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Dermatol Ther 2020 Jul 4:e13954. Epub 2020 Jul 4.

Department of Community Medicine, Hamdard Institute of Medical Sciences and Research & HAH CENTENARY Hospital, Jamia Hamdard, Hamdard Nagar, New Delhi.

Objective: The aim of this study was to compare the efficacy and safety of 0.1% triamcinolone acetonide and 0.1% tacrolimus ointment for the treatment of such nodular lesions of scabies. Read More

J Infect Dev Ctries 2020 Jun 29;14(6.1):78S-85S. Epub 2020 Jun 29.

Department of dermatology, Amsterdam Institute for Infection and Immunity (AI and II), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

Introduction: After a scabies outbreak in Amhara Region, Ethiopia in 2015/2016, the Regional Health Bureau performed an extensive Mass Drug Administration (MDA). In May 2017, we collected data to assess the impact of the treatment on the scabies control.

Methodology: We retrieved baseline data from the 2015/16 burden assessment: campaign organization and administration information. Read More

J Infect Dev Ctries 2020 Jun 29;14(6.1):48S-52S. Epub 2020 Jun 29.

Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

Introduction: Orphans are at high risk for neglected tropical diseases (NTDs) and other comorbidities such as malnutrition. We investigated how many orphans suffered from scabies, other NTDs and malnutrition.

Methodology: A descriptive study using medical records of orphans referred to a teaching hospital in Addis Ababa, Ethiopia from December 2014 to December 2018 was done. Read More

J Infect Dev Ctries 2020 Jun 29;14(6.1):36S-41S. Epub 2020 Jun 29.

UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), World Health Organization, Geneva, Switzerland.

Introduction: In 2017, Ethiopia included scabies management within the responsibility of health extension workers. In Kamba (the intervention district) workers were trained on scabies management. Whereas, in Arba Minch Zuria (the control district) there was no such training. Read More

J Infect Dev Ctries 2020 Jun 29;14(6.1):28S-35S. Epub 2020 Jun 29.

UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), World Health Organization, Geneva, Switzerland.

Introduction: In 2018, the Ethiopian Ministry of Health embarked on a Mass Drug Administration (MDA) campaign that involved over 9 million people in Ethiopia - the largest scabies MDA campaign ever conducted on a global level. We describe its implementation and report on a) numbers screened and identified with scabies, b) treatment category and drug type and c) human resources used, duration, and cost of the campaign.

Methodology: The MDA campaign was conducted according to national guidelines and activities including: planning and organization, engagement of local leaders, community mobilisation and advocacy, awareness-raising among health workers, field implementation, and monitoring and evaluation. Read More

J Infect Dev Ctries 2020 Jun 29;14(6.1):16S-21S. Epub 2020 Jun 29.

Institute of Tropical Medicine, Antwerp, Belgium.

Introduction: The majority of neglected tropical diseases (NTDs) have established primary skin manifestations or associated clinical feature. Skin NTDs often result in physical impairment and disfigurement, which can lead to disability. Skin diseases have been proposed as an entry point for integrated NTDs control. Read More

JAAD Case Rep 2020 Jul 19;6(7):640-642. Epub 2020 May 19.

Department of Dermatology, University of California, Irvine, California.

Dermatol Ther 2020 Jun 30. Epub 2020 Jun 30.

Department of Dermatology, Greys Hospital, Nelson R Mandela School of Medicine, University of KwaZulu- Natal, South Africa.

Br J Dermatol 2020 Jun 28. Epub 2020 Jun 28.

Department of Dermatology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.

Dear Editor, Scabies infestation is increasingly a public health concern, even in high-income countries. The disability-adjusted life-years (DALYs) globally was estimated to be 71·11 (95% CI 39·77-116·03) per 100,000 people based on the results of a cross-sectional analysis from the Global Burden of Disease Study 2015 . The gold standard for scabies diagnosis is microscopic examination of skin scrapings in mineral oil, but the sensitivity of this technique is low ; as a result, scabies infestation cannot be ruled out even when this test is negative. Read More

J Am Acad Dermatol 2020 Jun 25. Epub 2020 Jun 25.

Apex Dermatology and Skin Surgery Center, Mayfield Heights, OH; Lake Erie College of Osteopathic Medicine, Erie, PA.

