9,575 results match your criteria Scandinavian Journal of Infectious Diseases[Journal]


The importance of surgery in colorectal cancer treatment.

Authors:
Eva Angenete

Lancet Oncol 2018 Dec 10. Epub 2018 Dec 10.

Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital/Östra, Scandinavian Surgical Outcomes Research Group, 413 45 Gothenburg, Sweden. Electronic address:

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December 2018

Decreased mortality, laparotomy, and embolization rates for liver injuries during a 13-year period in a major Scandinavian trauma center.

Trauma Surg Acute Care Open 2018 5;3(1):e000205. Epub 2018 Nov 5.

Department of Traumatology, Oslo University Hospital Ulleval, Oslo, Norway.

Background: Although non-operative management (NOM) has become the treatment of choice in hemodynamically normal patients with liver injuries, the optimal management of Organ Injury Scale (OIS) grades 4 and 5 injuries is still controversial. Oslo University Hospital Ulleval (OUHU) has since 2008 performed angiography only with signs of bleeding. Simultaneously, damage control resuscitation was implemented. Read More

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November 2018
3 Reads

Use of liraglutide and risk of major cardiovascular events: a register-based cohort study in Denmark and Sweden.

Lancet Diabetes Endocrinol 2018 Dec 5. Epub 2018 Dec 5.

Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark. Electronic address:

Background: Trial evidence shows that the glucagon-like peptide-1 receptor agonist liraglutide significantly reduces the risk of major cardiovascular events among patients with type 2 diabetes who have established cardiovascular disease or are at high cardiovascular risk. We aimed to assess the cardiovascular effectiveness of liraglutide in routine clinical practice.

Methods: We used data from nationwide registers in Denmark and Sweden for the period from Jan 1, 2010, to Dec 31, 2016, to investigate the risk of major cardiovascular events associated with use of liraglutide, compared with an active comparator drug class, dipeptidyl peptidase-4 (DPP-4) inhibitors, in patients with type 2 diabetes. Read More

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December 2018
1 Read

"Candidatus Neoehrlichia mikurensis" in Ixodes ricinus ticks collected near the Arctic Circle in Norway.

Parasit Vectors 2018 Dec 4;11(1):620. Epub 2018 Dec 4.

Division of Medical Microbiology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

Background: "Candidatus Neoehrlichia mikurensis" is a gram-negative bacterium belonging to the family Anaplasmataceae that, in Europe, is transmitted by Ixodes ricinus ticks. "Candidatus N. mikurensis" can cause a severe systemic inflammatory syndrome, neoehrlichiosis, mostly in persons with other underlying diseases. Read More

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December 2018
2 Reads

Endorsement of clinical practice guidelines by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine.

Acta Anaesthesiol Scand 2018 Dec 3. Epub 2018 Dec 3.

Department of Intensive Care, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

Clinical practice guidelines from other organizations or societies with assumed clinical and contextualized relevance for Scandinavian Society of Anaesthesiology and Intensive Care Medicine (SSAI) members, may trigger a formal evaluation by The Clinical Practice Committee (CPC) for possible SSAI endorsement. This avoids unnecessary duplicate processes and minimizes resource-waste. Identified guidelines are assessed for endorsement using the Appraisal of Guidelines for REsearch and Evaluation (AGREE) II instrument. Read More

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December 2018
3 Reads

The Inflammatory Response to Ventricular Assist Devices.

Front Immunol 2018 15;9:2651. Epub 2018 Nov 15.

Swansea University Medical School, Swansea, United Kingdom.

The therapeutic use of ventricular assist devices (VADs) for end-stage heart failure (HF) patients who are ineligible for transplant has increased steadily in the last decade. In parallel, improvements in VAD design have reduced device size, cost, and device-related complications. These complications include infection and thrombosis which share underpinning contribution from the inflammatory response and remain common risks from VAD implantation. Read More

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November 2018
1 Read

Latitudinal differences on the global epidemiology of infantile spasms: systematic review and meta-analysis.

Orphanet J Rare Dis 2018 Nov 29;13(1):216. Epub 2018 Nov 29.

Department of Pediatrics, Division of Neurology, University of Toronto, Toronto, Canada.

