4,588 results match your criteria Scandinavian Journal of Rheumatology[Journal]


Comparison of agreement between internet-based registration of patient-reported outcomes and clinic-based paper forms within the Swedish Rheumatology Quality Register.

Scand J Rheumatol 2019 Feb 13:1-5. Epub 2019 Feb 13.

a Department of Public Health and Clinical Medicine/Rheumatology , Umeå University , Umeå , Sweden.

Objective: The Swedish Rheumatology Quality Register has implemented an internet-based method (PER) for registering patient-recorded outcome measures. The aim of this study was to compare the agreement between visual analogue scales (VASs) reported via PER and clinic-based reporting using paper forms.

Methods: In a cross-sectional study (70 patients), the results of 79 registrations of VASs for global health, pain, and fatigue from PER were compared with corresponding clinic-based paper registrations. Read More

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http://dx.doi.org/10.1080/03009742.2018.1551964DOI Listing
February 2019
1 Read

Should we biopsy temporal arteries to diagnose giant cell arteritis? A single-centre experience in Japan.

Scand J Rheumatol 2019 Feb 13:1-2. Epub 2019 Feb 13.

a Department of Internal Medicine , Tomakomai City Hospital , Tomakomai , Japan.

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http://dx.doi.org/10.1080/03009742.2018.1563212DOI Listing
February 2019

Increased expression of CD40/TRAF1 and activation of nuclear factor-κκB-dependent proinflammatory gene expression in collagen-induced arthritis.

Scand J Rheumatol 2018 Nov;47(6):455-460

a Department of Rheumatology , The First Affiliated Hospital of Soochow University , Su Zhou , China.

Objective: Genetic studies have implicated both CD40 and tumour necrosis factor receptor-associated factor-1 (TRAF1) with rheumatoid arthritis (RA). CD40 signalling is known to be associated with TRAF1 expression, directly or indirectly; however, the detailed mechanisms of these interactions are not clear in RA, and in particular in fibroblast-like synoviocytes. This study aims to investigate this pathway and the role of nuclear factor-κB (NF-κB) in a mouse model of RA. Read More

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http://dx.doi.org/10.1080/03009742.2018.1432684DOI Listing
November 2018

Fatigue correlates with signs of immunological activity and patient-reported outcomes in patients with primary Sjögren's syndrome.

Scand J Rheumatol 2019 Jan 31:1-2. Epub 2019 Jan 31.

a Department of Internal Medicine , Centre for Rheumatic Diseases, Tampere University Hospital , Tampere , Finland.

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http://dx.doi.org/10.1080/03009742.2018.1559881DOI Listing
January 2019
1 Read

Four distinct clinical phenotypes of vasculitis affecting medium-sized arteries.

Scand J Rheumatol 2019 Jan 23:1-7. Epub 2019 Jan 23.

a Department of Hematology and Rheumatology , Tohoku University Graduate School of Medicine , Sendai , Japan.

Objective: Within the spectrum of polyarteritis nodosa (PAN), cutaneous PAN (cPAN) is further classified into mild cPAN and severe cPAN which presents with ulcers, necrosis, or neuritis. As distinguishing between severe cPAN and systemic PAN can be difficult, this study evaluated the clinical characteristics of patients with necrotizing arteritis of medium-sized arteries.

Methods: Forty-one patients diagnosed with necrotizing arteritis of medium-sized arteries between 2008 and 2017 at our institution were enrolled in this study. Read More

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http://dx.doi.org/10.1080/03009742.2018.1551965DOI Listing
January 2019
1 Read

Rapidly progressive endomyocardial fibrosis and heart failure in a 17-year-old female with limited cutaneous systemic sclerosis.

Scand J Rheumatol 2019 Jan 22:1-2. Epub 2019 Jan 22.

a Copenhagen Lupus and Vasculitis Clinic, Center for Rheumatology and Spine Diseases , Copenhagen University Hospital, Rigshospitalet , Copenhagen , Denmark.

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http://dx.doi.org/10.1080/03009742.2018.1550211DOI Listing
January 2019
1 Read

Cytokines and soluble receptors of the interleukin-1 family in Schnitzler syndrome.

Scand J Rheumatol 2019 Jan 22:1-4. Epub 2019 Jan 22.

b Institute of Protein Biochemistry , National Research Council , Naples , Italy.

