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    Ecological Study of Skin Diseases in Delhi Area.
    Indian J Dermatol Venereol Leprol 1979 Jul-Aug;45(4):260-264
    The present study is a portrayal of the incidence of skin diseases viz. skin problems in a house to house survey of a communityand its comparison with 5 years (1971-1976) statistical analysis of various dermatoses is represented in graphic form. Data collected reflect the prevalence of common skin problems. Read More

    Bacteriological Analysis of Patients Suffering From Infected Scabies.
    Indian J Dermatol Venereol Leprol 1980 Jul-Aug;46(4):223-225
    Scabies is considered to be the commonest disease among the patient attending most Dermatology outpatientdepartments in ourcountry. Pyoderma sometimes appears as the main clinical presentation in scabies. The treatment of pyoderma can be rational only if the clinician has thorough knowledge of the nature and behaviour of the causative organisms as well as their sensitivity patterns to antibiotics. Read More

    Scabies in a bilateral hand allograft recipient: An additional mimicker of acute skin rejection in vascularized composite allotransplantation.
    Transpl Infect Dis 2017 Feb 17. Epub 2017 Feb 17.
    Department of Nephrology, Edouard Herriot Hospital Group, Lyon, France.
    Vascularized composite tissue allografts include skin, which frequently undergoes, in the early post-graft period, acute rejections. The diagnosis of acute rejection may be difficult as it can be mimicked by several dermatoses. We present a bilateral hand allograft recipient who developed, 16. Read More

    Common Skin Conditions in Children: Skin Infections.
    FP Essent 2017 Feb;453:26-32
    University of North Carolina Chapel Hill School of Medicine Dermatology Residency Program, 410 Market St. Suite 400 CB#7715, Chapel Hill, NC 27516.
    Skin infections account for a significant subset of dermatologic conditions of childhood. Common cutaneous viral infections in children include warts, molluscum contagiosum, hand-foot-and-mouth disease, and herpes simplex. Although viral infections are self-limited and often only mildly symptomatic, they can cause anxiety, embarrassment, and health care use. Read More

    A scabies outbreak in a diabetic and collagen disease ward: Management and prevention.
    Exp Ther Med 2016 Dec 27;12(6):3711-3715. Epub 2016 Oct 27.
    Department of General Medicine and Emergency Care, Toho University School of Medicine, Omori Hospital, Ota-ku, Tokyo 143-8541, Japan.
    Scabies is an infection caused by Sarcoptes scabiei. In developed countries, scabies remains an important public health problem in hospitals and care facilities among elderly or immunocompromised patients. There are a number of medical providers who have not experienced scabies and there has been confusion surrounding its management and prevention. Read More

    Norwegian scabies - rare case of atypical manifestation.
    An Bras Dermatol 2016 Nov-Dec;91(6):826-828
    Hospital do Câncer de Cascavel (Uopeccan) - Cascavel (PR), Brazil.
    Human scabies affects all social classes and different races around the world. It is highly contagious, but the exact figures on its prevalence are unknown. A 19-year-old male patient was admitted to the emergency room reporting fever (38°C) and multiple lesions throughout the body, except face, soles, and palms. Read More

    Insight into scabies.
    JAAPA 2017 Feb;30(2):1-3
    At the time this article was written, Faye Mariz Razon was a student in the PA program at LSUHSC School of Allied Health. Emily Weidman-Evans is a clinical associate professor in the PA program at LSUHSC. The authors have disclosed no potential conflicts of interest, financial or otherwise.
    Scabies, an infectious disease caused by the scabies mite, manifests as an intensely pruritic skin rash. Children, the underprivileged, and patients with immunocompromise are at a higher risk of acquiring this contagious disease. Infectivity occurs worldwide in patients of all races, ages, and sex. Read More

    [Scabies of the nail unit in an infant].
    Ann Dermatol Venereol 2017 Jan 4. Epub 2017 Jan 4.
    Université François-Rabelais de Tours, 37000 Tours, France; Service de dermatologie, unité de dermatologie pédiatrique, CHRU de Tours, 37044 Tours cedex 9, France.
    Background: There are no guidelines regarding the management of scabies in infants and recurrence is common at this age. We report the case of an infant with subungual hyperkeratosis and ungual lesions subsequent to classic scabies.

