10,019 results match your criteria Scandinavian Journal of Gastroenterology[Journal]


Analysis of risk factors of gastrointestinal stromal tumors in different age groups based on SEER database.

Scand J Gastroenterol 2019 Apr 24:1-5. Epub 2019 Apr 24.

a Department of General Surgery , The First Affiliated Hospital of Harbin Medical University , Harbin , PR China.

Objective: To investigate the risk factors affecting the survival of patients with gastrointestinal stromal tumors (GISTs) in different age groups.

Methods: Information on 6089 GIST patients was screened from the Surveillance, Epidemiology, and End Results (SEER) database. Risk factor analysis was performed using a chi-square test (univariate analysis). Read More

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http://dx.doi.org/10.1080/00365521.2019.1604798DOI Listing

Repeat capsule endoscopy in suspected gastrointestinal bleeding.

Scand J Gastroenterol 2019 Apr 24:1-6. Epub 2019 Apr 24.

a Department of Gastroenterology , Royal Infirmary of Edinburgh , Edinburgh , Scotland.

Objectives: This study aims to review the utility of repeat capsule endoscopy (CE) with on-going concern of small bowel (SB) bleeding following initial SB investigation with CE.

Materials And Methods: A specifically designed database of CE examinations performed over 13 years, with hospital records, was retrospectively interrogated for patients undergoing multiple CEs to investigate iron deficiency anaemia (IDA) or suspected SB bleeding.

Results: 1335/2276 (58. Read More

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http://dx.doi.org/10.1080/00365521.2019.1606932DOI Listing

Evaluation of fatigue in inflammatory bowel disease - a useful tool in daily practice.

Scand J Gastroenterol 2019 Apr 23:1-6. Epub 2019 Apr 23.

a Department of Gastroenterology , Instituto Português de Oncologia de Lisboa Francisco Gentil E.P.E. (IPOLFG) , Lisbon , Portugal.

Background: Fatigue is a common symptom reported in inflammatory bowel disease (IBD) patients. It can be severe and modify the self-perception of disease.

Objective: To evaluate the contribution of clinical and demographic factors to the level of fatigue in IBD patients. Read More

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http://dx.doi.org/10.1080/00365521.2019.1602669DOI Listing

An altered composition of the microbiome in microscopic colitis is driven towards the composition in healthy controls by treatment with budesonide.

Scand J Gastroenterol 2019 Apr 22:1-7. Epub 2019 Apr 22.

a Department of Medicine , Section of Gastroenterology, Zealand University Hospital , Køge , Denmark.

Background And Aim: Microscopic colitis (MC) is an inflammatory disease of the bowel, hypothetically induced by an immunologic response to a luminal microbial agent. We aimed to characterize the microbiome composition in MC and subtypes collagenous colitis (CC) and lymphocytic colitis (LC) and to identify a possible microbial effect of treatment.

Method: Stool samples were collected from MC patients prior to treatment, at 8 weeks (during treatment) and at 16 weeks (after treatment), and from healthy controls, not receiving treatment, at matched time-points. Read More

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http://dx.doi.org/10.1080/00365521.2019.1599064DOI Listing

The high mortality of patients with common variable immunodeficiency and small bowel villous atrophy.

Scand J Gastroenterol 2019 Apr 21:1-5. Epub 2019 Apr 21.

a Coeliac Centre/First Department of Internal Medicine , Fondazione IRCCS Policlinico San Matteo University of Pavia , Pavia , Italy.

Objectives: Common variable immunodeficiency (CVID) is a primary humoral immunodeficiency characterised by reduced serum levels of immunoglobulins, recurrent infections, autoimmune phenomena and lymphoproliferative disorders. Gastrointestinal symptoms are very common in these patients and a coeliac-like villous atrophy was described in some of them. Since mortality in CVID is much higher than in the general population, our aim was to evaluate mortality rates and clinical predictors of survival in patients with both CVID and duodenal villous atrophy. Read More

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http://dx.doi.org/10.1080/00365521.2019.1568543DOI Listing

Characteristics and risk factors for recurrence of nonalcoholic steatohepatitis following liver transplantation.

Scand J Gastroenterol 2019 Apr 18:1-7. Epub 2019 Apr 18.

a Department of Clinical Science, Intervention and Technology, Division of Transplantation Surgery , Karolinska Institutet , Stockholm , Sweden.

Objectives: Nonalcoholic steatohepatitis (NASH), which is a common and increasing indication for liver transplantation (LT), is known to recur after LT. Since the recurrence of NASH can lead to graft failure, the identification of predictive factors is needed and preventive strategies should be implemented.

Methods: We retrospectively examined 95 patients who had undergone LT for NASH or alcoholic liver disease (ALD) as a primary indication. Read More

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http://dx.doi.org/10.1080/00365521.2019.1577484DOI Listing
April 2019
1 Read

Granulocyte-monocyte apheresis: an alternative combination therapy after loss of response to anti-TNF agents in ulcerative colitis.

