60,518 results match your criteria Salud Ciencia[Journal]


Physical activity less than the recommended amount may prevent the onset of major biological risk factors for cardiovascular disease: a cohort study of 198 919 adults.

Br J Sports Med 2018 Dec 15. Epub 2018 Dec 15.

IMDEA Food Institute, CEI UAM+CSIC, Madrid, Spain.

Objectives: We examined the dose-response relationship between physical activity (PA) and incidence of cardiovascular disease (CVD) risk factors in adults in Taiwan.

Methods: This study included 1 98 919 participants, aged 18-97 years, free of CVD, cancer and diabetes at baseline (1997-2013), who were followed until 2016. At baseline, participants were classified into five PA levels: inactive' (0 metabolic equivalent of task (MET)-h/week), 'lower insufficiently active' (0. Read More

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December 2018

A step towards development of promising trypanocidal agents: Synthesis, characterization and in vitro biological evaluation of ferrocenyl Mannich base-type derivatives.

Eur J Med Chem 2018 Dec 4;163:569-582. Epub 2018 Dec 4.

Dipartimento di Scienze e Innovazione Tecnologica, Università del Piemonte Orientale, Viale T. Michel 11, 15121, Alessandria, Italy. Electronic address:

Chagas disease is a neglected chronical parasitosis caused by the parasite Trypanosoma cruzi (T. cruzi). Nine ferrocenyl Mannich base derivatives were synthetized and characterized to explore their in vitro activity on three T. Read More

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December 2018

Genetic variability in the serotoninergic system and age of onset in anorexia nervosa and obsessive-compulsive disorder.

Psychiatry Res 2018 Dec 6;271:554-558. Epub 2018 Dec 6.

Department of Child and Adolescent Psychiatry and Psychology, Institute of Neurosciences, Hospital Clinic de Barcelona, C/ Villarroel 170, E-08036 Barcelona, Spain; Department of Medicine, University of Barcelona, Barcelona, Spain; The August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Carlos III Health Institute, Spain. Electronic address:

The age of onset of some psychiatric disorders may have etiopathogenic and clinical effects and may influence outcome. Following on from previous work by our group where we showed that early onset anorexia nervosa (AN) and obsessive-compulsive disorder (OCD) shared a common genetic background, the aim of the present study is to assess genetic pleiotropy related to the serotonergic system (SLC6A4, 5HTR2A, 5HTR2C, TPH2, SLC18A1), in a common phenotype such as very-early age of onset. One hundred and sixteen adolescents diagnosed with AN and 74 adolescents diagnosed with OCD participated in the present study. Read More

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December 2018

Psychobiological response to an anger induction task in schizophrenia: The key role of anxiety.

Psychiatry Res 2018 Dec 7;271:541-547. Epub 2018 Dec 7.

Unitat de Psiquiatria i Psicologia Mèdica, Facultat de Medicina, Universitat de València, Avda. Blasco Ibáñez 15, València E. 46010, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM); Hospital Clínico Universitario de Valencia . Instituto de Investigación Sanitaria (INCLIVA).

In this study an anger induction laboratory task was applied to men with schizophrenia, and resulted in significant changes in different psychophysiological parameters that were measured in a pre-post design. We observed a significantly greater self-reported anger mood and negative affection, lower self-reported positive affection, an increase in cardiovascular reactivity (with blood pressure in deeper affection compared to controls), higher salivary testosterone levels, lower salivary cortisol levels, and an increase in right ear items reported in dichotic listening. Furthermore, clinical risk factors related to anger in our patients were analyzed by Stepwise Regression analyses. Read More

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December 2018

Association between prenatal opioid exposure, neonatal opioid withdrawal syndrome, and neurodevelopmental and behavioral outcomes at 5-8 months of age.

Early Hum Dev 2018 Dec 13;128:69-76. Epub 2018 Dec 13.

Department of Family and Community Medicine, School of Medicine, University of New Mexico, Albuquerque, NM, United States of America.

