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J Ethnopharmacol 2018 Dec 5. Epub 2018 Dec 5.

Biomedical Research Center, Institute of Virology, Slovak Academy of Sciences, Dúbravská cesta 9, 845 05 Bratislava, Slovakia.

Ethnopharmacological Relevance: Essential oils and essential oil bearing medicinal and culinary plants have a long tradition of being used to combat infection, treat various conditions, and promote and restore health. Mint oils are traditionally applied to repel insects and treat various conditions including wounds, skin infections, inflammation, eczema, urticaria, psoriasis, scabies and insect bites. They are among essential oils promoted as a natural way to prevent tick-borne diseases and recommended as ingredients in various homemade repellent mixtures and tick-bite treatments. Read More

Am J Infect Control 2018 Dec 5. Epub 2018 Dec 5.

Division of Infectious Diseases, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.

Scabies is a re-emerging parasitic disease, particularly in hospitalized patients. This is a retrospective study analyzing adult patients with scabies admitted to a referral university hospital between 2008 and 2018. All patients were treated an average of 3 times using scabicides; the median isolation period and time to cure were 14 and 15 days, respectively. Read More

Lancet Infect Dis 2018 Dec;18(12):1310

Department of Dermatology, CHU Rennes, Rennes, France.

Lancet Infect Dis 2018 Dec;18(12):1309-1310

Office for Infection Control, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, South Korea; Department of Infectious Diseases, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, South Korea. Electronic address:

Lancet Infect Dis 2018 Dec;18(12):1308-1309

East of England Health Protection Team, Goodman House, Harlow, Essex CM20 2ET, UK.

Pathology 2018 Nov 28. Epub 2018 Nov 28.

Department of Medicine, Cairns Hospital, Cairns, Qld, Australia; The Kirby Institute, University of New South Wales, Kensington, NSW, Australia.

Human T-lymphotropic virus type 1 (HTLV-1) is hyperendemic amongst Indigenous Australians living in Central Australia. The epidemiology of the disease is poorly defined in other parts of Australia, despite a high prevalence of classically associated conditions. All HTLV-1 serology tests requested through public health facilities in Far North Queensland (FNQ) from January 1999 to December 2016 were reviewed. Read More

Sex Health 2018 Dec 6. Epub 2018 Dec 6.

Rates of sexually transmissible infections (STIs) have increased over recent years among gay men and other men who have sex with men (MSM) in England and Wales. HIV diagnoses remain high in this group and men with diagnosed HIV are disproportionally affected by STIs. MSM are therefore a priority for health promotion efforts to reduce STIs. Read More

Rev Prat 2017 12;67(10):1076-1079

Service de dermatologie, CHU de Brest, Brest, France.

Pruritus of the elderly. Pruritus is defined as an unpleasant sensation that causes the need for scratching. In the elderly, it is frequently encountered. Read More

BMC Dermatol 2018 Dec 4;18(1):11. Epub 2018 Dec 4.

Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology laboratory, Mahosot Hospital, Vientiane, Laos.

Background: Skin diseases are common and often have an impact on an individual's health-related quality of life. In rural communities where access to healthcare may be limited and individuals rely on farming for food and income, the impact of skin diseases may be greater. The objectives for this study were to perform an assessment of skin disease prevalence in a rural village in Laos and assess the associated impact of any skin disease found using the Dermatology Life Quality Index (DLQI). Read More

Iran J Parasitol 2018 Jul-Sep;13(3):466-472

Dept. of Animal Health, Faculty of Vocational, Universitas Airlangga, Surabaya, Indonesia.

Background: Scabies or mange is an infectious skin disease caused by the mite . This skin disease affects various livestock such as goats, sheep, swine, cattle, other animals like dogs, cats, wild animals and also affect human. This research aimed to explore the protein in mites which has antigenic character and play roles in scabies pathogenesis in goats and rabbits. Read More

J Dtsch Dermatol Ges 2018 Nov 27. Epub 2018 Nov 27.

Institute of Microbiology and Hygiene, Charité - University Medicine, Berlin, Germany.

