40,718 results match your criteria Salmonellosis


Protective Effects of Xyloglucan in Association with the Polysaccharide Gelose in an Experimental Model of Gastroenteritis and Urinary Tract Infections.

Int J Mol Sci 2018 Jun 22;19(7). Epub 2018 Jun 22.

Department of Chemical, Biological, Pharmacological and Environmental Sciences, University of Messina, 31-98166 Messina, Italy.

Acute infectious gastroenteritis (GE) and urinary tract infection (UTI) are common diseases and are normally perceived as mild and limiting illnesses. Xyloglucan is a natural plant polymer with protective barrier properties, also known as “mucosal protectors”, which is the main ingredient of medical devices developed for the management of different diseases, such as gastrointestinal diseases, urinary tract infections, or respiratory allergic diseases. The aim of this study was to evaluate the protective effect of xyloglucan in association with gelose (also called agar) in an experimental model of bacterial GE and UTI in rats. Read More

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Climate variability and salmonellosis in Singapore - A time series analysis.

Sci Total Environ 2018 Oct 26;639:1261-1267. Epub 2018 May 26.

Biostatistics Unit, Dunedin School of Medicine, University of Otago, Ground Floor, Adams Building, 18 Frederick Street, Dunedin 9016, New Zealand.

Climate change is expected to bring about global warming and an increase in the frequency of extreme weather events. This may consequently influence the transmission of food-borne diseases. The short term associations between climatic conditions and Salmonella infections are well documented in temperate climates but not in the tropics. Read More

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October 2018

Antibacterial Activity of Thai Medicinal Plant Extracts Against Microorganism Isolated from Post-Weaning Diarrhea in Piglets.

J Med Assoc Thai 2016 Jul;99 Suppl 4:S203-10

Background: Post-weaning bacterial infections in piglets caused by resistant strains have increased dramatically. Thai medicinal plants such as Piper retrofractum, Piper leptostachyum, Piper sarmentosum, Zingiber officinale, Plumbago indica, Piper betle, Caesalpinia sappan, Garcinia mangostana etc have been widely used in Thai traditional medicine to treat diarrhea. Thus, these plants were investigated antimicrobial activity against gram negative strain isolated from piglets with diarrhea. Read More

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Deletions in guaBA and htrA but not clpX or rfaL constitute a live-attenuated vaccine strain of Salmonella Newport to protect against serogroup CC Salmonella in mice.

Hum Vaccin Immunother 2018 Jun 21. Epub 2018 Jun 21.

a Center for Vaccine Development and Institute for Global Health, Department of Medicine , University of Maryland School of Medicine , Baltimore , MD , USA.

Non-typhoidal Salmonella (NTS) are a leading cause of foodborne infections worldwide, and serogroups B, C, CC and D are the most common serogroups associated with human disease. While live vaccine candidates that protect against S. Typhimurium (serogroup B) and S. Read More

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June 2018
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Antibiotic Resistance in Salmonella Enteritidis Isolates Recovered from Chicken, Chicken Breast, and Humans Through National Antimicrobial Resistance Monitoring System Between 1996 and 2014.

Foodborne Pathog Dis 2018 Jun 21. Epub 2018 Jun 21.

1 CATG Microbiology & Food Safety Laboratory, Institute of Preventive Veterinary Medicine, College of Animal Sciences of Zhejiang University , Hangzhou, China .

Salmonella enterica subspecies enterica serotype Enteritidis (S. Enteritidis) is one of the leading causes for human salmonellosis all over the world. We analyzed the surveillance data of 18 years on antimicrobial resistance profiling of S. Read More

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Use of gender distribution in routine surveillance data to detect potential transmission of gastrointestinal infections among men who have sex with men in England.

Epidemiol Infect 2018 Jun 20:1-10. Epub 2018 Jun 20.

Field Epidemiology Service,Public Health England,London,UK.