Objectives: Schnitzler syndrome (SchS) is an autoinflammatory disorder characterized by chronic urticaria, fever, and monoclonal gammopathy. The success of interleukin-1 (IL-1) blocking therapies suggests a crucial role for IL-1 in disease induction. The aim of this study is to perform a comprehensive analysis of IL-1 family cytokines and soluble receptors in a group of SchS patients. Read More

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http://dx.doi.org/10.1080/03009742.2018.1550210DOI Listing
January 2019
1 Read

Haemophagocytic lymphohistiocytosis associated with leishmaniasis reactivation: a potential adverse event to anti-tumour necrosis factor-α therapy.

Scand J Rheumatol 2018 Dec 10:1-2. Epub 2018 Dec 10.

a Department of Haematology , Herlev and Gentofte University Hospital , Herlev , Denmark.

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http://dx.doi.org/10.1080/03009742.2018.1533035DOI Listing
December 2018

Acute fulminant myocarditis in a patient with primary Sjögren's syndrome.

Scand J Rheumatol 2018 Dec 5:1-2. Epub 2018 Dec 5.

b Department of Cardiology , Tomakomai City Hospital , Tomakomai , Japan.

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http://dx.doi.org/10.1080/03009742.2018.1514068DOI Listing
December 2018
6 Reads

Peripheral blood lymphocyte subset repertoires are biased and reflect clinical features in patients with dermatomyositis.

Scand J Rheumatol 2018 Dec 5:1-5. Epub 2018 Dec 5.

a Department of Rheumatology, Graduate School of Medical and Dental Sciences , Tokyo Medical and Dental University (TMDU) , Tokyo , Japan.

Objective: Dermatomyositis (DM) is an idiopathic inflammatory myopathy which often involves the lungs. DM is likely to be associated with aberrant T- and B-cell activation in the pathogenesis because of the proven effectiveness of T- and B-cell-targeted treatments. Assuming that the aberrant activation is reflected by biases in the lymphocyte subset repertoires, we aimed to elucidate these biases, especially in relation to clinical features of DM. Read More

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http://dx.doi.org/10.1080/03009742.2018.1530371DOI Listing
December 2018
1 Read

Phenotypic features and predictors of the clinical severity of keratoconjunctivitis sicca and salivary gland dysfunction in patients with Sjögren's syndrome: a longitudinal analysis of the Korean Initiative of primary Sjögren's Syndrome (KISS) cohort.

Scand J Rheumatol 2018 Nov 26:1-9. Epub 2018 Nov 26.

b Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine , The Catholic University of Korea , Seoul , Republic of Korea.

Objective: The aim was to investigate prevalence and degree of ocular and oral involvement in patients with primary Sjögren's syndrome (PSS).

Method: We analysed 134 participants from the Korean Initiative of PSS cohort who completed a 2 year follow-up oral and ocular sign test. The severity of keratoconjunctivitis sicca (KCS) was determined with the Schirmer I test value (STV) [abnormal (AB) ≤ 5 mm/5 min; normal (N) > 5 mm/5 min]. Read More

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http://dx.doi.org/10.1080/03009742.2018.1504982DOI Listing
November 2018
5 Reads

Increased expression of the proprotein convertase enzyme FURIN in rheumatoid arthritis.

Scand J Rheumatol 2018 Nov 26:1-5. Epub 2018 Nov 26.

a Faculty of Medicine and Life Sciences , University of Tampere , Tampere , Finland.

Objective: FURIN is a proprotein convertase enzyme that inhibits the proinflammatory function of T cells and myeloid cells. Elevated FURIN expression levels have been reported in immune-mediated diseases, such as primary Sjögren's syndrome. Here, we investigated the levels of FURIN in peripheral blood (PB) and synovial fluid (SF) leucocytes from patients with rheumatoid arthritis (RA). Read More

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http://dx.doi.org/10.1080/03009742.2018.1520294DOI Listing
November 2018
7 Reads

Cardiovascular risk factors and incident giant cell arteritis: a population-based cohort study.

Scand J Rheumatol 2018 Nov 21:1-5. Epub 2018 Nov 21.

h Division of Rheumatology , University of Pennsylvania , Philadelphia , PA , USA.

Objective: To assess the strength of the effect of cardiovascular risk factors on the incidence of giant cell arteritis (GCA) in a general population context.

Method: Data from the Reykjavik Study (RS), a population-based cohort study focusing on cardiovascular disease, were used. Everyone born in 1907-1935 living in Reykjavik, Iceland, or adjacent communities on 1 December 1967 were invited to participate. Read More

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http://dx.doi.org/10.1080/03009742.2018.1506821DOI Listing
November 2018
10 Reads

Comparing patient-reported outcomes entered at home versus at hospital, and testing touch screens for initial recruitment to scientific trials in arthritis patients.