    Patients And Methods: A 7-month-girl, treated 6 weeks earlier with esdepallethrin for scabies, consulted for acquired lesions on 3 toe nails. Read More

    Epidemiology, Diagnosis, and Treatment of Scabies in a Dermatology Office.
    J Am Board Fam Med 2017 1/2;30(1):78-84
    From the Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC.
    Background: Scabies is a neglected skin disease, and little is known about current incidence and treatment patterns in the United States. The purpose of this study was to examine demographic data, treatment types, success of treatment, and misdiagnosis rate of scabies in an outpatient dermatology clinic.

    Methods: A retrospective chart review of patients diagnosed with scabies within the past 5 years was performed. Read More

    A new treatment regimen with permethrin in scabies.
    G Ital Dermatol Venereol 2016 Dec 16. Epub 2016 Dec 16.
    Postgraduate School of Dermatology and Venereology, University of Milan, Milan, Italy.
    Background: Topical permethrin, applied once daily, is considered as the most effective treatment in scabies.

    Methods: Eighty-nine adult immunocompetent patients with scabies were treated with 5% permethrin cream: 42 patients were treated with a single application/day (group I); 47 patients were treated with one application/day for two consecutive days (group II). Clinical diagnosis of scabies was confirmed by microscopical examinations. Read More

    Emergence of Novel Pathogenic Streptomyces Species by Site-Specific Accretion and cis-Mobilization of Pathogenicity Islands.
    Mol Plant Microbe Interact 2017 Jan 30;30(1):72-82. Epub 2017 Jan 30.
    Department of Plant Pathology, University of Florida, Gainesville, U.S.A.
    The main pathogenicity factor of Streptomyces species associated with the potato common scab disease is a nitrated diketopiperazine called thaxtomin A (ThxA). In Streptomyces scabiei (syn. S. Read More

    The Treatment of Scabies.
    Dtsch Arztebl Int 2016 Nov;113(45):757-762
    Division of Evidence-Based Medicine (dEBM), Department of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin; Department of Dermatology and Venereology, University Hospital Halle.
    Background: Scabies is a contagious infestation transmitted by skin-to-skin contact and sometimes by contact with contaminated material. The scabies mite burrows into the skin, producing a papular rash and severe itch at typical sites of predilection.

    Methods: We systematically reviewed the literature to compare the efficacy of various anti-scabies agents, including a calculation of relative risks and confidence intervals. Read More

    Pet-Related Infections.
    Am Fam Physician 2016 Nov;94(10):794-802
    School of Veterinary Sciences, University of Bristol, Langford, United Kingdom.
    Physicians and veterinarians have many opportunities to partner in promoting the well-being of people and their pets, especially by addressing zoonotic diseases that may be transmitted between a pet and a human family member. Common cutaneous pet-acquired zoonoses are dermatophytosis (ringworm) and sarcoptic mange (scabies), which are both readily treated. Toxoplasmosis can be acquired from exposure to cat feces, but appropriate hygienic measures can minimize the risk to pregnant women. Read More

    The effects of climate factors on scabies. A 14-year population-based study in Taiwan.
    Parasite 2016 1;23:54. Epub 2016 Dec 1.
    Graduate Institute of Life Sciences, National Defense Medical Center, 114 Tapei, Taiwan - Department of Pathology and Graduate Institute of Pathology and Parasitology, the Tri-Service General Hospital, National Defense Medical Center, 114 Tapei, Taiwan - Biobank Management Center of the Tri-Service General Hospital, National Defense Medical Center, 114 Tapei, Taiwan.
    Scabies is a common infectious disease and can cause severe outbreaks if not controlled quickly. Besides personal contact history, environmental factors are also important. This study analyzed the effects of environmental climate factors on the incidence of scabies in Taiwan. Read More