Detecting gastrointestinal (GI) infection transmission among men who have sex with men (MSM) in England is complicated by a lack of routine sexual behavioural data. We investigated whether gender distributions might generate signals for increased transmission of GI pathogens among MSM. We examined the percentage male of laboratory-confirmed patient-episodes for patients with no known travel history for 10 GI infections of public health interest in England between 2003 and 2013, stratified by age and region. Read More

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Antimicrobial effect of Licochalcone A and Epigallocatechin-3-gallate against Typhimurium isolated from poultry flocks.

Iran J Microbiol 2018 Feb;10(1):51-58

Department of Microbiology, Faculty of Veterinary Medicine, Tehran University, Tehran, Iran.

Background And Objectives: Salmonellosis due to multi-drug resistant Typhimurium with biofilm formation ability is a serious public health threat worldwide. Studies have shown that medicinal plants inhibit the growth of bacterial species. The present study aimed at determining antibiotic resistance pattern and biofilm formation ability of Typhimurium isolated from poultry flocks. Read More

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February 2018

Enteritidis and Typhimorium identification in poultry carcasses.

Iran J Microbiol 2018 Feb;10(1):45-50

Department of Food Hygiene, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.

Background And Objectives: Salmonellosis caused by spp. is one of the most important zoonotic diseases and transmits to human through raw food animal products including poultry meat. serovar Enteritidis and serovar Typhimurium are the most important strains that infect human. Read More

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February 2018
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Analysis of consumer food purchase data used for outbreak investigations, a review.

Euro Surveill 2018 Jun;23(24)

Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.

BackgroundInvestigations of food-borne outbreaks are frequently unsuccessful and new investigation methods should be welcomed. Describe the use of consumer purchase datasets in outbreak investigations and consider methodological and practical difficulties. We reviewed published papers describing the use of consumer purchase datasets, where electronic data on the foods that case-patients had purchased before onset of symptoms were obtained and analysed as part of outbreak investigations. Read More

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Clinical Course, Outcomes and Complications of Thai Pediatric Pure Type versus Mixed Type Lupus Membranous Nephritis.

J Med Assoc Thai 2017 Feb;100(2):158-66

Background: Due to the relative infrequency of lupus membranous nephritis (LMN) compared to other types of lupus nephritis (LN) in pediatric patients, the current literature on pediatric LMN is limited. The knowledge regarding clinical manifestations, outcomes and infectious complications are mainly based on studies in the adult population. Similar to disease expression in SLE, the renal manifestations of LMN are affected by environmental factors and vary among racial and ethnic groups. Read More

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February 2017

Role of systemic infection, cross contaminations and super-shedders in Salmonella carrier state in chicken.

Environ Microbiol 2018 Jun 19. Epub 2018 Jun 19.

ISP, INRA, Université François Rabelais de Tours, ULR 1282, 37380 Nouzilly, France.

Carriage of Salmonella is often associated with a high level of bacterial excretion and generally occurs after a short systemic infection. However, we do not know whether this systemic infection is required or whether the carrier-state corresponds to continuous reinfection or real persistence in caecal tissue. The use of a Salmonella Enteritidis bamB mutant demonstrated that a carrier-state could be obtained in chicken in the absence of systemic infection. Read More

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Microbial Source Tracking of Cronobacter spp.

Authors:
Steve Forsythe

Adv Appl Microbiol 2018 16;103:49-101. Epub 2018 Mar 16.

Adams Hill, Keyworth, United Kingdom. Electronic address:

Being able to track bacterial pathogens is essential for epidemiological purposes as well as monitoring in-house production facilities. Common bacterial pathogens, such as Salmonella serovars, are already been well defined, and their detection methods are very advanced. However, this will not be the case for emergent bacterial pathogens, as was the case for Cronobacter. Read More

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March 2018
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Fecal carriage of antimicrobial-resistant in healthy Korean adults.

J Microbiol Biotechnol 2018 May 8. Epub 2018 May 8.

Department of Molecular Cell Biology and Samsung Medical Center, Sungkyunkwan University School of Medicine, Suwon, Korea.

