, Shanghai, PR China. Electronic address:

Objective: Scarlet fever epidemics caused by group AStreptococcus (GAS) have been ongoing in China since 2011. However, limited data are available on the dynamic molecular characterizations of the epidemic strains.

Method: Epidemiological data of scarlet fever in Shanghai were obtained from National Notifiable Infectious Disease Surveillance System. Read More

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http://dx.doi.org/10.1016/j.ijid.2020.06.053DOI Listing

Far Eastern Scarlet-Like Fever is a Special Clinical and Epidemic Manifestation of Infection in Russia.

Pathogens 2020 Jun 2;9(6). Epub 2020 Jun 2.

Somov Research Institute of Epidemiology and Microbiology, Ministry of Science and Higher Education, 690087 Vladivostok, Russia.

Pseudotuberculosis in humans until the 1950s was found in different countries of the world as a rare sporadic disease that occurred in the form of acute appendicitis and mesenteric lymphadenitis. In Russia and Japan, the () infection often causes outbreaks of the disease with serious systemic inflammatory symptoms, and this variant of the disease has been known since 1959 as Far Eastern Scarlet-like Fever (FESLF). Russian researchers have proven that the FESLF pathogen is associated with a concrete clonal line of characterized by a specific plasmid profile (pVM82, pYV 48 MDa), sequence (2ST) and gene allele (1st allele). Read More

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http://dx.doi.org/10.3390/pathogens9060436DOI Listing

Alexandroupolis (Dedeagatch): A city born of infections and the first documented death of the Italian civilian Giuseppe Bigheti.

Infez Med 2020 Jun;28(2):273-277

History of Medicine and Anatomy Department, School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.

The choice of Dedeagatch as the place where the station of the Adrianoupolis-Constantinople railway line was to be built was the reason for the foundation of the Greek city of Alexandroupolis (originally under the Ottoman government). The population grew in its early years mainly due to the settlement by railway and construction workers. Meanwhile, poverty, poor hygiene and environmental conditions led to a series of epidemics and various sporadic cases of infections such as malaria, typhoid fever, scarlet fever and tubercolosis, infections which marked the early history of Alexandroupolis. Read More

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[Epidemiological characteristics of scarlet fever in Hubei Province from 2009 to 2018].

Zhonghua Yu Fang Yi Xue Za Zhi 2020 May;54(5):568-571

Institute of Health Inspection and Testing of Hubei Provincial Center for Disease Control and Prevention, Wuhan 430079, China.

Descriptive epidemiological methods were adopted to analyze the epidemiological characteristics of scarlet fever in Hubei Province from 2009 to 2018. During this study, the epidemiological data was obtained from the Chinese Center for Disease Control and Prevention Information System. The results showed that there were 7 329 cases of scarlet fever reported in Hubei Province from 2009 to 2018 and the annual average incidence was 1. Read More

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http://dx.doi.org/10.3760/cma.j.cn112150-20190509-00378DOI Listing

Two females with coronary artery occlusion caused by presumed Kawasaki disease would have delivered without recognition of ischaemic heart disease.

Cardiol Young 2020 Jun 8;30(6):785-789. Epub 2020 May 8.

Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.

We report two females with coronary artery occlusion caused by presumed Kawasaki disease that delivered children without any special treatment. After a 58-year-old female had ventricular tachycardia, a giant coronary artery aneurysm with calcification at the bifurcation of the left coronary artery and segmental stenosis of the right coronary artery were pointed out by CT angiography. She had an episode of sepsis when 3 years old. Read More

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http://dx.doi.org/10.1017/S1047951120001043DOI Listing

Urbanization and mortality in Britain, c. 1800-50.

Econ Hist Rev 2020 May 21;73(2):455-485. Epub 2020 Feb 21.

Cambridge Group for the History of Population and Social Structure, Department of Geography University of Cambridge.