Scand J Gastroenterol 2019 Apr 14:1-6. Epub 2019 Apr 14.

a Gastroenterology Department , Hospital de Galdakao , Galdakao , Spain.

Objective: To evaluate the effectiveness and safety of the combination of granulocyte-monocyte apheresis (GMA) after loss of response (LOR) to anti-tumor necrosis factor (TNF) agents in ulcerative colitis (UC).

Materials And Methods: A retrospective, multicenter study was performed in 11 inflammatory bowel disease (IBD) Units. Clinical remission was defined as a partial Mayo score ≤2. Read More

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https://www.tandfonline.com/doi/full/10.1080/00365521.2019.1
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http://dx.doi.org/10.1080/00365521.2019.1600715DOI Listing
April 2019
5 Reads

Age and cystic size are associated with clinical impact of endoscopic ultrasonography-guided fine-needle aspiration on the management of pancreatic cystic neoplasms.

Scand J Gastroenterol 2019 Apr 12:1-7. Epub 2019 Apr 12.

e Department of Laboratory Medicine , College of Medicine, National Taiwan University , Taipei , Taiwan.

Objectives: The clinical impact of endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA) in managing pancreatic cystic neoplasms (PCNs) remains controversial. The aim of this study was to identify which patients with PCNs would benefit from EUS-FNA.

Methods: A retrospective study was performed on patients with PCNs who underwent EUS-FNA between January 2009 and June 2018. Read More

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http://dx.doi.org/10.1080/00365521.2019.1601254DOI Listing
April 2019
1 Read

Data quality and colonoscopy performance indicators in the prevalent round of a FIT-based colorectal cancer screening program.

Scand J Gastroenterol 2019 Apr 12:1-7. Epub 2019 Apr 12.

a Department of Public Health Programmes , Randers Regional Hospital , Randers , Denmark.

Objective: From the prevalent round of the Danish FIT-based colorectal cancer (CRC) screening program, we aimed (i) to evaluate the quality of recorded data and (ii) to characterize the colonoscopies by measuring variation in performance indicators between colonoscopists and assessing the ratio between adenoma detection rate (ADR) and polyp detection rate (PDR).

Materials And Methods: This study included screening colonoscopies performed in Central Denmark Region within 60 days of a positive FIT-result from 1 July 2015 through 30 June 2017. The participants were the colonoscopists, performing these procedures. Read More

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http://dx.doi.org/10.1080/00365521.2019.1597158DOI Listing
April 2019
5 Reads

Response to letter to the editor: 'Outcome of peroral endoscopic myotomy (POEM) in treatment-naive patients. A systematic review'.

Scand J Gastroenterol 2019 Apr 12. Epub 2019 Apr 12.

a Department of Gastroenterology , Oslo University Hospital , Oslo , Norway.

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http://dx.doi.org/10.1080/00365521.2019.1599416DOI Listing

Comment on: 'Outcome of peroral endoscopic myotomy (POEM) in treatment-naive patients. A systematic review'.

Scand J Gastroenterol 2019 Apr 4. Epub 2019 Apr 4.

a Department of Gastroenterology , Affiliated Hospital of Southwest Medical University , Luzhou , PR China.

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http://dx.doi.org/10.1080/00365521.2019.1599415DOI Listing
April 2019
1 Read

Multidonor FMT capsules improve symptoms and decrease fecal calprotectin in ulcerative colitis patients while treated - an open-label pilot study.

Scand J Gastroenterol 2019 Apr 4:1-8. Epub 2019 Apr 4.

b Department of Gastroenterology , Aleris-Hamlet Hospitals Copenhagen , Soeborg , Denmark.

Background: Growing evidence indicates that gut dysbiosis is a factor in the pathogenesis of ulcerative colitis (UC). Fecal microbiota transplantation (FMT) appears to be promising in inducing UC remission, but there are no reports regarding administration using capsules.

Methods: Seven patients with active UC, aged 27-50 years, were treated with 25 multidonor FMT capsules daily for 50 days as a supplement to their standard treatment in an open-label pilot study. Read More

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http://dx.doi.org/10.1080/00365521.2019.1585939DOI Listing

Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.

Scand J Gastroenterol 2019 Apr 4:1-9. Epub 2019 Apr 4.

a Department of Gastroenterology , Third Xiangya Hospital, Central South University , Changsha , China.

Objective: Levels of oncostatin M (OSM) and the composition of gut microbiota predict responses to anti-TNF agents used for IBD therapy. Here, the aim was to investigate the effects of Roseburia intestinalis, a gut microbiota, on OSM and on intestinal barrier in colitis.