The spread of antibiotic-resistant the community is one of the main challenges for antibiotic treatment of community-onset infections. We evaluated the microbiological and molecular characteristics of stool samples from adults with comprehensive health examinations. Of 109 fecal samples, bacterial growth was observed in 86 samples and 61 Gram-negative bacterial isolates were identified, of which 45 were isolates (73. Read More

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[Mexican case of tinea incognito and granuloma de Majocchi acquired from a hedgehog].

Rev Chilena Infectol 2018 Apr;35(2):204-206

Sección de Micología, Hospital General Dr. Manuel Gea. González, Ciudad de México, México.

Exotic pets, such as the ground hedgehog, are capable of transmitting to the human being different zoonoses, such as salmonellosis, mycobacteria, protozoa such as Cryptosporidium parvum, and dermatophytosis. We present the case report of a male adult patient, who had recently acquired a ground hedgehog, who presented in his hand a ringworm lesion incognito and a Majocchi granuloma. The etiological agent was identified as Trichophyton erinacei by mycological culture and molecular biology. Read More

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April 2018
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Effects of 1,8-cineole on Carbohydrate Metabolism Related Cell Structure Changes of .

Front Microbiol 2018 25;9:1078. Epub 2018 May 25.

Key Laboratory of Animal Protein Deep Processing Technology of Zhejiang Province, Ningbo University, Zhejiang, China.

is gram-negative foodborne zoonotic bacteria which triggers disease in humans. Our previous studies showed 1,8-cineole possessed remarkable antimicrobial effects on foodborne zoonotic bacteria indicating it could serve as a new source of antibiotic for . Present study elucidated the antibacterial mechanism of 1,8-cineole by analyzing serum protein expressed by following treatment with 1,8-cineole (0. Read More

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May 2018
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[Antimicrobial resistance analysis and mechanism of Salmonella recovered from retail chicken carcasses in Beijing in summer, 2013].

Wei Sheng Yan Jiu 2017 Jul;46(4):538-545

Key Laboratory of Food Safety Risk Assessment of Health, China National Center for Food Safety Risk Assessment, Beijing 100021, China.

Objective: Research were carried out to determine the antimicrobial resistance and mechanism of Salmonella isolates recovered from retail chicken carcasses in Beijing in summer, 2013.

Methods: Broth microdilution method were used for antimicrobial susceptibility testing to obtain the minimal inhibitory concentration( MICs)against 11 antimicrobial compounds which belongs to 8 categories and 166 Salmonella strains isolated from 33 retail chicken carcasses in Beijing in summer, 2013 were tested. Cephalosporin resistant isolates were evaluated by ESBLs confirmation test, also resistance mechanism analysis was subjected to ciprofloxacin and cefotaxime co-resistant Salmonella isolates. Read More

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Occurrence, antimicrobial susceptibility patterns and genotypic relatedness of Salmonella spp. isolates from captive wildlife, their caretakers, feed and water in India.

Epidemiol Infect 2018 Jun 14:1-7. Epub 2018 Jun 14.

Division of Animal Science,Krishi Bhavan,New Delhi,India.

Occurrence of Salmonella spp. in captive wild animal species in India is largely unknown. The purpose of this study was to determine the occurrence of different Salmonella serotypes, antimicrobial resistance patterns and genotypic relatedness of recovered isolates. Read More

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4-Thiazolidinone coumarin derivatives as two-component NS2B/NS3 DENV flavivirus serine protease inhibitors: synthesis, molecular docking, biological evaluation and structure-activity relationship studies.

Chem Cent J 2018 Jun 12;12(1):69. Epub 2018 Jun 12.

School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800, Penang, Malaysia.

A series of novel 4-thiazolidinone inhibitors SKYa-SKYg, containing coumarin as a core structure were synthesized via facile and efficient method. The structures of the synthesized compounds were established by extensive spectroscopic studies (FT IR, 1D NMR, 2D NMR, LC-MS) and elemental analysis. All the synthesized hybrids were further evaluated for their potential as anti-tubercular agents against Mycobacterium tuberculosis H37Rv ATCC 25618, and anti-bacterial agents against Escherichia coli, Enterobacter aerogenes, Salmonella typhi, Streptococcus pneumoniae and Staphylococcus aureus. Read More

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June 2018
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Arthropod Borne and Zoonotic Infections Among Military Personnel in Georgia.