Background: Infantile spasms represent the catastrophic, age-specific seizure type associated with acute and long-term neurological morbidity. However, due to rarity and heterogenous determination, there is persistent uncertainty of its pathophysiological and epidemiological characteristics. The purpose of the current study was to address a historically suspected latitudinal basis of infantile spasms incidence, and to interrogate a geographical basis of epidemiology, including the roles of latitude and other environmental factors, using meta-analytic and -regression methods. Read More

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November 2018
2 Reads

A new Scandinavian Chamaedrilus species (Clitellata: Enchytraeidae), with additional notes on others.

Zootaxa 2018 Nov 14;4521(3):417-429. Epub 2018 Nov 14.

Systematics and Biodiversity, Department of Biological and Environmental Sciences, University of Gothenburg, Box 463, SE-405 30 Göteborg, Sweden..

Chamaedrilus (earlier referred to as Cognettia) is a well-known genus of terrestrial and limnic enchytraeids, currently with 19 known species in the world. Some of its species are morphologically cryptic and can only be identified using genetic (DNA) information. Many of them reproduce asexually, and the prevalence of sexual mature individuals is generally low in the populations. Read More

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November 2018
4 Reads

Removal of phenol and chlorine from wastewater using steam activated biomass soot and tire carbon black.

J Hazard Mater 2018 Oct 30;365:846-856. Epub 2018 Oct 30.

IKET, Karlsruhe Institute of Technology, 76344 Eggenstein-Leopoldshafen, Germany.

This study aims to demonstrate a novel method for removing toxic chemicals using soot produced from wood and herbaceous biomass pyrolyzed in a drop tube reactor and tire pyrolytic carbon black. The influence of ash content, nanostructure, particle size, and porosity on the filter efficiency of steam activated carbon materials was studied. It has been shown for the first time that steam activated soot and carbon black can remove phenol and chloride with filter efficiencies as high as 95%. Read More

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October 2018
7 Reads

Evaluation of the safety and immunogenicity of the oral inactivated multivalent enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi adults in a double-blind, randomized, placebo-controlled Phase I trial using electrochemiluminescence and ELISA assays for immunogenicity analyses.

Vaccine 2018 Nov 22. Epub 2018 Nov 22.

GUVAX (Gothenburg University Vaccine Research Institute), Dept. of Microbiology and Immunology, Inst. of Biomedicine, University of Gothenburg, Sweden. Electronic address:

The safety and immunogenicity of the second generation oral enterotoxigenic Escherichia coli (ETEC) vaccine ETVAX, consisting of inactivated recombinant E. coli strains over-expressing the colonization factors (CFs) CFA/I, CS3, CS5 and CS6 and the heat labile toxoid LCTBA, were evaluated in Bangladeshi volunteers. To enable analysis of antibody responses against multiple vaccine antigens for subsequent use in small sample volumes from children, a sensitive electrochemiluminescence (ECL) assay for analysis of intestine-derived antibody-secreting cell responses using the antibodies in lymphocyte secretions (ALS) assay was established using Meso Scale Discovery technology. Read More

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November 2018
1 Read
3.624 Impact Factor

Estimating the relative importance of demic and cultural diffusion in the spread of the Neolithic in Scandinavia.

J R Soc Interface 2018 Nov 21;15(148). Epub 2018 Nov 21.

Ancient Cultures of Denmark and the Mediterranean, The National Museum of Denmark, Frederiksholms Kanal 12, 1220 Copenhagen K, Denmark.

Using a database of early farming sites in Scandinavia, we estimate that the spread rate of the Neolithic was in the range 0.44-0.66 km yr This is substantially slower (by about 50%) than the rate in continental Europe. Read More

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November 2018
1 Read

Month-of-birth-effect in multiple sclerosis in Austria.

Mult Scler 2018 Nov 22:1352458518810924. Epub 2018 Nov 22.

Karl Landsteiner Institute for Neuroimmunological and Neurodegenerative Disorders, Sozialmedizinisches Zentrum Ost - Donauspital, Vienna, Austria/Department of Neurology, Sozialmedizinisches Zentrum Ost - Donauspital, Vienna, Austria.

Background:: The month-of-birth-effect (MoBE) describes the finding that multiple sclerosis (MS) patients seem to have been born significantly more frequently in spring, with a rise in May, and significantly less often in autumn and winter with the fewest births in November.

Objectives:: To analyse if the MoBE can also be found in the Austrian MS population, and if so, whether the pattern is similar to the reported pattern in Canada, United Kingdom, and some Scandinavian countries.

