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    Treatment of Scabies and Pediculosis in Health Education Publications and Folk Medicine of Eastern Croatia - Slavonija, Baranja, and Western Srijem County.
    Acta Dermatovenerol Croat 2018 Apr;26(1):33-38
    Ivanka Muršić, MD, University Hospital Centre Osijek, Department of Dermatology and Venereology J. Huttlera 4, 31000 Osijek, Croatia;
    Scabies and pediculosis are common parasitic infestations of the skin and hair, manifesting with intense pruritus and effectively treated with modern medications. Because of the attached social stigma linking it with poverty and poor hygiene, patients will often attempt alternative folk-based remedies before confiding in their physicians. We conducted a comprehensive bibliographical study of historic folk literature and interviewed 70 individuals experienced in everyday application of folk medicine in order to categorize available remedies and provide a modern, scientific comment on their effectiveness and dangers. Read More

    The Epidemiology of Scabies and Pediculosis in Kayseri.
    Turkiye Parazitol Derg 2018 May 21. Epub 2018 May 21.
    Halk Sağlığı Müdürlüğü, Bulaşıcı Hastalık Kontrol Programları Şubesi, Kayseri, Türkiye.
    Objective: The present study aimed to evaluate scabies and pediculosis cases in the city of Kayseri and to contribute to the epidemiological data in Turkey.

    Methods: Data for the present study were obtained from the Kayseri Directorate of Public Health. The distribution of lice and scabies according to age, sex, and years was evaluated retrospectively. Read More

    Skin disease prevalence study in schoolchildren in rural Côte d'Ivoire: Implications for integration of neglected skin diseases (skin NTDs).
    PLoS Negl Trop Dis 2018 May 17;12(5):e0006489. Epub 2018 May 17.
    Global Buruli Ulcer Initiative, World Health Organization, Geneva, Switzerland.
    Background: Early detection of several skin-related neglected tropical diseases (skin NTDs)-including leprosy, Buruli ulcer, yaws, and scabies- may be achieved through school surveys, but such an approach has seldom been tested systematically on a large scale in endemic countries. Additionally, a better understanding of the spectrum of skin diseases and the at-risk populations to be encountered during such surveys is necessary to facilitate the process.

    Methods: We performed a school skin survey for selected NTDs and the spectrum of skin diseases, among primary schoolchildren aged 5 to 15 in Côte d'Ivoire, West Africa. Read More

    Efficacy of ivermectin mass-drug administration to control scabies in asylum seekers in the Netherlands: A retrospective cohort study between January 2014 - March 2016.
    PLoS Negl Trop Dis 2018 May 17;12(5):e0006401. Epub 2018 May 17.
    University of Groningen, Department of Internal Medicine, Infectious Disease Unit, University Medical Centre Groningen, Groningen, The Netherlands.
    Scabies is a skin infestation with the mite Sarcoptes scabiei causing itch and rash and is a major risk factor for bacterial skin infections and severe complications. Here, we evaluated the treatment outcome of 2866 asylum seekers who received (preventive) scabies treatment before and during a scabies intervention programme (SIP) in the main reception centre in the Netherlands between January 2014 and March 2016. A SIP was introduced in the main national reception centre based on frequent observations of scabies and its complications amongst Eritrean and Ethiopian asylum seekers in the Netherlands. Read More

    Phylogenetic relationships, stage-specific expression and localisation of a unique family of inactive cysteine proteases in Sarcoptes scabiei.
    Parasit Vectors 2018 May 16;11(1):301. Epub 2018 May 16.
    QIMR Berghofer Medical Research Institute, Infectious Diseases Program, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.
    Background: Scabies is worldwide one of the most common, yet neglected, parasitic skin infections, affecting a wide range of mammals including humans. Limited treatment options and evidence of emerging mite resistance against the currently used drugs drive our research to explore new therapeutic candidates. Previously, we discovered a multicopy family of genes encoding cysteine proteases with their catalytic sites inactivated by mutation (SMIPP-Cs). Read More