    Safety of Topical Medications for Scabies and Lice in Pregnancy.
    Indian J Dermatol 2016 Nov-Dec;61(6):583-587
    Dermatology and Pathology, Rutgers New Jersey Medical School and the Rutgers University School of Public Affairs and Administration Newark, New Jersey, USA.
    Medications should be employed with caution in women of childbearing age. Topical medications have little systemic absorption. Therefore, they are considered safer than oral or parenteral agents and less likely to be embryotoxic or fetotoxic. Read More

    A Study of Clinical Profile and Quality of Life in Patients with Scabies at a Rural Tertiary Care Centre.
    J Clin Diagn Res 2016 Oct 1;10(10):WC01-WC05. Epub 2016 Oct 1.
    Resident, Department of Dermatology and Venereology, Pramukhswami Medical College , Karamsad, Gujarat, India .
    Introduction: Scabies is a contagious disease primarily related to poverty and overcrowding, it rapidly spreads from person to person specially in people with poor hygiene. We come across many patients from rural areas with scabies. In India the incidence ranges from 13% to 59% in rural and urban areas. Read More

    S1 guidelines on the diagnosis and treatment of scabies - short version.
    J Dtsch Dermatol Ges 2016 Nov;14(11):1155-1167
    Department of Dermatology, Venereology and Allergology, University Hospital Würzburg.
    The goals of this German guideline are the improvement of diagnosis and therapy of scabies, the implementation of a coordinated action in outbreaks of scabies, and the control of this infestation in large migration or refugee flows.Sarcoptes scabiei var. hominis is transmitted by direct skin-to-skin contact of sufficient duration. Read More

    A clinical study of cutaneous changes in pregnancy.
    J Epidemiol Glob Health 2017 Mar 19;7(1):63-70. Epub 2016 Nov 19.
    Department of Dermatology, Government Medical College, Alappuzha, Kerala, India.
    Background/objective: Pregnant women experience a myriad of physiological and metabolic changes that affect different organ systems in the body. Cutaneous and appendageal alterations that manifest during pregnancy are largely modulated by hormonal, immunologic, and metabolic factors. Detailed reports encompassing physiological changes and specific dermatoses of pregnancy and effects of various dermatoses on pregnant women are scanty in literature. Read More

    Community seroprevalence survey for yaws and trachoma in the Western Division of Fiji.
    Trans R Soc Trop Med Hyg 2016 Dec 16;110(10):582-587. Epub 2016 Nov 16.
    Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Background: Both yaws and trachoma are endemic in several countries in the Pacific. In co-endemic countries there may be potential synergies between both control programmes.

    Methods: We undertook a cluster randomised trachoma and yaws seroprevalence survey of children in the Western Division of Fiji. Read More

    Molecular characterization of calmodulin from Sarcoptes scabiei.
    Parasitol Int 2017 Apr 10;66(2):1-6. Epub 2016 Nov 10.
    Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, China. Electronic address:
    Scabies, caused by the mite Sarcoptes scabiei, is a highly contagious parasitic disease that affects millions of people and other mammals worldwide. Calmodulin (CaM) is an important calcium sensor that participates in various critical physiological processes. In this study, the CaM of Sarcoptes scabiei (SsCaM) was cloned and expressed, and sequence analyses were performed using bioinformatics tools. Read More

    [Scabies in childhood and adolescence].
    Hautarzt 2016 Dec;67(12):1007-1020
    Abteilung für translationale Dermatoinfektiologie, Westfälische Wilhelms-Universität, Münster, Deutschland.
    Scabies is a common parasitosis, occurring worldwide and at any age that impairs the quality of life of patients and their families by the itching and the stigmatization. The main aims of therapy are destroying the mites Sarcoptes scabiei var. hominis that infect the stratum corneum and reduction of the itching. Read More