In the long-running debate over standards of living during the industrial revolution, pessimists have identified deteriorating health conditions in towns as undermining the positive effects of rising real incomes on the 'biological standard of living'. This article reviews long-run historical relationships between urbanization and epidemiological trends in England, and then addresses the specific question: did mortality rise especially in rapidly growing industrial and manufacturing towns in the period . 1830-50? Using comparative data for British, European, and American cities and selected rural populations, this study finds good evidence for widespread increases in mortality in the second quarter of the nineteenth century. Read More

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http://dx.doi.org/10.1111/ehr.12964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186836PMC

Infectious diseases in children and adolescents in China: analysis of national surveillance data from 2008 to 2017.

BMJ 2020 04 2;369:m1043. Epub 2020 Apr 2.

Murdoch Children's Research Institute, Parkville, Victoria, Australia.

Objectives: To outline which infectious diseases in the pre-covid-19 era persist in children and adolescents in China and to describe recent trends and variations by age, sex, season, and province.

Design: National surveillance studies, 2008-17.

Setting: 31 provinces in mainland China. Read More

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http://dx.doi.org/10.1136/bmj.m1043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114954PMC

Spatial-temporal analysis and visualization of scarlet fever in mainland China from 2004 to 2017.

Geospat Health 2020 04 2;15(1). Epub 2020 Apr 2.

Key Laboratory of Molecular Epidemiology of Hunan Province, School of Medicine, Hunan Normal University, Changsha, Hunan.

This study retrospectively analyzed the spatio-temporal distribution and spatial clustering of scarlet fever in mainland China from 2004 to 2017. In recent years, the incidence of scarlet fever is increasing. Previous studies on the spatial distribution of scarlet fever in China are mainly focused at the provincial and municipal levels, and there is few systematic report on the spatial and temporal distribution characteristics of scarlet fever on the national level. Read More

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http://dx.doi.org/10.4081/gh.2020.831DOI Listing

Notifiable Respiratory Infectious Diseases in China: A Spatial-Temporal Epidemiology Analysis.

Int J Environ Res Public Health 2020 03 29;17(7). Epub 2020 Mar 29.

School of Public Policy and Administration, Xi'an Jiaotong University, 28 Xianning West Road, Xi'an 710049, China.

Nowadays, tuberculosis, scarlet fever, measles, influenza, and mumps are five major notifiable respiratory infectious diseases (RIDs) in China. The objective of this study was to describe, visualize, and compare the spatial-temporal distributions of these five RIDs from 2006 to 2016. In addition to descriptive epidemiology analysis, seasonality and spatial autocorrelation analysis were also applied to explore the epidemiologic trends and spatial changing patterns of the five RIDs, respectively. Read More

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http://dx.doi.org/10.3390/ijerph17072301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177391PMC

The rash with mucosal ulceration.

Clin Dermatol 2020 Jan - Feb;38(1):35-41. Epub 2019 Oct 25.

Sector of Dermatology and Post-Graduation Course in Dermatology, University Hospital and School of Medicine, Federal University of Rio de Janeiro, Brazil. Electronic address:

A rash is a disseminated eruption of cutaneous lesions with great variation in appearance, cause, and severity. When the physician is facing a rash, the history and physical examination of the patient are extremely important for the identification of the disease and its causal agent. There are various causes for a rash, which may be infectious, allergic, or rheumatologic, besides many others. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2019.10.019DOI Listing
October 2019

[Dramatic achievements in infectious disease prevention and treatment in China during the past 70 years].

Authors:
W Z Yang

Zhonghua Liu Xing Bing Xue Za Zhi 2019 Dec;40(12):1493-1498

Chinese Center for Disease Control and Prevention, Beijing 102206, China.

At the beginning of the founding of People's Republic of China, infectious diseases, such as smallpox, plague, cholera, dysentery, typhoid, measles, diphtheria, pertussis, meningitis, mumps, schistosomiasis, Kala Azar, hemorrhagic fever, leptospirosis, encephalitis B, typhus, malaria, Kala Azar, leprosy, scarlet fever and pinkeye, remained as epidemic in the country and endangered people's health. During the past 70 years, the Chinese government spent huge efforts in infectious disease prevention and treatment by promulgating and implementing series of relative policies, laws and strategies, and also encouraged all Chinese people to participate in. The achievements of these efforts in controlling infectious disease epidemic were extremely successful. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0254-6450.2019.12.001DOI Listing
December 2019

Bacterial, viral, and fungal infection-related risk of Parkinson's disease: Meta-analysis of cohort and case-control studies.