Scabies has been diagnosed surprisingly frequently in Germany in recent years, and the use of acaricides has risen markedly. Present figures indicate an increase in the prevalence/incidence of scabies, but do not prove or quantify it for the following reasons: (a) scabies is not a notifiable disease in Germany; (b) the diagnosis is not always confirmed lege artis by means of light microscopy or dermatoscopy (which may lead to a comparatively high proportion of false-positive diagnoses due to the low overall prevalence of scabies); (c) repeated treatments of the same patient and treatment of contact persons are included in the total number of prescriptions. Therefore, there are no valid data on disease occurrence, either in the current situation or from previous periods. Read More

EJIFCC 2018 Nov 7;29(3):171-174. Epub 2018 Nov 7.

Department of Parasitology, Faculty of Medicine, University of Manisa Celal Bayar, Manisa, Turkey.

Economic instability, destabilisation with armed conflagration, religious and ethnic conflicts are the most important driving factors for migrations towards Europe. Mediterranean countries are important route for refugees who emigrate from the Middle East, Africa and Asia. Viral, bacterial, parasitic and fungal diseases carried by these refugees constitute a significant health risk in Mediterranean countries. Read More

Med Mal Infect 2018 Nov 22. Epub 2018 Nov 22.

INTHERES, université de Toulouse, INRA, ENVT, 23 chemin des Capelles, 31300 Toulouse, France.

Lancet Infect Dis 2018 Nov 21. Epub 2018 Nov 21.

Department of Primary Care and Public Health, Brighton and Sussex Medical School, Falmer, UK; Public Health England South East, Horsham, UK.

Parasit Vectors 2018 Nov 20;11(1):599. Epub 2018 Nov 20.

Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, China.

Background: Scabies is caused by Sarcoptes scabiei burrowing into the stratum corneum of the host's skin and is detrimental to the health of humans and animals. Vaccines are an attractive alternative to replace the acaricides currently used in their control.

Methods: In the present study, the S. Read More

Korean J Pediatr 2018 Nov 9;61(11):371-373. Epub 2018 Nov 9.

Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Scabies is a highly contagious skin infestation caused by the mite, Sarcoptes scabiei var. hominis. Complex responses to scabies mites in the innate, humoral, and cellular immune systems can cause skin inflammation and pruritus. Read More

Cien Saude Colet 2018 Nov;23(11):3587-3596

Departamento de Saúde Coletiva, Faculdade de Ciências Médicas, Universidade Estadual de Campinas. R. Tessália Vieira de Camargo 126, Cidade Universitária Zeferino Vaz. 13083-887 Campinas SP Brasil.

Mental disorders are present in four of the ten main causes of incapacity across the world. This article aims to analyze the prevalence of Common Mental Disorders (CMD) in incarcerated women and associated factors. A cross-sectional study was conducted with a population of 1,013 women incarcerated in a female prison. Read More

J Cutan Pathol 2018 Dec;45(12):877-879

Rutgers - Robert Wood Johnson Medical School, Department of Dermatology, Somerset, New Jersey, USA.

J Dtsch Dermatol Ges 2018 Dec 12;16(12):1451-1456. Epub 2018 Nov 12.

Department of Dermatology and Venerology, Medical Center - University of Freiburg and Medical Faculty, University of Freiburg, Germany.

Background And Objectives: Recently, there have been increasing numbers of patients consulting emergency units in all medical disciplines. Our aim was to analyze the demographics, referral mode, symptoms, localization of lesions, prior treatment, diagnoses and hospitalization rate of dermatological patients.

Patient And Methods: The study was conducted as a prospective single center survey over six months in the dermatology unit of a university hospital in Germany. Read More

JAAD Case Rep 2018 Nov 30;4(10):985-987. Epub 2018 Oct 30.

Department of Dermatology, University of California, Irvine, California.

Trop Med Infect Dis 2018 Nov 2;3(4). Epub 2018 Nov 2.

Charité-University Medicine Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 12203 Berlin, Germany.

Scabies is a neglected tropical disease associated with important morbidity. The disease occurs worldwide and is particularly common in resource-poor communities in the Global South. A validated technique for the diagnosis of scabies in resource-poor settings does not exist. Read More

J Invest Dermatol 2018 Nov 2. Epub 2018 Nov 2.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA; Miami Itch Center, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address:

Trop Med Infect Dis 2018 Oct 29;3(4). Epub 2018 Oct 29.