J Spec Oper Med 2018 ;18(2):136-140

Military personnel are at an increased risk for exposure to arthropod- borne and zoonotic pathogens. The prevalence of these pathogens has not been adequately described in the country of Georgia. As the Georgian military moves toward an increased level of capability and the adoption of European Union and North Atlantic Treaty Organization standards, international field exercises will become more frequent and will likely involve an increasing number of international partners. Read More

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January 2018

High precision microfluidic microencapsulation of bacteriophages for enteric delivery.

Res Microbiol 2018 Jun 7. Epub 2018 Jun 7.

Chemical Engineering Department, Loughborough University, Loughborough LE11 3TU, United Kingdom. Electronic address:

A Salmonella specific bacteriophage Felix O1 (Myoviridae) was microencapsulated in a pH responsive polymer formulation. The formulation incorporated a pH responsive methacrylic acid copolymer Eudragit® S100 (10% (w/v)) with the addition of the biopolymer sodium alginate, the composition of which was varied in the range (0.5% (w/v) - 2% (w/v)). Read More

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and salmonellosis in horses: an overview.

Authors:

Vet Rec 2018 06;182(23):659-660

, and of the APHA discuss the diagnosis, prevention and control of salmonellosis in horses. Read More

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Antibody titers in turkeys increase after multiple booster vaccinations with an attenuated Salmonella live vaccine.

BMC Res Notes 2018 Jun 8;11(1):367. Epub 2018 Jun 8.

Clinic for Poultry, University of Veterinary Medicine Hannover, Bünteweg 17, Hannover, Germany.

Objective: Human Salmonellosis is one of the most frequently reported foodborne zoonoses in the European Union. The most common source of human infections is the consumption of poultry products. Besides management and hygiene practices vaccination of poultry livestock is seen as one way to reduce Salmonella infections in humans. Read More

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June 2018
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Characterization of a novel multidrug resistance plasmid pSGB23 isolated from subspecies enterica serovar Saintpaul.

Gut Pathog 2018 4;10:20. Epub 2018 Jun 4.

2Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University, Singapore, 637551 Singapore.

Background: subspecies enterica serovar Saintpaul (. Saintpaul) is an important gut pathogen which causes salmonellosis worldwide. Although intestinal salmonellosis is usually self-limiting, it can be life-threatening in children, the elderlies and immunocompromised patients. Read More

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Integrin αβ (CD11d/CD18) Modulates Leukocyte Accumulation, Pathogen Clearance, and Pyroptosis in Experimental Typhimurium Infection.

Front Immunol 2018 24;9:1128. Epub 2018 May 24.

Laboratório de Immunofarmacologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.

β integrins are critical in host defense responses to invading pathogens and inflammation. Previously, we reported that genetic deficiency of integrin αβ in mice altered outcomes in experimental systemic infections including accelerated mortality in animals infected with serovar Typhimurium. Here, we show that deficiency of αβ results in impaired accumulation of leukocytes in response to peritoneal infection by . Read More

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May 2018
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Multistate outbreak of Salmonella Paratyphi B variant L(+) tartrate(+) and Salmonella Weltevreden infections linked to imported frozen raw tuna: USA, March-July 2015.

Epidemiol Infect 2018 Jun 8:1-7. Epub 2018 Jun 8.

Centers for Disease Control and Prevention (CDC),Atlanta, Georgia,USA.

Foodborne non-typhoidal salmonellosis causes approximately 1 million illnesses annually in the USA. In April 2015, we investigated a multistate outbreak of 65 Salmonella Paratyphi B variant L(+) tartrate(+) infections associated with frozen raw tuna imported from Indonesia, which was consumed raw in sushi. Forty-six (92%) of 50 case-patients interviewed ate sushi during the week before illness onset, and 44 (98%) of 45 who specified ate sushi containing raw tuna. Read More

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June 2018
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Engineering of a rough auxotrophic mutant Typhimurium for effective delivery.