PLoS Negl Trop Dis 2020 Jun 26;14(6):e0008423. Epub 2020 Jun 26.

Centre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon.

Background: It is unclear whether individual treatment of scabies is similarly effective compared to household treatment. This study compared these two treatment strategies with topical benzyl benzoate for treating scabies in Lambaréné, Gabon.

Methods: Participants presenting with uncomplicated scabies were randomized into either the Individual Treatment group, where only the affected participants received treatment, or the Household Treatment group, where all family members were treated in parallel to the affected participants regardless of signs and symptoms. Read More

Aust J Rural Health 2020 Jun 23. Epub 2020 Jun 23.

Royal Darwin Hospital, Tiwi, NT, Australia.

Objective: To assess the objective evidence upon which diagnosis of scabies and subsequent prescription of permethrin cream or oral ivermectin is based at a tertiary referral hospital in the Northern Territory.

Design, Setting And Participants: A retrospective cohort study of inpatients who were prescribed permethrin or ivermectin between July and September 2017 at a single tertiary referral hospital. Eighty-eight inpatient admissions, belonging to 77 unique patients, were included. Read More

J Cutan Med Surg 2020 Jun 22:1203475420936642. Epub 2020 Jun 22.

8788 Department of Dermatology, University of California, Irvine, CA, USA.

J Formos Med Assoc 2020 Jun 17. Epub 2020 Jun 17.

Department of Obstetrics and Gynecology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address:

Background/purpose: Population aging and unequal accessibility of health care are increasingly important in developed countries. One strategy to overcome these issues is utilizing telemedicine, which is recently made possible technologically by the advancement of internet speed, high speed zooming cameras, and the information storages. In Taiwan, the telemedicine is granted legally by the amendment for Taiwan's Physician Act in 2018. Read More

Age Ageing 2020 Jun 18. Epub 2020 Jun 18.

Department of Dermatology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.

Australas J Dermatol 2020 Jun 16. Epub 2020 Jun 16.

Northern Clinical School, University of Sydney, Sydney, NSW, Australia.

Background: There is limited information about the type of skin disease in Timor-Leste. In order to determine the type and magnitude of skin disease in Timor-Leste, we conducted a cross-sectional point prevalence study of 271 patients from rural and urban Timor-Leste. The aim of the study was to estimate the magnitude and burden of dermatological disease. Read More

Biomol Ther (Seoul) 2020 Jun 15. Epub 2020 Jun 15.

College of Pharmacy, Gachon University, Incheon 21936, Republic of Korea.

Crotamiton is an anti-scabies drug, but it was recently found that crotamiton also suppresses non-scabietic itching in mice. However, the underlying mechanism is largely unclear. Therefore, aim of the study is to investigate mechanisms of the anti-pruritic effect of crotamiton for non-scabietic itching. Read More

Pediatr Dermatol 2020 Jun 10. Epub 2020 Jun 10.

Department of Dermatology, University of Massachusetts Medical School, Worcester, MA, USA.

Background: Current literature addressing dermatologic conditions associated with Down syndrome is limited, with emphasis on rare skin conditions and lack of consensus on the incidence of more common disorders.

Objective: We sought to evaluate dermatologic conditions in patients with Down syndrome diagnosed and managed by dermatologists.

Methods: This was a retrospective analysis of 101 pediatric and adult patients with Down syndrome seen by the University of Massachusetts Dermatology Department between 2008 and 2018. Read More

BMC Pediatr 2020 Jun 9;20(1):284. Epub 2020 Jun 9.

Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

Background: Histoplasmosis is a rare infectious condition with mainly pulmonary involvement. Disseminated histoplasmosis may occur in immunocompromised condition. It can present in different ways but jaundice and ascites is very uncommon. Read More

J Dermatolog Treat 2020 Jun 4:1-4. Epub 2020 Jun 4.

Department of Dermatology and Allergology, University Hospital Salzburg of the Paracelsus Medical University Salzburg, Salzburg, Austria.

Scabies is a contagious, itchy, parasitic infection of the skin. It is transmitted by skin-to-skin contact or by contact with contaminated material. Recent observations, especially in the outpatient setting, suggest there is decreasing efficacy of the standard treatment of choice, topical 5% permethrin cream. Read More

J Eur Acad Dermatol Venereol 2020 Jun 3. Epub 2020 Jun 3.