    A cross-sectional investigation of the health needs of asylum seekers in a refugee clinic in Germany.
    BMC Fam Pract 2018 May 16;19(1):64. Epub 2018 May 16.
    General Medicine Division, MK3, Technical University Dresden, Carus School of Medicine, Fetscherstrasse 74, 01307, Dresden, Germany.
    Background: Over one million asylum seekers were registered in Germany in 2016, most from Syria and Afghanistan. The Refugee Convention guarantees access to healthcare, however delivery mechanisms remain heterogeneous. There is an urgent need for more data describing the health conditions of asylum seekers to guide best practices for healthcare delivery. Read More

    Calculation of the age of the first infection for skin sores and scabies in five remote communities in northern Australia.
    Epidemiol Infect 2018 May 8:1-8. Epub 2018 May 8.
    Murdoch Children's Research Institute,The Royal Children's Hospital,Melbourne,Victoria,Australia.
    Prevalence of skin sores and scabies in remote Australian Aboriginal communities remains unacceptably high, with Group A Streptococcus (GAS) the dominant pathogen. We aim to better understand the drivers of GAS transmission using mathematical models. To estimate the force of infection, we quantified the age of first skin sores and scabies infection by pooling historical data from three studies conducted across five remote Aboriginal communities for children born between 2001 and 2005. Read More

    Atypical crusted scabies in a patient with chronic liver disease caused by hepatitis B and D viruses.
    An Bras Dermatol 2018 Mar;93(2):277-278
    Fundação Alfredo da Matta, Manaus, AM, Brazil.
    Crusted scabies is a less common variant of scabies that is highly contagious, difficult to treat and involves infestation by Sarcoptes scabiei var. hominis. The classical clinical presentation includes crusted, scaly and generally non-pruritic lesions usually located on the head, neck, palmar, plantar and periungual region. Read More

    Infectious disease profiles of Syrian and Eritrean migrants presenting in Europe: A systematic review.
    Travel Med Infect Dis 2018 Apr 24. Epub 2018 Apr 24.
    University of Zurich Centre for Travel Medicine, WHO Collaborating for Travellers' Health, Department of Public Health, Institute for Epidemiology, Biostatistics and Prevention, Hirschengraben 84, 8001 Zurich, Switzerland. Electronic address:
    Background: In the past decade, a large influx of migrants presented in Europe. Their country of origin was mainly either Syria or Eritrea. Public health institutions in host countries in Europe are challenged to screen and care for migrant populations with regard to infectious diseases. Read More

    Biological control of potato common scab by Bacillus amyloliquefaciens Ba01.
    PLoS One 2018 26;13(4):e0196520. Epub 2018 Apr 26.
    Department of Plant Pathology and Microbiology, National Taiwan University, Taipei, Taiwan.
    Potato common scab, which is caused by soil-borne Streptomyces species, is a severe plant disease that results in a significant reduction in the economic value of potatoes worldwide. Due to the lack of efficacious pesticides, crop rotations, and resistant potato cultivars against the disease, we investigated whether biological control can serve as an alternative approach. In this study, multiple Bacillus species were isolated from healthy potato tubers, and Bacillus amyloliquefaciens Ba01 was chosen for further analyses based on its potency against the potato common scab pathogen Streptomyces scabies. Read More

    ITRAQ-based quantitative proteomic analysis of processed L. for reducing the intestinal toxicity.
    Proteome Sci 2018 17;16. Epub 2018 Apr 17.
    1College of Traditional Chinese Pharmacy, Beijing University of Chinese Medicine, North Third Ring Road, Number 11, Chaoyang District, Beijing, 100029 People's Republic of China.
    Background: L., a Traditional Chinese medicine (TCM), is commonly used for the treatment of hydropsy, ascites, constipation, amenorrhea, and scabies. Semen Euphorbiae Pulveratum, which is another type of that is commonly used in TCM practice and is obtained by removing the oil from the seed that is called paozhi, has been known to ease diarrhea. Read More

    Delusional infestation in psychodermatology.
    G Ital Dermatol Venereol 2018 Aug 18;153(4):497-505. Epub 2018 Apr 18.
    Department of Dermatology, The University of Texas at Austin Dell Medical School, Austin, TX, USA -
    Delusional infestation (DI), also known as delusional parasitosis, consists of a patient's strong belief that he or she is infested with a nonliving substance or living organism despite lack of medical evidence to support this belief. The most commonly reported sources of infestation include insects, fibrous strands, worms, and scabies. DI is predominantly seen in women and older patients. Read More