Brain Behav 2020 Mar 4;10(3):e01549. Epub 2020 Feb 4.

Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Aims: Recent studies showed that patients with various bacterial, viral, and fungal infections might be at increased risk of Parkinson's disease (PD). However, the risk of PD in patients with each specific infection varied. This meta-analysis estimated the association between various infections and PD risk. Read More

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http://dx.doi.org/10.1002/brb3.1549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066372PMC

The association between ambient particulate matters, nitrogen dioxide, and childhood scarlet fever in Hangzhou, Eastern China, 2014-2018.

Chemosphere 2020 May 3;246:125826. Epub 2020 Jan 3.

Zhejiang Provincial Centre for Disease Control and Prevention, 3399 Binsheng Road, Binjiang District, Hangzhou, Zhejiang, 310051, China. Electronic address:

Background: The emerging cases of childhood scarlet fever (SF) and worsening air pollution problems in Chinese cities suggests a potential linkage between them. However, few studies had explored this association in a large childhood population.

Methods: We conducted a time-series analysis using the daily count of SF and the daily concentrations of particulate matters with an aerodynamic diameter of 2. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2020.125826DOI Listing

8-year M type surveillance of Streptococcus pyogenes in China.

Lancet Infect Dis 2020 01;20(1):24-25

State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(19)30694-2DOI Listing
January 2020

Epidemiological study of scarlet fever in Shenyang, China.

BMC Infect Dis 2019 Dec 21;19(1):1074. Epub 2019 Dec 21.

Department of Infectious Disease, Shenyang Health Service and Administrative Law Enforcement Center (Shenyang Center for Disease Control and Prevention), Shenyang, 110031, China.

Background: Since 2011, there has been an increase in the incidence of scarlet fever across China. The main objective of this study was to depict the spatiotemporal epidemiological characteristics of the incidence of scarlet fever in Shenyang, China, in 2018 so as to provide the scientific basis for effective strategies of scarlet control and prevention.

Methods: Excel 2010 was used to demonstrate the temporal distribution at the month level and ArcGIS10. Read More

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http://dx.doi.org/10.1186/s12879-019-4705-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925867PMC
December 2019

Against the trend: a decrease in scarlet fever in New Zealand.

Lancet Infect Dis 2019 12;19(12):1285-1286

Department of Paediatrics, Starship Children's Hospital, The University of Auckland, Auckland 1010, New Zealand. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(19)30617-6DOI Listing
December 2019

Identification of Streptococcus pyogenes M1 clone in Canada.

Lancet Infect Dis 2019 12;19(12):1284-1285

Public Health Agency of Canada, National Microbiology Laboratory, Winnipeg, MB R3E 3R2, Canada.

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http://dx.doi.org/10.1016/S1473-3099(19)30622-XDOI Listing
December 2019

Long-term, single-center surveillance of non-invasive group A streptococcal (GAS) infections, emm types and emm clusters.

Eur J Clin Microbiol Infect Dis 2020 Feb 22;39(2):273-280. Epub 2019 Nov 22.

Department of Pediatrics, Carl Gustav Carus University Hospital, Technical University Dresden, Dresden, Germany.

Group A streptococci (GAS) are among the most frequent pathogens in children. Many epidemiological studies focus on specific GAS infections (such as tonsillopharyngitis or invasive disease), on GAS carriers or on post-streptococcal sequelae. By comparison, reports on regional GAS characteristics, particularly circulating non-invasive GAS in Europe, are rare. Read More

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http://dx.doi.org/10.1007/s10096-019-03719-4DOI Listing
February 2020

Genome analysis of a multidrug-resistant Streptococcus sanguis isolated from a throat swab of a child with scarlet fever.

J Glob Antimicrob Resist 2020 Mar 4;20:1-3. Epub 2019 Nov 4.

