Parasit Vectors 2017 Jun 20;10(1):297. Epub 2017 Jun 20.

Department of Biological Sciences, Wright State University, 3640 Colonel Glenn Hwy, Dayton, OH, 45435, USA.

The disease scabies is one of the earliest diseases of humans for which the cause was known. It is caused by the mite, Sarcoptes scabiei, that burrows in the epidermis of the skin of humans and many other mammals. This mite was previously known as Acarus scabiei DeGeer, 1778 before the genus Sarcoptes was established (Latreille 1802) and it became S. Read More

PLoS One 2017 15;12(6):e0179537. Epub 2017 Jun 15.

Division of Infectious Diseases & Hospital Epidemiology, University Hospital Basel, University Basel, Basel, Switzerland.

Objective: The increasing number of refugees seeking asylum in Europe in recent years poses new challenges for the healthcare systems in the destination countries. The goal of the study was to describe the evolution of medical problems of asylum seekers at a tertiary care centre in Switzerland.

Methods: At the University Hospital Basel, we compared all asylum seekers during two 1-year time periods in 2004/05 and 2014/15 concerning demographic characteristics and reasons for referrals and hospitalizations. Read More

J Eur Acad Dermatol Venereol 2017 Jun 13. Epub 2017 Jun 13.

Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna.

infantile scabies sometimes manifests with atypical clinical presentation, leading to misdiagnosis. Monomorphic primary lesions or different coexisting lesions may be present. Specific pediatric localizations are scalp and face(1) , but in infants the most common are palms, soles and axillae. Read More

PLoS Negl Trop Dis 2017 Jun 12;11(6):e0005669. Epub 2017 Jun 12.

Department of Biological Sciences, Wright State University, Dayton, OH, United States of America.

Background: Scabies, caused by the mite, Sarcoptes scabiei, infects millions of humans, and many wild and domestic mammals. Scabies mites burrow in the lower stratum corneum of the epidermis of the skin and are the source of substances that are antigenic or modulate aspects of the protective response of the host. Ordinary scabies is a difficult disease to diagnose. Read More

Am J Med 2017 Jun 7. Epub 2017 Jun 7.

Division of Infectious Diseases and International Health, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Duke Clinical Research Institute, Duke University, Durham, North Carolina, USA. Electronic address:

Parasit Vectors 2017 Jun 10;10(1):289. Epub 2017 Jun 10.

QIMR Berghofer Medical Research Institute, Infectious Diseases Department, 300 Herston Road, Herston, Brisbane, 4006, Australia.

Background: Scabies is one of the most common and widespread parasitic skin infections globally, affecting a large range of mammals including humans, yet the molecular biology of Sarcoptes scabiei is astonishingly understudied. Research has been hampered primarily due to the difficulty of sampling or culturing these obligatory parasitic mites. A further and major impediment to identify and functionally analyse potential therapeutic targets from the recently emerging molecular databases is the lack of appropriate molecular tools. Read More

Medicine (Baltimore) 2017 Jun;96(23):e7108

aDivision of Urology, Department of Surgery, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan bDepartment of Medicine, National Yang-Ming University cGraduate Institute of Life Sciences dBiobank Management Center of the Tri-Service General Hospital eDepartment of Pathology and Graduate Institute of Pathology and Parasitology fDepartment of Obstetrics & Gynecology, Tri-Service General Hospital, National Defense Medical Center gInstitute of Bioinformatics and System Biology, National Chiao Tung University, Hsinchu hSchool of Chinese Medicine, College of Chinese Medicine, China Medical University iDepartment of Nursing, College of Medical and Health Science, Asia University jDepartment of Pediatrics, BinKun Women's and Children's Hospital, Taoyuan kDepartment of Pediatrics, MacKay Children's Hospital, Taipei lDepartment of Medicine, MacKay Medical College, New Taipei City mDepartment of Pediatrics and Infectious Disease, Hsinchu MacKay Memorial Hospital, Hsinchu, Taiwan nDivision of Infection and Pathway Medicine, College of Medicine and Veterinary Medicine, the University of Edinburgh, Edinburgh, United Kingdom.