Scand J Rheumatol 2018 Nov 16:1-7. Epub 2018 Nov 16.

a The Danish Rheumatologic Database (DANBIO) and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet , Glostrup , Denmark.

Objectives: Touch screens for entering patient-reported outcomes (PROs) are available at all Danish departments of rheumatology reporting to the nationwide DANBIO registry. This project comprises two substudies in patients with rheumatoid arthritis (RA) or axial spondyloarthritis (AxSpA), aiming to (A) investigate the feasibility of first line patient recruitment for research via touch screens, and (B) compare PROs collected at hospital versus at home, including patient preferences.

Method: Substudy A: using a touch screen, patients answered whether we could contact them about a clinical research project (yes/no). Read More

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http://dx.doi.org/10.1080/03009742.2018.1522666DOI Listing
November 2018
12 Reads

Dose reduction of biological therapies for inflammatory rheumatic diseases: what do patients think?

Scand J Rheumatol 2018 Nov 16:1-2. Epub 2018 Nov 16.

a Rheumatology Department , University Hospital Southampton NHS Foundation Trust , Southampton , UK.

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http://dx.doi.org/10.1080/03009742.2018.1533034DOI Listing
November 2018
13 Reads

Structural progression rate decreases over time on serial radiography and magnetic resonance imaging of sacroiliac joints and spine in a five-year follow-up study of patients with ankylosing spondylitis treated with tumour necrosis factor inhibitor.

Scand J Rheumatol 2018 Nov 13:1-13. Epub 2018 Nov 13.

a Center for Rheumatology and Spine Diseases , Rigshospitalet , Copenhagen , Denmark.

Objective: To investigate temporal changes in structural progression assessed by serial conventional radiography and magnetic resonance imaging (MRI) of the sacroiliac joints (SIJs) and spine in patients with ankylosing spondylitis (AS) treated with tumour necrosis factor (TNF) inhibitor for 5 years.

Method: Forty-two patients were included and 33 patients were followed for 5 years in a prospective investigator-initiated study. Conventional radiographs were required four times and MRI seven times. Read More

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https://www.tandfonline.com/doi/full/10.1080/03009742.2018.1
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http://dx.doi.org/10.1080/03009742.2018.1506822DOI Listing
November 2018
12 Reads

'Isn't biological treatment something healthy?' Lay people's perceptions of medical terms.

Scand J Rheumatol 2018 Nov 13:1-3. Epub 2018 Nov 13.

a Department of Rheumatology , King Christian X Hospital for Rheumatic Diseases , Graasten , Denmark.

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http://dx.doi.org/10.1080/03009742.2018.1522667DOI Listing
November 2018
2 Reads

Diagnostic performance of a new anti-carbamylated protein assay in rheumatic diseases.

Scand J Rheumatol 2018 Nov 13:1-2. Epub 2018 Nov 13.

a Exagen Diagnostics , Vista , CA , USA.

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http://dx.doi.org/10.1080/03009742.2018.1530372DOI Listing
November 2018

Comparison of patients with and without pre-existing lymphoma at diagnosis of primary Sjögren's syndrome.

Scand J Rheumatol 2018 Nov 13:1-6. Epub 2018 Nov 13.

a Department of Medical Sciences, Section of Rheumatology , Uppsala University , Uppsala , Sweden.

Objective: In the 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren's syndrome (pSS), pre-existing lymphoma is not an exclusion criterion for pSS diagnosis, as in earlier criteria. We aimed to explore whether there are differences between pSS patients with and without pre-existing lymphoma at pSS diagnosis.

Method: Patients with ICD-7-10 codes for Sjögren's syndrome (SS) and a diagnosis of malignant lymphoma before or after SS diagnosis were identified by linking the Swedish Patient Register 1964-2007 with the Cancer Register 1990-2007 (n = 224). Read More

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http://dx.doi.org/10.1080/03009742.2018.1523456DOI Listing
November 2018
6 Reads

Adalimumab versus adalimumab and methotrexate for the treatment of juvenile idiopathic arthritis: long-term data from the German BIKER registry.

Scand J Rheumatol 2018 Nov 9:1-10. Epub 2018 Nov 9.

a Department of Paediatrics , Centre for Paediatric Rheumatology, Asklepios Clinic Sankt Augustin , Sankt Augustin , Germany.

Objective: Adalimumab (ADA) has become a valuable treatment option for juvenile idiopathic arthritis (JIA). The importance of combination with methotrexate (MTX) is unclear.