Hangzhou Center for Disease Control and Prevention, No. 568 Mingshi Road, Hangzhou, Zhejiang, China. Electronic address:

Objectives: A multidrug-resistant strain of the opportunistic pathogen Streptococcus sanguis (S28) was isolated from a throat swab of a child with scarlet fever as a rare case. Genome sequencing and analysis of strain S28 were performed to gain a better understanding of the multidrug resistance mechanisms of S. sanguis and its relationship with scarlet fever. Read More

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http://dx.doi.org/10.1016/j.jgar.2019.10.029DOI Listing

Scarlet fever-the value of microbiological global surveillance.

Authors:

Arch Dis Child 2019 Dec 31;104(12):1173. Epub 2019 Oct 31.

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http://dx.doi.org/10.1136/archdischild-2019-318450DOI Listing
December 2019

Analysis of social and medical portrait of children with pertussis, meningococcal infectious, scarlet fever and estimation of their assigned pharmacotherapy.

Wiad Lek 2019 ;72(9 cz 2):1802-1808

Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine.

Objective: Introduction: The level of childhood bacterial diseases incidence does not have a downward trend. The aim: Conduction of a sociological analysis of medical cards for children with pertussis, meningococcal infection (MI), scarlet fever, and evaluation of consumed pharmacotherapy according to real clinical practice in Ukraine.

Patients And Methods: Materials and methods: 1215 medical cards of inpatients; methods: sociological - document analysis, retrospective frequency. Read More

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November 2019
8 Reads

Analysis of Epidemiological Characteristics of Scarlet Fever in Zhejiang Province, China, 2004-2018.

Int J Environ Res Public Health 2019 09 17;16(18). Epub 2019 Sep 17.

Department of Public Health Surveillance & Advisory, Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Binjiang District, Hangzhou 310051, China.

Objective: The aim of this study was to analyze the trends and epidemiological characteristics of scarlet fever in Zhejiang Province in 2004-2018, intending to provide a basis for targeted prevention and control of this disease.

Method: We collated the epidemiological data for cases of scarlet fever from the China Information System for Disease Control and Prevention (CISDCP) in Zhejiang province between 1 January 2004 and 31 December 2018. Descriptive statistical analysis was used to analyze epidemiological characteristics of scarlet fever, whereas the Getis-Ord Gi* statistic was used to determine the hotspot incidence of scarlet fever. Read More

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http://dx.doi.org/10.3390/ijerph16183454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765783PMC
September 2019
2 Reads

Scarlet fever changes its spots.

Lancet Infect Dis 2019 11 10;19(11):1154-1155. Epub 2019 Sep 10.

School of Chemistry and Molecular Biosciences and Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(19)30494-3DOI Listing
November 2019
2 Reads

Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study.

Lancet Infect Dis 2019 11 10;19(11):1209-1218. Epub 2019 Sep 10.

Department of Infectious Diseases and Medical Research Council Centre for Molecular Bacteriology & Infection, Imperial College London, London, UK; Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, National Institute for Health Research, Imperial College London, London, UK. Electronic address:

Background: Since 2014, England has seen increased scarlet fever activity unprecedented in modern times. In 2016, England's scarlet fever seasonal rise coincided with an unexpected elevation in invasive Streptococcus pyogenes infections. We describe the molecular epidemiological investigation of these events. Read More

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http://dx.doi.org/10.1016/S1473-3099(19)30446-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838661PMC
November 2019
5 Reads

Acute rheumatic fever diagnosis and management: Review of the global implications of the new revised diagnostic criteria with a focus on Saudi Arabia.

J Saudi Heart Assoc 2019 Oct 13;31(4):273-281. Epub 2019 Aug 13.

Department of Cardiology, Prince Sultan Cardiac Center, Riyadh, Saudi ArabiaSaudi Arabia.

Rheumatic fever (RF) is a common cause of acquired heart disease in children worldwide. It is a delayed, nonsuppurative, autoimmune phenomenon following pharyngitis, impetigo, or scarlet fever caused by group A β-hemolytic streptococcal (GAS) infection. RF diagnosis is clinical and based on revised Jones criteria. Read More

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http://dx.doi.org/10.1016/j.jsha.2019.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734099PMC
October 2019
4 Reads

Complementing conventional infectious disease surveillance with national health insurance claims data in the Republic of Korea.