    Identification of a novel aminopolycarboxylic acid siderophore gene cluster encoding the biosynthesis of ethylenediaminesuccinic acid hydroxyarginine (EDHA).
    Metallomics 2018 May;10(5):722-734
    Interfaculty Institute of Microbiology and Infection Medicine Tuebingen, Microbiology/Biotechnology, University of Tuebingen, Tuebingen, Germany.
    The mechanism of siderophore-mediated iron supply enhances fitness and survivability of microorganisms under iron limited growth conditions. One class of naturally occurring ionophores is the small aminopolycarboxylic acids (APCAs). Although they are structurally related to the most famous anthropogenic chelating agent, ethylenediaminetetraacetate (EDTA), they have been largely neglected by the scientific community. Read More

    Tackling scabies: novel agents for a neglected disease.
    Int J Dermatol 2018 Apr 16. Epub 2018 Apr 16.
    Department of Dermatology, Venereology and Leprosy, Sri Manakula Vinayagar Medical College and Hospital, Pondicherry, Pondicherry University, Pondicherry, India.
    The scabies mite, Sarcoptes scabiei var hominis, is an obligate ectoparasite of humans. It has been a source of distress for humanity since antiquity. The troublesome mite is emerging triumphant over current acaricidal agents with reports of emerging resistance and treatment failures. Read More

    Early infectious exposures are not associated with increased risk of pediatric-onset multiple sclerosis.
    Mult Scler Relat Disord 2018 Mar 26;22:103-107. Epub 2018 Mar 26.
    Pediatric Multiple Sclerosis Center, University of California San Francisco, San Francisco, CA, USA.
    Objective: We sought to determine if early infectious exposures such as daycare, early use of antibiotics, vaccinations and other germ exposures including pacifier use and playing on grass are associated with multiple sclerosis (MS) risk in children.

    Methods: This was a case-control study of children with MS or clinically isolated syndrome (CIS) and healthy controls enrolled at sixteen clinics participating in the US Network of Pediatric MS Centers. Parents completed a comprehensive environmental questionnaire that captured early infectious exposures, habits, and illnesses in the first five years of life. Read More

    Sex differences in child and adolescent physical morbidity: cohort study.
    BMJ Paediatr Open 2017 29;1(1):e000191. Epub 2017 Dec 29.
    MRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, UK.
    Background: Evidence on sex differences in physical morbidity in childhood and adolescence is based largely on studies employing single/few physical morbidity measures and different informants. We describe sex differences in a wide range of parent/carer-reported physical morbidity measures between ages 4 and 13 years to determine evidence for a generalised pattern of an emerging/increasing female 'excess'.

    Methods: Parents/carers (approximately 90% mothers) of the population-based UK ALSPAC cohort provided data on general health, physical conditions/symptoms and infections in their child approximately annually between ages 4 and 13. Read More

    Observations of Pediatric Disease Prevalence from Pacific Partnership 2015.
    Mil Med 2018 Mar;183(suppl_1):530-537
    Naval Hospital Bremerton, 1 Boone Rd, Bremerton, WA 98312.
    Pacific Partnership is an ongoing yearly humanitarian assistance mission to Pacific Rim countries. Although many case reports and surgical successes have been documented, few data have been published specifically about the primary care mission. This article analyzes outpatient pediatric data collected during Pacific Partnership 2015. Read More

    The efficacy of a nested PCR in detecting cytochrome c oxidase subunit 1 gene of Sarcoptes scabiei var. Hominis for diagnosing scabies.
    Br J Dermatol 2018 Apr 6. Epub 2018 Apr 6.
    Department of Dermatology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
    Background: A widespread scabies infestation, associated to long-term residence in nursing homes, is becoming a serious issue in developed countries. Mineral oil examination is regarded as the gold standard in diagnosing scabies, but the sensitivity of this method is generally low-approximately 50%. Molecular tests may contribute to enhance the sensitivity of current tests for laboratory diagnosis of human scabies. Read More

    CONCOMITANT SEXUALLY TRANSMITTED DISEASES IN PATIENTS WITH DIAGNOSED HIV/AIDS: A RETROSPECTIVE STUDY.
    Afr J Infect Dis 2018 7;12(1 Suppl):83-89. Epub 2018 Mar 7.
    Department of Internal Medicine, Faculty of Medicine-Institute of Tropical Disease-Universitas Airlangga Hospital, Universitas Airlangga, Surabaya 60286, Indonesia.
    Background: Human immunodeficiency virus (HIV) is a virus that causes Acquired Immunodeficiency Syndrome (AIDS) which weaken the human immune system and thus increasing the incidence of sexually transmitted infections (STIs) and vice versa.