Background: While use of prescription opioids and medication assisted therapy (MAT) for opioid use disorder in pregnancy, as well as the incidence of neonatal opioid withdrawal syndrome (NOWS) continue to rise, little is known about outcomes for children with NOWS beyond the newborn period.

Methods: We examined 1) prenatal MAT exposure vs. unexposed healthy controls [HC]; and 2) treatment for NOWS and NOWS severity on infant neurodevelopmental and behavioral outcomes at 5-8 months of age in 78 maternal-infant pairs from the ENRICH prospective cohort study. Read More

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December 2018

Design Strategies for Shape-Controlled Magnetic Iron Oxide Nanoparticles.

Adv Drug Deliv Rev 2018 Dec 13. Epub 2018 Dec 13.

Dept. Energía, Medio Ambiente y Salud, Instituto de Ciencia de Materiales de Madrid, CSIC, Cantoblanco, E-28049, Madrid, Spain. Electronic address:

Ferrimagnetic iron oxide nanoparticles (magnetite or maghemite) have been the subject of an intense research, not only for fundamental research but also for their potentiality in a widespread number of practical applications. Most of these studies were focused on nanoparticles with spherical morphology but recently there is an emerging interest on anisometric nanoparticles. This review is focused on the synthesis routes for the production of uniform anisometric magnetite/maghemite nanoparticles with different morphologies like cubes, rods, disks, flowers and many others, such as hollow spheres, worms, stars or tetrapods. Read More

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December 2018

Interhospital Variability in Acute Coronary Syndrome Management in the ATHOS Study.

Rev Esp Cardiol (Engl Ed) 2018 Dec 12. Epub 2018 Dec 12.

Grupo REGICOR, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Barcelona, Spain; CIBERCV de Enfermedades Cardiovasculares, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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December 2018

Late onset distal myopathy: A new telethoninopathy.

Neuromuscul Disord 2018 Nov 13. Epub 2018 Nov 13.

Unidad de Neuromuscular, Hospital Universitario 12 de Octubre, Instituto i+12 y U-723 del CIBERER, Spain.

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November 2018

Descriptive epidemiology of Yersinia enterocolitica infection in a high-incidence area over an 8-year period, 2006-2013. EDICS project.

Enferm Infecc Microbiol Clin 2018 Dec 12. Epub 2018 Dec 12.

Sección Epidemiología, Centro Salud Pública, Castelló, España; CIBER-ESP grupo 41; Departamento de Medicina, Facultad de Ciencias de la Salud, Universitat Jaume I (UJI), España. Electronic address:

Descriptive epidemiology of Yersinia enterocolitica infection in an area of Castellón (Spain) between 2006 and 2013 from Yersinia enterocolitica strains isolated in the area and confirmed by the Spanish national reference laboratory. There were a total of 144 cases. The estimated incidence was 9. Read More

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December 2018

Mediterranean diet and knee osteoarthritis outcomes: A longitudinal cohort study.

Clin Nutr 2018 Dec 4. Epub 2018 Dec 4.

National Research Council, Neuroscience Institute, Aging Branch, Padova, Italy.

Objectives: Mediterranean diet has several beneficial effects on health, but data regarding the association between Mediterranean diet and knee osteoarthritis (OA) are limited mainly to cross-sectional studies. We investigated whether higher Mediterranean diet adherence is prospectively associated with lower risk of radiographic OA (ROA), radiographic symptomatic knee OA (SxOA) and pain worsening in North American people at high risk or having knee OA.

Methods: Adherence to the Mediterranean diet was evaluated using a validated Mediterranean diet score (aMED), categorized in five categories (Q1 to Q5, higher values reflecting higher adherence to Mediterranean diet). Read More

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December 2018

Muscle loss: The new malnutrition challenge in clinical practice.

Clin Nutr 2018 Nov 30. Epub 2018 Nov 30.