Scabies is a common and distressing disease caused by the mite Sarcoptes scabiei var. hominis. Psychiatric disorder in childhood is an important disease and easily neglected. Read More

J Dermatol 2017 May 31. Epub 2017 May 31.

The Japanese Dermatological Association, Tokyo, Japan.

In the current work, we present our new guideline for the diagnosis and treatment of scabies which we, the Executive Committee convened by the Japanese Dermatological Association, developed to ensure proper diagnosis and treatment of scabies in Japan. Approval of phenothrin topical use under the National Health Insurance in August 2014 led to this action. Permethrin, a topical anti-scabietic medication belonging to the same pyrethroid group as phenothrin, is already in use worldwide. Read More

Antimicrob Agents Chemother 2017 May 30. Epub 2017 May 30.

QIMR Berghofer Medical Research Institute, Herston QLD 4006 Australia.

Moxidectin is under consideration for development as a treatment for human scabies. As some arthropods show decreased sensitivity to moxidectin relative to ivermectin, it was important to assess this for Sarcoptes scabieiIn-vitro assays showed that the concentration of moxidectin required to kill 50% of mites was lower compared to ivermectin (0.5 μM vs 1. Read More

Clin Exp Dermatol 2017 Jul 29;42(5):481-487. Epub 2017 May 29.

Department of Paediatrics, Centre for International Child Health, University of Melbourne, Melbourne, Australia.

Human scabies (infestation with the mite Sarcoptes scabiei var hominis) causes a significant disease burden worldwide, yet there are no agreed diagnostic guidelines. We aimed to determine whether a consistent approach to diagnosing scabies has been used for published scabies therapeutic trials. The data sources used were the MEDLINE, Embase and Cochrane databases, from 1946 to 29 August 2013. Read More

Actas Dermosifiliogr 2017 May 26. Epub 2017 May 26.

Facultativo Especialista de Dermatología Médico Quirúrgica y Venereología, Hospital de Alta Resolución de Alcalá la Real, Alcalá la Real, Jaén, España. Electronic address:

Trans R Soc Trop Med Hyg 2017 Mar;111(3):97-101

Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.

Background: The Solomon Islands is targeting elimination of malaria by 2030. The dominant vector is the predominantly exophagic, exophilic Anopheles farauti sensu strictu. This biting behaviour limits the efficacy of conventional vector control tools and highlights the need for new strategies. Read More

PLoS One 2017 23;12(5):e0177733. Epub 2017 May 23.

Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, China.

Scabies is a parasitic disease, caused by the mite Sarcoptes scabiei, and is considered one of the top 50 epidemic diseases and one the most common human skin disease, worldwide. Allergic dermatitis, including an intense itch, is a common symptom, however diagnosis is difficult and there is currently no effective vaccine. The goal of this study was to examine the immune interaction mechanism of both S. Read More

Indian J Dermatol Venereol Leprol 2017 Jul-Aug;83(4):492-493

Department of Dermatology, School of Medicine, Pusan National University, Busan; Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.

Pan Afr Med J 2017 3;26:125. Epub 2017 Mar 3.

The Ronald Perelman Department of Dermatology, New York University School of Medicine, USA.

Introduction: Ghana is currently developing its provision of dermatology services. Epidemiologic studies of the skin diseases seen by Ghanaian dermatologists are needed to guide these efforts. We aimed to describe the skin conditions seen by and management practices of Ghanaian dermatologists in a specialized clinic. Read More

PLoS Negl Trop Dis 2017 May 15;11(5):e0005607. Epub 2017 May 15.

Menzies School of Health Research, Charles Darwin University, Darwin, Australia.

