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Br J Dermatol 2019 Apr 20. Epub 2019 Apr 20.

Urgences pédiatriques, Centre Hospitalier Universitaire Hôpital pédiatrique Lenval, Nice, France.

Background: Expert visualization of Sarcoptes scabiei remains essential for diagnosing human scabies but access to experts can be difficult. PCR is a very specific tool for the detection and confirmation of Sarcoptes scabiei but this test has a poor sensitivity because of the requirement of previous expertise when collecting appropriate samples to gain a positive result.

Objective: Evaluate PCR as a diagnostic method for scabies using non expert-dependent standardized sampling. Read More

Pediatr Dermatol 2019 Apr 15. Epub 2019 Apr 15.

Division of Dermatology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California.

Bullous scabies is an uncommon subtype of scabies that frequently mimics other blistering skin diseases. Nocturnal pruritus is a hallmark symptom of bullous scabies. We report an unusual case of bullous scabies presenting in the absence of pruritus in an immunosuppressed pediatric patient. Read More

J Am Acad Dermatol 2019 05;80(5):e99-e100

Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China. Electronic address:

Am J Infect Control 2019 Apr 9. Epub 2019 Apr 9.

Columbia University, School of Nursing, New York, NY.

Background: Staff nurse and infection preventionist (IP) workload increases in response to exposures and outbreaks. Understanding the time burden associated with responding to specific pathogens may improve resource allocation. The purpose of this study was to evaluate workload increases reported by nurses and IPs in response to common exposures and outbreaks. Read More

J Dermatol 2019 Apr 10. Epub 2019 Apr 10.

Department of Dermatology, Shiga University of Medical Science, Otsu, Japan.

EC Microbiol 2019 Mar;15(3):160-167

Department of Parasitology, Universidad de Granada, Granada, Spain.

Introduction: Onchocerciasis, remains an unfamiliar condition for health professionals in Mozambique leading to its misdiagnosis as leprosy or scabies as noted in previous studies. Meta-analyses conducted in some African countries, have concluded that onchocerciasis is associated with epilepsy and nodding syndrome. Epilepsy affects at least 3% of the Mozambican population. Read More

Lancet Infect Dis 2019 Apr 4. Epub 2019 Apr 4.

St Johns Institute of Dermatology, Kings College London, London, UK.

Lancet Infect Dis 2019 Apr 4. Epub 2019 Apr 4.

Murdoch Children's Research Institute, Melbourne, VIC, Australia; Centre for International Child Health, University of Melbourne, Melbourne, VIC, Australia. Electronic address:

Background: In small community-based trials, mass drug administration of ivermectin has been shown to substantially decrease the prevalence of both scabies and secondary impetigo; however, their effect at large scale is untested. Additionally, combined mass administration of drugs for two or more neglected diseases has potential practical advantages, but efficacy of potential combinations should be confirmed.

Methods: The azithromycin ivermectin mass drug administration (AIM) trial was a prospective, single-arm, before-and-after, community intervention study to assess the efficacy of mass drug administration of ivermectin for scabies and impetigo, with coadministration of azithromycin for trachoma. Read More

Br J Dermatol 2019 Apr;180(4):710-711

Chelsea and Westminster NHS Foundation Trust, Chelsea, London, U.K.

Infect Control Hosp Epidemiol 2019 Mar 28:1-2. Epub 2019 Mar 28.

Pediatric Infectious Diseases, Department of Pediatrics,Emory University School of Medicine and Children's Healthcare of Atlanta,Atlanta, Georgia.

Clin Case Rep 2019 Mar 31;7(3):474-476. Epub 2019 Jan 31.

Department of Dermatology, Venereology and Allergology Medical University of Gdansk Gdansk Poland.

We present a rare case of crusted scabies in an human T-cell lymphotropic virus type 1 (HTLV-1) infected woman prior to onset of adult T-cell leukemia/lymphoma (ATL). We highlight the importance of this rare form of scabies as a prediagnostic sign of ATL, requiring high suspicion and monitoring of possible symptoms for early detection of ATL. Read More

Vet Dermatol 2019 Mar 21. Epub 2019 Mar 21.