Method: Data from the German Biologics in Paediatric Rheumatology (BIKER) registry are reported. Read More

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https://www.tandfonline.com/doi/full/10.1080/03009742.2018.1
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http://dx.doi.org/10.1080/03009742.2018.1488182DOI Listing
November 2018
9 Reads

No preventive or therapeutic efficacy of infliximab against macrophage activation syndrome due to systemic juvenile idiopathic arthritis.

Scand J Rheumatol 2018 Nov 8:1-3. Epub 2018 Nov 8.

a Department of Nephrology and Rheumatology , National Center for Child Health and Development , Tokyo , Japan.

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http://dx.doi.org/10.1080/03009742.2018.1493745DOI Listing
November 2018

Hypertrophic pachymeningitis associated with antineutrophil cytoplasmic antibody-associated vasculitis: a case series of 15 patients.

Scand J Rheumatol 2018 Nov 5:1-7. Epub 2018 Nov 5.

a Department of Nephrology and Rheumatology , Gunma University Graduate School of Medicine , Gunma , Japan.

Objective: We aimed to describe the clinical characteristics and treatment course of hypertrophic pachymeningitis (HPM) in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).

Methods: We retrospectively analysed 15 patients (11 men and four women). HPM was diagnosed based on thickening and enhancing of the brain and/or spinal dura mater on gadolinium-enhanced magnetic resonance imaging (MRI) T1 sequence. Read More

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http://dx.doi.org/10.1080/03009742.2018.1498916DOI Listing
November 2018
1 Read

Changes in disability and their relationship with skin thickening, in diffuse and limited cutaneous systemic sclerosis: a retrospective cohort study.

Scand J Rheumatol 2018 Nov 5:1-5. Epub 2018 Nov 5.

a Centre for Musculoskeletal Research , The University of Manchester, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre , Manchester , UK.

Objective: The burden of disability associated with systemic sclerosis (SSc) is being increasingly recognized. Our aim was to test the hypothesis that changes in functional ability over time differ between patients with limited (lcSSc) and diffuse cutaneous (dcSSc) subtypes, and that in dcSSc (but not lcSSc) these changes correlate with skin thickening.

Method: This was a retrospective analysis of data collected prospectively between 2005 and 2016 at a single centre. Read More

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http://dx.doi.org/10.1080/03009742.2018.1523455DOI Listing
November 2018
9 Reads

Long-term outcomes and predictors of a large cohort of idiopathic retroperitoneal fibrosis patients: a retrospective study.

Authors:
J Zhao J Li Z Zhang

Scand J Rheumatol 2018 Sep 30:1-7. Epub 2018 Sep 30.

a Department of Rheumatology and Clinical Immunology , Peking University First Hospital , Beijing , China.

Objectives: Idiopathic retroperitoneal fibrosis (iRPF) is an uncommon disease with inflammatory features. Most patients have good prognosis but some may relapse or even progress to chronic renal failure. The aims of the study were to investigate the prognosis of a large cohort of iRPF patients and explore the risk factors for poor outcomes. Read More

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http://dx.doi.org/10.1080/03009742.2018.1497700DOI Listing
September 2018
9 Reads

Disability and health-related quality of life are associated with restricted social participation in young adults with juvenile idiopathic arthritis.

Scand J Rheumatol 2018 Sep 30:1-9. Epub 2018 Sep 30.

d Orton Orthopaedic Hospital , Orton, Helsinki , Finland.

Objectives: To describe a cohort of Finnish juvenile idiopathic arthritis (JIA) patients, to recognize those young adults who are at risk of becoming socially restricted by their long-term rheumatic disease, and to assess which areas of self-rated health-related quality of life (HRQoL) are associated with the emergence of restricted social participation.

Methods: A total of 195 young adults with JIA completed questionnaires addressing demographics, health behaviour, physical activity, functional ability, HRQoL, depressive symptoms, and self-esteem. Patients were classified as having non-restricted social participation if they were engaged in studying, working, maternity leave, or military service, and restricted social participation if they were unemployed or on disability pension. Read More

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http://dx.doi.org/10.1080/03009742.2018.1493140DOI Listing
September 2018
23 Reads

Increased B-cell activating factor, interleukin-6, and interleukin-8 in induced sputum from primary Sjögren's syndrome patients.

Scand J Rheumatol 2018 Sep 30:1-8. Epub 2018 Sep 30.

a Department of Clinical Sciences Malmö, Section of Rheumatology , Lund University , Malmö , Sweden.