    Materials And Methods: A retrospective study of STIs in HIV/AIDS patients in (UPIPI) Dr. Soetomo General Hospital Surabaya was conducted from January 1 2013 to December 31 2014. Read More

    Prevalence of skin diseases amongst Moroccan fishermen.
    Int Marit Health 2018 ;69(1):22-27
    Graduate School of Health Engineering, 24 rue Lafontaine, Quartier Racine, 20100 Casablanca, Morocco.
    Background: The main objective was to evaluate the prevalence of skin diseases amongst fishermen, to specify the different clinical forms, associations and most frequent localisations, and to identify potential aetiological factors. The secondary objectives were to assess the knowledge, attitudes and practices of seafarers regarding occupational dermatoses to conduct information, awareness and education campaigns on risk factors and behaviours and to propose adapted prevention.

    Materials And Methods: This cross-sectional survey involved 1102 artisanal fishermen who attended the annual legal medical consultation at the occupational health service. Read More

    Ivermectin and permethrin for treating scabies.
    Cochrane Database Syst Rev 2018 04 2;4:CD012994. Epub 2018 Apr 2.
    Division of Evidence Based Medicine, Department of Dermatology, Venerology and Allergology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, Berlin, Berlin, Germany, 10117.
    Background: Scabies is an intensely itchy parasitic infection of the skin. It occurs worldwide, but is particularly problematic in areas of poor sanitation, overcrowding, and social disruption. In recent years, permethrin and ivermectin have become the most relevant treatment options for scabies. Read More

    De novo Biosynthesis of "Non-Natural" Thaxtomin Phytotoxins.
    Angew Chem Int Ed Engl 2018 Mar 30. Epub 2018 Mar 30.
    School of Chemistry, Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK.
    Thaxtomins are diketopiperazine phytotoxins produced by Streptomyces scabies and other actinobacterial plant pathogens that inhibit cellulose biosynthesis in plants. Due to their potent bioactivity and novel mode of action there has been considerable interest in developing thaxtomins as herbicides for crop protection. To address the need for more stable derivatives, we have developed a new approach for structural diversification of thaxtomins. Read More

    IgE and T-cell responses to house dust mite allergen components.
    Mol Immunol 2018 Mar 27. Epub 2018 Mar 27.
    Telethon Kids Institute, University of Western Australia, 100 Roberts Rd., Subiaco 6008, Western Australia, Australia. Electronic address:
    Using the terminology for Dermatophagoides pteronyssinus, IgE responses to house dust mites have been shown to be mostly directed to the serodominant Der p 1, 2 and 23 allergen components with mid -tier responses to Der p 4, 5, 7 and 21 that are made by 30-50% of subjects with titers proportional to those of the serodominant specificities. This pattern can be seen to evolve in childhood and although responses to minor allergens appear to contribute little to the total IgE they are at least markers for a greater propensity to develop disease. While Der p 23 is a component that induces prevalent IgE responses, sometimes in the absence of responses to Der p 1and 2, not all studies have found high titers so further investigation is needed. Read More

    Scabies in residential care homes: Modelling, inference and interventions for well-connected population sub-units.
    PLoS Comput Biol 2018 Mar 26;14(3):e1006046. Epub 2018 Mar 26.
    School of Mathematics, University of Manchester, United Kingdom.
    In the context of an ageing population, understanding the transmission of infectious diseases such as scabies through well-connected sub-units of the population, such as residential care homes, is particularly important for the design of efficient interventions to mitigate against the effects of those diseases. Here, we present a modelling methodology based on the efficient solution of a large-scale system of linear differential equations that allows statistical calibration of individual-based random models to real data on scabies in residential care homes. In particular, we review and benchmark different numerical methods for the integration of the differential equation system, and then select the most appropriate of these methods to perform inference using Markov chain Monte Carlo. Read More