Akdeniz University Faculty of Medicine, Dermatology Department, , Antalya, Turkey.

Scabies outbreaks were reported in many countries especially from Africa, but had not been reported in Turkey before. This is a multicentre study with compiling the data of patients with scabies in 12 tertiary level dermatology clinics located in distinct geographical regions of Turkey. The medical ethical committee of Ondokuz Mayıs University Medical Faculty approved the study. Read More

J Eur Acad Dermatol Venereol 2020 Jun 2. Epub 2020 Jun 2.

Department of Dermatology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto, Japan.

Dermatol Ther 2020 Jun 2. Epub 2020 Jun 2.

University of Rome G. Marconi, Rome, Italy; Bidarskincenter Tehran, Iran.

Human scabies is a contagious skin infestation caused by the parasitic mite Sarcoptes scabiei var. hominis. It is a common skin disease worldwide that occurs not only in the underprivileged sections of society but also in developed countries. Read More

An Bras Dermatol 2020 Jul - Aug;95(4):428-438. Epub 2020 May 16.

Department of Dermatology, Faculdade de Medicina de Marília, Marília, SP, Brazil; Service of Dermatology, Secretaria Municipal de Saúde de Florianópolis, Florianópolis, SC, Brazil.

Background: Dermatology encompasses the management of many disorders of the skin and cutaneous appendages, making the analysis of epidemiological profiles relevant for health planning.

Objective: The study aims to describe the nosological profile of dermatological diseases in Florianopolis, analyzing the interrelation among the primary health care and dermatology services, from January 2016 to December 2017.

Method: Descriptive study from records of medical visits from the primary health care and dermatology services, as well as records of reports issued by the teledermatology service. Read More

Turkiye Parazitol Derg 2020 Jun;44(2):77-82

University of Health Sciences Erzurum Regional Training and Research Hospital, Clinic of Dermatology and Venereology, Erzurum, Turkey.

Objectives: We aimed to reveal the change in the demographic characteristics of patients with scabies in the last three years and the increase in frequency of patients with scabies observed in our region.

Methods: All patients diagnosed as having scabies in Erzurum Regional Training and Research Hospital and Palandöken State Hospital, Clinic of Dermatology between January 2017 and December 2019 were retrospectively evaluated. Data such as age, gender, citizenship, presentation dates were recorded from the hospital database by anonymizing. Read More

J Dtsch Dermatol Ges 2020 Jun 29;18(6):554-559. Epub 2020 May 29.

Department of Dermatology and Tropical Medicine, Military Medical Center East, Austrian Armed Forces, Vienna, Austria.

Background: In recent years, there has been a significant increase in scabies infestations throughout German-speaking countries. Given the high frequency of treatment failures, the question arises as to whether topical permethrin treatment is always performed correctly.

Patients And Methods: Our department uses a fluorescent test cream to teach patients on how to correctly apply topical permethrin. Read More

Am J Ther 2020 May 26. Epub 2020 May 26.

Department of Dermatology and Venereology, the Republic of Turkey, Health Sciences University Erzurum Regional Training and Research Hospital, Erzurum, Turkey.

BMC Infect Dis 2020 May 27;20(1):380. Epub 2020 May 27.

Department of Epidemiology and Biostatistics, School of Public health, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia.

Background: Scabies is an infectious disease that affects the skin caused by the mite Sarcoptes scabiei and it transmitted through close personal contact. Even though it is easily treatable disease, its prevalence is high and continuous as neglected tropical disease of resource-poor settings, and particularly affects young age groups. Despite of these facts, studies conducted in Ethiopia regarding to the prevalence and associated factors for scabies infestation have been highly variable and didn't well compiled. Read More

Praxis (Bern 1994) 2020 ;109(7):548-550

Institut für Dermatologie und Venerologie, Stadtspital Waid und Triemli, Zürich.

Dermatol Ther 2020 May 23:e13662. Epub 2020 May 23.

Department of Dermatology and Venereology, School of Medicine, Karabük University, Karabük, Turkey.