Methods:: The data of 7886 MS patients in Austria were compared to all live births in Austria from 1940 to 2010, that is, 7. Read More

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November 2018
6 Reads

Utility and effectiveness of the Scandinavian guidelines to exclude computerized tomography scanning in mild traumatic brain injury - a prospective cohort study.

BMC Emerg Med 2018 Nov 20;18(1):44. Epub 2018 Nov 20.

Clinic of Orthopedic Surgery, Akershus University Hospital, Lørenskog, Norway.

Background: In 2013 the Scandinavian Neurotrauma Committee (SNC) published updated guidelines for the initial management of minimal, mild and moderate traumatic head injuries (MTHI) that included serum analysis of protein S100B as a marker for brain tissue damage. This study reviews the effectiveness of the new guidelines in a clinical setting.

Methods: For all patients admitted to Akershus University Hospital (AHUS) from June 30th 2014 to December 15th 2014 with MTHI a separate form was filled in recording the time, indication and result of any S100B sampling and/or head computer tomography (CT) examinations. Read More

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November 2018
4 Reads

Calls made to the Poisons Information Centre reveal need for improved risk management of cleaning agents in the workplace.

Int J Occup Saf Ergon 2018 Nov 19:1-24. Epub 2018 Nov 19.

a Institute of Environmental Medicine , Karolinska Institutet , Stockholm , Sweden.

Purpose: To investigate chemical injuries caused by cleaning agents and disinfectants by reviewing poison control data.

Methods: We performed a five year retrospective analysis of calls to the Swedish Poisons Information Centre (PIC) concerning occupational use of cleaning agents and disinfectants. In addition, callers for 17 new cases were interviewed. Read More

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November 2018
5 Reads

Evaluation of medical and surgical treatments for hidradenitis suppurativa using real-life data from the Scandinavian registry (HISREG).

J Eur Acad Dermatol Venereol 2018 Nov 19. Epub 2018 Nov 19.

Department of Dermatology, University Hospital of North Norway, Tromsø, Norway.

Background: Hidradenitis suppurativa (HS) substantially affects health-related quality-of-life outcomes. Most treatment options are supported by low quality of evidence without validated outcomes.

Objective: The aim of this study was to evaluate the efficacy of surgical and medical interventions using physician- and patient-reported outcomes registered in HISREG. Read More

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November 2018
4 Reads

Relationships between craniofacial morphology and masticatory muscle activity during isometric contraction at different interocclusal distances.

Arch Oral Biol 2018 Oct 29;98:52-60. Epub 2018 Oct 29.

Section of Orofacial Pain and Jaw Function, Aarhus University, Aarhus, Denmark; Department of Dental Medicine, Karolinska Institutet, Huddinge, Sweden; Scandinavian Centre for Orofacial Neuroscience (SCON). Electronic address:

Objective: The aim was to investigate relationships amongst interocclusal distances, masticatory muscle electromyographic (EMG) activity during isometric contraction of masticatory muscles, and craniofacial morphology.

Design: Twenty-eight women and 12 men (25.3 ± 3. Read More

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October 2018
2 Reads

Prevalence and normative values for jaw functional limitations in the general population in Sweden.

Oral Dis 2018 Nov 17. Epub 2018 Nov 17.

Department of Orofacial Pain and Jaw Function, Faculty of Odontology, Malmo University, Malmö, Sweden.

Objectives: For jaw functional limitations measured by the Jaw Functional Limitation Scale (JFLS), (a) determining prevalence in the Swedish general adult population, (b) investigating the influence of demographic factors and self-reported dental status and (c) deriving normative values.

Methods: A random sample of the general adult population in Sweden was approached (response rate: 46%, N = 1,372). Prevalence was determined for the JFLS summary score and individual items. Read More

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November 2018
4 Reads

Prediction of bleeding by thromboelastography in ICU patients with haematological malignancy and severe sepsis.

Blood Coagul Fibrinolysis 2018 Dec;29(8):683-688

Department of Intensive Care 4131, Copenhagen University Hospital, Rigshospitalet.