Seoul Wildlife Center, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea.

Background: Sarcoptic mange in free-ranging raccoon dogs (Nyctereutes procyonoides) caused by Sarcoptes scabiei is a widespread zoonotic disease that causes severe skin lesions with significant morbidity and mortality. Fluralaner is a member of the isoxazoline chemical class and is an acaricide and insecticide widely used in flea, tick and mite infections of dogs (Canis lupus familiaris).

Objective: To evaluate the clinical efficacy of orally administered fluralaner in free-ranging raccoon dogs naturally infected with sarcoptic mange. Read More

Trop Med Infect Dis 2019 Mar 16;4(1). Epub 2019 Mar 16.

MD Dermatologist, Dipartimento di Medicina dei Servizi ASL Bari, Via Vico Traversa 11, 70127 Bari, Italy.

Scabies has always represented a diagnostic challenge for dermatologists, especially in subclinical cases or in atypical ones due to the coexistence of other diseases. Fortunately, dermatoscopy has enabled easier and faster in situ diagnosis. The aim of this study is to examine old and new dermatoscopic signs that produces on the skin during its whole life cycle through (dermatoscopy with an entomological focus) which, unlike traditional optical microscope examination, allows the local micro-environment to be preserved intact. Read More

Indian J Dermatol Venereol Leprol 2019 May-Jun;85(3):324-325

Department of Dermatology, Third People's Hospital of Hangzhou Affiliated to Zhejiang Chinese Medical University, Hangzhou, China.

Am J Infect Control 2019 Mar 15. Epub 2019 Mar 15.

First Division of Infectious Diseases, Cotugno Hospital, Napoli, Italy.

Clin Infect Dis 2019 Mar 15. Epub 2019 Mar 15.

Case Western Reserve University School of Medicine, Department of Dermatology, Cleveland, Ohio, U.S.A.

Background: Limited information exists regarding the burden of emergency department (ED) visits due to scabies in the United States (US). The goal of this study was to provide population-level estimates regarding scabies visits to American EDs.

Methods: This study was a retrospective analysis of the nationally representative National Emergency Department Sample from 2013-2015. Read More

Transpl Infect Dis 2019 Mar 15:e13077. Epub 2019 Mar 15.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

Crusted scabies is a rare disease variant associated with T-cell dysregulation. Transplant patients are at risk of developing crusted scabies as a consequence of their immunosuppressive regimens. We report a case of crusted scabies presenting with recurrent septicemia in a 65-year-old renal transplant recipient, treated with daily ivermectin for 7 days after initial failure of weekly ivermectin dosing. Read More

Parasit Vectors 2019 Mar 13;12(1):99. Epub 2019 Mar 13.

School of Biological Sciences, University of Tasmania, Sandy Bay, Hobart, Australia.

Background: Sarcoptic mange, caused by the Sarcoptes scabiei mite, is an infectious disease of wildlife, domestic animals and humans with international importance. Whilst a variety of treatment and control methods have been investigated in wildlife, the literature is fragmented and lacking consensus. The primary objectives of this review were to synthesise the diverse literature published on the treatment of sarcoptic mange in wildlife from around the world, and to identify the qualities of successful treatment strategies in both captive and free-roaming wildlife. Read More

J Pediatr 2019 Mar 7. Epub 2019 Mar 7.

The University of Texas Health Science Center, McGovern Medical School, Pediatric Infectious Diseases Division, Houston, Texas.

Arch Dis Child 2019 Mar 8. Epub 2019 Mar 8.

Division of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.

PLoS Negl Trop Dis 2019 03 8;13(3):e0007182. Epub 2019 Mar 8.

Centre for Health Economics Research and Evaluation, University of Technology Sydney, Sydney, Australia.

Background: Scabies is a common dermatological condition, affecting more than 130 million people at any time. To evaluate and/or predict the effectiveness and cost-effectiveness of scabies interventions, disease transmission modelling can be used.