Hautarzt 2020 Jun;71(6):447-454

Bundeswehrkrankenhaus Ulm, Oberer Eselsberg 40, 89081, Ulm, Deutschland.

Background: The diagnosis of scabies has become surprisingly frequent in Germany in recent years and the use of scabicides has risen significantly.

Objective: The aim of our survey was to determine whether this trend can also be detected among military personnel of the German Armed Forces (Bundeswehr).

Methods: The study was conducted as a retrospective single-center study over a period of 8 years from 2012 to 2019 in the Department of Dermatology of the Armed Forces Hospital Berlin, Germany. Read More

BMJ Open 2020 May 18;10(5):e032829. Epub 2020 May 18.

Nossal Institute for Global Health, School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.

Introduction: Current evidence indicates an alarming increase in topical steroid (TS) misuse in India. Data regarding the magnitude and characteristics of this problem in rural India, where 68% of the population resides, are insufficient. This study analyses the magnitude, causes, characteristics and consequences of TS misuse in rural India. Read More

Clin Infect Dis 2020 May 18. Epub 2020 May 18.

Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, United States of America.

Prevalence of antibodies to Strongyloides stercoralis was measured in 0-12-year-olds using a bead-based immunoassay before and after ivermectin mass drug administration (MDA) for scabies in the Solomon Islands. Seroprevalence was 9.3% before and 5. Read More

J Dermatol 2020 Jul 15;47(7):e258-e260. Epub 2020 May 15.

Department of Dermatology, Nerima General Hospital, Tokyo, Japan.

Dermatol Ther 2020 May 13:e13581. Epub 2020 May 13.

Department of Dermatology, State University of New York Downstate, New York, USA.

The Coronavirus Disease 2019 (COVID-19) emerged late in Turkey but it showed a rapid progression later. We aimed to investigate the changes in the number of patients who requested a dermatology outpatient clinic visit due to the increased social and medical burden caused by COVID-19 in Turkey during the first days of the pandemic. We also examined the most common dermatologic diseases diagnosed during the COVID-19 outbreak. Read More

Ir J Med Sci 2020 May 8. Epub 2020 May 8.

Graduate Entry Medical School (GEMS), University of Limerick, Limerick, Ireland.

Background: Childhood homelessness is a growing concern in Ireland [1] creating a paediatric subpopulation at increased risk of physical illnesses, many with life-long consequences [2].

Aim: Our aim was to identify and categorize the physical morbidities prevalent in homeless children.

Methods: A review of the English-language literature on physical morbidities affecting homeless children (defined as ≤ 18 years of age) published from 1999 to 2019 was conducted. Read More

Microbiologyopen 2020 May 7:e1054. Epub 2020 May 7.

School of Medicine, Western Sydney University, Campbelltown, NSW, Australia.

Antibiotic-resistant strains of bacteria such as methicillin-resistant Staphylococcus aureus are a threat to human health, and effective treatment options against them are needed. This study aimed to determine whether the insecticide permethrin was capable of inhibiting the growth of S. aureus or if some other component of a permethrin cream was responsible for a decrease in scabies associated bacterial infection previously observed. Read More

J Dermatol 2020 Jul 7;47(7):720-727. Epub 2020 May 7.

National Sanatorium Tamazenshoen, Higashimurayama, Japan.

In Japan, pyrethroid-resistant head lice have been increasing; however, only 0.4% phenothrin, a pyrethroid drug, is available as an over the counter formulation. In recent years, Sumithrin Lotion containing 5% phenothrin (PHT) was approved for scabies. Read More

Dermatol Ther (Heidelb) 2020 May 6. Epub 2020 May 6.

Department of Dermatology and Venerology, CHU Sart Tilman, University of Liège, 4000, Liège, Belgium.

Risankizumab, an interleukin (IL)-23 antagonist, is a highly effective treatment for moderate to severe psoriasis. Crusted scabies (CS) is a rare and severe form of scabies, occurring mainly in immunosuppressed patients and/or neurologically or mentally ill patients. A young girl with Down syndrome was diagnosed with a hyperkeratotic form of psoriasis. Read More

Cureus 2020 May 2;12(5):c30. Epub 2020 May 2.

Dermatology, San Diego Family Dermatology, National City, USA.

[This corrects the article DOI: 10.7759/cureus.7419. Read More

Confl Health 2020 1;14:21. Epub 2020 May 1.