: ICU patients with haematological malignancy have an increased risk of bleeding. Recently, global haemostatic methods such as thromboelastography (TEG) have gained impact in evaluating coagulation. The aim of this study was to observe whether TEG could predict bleeding in haematological ICU patients with severe sepsis. Read More

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December 2018
10 Reads

Health-Related Quality of Life 5 Years After Roux-en-Y Gastric Bypass in Young (18-25 Years) Versus Older (≥ 26 Years) Adults: a Scandinavian Obesity Surgery Registry Study.

Obes Surg 2018 Nov 13. Epub 2018 Nov 13.

Swedish School of Sports and Health Sciences, Stockholm, Sweden.

Background: To compare changes in health-related quality of life (HRQoL) in young (18-25 years) versus older (≥ 26 years) adults up to 5 years after Roux-en-Y gastric bypass (RYGB).

Methods: Data on Short Form-36 (SF-36) and obesity-related problems scale (OP) at baseline and 1, 2, and 5 years after RYGB were extracted from the Scandinavian Obesity Surgery Registry. Within-group changes and the effect of age group on 5-year changes in SF-36 and OP were analyzed. Read More

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November 2018
6 Reads

The impact of childhood bullying on the daily lives of Nordic children and young adolescents.

Acta Paediatr 2018 Nov 13. Epub 2018 Nov 13.

Section for General Medical Practice, Department of Public Health, Aarhus University, Aarhus C, Denmark.

Aim: Childhood bullying may negatively affect the mental health in children and adolescents, but few studies have explored this potential link. We aimed to investigate the association between childhood bullying and the impact of poor mental health on the daily life in a population of Nordic children and adolescents aged 5-16 years.

Methods: This cross-sectional study was based on data from the Nordic survey on Children's Health and Wellbeing (NordChild) from 2011. Read More

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November 2018
4 Reads

Bariatric Surgery Worldwide: Baseline Demographic Description and One-Year Outcomes from the Fourth IFSO Global Registry Report 2018.

Obes Surg 2018 Nov 12. Epub 2018 Nov 12.

Department of Bariatric Surgery, AZ Sint Blasius Medical Center, Dendermonde, Belgium.

Background: Since 2014, the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) has produced an annual report of all bariatric surgery submitted to the Global Registry. We describe baseline demographics of international practice from the 4th report.

Methods: The IFSO Global Registry amalgamated data from 51 different countries, 14 of which provided data from their national registries. Read More

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November 2018
6 Reads

Differences between performance of F crossbreds and Holsteins at different production levels.

J Dairy Sci 2018 Nov 8. Epub 2018 Nov 8.

SEGES, Agro Food Park 15, 8200 Aarhus N, Denmark; Department of Molecular Biology and Genetics, Faculty of Science and Technology, Aarhus University, PO Box 50, DK-8830 Tjele, Denmark.

Crossbreeding in dairy cattle has recently become of increased interest. However, farmers in Scandinavian countries are reluctant to implement crossbreeding in their herds, and one reason is the common opinion that only herds at a poor level of management can benefit from crossbreeding. The Danish Cattle Database (SEGES, Aarhus, Denmark) provided data on 14 traits regarding milk yield, udder health, fertility traits, stillbirth, and survival. Read More

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November 2018

Intermediate-term Experience With the STAR Total Ankle in the United States.

Foot Ankle Int 2018 Nov 9:1071100718808743. Epub 2018 Nov 9.

3 Division of Foot & Ankle Surgery, Florida Orthopaedic Institute, Tampa, FL, USA.

Background:: Limited intermediate and no real long-term follow-up data have been published for total ankle arthroplasty (TAA) in the United States. This is a report of clinical follow-up data of a prospective, consecutive cohort of patients who underwent TAA by a single surgeon from 1999 to 2013 with the Scandinavian Total Ankle Replacement (STAR) prosthesis.

Methods:: Patients undergoing TAA at a single US institution were enrolled into a prospective study. Read More

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November 2018
5 Reads

Shift work and sex are variants across Karolinska Sleep Questionnaire and the application of linking analysis as a step forward using Item Response Theory.

Chronobiol Int 2018 Nov 7:1-15. Epub 2018 Nov 7.

a School of Public Health , São Paulo University , Brazil.

The frequency of sleep disturbances is considerably higher in the night and shift workers and in females than in day workers and males, respectively. However, a subjective sleep scale must be invariant across these groups, independently of the level of their members on the scale. This study is aimed to test the invariance of the Karolinska Sleep Questionnaire's (KSQ) items by shift work and sex. Read More

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November 2018
6 Reads

Epidemiology of firearm injuries in a Scandinavian trauma center.