Objective: To review published scabies models and data to inform the design of a comprehensive scabies transmission modelling framework to evaluate the cost-effectiveness of scabies interventions. Read More

Cleve Clin J Med 2019 Mar;86(3):163-164

Department of Dermatology, Mitoyo General Hospital, Kagawa, Japan.

BMC Infect Dis 2019 Feb 28;19(1):200. Epub 2019 Feb 28.

Department of Dermatology, University Hospital Basel, Petersgraben 4, 4056, Basel, Switzerland.

Background: Infestations with scabies mites are a global burden affecting individuals of all ages, classes and ethnicities. As poor sanitation and overcrowding favor the transmission of this highly contagious disease, epidemic outbreaks are frequently observed among displaced persons and asylum seekers. Due to the growing influx of refugees during the last years, public health authorities in host countries are frequently confronted with the challenge to treat individuals with diagnosed or suspected scabies promptly and effectively to avoid further spreading of the infestation. Read More

Rev Med Suisse 2019 Feb;15(640):466-472

Département vulnérabilités et médecine sociale, Centre universitaire de médecine générale et santé publique, 1011 Lausanne.

Our work develops procedures and useful tools for the screening, assessment and management of prevalent infectious or parasitic diseases (tuberculosis, measles, chickenpox, scabies, bed bugs) among asylum seekers and detainees in the canton of Vaud, populations living in similar closed settings. Its aim is to support health professionals in their work, to maintain the health of the target population and to protect the health of the community. Through a literature review and a focus group with experts, it is proposed to harmonize the existing procedures in asylum seekers centres end prisons of the canton of Vaud. Read More

Front Microbiol 2019 8;10:202. Epub 2019 Feb 8.

Department of Pharmaceutical Biology and Biotechnology, Institute of Pharmaceutical Sciences, University of Freiburg, Freiburg im Breisgau, Germany.

Potato common scab (PCS) is an economically important disease worldwide. In this study we demonstrated the possible role of AC12AB in controlling PCS. Isolates of were obtained from CS infected tubers collected from Maine United States, which were confirmed by morphological and molecular analysis including 16S rRNA sequencing and RFLP analysis of amplified 16S-23S ITS. Read More

Iran J Vet Res 2018 ;19(4):290-297

Department of Parasitology, Faculty of Veterinary Medicine, University of Belgrade, 11000 Beograd, Serbia.

A study was made on the prevalence of some parasitic infections appearing in domestic rabbits obtained from individual breeders in Serbia in order to improve the agricultural production of these animals. Aside from economic reasons (meat production and reproduction) rabbits are bred for the research purposes, and races are kept as household pets. For these reasons, among others, it is important to gain knowledge of medical culprits including causes of parasitic diseases that compromise their health, well-being and cause economic losses. Read More

Travel Med Infect Dis 2019 Feb 7. Epub 2019 Feb 7.

Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Dental Medicine, University of Zagreb, Zagreb, Croatia. Electronic address:

Nefrologia 2019 Feb 1. Epub 2019 Feb 1.

Dermatology Service of Hospital de Clínicas de Porto Alegre/Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.

PLoS Negl Trop Dis 2019 01 29;13(1):e0007111. Epub 2019 Jan 29.

Division of Emergency Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

Background: Despite the known burden of neglected tropical diseases (NTDs) on child health, there is limited information on current efforts to increase pediatric therapeutic options. Our objective was to quantify and characterize research activity and treatment availability for NTDs in children in order to inform the prioritization of future research efforts.

Methodology/principal Findings: We conducted a review of the World Health Organization's (WHO) International Clinical Trials Registry Platform to assess research activity for NTDs. Read More

J Drugs Dermatol 2019 01;18(1):105

I read with interest the excellent report by Tolkachjhov et al1 that describes the delay in diagnosis of a scabies infestation in a 90-year-old woman. Her condition mimicked dermatitis not only on clinical presentation but also on evaluation of skin biopsies. Read More

Dermatol Online J 2018 Aug 15;24(8). Epub 2018 Aug 15.