Amhara Regional Health Bureau, P.O. Box 744, Amhara, Ethiopia.

The impact of the severe drought in Ethiopia, attributed to El Niño weather conditions, has led to high levels of malnutrition that have, in turn, increased the potential for disease outbreaks. In 2015, Ethiopia faced a scabies outbreak in drought-affected areas where there was a shortage of safe water for drinking and personal hygiene. Following a house-to-house census to assess the prevalence of scabies, a detailed study was conducted looking at the disease burden. Read More

Br J Dermatol 2018 Oct 30. Epub 2018 Oct 30.

Department of Dermatology, Rouen University Hospital University of Rouen Normandie, Rouen.

Background: Treatment failure, which occurs in about one-third of cases, is considered as a major factor in the increasing incidence of scabies in developed countries.

Objective: To identify predictors of treatment failure of scabies in ambulatory populations.

Methods: This multicentre study compared the clinical characteristics and treatment modalities between a group of patients with scabies treated successfully and another group who were not cured 3 months after anti-scabies treatment. Read More

J Drugs Dermatol 2018 Oct;17(10):1131-1133

Crusted scabies (CS) is a highly infectious hyperinfestation variant of scabies with up to millions of Sarcoptes scabiei mites present on the skin surface. Diagnostic clues include intense itching and thick crusting especially on the face, groin, and buttocks, although variable presentations may mimic other dermatoses. CS has been associated with immunosuppression including the human immunodeficiency virus (HIV) and lymphoreticular malignancies. Read More

Theriogenology 2019 Jan 27;124:32-38. Epub 2018 Sep 27.

Department of Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, Av. Prof. Dr. Orlando Marques de Paiva, 87, São Paulo, SP, 05508-270, Brazil.

Ivermectin (IVM) is a macrocyclic lactone used as a broad spectrum antiparasitic agent against nematodes and arthropods. It is mainly used in the control of parasitic infections of domestic animals, and recently has been used in humans to treat onchocerciasis, scabies, and pediculosis. In mammals, evidence has indicated that macrocyclic lactones interact with gamma-aminobutyric acid (GABA)-mediated chloride channels. Read More

Int J Dermatol 2018 Oct 15. Epub 2018 Oct 15.

Medical Microbiology and Mycology Laboratory, El Bosque University, Bogota, Cundinamarca, Colombia.

Lancet Infect Dis 2018 Oct;18(10):1068

School of Civil Engineering, University of Leeds, Leeds LS2 9JT, UK. Electronic address:

Lancet Infect Dis 2018 Oct;18(10):1068-1069

Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.

Pediatr Infect Dis J 2018 Oct 5. Epub 2018 Oct 5.

G Ital Dermatol Venereol 2018 Oct 3. Epub 2018 Oct 3.

Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.

Trop Med Infect Dis 2018 Sep 5;3(3). Epub 2018 Sep 5.

Tropical Diseases, Murdoch Children's Research Institute, Parkville VIC 3052, Australia.

Scabies is a neglected tropical disease of the skin, causing severe itching and stigmatizing skin lesions. Further, scabies leads to impetigo, severe bacterial infections, and post-infectious complications. Around 200 million people are affected, particularly among disadvantaged populations living in crowded conditions in tropical areas. Read More

Trop Med Infect Dis 2018 Aug 3;3(3). Epub 2018 Aug 3.

Department of Dermatology and Mycology Acapulco General Hospital, Health Secretary Guerrero, Community Dermatology Mexico C.A., 39355 Acapulco, Guerrero, Mexico.

The uncontrolled sale of topical corticosteroids has become an important risk factor for the development of iatrogenic Cushing syndrome in children, especially in countries where medications are sold over the counter. This is exacerbated by the lack of information for both the patients and pharmacists. This report documents a series of eight cases of iatrogenic Cushing syndrome secondary to an inappropriate use of topical steroids, due to a misdiagnosis of scabies. Read More

Trop Med Infect Dis 2018 Jun 4;3(2). Epub 2018 Jun 4.

Department of Community Health, School of Medicine, Federal University of Ceará, Fortaleza CE 60430-140, Brazil.