Eur J Trauma Emerg Surg 2018 Nov 3. Epub 2018 Nov 3.

Section of Acute and Trauma Surgery, Karolinska University Hospital, Stockholm, Sweden.

Background: There is a concern that civilian gunshot injuries in Europe are increasing but there is a lack of contemporary studies. The purpose of this study was to investigate the current epidemiology and outcome of firearm injuries.

Methods: Retrospective cohort study of all patients (n = 235) treated for firearm injuries admitted to a Scandinavian trauma center between 2005 and 2016. Read More

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November 2018
7 Reads

Changes in nutritional routines at discharge in Scandinavia during a 10-year period: A follow-up survey.

Clin Nutr ESPEN 2018 Dec 5;28:148-152. Epub 2018 Sep 5.

Center for Nutrition and Bowel Disease, Aalborg University Hospital, Clinical Institute, Aalborg University, Aalborg, Denmark.

Background And Aims: Time to treat malnutrition during hospital admission is limited due to short hospital stays. Therefore, nutritional care often needs to be continued after discharge from hospital. However, health care professionals' attitudes and discharge routines may not always support continuity of good nutritional practice. Read More

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December 2018
6 Reads

Bilingualism and working memory performance: Evidence from a large-scale online study.

PLoS One 2018 2;13(11):e0205916. Epub 2018 Nov 2.

Department of Psychology, Åbo Akademi University, Turku, Finland.

The bilingual executive advantage (BEA) hypothesis has attracted considerable research interest, but the findings are inconclusive. We addressed this issue in the domain of working memory (WM), as more complex WM tasks have been underrepresented in the previous literature. First, we compared early and late bilingual vs. Read More

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November 2018

Substantial changes in the depth distributions of benthic invertebrates in the eastern Kattegat since the 1880s.

Ecol Evol 2018 Sep 29;8(18):9426-9438. Epub 2018 Aug 29.

EcoWorks AB Ellös Sweden.

Bottom trawling and eutrophication are well known for their impacts on the marine benthic environment in the last decades. Evaluating the effects of these pressures is often restricted to contemporary benthic data, limiting the potential to observe change from an earlier (preimpact) state. In this study, we compared benthic species records from 1884 to 1886 by CGJ Petersen with recent data to investigate how benthic invertebrate species in the eastern Kattegat have changed since preimpact time. Read More

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September 2018
6 Reads

Lung transplantation after ex vivo lung perfusion in two Scandinavian centres.

Eur J Cardiothorac Surg 2018 Oct 29. Epub 2018 Oct 29.

Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden.

Objectives: We reviewed our combined clinical outcome in patients who underwent lung transplantation after ex vivo lung perfusion (EVLP) and compared it to the contemporary control group.

Methods: At 2 Scandinavian centres, lungs from brain-dead donors, not accepted for donation but with potential for improvement, were subjected to EVLP (n = 61) and were transplanted if predefined criteria were met. Transplantation outcome was compared with that of the contemporary control group consisting of patients (n = 271) who were transplanted with conventional donor lungs. Read More

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October 2018
3 Reads

Long-Term Safety of Intraperitoneal Radio Transmitter Implants in Brown Bears ().

Front Vet Sci 2018 15;5:252. Epub 2018 Oct 15.

Norwegian Institute for Nature Research, Trondheim, Norway.

Intraperitoneal radio transmitters have been widely used in free-ranging wild mammals, but there are no long-term studies on their biocompatibility or technical stability within the abdominal cavity of animals. Possible negative health effects may bias results from ecological studies on instrumented animals and raise concerns over animal welfare issues. The aim of this study was to evaluate the long-term technical stability and pathological effects of Telonics intraperitoneal very high frequency (VHF) radio transmitters in brown bears (). Read More

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October 2018
5 Reads

Comparing Swedish Foundations: A Carefully Negotiated Space of Existence.

Am Behav Sci 2018 Nov 20;62(13):1889-1918. Epub 2018 May 20.

Stockholm School of Economics, Stockholm, Sweden.

Foundations and philanthropy currently play a very limited role in the Swedish welfare. The same is true in fields like Culture and Recreation or International Activities. Only in the case of funding of research do Swedish foundations exhibit a role possible to define in terms of substitution rather than weak complementarity in relation to government. Read More

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November 2018

Disequilibrium, Adaptation, and the Norse Settlement of Greenland.