Division of Dermatology, Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, Ohio.

Nodular scabies is a hypersensitivity reaction to scabietic infestation characterized by persistent pruritic nodules that can remain even after treatment of the initial infestation. We present a demonstrative case of an infant who presented with nodular scabies. Read More

Dermatol Online J 2018 Sep 15;24(9). Epub 2018 Sep 15.

School of Medicine, University of California San Diego, La Jolla, California.

Scabies surrepticius is a unifying term that represents non-classical presentations of scabies mite infestation. A patient with scabies surrepticius is described: a man with scabies masquerading as prurigo nodularis. The 91-year-old man had metastatic prostate cancer and presented with diffuse pruritic nodules. Read More

J Am Acad Dermatol 2019 May 14;80(5):1435-1444. Epub 2019 Jan 14.

Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, New Lambton, Australia.

Background: Many drugs have been used to treat scabies, but it is unclear which of them is the most efficacious.

Objective: To evaluate the comparative efficacy and safety of antiscabietic agents.

Methods: A systematic review of randomized controlled trials was conducted. Read More

JAMA 2019 Feb;321(6):604-605

Department of Dermatology, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.

FP Essent 2019 Jan;476:18-24

University of South Dakota Sanford School of Medicine, 414 E. Clark Street, Vermillion, SD 57069.

Bedbugs, mites, and scabies are ectoparasites that commonly affect humans. Bedbugs ( species) were once rare in the United States but are now common. They cause intensely pruritic lesions on areas of exposed skin. Read More

Br J Dermatol 2019 Jan;180(1):e5

Odense Universitetshospital, Department of Dermatology and Allergy Centre, Odense, Region of Southern Denmark, Denmark.

J Family Med Prim Care 2018 Sep-Oct;7(5):1042-1046

Department of Dermatology, B S Medical College, Bankura, West Bengal, India.

Introduction: Prevalence of Sexually transmitted infections (STI's) in developing nations is very high where the measures for STI treatment and prevention are limited. Enormous variation in clinical presentation make STI's very difficult to be studied epidemiologically. To know the exact prevalence of STI's is very important for a region or community for planning preventive strategies. Read More

J Allergy Clin Immunol Pract 2019 Jan;7(1):28-33

Departments of Dermatology, Preventive Medicine and Medical Social Sciences, Feinberg School of Medicine at Northwestern University, Chicago, Ill; Northwestern Medicine Multidisciplinary Eczema Center, Chicago, Ill. Electronic address:

One in 4 adults with atopic dermatitis (AD) report adult-onset disease. Adult-onset AD appears to be associated with a different disease phenotype compared with childhood-onset AD. A broad differential diagnosis must be considered in a patient presenting with an adult-onset eczematous eruption, including allergic contact dermatitis, mycosis fungoides/cutaneous T-cell lymphoma, psoriasis, scabies, and so forth. Read More

Diseases 2018 Dec 29;7(1). Epub 2018 Dec 29.

Department of Family Medicine, Division of Medicine, Sengkang General Hospital, Singapore 544886, Singapore.

Scabies is a significant public health condition in long-term care facilities, plaguing even developed countries. Although treatments are available, eradication and control of scabies cases still remain a challenge due to delays in diagnosis and difficulties in maintaining preventive and surveillance measures. Prompt treatment of patients and their contacts that are affected, along with concomitant education of health staff and family members, are paramount. Read More

Br J Dermatol 2019 Apr 15;180(4):955. Epub 2019 Jan 15.

Department of Dermatology, Beaumont Hospital, Dublin 9, Ireland.

PLoS Negl Trop Dis 2018 12 27;12(12):e0006996. Epub 2018 Dec 27.

The Kirby Institute, University of New South Wales, Sydney, Australia.

Introduction: In most settings, the diagnosis of scabies is reliant on time-consuming and potentially intrusive clinical examination of all accesible regions of skin. With the recent recognition of scabies as a neglected tropical disease by the World Health Organization there is a need for standardised approaches to disease mapping to define populations likely to benefit from intervention, and to measure the impact of interventions. Development and validation of simplified approaches to diagnose scabies would facilitate these efforts. Read More

Trop Med Int Health 2019 Mar 28;24(3):280-293. Epub 2019 Jan 28.