Objective: Small airway disease and chronic obstructive pulmonary disease are common in primary Sjögren's syndrome (pSS). However, the underlying inflammatory mechanisms behind pSS-associated airway disease have not been studied in detail. We therefore wanted to study cytokine and leucocyte levels in induced sputum in never-smoking patients with pSS. Read More

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http://dx.doi.org/10.1080/03009742.2018.1473488DOI Listing
September 2018
2 Reads

Anti-citrullinated protein antibodies and arthritis in Sjögren's syndrome: a systematic review and meta-analysis.

Scand J Rheumatol 2018 Sep 30:1-7. Epub 2018 Sep 30.

b Department of Immunology and Rheumatology , National Institute of Medical Science and Nutrition Salvador Zubiran , Mexico City , México.

Objective: The presence of anti-citrullinated protein antibodies (ACPAs) in primary Sjögren's syndrome (pSS) ranges from 3% to 9.9%; however, there is no agreement about their clinical significance. Our aim was to systematically review the literature regarding the association of arthritis and ACPAs in pSS and their role in the development of rheumatoid arthritis (RA). Read More

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http://dx.doi.org/10.1080/03009742.2018.1469164DOI Listing
September 2018
4 Reads

Interleukin-18 is associated with the presence of interstitial lung disease in rheumatoid arthritis: a cross-sectional study.

Scand J Rheumatol 2018 Sep 30:1-8. Epub 2018 Sep 30.

a Department of Rheumatology and Clinical Immunology, Graduate School of Medicine , Kyoto University , Kyoto , Japan.

Objective: Serum interleukin-18 (IL-18) levels are increased in patients with interstitial lung disease (ILD). In addition, IL-18 levels are increased in patients with rheumatoid arthritis (RA) and are associated with arthritis activity. We determined whether increased IL-18 levels are associated with ILD in RA. Read More

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http://dx.doi.org/10.1080/03009742.2018.1477989DOI Listing
September 2018
2 Reads

Peptidylarginine deiminase-4 gene polymorphisms are associated with systemic lupus erythematosus and lupus nephritis.

Scand J Rheumatol 2018 Sep 30:1-8. Epub 2018 Sep 30.

d Copenhagen Lupus and Vasculitis Clinic, Center for Rheumatology and Spine Diseases, Section 4242 , Copenhagen University Hospital Rigshospitalet , Copenhagen , Denmark.

Objective: Peptidylarginine deiminase-4 (PAD4) is highly expressed by neutrophils and essential for citrullination occurring during the formation of neutrophil extracellular traps, which have been implicated in the pathogenesis of systemic lupus erythematosus (SLE) and lupus nephritis (LN). Single-nucleotide polymorphisms (SNPs) in PADI4 influence PAD4 expression and functionality. Here, we investigate whether SNPs in PADI4 influence the risk of SLE or LN. Read More

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https://www.tandfonline.com/doi/full/10.1080/03009742.2018.1
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http://dx.doi.org/10.1080/03009742.2018.1488273DOI Listing
September 2018
3 Reads

Unexpected acute lymphocytic virus-negative myocarditis in a patient with limited cutaneous systemic sclerosis: a case report.

Scand J Rheumatol 2018 Sep 30:1-2. Epub 2018 Sep 30.

a Unit of Immunology, Rheumatology, Allergy and Rare Disease , IRCCS San Raffaele Hospital , Milan , Italy.

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http://dx.doi.org/10.1080/03009742.2018.1493744DOI Listing
September 2018
2 Reads

A case of Kennedy's disease misdiagnosed as polymyositis.

Scand J Rheumatol 2018 Sep 30:1-3. Epub 2018 Sep 30.

a Department of Rheumatology , Guangzhou General Hospital of Guangzhou Military Command , Guangzhou , China.

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http://dx.doi.org/10.1080/03009742.2018.1488989DOI Listing
September 2018
1 Read

Smoking and response to rituximab in rheumatoid arthritis: results from an international European collaboration.

Scand J Rheumatol 2019 Jan 27;48(1):17-23. Epub 2018 Sep 27.

a Rheumatology Unit, Department of Medicine , Karolinska University Hospital and Karolinska Institutet , Stockholm , Sweden.

Objectives: To investigate whether smoking habits predict response to rituximab (RTX) in rheumatoid arthritis (RA).