    Opportunities for Integrated Control of Neglected Tropical Diseases That Affect the Skin.
    Trends Parasitol 2016 Nov 13;32(11):843-854. Epub 2016 Sep 13.
    Centre for International Child Health, University of Melbourne, Melbourne, Australia; Group A Streptococcal Research, Murdoch Childrens Research Institute, Melbourne, Australia.
    Many neglected tropical diseases (NTDs) affect the skin, causing considerable disability, stigma, and exacerbation of poverty. However, there has been relatively little investment into laboratory research, epidemiology, diagnostic tools or management strategies to control tropical skin disease. Integration may advance the control of skin disease across a range of domains, including mapping, diagnosis, clinical management, and community control measures such as mass drug administration. Read More

    Enzymatic hydrolysis by transition-metal-dependent nucleophilic aromatic substitution.
    Nat Chem Biol 2016 Dec 3;12(12):1031-1036. Epub 2016 Oct 3.
    School of Chemistry &Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, USA.
    Nitroaromatic compounds are typically toxic and resistant to degradation. Bradyrhizobium species strain JS329 metabolizes 5-nitroanthranilic acid (5NAA), which is a molecule secreted by Streptomyces scabies, the plant pathogen responsible for potato scab. The first biodegradation enzyme is 5NAA-aminohydrolase (5NAA-A), a metalloprotease family member that converts 5NAA to 5-nitrosalicylic acid. Read More

    Protective effects of Solanum cernuum extract against chromosomal and genomic damage induced by methyl methanesulfonate in Swiss mice.
    Biomed Pharmacother 2016 Oct 20;83:1111-1115. Epub 2016 Aug 20.
    University of Franca, Avenida Dr. Armando Salles de Oliveira, 201-Parque Universitário, 14404-600, Franca, São Paulo, Brazil. Electronic address:
    Solanum cernuum Vell is a Brazilian shrub or small tree, restricted to Southeast states of the country. The leaves are commercialized as "panacéia" and indicated for the treatment of urinary disorders, gonorrhea, scabies, skin diseases and as desobstruent, diuretic and antiarrhythmic. The hydroalcholic extract is active in the treatment of gastric ulcer. Read More

    Evaluation of three enzyme-linked immunosorbent assays for sarcoptic mange diagnosis and assessment in the Iberian ibex, Capra pyrenaica.
    Parasit Vectors 2016 Oct 21;9(1):558. Epub 2016 Oct 21.
    Servei d'Ecopatologia de Fauna Salvatge (SEFaS), Wildlife Health Service - Departament de Medicina i Cirurgia Animal, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, E-08193, Spain.
    Background: Sarcoptic mange is a contagious skin disease caused by the mite Sarcoptes scabiei, affecting different mammalian species worldwide including the Iberian ibex (Capra pyrenaica), in which mortalities over 90 % of the population have been reported. No efficient diagnostic methods are available for this disease, particularly when there are low mite numbers and mild or no clinical signs. In this study, three enzyme-linked immunosorbent assays (ELISA) developed for dog (ELISA A), Cantabrian chamois (Rupicapra pyrenaica parva) (ELISA B) and Alpine chamois (Rupicapra rupicapra) (ELISA C), were evaluated to detect specific antibodies (IgG) to sarcoptic mange in Iberian ibex sera. Read More

    [Waves of refugees represent challenge for European dermatologists].
    Hautarzt 2016 Dec;67(12):1021-1024
    Abteilung für Dermatologie und Venerologie, Landeskrankenhaus Feldkirch, Akademisches Lehrkrankenhaus, Carinagasse 47, 6800, Feldkirch, Österreich.
    With the increasing number of asylum seekers in recent months, European dermatologists have been confronted with rising numbers of patients with formerly rare skin diseases and unusual infectious skin diseases that were previously scarcely observed at our latitude. Thorough examination of the patients medical history, including the routes of travel and the country of origin of the patients, detailed clinical and laboratory examinations, and - if necessary - referral to a special treatment center allow rapid and targeted treatment. Read More