Servicio de Geriatría, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain. Electronic address:

Recent definitions of malnutrition include low muscle mass within its diagnostic criteria. In fact, malnutrition is one of the main risk factors of skeletal muscle loss contributing to the onset of sarcopenia. However, differences in the screening and diagnosis of skeletal muscle loss, especially as a result of malnutrition in clinical and community settings, still occur mainly as techniques and thresholds used vary in clinical practice. Read More

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November 2018

Alkylphenolic compounds and risk of breast and prostate cancer in the MCC-Spain study.

Environ Int 2018 Dec 12. Epub 2018 Dec 12.

Unit of Molecular Epidemiology and Genetics in Infections and Cancer, IDIBELL, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Barcelona, Spain. Electronic address:

Background: Alkylphenolic compounds are chemicals with endocrine disrupting properties that have been widely used in industry with important changes in their usage over time. Few epidemiologic studies have evaluated the effect of alkylphenolic compounds on human health.

Objectives: We investigated whether occupational exposure to alkylphenolic compounds is associated with breast and prostate cancer. Read More

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December 2018

[Health in all policies in the Valencian Community: steps towards the health impact assessment].

Gac Sanit 2018 Dec 12. Epub 2018 Dec 12.

Dirección General de Salud Pública, Conselleria de Sanitat Universal i Salut Pública, Valencia, España.

This paper describes the beginning of the implementation process of the health impact assessment in the Valencian Community (Spain), as an instrument to incorporate the framework of social determinants and health inequalities in the policies issued by the different departments of the Valencian government. The proposal involves: 1) political commitment, with legislative and strategic planning actions; 2) the creation of structures to allow intersectoral collaboration, with the establishment of the health impact assessment commission and the intersectoral technical committee; and 3) the design and validation of a tool for the simplified health impact assessment of non-health policies adapted to the Valencian Community. We highlight the importance of the participatory methodology used in the whole process and the potential of the health impact assessment for the development of public policies oriented to improve health and equity. Read More

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December 2018

Evaluation of a multidisciplinary training program in magnetic resonance imaging of patients with axial spondyloarthritis: PROGRESSES Project.

Radiologia 2018 Dec 12. Epub 2018 Dec 12.

Unidad de Radiodiagnóstico, Hospital Universitario Fundación Alcorcón, Madrid, España.

Objective: To analyze the impact of a multidisciplinary training program in magnetic resonance imaging (MRI) for axial spondyloarthritis in daily clinical practice.

Methods: After two years of training workshops for radiologists and rheumatologists, we designed a survey to assess changes in: 1) communication and collaboration between departments; 2) radiologists' interest and keeping up to date in axial spondyloarthritis and rheumatologists' training in MRI; 3) number of MRI studies done; 4) availability of protocols about technical requirements for studying axial spondyloarthritis by MRI and of standardized reporting templates; 5) evaluation and management of axial spondyloarthritis; 6) areas of improvement.

Results: After 50 workshops, 96 rheumatologists and 51 radiologists completed the survey. Read More

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December 2018

One-carbon metabolism nutrient intake and the association between body mass index and urinary arsenic metabolites in adults in the Chihuahua cohort.

Environ Int 2018 Dec 12;123:292-300. Epub 2018 Dec 12.

Environmental Science and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Curriculum in Toxicology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address:

Background: Exposure to inorganic arsenic (iAs) via drinking water is a serious global health threat. Various factors influence susceptibility to iAs-associated health outcomes, including differences in iAs metabolism. Previous studies have shown that obesity is associated with iAs metabolism. Read More

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December 2018
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Mechanisms of Pyrethroid Resistance in Aedes (Stegomyia) aegypti from Colombia.

Acta Trop 2018 Dec 12. Epub 2018 Dec 12.

Centro Internacional de Entrenamiento e Investigaciones Médicas CIDEIM, Carrera 125 N 19-225, Cali, Colombia; Universidad ICESI, Cali,Colombia. Electronic address:

In Colombia Aedes (Stegomyia) aegypti is the main vector of urban arboviruses such as dengue, chikungunya and Zika. This urban mosquito has a well-established capacity to develop insecticide resistance to different types of insecticides (pyrethroids, organochlorides, organophosphates), using multiple resistance mechanisms. An understanding of ongoing resistance mechanisms is critical to determining the activities of vector control programs. Read More

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December 2018

WPA Position Statement on Spirituality and Religion in Psychiatry.