Methods: In the murine model of 3% dextran sulfate sodium (DSS)-induced colitis, we tested disease activity index (DAI), colon length, histological score and expression of tight junction (TJ) proteins (ZO-1, occludin and claudin-1), OSM, TNF-α and TLR5. Read More

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http://dx.doi.org/10.1080/00365521.2019.1595708DOI Listing
April 2019
1 Read
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Unchanged mortality in patients with acute cholangitis despite an increase in malignant etiologies - a 25-year epidemiological study.

Scand J Gastroenterol 2019 Apr 4:1-7. Epub 2019 Apr 4.

a Department of Medical Gastroenterology S , Odense University Hospital , Odense , Denmark.

Background And Aims: Acute cholangitis (AC) is a rare but serious condition, with an incidence of 7.0 per 10,000 people and mortality rates up to 10%. The aim of this study was to describe changes in obstruction etiology, comorbidities, clinical factors, and mortality among AC patients during a 25-year period. Read More

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http://dx.doi.org/10.1080/00365521.2019.1585568DOI Listing
April 2019
1 Read

The relationship between gastric microbiota and gastric disease.

Scand J Gastroenterol 2019 Apr 4:1-6. Epub 2019 Apr 4.

a Endoscopy Center, Tianjin Union Medical Center , Tianjin , China.

Traditionally, the stomach was believed to be a sterile organ unsuitable for microbiota growth. However, the discovery of H. pylori subverted this conception. Read More

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http://dx.doi.org/10.1080/00365521.2019.1591499DOI Listing
April 2019
4 Reads

Dual biological therapy with anti-TNF, vedolizumab or ustekinumab in inflammatory bowel disease: a systematic review with pool analysis.

Scand J Gastroenterol 2019 Apr 4:1-7. Epub 2019 Apr 4.

b Molinette Hospital, Unit of Gastroenterology , Turin , Italy.

Background: Inflammatory bowel diseases patients eligible for biological therapy represent a group with considerable disease burden and biologics only achieve 40% clinical remission rates in responders after 1 year of therapy.

Aims: To collect all the published data about patients treated with dual biological therapy with an Anti-TNF, vedolizumab or ustekinumab, for a period of at least 3 months and to pool the data about the effectiveness and safety.

Methods: A MEDLINE, and Web of Science search of all studies published in English until 1 January 2019 was conducted. Read More

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http://dx.doi.org/10.1080/00365521.2019.1597159DOI Listing
April 2019
1 Read

Correlation and concordance measures between clinical, endoscopic and histological scores activity in Crohn's disease under treatment.

Scand J Gastroenterol 2019 Apr 3:1-5. Epub 2019 Apr 3.

e Pathology Department , Hospital de Base do Distrito Federal , Brasília , Brazil.

Aim: Our aim was to evaluate the correlation and concordance measures between clinical, endoscopic and histologic remission in Crohn's disease (CD) under treatment.

Method: Twenty-four patients with CD under treatment were included in a prospective consecutive cross-sectional study from January to September 2018. Clinical activity was assessed by Crohn's Disease Activity Index (CDAI). Read More

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http://dx.doi.org/10.1080/00365521.2019.1596305DOI Listing
April 2019
1 Read

Factors related to paradoxical reactions during propofol-induced sedated endoscopy.

Scand J Gastroenterol 2019 Mar 31:1-6. Epub 2019 Mar 31.

b Center for Health Promotion and Endoscopy, Wonkwang University School of Medicine , Gunpo , South Korea.

Objective: The factors related to paradoxical excitement during propofol-induced sedation remain unclear. We aimed to investigate this issue during sedated upper endoscopy.

Material And Methods: Among the health examinees scheduled for sedated upper endoscopy from June 2017 to December 2017, 421 participated in the study. Read More

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http://dx.doi.org/10.1080/00365521.2019.1585938DOI Listing
March 2019
1 Read

Efficacy and safety of submucosal tunneling endoscopic resection for upper gastrointestinal submucosal tumors with more than 1-year' follow-up: a systematic review and meta-analysis.

Scand J Gastroenterol 2019 Mar 29:1-10. Epub 2019 Mar 29.

a Department of Gastroenterology , Affiliated Hospital of Southwest Medical University , Luzhou , China.

Objectives: Submucosal tunneling endoscopic resection (STER) is a novel therapeutic approach for upper gastrointestinal submucosal tumors (SMTs) especially for tumors originating from the muscularis propria layer. Presently, several studies have reported the efficacy and safety of STER for SMTs. Therefore, we conducted this study to review the clinical outcomes of STER with more than 1-year' follow-up duration. Read More

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http://dx.doi.org/10.1080/00365521.2019.1591500DOI Listing

Minimally invasive assessment of hepatic function in children with indocyanine green elimination: a validation study.