    Prevalence of Nail Scabies: A French Prospective Multicenter Study.
    J Pediatr 2018 Mar 23. Epub 2018 Mar 23.
    University François Rabelais Tours, Faculty of Medicine, Tours, France; Department of Dermatology, Unit of Paediatric Dermatology, Centre Hospitalier Régional et Universitaire Tours, Tours, France. Electronic address:
    Introduction: To assess the prevalence of nail involvement in children <16 years old with a confirmed diagnosis of scabies.

    Study Design: Observational, prospective study in 7 French dermatology departments between June 2015 and January 2017. Children were included if they had scabies confirmed by dermoscopy and/or microscopy and if nails could be sampled. Read More

    Cutaneous infections in the mature patient.
    Clin Dermatol 2018 Mar - Apr;36(2):188-196. Epub 2017 Oct 3.
    Sector of Dermatology and Post-Graduation Course in Dermatology, University Hospital and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address:
    Dermatologists must be familiar with the peculiarities of the micro-organisms that may affect the elderly, in order to optimize the diagnosis and treatment of infections, which may affect their skin, especially because the world population is rapidly aging. It is estimated that there will be 434 million individuals over 80 years of age in 2050. Since the elderly population is rapidly increasing and their infections are usually more severe and different from those observed in younger adults, it leads to a statistical increase of the rates regarding hospitalization and mortality caused by infectious diseases among people over 85 years. Read More

    Dynamics of Scabin toxin. A proposal for the binding mode of the DNA substrate.
    PLoS One 2018 15;13(3):e0194425. Epub 2018 Mar 15.
    Department of Molecular and Cell Biology, University of Guelph, Guelph, Ontario, Canada.
    Scabin is a mono-ADP-ribosyltransferase enzyme and is a putative virulence factor produced by the plant pathogen, Streptomyces scabies. Previously, crystal structures of Scabin were solved in the presence and absence of substrate analogues and inhibitors. Herein, experimental (hydrogen-deuterium exchange), simulated (molecular dynamics), and theoretical (Gaussian Network Modeling) approaches were systematically applied to study the dynamics of apo-Scabin in the context of a Scabin·NAD+·DNA model. Read More

    Sarcoptes infestation in two miniature pigs with zoonotic transmission - a case report.
    BMC Vet Res 2018 Mar 13;14(1):91. Epub 2018 Mar 13.
    Division of Clinical Dermatology, Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern, Bern, Länggassstrasse 128, 3012, Berne, CH, Switzerland.
    Background: Scabies is a contagious skin disease rarely described in miniature pigs. To the best of the authors' knowledge, a zoonotic transfer from infected pet pigs to humans has not been reported previously.

    Case Presentation: This case report describes the infestation with Sarcoptes scabiei mites in two miniature pigs presenting with unusual clinical signs, and disease transmission to a child. Read More

    Scabies Surrepticius: Scabies Masquerading as Pityriasis Rosea.
    Cureus 2017 Dec 19;9(12):e1961. Epub 2017 Dec 19.
    Department of Dermatology, University of California, San Diego.
    Scabies, a mite infestation caused by 'Sarcoptes scabiei', most commonly presents as pruritic linear burrows where the mite has invaded the skin. Scabies variant such as bullous, crusted, hidden, incognito, nodular and scalp-mimic the other conditions. In addition, atypical presentations of scabies can masquerade as dermatitis herpetiformis, ecchymosis, Langerhans cell histiocytosis, systemic lupus erythematosus, urticaria, and urticaria pigmentosa. Read More

    Design of a Topically Applied Gel Spray Formulation with Ivermectin Using a Novel Low Molecular Weight Gelling Agent, Palmitoyl-Glycine-Histidine, to Treat Scabies.
    Chem Pharm Bull (Tokyo) 2018 ;66(3):327-333
    Graduate School of Pharmaceutical Sciences, Josai University.
    Palmitoyl-glycine-histidine (Pal-GH) is a new low molecular weight gelling agent. It exhibits thixotropic behavior, low viscosity, and high dissolving properties for a wide range of hydrophilic to lipophilic drugs. Orally administered ivermectin (IVM) is used to treat scabies. Read More

    [Outbreaks of Scabies in Schools and Use of Ivermectin].
    Gesundheitswesen 2018 Apr 19;80(4):360-364. Epub 2018 Feb 19.
    Amt für Gesundheit Plön, Leitung.
    Background: At Pentecost 2017 outbreaks of scabies occurred in three schools in Ploen County. Several classes were supposed to go on an excursion or had returned from an excursion with symptomatic kids.