Hum Ecol Interdiscip J 2018 10;46(5):665-684. Epub 2018 Sep 10.

6School of Geography and Sustainable Development, Irvine Building, University of St Andrews, St Andrews, KY16 9AL UK.

There is increasing evidence to suggest that arctic cultures and ecosystems have followed non-linear responses to climate change. Norse Scandinavian farmers introduced agriculture to sub-arctic Greenland in the late tenth century, creating synanthropic landscapes and utilising seasonally abundant marine and terrestrial resources. Using a niche-construction framework and data from recent survey work, studies of diet, and regional-scale climate proxies we examine the potential mismatch between this imported agricultural niche and the constraints of the environment from the tenth to the fifteenth centuries. Read More

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September 2018
1 Read

Effect of Everolimus Initiation and Calcineurin Inhibitor Elimination on Cardiac Allograft Vasculopathy in De Novo Heart Transplant Recipients.

Circ Heart Fail 2018 Sep;11(9):e004050

Department of Cardiology, Oslo University Hospital, Rikshospitalet, Norway (S.A., A.K.A., E.G., L.G.).

Background Cardiac allograft vasculopathy (CAV) limits survival after heart transplantation, and the effect of different immunosuppressive regimens on CAV is not fully understood. The randomized SCHEDULE trial (Scandinavian Heart Transplant Everolimus De Novo Study With Early Calcineurin Inhibitors Avoidance) evaluated whether initiation of the proliferation signal inhibitor everolimus and early cyclosporine elimination can reduce CAV development. Methods and Results The SCHEDULE trial was a multicenter Scandinavian trial, where 115 de novo heart transplantation recipients were randomized to everolimus with complete cyclosporine withdrawal 7 to 11 weeks after heart transplantation or standard cyclosporine-based immunosuppression. Read More

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September 2018
5 Reads

Impact of the World Health Organization Pain Treatment Guidelines and the European Medicines Agency Safety Recommendations on Nonsteroidal Anti-Inflammatory Drug Use in Lithuania: An Observational Study.

Medicina (Kaunas) 2018 May 11;54(2). Epub 2018 May 11.

Division of Clinical Pharmacology, Institute of Physiology and Pharmacology, Medical Academy, Lithuanian University of Health Sciences, 44307 Kaunas, Lithuania.

Irrational use of nonsteroidal anti-inflammatory drugs (NSAIDs) is the main cause of adverse effects-associated hospitalizations among all medication groups leading to extremely increased costs for health care. Pharmacoepidemiological studies can partly reveal such issues and encourage further decisions. Therefore, the aim of our study was to evaluate the utilization of non-opioid analgesics (ATC classification N02B and M01A) in Lithuania, and to compare it with that of other Baltic and Scandinavian countries in terms of compliance to the WHO pain treatment guidelines and the EMA safety recommendations on NSAID use. Read More

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May 2018
5 Reads

Quantitative and qualitative assessment of sensory changes induced by local anesthetics block of two different trigeminal nerve branches.

Clin Oral Investig 2018 Oct 16. Epub 2018 Oct 16.

Section of Orofacial Pain and Jaw Function, Department of Dentistry and Oral Health, Aarhus University, Vennelyst Boulevard 9, DK-8000, Aarhus, Denmark.

Objectives: The aims were to use different techniques to assess the degree of sensory changes and magnitude of perceived size changes in the facial region induced by nerve blocks of two different trigeminal nerve branches in healthy participants.

Materials And Methods: This placebo-controlled study included 30 healthy volunteers. The participants underwent quantitative and qualitative sensory testing (QST and QualST) thrice: before, 10 min, and 2 h after mental (n = 15) and infraorbital (n = 15) nerve blocks and during control (saline) sessions. Read More

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October 2018
3 Reads

Short interpregnancy interval and poor fetal growth: Evaluating the role of pregnancy intention.

Paediatr Perinat Epidemiol 2018 Oct 16. Epub 2018 Oct 16.

Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada.