Actas Esp Psiquiatr 2018 Nov 1;46(6):242-8. Epub 2018 Nov 1.

WPA Sección Sobre Religión, Espiritualidad y Psiquiatría Departamento de Teología y Religión, Universidad de Durham, Durham, UK.

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November 2018

Factors predicting early dropout from dialectical behaviour therapy in individuals with borderline personality disorder.

Actas Esp Psiquiatr 2018 Nov 1;46(6):226-33. Epub 2018 Nov 1.

Department of Psychiatry, Hospital de la Santa Creu i Sant Pau, Barcelona (Spain) Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona (UAB), Barcelona (Spain) Institut d'Investigació Biomèdica- Sant Pau (IIB-SANT PAU), Barcelona (Spain) Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM (Spain).

Background: Dialectical behaviour therapy skills training (DBT-ST) has proven effective to treat individuals with borderline personality disorder (BPD). However, therapy still faces the problem of early dropout. The aim of the present study is to examine which factors are associated with early dropout from DBT-ST in a sample of subjects with BPD. Read More

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November 2018

Sexual dysfunction factors in patients with schizophrenia treated with second generation antipsychotics: not only prolactin.

Actas Esp Psiquiatr 2018 Nov 1;46(6):217-25. Epub 2018 Nov 1.

Unidad de Gestión Clínica de Salud Mental. Hospital Universitario de Valme. Sevilla. España.

Introduction: Despite the high prevalence of sexual dysfunction in patients with schizophrenia, its origins are still unclear.

The Aim Of This Study: to determine the prevalence and causal factors of sexual dysfunction in a group of outpatients with schizophrenia.

Methods: The study was designed to be cross-sectional and naturalistic, including outpatients with schizophrenia undergoing second generation antipsychotic monotherapy. Read More

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November 2018

Alternative transcript imbalance underlying breast cancer susceptibility in a family carrying PALB2 c.3201+5G>T.

Breast Cancer Res Treat 2018 Dec 14. Epub 2018 Dec 14.

Oncogenetics Group, Vall d'Hebron Institute of Oncology, VHIO, 08035, Barcelona, Spain.

Purpose: Disruption of splicing motifs by genetic variants can affect the correct generation of mature mRNA molecules leading to aberrant transcripts. In some cases, variants may alter the physiological transcription profile composed of several transcripts, and an accurate in vitro evaluation is crucial to establish their pathogenicity. In this study, we have characterized a novel PALB2 variant c. Read More

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December 2018

Growth plate alterations in chronic kidney disease.

Pediatr Nephrol 2018 Dec 14. Epub 2018 Dec 14.

Division of Pediatrics, Department of Medicine, Faculty of Medicine, University of Oviedo, CP 33006, Oviedo, Asturias, Spain.

Growth retardation is a major feature of chronic kidney disease (CKD) of onset in infants or children and is associated with increased morbidity and mortality. Several factors have been shown to play a causal role in the growth impairment of CKD. All these factors interfere with growth by disturbing the normal physiology of the growth plate of long bones. Read More

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December 2018
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Publisher Correction: Obestatin controls skeletal muscle fiber-type determination.

Sci Rep 2018 Dec 14;8(1):17978. Epub 2018 Dec 14.

Área de Endocrinología Celular y Molecular, Instituto de Investigación Sanitaria de Santiago (IDIS), Complejo Hospitalario Universitario de Santiago (CHUS), Servicio Gallego de Salud (SERGAS), Santiago de Compostela, Spain.

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. Read More

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December 2018

Serum alkaline phosphatase relates to cardiovascular risk markers in children with high calcium-phosphorus product.

Sci Rep 2018 Dec 14;8(1):17864. Epub 2018 Dec 14.

Pediatric Endocrinology group, (Girona Biomedical Research Institute) IDIBGI, Girona, Spain.