    Intralymphatic CD30+ T-cell proliferation during DRESS: a mimic of intravascular lymphoma.
    J Cutan Pathol 2016 Nov 22;43(11):1036-1040. Epub 2016 Aug 22.
    Department of Dermatology, Strasbourg University Hospital, Strasbourg, France.
    Introduction: We describe the case of a patient presenting with drug rash with eosinophilia and systemic symptoms (DRESS), where cutaneous biopsy revealed intravascular atypical lymphocytes suggestive of lymphoma.

    Case Report: A 77-year-old man was treated with antibiotics for a hip prosthesis infection. Eight weeks later, he developed a maculo-papulous eruption, edema of the extremities, fever and blood eosinophilia. Read More

    Pharmacokinetics of ivermectin applied topically by whole-body bathing method in healthy volunteers.
    J Dermatol 2016 Oct 15. Epub 2016 Oct 15.
    Department of Medical Safety, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, Japan.
    As a novel administration method of ivermectin (IVM) for scabies treatment, we proposed a "whole-body bathing method (WBBM)". In this method, the patients would bathe themselves in a bathing fluid containing IVM at an effective concentration. Previously, we demonstrated that WBBM could deliver IVM to the skin but not to the plasma in rats. Read More

    The management of scabies outbreaks in residential care facilities for the elderly in England: a review of current health protection guidelines.
    Epidemiol Infect 2016 Nov;144(15):3121-3130
    Surrey and Sussex Health Protection Team (Public Health England South East Centre),Horsham,UK.
    Commonly thought of as a disease of poverty and overcrowding in resource-poor settings globally, scabies is also an important public health issue in residential care facilities for the elderly (RCFE) in high-income countries such as the UK. We compared and contrasted current local Health Protection Team (HPT) guidelines for the management of scabies outbreaks in RCFE throughout England. We performed content analysis on 20 guidelines, and used this to create a quantitative report of their variation in key dimensions. Read More

    Preclinical Study of Single-Dose Moxidectin, a New Oral Treatment for Scabies: Efficacy, Safety, and Pharmacokinetics Compared to Two-Dose Ivermectin in a Porcine Model.
    PLoS Negl Trop Dis 2016 Oct 12;10(10):e0005030. Epub 2016 Oct 12.
    APHP, Hôpital Henri-Mondor, Department of Dermatology, UPEC, Créteil, France.
    Background: Scabies is one of the commonest dermatological conditions globally; however it is a largely underexplored and truly neglected infectious disease. Foremost, improvement in the management of this public health burden is imperative. Current treatments with topical agents and/or oral ivermectin (IVM) are insufficient and drug resistance is emerging. Read More

    Report - Most common body parts infected with scabies in children and its control.
    Pak J Pharm Sci 2016 Sep;29(5):1715-1717
    Institute of Environmental Studies, University of Karachi, Karachi, Pakistan.
    Scabies a skin disease caused by mite Sarcoptes scabiei is common in Pakistan and spreads mostly where there is frequent skin to skin contact. In the present study children belonging to four age groups 0-3 years, 4-6 years, 7-9 years and 10-12 years attending Baqai Institute and Hospital Gadap from June-September 2013 were examined. The association between scabies of different human parts and age for boys was significant (p<0. Read More

    Parasites.
    Microbiol Spectr 2016 Aug;4(4)
    Parasites are an important cause of human disease worldwide. The clinical severity and outcome of parasitic disease is often dependent on the immune status of the host. Specific parasitic diseases discussed in this chapter are amebiasis, giardiasis, cryptosporidiosis, cyclosporiasis, cystoisosporiasis, microsporidosis, granulomatous amebic encephalitis, toxoplasmosis, leishmaniasis, Chagas disease, malaria, babesiosis, strongyloidiasis, and scabies. Read More