Method: We included patients from the CERERRA international cohort receiving the first treatment cycle with available smoking status (n = 2481, smokers n = 528, non-current smokers n = 1953) and at least one follow-up visit. Outcome measures were change in Disease Activity Score based on 28-joint count (ΔDAS28) and European League Against Rheumatism (EULAR) good response at 6 months, with non-current smokers as the referent group. Read More

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https://www.tandfonline.com/doi/full/10.1080/03009742.2018.1
Publisher Site
http://dx.doi.org/10.1080/03009742.2018.1466363DOI Listing
January 2019
17 Reads

Eosinophilic granulomatosis with polyangiitis mimicking peripheral T-cell lymphoma, not otherwise specified.

Scand J Rheumatol 2018 Aug 28:1-2. Epub 2018 Aug 28.

a Department of Internal Medicine , Tomakomai City Hospital , Tomakomai , Japan.

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https://www.tandfonline.com/doi/full/10.1080/03009742.2018.1
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http://dx.doi.org/10.1080/03009742.2018.1493746DOI Listing
August 2018
12 Reads

Use of disease-modifying anti-rheumatic or anti-tumour necrosis factor drugs and risk of hospitalized infection in ankylosing spondylitis.

Scand J Rheumatol 2018 Aug 16:1-7. Epub 2018 Aug 16.

a Centre for Outcome Research and Evaluation (CORE) , McGill University , Montreal , Canada.

Objective: To assess the risk of hospitalized infection among initiators of disease-modifying anti-rheumatic drugs (DMARDs) and/or anti-tumour necrosis factor (anti-TNF) agents in ankylosing spondylitis (AS).

Method: We studied AS patients, new users of anti-TNF drugs and/or DMARDs between 1 January 2001 and 31 December 2011. Cohort entry was defined as the date of first prescription of any of these drugs. Read More

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http://dx.doi.org/10.1080/03009742.2018.1470253DOI Listing
August 2018
1 Read

Extremely poor patient-reported outcomes are associated with lack of clinical response and decreased retention rate of tumour necrosis factor inhibitor treatment in patients with axial spondyloarthritis.

Scand J Rheumatol 2018 Aug 13:1-5. Epub 2018 Aug 13.

a The DANBIO Registry and Copenhagen Center for Arthritis Research (COPECARE) , Center for Rheumatology and Spine Diseases, Rigshospitalet , Glostrup , Denmark.

Objective: To investigate whether axial spondyloarthritis (axSpA) patients with extremely poor patient-reported outcomes (PROs) at start of first tumour necrosis factor inhibitor (TNFi) treatment have poorer treatment response and shorter treatment retention than other patients.

Method: This observational cohort study was based on the nationwide DANBIO registry. Patients with axSpA who started first TNFi during 2011-2016 were stratified according to baseline Bath Ankylosing Spondylitis Disease Activity Index (BASDAI ≥ 0. Read More

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http://dx.doi.org/10.1080/03009742.2018.1481225DOI Listing

Anti-cyclic citrullinated peptide antibodies, 28-joint Disease Activity Score, and magnetic resonance imaging bone oedema at baseline predict 11 years' functional and radiographic outcome in early rheumatoid arthritis.

Scand J Rheumatol 2019 Jan 13;48(1):1-8. Epub 2018 Aug 13.

l King Christian X's Hospital for Rheumatic Diseases , University of Southern Denmark , Gråsten , Denmark.

Objective: To investigate the clinical and radiographic status, and to identify baseline predictors of functional status and erosive progression at 11 years' follow-up of early rheumatoid arthritis (RA) patients.

Methods: Patients enrolled in the Danish investigator-initiated randomized controlled CIMESTRA trial, which investigated a 2 year treat-to-target intervention with methotrexate and intra-articular glucocorticoids with or without cyclosporine, were followed up. The 28-joint Disease Activity Score (DAS28), Health Assessment Questionnaire (HAQ) score, and total Sharp van der Heijde score (TSS) were assessed at baseline and 11 years. Read More

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http://dx.doi.org/10.1080/03009742.2018.1466362DOI Listing
January 2019
1 Read

Healthcare costs and outcomes in adult patients with juvenile idiopathic arthritis: a population-based study.

Scand J Rheumatol 2018 Aug 2:1-7. Epub 2018 Aug 2.

h Rheumatology Department , Jyväskylä Central Hospital , Jyväskylä , Finland.

Objectives: Evidence of the economic burden and long-term outcomes of juvenile idiopathic arthritis (JIA) remains scarce. Our aim was to explore healthcare costs and long-term outcomes in adult patients with JIA.