Although alkaline phosphatase (ALP) correlates with cardiovascular risk in adults, there are no studies in children. We evaluated the association between serum ALP levels, calcium-phosphorus product (Ca*P) and cardiovascular risk markers in healthy children. Children aged 7. Read More

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December 2018
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Cost of oropharyngeal dysphagia after stroke: protocol for a systematic review.

BMJ Open 2018 Dec 14;8(12):e022775. Epub 2018 Dec 14.

Centro de Investigación Biomédica en Red de enfermedades hepáticas y digestivas (CIBERehd), Instituto de Salud Carlos III, Barcelona, Spain.

Introduction: Oropharyngeal dysphagia (OD) is a major disorder following stroke. OD can produce alterations in both the efficacy and safety of deglutition and may result in malnutrition, dehydration, frailty, respiratory infections and pneumonia. These complications can be avoided by early detection and treatment of OD in poststroke patients, and hospital stays, medication and mortality rates can be reduced. Read More

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December 2018

Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis.

Ann Rheum Dis 2018 Dec 14. Epub 2018 Dec 14.

Rheumatology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain

Objective: Psoriatic arthritis (PsA) is a chronic inflammatory arthritis affecting up to 30% of patients with psoriasis (Ps). To date, most of the known risk loci for PsA are shared with Ps, and identifying disease-specific variation has proven very challenging. The objective of the present study was to identify genetic variation specific for PsA. Read More

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December 2018

Postdischarge Mortality Prediction in Sub-Saharan Africa.

Pediatrics 2018 Dec 14. Epub 2018 Dec 14.

Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique;

Background: Although the burden of postdischarge mortality (PDM) in low-income settings appears to be significant, no clear recommendations have been proposed in relation to follow-up care after hospitalization. We aimed to determine the burden of pediatric PDM and develop predictive models to identify children who are at risk for dying after discharge.

Methods: Deaths after hospital discharge among children aged <15 years in the last 17 years were reviewed in an area under demographic and morbidity surveillance in Southern Mozambique. Read More

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December 2018

Safety of Peripherally Inserted Central Catheter Use in Children From Rural Versus Urban Settings Receiving Long-term Parenteral Antimicrobial Therapy.

Hosp Pediatr 2018 Dec 14. Epub 2018 Dec 14.

Division of Infectious Diseases, Department of Pediatrics, and

Objectives: To determine the safety of peripherally inserted central catheter (PICC) use for delivery of outpatient parenteral antimicrobial therapy (PAT) in children discharged to rural or urban locales. We hypothesized that children from rural settings would experience higher complication rates.

Patients And Methods: We conducted a retrospective cohort study of children admitted to an academic medical center in the Southwestern United States over 9 years who were discharged with a PICC to complete a course of PAT with follow-up at our institution. Read More

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December 2018

Is hepatitis A virus infection under control? lessons in the application of viral sequencing for the development of vaccination schemes in emergency situations.

Authors:
Nora A Fierro

EBioMedicine 2018 Dec 11. Epub 2018 Dec 11.

Unidad de Inmunovirologia, Servicio de Biologia Molecular en Medicina, Hospital Civil de Guadalajara ″Fray Antonio Alcalde″, Mexico; Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico. Electronic address:

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December 2018

[Malaria in an immigrant patient traveling back to his country].

Semergen 2018 Dec 11. Epub 2018 Dec 11.

Medicina Familiar y Comunitaria, Centro de Salud Panaderas, Fuenlabrada, Madrid, España.

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December 2018

[Central serous chorioretinopathy secondary to Helicobacter pylori: To treat or not to treat, that is the question].

Semergen 2018 Dec 11. Epub 2018 Dec 11.

Grupo EpiChron de Investigación en Enfermedades Crónicas, Instituto Aragonés de Ciencias de la Salud (IACS), ISS Aragón, Zaragoza, España; Centro de Salud Delicias Sur, Zaragoza, España.

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December 2018

Psychosis as debut of sporadic Creutzfeldt-Jakob disease.