Sci Rep 2019 06 19;9(1):8750. Epub 2019 Jun 19.

Department of Preventive Medicine, Korea University College of Medicine, Seoul, Republic of Korea.

Surveillance remains an important tool for timely outbreak detection and response. Many countries, including Korea, have established national infectious disease surveillance systems with clinical notification. We aimed to evaluate the National Health Insurance Claims-based Surveillance (NHICS) compared to conventional passive report-based National Infectious Diseases Surveillance (NIDS). Read More

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http://dx.doi.org/10.1038/s41598-019-45409-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584579PMC
June 2019
8 Reads

Immune-Related Comorbidities in Childhood-Onset Obsessive Compulsive Disorder: Lifetime Prevalence in the Obsessive Compulsive Disorder Collaborative Genetics Association Study.

J Child Adolesc Psychopharmacol 2019 10 6;29(8):615-624. Epub 2019 Jun 6.

Department of Psychiatry, Faculty of Medicine, British Columbia Children's Hospital, University of British Columbia, Vancouver, Canada.

To evaluate the lifetime prevalence of infectious, inflammatory, and autoimmune disorders in a multisite study of probands with childhood-onset obsessive compulsive disorder (OCD) and their first-degree relatives. Medical questionnaires were completed by 1401 probands and 1045 first-degree relatives in the OCD Collaborative Genetics Association Study. Lifetime prevalence of immune-related diseases was compared with the highest available population estimate and reported as a point estimate with 95% adjusted Wald interval. Read More

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https://www.liebertpub.com/doi/10.1089/cap.2018.0140
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http://dx.doi.org/10.1089/cap.2018.0140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786333PMC
October 2019
15 Reads

Incidence of Scarlet Fever in Children in Jeju Province, Korea, 2002-2016: An Age-period-cohort Analysis.

J Prev Med Public Health 2019 May 24;52(3):188-194. Epub 2019 Apr 24.

Jeju Center for Infection Control, Jeju, Korea.

Objectives: Outbreaks of scarlet fever in Mexico in 1999, Hong Kong and mainland China in 2011, and England in 2014-2016 have received global attention, and the number of notified cases in Korean children, including in Jeju Province, has also increased since 2010. To identify relevant hypotheses regarding this emerging outbreak, an age-period-cohort (APC) analysis of scarlet fever incidence was conducted among children in Jeju Province, Korea.

Methods: This study analyzed data from the nationwide insurance claims database administered by the Korean National Health Insurance Service. Read More

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http://dx.doi.org/10.3961/jpmph.18.299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549015PMC
May 2019
5 Reads

[Study on infectious diseases in Guizhou during the Republic of China].

Authors:
X C Gao A H Hu

Zhonghua Yi Shi Za Zhi 2019 Mar;49(2):83-88

Marxism Institute of Guizhou Normal University, Guiyang 550025, China.

There are many infectious diseases in Guizhou Province during the Republican period, including cholera, smallpox, typhoid, typhus, dysentery, scarlet fever, diphtheria, epidemic cerebrospinal meningitis, recurrent fever, malaria, trachoma, acute conjunctivitis, skin diseases, venereal diseases, leprosy and so on. Natural and social factors together led to the prevalence of infectious diseases during that period. For example, natural factors mainly include Guizhou province's special geographical condition and its frequent flood disasters, and social factors such as the unhealthy lifestyle and low medical level have also caused bad effects. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0255-7053.2019.02.004DOI Listing
March 2019
21 Reads

Staphylococcal scarlet fever associated with staphylococcal enterotoxin M in an elderly patient.

Int J Infect Dis 2019 Aug 13;85:7-9. Epub 2019 May 13.

Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

Staphylococcal scarlet fever (SSF) is characterized by an exanthem without enanthem, bullae, or exfoliation, and is known to be related to Staphylococcus aureus toxins, especially superantigens. It has been reported in children and young adults. Herein, we report the first case of an elderly patient with SSF caused by staphylococcal enterotoxin M (SEM), associated with otitis externa. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S12019712193021
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http://dx.doi.org/10.1016/j.ijid.2019.05.012DOI Listing
August 2019
10 Reads

Detecting spatio-temporal hotspots of scarlet fever in Taiwan with spatio-temporal Gi* statistic.