Background: Strongyloides seroprevalence is hyper-endemic in many Australian Aboriginal and Torres Strait Islander communities, ranging from 35-60%. We report the impact on Strongyloides seroprevalence after two oral ivermectin mass drug administrations (MDAs) delivered 12 months apart in a remote Australian Aboriginal community.

Methods: Utilizing a before and after study design, we measured Strongyloides seroprevalence through population census with sequential MDAs at baseline and month 12. Read More

Psychiatr Danub 2017 May;29(Suppl 2):145-147

Department of Dermatology and Venereology, University Clinical Hospital Mostar, Kralja Tvrtka bb, 88000 Mostar, Bosnia and Herzegovina,

Aust Fam Physician 2017 ;46(5):264-268

Background: Scabies is a common, yet neglected, skin disease. Scabies occurs across Australia, but most frequently in socioeconomically disadvantaged populations in tropical regions, including in remote Aboriginal and Torres Strait Islander communities. In temperate settings, the disease clusters in institutional care facilities. Read More

Med Sante Trop 2017 May 4. Epub 2017 May 4.

Centre René Labusquière, Université de Bordeaux 3, Bordeaux, France.

Context: The meaning of the term "gale chinoise" mentioned in some articles about French overseas territories in the 19th century, remains unclear. In response to a query of an American colleague dermatologist trying to find out what it meant 150 years ago, we attempted to elucidate the nature of this ancient disease, which today would be translated literally as Chinese scabies.

Method: We submitted the query to a panel of civilian and military French tropical medicine specialists including dermatologists, through two networks : Association Amicale Santé Navale et d'Outre-Mer and Société de Pathologie Exotique. Read More

BMC Complement Altern Med 2017 May 2;17(1):241. Epub 2017 May 2.

Instituto de Biotecnología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Avenida Universidad S/N, Ciudad Universitaria, CP 66455, San Nicolás de los Garza, NL, Mexico.

Background: Thevetia peruviana (Pers.) K. Schum or Cascabela peruviana (L. Read More

Indian J Sex Transm Dis 2017 Jan-Jun;38(1):15-21

Department of Dermatology, Venereology, Leprosy, Government Medical College, Amritsar, Punjab, India.

Background: According to the World Health Organization criteria, geriatric population is people above 60 years of age. In this phase of life, a woman has already gone through menopause and its associated emotional, physical, and hormonal changes. These changes are due to gradual loss of estrogen that comes with menopause which results in dramatic changes in the appearance of vulva and vagina. Read More

J Clin Microbiol 2017 May;55(5):1599-1600

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.

J Clin Microbiol 2017 May;55(5):1233-1236

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.

JAAPA 2017 May;30(5):1-6

Judy Truscott is program director and an assistant professor in the PA program at Chatham University in Pittsburgh, Pa. Alyssa Abebe is an assistant professor at Chatham University and practices at an HIV research clinic at the University of Pittsburgh. Kelly Donkers is academic coordinator and an assistant professor in the PA program at Chatham University. Daria Segers is a senior PA with the University of Pittsburgh Physicians. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Parasitic infestations commonly are seen in patients in primary care, urgent care, and EDs. These infestations are a common cause of pruritus and may lead to secondary infestations. This article reviews the signs and symptoms of pinworms, lice, bedbug, and scabies infestations, as well as diagnosis and appropriate treatment. Read More

Cureus 2017 Mar 19;9(3):e1102. Epub 2017 Mar 19.

Department of Microbiology, Prathima Institute of Medical Sciences.

Scabies is a skin condition caused by infestation of the mite Sarcoptes scabiei. Sarcoptes scabiei var. hominis is an arthropod member belonging to the order Acarina. Read More

PLoS One 2017 19;12(4):e0176200. Epub 2017 Apr 19.

Norwegian Institute for Nature Research, Trondheim, Norway.

Sarcoptic mange is a widely distributed disease that affects numerous mammalian species. We used camera traps to investigate the apparent prevalence and spatiotemporal dynamics of sarcoptic mange in a red fox population in southeastern Norway. We monitored red foxes for five years using 305 camera traps distributed across an 18000 km2 area. Read More

Rheumatol Int 2017 Apr 18. Epub 2017 Apr 18.