Epidemiology and clinical features of scabies remain largely unknown in Nigeria's rural communities. To fill this gap, we performed a cross-sectional study in three rural communities in north central Nigeria. A total of 500 individuals were included and examined for scabies infestation; a questionnaire was applied to collect socio-demographic and behavioral data. Read More

Trop Med Infect Dis 2018 Jan 29;3(1). Epub 2018 Jan 29.

School of Health, Medical and Applied Sciences, Central Queensland University, Bundaberg, QLD 4670, Australia.

Background: Education for health literacy of Australian Aboriginal people living remotely is challenging as their languages and worldviews are quite different from English language and Western worldviews. Becoming health literate depends on receiving comprehensible information in a culturally acceptable manner.

Methods: The study objective was to facilitate oral health literacy through community education about scabies and strongyloidiasis, including their transmission and control, preceding an ivermectin mass drug administration (MDA) for these diseases. Read More

PLoS Negl Trop Dis 2018 Sep 25;12(9):e0006825. Epub 2018 Sep 25.

Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Background: Scabies and head lice are ubiquitous ectoparasitic infestations that are common across the Pacific Islands. Ivermectin is an effective treatment for both conditions, although the doses used vary. At a community level, mass drug administration (MDA) with ivermectin is an effective strategy to decrease prevalence of scabies. Read More

Int J Dermatol 2018 Sep 24. Epub 2018 Sep 24.

Head of the Pediatrics Department, Hospital Interzonal General de Agudos Presidente Perón, Sarandí, Avellaneda, Buenos Aires, Argentina.

Background: Infectious skin disorders (ISDs) are commonly seen in pediatric emergency departments (PED), however the exact frequency is unknown. We provide an accurate evaluation of the incidence and characteristics of ISDs diagnosed in a PED from Buenos Aires, Argentina, over a 1-year period.

Methods: Prospectively, descriptive study of children evaluated in the PED with ISDs during 2016. Read More

J Proteome Res 2018 Nov 10;17(11):3837-3852. Epub 2018 Oct 10.

Laboratory for Microbiology, Department of Biochemistry and Microbiology , Ghent University , B-9000 Ghent , Belgium.

Streptomyces scabies is responsible for common scab disease on root and tuber vegetables. Production of its main phytotoxin thaxtomin A is triggered upon transport of cellulose byproducts cellotriose and cellobiose, which disable the repression of the thaxtomin biosynthesis activator gene txtR by the cellulose utilization regulator CebR. To assess the intracellular response under conditions where S. Read More

Lancet Glob Health 2018 Oct;6(10):e1132-e1138

The Kirby Institute, University of New South Wales, Sydney, NSW, Australia.

Background: Mass drug administration has made a major contribution to the public health control of several important neglected tropical diseases. For settings with more than one endemic disease, combined mass drug administration has potential practical advantages compared with separate programmes but needs confirmation of feasibility and safety. We undertook a study of mass drug administration in the Solomon Islands for trachoma and scabies control using ivermectin and azithromycin, key drugs in the control of neglected tropical diseases worldwide. Read More

Genomics 2018 Sep 15. Epub 2018 Sep 15.

Department of Microbiology and Immunology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan. Electronic address:

Sarcoptes scabiei (Acari: Sarcoptidae) causes a common contagious skin disease that affects many mammals. Here, the complete mitochondrial genome of a mite, S. scabiei var. Read More

Br J Dermatol 2018 Sep;179(3):e133

Faculty of Medicine, School of Health Sciences, University Ioannina Medical School - Skin & Venereal Diseases, University of Ioannina, University Campus Ioannina, Ioannina, GR-45110, Greece.

PLoS One 2018 17;13(9):e0203684. Epub 2018 Sep 17.

Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, The University of Western Australia, Perth, Western Australia, Australia.

Infectious diseases contribute a substantial burden of ill-health in Australia's Aboriginal children. Skin infections have been shown to be common in remote Aboriginal communities, particularly in the Northern Territory, Australia. However, primary care data on skin and other infectious diseases among Aboriginal children living in remote areas of Western Australia are limited. Read More

Ned Tijdschr Geneeskd 2018 08 23;162. Epub 2018 Aug 23.

Erasmus MC, afd. Maatschappelijke Gezondheidszorg, Rotterdam.