PLoS One 2019 16;14(4):e0215434. Epub 2019 Apr 16.

Research Center for Humanities and Social Sciences, Academia Sinica, Taipei, Taiwan.

A resurgence of scarlet fever has caused many pediatric infections in East Asia and the United Kingdom. Although scarlet fever in Taiwan has not been a notifiable infectious disease since 2007, the comprehensive national health insurance data can still track its trend. Here, we used data from the open data portal of the Taiwan Centers for Disease Control. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215434PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467404PMC
January 2020
27 Reads

The rash with maculopapules and fever in children.

Clin Dermatol 2019 Mar - Apr;37(2):119-128. Epub 2018 Dec 5.

Dermatology Department, University of CT Health Center, Farmington, Connecticut, USA. Electronic address:

Several medical conditions can cause children to present with fever and a maculopapular rash Although some presentations are benign, others may be medical emergencies, which warrant a prompt diagnosis. We review some of the more common causes of fever and maculopapular dermatitirs, rash including infectious processes (roseola; rubeola; rubella; parvovirus B19; hand, foot, and mouth disease; scarlet fever; meningococcemia; Epstein-Barr virus infection), hypersensitivity reactions (exanthematous drug reactions), and vasculitis syndromes (Kawasaki disease). We have included a diagnostic algorithm to facilitate rapid identification of the etiology of the rash and fever. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0738081X183025
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http://dx.doi.org/10.1016/j.clindermatol.2018.12.005DOI Listing
September 2019
27 Reads

A step beyond the hygiene hypothesis-immune-mediated classes determined in a population-based study.

BMC Med 2019 04 9;17(1):75. Epub 2019 Apr 9.

Department of Psychiatry, Center for Research in Psychiatric Epidemiology and Psychopathology, Lausanne University Hospital, Prilly, Switzerland.

Background: Comorbidity patterns of childhood infections, atopic diseases, and adverse childhood experiences (ACE) are related to immune system programming conditions. The aim of this study was to make a step beyond the hygiene hypothesis and to comprehensively classify these patterns with latent class analysis (LCA). A second aim was to characterize the classes by associations with immunological, clinical, and sociodemographic variables. Read More

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http://dx.doi.org/10.1186/s12916-019-1311-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454751PMC
April 2019
16 Reads
7.249 Impact Factor

Streptococcal superantigen-induced expansion of human tonsil T cells leads to altered T follicular helper cell phenotype, B cell death and reduced immunoglobulin release.

Clin Exp Immunol 2019 07 13;197(1):83-94. Epub 2019 Mar 13.

Department of Medicine, Imperial College London, London, UK.

Streptococcal pyrogenic exotoxin (Spe) A expression is epidemiologically linked to streptococcal tonsillo-pharyngitis and outbreaks of scarlet fever, although the mechanisms by which superantigens confer advantage to Streptococcus pyogenes are unclear. S. pyogenes is an exclusively human pathogen. Read More

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http://dx.doi.org/10.1111/cei.13282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591145PMC
July 2019
8 Reads

Duration of antibiotic treatment for common infections in English primary care: cross sectional analysis and comparison with guidelines.

BMJ 2019 02 27;364:l440. Epub 2019 Feb 27.

Modelling and Economics Unit, National Infection Service, Public Health England, London NW9 5EQ, UK.

Objective: To evaluate the duration of prescriptions for antibiotic treatment for common infections in English primary care and to compare this with guideline recommendations.

Design: Cross sectional study.

Setting: General practices contributing to The Health Improvement Network database, 2013-15. Read More

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http://dx.doi.org/10.1136/bmj.l440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391655PMC
February 2019
29 Reads

Identification of two new core chromosome-encoded superantigens in Streptococcus pyogenes; speQ and speR.

J Infect 2019 05 20;78(5):358-363. Epub 2019 Feb 20.