Method: We identified all adult patients (≥ 18 years) with JIA who visited Jyväskylä Central Hospital rheumatology unit between May 2007 and March 2016. Read More

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http://dx.doi.org/10.1080/03009742.2018.1475580DOI Listing
August 2018
1 Read

Biological treatment in ankylosing spondylitis in the Nordic countries during 2010-2016: a collaboration between five biological registries.

Scand J Rheumatol 2018 Nov 2;47(6):465-474. Epub 2018 Aug 2.

c Department of Rheumatology and Inflammation Research, Sahlgrenska Academy , University of Gothenburg , Gothenburg , Sweden.

Objectives: Large-scale observational cohorts may be used to study the effectiveness and rare side effects of biological disease-modifying anti-rheumatic drugs (bDMARDs) in ankylosing spondylitis (AS), but may be hampered by differences in baseline characteristics and disease activity across countries. We aimed to explore the research infrastructure in the five Nordic countries regarding bDMARD treatment in AS.

Method: This observational cohort study was based on data from biological registries in Denmark (DANBIO), Sweden (SRQ/ARTIS), Finland (ROB-FIN), Norway (NOR-DMARD), and Iceland (ICEBIO). Read More

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http://dx.doi.org/10.1080/03009742.2018.1444199DOI Listing
November 2018
2 Reads

Muscle endurance, strength, and active range of motion in patients with different subphenotypes in systemic sclerosis: a cross-sectional cohort study.

Scand J Rheumatol 2018 Aug 2:1-8. Epub 2018 Aug 2.

c Functional Area Occupational Therapy and Physiotherapy, Allied Health Professionals Function , Karolinska University Hospital , Stockholm , Sweden.

Objective: Proximal muscle weakness is common in patients with systemic sclerosis (SSc). Dynamic muscle endurance, muscle strength in the lower extremities, and active range of motion (AROM) in the upper extremities are less studied. We investigated functional muscle endurance, strength, and AROM, and explored differences depending on skin and/or lung involvement in SSc patients. Read More

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http://dx.doi.org/10.1080/03009742.2018.1477990DOI Listing
August 2018
2 Reads

Differences associated with age at onset in early systemic sclerosis patients: a report from the EULAR Scleroderma Trials and Research Group (EUSTAR) database.

Scand J Rheumatol 2019 Jan 24;48(1):42-51. Epub 2018 Jul 24.

t Rheumatology A Department , Cochin Hospital, APHP, Paris Descartes University , Paris , France.

Objective: The aim of this study was to analyse differences in clinical presentation in patients with early (< 3 years' duration) systemic sclerosis (SSc), comparing three age groups according to disease subsets.

Method: Cross-sectional analysis of the prospective EULAR Scleroderma Trials and Research database (EUSTAR) was performed. Patients fulfilling preliminary American College of Rheumatology 1980 classification criteria for SSc, with < 3 years from the first non-Raynaud's SSc symptom at first entry, were selected. Read More

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http://dx.doi.org/10.1080/03009742.2018.1459830DOI Listing
January 2019
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Helicobacter pylori infection is not associated with rheumatoid arthritis.

Scand J Rheumatol 2019 Jan 17;48(1):24-31. Epub 2018 Jul 17.

c Department of Hepatology and Gastroenterology , Aarhus University Hospital , Aarhus , Denmark.

Objective: Rheumatoid arthritis (RA) is an autoinflammatory disease caused by genetic susceptibility and environmental triggers, which include infectious agents. Helicobacter pylori, a bacterium that frequently colonizes the stomach, is associated with the development of certain autoinflammatory disorders. This study examined a possible association between H. Read More

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http://dx.doi.org/10.1080/03009742.2018.1464205DOI Listing
January 2019
2 Reads

Associations of circulating cell-free microRNA with vasculopathy and vascular events in systemic lupus erythematosus patients.

Scand J Rheumatol 2019 Jan 9;48(1):32-41. Epub 2018 Jul 9.

b Department of Autoimmunology and Biomarkers , Statens Serum Institut , Copenhagen , Denmark.

Objective: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a high risk of atherosclerosis and cardiovascular disease (CVD). MicroRNAs (miRNAs) are small non-coding RNAs that modulate protein translation, and dysregulation is seen in autoimmunity, atherosclerosis, and CVD. We investigate associations between circulating miRNAs and markers of atherosclerosis in SLE patients. Read More

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http://dx.doi.org/10.1080/03009742.2018.1450892DOI Listing
January 2019
2 Reads

Predictive value of a multi-biomarker disease activity score for clinical remission and radiographic progression in patients with early rheumatoid arthritis: a post-hoc study of the OPERA trial.