Scand J Gastroenterol 2019 Mar 29:1-7. Epub 2019 Mar 29.

e Department of Clinical Physiology, Nuclear Medicine and PET , Copenhagen University Hospital, Rigshospitalet , Copenhagen Ø , Denmark.

Objectives: Pediatric liver disease (PLD) covers a variety of etiologies and severities, from mild temporary illness to diseases with fatal outcomes. There is a demand for minimally invasive and reliable measures for assessment of the severity of PLD. Indocyanine green (ICG) elimination kinetics to estimate hepatic function has been used in adults for decades, however, due to invasiveness, the use in PLD is still limited. Read More

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http://dx.doi.org/10.1080/00365521.2019.1591497DOI Listing
March 2019
1 Read

TRIM2 is a novel promoter of human colorectal cancer.

Scand J Gastroenterol 2019 Mar 27:1-9. Epub 2019 Mar 27.

d Precise Genome Engineering Center, School of Life Sciences , Guangzhou University , Guangzhou , China.

Objectives: The incidence of colorectal cancer (CRC) is increasing year by year and appears to be younger, due to the low early diagnosis rate and metastasis. It is difficult to remedy by conventional treatment. Here, we reported that tripartite motif containing protein 2 (TRIM2) could promote tumor growth, invasion and metastasis of CRC via a mechanism that involved EMT both in vitro and in vivo. Read More

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http://dx.doi.org/10.1080/00365521.2019.1575463DOI Listing

Impact of sclerosing dacryoadenitis/sialadenitis on relapse during steroid therapy in patients with type 1 autoimmune pancreatitis.

Scand J Gastroenterol 2019 Mar 27:1-6. Epub 2019 Mar 27.

a Department of Gastroenterology and Metabolism, Graduate School of Biomedical & Health Sciences , Hiroshima University , Hiroshima , Japan.

Objectives: Steroids are the first-line drugs for induction of remission in patients with type 1 autoimmune pancreatitis (AIP), and the usefulness of steroid maintenance therapy to prevent relapse has recently been reported. However, even during steroid therapy, a relatively large percentage of patients relapse and the predictive factors for relapse have not yet been elucidated. The aim of this study was to clarify the predictive factors for relapse of AIP patients during steroid therapy. Read More

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http://dx.doi.org/10.1080/00365521.2019.1577489DOI Listing
March 2019
2 Reads

Fragmented management of long-term parenteral support for adult intestinal failure in Finland.

Scand J Gastroenterol 2019 Mar 27:1-5. Epub 2019 Mar 27.

c Department of Gastroenterology , Abdominal Center, University of Helsinki and Helsinki University Hospital , Helsinki , Finland.

Objectives: Parenteral support (PS) is the first-line therapy for intestinal failure (IF). Optimal patient outcomes require experienced multidisciplinary teams adhering to structured protocols. As practices to provide long-term PS for adult IF patients in Finland are unknown, this cross-sectional nationwide study aimed to evaluate current management of PS for adult IF across the country. Read More

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http://dx.doi.org/10.1080/00365521.2019.1588370DOI Listing
March 2019
1 Read

Treatment of locally advanced pancreatic cancer with irreversible electroporation - a Danish single center study of safety and feasibility.

Scand J Gastroenterol 2019 Mar 24:1-7. Epub 2019 Mar 24.

a Department of Gastrointestinal Surgery , Aalborg University Hospital , Aalborg , Denmark.

Objectives: Irreversible electroporation (IRE) is a novel non-thermal ablative technique applied in the treatment of unresectable locally advanced pancreatic cancer (LAPC). This paper reports on the initial experience with IRE of unresectable LAPC in our institution.

Methods: From October 2013 to March 2018, patients with unresectable LAPC referred for IRE at the Department of Gastrointestinal Surgery, Aalborg University Hospital, were considered for inclusion in the study. Read More

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https://www.tandfonline.com/doi/full/10.1080/00365521.2019.1
Publisher Site
http://dx.doi.org/10.1080/00365521.2019.1575465DOI Listing
March 2019
5 Reads

Fecal immunochemical test in cancer screening - colonoscopy outcome in FIT positives and negatives.

Scand J Gastroenterol 2019 Mar 23:1-8. Epub 2019 Mar 23.

g Department of Medicine , Solna Karolinska Institutet , Stockholm , Sweden.

Objectives: Fecal immunochemical test (FIT) is used in colorectal cancer (CRC) screening, but evaluations of multiple sample strategies in colonoscopy screening cohorts are rare. The aim of this study was to assess accuracy of FIT for advanced neoplasia (AN) with two fecal samples in a colonoscopy screening cohort.