Department of Infectious Diseases, Imperial College London, London W12 0NN, UK; Department of Molecular Biology & Biotechnology, The Florey Institute, University of Sheffield, Sheffield S10 2TN, UK. Electronic address:

Superantigens are ubiquitous within the Streptococcus pyogenes genome, which suggests that superantigen-mediated T-cell activation provides a significant selective advantage. S. pyogenes can carry a variable complement of the 11 known superantigens. Read More

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http://dx.doi.org/10.1016/j.jinf.2019.02.005DOI Listing
May 2019
7 Reads

Intramural oesophageal abscess: an unusual complication of tonsillitis.

BMJ Case Rep 2019 Feb 6;12(2). Epub 2019 Feb 6.

Department of General Surgery, University Hospital Crosshouse, Kilmarnock, Scotland.

Tonsillitis is an extremely common condition, usually it is self-limiting, of viral origin, and managed conservatively in general practice. Rarely patients require inpatient management, usually when bacterial infection is present or when the cause is virulent organisms such as Epstein Barr virus. Complications can be divided into non-suppurative; sepsis, scarlet fever, rheumatic fever, glomerulonephritis and Lemierres disease, and suppurative; quinsy, parapharyngeal abscess and retropharyngeal abscess, respectively. Read More

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http://dx.doi.org/10.1136/bcr-2018-226010DOI Listing
February 2019
20 Reads

Detection of Epidemic Scarlet Fever Group A Streptococcus in Australia.

Clin Infect Dis 2019 09;69(7):1232-1234

Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia.

Sentinel hospital surveillance was instituted in Australia to detect the presence of pandemic group A Streptococcus strains causing scarlet fever. Genomic and phylogenetic analyses indicated the presence of an Australian GAS emm12 scarlet fever isolate related to United Kingdom outbreak strains. National surveillance to monitor this pandemic is recommended. Read More

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http://dx.doi.org/10.1093/cid/ciz099DOI Listing
September 2019
21 Reads

Effect of meteorological factors on scarlet fever incidence in Guangzhou City, Southern China, 2006-2017.

Sci Total Environ 2019 May 25;663:227-235. Epub 2019 Jan 25.

Guangzhou Center For Disease Control and Prevention, Baiyun District Qi De Road, Guangzhou, Guangdong Province 510440, China.

Objective: To explore the relationship between meteorological factors and scarlet fever incidence from 2006 to 2017 in Guangzhou, the largest subtropical city of Southern China, and assist public health prevention and control measures.

Methods: Data for weekly scarlet fever incidence and meteorological variables from 2006 to 2017 in Guangzhou were collected from the National Notifiable Disease Report System (NNDRS) and the Guangzhou Meteorological Bureau (GZMB). Distributed lag nonlinear models (DLNMs) were conducted to estimate the effect of meteorological factors on weekly scarlet fever incidence in Guangzhou. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.01.318DOI Listing
May 2019
4 Reads

Phylogenetic relationship of prophages is affected by CRISPR selection in Group A Streptococcus.

BMC Microbiol 2019 01 28;19(1):24. Epub 2019 Jan 28.

Department of Microbiology, Graduate School of Medicine, Kyoto University, Kyoto, 606-8501, Japan.

Background: Group A Streptococcus (GAS) is a major human pathogen, which is associated with a wide spectrum of invasive diseases, such as pharyngitis, scarlet fever, rheumatic fever, and streptococcal toxic shock syndrome (STSS). It is hypothesized that differences in GAS pathogenicity are related to the acquisition of diverse bacteriophages (phages). Nevertheless, the GAS genome also harbors clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (cas) genes, which play an important role in eliminating foreign DNA, including those of phages. Read More

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http://dx.doi.org/10.1186/s12866-019-1393-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348661PMC
January 2019
11 Reads

Determinants of inter-practice variation in childhood asthma and respiratory infections: cross-sectional study of a national sentinel network.

BMJ Open 2019 01 24;9(1):e024372. Epub 2019 Jan 24.

Department of Clinical and Experimental Medicine, University of Surrey, Guildford, UK.