    Evaluation of pharmacokinetics and efficacy of ivermectin following oral administration in dogs against experimental infection of Ctenocephalides felis felis and Rhipicephalus sanguineus.
    Vet Parasitol 2016 Sep 11;228:167-171. Epub 2016 Sep 11.
    Animal Parasitology Department, Federal Rural University of Rio de Janeiro (UFRRJ), BR 465, Km. 7, 23897-000 Seropédica, RJ, Brazil.
    With the increasing number of pets in home the human-animal relationship is increasingly close and care about control disease growing. Ivermectin (IVM) is frequently used because its proven safety. IVM is recommended for the treatment of demodectic scabies and prevention of heartworm in dogs, but informally is extremely used to control of Ctenocephalides felis felis and Rhipicephalus sanguineus. Read More

    Indicators of health and safety among institutionalized older adults.
    Rev Esc Enferm USP 2016 Jul-Aug;50(4):602-609
    Universidade Estadual do Ceará, Departamento de Enfermagem, Fortaleza, Ceará, Brazil.
    Objective: To identify the incidence of mortality, diarrheal diseases, scabies and falls; and the prevalence of pressure ulcers - all of which are related to the safety ofinstitutionalized older adults.

    Method: This was a documentary retrospective study developed in a long-term residential careinstitution for older adults in the Northeast region of Brazil. The data were gathered from records of health assessment indicators filed between January 2008 and December 2015. Read More

    Scabies increased the risk and severity of COPD: a nationwide population-based study.
    Int J Chron Obstruct Pulmon Dis 2016;11:2171-2178. Epub 2016 Sep 9.
    Graduate Institute of Life Sciences, National Defense Medical Center; Department of Pathology, Graduate Institute of Pathology and Parasitology, Tri-Service General Hospital, National Defense Medical Center; Biobank Management Center, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
    Background: Scabies is a common parasitic infectious disease, and COPD is a major pulmonary disease. However, there have been no previous studies that have investigated the relationship between scabies and COPD.

    Materials And Methods: This nationwide population-based study included a total of 3,568 patients with scabies as the study group and 14,255 patients as a control group. Read More

    Protocol for the systematic review of the prevention, treatment and public health management of impetigo, scabies and fungal skin infections in resource-limited settings.
    Syst Rev 2016 Sep 23;5(1):162. Epub 2016 Sep 23.
    Telethon Kids Institute, University of Western Australia, West Perth, Australia.
    Background: Impetigo, scabies, and fungal skin infections disproportionately affect populations in resource-limited settings. Evidence for standard treatment of skin infections predominantly stem from hospital-based studies in high-income countries. The evidence for treatment in resource-limited settings is less clear, as studies in these populations may lack randomisation and control groups for cultural, ethical or economic reasons. Read More

    Nail Scabies: An Unusual Presentation Often Overlooked and Mistreated.
    J Trop Pediatr 2016 Sep 9. Epub 2016 Sep 9.
    Division of Pediatric Dermatology, Department of Pediatrics Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
    Nail scabies is an interesting clinical presentation of scabies. Although it is usually found concomitant with characteristic dermatologic manifestations, it may present as an isolated finding in the immunocompromised host. This condition is commonly mistaken with other diseases such as nail dystrophy, nail psoriasis and onychomycosis. Read More

    Dermoscopy in General Dermatology: A Practical Overview.
    Dermatol Ther (Heidelb) 2016 Dec 9;6(4):471-507. Epub 2016 Sep 9.
    Department of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Udine, Italy.
    Over the last few years, dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders. In this article, we sought to provide an up-to-date practical overview on the use of dermoscopy in general dermatology by analysing the dermoscopic differential diagnosis of relatively common dermatological disorders grouped according to their clinical presentation, i.e. Read More

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