Graduate Institute of Life Sciences, National Defense Medical Center, No. 161, Sec. 6, Minquan E. Road, Neihu District, Taipei, 114, Taiwan.

Scabies is a commonly occurring infectious immune-mediated inflammatory skin disease. Immune-mediated inflammatory processes are also observed in autoimmune diseases. There have been very few previous studies; however, that have investigated the possible association between scabies and autoimmune diseases. Read More

MMW Fortschr Med 2017 Apr;159(7):42-46

Universitätsklinikum Schleswig-Holstein, Campus Kiel, Dermatologie, Venerologie und Allergologie, Schmittenhelmstraße 7, D-24105, Kiel, Deutschland.

Ann Dermatol Venereol 2017 May 10;144(5):341-348. Epub 2017 Apr 10.

UMR 911, Inserm CRO2, « centre de recherche en oncologie biologique et oncopharmacologie », service de dermatologie, hôpital Timone, Aix-Marseille université, Assistance publique des Hôpitaux de Marseille, 13005 Marseille, France.

Background: Scabies has been on the rise in France in recent years and has posed therapeutic problems, mainly due to the withdrawal of benzyl benzoate. The objective of this study was to describe prescribing practices for scabies in children.

Methods: A national survey was conducted by means of a standardized questionnaire covering various clinical situations of scabies and the drugs used preferentially according to age, which was sent out between December 2014 and March 2015 to members of the clinical research group of the French Society of Paediatric Dermatology. Read More

Med Sante Trop 2017 Feb;27(1):90-94

Institut national d'hygiène publique (INHP), Abidjan Côte d'Ivoire.

Genital ulcers are among the seven syndromes of sexually transmitted infections (STIs) identified in Côte d'Ivoire. Ulcerative STIs present a public health problem because of their frequency and their role in the spread of HIV. Our objective was to investigate the epidemiological characteristics of genital ulcers observed in the STI center of the National Institute of Public Hygiene in Abidjan. Read More

Cutis 2017 Mar;99(3):202-204

University of Texas Medical Branch, Galveston, USA.

Crusted scabies is a severe, highly contagious form of classic scabies caused by the mite Sarcoptes scabiei var hominis. Crusted scabies is more common in immunosuppressed populations and overcrowded environments. In this condition, the host's immune system is overwhelmed and unable to defend against the mites on the skin, resulting in hyperinfestation of the host. Read More

Actas Dermosifiliogr 2017 Apr 3. Epub 2017 Apr 3.

Department of Dermatology, Hospital Universitario La Princesa, Spain.

Background: Oral ivermectin is an alternative therapy for human scabies infection due to its ease of administration and good safety profile. However, there is no definitive consensus on the optimal dosing regimen.

Objective: To describe the treatment of human scabies with different dosages of oral ivermectin and the possible adverse events. Read More

Ecohealth 2017 Jun 3;14(2):318-328. Epub 2017 Apr 3.

Regional Environmental Planning Inc, Tokyo, Japan.

We quantitatively evaluated the effects of landscape factors on the distribution of symptomatic raccoon dogs with sarcoptic mange along an urban gradient. We used 246 camera traps (182 traps from April 2005 to December 2006; 64 traps from September 2009 to October 2010) to record the occurrence of asymptomatic and symptomatic raccoon dogs at 21 survey sites along an urban-rural gradient in the Tama Hills area of Tokyo. Each occurrence was explained in terms of the surrounding forest, agricultural, and grassland areas and additional factors (i. Read More

Artif Cells Nanomed Biotechnol 2017 Apr 3:1-8. Epub 2017 Apr 3.

a Pharmaceutical Sciences Research Centre, Laboratory of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Nanjing Agricultural University , Nanjing , PR China.