Objectives: Respiratory infections are associated with acute exacerbations of asthma and accompanying morbidity and mortality. In this study we explore inter-practice variations in respiratory infections in children with asthma and study the effect of practice-level factors on these variations.

Design: Cross-sectional study. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02437
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http://dx.doi.org/10.1136/bmjopen-2018-024372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347957PMC
January 2019
22 Reads

Seasonality and trend prediction of scarlet fever incidence in mainland China from 2004 to 2018 using a hybrid SARIMA-NARX model.

PeerJ 2019 17;7:e6165. Epub 2019 Jan 17.

School of Public Health, North China University of Science and Technology, Tangshan, China.

Background: Scarlet fever is recognized as being a major public health issue owing to its increase in notifications in mainland China, and an advanced response based on forecasting techniques is being adopted to tackle this. Here, we construct a new hybrid method incorporating seasonal autoregressive integrated moving average (SARIMA) with a nonlinear autoregressive with external input(NARX) to analyze its seasonality and trend in order to efficiently prevent and control this re-emerging disease.

Methods: Four statistical models, including a basic SARIMA, basic nonlinear autoregressive (NAR) method, traditional SARIMA-NAR and new SARIMA-NARX hybrid approaches, were developed based on scarlet fever incidence data between January 2004 and July 2018 to evaluate its temporal patterns, and their mimic and predictive capacities were compared to discover the optimal using the mean absolute percentage error, root mean square error, mean error rate, and root mean square percentage error. Read More

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http://dx.doi.org/10.7717/peerj.6165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339779PMC
January 2019
9 Reads

You're the Flight Surgeon.

Authors:

Aerosp Med Hum Perform 2019 Feb;90(2):139-143

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http://dx.doi.org/10.3357/AMHP.5287.2019DOI Listing
February 2019
6 Reads

Increased Risk for Invasive Group A Streptococcus Disease for Household Contacts of Scarlet Fever Cases, England, 2011-2016.

Emerg Infect Dis 2019 03 17;25(3):529-537. Epub 2019 Mar 17.

The incidence of scarlet fever in England and Wales is at its highest in 50 years. We estimated secondary household risk for invasive group A Streptococcus (iGAS) disease within 60 days after onset of scarlet fever. Reports of scarlet fever in England during 2011-2016 were matched by residential address to persons with laboratory-confirmed iGAS infections. Read More

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http://dx.doi.org/10.3201/eid2503.181518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390732PMC
March 2019
13 Reads
6.751 Impact Factor

[Surveillance data on notifiable infectious diseases among students aged 6-22 years in China, 2011-2016].

Zhonghua Liu Xing Bing Xue Za Zhi 2018 Dec;39(12):1589-1595

Division of Infectious Disease Control and Prevention, Key Laboratory of Surveillance and Early Warning on Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing 102206, China.

To analyze the epidemiological characteristics of notifiable infectious diseases among Chinese students from 2011 to 2016 and to provide reference for the effective prevention and control programs on infectious disease among students. Both morbidity and mortality of notifiable infectious diseases among Chinese students aged 6-22 years from 2011 to 2016 were analyzed, with main characteristics of the disease described. During 2011 to 2016, morbidities of Categories A, B and C infectious diseases among the Chinese students aged 6-22 years showed a decreasing trend, from 248. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0254-6450.2018.12.010DOI Listing
December 2018
32 Reads

Scarlet fever associated with hepatitis in pediatrics. A case report.

Rev Chil Pediatr 2018 Aug;89(4):521-524

Division of Pediatric Gastroenterology, Hepatology and Nutrition, Miller School of Medicine, University of Miami, USA.

Introduction: Scarlet fever is a common illness in pediatrics caused by group A beta-hemolytic strep tococcus (GABHS), which usually occurs after an episode of pharyngitis, and has an overall excellent prognosis. Hepatitis secondary to scarlet fever is a rare complication described in adults and even less frequently in children. Our objective was to describe a case of hepatitis secondary to scarlet fever in a pediatric patient. Read More

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http://dx.doi.org/10.4067/S0370-41062018005000606DOI Listing
August 2018
55 Reads