    Methods: Rapid investigation, on site outbreak confirmation, home visits of the environment of the index cases, simultaneous mass treatment and post exposure prophylaxis (PEP) with Ivermectin according to the outbreak characteristics were applied. Read More


    Scabies is strongly associated with acute rheumatic fever in a cohort study of Auckland children.
    J Paediatr Child Health 2018 Feb 14. Epub 2018 Feb 14.
    Human Potential Centre, Millennium Institute, Auckland University of Technology, Auckland, New Zealand.
    Aim: This study sought to determine whether scabies infection is associated with acute rheumatic fever (ARF) or chronic rheumatic heart disease (CRHD).

    Methods: A cohort study was undertaken using health records of children aged 3-12 years attending an oral health service for the first time. Subjects were then linked to hospital diagnoses of scabies and ARF or CRHD. Read More

    Management of a family outbreak of scabies with high risk of spread to other community and hospital facilities.
    Am J Infect Control 2018 Jan 31. Epub 2018 Jan 31.
    Department of Biomedical and Neuromotor Sciences, Unit of Hygiene, Public Health and Medical Statistics, University of Bologna, Bologna, Italy.
    Background: In developed countries, scabies is observed sporadically or as institutional outbreaks in hospitals and other health facilities. In the family context, outbreaks generally involve a limited number of cases.

    Methods: A local health authority in Emilia-Romagna (Northern Italy) carried out an epidemiologic investigation on a family outbreak of scabies that included an unusually high number of cases. Read More

    Impact of climate change on dermatological conditions related to flooding: update from the International Society of Dermatology Climate Change Committee.
    Int J Dermatol 2018 Jan 29. Epub 2018 Jan 29.
    Department of Dermatology, Mayo Clinic in Minnesota, Rochester, Minnesota, USA.
    Climate change contributes to the increase in severity and frequency of flooding, which is the most frequent and deadly disaster worldwide. Flood-related damage can be very severe and include health effects. Among those health impacts, dermatological diseases are one of the most frequently encountered. Read More

    Clinicopathological features and course of cutaneous protothecosis.
    J Eur Acad Dermatol Venereol 2018 Jan 22. Epub 2018 Jan 22.
    Department of Dermatology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
    Background: Protothecosis is an uncommon infection caused by the achlorophyllic algae found more commonly in tropical areas. Only a limited number of cases have been reported.

    Objective: We aimed to evaluate the clinicopathological features and treatment outcomes of cutaneous protothecosis. Read More

    Increased risk of psoriasis following scabies infection: A nationwide population-based matched-cohort study.
    J Dermatol 2018 Mar 21;45(3):302-308. Epub 2018 Jan 21.
    Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan.
    Both scabies and psoriasis are pruritic inflammatory skin diseases. The clinical manifestations are similar and provocation of psoriasis by mite bite was reported. The association between scabies and psoriasis was not investigated before. Read More

    A UPLC-MS/MS method for simultaneous determination of five flavonoids from Stellera chamaejasme L. in rat plasma and its application to a pharmacokinetic study.
    Biomed Chromatogr 2018 Jan 12. Epub 2018 Jan 12.
    Department of Pharmacy, Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai, China.
    Stellera chamaejasme L. has been used as a traditional Chinese medicine for the treatment of scabies, tinea, stubborn skin ulcers, chronic tracheitis, cancer and tuberculosis. A sensitive and selective ultra-high liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed and validated for the simultaneous determination of five flavonoids (stelleranol, chamaechromone, neochamaejasmin A, chamaejasmine and isochamaejasmin) of S. Read More