Rev Psiquiatr Salud Ment 2018 Dec 11. Epub 2018 Dec 11.

Servicio Neurología, Clinical Neuroscience Research, IRBLleida-Hospital Universitari Arnau Vilanova, Lleida, España; Unitat Trastorns Cognitius, Clinical Neuroscience Research, IRBLleida-Hospital Universitari Santa Maria, Lleida, España. Electronic address:

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December 2018

[Molecular epidemiology of carbapenem-resistant isolates of Acinetobacter baumannii in Argentina].

Rev Argent Microbiol 2018 Dec 11. Epub 2018 Dec 11.

Laboratorio de Bacteriología, Departamento de Bioquímica Clínica, Hospital de Clínicas José de San Martín, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, INFIBIOC, UBA, Buenos Aires, Argentina.

One hundred sequential, epidemiologically unrelated carbapenem-resistant- Acinetobacter baumannii isolates from 11 hospitals in 10 Argentine provinces were collected between January and August 2016. Genes coding for Ambler class D and B carbapenemases were investigated by PCR using specific primers. All isolates were typed using the 3-locus sequence typing and blalike sequence-based typing techniques. Read More

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December 2018

Do avian malaria parasites reduce vector longevity?

Curr Opin Insect Sci 2018 Aug 25;28:113-117. Epub 2018 Aug 25.

Estación Biológica de Doñana (EBD-CSIC), Calle Américo Vespucio, 26, E-41092 Seville, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Seville, Spain.

Avian Plasmodium and malaria-like parasites of the genus Haemoproteus are widespread vector-borne parasites commonly found infecting birds. These parasites impose deleterious effects on their vertebrate hosts compromising their survival. While the interaction between these parasites and their vertebrate hosts has received much attention, the study of those factors determining the consequences of parasite infections in the insect vectors has been traditionally neglected. Read More

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Bread Consumption Is Associated with Elevated Blood Pressure among Adults Living in Mexico City⁻A Sub-Analysis of the Tlalpan 2020 Study.

Nutrients 2018 Dec 13;10(12). Epub 2018 Dec 13.

Division of Research, National Institute of Cardiology Ignacio Chávez, Mexico City 14080, Mexico.

Excessive dietary sodium is associated with elevated blood pressure (EBP). Bread products are identified as one of the main sources of daily sodium intake. The objective of this cross-sectional study was to evaluate the association between bread and others cereal products consumption with EBP. Read More

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December 2018

Beyond diagnosis: Mentalization and mental health from a transdiagnostic point of view in adolescents from non-clinical population.

Psychiatry Res 2018 Dec 21;270:755-763. Epub 2018 Oct 21.

Department of Clinical and Health Psychology, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain; Department of Mental Health. Fundació Sanitària Sant Pere Claver, Barcelona, Catalonia, Spain; Centre for Biomedical Research Network on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.

An increasing volume of evidence suggests that mentalization (MZ) can be an important factor in the transition from mental health to mental illness and vice versa. However, most studies are focused on the role of MZ in specific disorders. This study aims to evaluate the relationship between MZ and mental health as a trans-diagnostic process. Read More

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December 2018

Targeting STATs in neuroinflammation: the Road Less Traveled!

Pharmacol Res 2018 Dec 11. Epub 2018 Dec 11.

Department of Pharmacology, Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran.

JAK/STAT transduction pathway is a highly conserved pathway implicated in regulating cellular proliferation, differentiation, survival and apoptosis. Dysregulation of this pathway is involved in the onset of autoimmune, haematological, oncological, metabolic and neurological diseases. Over the last few years, the research of anti-neuroinflammatory agents has gained considerable attention. Read More

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December 2018
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Neonatal exposure to a glyphosate-based herbicide alters the histofunctional differentiation of the ovaries and uterus in lambs.

Mol Cell Endocrinol 2018 Dec 11. Epub 2018 Dec 11.