Materials And Methods: The study comprised 1155 participants of the colonoscopy arm in SCREESCO (Screening of Swedish Colons, NCT02078804), a randomized controlled study on CRC screening of 60-year-olds from the Swedish average-risk population. Read More

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http://dx.doi.org/10.1080/00365521.2019.1585569DOI Listing

Relapse rates and predictors for relapse in a real-life cohort of IBD patients after discontinuation of anti-TNF therapy.

Scand J Gastroenterol 2019 Mar 23:1-8. Epub 2019 Mar 23.

a Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam , Amsterdam , The Netherlands.

Objective: We investigated relapse rates after anti-tumor necrosis factor (anti-TNF) withdrawal in inflammatory bowel disease (IBD) patients, response to restart of anti-TNF treatment and predictors for relapse.

Methods: IBD patients in remission receiving infliximab or adalimumab treatment for ≥1 year who discontinued treatment were included. Relapse rates and predictors for relapse were studied using survival and Cox regression analysis. Read More

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http://dx.doi.org/10.1080/00365521.2019.1582693DOI Listing
March 2019
1 Read

Non-invasive fibrosis scoring systems can predict future metabolic complications and overall mortality in non-alcoholic fatty liver disease (NAFLD).

Scand J Gastroenterol 2019 Mar 23:1-7. Epub 2019 Mar 23.

a Department of Gastroenterology and Hepatology , Skåne University Hospital , Malmö , Sweden.

Background And Aim: Progression to fibrosis in non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of liver-related events, overall mortality and possibly metabolic comorbidities. Our aim was to determine if non-invasive fibrosis scoring systems can predict the future risk of diabetes mellitus, cardiovascular disease (CVD), chronic kidney disease (CKD), liver-related events and overall mortality.

Methods: Patients with biopsy-proven NAFLD 1978 to 2006 were identified from a computerised register in Malmö, Sweden. Read More

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http://dx.doi.org/10.1080/00365521.2019.1583366DOI Listing
March 2019
1 Read

Hepatitis C virus (HCV) related liver fibrosis in people who inject drugs (PWID) at the Stockholm Needle Exchange - evaluated with liver elasticity.

Scand J Gastroenterol 2019 Mar 23:1-9. Epub 2019 Mar 23.

a Department of Medicine Huddinge, Division of Infectious Diseases , Karolinska Institutet, Karolinska University Hospital Huddinge , Stockholm , Sweden.

Background And Aims: Sharing of unsterile injection equipment among people who inject drugs (PWID) is the major transmission-route for hepatitis C (HCV). HCV is highly prevalent in PWID in the Stockholm needle exchange programme (NEP). The frequency of advanced liver fibrosis among the participants is, however, unknown. Read More

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http://dx.doi.org/10.1080/00365521.2019.1580764DOI Listing

Blood platelet function abnormalities in cirrhotic patients with esophageal varices in relation to the variceal bleeding history.

Scand J Gastroenterol 2019 Mar 23:1-8. Epub 2019 Mar 23.

a Department of Gastroenterology and Internal Medicine , Medical University of Bialystok , Bialystok , Poland.

Objective: The study aimed at assessing the effect of thrombocytopenia and platelet function abnormalities on the occurrence of variceal bleeding in patients with cirrhosis.

Methods: The results of impedance aggregometry, von Willebrand factor antigen level and thromboelastometry (TEM) with and without the addition of a platelet inhibitor (FIBTEM, EXTEM test, respectively) were compared in two patient groups: Group 1 (n = 32) - patients with moderate or large esophageal or gastric varices, who had never had symptoms of acute gastrointestinal bleeding and Group 2 (n = 26) - patients with history of variceal bleeding.

Results: Standard clotting test indicated more hypocoagulable profile in Group 2 compared to Group 1. Read More

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http://dx.doi.org/10.1080/00365521.2019.1578822DOI Listing
March 2019
2 Reads

Emu Oil reduces disease severity in a mouse model of chronic ulcerative colitis.

Scand J Gastroenterol 2019 Mar 23:1-8. Epub 2019 Mar 23.

a Discipline of Physiology, Adelaide Medical School , The University of Adelaide , Adelaide , South Australia.

Objective: Ulcerative colitis (UC) is characterized by mucosal inflammation and ulceration of the large intestine. Emu Oil (EO) has been reported to protect the intestine against mucositis, NSAID-enteropathy, UC-associated colorectal cancer and acute UC. We aimed to determine whether EO could reduce the severity chronic UC in mice. Read More

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http://dx.doi.org/10.1080/00365521.2019.1581253DOI Listing
March 2019
1 Read

Treatment recommendations for small gastric gastrointestinal stromal tumors: positive endoscopic resection.

Scand J Gastroenterol 2019 Mar 24:1-6. Epub 2019 Mar 24.

a Department of Gastroenterology and Hepatology , General Hospital, Tianjin Medical University , Tianjin , China.

Objectives: To evaluate the safety and efficacy of endoscopic resection and discuss the treatment strategy of small gastric gastrointestinal stromal tumors (GISTs) less than 2 cm.