Background: Previous studies have demonstrated that short interpregnancy interval (the interval between delivery and estimated last menstrual period of a subsequent pregnancy) is associated with small for gestational age birth. It is controversial if this association is causal, as few studies have accounted for likely confounding factors such as unintended pregnancy. We examined the association between interpregnancy interval and infant birthweight, adjusting for pregnancy intention and other socio-economic and obstetrical risk factors. Read More

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October 2018
12 Reads

Indications for fluid resuscitation in patients with septic shock: Post-hoc analyses of the CLASSIC trial.

Acta Anaesthesiol Scand 2018 Oct 14. Epub 2018 Oct 14.

Department of Intensive Care, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

Background: Fluid resuscitation is recommended in septic shock, but the specific indications for fluids have not been established. Our aim was to investigate the indications currently used for fluid resuscitation and the effect of fluid on these indications in patients with septic shock admitted to the intensive care unit (ICU).

Methods: This was a post-hoc analysis of the CLASSIC trial, where patients with septic shock were randomized to fluid restriction or standard care. Read More

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October 2018
3 Reads

Discovery of the first pincer wasp (Hymenoptera, Dryinidae) from Rovno amber.

Zootaxa 2018 Aug 8;4457(2):296-304. Epub 2018 Aug 8.

Schmalhausen Institute of Zoology, National Academy of Sciences of Ukraine, B. Khmelnitsky 15, Kiev, 01601, Ukraine..

Dryinidae (Hymenoptera: Chrysidoidea) are recorded for the first time from Rovno amber (Ukraine), following the discovery of one female of Dryinus janzeni Olmi. Holotypes of D. balticus (Olmi) and D. Read More

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August 2018
1 Read

Significantly lower CYP2D6 metabolism measured as the O/N-desmethylvenlafaxine metabolic ratio in carriers of CYP2D6*41 versus CYP2D6*9 or CYP2D6*10: a study on therapeutic drug monitoring data from 1003 genotyped Scandinavian patients.

Br J Clin Pharmacol 2018 Oct 12. Epub 2018 Oct 12.

Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.

Aims: CYP2D6*9, CYP2D6*10 and CYP2D6*41 are the most frequent reduced-function CYP2D6 alleles in Caucasians. Despite lacking in vivo evidence, they are collectively classified with an enzyme activity score of 0.5. Read More

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October 2018
4 Reads

External validation of the Scandinavian guidelines for management of minimal, mild and moderate head injuries in children.

BMC Med 2018 10 12;16(1):176. Epub 2018 Oct 12.

Department of Emergency Medicine, Royal Children's Hospital, 50 Flemington Rd, Parkville, Victoria, 3052, Australia.

Background: Clinical decision rules (CDRs) aid in the management of children with traumatic brain injury (TBI). Recently, the Scandinavian Neurotrauma Committee (SNC) has published practical, evidence-based guidelines for children with Glasgow Coma Scale (GCS) scores of 9-15. This study aims to validate these guidelines and to compare them with other CDRs. Read More

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October 2018
9 Reads

What is happening to laboratory medicine in Denmark?

Authors:
Per E Jørgensen

Clin Chem Lab Med 2018 Oct 11. Epub 2018 Oct 11.

Management Board, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 København Ø, Denmark.

A number of current trends will affect and probably change laboratory medicine, as we know it. Scientific and technological developments, digital health with big data and artificial intelligence, and centralization will change the interfaces among the specialties of laboratory medicine. They might even challenge the identity of some specialties. Read More

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October 2018
1 Read

The effect of surgery on fat mass, lipid and glucose metabolism in mild primary hyperparathyroidism

Endocr Connect 2018 08 1;7(8):941-948. Epub 2018 Aug 1.

Section of Specialized Endocrinology, Oslo University Hospital, Oslo, Norway

Context: Mild primary hyperparathyroidism has been associated with increased body fat mass and unfavorable cardiovascular risk factors.

Objective: To assess the effect of parathyroidectomy on fat mass, glucose and lipid metabolism.

Design, Patients, Interventions, Main Outcome Measures: 119 patients previously randomized to observation (OBS; n = 58) or parathyroidectomy (PTX; n = 61) within the Scandinavian Investigation of Primary Hyperparathyroidism (SIPH) trial, an open randomized multicenter study, were included. Read More

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August 2018
2 Reads

Survival of Listeria monocytogenes during in vitro gastrointestinal digestion after exposure to 5 and 0.5 % sodium chloride.

Food Microbiol 2019 Feb 23;77:78-84. Epub 2018 Aug 23.