Instituto de Salud y Ambiente del Litoral (ISAL), Facultad de Bioquímica y Ciencias Biológicas, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional del Litoral, Santa Fe, Argentina. Electronic address:

The aim of the present study was to compare the effect of oral and subcutaneous exposure to a glyphosate-based herbicide (GBH) on the female reproductive system, specifically in the ovaries and uterus of prepubertal lambs. To this end, ewe lambs were exposed to a s.c. Read More

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December 2018

Mortality of patients with chronic disease: an increasing problem.

J Pediatr (Rio J) 2018 Dec 11. Epub 2018 Dec 11.

Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria, Pediatric Intensive Care Unit, Madrid, Spain; Maternal and Child Health and Development Network, RETICS funded by the PN I+D+I 2013-2016 (Spain), ISCIII-Sub-Directorate General for Research Assessment and Promotion and the European Regional Development Fund (ERDF), Spain; Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Salud Pública y Maternoinfantil, Madrid, Spain. Electronic address:

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December 2018
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Interventions to treat cutaneous leishmaniasis in children: A systematic review.

PLoS Negl Trop Dis 2018 Dec 14;12(12):e0006986. Epub 2018 Dec 14.

Unidad Clínica de Leishmaniasis, Centro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia.

Background: Case management in children with cutaneous leishmaniasis (CL) is mainly based on studies performed in adults. We aimed to determine the efficacy and harms of interventions to treat CL in children.

Methods: We conducted a systematic review of clinical trials and cohort studies, assessing treatments of CL in children (≤12 years old). Read More

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December 2018
2 Reads

[Jesús Kumate 1924-2018].

Authors:
Jaime Sepúlveda

Salud Publica Mex 2018 Sep-Oct;60(5):605-608

Director Ejecutivo. UCSF Institute for Global Health Sciences. Discurso pronunciado en el Instituto Nacional de Salud Pública; 22 de mayo de 2018.

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December 2018

[New tobacco products, a threat for tobacco control and public health of Mexico].

Salud Publica Mex 2018 Sep-Oct;60(5):598-604

Departamento de Investigación sobre Tabaco, Instituto Nacional de Salud Pública. Cuernavaca, Morelos. México.

The new tobacco products that include electronic cigarettes (called "E Cig", "e-hookahs", "mods", "vape-pens"), electronic nicotine delivery systems (SEAN, Spanish acronym), similar systems without nicotine (SSSN, Spanish acronym) and alternative nicotine consumption systems (SACN, Spanish acronym), are positioned in the global market with a discourse of harm reduction and risk minimization. This manuscript summarizes the scientific evidence and presents a regulatory proposal for this technological innovation, oriented to guide the decision making of legislators, government institutions and organized civil society. The scientific evidence concludes that there is no safe tobacco product for health. Read More

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August 2017
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[Position of the Latin American Society of Nutrition (SLAN) on the management of conflict of interest.]

Salud Publica Mex 2018 Sep-Oct;60(5):592-597

Centro de Investigación en Nutrición y Salud, Instituto Nacional de Salud Pública. Cuernavaca, México.

There is solid evidence documenting relationships between the food and beverage industry and academia that shows that industry sponsored research is likely to bias results in favor of industry. In Latin America, examples of these situations have been documented in Mexico, Brazil, Chile, Peru, Colombia, and Ecuador, among others. Due to the urgent need for studying and managing relationships between the food and beverage industry and the field of health and nutrition research, in 2017, the President of the Latin American Society of Nutrition (SLAN) appointed a Conflict of Interest Committee (CCI). Read More

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[Position paper on taxes to non-basic energy-dense foods and sugar-sweetened beverages].

Salud Publica Mex 2018 Sep-Oct;60(5):586-591

Dirección General, Instituto Nacional de Salud Pública. México.

In 2014 the Mexican government implemented taxes to reduce the consumption of sugar-sweetened beverages and nonessential energy-dense foods. In this manuscript, we analyze the scientific evidence linking the consumption of these products to chronic diseases, and summarize the studies that have evaluated the observed and expected impact of food taxes in Mexico. The implementation of taxes to unhealthy foods has reduced purchases of sugar-sweetened beverages in 7. Read More

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March 2018
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Functional, nutritional and social factors associated with mobility limitations in the elderly: a systematic review.