Material And Methods: The data of 713 patients, who underwent endoscopic submucosal dissection (ESD) for gastric submucosal tumors (SMTs), were retrospectively analyzed. We investigated the clinicopathological features and analyzed the risk potential of small gastric GISTs, and documented therapeutic and follow-up outcomes. Read More

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http://dx.doi.org/10.1080/00365521.2019.1578405DOI Listing

Complications and outcome of percutaneous endoscopic gastrostomy in a high-volume centre.

Scand J Gastroenterol 2019 Mar 24:1-6. Epub 2019 Mar 24.

a Department for Digestive Diseases , Karolinska University Hospital , Stockholm , Sweden.

Introduction: Percutaneous endoscopic gastrostomy (PEG) is the method of choice for long-term enteral feeding for patients with swallowing disorders and normal gut function. There is limited data regarding the demographics and clinical characteristics of patients from whom PEG was removed.

Patients And Methods: We performed a retrospective analysis of all consecutive adult patients who underwent first placement of PEG between 1 August 2013 and 31 December 2015 at Karolinska University Hospital in Stockholm, Sweden. Read More

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http://dx.doi.org/10.1080/00365521.2019.1594354DOI Listing
March 2019
1 Read

Long-term evolution of direct healthcare costs for inflammatory bowel diseases: a population-based study (2006-2015).

Scand J Gastroenterol 2019 Mar 24:1-8. Epub 2019 Mar 24.

a Center for Crohn's and Colitis, Department of Gastroenterology , Kyung Hee University College of Medicine , Seoul , Republic of Korea.

Introduction: We explored the long-term evolution of direct healthcare costs for inflammatory bowel diseases (IBD) using a population-level database in a country with an escalating burden of IBD.

Methods: We searched the database of the Korean National Health Insurance Claims, which covers more than 97% of the South Korean population. An IBD diagnosis was defined as the combination of a billing code for Crohn's disease (CD: K50. Read More

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http://dx.doi.org/10.1080/00365521.2019.1591498DOI Listing
March 2019
1 Read

Fully covered self-expanding metal stents for benign refractory pancreatic duct strictures in chronic pancreatitis.

Scand J Gastroenterol 2019 Mar 24:1-6. Epub 2019 Mar 24.

a Department of Gastroenterological Surgery, Abdominal Center , Helsinki University Hospital and University of Helsinki , Helsinki , Finland.

Background: Pancreatic duct (PD) stricture is a common adverse event in chronic pancreatitis (CP). Primary treatment for refractory PD strictures is endotherapy (ET), including the insertion of multiple plastic stents. In addition, fully covered self-expandable metal stents (FC-SEMSs) have also been successfully used. Read More

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http://dx.doi.org/10.1080/00365521.2019.1588366DOI Listing
March 2019
1 Read

Risk of inflammatory bowel disease after Campylobacter jejuni and Campylobacter concisus infection: a population-based cohort study.

Scand J Gastroenterol 2019 Mar 24:1-8. Epub 2019 Mar 24.

b Department of Clinical Medicine , Aalborg University , Aalborg , Denmark.

Objectives: In this population-based cohort study, we aimed to examine the risk of IBD following a positive stool culture with Campylobacter jejuni or Campylobacter concisus, as well as following culture-negative stool testing.

Materials And Methods: Patients with a first-time positive stool culture with C. jejuni or C. Read More

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http://dx.doi.org/10.1080/00365521.2019.1578406DOI Listing
March 2019
1 Read

Acute pancreatitis in elderly patients: a single-center retrospective evaluation of clinical outcomes.

Scand J Gastroenterol 2019 Mar 24:1-7. Epub 2019 Mar 24.

b Medicina D'Urgenza , Fondazione Policlinico Universitario A. Gemelli IRCCS , Roma, Italia.

Introduction: Acute pancreatitis (AP) incidence in the elderly population has increased in the last years. However, the role of age as influencing factor on the AP clinical course is still debated.

Methods: We reviewed clinical records of consecutive patients admitted with diagnosis of AP. Read More

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http://dx.doi.org/10.1080/00365521.2019.1588369DOI Listing

Near focus NBI endoscopy plus acetic acid for optical polyp characterization in the colorectum - A proof of principle study.

Scand J Gastroenterol 2019 Mar 24:1-7. Epub 2019 Mar 24.

a II. Medizinische Klinik , Klinikum rechts der Isar der TU München, Munich, Germany.

Background And Study Aim: Optical polyp characterization (OPC) in the colorectum is an upcoming challenge for endoscopists. Narrow band imanging (NBI) has been proposed to be helpful for OPC. However, data from clinical studies have shown that quality of OPC differs markedly between endoscopists. Read More

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http://dx.doi.org/10.1080/00365521.2019.1588364DOI Listing

Surgery combined with post-operative trancatheter arterial chemoembolization improves survival of intermediate hepatocellular carcinoma.

