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Lasers Surg Med 2021 May 11. Epub 2021 May 11.

L'OREAL Research and Innovation, 188, rue Paul Hochart, Chevilly Larue, 94550, France.

Background And Objectives: Low-level light therapies using visible to infrared light are known to activate several cellular functions, such as adenosine triphosphate and nitric oxide synthesis. However, few clinical observations report its biological consequences for skin and scalp homeostasis. Since scalp inflammation was recognized as a potential physiological obstacle to the efficacy of the reference hair regrowth drug Minoxidil in vivo and since perifollicular inflammation is the hallmark of about 50%-70% follicular units in androgenetic alopecia, we decided to investigate whether the anti-inflammatory activity of LLLT/GentleWaves® device were assigned to L'Oréal by Light BioScience L. Read More

BMJ Case Rep 2021 May 10;14(5). Epub 2021 May 10.

Oral and Maxillofacial Surgery, Worcestershire Acute Hospitals NHS Trust, Worcester, UK.

Trichilemmoma is a benign tumour which arises from the hair follicle root sheath, and commonly occurs in the head and neck area. Malignant transformation and locally aggressive growth of these tumours are very rare. Surgical excision remains the mainstay of management, with scarce evidence for other treatment modalities. Read More

Antimicrob Resist Infect Control 2021 May 10;10(1):77. Epub 2021 May 10.

Department of Medical Microbiology, Radboud Centre for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.

Background: Healthcare-associated infections (HAIs) are a significant cause of morbidity and mortality in hospitalized patients. Water in the environment can be a source of infection linked to outbreaks and environmental transmission in hospitals. Water safety in hospitals remains a challenge. Read More

Handchir Mikrochir Plast Chir 2021 May 10. Epub 2021 May 10.

Uniklinik Bonn; Abteilung für Mund-, Kiefer und Plastische Gesichtschirurgie.

Covering huge scalp defects is often a great challenge. Different aspects play a major role in planing and performing the covering of vast defects. We present the case of a patient with a squamous cell carcinoma of the scalp, measuring 8 × 9 centimeters. Read More

J Neurosci Methods 2021 May 7:109220. Epub 2021 May 7.

Department of Neurology, Zucker Hofstra School of Medicine, New York, United States. Electronic address:

Background: Many electroencephalography (EEG) based seizure detection paradigms have been developed and validated over the last two decades. The majority of clinical approaches use scalp or intracranial EEG electrodes. Scalp EEG is limited by patient discomfort and short duration of useful EEG signals. Read More

Int J Neurosci 2021 May 10:1-13. Epub 2021 May 10.

Instituto Nacional de Psiquiatría "Ramón de la Fuente Muñiz", Dirección de Investigaciones en Neurociencias, Laboratorio de Cronobiología y Sueño. CDMX, México.

1. AbstractIntroduction: It has been reported that melatonin diminishes rapid eye movement (REM) sleep latency in patients with Alzheimer's disease (AD). Pharmacological studies suggest that melatonin promotes prompt sleep installation through interaction with GABA receptors, and that it is associated with acute suppression of neural electrical activity. Read More

JAMA Neurol 2021 May 10. Epub 2021 May 10.

Department of Surgery, College of Medical Sciences, Chitwan, Nepal.

Int J Neural Syst 2021 May 7:2150022. Epub 2021 May 7.

Key Laboratory of Measurement and Control of CSE, Ministry of Education, School of Automation, Southeast University, Nanjing 210096, P. R. China.

Epileptic seizure prediction is one of the most used therapeutic adjuvant strategies for drug-resistant epilepsy. Conventional methods usually adopt handcrafted features and manual parameter setting. The over-reliance on the expertise of specialists may lead to weak exploitation of features and low popularization of clinical application. Read More

Indian J Dermatol Venereol Leprol 2021 Apr 23:1-3. Epub 2021 Apr 23.

Kakode Skin Clinic, Margao, Goa, India.

World J Clin Cases 2021 Apr;9(12):2791-2800

Department of Neurosurgery, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041, Guangdong Province, China.

Background: Malignant pheochromocytoma with cerebral and skull metastasis is a very rare disease. Combining our case with 16 previously reported cases identified from a PubMed search, an analysis of 17 cases of malignant cerebral pheochromocytoma was conducted. This literature review aimed to provide information on clinical manifestations, radiographic and histopathological features, and treatment strategies of this condition. Read More

Front Syst Neurosci 2021 16;15:667611. Epub 2021 Apr 16.

Translational Neuroscience Division, Center for Biological Imaging and Neuromodulation, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, United States.

Face recognition is an essential activity of social living, common to many primate species. Underlying processes in the brain have been investigated using various techniques and compared between species. Functional imaging studies have shown face-selective cortical regions and their degree of correspondence across species. Read More

Cleft Palate Craniofac J 2021 May 10:10556656211013168. Epub 2021 May 10.