Salud Publica Mex 2018 Sep-Oct;60(5):579-585

Postgraduate Program in Collective Health, Odontology Department, Federal University of Rio Grande do Norte. Natal, Brazil.

Objective: To systematically review the prevalence and incidence of mobility limitations in the elderly people and their associated factors.

Materials And Methods: Articles in the electronic literature were searched via PubMed, Scopus,,Lilacs, SciELO, PAHO, MedCarib, Repidisca, Wholis, IBCES, PEDro, Medline and Bireme (2012-2016). The instrument STROBE was used to analyze the quality of the work and the PRISMA recommendation was used to structure the review. Read More

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September 2017

[Social determinants of the health of international migrant children in Chile: qualitative evidence.]

Salud Publica Mex 2018 Sep-Oct;60(5):566-578

Programa de Estudios Sociales en Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo. Santiago, Chile.

Objective: To explore the social determinants of health (SDH) of international migrant children, from the perceptions of caregivers, health workers and local authorities in eight municipalities in Chile.

Materials And Methods: A secondary analysis of data was conducted from a qualitative study that took place between 2014 and 2017. The original study involved semi-structured interviews and focus groups. Read More

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[Social participation and health: a collaborative experience on chronic kidney disease.]

Salud Publica Mex 2018 Sep-Oct;60(5):559-565

School of Kinesiology and Health Studies, Queen's University. Kingston, Canada.

Objective: To identify challenges derived from renal insufficiency, as well as potential solutions and an agenda for action.

Materials And Methods: y adopting a collaborative research approach, diverse stakeholders -sick people, family members, advocacy groups, health professionals, and academics- participated in two gatherings in the context of the World Kidney Day in Guadalajara, Mexico and created an agenda for action. Data was gathered through group discussions. Read More

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Enhancing smoking cessation in Mexico using an e-Health tool in primary healthcare.

Salud Publica Mex 2018 Sep-Oct;60(5):549-558

Department of Biomedical Research, Medical Center, Hackensack University. Hackensack, NJ, US.

Objective: To evaluate an e-Health tool designed to enhance smoking cessation in Mexico in primary healthcare.

Materials And Methods: Smokers 18 years of age and older were recruited in the waiting room of two primary healthcare clinics in Mexico City. Participants used an eHealth smoking cessation tool that included smoking-related assessments, education on pharmacotherapy, and motivational videos. Read More

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December 2017
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[Validation of a short Spanish version of the instrument Barriers to Physical Activity Questionnaire for People with Mobility Impairments.]

Salud Publica Mex 2018 Sep-Oct;60(5):539-548

Departamento de Educación Física y Deportiva, Universitat de València. España.

Objective: To validate a short Spanish version of the instrument Barriers to Physical Activity Questionnaire for People with Mobility Impairments (BPAQ-MI), applicable to different types of disability.

Materials And Methods: The questionnaire was administered to 791 university students with disabilities. The factorial structure was validated by confirmatory factor analysis and Spearman correlations were carried out to assess criterion validity. Read More

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February 2017

[Psychometric validation of an instrument to evaluate the context of quality improvement and accreditation of hospitals].

Salud Publica Mex 2018 Sep-Oct;60(5):528-538

Instituto Nacional de Salud Pública. México.

Objective: To adapt and validate an instrument to measure the context factors which favor quality improvement initiatives and accreditation of hospitals.

Materials And Methods: The model and questionnaire Model for Understanding Success in Quality (MUSIQ) is adapted and validated for application in Spanish-speaking countries and its specific use in hospital accreditation projects. The theoretical construct of its dimensions is assessed by confirmatory factor analysis (Bartlett test and Kaiser-Meyer-Olkim index) and internal consistency (Cronbach's a), in a study carried out in a sample of 54 hospitals of medium and high complexity in Colombia. Read More

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October 2017