Open Arms NGO, Barcelona, Spain.

Background: The migration over the Mediterranean has become one of the deadliest sea voyages in last few years. The NGO Open Arms works in the area since 2015, with the objectives of protecting and reporting human rights at sea. This paper aims to give an overview on characteristics and health conditions of rescued people by the NGO in the Central Mediterranean. Read More

Br J Dermatol 2020 May 1. Epub 2020 May 1.

International Foundation for Dermatology, London, UK.

Scabies is one of the most common disorders identified in any estimate of global skin disease prevalence. Furthermore, quantifying its impact on individuals and societies has been problematic. There has been a lack of clear case definitions and laboratory tests. Read More

Cureus 2020 Mar 25;12(3):e7419. Epub 2020 Mar 25.

Dermatology, San Diego Family Dermatology, National City, USA.

The morphology of scabies, a mite infestation of worldwide proportion, is characterized by a variety of cutaneous lesions. Patients with classic scabies present with characteristic burrows often located on the web spaces of the fingers and toes. Scabies surrepticius refers to the non-classic atypical presentation of scabies; establishing the diagnosis of scabies in these individuals can be difficult. Read More

Praxis (Bern 1994) 2020 Apr;109(6):411-417

Institut für Dermatologie und Venerologie, Stadtspital Waid und Triemli, Zürich.

CME Dermatology 21: Scabies - Clinical Manifestation, Diagnosis and Therapy Scabies is a common contagious skin infestation found in all parts of the world affecting individuals of all ages. Its worldwide prevalence is estimated at about 200 million people at any one time. Typical manifestations consist of severe itch that is aggravated at night, and disseminated, excoriated, erythematous papules on the trunk and limbs. Read More

Mil Med 2020 Apr 28. Epub 2020 Apr 28.

Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA 92134.

Scabies outbreaks are relatively common worldwide, particularly in communal living settings such as military barracks. The infestation is caused by the parasite Sarcoptes Scabiei and is easily treated once properly diagnosed. Classic symptoms include pruritus around the waist, wrists, and ankles. Read More

J Eur Acad Dermatol Venereol 2020 Apr 27. Epub 2020 Apr 27.

Department of Dermatology, University of Lübeck, Lübeck, Germany.

Nat Prod Res 2020 Apr 21:1-6. Epub 2020 Apr 21.

Research Laboratory for Archaeology and the History of Art, University of Oxford, Oxford, UK.

Peru Balsam, a resinous substance derived from var. , has historically been used as a topical ointment for various skin conditions such as scabies, poorly healing wounds, eczema, and haemorrhoids. The ingredients responsible for these properties are not fully elucidated. Read More

Emerg Microbes Infect 2020 Dec;9(1):813-816

Department of Dermatology, Affiliated Hospital of Guizhou Medical University, Guiyang, People's Republic of China.

Scabies remains a significant public health concern globally, affecting people of all ages, races, and socioeconomic groups. The epidemic characteristics of scabies are yet unravelled, especially in high-income countries and elderly population. In this study, we sought to investigate incidence and prevalence and their trends of scabies worldwide from 1990 to 2017 via the Global Burden of Disease (GBD) Study 2017. Read More

Transpl Infect Dis 2020 Apr 10:e13284. Epub 2020 Apr 10.

Department of Clinical Microbiology, Anadolu Medical Center, Gebze, Turkey.

Background: Inpatients with crusted scabies represent an important source of nosocomial transmission with consequent outbreaks among patients and healthcare workers. This study aimed to report the course of an institutional scabies outbreak, which progressed with infestation of immunosuppressed transplant patients, health care workers, and caregivers.

Methods: Patients diagnosed with scabies in a nosocomial outbreak in a 200-bed, tertiary hospital were included. Read More

Front Microbiol 2020 26;11:495. Epub 2020 Mar 26.

Department of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom.

Bottromycin is a ribosomally synthesized and post-translationally modified peptide (RiPP) produced by several streptomycetes, including the plant pathogen . There is significant interest in this molecule as it possesses strong antibacterial activity against clinically relevant multidrug resistant pathogens and is structurally distinct from all other antibiotics. However, studies into its efficacy are hampered by poor yields. Read More