The number of asylum seekers entering the Netherlands has increased. However, the screening, detection and treatment of infectious diseases in asylum seekers has barely changed over the last 15 years. Infectious diseases, including vaccine-preventable diseases are being carried into the Netherlands by asylum seekers. Read More

Indian J Sex Transm Dis AIDS 2018 Jan-Jun;39(1):44-49

Department of Skin and VD, Rajindra Hospital, GMC, Patiala, Punjab, India.

Context: Pruritic papular eruption (PPE) is a chronic eruption of papular and pruritic lesions of unknown etiology, symmetrically distributed over trunk and extremities. These are common cutaneous manifestations in HIV patients. It is an important cause of HIV-related morbidity. Read More

PLoS One 2018 31;13(8):e0200433. Epub 2018 Aug 31.

Molecular Parasitology Laboratory, Immunology Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia.

EgKI-1, a member of the Kunitz type protease inhibitor family, is highly expressed by the oncosphere of the canine tapeworm Echinococcus granulosus, the stage that is infectious to humans and ungulates, giving rise to a hydatid cyst localized to the liver and other organs. Larval protoscoleces, which develop within the hydatid cyst, have been shown to possess anti-cancer properties, although the precise molecules involved have not been identified. We show that recombinant EgKI-1 inhibits the growth and migration of a range of human cancers including breast, melanoma and cervical cancer cell lines in a dose-dependent manner in vitro without affecting normal cell growth. Read More

N Z Med J 2018 Aug 31;131(1481):78-81. Epub 2018 Aug 31.

Medical Officer, Auckland Regional Public Health Service, Greenlane Clinical Centre, Greenlane West, Auckland.

Math Biosci 2018 Aug 24. Epub 2018 Aug 24.

School of Mathematics and Statistics, The University of Melbourne, Australia; Melbourne School of Population and Global Health, The University of Melbourne, Australia; Peter Doherty Institute for Infection and Immunity, The Royal Melbourne Hospital and The University of Melbourne, Australia; Murdoch Childrens Research Institute, The Royal Children's Hospital, Melbourne, Australia. Electronic address:

Infections with Sarcoptes scabiei, or scabies, remain common in many disadvantaged populations. Mass drug administration (MDA) has been used in such settings to achieve a rapid reduction in infection and transmission, with the goal of eliminating the public health burden of scabies. While prevalence has been observed to fall substantially following such an intervention, in some instances resurgence of infection to baseline levels has occurred over several years. Read More

Indian J Sex Transm Dis AIDS 2017 Jul-Dec;38(2):128-135

Department of Community Medicine, Government Villupuram Medical College and Hospital, Villupuram, Tamil Nadu, India.

Background: Mucocutaneous findings may be the presenting symptoms in HIV-afflicted individuals. A multitude of mucocutaneous diseases also occurs during the course of the ailment, with some conditions being classed as disease defining. They include infectious diseases and noninfective inflammatory and neoplastic dermatoses. Read More

J Ethnopharmacol 2018 Dec 23;227:41-55. Epub 2018 Aug 23.

Department of Toxicology, School of Public Health, Peking University, No. 38 Xueyuan Road, Haidian District, Beijing 100191, China; Key Laboratory of State Administration of Traditional Chinese Medicine for Compatibility Toxicology, Beijing 100191, China; Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Beijing 100191, China. Electronic address:

Ethnopharmacological Relevance: Euphorbia semen, the dried and ripe seed of Euphorbia lathyris Linnaeus, is widely cultivated for traditional medicine use. This semen is used to expel water, help with phlegm retention, promote blood circulation, remove blood stasis, cure tinea and scabies, and treat amenorrhea, snakebites, terminal schistosomiasis, anuria and constipation.

Aim Of The Review: This review provides updated, comprehensive and categorized information on the local and traditional uses, phytochemistry, pharmacokinetics, pharmacological activities and toxicity of Euphorbia semen. Read More

Dermatol Online J 2018 May 15;24(5). Epub 2018 May 15.

Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.

Scabies is an infestation of Sarcoptes scabiei resulting in intensely pruritic erythematous papules tipped with hemorrhagic crusts. Current guidelines and medication labels instruct application of topical permethrin 5% cream from neck down for treatment of adult patients with scabies. Although scalp and head involvement are observed in infants, it is rare in older children and adults. Read More