    A Case Report of Real-Time in vivo Demonstration of Sarcoptes scabiei.
    Turkiye Parazitol Derg 2017 Dec;41(4):229-232
    Clinic of Dermatology, İstanbul Medeniyet University, Göztepe Training and Research Hospital, İstanbul, Turkey.
    Scabies is a pruritic dermatosis caused by the ectoparasite Sarcoptes scabiei var. hominis. The diagnosis of scabies is usually made on clinical grounds, but histopathological and/or dermoscopic examinations may sometimes be of assistance. Read More

    Sarcoptes scabiei on hedgehogs in New Zealand.
    Parasitol Res 2018 Mar 9;117(3):697-703. Epub 2018 Jan 9.
    School of Veterinary Science, Massey University, Palmerston North, New Zealand.
    European hedgehogs (Erinaceus europaeus) were introduced into New Zealand from Britain during the period from 1869 to the early 1900s. The only mite found on New Zealand hedgehogs in early studies was Caparinia tripilis, with Sarcoptes scabiei first being reported in 1996. The aim of this study was to investigate the prevalence of Sarcoptes infestation on hedgehogs in New Zealand, the number of mites found and the degree of mange observed. Read More

    Genetic background affects pathogenicity island function and pathogen emergence in Streptomyces.
    Mol Plant Pathol 2018 Jan 9. Epub 2018 Jan 9.
    Department of Plant Pathology, University of Florida, Gainesville, FL, 32611, USA.
    With few exceptions, thaxtomin A (ThxA), a nitrated diketopiperazine, is the pathogenicity determinant for plant-pathogenic Streptomyces species. In Streptomyces scabiei (syn. S. Read More

    The coronafacoyl phytotoxins: structure, biosynthesis, regulation and biological activities.
    Antonie Van Leeuwenhoek 2018 May 6;111(5):649-666. Epub 2018 Jan 6.
    Department of Biology, Memorial University of Newfoundland, St. John's, NL, A1B 3X9, Canada.
    Phytotoxins are secondary metabolites that contribute to the development and/or severity of diseases caused by various plant pathogenic microorganisms. The coronafacoyl phytotoxins are an important family of plant toxins that are known or suspected to be produced by several phylogenetically distinct plant pathogenic bacteria, including the gammaproteobacterium Pseudomonas syringae and the actinobacterium Streptomyces scabies. At least seven different family members have been identified, of which coronatine was the first to be described and is the best-characterized. Read More

    Lakartidningen 2017 Nov 7;114. Epub 2017 Nov 7.
    Statens Veterinärmedicinska Anstalt - Avdelningen för djurhälsa och antibiotikafrågor Uppsala, Sweden Statens Veterinärmedicinska Anstalt - Avdelning för djurhälsa och antibiotikafrågor Uppsala, Sweden.
    In case of pruritus, always consider scabies! Scabies is an itching skin disease caused by the mite Sarcoptes scabiei which affects more than 100 million people worldwide. Regarded as a neglected tropical disease by the WHO, it is a major public health burden in endemic areas. As direct skin-to-skin contact is the main route of transmission family members and sexual partners are often affected. Read More

    Scabies, crusted (Norwegian) scabies and the diagnosis of mite sensitisation.
    Allergol Immunopathol (Madr) 2018 May - Jun;46(3):276-280. Epub 2017 Dec 24.
    Allergy and Clinical Immunology Department, Centro Médico Docente La Trinidad, Caracas, Venezuela.
    Scabies is observed with relatively high frequency in Allergy and Dermatology clinics in developing countries where poor sanitary conditions are prevalent and increasingly in some areas of the world with increased immigrant populations. Since the immunological response to scabies mites includes the production of IgE class antibodies to Sarcoptes scabiei allergens which cross-react with Dermatophagoides major allergens Der p 1 and Der p 2, positive immediate-type skin tests to house dust mite extracts should be interpreted cautiously. Additionally, scabies should be included routinely in the differential diagnosis of itchy rashes in patients living in those areas. Read More

    What's eating you? scabies in the developing world.
    Cutis 2017 Nov;100(5):287-289
    Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, USA.
    Scabies infestation is a major cause of impetigo and subsequent renal failure in the developing world, and efforts to eradicate widespread infestation are underway. Ivermectin, topical sulfur, and topical benzyl benzoate often are used to treat widespread outbreaks. Read More

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