Norwegian University of Life Sciences, Campus Adamstuen, Ullevålsveien 72, 0454, Oslo, Norway.

The food industry is under pressure to reduce the NaCl content in food, but the consequences on the ability of L. monocytogenes to survive in the human host and cause listeriosis is not known. In this study, a recently developed internationally harmonized static in vitro digestion (IVD) model was used to investigate the survival of L. Read More

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February 2019
4 Reads

Psychosocial consequences among women with false-positive results after mammography screening in Norway.

Scand J Prim Health Care 2018 Dec 8;36(4):380-389. Epub 2018 Oct 8.

b The Research Unit for General Practice and Section of General Practice, Department of Public Health , University of Copenhagen , Copenhagen , Denmark.

Background: Mammography screening may cause psychosocial harm for women experiencing a false-positive screening result. Previous studies suggest long-term consequences. The aim of the present study was to assess psychosocial consequences of false-positive findings on screening mammography within a six month follow-up. Read More

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December 2018
2 Reads

A mixture of Persistent Organic Pollutants (POPs) and Azoxymethane (AOM) show potential synergistic effects on intestinal tumorigenesis in the A/J Min/+ mouse model.

Chemosphere 2019 Jan 24;214:534-542. Epub 2018 Sep 24.

Section for Experimental Biomedicine, Department of Production Animal Clinical Sciences, Norwegian University of Life Sciences, Norway.

A multitude of cancer types, including breast, testicular, liver and colorectal cancer, have associations with exposure to Persistent Organic Pollutants (POPs). The present study aimed to investigate whether a mixture of POPs could affect intestinal tumorigenesis in the A/J Min/+ mouse, a model for human colorectal cancer (CRC). Pollutants were selected for their presence in Scandinavian food products and the mixture was designed based on defined human estimated daily intake levels. Read More

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January 2019
3 Reads

Lost in digitalization? Municipality employment of welfare technologies.

Authors:
Susanne Frennert

Disabil Rehabil Assist Technol 2018 Sep 28:1-8. Epub 2018 Sep 28.

a Department of Technology in Health Care , KTH Royal Institute of Technology School of Chemistry, Biotechnology, and Health , Huddinge , Sweden.

Introduction: Swedish municipalities face a number of daunting challenges; an aging population, the public's increased demands and expectations on municipality services, and a strained economy to mention some. Welfare technology, a Scandinavian concept launched to promote digitalization, is seen as one solution to meet these challenges.

Objective: Despite these promises, few welfare technology applications are offered by local Swedish municipalities and care organizations. Read More

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September 2018
8 Reads

Alert, Eyes-Open Sport Hypnosis.

Am J Clin Hypn 2018 Oct;61(2):159-172

a Örebro University , Sweden.

Sport hypnosis (SH) is a form of alert hypnosis defined by mental training procedures based on three techniques in combination: eyes-open hypnosis, traditional eyes-closed hypnosis, and self-hypnosis. The self-hypnotic state is operationally defined as the imagined "inner mental room" (IMR). The main purpose of SH is to produce the sport hypnotic state (SHS), or the flow state, a form of alert hypnosis. Read More

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October 2018
6 Reads

Delivery outcomes in term births after bariatric surgery: Population-based matched cohort study.

PLoS Med 2018 Sep 26;15(9):e1002656. Epub 2018 Sep 26.

Department of Medicine, Solna, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden.

Background: Obesity increases the risk of adverse delivery outcomes. Whether weight loss induced by bariatric surgery influences these risks remains to be determined. The objective was to investigate the risk of adverse delivery outcomes among post-surgery women compared with women without bariatric surgery history but with similar characteristics. Read More

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September 2018
7 Reads

Is there consensus regarding surgical treatment of bone sarcomas?

World J Orthop 2018 Sep 18;9(9):173-179. Epub 2018 Sep 18.

Department of Orthopaedic Oncology, Aarhus University Hospital, Aarhus C8000, Denmark.

Aim: To perform an Internet based survey on the surgical management of bone sarcomas in the lower extremity amongst sarcoma surgeons.

Methods: All orthopedic surgical members of the Scandinavian Sarcoma Group were invited to participate in an online questionnaire. The questionnaire consisted of a clinical case involving resection of a malignant bone tumor. Read More

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September 2018
4 Reads