Scand J Gastroenterol 2019 Mar 17:1-6. Epub 2019 Mar 17.

a Department of hepato-biliary-pancreatic , Institute of General surgery, Affiliated Hospital of North Sichuan Medical College , Nanchong , P.R. China.

Aim: To investigate the efficacy of surgery combined with post-operative trancatheter arterial chemoembolization (TACE) for intermediate hepatocellular carcinoma (HCC).

Methods: A total of 102 patients were divided into two groups: Radical liver resection only (LR group, 52 patients) and radical liver resection combined with post-operative TACE (combined group, 50 patients). Survival analysis was performed using the Kaplan-Meier method. Read More

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http://dx.doi.org/10.1080/00365521.2019.1577487DOI Listing
March 2019
1 Read

Pancreas divisum and recurrent pancreatitis: long-term results of minor papilla sphincterotomy.

Scand J Gastroenterol 2019 Mar 17:1-6. Epub 2019 Mar 17.

a Digestive Endoscopy Unit, Policlinico Agostino Gemelli Foundation IRCCS , Rome , Italy.

Background And Aims: Pancreas divisum (PD) is the most common congenital variant of the pancreatic ductal system and a potential cause of acute recurrent pancreatitis (ARP). Endoscopic therapy is a therapeutic option for symptomatic PD, but there is limited data on long-term results. We aimed to assess the effect of minor papilla endoscopic sphincterotomy (MiES) in the setting of ARP in patients with PD. Read More

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https://www.tandfonline.com/doi/full/10.1080/00365521.2019.1
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http://dx.doi.org/10.1080/00365521.2019.1584640DOI Listing
March 2019
3 Reads

Low P4HA2 and high PRTN3 expression predicts poor survival in patients with pancreatic cancer.

Scand J Gastroenterol 2019 Mar 17:1-6. Epub 2019 Mar 17.

b Department of Surgery, Clinical Sciences , Lund University and Skåne University Hospital , Lund , Sweden.

Background: The tumor microenvironment in pancreatic cancer has a multifaceted role in disease development and progression. Prolyl 4-hydroxylase subunit alpha 2 (P4HA2) and proteinase 3 (PRTN3) are involved in the synthesis and degradation of collagen in the tumor microenvironment and have been identified as prognostic biomarker candidates for pancreatic cancer in our previous mass spectrometric study. This study aimed at validating prognostic performance of P4HA2 and PRTN3 in a larger cohort of patients. Read More

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http://dx.doi.org/10.1080/00365521.2019.1574360DOI Listing

Application of convolutional neural networks for evaluating Helicobacter pylori infection status on the basis of endoscopic images.

Scand J Gastroenterol 2019 Mar 17:1-6. Epub 2019 Mar 17.

b AI Medical Service , Tokyo , Japan.

Background And Aim: We recently reported the role of artificial intelligence in the diagnosis of Helicobacter pylori (H. pylori) gastritis on the basis of endoscopic images. However, that study included only H. Read More

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https://www.tandfonline.com/doi/full/10.1080/00365521.2019.1
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http://dx.doi.org/10.1080/00365521.2019.1577486DOI Listing
March 2019
5 Reads

Intracellular concentration and transporters in imatinib resistance of gastrointestinal stromal tumor.

Scand J Gastroenterol 2019 Mar 17:1-7. Epub 2019 Mar 17.

a Department of General Surgery , The First Affiliated Hospital of Nanjing Medical University , Nanjing , China.

Background: We aimed to investigate the role of intracellular imatinib concentration in drug resistance and the expression of candidate drug transporters in gastrointestinal stromal tumor (GIST) cell lines.

Method: The imatinib concentrations were measured by the liquid chromatography-tandem mass spectrometry (LC-MS/MS). The expression of candida te drug transporters was detected by qRT-PCR. Read More

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http://dx.doi.org/10.1080/00365521.2019.1577488DOI Listing
March 2019
1 Read
2.329 Impact Factor

Evaluation of liver stiffness by 2D-SWE in combination with non-invasive parameters as predictors for esophageal varices in patients with advanced chronic liver disease.

Scand J Gastroenterol 2019 Mar 17:1-8. Epub 2019 Mar 17.

a Department of Gastroenterology and Gastrointestinal Oncology , University Medical Centre Goettingen , Goettingen , Germany.

Background/aims: Esophageal varices (EV) are common complications in patients with advanced chronic liver disease (ACLD). Non-invasive parameters to exclude EV in patients with ACLD would be desirable. The aim of this study was the evaluation of liver stiffness measurement (LSM) using 2D-shear wave elastography (GE Logiq E9) and other non-invasive parameters as predictors for EV. Read More

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https://www.tandfonline.com/doi/full/10.1080/00365521.2019.1
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http://dx.doi.org/10.1080/00365521.2019.1585571DOI Listing
March 2019
14 Reads

Outcome after iatrogenic esophageal perforation.