Scand J Rheumatol 2019 Jan 9;48(1):9-16. Epub 2018 Jul 9.

a Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet , Glostrup , Denmark.

Objectives: Measurement of serum biomarkers at disease onset may improve prediction of disease course in patients with early rheumatoid arthritis (RA). We evaluated the multi-biomarker disease activity (MBDA) score and early changes in MBDA score for prediction of 28-joint Disease Activity Score based on C-reactive protein (DAS28-CRP) remission and radiographic progression in the double-blinded OPERA trial.

Method: Treatment-naïve RA patients (N = 180) with moderate or high DAS28 were randomized to methotrexate (MTX) + adalimumab (n = 89) or MTX + placebo (n = 91) in combination with glucocorticoid injection into swollen joints. Read More

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http://dx.doi.org/10.1080/03009742.2018.1464206DOI Listing
January 2019
2 Reads

Spontaneous remission in large-vessel vasculitis: Takayasu arteritis and paraneoplastic disorder associated with thymic carcinoma.

Scand J Rheumatol 2019 Jan 5;48(1):79-81. Epub 2018 Jul 5.

a Department of Rheumatology and Clinical Immunology , Kobe University Graduate School of Medicine , Kobe , Japan.

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http://dx.doi.org/10.1080/03009742.2018.1469165DOI Listing
January 2019

High prevalence of widespread pain in women with early rheumatoid arthritis.

Scand J Rheumatol 2018 11 5;47(6):447-454. Epub 2018 Jul 5.

a Institute of Neuroscience and Physiology, Section of Health and Rehabilitation, Physiotherapy, Sahlgrenska Academy , University of Gothenburg , Gothenburg , Sweden.

Objectives: The aim of the study was to determine the prevalence of widespread pain (WP) in women with early rheumatoid arthritis (RA) and to compare physical function, activity limitations, health-related quality of life, mental distress, and disease activity between women with WP and non-widespread pain (NWP).

Method: This cross-sectional study included 102 women with early RA. Participants were provided with self-reported questionnaires quantifying activity limitations, physical activity, pain intensity, health-related quality of life, and fatigue. Read More

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http://dx.doi.org/10.1080/03009742.2018.1447683DOI Listing
November 2018
4 Reads

First reported bisphosphonate-related spontaneous oral-nasal fistula: a case report.

Scand J Rheumatol 2019 Jan 2;48(1):85-86. Epub 2018 Jul 2.

a Maxillofacial Institute , Teknon Medical Centre Barcelona , Barcelona , Spain.

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http://dx.doi.org/10.1080/03009742.2018.1466364DOI Listing
January 2019
6 Reads

Metabolic risk factors and the incidence and progression of radiographic hand osteoarthritis: a population-based cohort study.

Scand J Rheumatol 2019 Jan 28;48(1):52-63. Epub 2018 Jun 28.

a Arthritis Research UK Primary Care Centre, Research Institute for Primary Care and Health Sciences , Keele University , Staffordshire , UK.

Objective: To determine whether selected metabolic factors are associated with greater amounts of radiographic hand osteoarthritis (OA) incidence and progression.

Methods: The study identified 706 adults, aged 50-69 years, with hand pain and hand radiographs at baseline, from two population-based cohorts. Metabolic factors (body mass index, hypertension, dyslipidaemia, and diabetes) were ascertained at baseline by direct measurement and medical records. Read More

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http://dx.doi.org/10.1080/03009742.2018.1459831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319183PMC
January 2019
3 Reads

Reliability of pressure pain, vibration detection, and tactile detection threshold measurements in lower extremities in subjects with knee osteoarthritis and healthy controls.

Scand J Rheumatol 2018 Nov 25;47(6):491-500. Epub 2018 Jun 25.

e Department of Physical and Rehabilitation Medicine , Helsinki University Hospital , Helsinki , Finland.

Objectives: Quantitative sensory testing (QST) is a method to assess somatosensory function in osteoarthritis (OA), but reliability data on the performance of different QST modalities on different joint structures are missing. The main aims of our study were to assess intertester and intratester reliability of tactile detection thresholds (TDTs), vibration detection thresholds (VDTs), and pressure pain thresholds (PPTs) on different knee joint structures.

Method: In total, 32 subjects with knee OA and 32 volunteers with healthy knees participated. Read More

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http://dx.doi.org/10.1080/03009742.2018.1433233DOI Listing
November 2018
4 Reads