To avoid potential systematical toxicity, solid lipid nanoparticles (SLNs) were prepared as a vehicle for transdermal delivery of ivermectin (IVM) using hot homogenisation followed by ultrasonic method. The as-prepared SLNs were approximately spherical shape with good stability. IVM was encapsulated in amorphous form within SLNs and displayed prolonged release from SLNs without burst release due to high encapsulation efficiency (EE). Read More

J Zoo Wildl Med 2017 Mar;48(1):265-268

A young adult, female, free-ranging Japanese raccoon dog ( Nyctereutes procyonoides viverrinus) with scabies infection was found dead as a result of traumatic injuries presumed to reflect vehicular trauma. Necropsy showed a large solid mass located on the left ovarian region, occupying a third of the abdominal cavity. Histologically, the mass contained complex tissues derived from three germinal layers, with areas of cuboidal or columnar epithelium, keratinized squamous epithelium, bone, cartilage, and adipose tissue. Read More

Zoonoses Public Health 2017 Mar 25. Epub 2017 Mar 25.

One Health Research Group, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Qld, Australia.

The objective of this review was to identify and critique over forty years of peer-reviewed literature concerned with the transmission of canine zoonoses to Aboriginal people and determine the zoonotic organisms documented in dogs in Australian Aboriginal communities. A systematic literature search of public health, medical and veterinary databases identified 19 articles suitable for critical appraisal. Thirteen articles documented the occurrence of recognized zoonotic organisms in dogs in Aboriginal communities, including Toxocara canis, Dirofilaria immitis, Streptococcus dysgalactiae, Rickettsia felis, Sarcoptes scabiei and Giardia. Read More

Ann Dermatol Venereol 2017 May 18;144(5):349-355. Epub 2017 Mar 18.

Service de dermatologie, hôpital Nord, chemin des Bourrely, 13015 Marseille, France.

Background: The infectious causes of cutaneous vasculitis are well known and include streptococcal infections among others. Cases resulting from parasitic infection are less frequent. Scabies, which is currently on the increase, has only been reported in a few isolated cases. Read More

PLoS Negl Trop Dis 2017 Mar 9;11(3):e0005437. Epub 2017 Mar 9.

QIMR Berghofer Medical Research Institute, Infectious Diseases Department, Herston, Brisbane, Australia.

Background: On a global scale scabies is one of the most common dermatological conditions, imposing a considerable economic burden on individuals, communities and health systems. There is substantial epidemiological evidence that in tropical regions scabies is often causing pyoderma and subsequently serious illness due to invasion by opportunistic bacteria. The health burden due to complicated scabies causing cellulitis, bacteraemia and sepsis, heart and kidney diseases in resource-poor communities is extreme. Read More

mSphere 2017 Mar-Apr;2(2). Epub 2017 Mar 1.

InBioS-Centre for Protein Engineering, University of Liège, Institut de Chimie, Liège, Belgium.

The acquisition of genetic material conferring the arsenal necessary for host virulence is a prerequisite on the path to becoming a plant pathogen. More subtle mutations are also required for the perception of cues signifying the presence of the target host and optimal conditions for colonization. The decision to activate the pathogenic lifestyle is not "taken lightly" and involves efficient systems monitoring environmental conditions. Read More

Australas J Dermatol 2017 Mar 1. Epub 2017 Mar 1.

Department of Parasitology and Mycology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.

Background/objectives: There is little data on the profile and magnitude of scabies in sub-Saharan African prisons. The present study aimed to assess the prevalence and determinants of scabies in prisons of the west region of Cameroon.

Methods: We conducted a cross-sectional study from March to August 2014, and consecutively recruited volunteer detainees of three randomly selected prisons in the West Region of Cameroon. Read More

JAMA Dermatol 2017 May;153(5):406-412

Institute for Health Metrics and Evaluation, University of Washington, Seattle.

Importance: Disability secondary to skin conditions is substantial worldwide. The Global Burden of Disease Study 2013 includes estimates of global morbidity and mortality due to skin diseases.