Menzies School of Health Research, Charles Darwin University, Casuarina, Australia.

We conducted a systematic review of the treatment, prevention and public health control of skin infections including impetigo, scabies, crusted scabies and tinea in resource-limited settings where skin infections are endemic. The aim is to inform strategies, guidelines and research to improve skin health in populations that are inequitably affected by infections of the skin and the downstream consequences of these. The systematic review is reported according to the PRISMA statement. Read More

BMJ Case Rep 2018 Dec 3;11(1). Epub 2018 Dec 3.

Dermatology, Emek Medical Center, Afula, Israel.

Scabies is a pruritic disorder caused by Sarcoptes scabiei var. hominis infestation of the skin. Transferred by close body contact, scabies is endemic within nursing homes and among poor and overcrowded populations. Read More

Br J Clin Pharmacol 2019 Mar 24;85(3):626-633. Epub 2019 Jan 24.

Division of Clinical Pharmacology & Toxicology, University Hospital Basel, Switzerland.

Aims: The anthelminthic ivermectin is receiving new attention as it is being repurposed for new indications such as mass drug administrations for the treatment of scabies or in malaria vector control. As its pharmacokinetics are still poorly understood, we aimed to characterize the population pharmacokinetics of ivermectin in plasma and dried blood spots (DBS), a sampling method better suited to field trials, with special focus on the influence of body composition and enterohepatic circulation.

Methods: We performed a clinical trial in 12 healthy volunteers who each received a single oral dose of 12 mg ivermectin, and collected peripheral venous and capillary DBS samples. Read More

Dermatology 2019 13;235(2):79-90. Epub 2018 Dec 13.

International Foundation for Dermatology, London, United Kingdom.

Human scabies, a common infestation, has a worldwide distribution with a variable impact and presentation depending on the clinical situation. In developed, high-income settings, health institution and residential home outbreaks challenge health and social care services. In resource-poor settings, it is the downstream sequelae of staphylococcal and streptococcal bacteraemia, induced by scratching, which have a significant impact on the long-term health of communities. Read More

Infect Control Hosp Epidemiol 2019 Feb 7;40(2):261-263. Epub 2018 Dec 7.

1Collaborative Healthcare-Associated Infection Prevention Program,Dartmouth-Hitchcock Medical Center,Lebanon,New Hampshire.

J Ethnopharmacol 2019 Mar 6;232:55-61. Epub 2018 Dec 6.

Biomedical Research Center, Institute of Virology, Slovak Academy of Sciences, Dúbravská cesta 9, 845 05 Bratislava, Slovakia.

Ethnopharmacological Relevance: Essential oils and essential oil bearing medicinal and culinary plants have a long tradition of being used to combat infection, treat various conditions, and promote and restore health. Mint oils are traditionally applied to repel insects and treat various conditions including wounds, skin infections, inflammation, eczema, urticaria, psoriasis, scabies and insect bites. They are among essential oils promoted as a natural way to prevent tick-borne diseases and recommended as ingredients in various homemade repellent mixtures and tick-bite treatments. Read More

Am J Infect Control 2018 Dec 5. Epub 2018 Dec 5.

Division of Infectious Diseases, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.

Scabies is a re-emerging parasitic disease, particularly in hospitalized patients. This is a retrospective study analyzing adult patients with scabies admitted to a referral university hospital between 2008 and 2018. All patients were treated an average of 3 times using scabicides; the median isolation period and time to cure were 14 and 15 days, respectively. Read More

Lancet Infect Dis 2018 Dec;18(12):1310

Department of Dermatology, CHU Rennes, Rennes, France.

Lancet Infect Dis 2018 Dec;18(12):1309-1310

Office for Infection Control, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, South Korea; Department of Infectious Diseases, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, South Korea. Electronic address: