1,284 results match your criteria Saturday Review Drug Trials [Journal]
Am J Primatol 2018 Dec;80(12):e22933
Department of Animal Physiology, Institute for Zoology, University of Tübingen, Tübingen, Germany.
Diel activity rhythms in mammals are regulated by an endogenous (circadian) timing system which is synchronized by environmental 24-hr periodicities called zeitgebers. Additional direct responses to stochastic environmental factors ensure the fine-tuning to the actual situation and may mask the circadian time course. Following an observational study on behavioral effects of visitor activities in a group of spider monkeys (Ateles geoffroyi) kept free-ranging on a small island of Lake Catemaco, Veracruz, Mexico, we analyzed the effect of weekly varying numbers of visiting tourist boats on the monkeys' diel activity rhythm. Read More
Int J Drug Policy 2018 Nov 23;63:39-46. Epub 2018 Nov 23.
School of Psychology, Faculty of Health, Deakin University Geelong, Waterfront Campus, Locked Bag 20001, Geelong, VIC, 3220, Australia.
Background: This paper evaluates the impact of the AU$83 million introduction of 24-h public transport (PT) in Melbourne, Australia on Friday and Saturday nights on a sample of nightlife venues and venue patrons. This sample was selected because a primary reason for the introduction of 24 h PT was to provide a safe means of travel home for nightlife attendees.
Methods: Covert venue observations (pre-post) and a convenience sample of nightlife patron interviews (post-only) were conducted to measure the impact of 24-h PT on venues and venue patrons. Read More
Int J Surg Case Rep 2018 Nov 13;53:327-329. Epub 2018 Nov 13.
NHS Western Isles, Western Isles Hospital, Macaulay Road, Stonorway, HS12AF, United Kingdom. Electronic address:
Introduction: Epiploic appendagitis is a rare cause of acute abdominal pain. It's presentation often mimics other causes of acute abdominal pain. It is important for clinicians to be aware of an epiploic appendagitis since a delay in diagnosis can lead to unnecessary hospital stay, antibiotic usage and surgical intervention [1-4]). Read More
Appetite 2018 Nov 20;133:240-251. Epub 2018 Nov 20.
University of Otago, 23a Mein St, Newtown, 6242, Wellington, New Zealand. Electronic address:
Children's sugar-sweetened beverages (SSBs) consumption presents significant risks for obesity, type 2 diabetes and dental health. But there is a lack of objective data on beverages in children's overall environments. This study aimed to determine the nature and extent of children's beverage availability, purchase and consumption, throughout their day, using wearable cameras for data collection. Read More
Contraception 2018 Nov 19. Epub 2018 Nov 19.
University of Rochester Medical Center, 601 Elmwood Ave, Box 668, Rochester, NY 14642. Electronic address:
Objectives: To identify barriers to postpartum permanent contraception procedures after vaginal delivery and to explore contraceptive and reproductive outcomes of women who experience unfulfilled requests.
Study Design: We performed a retrospective cohort study of women requesting postpartum permanent contraception after vaginal delivery from 7/1/11 to 6/30/14 at Strong Memorial Hospital in Rochester, NY. We ascertained patient characteristics and outcomes through electronic medical records and birth certificate data search. Read More
Exp Clin Psychopharmacol 2018 Nov 1. Epub 2018 Nov 1.
Drinking heavily in a short period is associated with significant health risks. However, little is known about when heavy drinking occurs during an evening. Recently, research found that individuals increase their drinking pace across the evening, speeding up their drinking. Read More
Caries Res 2018 Sep 18;53(3):242-252. Epub 2018 Sep 18.
Center for Dental and Oral Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
This review assesses the development of oral health habits and status in European adults (35-44 years old) and senior citizens (65-74 years old) over the period of 1996-2016. There seem to be good opportunities for improving oral health habits by brushing twice daily with fluoride toothpaste among adults, as only 33-85% reported doing so. Caries experience was extensive among adults (≥92%). Read More
BMC Health Serv Res 2018 Sep 14;18(1):713. Epub 2018 Sep 14.
Eastern Health, Box Hill, Australia.
Background: Unplanned hospital readmissions are a quality and safety indicator. In Australian, 8% to 11.1% of unplanned readmissions occur ≤1 day of acute care discharge. Read More
Scand J Trauma Resusc Emerg Med 2018 Sep 10;26(1):74. Epub 2018 Sep 10.
Department of Anaesthesiology and Intensive Care Medicine, Hospital of the Brothers of St. John of God Salzburg, Teaching Hospital of the Paracelsus Medical University Salzburg, Salzburg, Austria.
Background: Lightning strikes are rare but potentially lethal. The risk for suffering a lightning strike in a mountain environment is unknown. The aim of this nationwide study was to analyse all lightning accidents in the Austrian Alps from 2005 to 2015, to assess the circumstances of the accident, the injury pattern as well as the outcome. Read More
PLoS One 2018 6;13(9):e0203586. Epub 2018 Sep 6.
Department of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Background: The aim of this study was to identify whether informal caregiving time is associated with personality factors longitudinally.
Methods: Longitudinal data were gathered from the German Socio-Economic Panel (GSOEP), a large nationally representative, longitudinal study of German households beginning in 1984. Focusing on the association between informal caregiving and personality factors, data were used from the years 2005, 2009 and 2013. Read More
Epilepsia Open 2018 Sep 4;3(3):364-373. Epub 2018 Jul 4.
Department of Neurology Albert Einstein College of Medicine and Montefiore Medical Center Bronx New York U.S.A.
Objective: To analyze data from Seizure Tracker, a large electronic seizure diary, including comparison of seizure characteristics among different etiologies, temporal patterns in seizure fluctuations, and specific triggers.
Methods: Zero-inflated negative binomial mixed-effects models were used to evaluate temporal patterns of seizure events (during the day or week), as well as group differences in monthly seizure frequency between children and adults and between etiologies. The association of long seizures with seizure triggers was evaluated using a mixed-effects logistic model with subject as the random effect. Read More
Rural Remote Health 2018 08 31;18(3):4730. Epub 2018 Aug 31.
Department of Dermatology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; and School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC
Introduction: Shortages and maldistribution of dermatology services have negative impacts on the quality of care for patients with skin problems. Only a limited amount of literature is available regarding the current state of dermatologic services in Taiwan. The aim of this study was to examine the urban-rural distribution of dermatologists and office-based dermatology services in Taiwan. Read More
Med Clin (Barc) 2018 Aug 23. Epub 2018 Aug 23.
Servicio de Medicina Interna, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
Internet Interv 2017 Sep 28;9:100-105. Epub 2017 Jul 28.
Schroeder Institute for Tobacco Research and Policy Studies at Truth Initiative, Washington, DC, USA.
Background: Previous analyses of Google search queries identified circaseptan (weekly) rhythms in smoking cessation information seeking, with Google searches for "quit" and "smoking" peaking early in the week. Similar patterns were observed for smoking cessation treatment seeking, such as calls to quitlines. These findings suggest that smoking cessation behaviors may have a weekly rhythm that could be leveraged to improve smoking cessation efforts. Read More
Int J Behav Med 2018 Oct;25(5):548-557
Faculty of Kinesiology, Sport, and Recreation, 1-141 University Hall, University of Alberta, 116 St & 85 Ave, Edmonton, AB, T6G 2R3, Canada.
Purpose: To examine associations between physical activity contexts and health and fitness perceptions among Korean adults and youth.
Method: Data were from the Korean Survey on Citizens' Sports Participation in 2015. Korean youth (N = 832; M = 14. Read More
PLoS Med 2018 Aug 13;15(8):e1002636. Epub 2018 Aug 13.
University of California, San Francisco, San Francisco, California, United States of America.
Background: In public health HIV treatment programs in Africa, long-term retention remains a challenge. A number of improvement strategies exist (e.g. Read More
J Infect Dis 2018 Nov;218(suppl_5):S409-S417
Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana.
Ebola virus (EBOV) and Marburg virus (MARV) outbreaks are highly lethal, and infection results in a hemorrhagic fever with complex etiology. These zoonotic viruses dysregulate the immune system to cause disease, in part by replicating within myeloid cells that would normally innately control viral infection and shape the adaptive immune response. We used triple knockout (TKO)-bone marrow, liver, thymus (BLT) humanized mice to recapitulate the early in vivo human immune response to filovirus infection. Read More
J Stud Alcohol Drugs 2018 Jul;79(4):644-648
Centre for Alcohol Policy Research, La Trobe University, Melbourne, Victoria, Australia.
Objective: Young people often drink more alcohol than intended over the course of a night. This study investigates individual and night-specific factors predicting young people's acknowledgment of having drunk more than intended.
Method: Using the Youth@Night smartphone application, 176 people aged 16-25 documented 757 Friday and Saturday nights. Read More
Can J Anaesth 2018 Dec 3;65(12):1303-1313. Epub 2018 Aug 3.
Interdepartment of Critical Care Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Purpose: Rapid response systems (RRSs) have been introduced into hospitals to help reduce the incidence of sudden cardiopulmonary arrest (CPA). This study evaluated whether an RRS reduces the incidence of in-hospital postoperative CPA.
Methods: This retrospective before-and-after analysis evaluated data collected from electronic medical records during a pre-intervention (January 2008 to September 2012) and post-intervention (implementation of an RRS) interval (October 2012 to December 2016) at a single tertiary care institution. Read More
Policy Brief UCLA Cent Health Policy Res 2017 08;2017(7):1-16
Parks after Dark is a Los Angeles County (County) program that began in 2010 as the primary prevention strategy of the County's Gang Violence Reduction Initiative. It has since evolved into a key County strategy to promote health, safety, equity, and community well-being. Led by the Department of Parks and Recreation (DPR), PAD is a collaboration of multiple County departments as well as community agencies. Read More
J Infect Dis 2018 Nov;218(suppl_5):S658-S661
Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana.
Antibody therapy has been used to treat a variety of diseases and the success of ZMapp and other monoclonal antibody-based therapies during the 2014-2016 West African Ebola outbreak has shown this countermeasure can be a successful therapy for Ebola hemorrhagic fever. This study utilized transchromosomal bovines (TcB) vaccinated with a DNA plasmid encoding Ebola virus glycoprotein sequence to produce human polyclonal antibodies directed against Ebola virus glycoprotein. When administered 1 day postinfection, these TcB polyclonal antibodies provided partial protection and resulted in a 50% survival rate following a lethal challenge of Ebola virus Makona in rhesus macaques. Read More
Crit Pathw Cardiol 2018 Sep;17(3):111-113
From the Montefiore Medical Center, Bronx, NY.
Background: The weekend effect is a phenomenon in which worse outcomes have been found to occur over the weekend. This has been investigated in the context of stroke, ST-elevation myocardial infarction, and pulmonary embolism among others. Atrial fibrillation (AF) is the most common sustained arrhythmia, and admissions for AF have been increasing. Read More
J Sleep Res 2018 Dec 23;27(6):e12737. Epub 2018 Jul 23.
Department of Communication Studies, University of Michigan, Ann Arbor, Michigan.
Shuteye latency (SEL) refers to the time spent performing activities in bed before attempting sleep. This study investigates (a) the prevalence, duration and predictors of SEL, (b) its association with insomnia symptoms (sleep onset latency [SOL], sleep quality and fatigue), and (c) the activities engaged in during SEL. A representative sample of 584 adults (18-96 years old) participated in an online survey. Read More
Dev Sci 2018 11 20;21(6):e12678. Epub 2018 Jul 20.
Institut des Sciences Cognitives Marc Jeannerod - UMR 5304, Centre National de la Recherche Scientifique (CNRS) and Université de Lyon, Lyon, France.
Older interlocutors are more likely than younger ones to make pragmatic inferences, that is, inferences that go beyond the linguistically encoded meaning of a sentence. Here we ask whether pragmatic development is associated with increased activity in brain structures associated with inference-making or in those associated with Theory of Mind. We employed a reading task that presents vignettes in one of two versions, one of which is expected to prompt more pragmatic processing. Read More
Clin Neurol Neurosurg 2018 Sep 9;172:160-161. Epub 2018 Jul 9.
Hans Berger Department of Neurology, Jena University Hospital, Jena, Germany. Electronic address:
We present a case of a patient with acute wrist drop caused by radial nerve torsion. NCS showed axonal lesion of the radial nerve. High-resolution ultrasound was able to visualize a constriction of the radial nerve. Read More
J Racial Ethn Health Disparities 2018 Jul 16. Epub 2018 Jul 16.
Department of Health Career Opportunity Programs, UConn Health, Schools of Medicine and Dental Medicine, Farmington, CT, 06030-3920, USA.
The Department of Health Career Opportunity Programs at UConn Health has developed the Aetna Health Professions Partnership Initiative (Aetna HPPI), a formal education consortium offering a comprehensive program of educational enrichment and support activities for underrepresented and first-generation students. The purpose is to identify and develop a diverse applicant pool of students who will eventually enter a health professions career with a focus on medicine and dental medicine. Activities are conducted for students in middle school through college. Read More
Br J Anaesth 2018 Jul 21;121(1):134-145. Epub 2018 May 21.
Leeds Teaching Hospitals NHS Trust, Leeds, UK; Manchester University NHS Foundation Trust, Manchester, UK (British Society of Allergy and Clinical Immunology); Manchester Academic Heath Science Centre, University of Manchester, Manchester, UK.
Background: UK national anaesthetic activity was studied in 2013 but weekend working was not examined. Understanding changes since 2013 in workload and manpower distribution, including weekends, would be of value in workforce planning.
Methods: We performed an observational survey of NHS hospitals' anaesthetic practice in October 2016 as part of the 6th National Audit Project of the Royal College of Anaesthetists (NAP6). Read More
J Physiother 2018 Jul 19;64(3):142-158. Epub 2018 Jun 19.
Allied Health Research Unit, Monash University, Melbourne, Australia.
Question: Are additional weekend allied health services effective and cost-effective for acute general medical and surgical wards, and subacute rehabilitation hospital wards?
Design: Systematic review and meta-analysis of studies published between January 2000 and May 2017. Two reviewers independently screened studies for inclusion, extracted data, and assessed methodological quality. Meta-analyses were conducted for relative measures of effect estimates. Read More
Ann R Coll Surg Engl 2018 Sep 18;100(7):551-555. Epub 2018 Jun 18.
Calderdale and Huddersfield NHS Foundation Trust , Huddersfield , UK.
Introduction The 'weekend effect' is said to occur when patient outcomes are adversely affected by the day of the week on which they present to hospital or have surgery. However, it is uncertain whether such a phenomenon exists for elective orthopaedic surgery. We investigated whether there is a 'weekend effect' in elective orthopaedic patients. Read More
J Natl Compr Canc Netw 2018 06;16(6):735-741
Department of Biomedical Data Sciences, Medical Decision Making, Leiden University Medical Center, Leiden; Dutch Institute for Clinical Auditing, Leiden; Department of Surgery, University Cancer Center Leiden|The Hague, The Hague; Department of Surgery, Reinier de Graaf Group, Delft; Department of Surgery, Leiden University Medical Center, Leiden; and Department of Surgical Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands.
It is unclear whether emergency weekend colon and rectal cancer surgery are associated with worse outcomes (ie, weekend effect) because previous studies mostly used administrative data, which may insufficiently adjust for case-mix. Prospectively collected data from the 2012-2015 Dutch ColoRectal Audit (n=5,224) was used to examine differences in 30-day mortality and severe complication and failure-to-rescue rates for emergency weekend (Saturday and Sunday) versus Monday surgery, stratified for colon and rectal cancer. Analyses were adjusted for age, sex, body mass index, Charlson comorbidity index, American Society of Anesthesiologists classification score, tumor stage, presence of metastasis, preoperative complication, additional resection for metastasis or locally advanced tumor, location primary colon tumor, type of rectal surgery (lower anterior resection or abdominal perineal resection), and type of neoadjuvant therapy (short-course radiotherapy or chemoradiotherapy). Read More
Ideggyogy Sz 2018 May;71(5-06):161-168
Department of Neurology, Semmelweis University, Budapest, Hungary.
Background And Purpose: The therapeutic time window of acute stroke is short. Decision on the use of intravenous thrombolysis is based on well-defined criteria. Any delay in the transport to a designated stroke centre decreases the odds of therapeutic success. Read More
Antiviral Res 2018 Aug 7;156:64-71. Epub 2018 Jun 7.
Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
The high case-fatality rate of confirmed MERS-CoV infections underlines the urgent need for an effective treatment to reduce the disease severity and mortality. REGN3051 and REGN3048 are two fully human neutralizing monoclonal antibodies (mAb) against MERS-CoV that reduced virus replication in mice expressing human DPP4 upon prophylactic and therapeutic treatment. Here, we evaluated the prophylactic and therapeutic efficacy of REGN3048 and REGN3051 in the common marmoset model of MERS-CoV infection. Read More
Emerg Infect Dis 2018 Sep 17;24(9):1696-1699. Epub 2018 Sep 17.
Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa fever is primarily supportive, although ribavirin has shown limited efficacy if administered early during infection. We tested favipiravir in Lassa virus-viremic macaques and found that 300 mg/kg daily for 2 weeks successfully treated infection. Read More
Ir J Med Sci 2018 Apr;187(Suppl 3):17-113
Chronobiol Int 2018 May;35(5):597-616
c Department of Biomedical Engineering , The University of Texas at Austin, Cockrell College of Engineering , Austin , Texas , USA.
Details of serious injuries to children ≤16 yrs. of age that necessitated urgent surgical intervention by the Department of Pediatric Surgery of the University Hospital of Lausanne, Switzerland were recorded into a database registry. Some 15 110 entries listed the precise time of injury, and 3114 (20. Read More
Addiction 2018 Oct 5;113(10):1862-1873. Epub 2018 Jul 5.
Clinical Institute of Occupational, Traffic and Sports Medicine, Ljubljana, Slovenia.
Background And Aims: Although generally prohibited by national regulations, underage gambling has become popular in Europe, with relevant cross-country prevalence variability. This study aimed to estimate the prevalence of underage gambling in Europe stratified by type of game and on-/off-line mode and to examine the association with individual and family characteristics and substance use.
Design: Our study used data from the 2015 European School Survey Project on Alcohol and Other Drugs (ESPAD) cross-sectional study, a survey using self-administered anonymous questionnaires. Read More
Age Ageing 2018 Sep;47(5):741-745
Department of Health Services Research & Policy, London School of Hygiene & Tropical Medicine, 15-17 Tavistock Place, London, UK.
Objective: to describe differences in care and 30-day mortality of patients admitted with hip fracture on weekends (Saturday-Sunday) compared to weekdays (Monday-Friday), and their relationship to the organisation of care.
Methods: data came from the National Hip Fracture Database (NHFD) linked to ONS mortality data on 52,599 patients presenting to 162 units in England between 1 January and 31 December 2014. This was combined with information on geriatrician staffing and major trauma centre (MTC) status. Read More
PLoS One 2018 24;13(5):e0198035. Epub 2018 May 24.
Department of General, Visceral and Transplant Surgery, University Hospital Münster, Münster, Germany.
Background: The weekend effect describes a phenomenon whereby patients admitted to hospitals on weekends are at higher risk of complications compared to those admitted during weekdays. However, if a weekend effect exists in orthotopic liver transplantation (oLT).
Methods: We analyzed oLT between 2006 and 2016 and stratified patients into weekday (Monday to Friday) and weekend (Saturday, Sunday) groups. Read More
J Intensive Care Med 2018 Jan 1:885066618778824. Epub 2018 Jan 1.
1 Pediatric department, Pediatric Intensive Care Unit, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Objective: To evaluate whether the off-hours admission has any effect on risk-adjusted mortality and length of stay for nonelective patients admitted to a pediatric intensive care unit (PICU) without 24-hour in-house intensivist coverage.
Design: Prospective cohort study.
Setting: A 34-bed tertiary PICU. Read More
PLoS One 2018 21;13(5):e0197494. Epub 2018 May 21.
Child Health, Royal Aberdeen Children's Hospital, Aberdeen, United Kingdom.
Mortality is higher for adults admitted to hospital and for babies born on weekends compared to weekdays. This study compares in-hospital mortality and in children admitted to hospital on weekends and weekdays. Details for all acute medical admissions to hospitals in Scotland for children aged ≤16 years between 1st January 2000 and 31st December 2013 were obtained. Read More
Clin Interv Aging 2018 9;13:895-901. Epub 2018 May 9.
Division of Community Medicine and Medical Education, Kobe University Graduate School of Medicine, Kobe, Japan.
Purpose: The aim of this study was to investigate whether the day of starting oral intake affects the clinical course of patients with aspiration pneumonia.
Results: We conducted a retrospective cohort study of 392 patients who were hospitalized for aspiration pneumonia but tolerated oral intake. Patients were divided into two groups according to the day of starting oral intake: Monday to Friday (midweek group) and Saturday or Sunday (weekend group). Read More
Epidemiol Prev 2018 Mar-Apr;42(2):192
Medico del lavoro.
J Forensic Leg Med 2018 Aug 8;58:78-81. Epub 2018 May 8.
Amsterdam Public Health Service Department of Forensic Medicine, The Netherlands. Electronic address:
We examined who, when, and where people non-fatally drowned of drowned in Amsterdam between January 2011 and December 2015 so that in the future more targeted and effective measures can be taken to prevent drowning. Data on non fatal drownings (N = 515, fire department database) were combined with the forensic medicine data on drowning fatalities (N=88). Who drowns in Amsterdam? The majority of those who drowned were men (82%). Read More
BMC Public Health 2018 Apr 20;18(1):530. Epub 2018 Apr 20.
Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Roessle-Strasse 10, 13125, Berlin, Germany.
Background: 24 h-accelerometry is now used to objectively assess physical activity (PA) in many observational studies like the German National Cohort; however, PA variability, observational time needed to estimate habitual PA, and reliability are unclear.
Methods: We assessed 24 h-PA of 50 participants using triaxial accelerometers (ActiGraph GT3X+) over 2 weeks. Variability of overall PA and different PA intensities (time in inactivity and in low intensity, moderate, vigorous, and very vigorous PA) between days of assessment or days of the week was quantified using linear mixed-effects and random effects models. Read More
J Obstet Gynaecol India 2018 Apr 9;68(2):148-150. Epub 2018 Jan 9.
Department of Obstetrics and Gynecology, Seth GS Medical College and KEM Hospital, Acharya Donde Marg, Parel, Mumbai, Maharashtra 400012 India.
JMIR Mhealth Uhealth 2018 Apr 16;6(4):e83. Epub 2018 Apr 16.
Johns Hopkins Weight Management Center, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.
Background: Although millions of overweight and obese adults use mobile phone apps for weight loss, little is known about the predictors of success.
Objective: The objective of this study was to understand the relationship between weight loss outcomes and weekly patterns of caloric intake among overweight and obese adults using a mobile phone app for weight loss.
Methods: We examined the relationship between weekly patterns of caloric intake and weight loss outcomes among adults who began using a weight loss app in January 2016 and continued consistent use for at least 5 months (N=7007). Read More
BMJ Open 2018 04 12;8(4):e016943. Epub 2018 Apr 12.
Centre for Primary Health Care and Equity, University of New South Wales, Sydney, New South Wales, Australia.
Objective: To examine the associations between day of week and time of admission and 30-day mortality for six clinical conditions: ischaemic and haemorrhagic stroke, acute myocardial infarction, pneumonia, chronic obstructive pulmonary disease and congestive heart failure.
Design: Retrospective population-based cohort analyses. Hospitalisation records were linked to emergency department and deaths data. Read More
Nat Microbiol 2018 May 9;3(5):556-562. Epub 2018 Apr 9.
Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Crimean-Congo haemorrhagic fever (CCHF) is the most medically significant tick-borne disease, being widespread in the Middle East, Asia, Africa and parts of Europe . Increasing case numbers, westerly movement and broadly ranging case fatality rates substantiate the concern of CCHF as a public health threat. Ixodid ticks of the genus Hyalomma are the vector for CCHF virus (CCHFV), an arbovirus in the genus Orthonairovirus of the family Nairoviridae. Read More