Objective: To measure the burden of skin diseases worldwide. Read More

Dermatol Pract Concept 2017 Jan 31;7(1):49-50. Epub 2017 Jan 31.

First Department of Dermatology, Aristotle University, Thessaloniki, Greece.

Dermoscopy is already considered a fairly established method for diagnosing scabies. This is because dermoscopy enables the visualization both of the burrow and the mite itself, forming the so-called "jet with a contrail" structure. In the present report we present an extraordinary case of a patient with scabies lesions on the face and neck, which was misdiagnosed during sequential visits and underwent unnecessary surgical diagnostic procedures. Read More

Transpl Infect Dis 2017 Jun 13;19(3). Epub 2017 Apr 13.

Department of Nephrology, Edouard Herriot Hospital Group, Lyon, France.

Vascularized composite tissue allografts include skin, which frequently undergoes, in the early post-graft period, acute rejections. The diagnosis of acute rejection may be difficult as it can be mimicked by several dermatoses. We present a bilateral hand allograft recipient who developed, 16. Read More

FP Essent 2017 Feb;453:26-32

University of North Carolina Chapel Hill School of Medicine Dermatology Residency Program, 410 Market St. Suite 400 CB#7715, Chapel Hill, NC 27516.

Skin infections account for a significant subset of dermatologic conditions of childhood. Common cutaneous viral infections in children include warts, molluscum contagiosum, hand-foot-and-mouth disease, and herpes simplex. Although viral infections are self-limited and often only mildly symptomatic, they can cause anxiety, embarrassment, and health care use. Read More

G Ital Dermatol Venereol 2017 Apr;152(2):192-193

Department of Dermatology, University of Maryland School of Medicine, Baltimore, MD, USA -

Med J Aust 2017 Feb;206(2):96

Menzies School of Health Research, Darwin, NT.

Exp Ther Med 2016 Dec 27;12(6):3711-3715. Epub 2016 Oct 27.

Department of General Medicine and Emergency Care, Toho University School of Medicine, Omori Hospital, Ota-ku, Tokyo 143-8541, Japan.

Scabies is an infection caused by Sarcoptes scabiei. In developed countries, scabies remains an important public health problem in hospitals and care facilities among elderly or immunocompromised patients. There are a number of medical providers who have not experienced scabies and there has been confusion surrounding its management and prevention. Read More

An Bras Dermatol 2016 Nov-Dec;91(6):826-828

Hospital do Câncer de Cascavel (Uopeccan) - Cascavel (PR), Brazil.

Human scabies affects all social classes and different races around the world. It is highly contagious, but the exact figures on its prevalence are unknown. A 19-year-old male patient was admitted to the emergency room reporting fever (38°C) and multiple lesions throughout the body, except face, soles, and palms. Read More

JAAPA 2017 Feb;30(2):1-3

At the time this article was written, Faye Mariz Razon was a student in the PA program at LSUHSC School of Allied Health. Emily Weidman-Evans is a clinical associate professor in the PA program at LSUHSC. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Scabies, an infectious disease caused by the scabies mite, manifests as an intensely pruritic skin rash. Children, the underprivileged, and patients with immunocompromise are at a higher risk of acquiring this contagious disease. Infectivity occurs worldwide in patients of all races, ages, and sex. Read More

Ann Dermatol Venereol 2017 May 4;144(5):356-361. Epub 2017 Jan 4.

Université François-Rabelais de Tours, 37000 Tours, France; Service de dermatologie, unité de dermatologie pédiatrique, CHRU de Tours, 37044 Tours cedex 9, France.

Background: There are no guidelines regarding the management of scabies in infants and recurrence is common at this age. We report the case of an infant with subungual hyperkeratosis and ungual lesions subsequent to classic scabies.

Patients And Methods: A 7-month-girl, treated 6 weeks earlier with esdepallethrin for scabies, consulted for acquired lesions on 3 toe nails. Read More