Scand J Gastroenterol 2019 Mar 11:1-5. Epub 2019 Mar 11.

c Department of Pediatric and Gastrointestinal Surgery , Oslo University Hospital, Ullevål , Oslo , Norway.

Objectives: Iatrogenic perforations are the most common cause of esophageal perforation. We present our experience mainly based on a non-operative treatment approach as well as long-term outcome in these patients.

Materials And Methods: Twenty-one patients were treated for iatrogenic esophageal perforation at Oslo University Hospital, Ullevål from February 2007 to March 2014. Read More

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https://www.tandfonline.com/doi/full/10.1080/00365521.2019.1
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http://dx.doi.org/10.1080/00365521.2019.1575464DOI Listing
March 2019
7 Reads

Association between proton pump inhibitors therapy and the risk of gastric cancer.

Authors:
Shih-Wei Lai

Scand J Gastroenterol 2019 Mar 11. Epub 2019 Mar 11.

a College of Medicine , China Medical University , Taichung , Taiwan.

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http://dx.doi.org/10.1080/00365521.2019.1583367DOI Listing

Gastric cancer in Latin America.

Scand J Gastroenterol 2019 Mar 8. Epub 2019 Mar 8.

b Department of Biotechnology Chemistry & Pharmacy , University of Siena , Via A. Moro , Siena 53100 , Italy.

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http://dx.doi.org/10.1080/00365521.2019.1577483DOI Listing
March 2019
1 Read

Exercise therapy in patients with constipation: a systematic review and meta-analysis of randomized controlled trials.

Scand J Gastroenterol 2019 Mar 7:1-9. Epub 2019 Mar 7.

a School of Nursing , Jilin University , Changchun , Jilin , China.

Background: Exercise therapy has shown significant efficacy as a means of treating various intestinal diseases, but its role in the treatment of constipation is still unclear. The purpose of this study was thus to analyze the effects of exercise on constipation by means of a systematic review and meta-analysis.

Methods: PubMed, Web of Science, EMBASE, Cochrane Library and three Chinese databases [Wanfang Database, Chinese Biomedical Literature (CBM) and China National Knowledge Infrastructure (CNKI)] were searched for relevant studies published through June 2018. Read More

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http://dx.doi.org/10.1080/00365521.2019.1568544DOI Listing
March 2019
2 Reads
2.329 Impact Factor

Treatment with Noripurum EV is effective and safe in pediatric patients with inflammatory bowel disease and iron deficiency anemia.

Scand J Gastroenterol 2019 Feb 20:1-7. Epub 2019 Feb 20.

a Pediatric Gastroenterology, Pediatric Department , Escola Paulista de Medicina, Universidade Federal de São Paulo , São Paulo , Brasil.

Objectives: To evaluate the therapeutic response and adverse effects of Noripurum EV in children and adolescents with inflammatory bowel disease (IBD) and iron deficiency anemia.

Materials And Methods: Cohort study involving patients with Crohn's disease (CD) and ulcerative colitis (UC) who received treatment for iron deficiency anemia with Noripurum EV. Anemia was defined according to WHO 2011 criteria. Read More

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https://www.tandfonline.com/doi/full/10.1080/00365521.2019.1
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http://dx.doi.org/10.1080/00365521.2019.1570326DOI Listing
February 2019
4 Reads

Collagenous colitis without diarrhoea at diagnosis - a follow up study.

Scand J Gastroenterol 2019 Feb 20:1-4. Epub 2019 Feb 20.

a Department of Medical Sciences , Uppsala University , Uppsala , Sweden.

Objective: Chronic watery diarrhoea is a classical symptom of collagenous colitis (CC). However, in some cases, the typical histologic findings of CC can be found in patients without this symptom. In this study we have performed a follow up on patients with a confirmed histological diagnosis of CC without the typical symptom watery diarrhoea. Read More

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http://dx.doi.org/10.1080/00365521.2019.1570325DOI Listing
February 2019

Incidence of diverticular bleeding: a population-based study.

Scand J Gastroenterol 2019 Feb 10:1-5. Epub 2019 Feb 10.

a Faculty of Medicine , University of Iceland , Reykjavik , Iceland.

Objective: To determine the incidence of diverticular bleeding (DB) and examine the time trend of the incidence. Furthermore to study prognosis with regard to therapy and rebleeding.

Methods: A retrospective, population-based study of patients with DB in a National University Hospital from 2006 to 2016. Read More

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http://dx.doi.org/10.1080/00365521.2019.1566494DOI Listing
February 2019