Department of Plastic and Reconstructive Surgery, Ilsan Paik Hospital, Inje University College of Medicine, Goyang-si, Republic of Korea.

En coup de sabre is an unusual variant of localized scleroderma characterized by its distinct location involving the frontoparietal region of the forehead and scalp. The authors describe a rare case of en coup de sabre in a 3-year-old boy whose disease onset was at 12 months of age. This article presents the clinical manifestations of continuous changes in the lesion photographed over time. Read More

Exp Cell Res 2021 May 6:112618. Epub 2021 May 6.

Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China. Electronic address:

Androgenetic alopecia (AGA) is the most common type of hair loss dysfunction. Secreted frizzled related protein 1 (SFRP1) is found to be associated with hair loss, but its role in AGA and the regulation mechanism of its transcription level is unclear. The aim of our study is to explore the expression of SFRP1 in AGA samples and its transcriptional mechanism. Read More

Trends Neurosci 2021 May 5. Epub 2021 May 5.

Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA; Harvard Medical School, Boston, MA, USA; Department of Neuroscience and Biomedical Engineering, School of Science, Aalto University, Espoo, Finland.

A recent paper by Boto et al. established reliability of noninvasive functional connectivity measurements with a new whole-head optically pumped magnetometer magnetoencephalography (OPM-MEG) system. This rapidly developing technology enables a conformal sensor array to accommodate different head sizes and opens up new avenues for experiments in more naturalistic settings. Read More

J Neurosurg 2021 May 7:1-25. Epub 2021 May 7.

1Machine Intelligence in Clinical Neuroscience (MICN) Laboratory, Department of Neurosurgery, Clinical Neuroscience Center, University Hospital Zurich, University of Zurich, Switzerland.

Objective: Enhanced Recovery After Surgery (ERAS) has led to a paradigm shift in perioperative care through multimodal interventions. Still, ERAS remains a relatively new concept in neurosurgery, and there is no summary of evidence on ERAS applications in cranial neurosurgery.

Methods: The authors systematically reviewed the literature using the PubMed/MEDLINE, Embase, Scopus, and Cochrane Library databases for ERAS protocols and elements. Read More

Photodiagnosis Photodyn Ther 2021 May 4:102322. Epub 2021 May 4.

Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical Collage Hospital, Chinese Academy of Medical Science and Peking Union Medical Collage, 100730, Beijing, China. Electronic address:

Background: Medicinal therapies such as systemic retinoids and antibiotics have shown efficacy in the treatment of dissecting cellulitis of the scalp (DCS), but refractory cases are common. 5-Aminolevulinic acid photodynamic therapy (ALA-PDT) has been successfully used in medicine-resistant cases in recent years.

Methods: 12 patients who received ALA-PDT in addition to formally failed medicinal therapies were interviewed by telephone regarding improvement of symptoms, satisfaction, and side effects. Read More

J Eur Acad Dermatol Venereol 2021 May 7. Epub 2021 May 7.

Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.

Background: Dermoscopy and Reflectance Confocal Microscopy (RCM) features of scalp melanoma according to lesion location and histopathology have not been fully investigated.

Objectives: To reveal dermoscopic and RCM features of scalp melanoma according to lesion location and histopathology.

Methods: We retrospectively retrieved images of suspicious, atypical excised, flat melanocytic lesions of the scalp, assessed on dermoscopy and RCM at five centers, from June 2007 to April 2020. Read More

Mil Med 2021 May 7. Epub 2021 May 7.

Department of Dermatology, Naval Medical Center Portsmouth, Portsmouth, VA 23708, USA.

Scalp avulsion is a rare trauma in the developed world but is a common injury in countries with poorly established infrastructure and safety regulations. This case reports the long-term sequelae of this injury, observed while conducting a humanitarian mission, and discusses immediate actions for management in an acute setting. We aim to increase awareness about this injury, its risk factors, and treatment options to better prepare clinicians in the developed world to provide care for this condition in the austere environment, which may include not only chronic pain, functional, and aesthetic concerns, but also a psychological impact that persists years after the initial injury. Read More

Indian Dermatol Online J 2021 Mar-Apr;12(2):302-306. Epub 2021 Feb 22.

Department of Dermatology, Venereology and Leprosy, Government Medical College, Amritsar, Punjab, India.

Verrucous epidermal nevi (VEN) are cutaneous hamartomas characterized by keratinocytic hyperplasia. Majority are linear in distribution and tend to follow the Blaschko lines; however, some may have zosteriform (segmental) or systematized distribution involving widespread areas of skin. The systematized ones are further classified into "" when one-half of the body is affected, and "" showing bilateral distribution, both being the uncommon forms. Read More

Indian Dermatol Online J 2021 Mar-Apr;12(2):250-257. Epub 2021 Mar 2.

Department of Dermatology, Medical College and Hospital, Kolkata, West Bengal, India.

Background: Childhood alopecia areata (AA) is a common cause of dermatologic consultation; however, data is scarce in the present set-up.

Objectives: To evaluate the clinico-epidemiological profile of childhood AA along with dermoscopic correlation.

Methods: We conducted a cross-sectional study including 50 new cases of childhood AA for 1 year. Read More

Dtsch Med Wochenschr 2021 May 6;146(10):645-646. Epub 2021 May 6.

Universitätshautklinik Leipzig.

Clin Imaging 2021 Apr 29;76:189-194. Epub 2021 Apr 29.

Radiology and Biomedical Imaging, Yale School of Medicine, PO Box 208042, Tompkin's East 2, New Haven, CT 06520-8042, United States.

Background: Errors of detection ("misses") are the major source of error in radiology. There is sparse prior literature describing patterns of detection error on CT head imaging.

Purpose: The objective of this study was to gain insight to areas on CT head imaging where radiologists are most likely to miss clinically relevant findings. Read More

J Cosmet Dermatol 2021 May 6. Epub 2021 May 6.

Department of Dermatology, Municipal Clinics Karlsruhe, Karlsruhe, Germany.

Background: Considerable parts of the global population are affected by androgenetic alopecia (AGA).

Aims: The efficacy of a foam containing nicotinic acid hexyl ester, polyphenols, zinc, glycine, and caffeine in comparison with a vehicle control foam was assessed in a double-blind vehicle-controlled study in men with AGA over 6 months.

Patients/methods: Sixty-two men with AGA were assigned either to the active ingredients (verum) or the vehicle group. Read More

Case Rep Hematol 2021 16;2021:6623706. Epub 2021 Apr 16.

Department of Hematology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 35, Aarhus N 8200, Denmark.

Langerhans cell histiocytosis (LCH) is an infrequent disease, characterized by oligoclonal proliferation of immature myeloid-derived cells. However, the exact pathogenesis remains unknown. In rare cases, LCH is present in patients with concomitant myeloid proliferative neoplasms. Read More

J Indian Assoc Pediatr Surg 2021 Jan-Feb;26(1):60-62. Epub 2021 Jan 11.

Department of Pediatric Surgery, Maulana Azad Medical College, New Delhi, India.

Congenital cutaneous peripheral primitive neuroectodermal tumor (pPNET) is very rare and also very rarely located in scalp. Only two cases of PNET as primary tumor in scalp are reported so far in the literature. Non mutilating surgical excision, combined with chemotherapy and radiotherapy are used in treating these rare tumors. Read More

Neuroscience 2021 May 2. Epub 2021 May 2.

Department of Clinical Neurophysiology, University Medical Center Göttingen, Germany; Department of Neuroanatomy, Institute of Anatomy and Cell Biology, University of Freiburg, Germany. Electronic address:

This study was conducted to provide a better understanding of the role of electric field strength in the production of aftereffects in resting state scalp electroencephalography by repetitive transcranial magnetic stimulation (rTMS) in humans. We conducted two separate experiments in which we applied rTMS over the left parietal-occipital region. Prospective electric field simulation guided the choice of the individual stimulation intensities. Read More

Brain Topogr 2021 May 5. Epub 2021 May 5.

The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.

"Bad channels" are common phenomena during scalp electroencephalography (EEG) recording that arise due to various technique-related reasons, and reconstructing signals from bad channels is an inevitable choice in EEG processing. However, current interpolation methods are all based on purely mathematical interpolation theory, ignoring the neurophysiological basis of the EEG signals, and their performance needs to be further improved, especially when there are many scattered or adjacent bad channels. Therefore, a new interpolation method, named the reference electrode standardization interpolation technique (RESIT), was developed for interpolating scalp EEG channels. Read More

Can J Neurol Sci 2021 May 5:1-4. Epub 2021 May 5.

JAAD Case Rep 2021 May 25;11:90-92. Epub 2021 Mar 25.

Department of Dermatology, Mohammed V University in Rabat, Ibn Sina University Hospital, Rabat, Morocco.

J Neuroeng Rehabil 2021 May 4;18(1):74. Epub 2021 May 4.

Institute of Electric Engineering, Yanshan University, Qinhuangdao, 066004, Hebei, China.

Background: The key challenge to constructing functional corticomuscular coupling (FCMC) is to accurately identify the direction and strength of the information flow between scalp electroencephalography (EEG) and surface electromyography (SEMG). Traditional TE and TDMI methods have difficulty in identifying the information interaction for short time series as they tend to rely on long and stable data, so we propose a time-delayed maximal information coefficient (TDMIC) method. With this method, we aim to investigate the directional specificity of bidirectional total and nonlinear information flow on FCMC, and to explore the neural mechanisms underlying motor dysfunction in stroke patients. Read More