Oncotarget 2018 May 22;9(39):25441-25457. Epub 2018 May 22.

College of Veterinary Medicine, Chonbuk National University, Iksan Campus, Iksan 54596, Republic of Korea.

Live vaccine vectors offer a remarkable platform for delivering immunogens and therapeutic molecules by mimicking natural intracellular infections; however, pre-existing anti-vector immunity can impede effective deployment. Measures to alleviate pre-existing immunity include the use of heterologous vectors, development of highly attenuated strain enabling greater payload, removal of major immunoreactive components from the vector, and/or augmentation of delivered antigens via increased presentation in antigen presenting cells. Here we report a Typhimurium (ST) vector-JOL1800 that embodies these requisite properties. Read More

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May 2018
2 Reads

[A rare and atypical cause of scrotal ulcerations].

Pan Afr Med J 2018 30;29:87. Epub 2018 Jan 30.

Service de Dermatologie-Vénéréologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc.

Salmonelloses are bacterial infections of the faecal peril; they are endemic in some regions of the world. They can colonize almost any organ hematogenously, hence, severe forms may be observed. We report a case of typhoid fever in a 16-year old young adolescent with no medical history, sexually transmitted diseases or sexual intercourses, presenting with necrotic scrotal ulcerations evolving over the past 3 weeks in a context of fever, diarrhoea, weight loss and alteration of the general state. Read More

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Enteric pathogens and associated risk factors among under-five children with and without diarrhea in Wegera District, Northwestern Ethiopia.

Pan Afr Med J 2018 24;29:72. Epub 2018 Jan 24.

Faculty of Medicine, Addis Ababa University, Ethiopia.

Introduction: Childhood diarrhea is highly prevalent in slums in developing countries, but it remains understudied. The objectives of this study were to explore the prevalence of , rotavirus and bacterial enteropathogens among diarrheic and non-diarrheic children and investigate socio-environmental determinants of diarrhea in two Ethiopian towns.

Methods: A cross-sectional study was conducted from June to October 2016. Read More

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[Antibiotic resistance of Salmonella spp strains isolated from blood cultures in Bukavu, Democratic Republic of the Congo].

Pan Afr Med J 2018 17;29:42. Epub 2018 Jan 17.

International Center for Advanced Research and Training, Bukavu, RD Congo.

Introduction: Typhoid fever is a major public health problem in developing countries because of the obsolescence of health infrastructure and of an almost non-existent water distribution network. In the Democratic Republic of the Congo, in general, and in Bukavu, in particular, blood culture is inaccessible to the majority of patients. This study aimed to assess the sensitivity of Salmonella spp to antibiotics commonly used for the tratment of typhoid fever in Bukavu. Read More

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June 2018
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Evaluation of a multiplex PCR method to serotype in animal feeds pre-enrichment broth cultures.

MethodsX 2017 20;4:335-345. Epub 2017 Sep 20.

U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, Laurel, MD 207081, United States.

The identification of serotypes remains a highly important public health concern for microbiological analysis of foods, feeds, and clinical samples. Outbreaks of human salmonellosis are sometimes linked to contact with infected animals and animal feeds. To possibly reduce the number of outbreaks, it is important to rapidly, efficiently detect in animal feeds and food products. Read More

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September 2017
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Hematological abnormalities in patients with malaria and typhoid in Tamale Metropolis of Ghana.

BMC Res Notes 2018 Jun 5;11(1):353. Epub 2018 Jun 5.

Department of Biochemistry & Molecular Medicine, School of Medicine and Health Sciences, University for Development Studies, P. O. Box TL 1883, Tamale, Ghana.

Objective: Anemia, Leukopenia, and thrombocytopenia are commonly observed hematological abnormalities in malaria and typhoid patients. In this study, we evaluated the prevalence of cytopenias in patients with mono-infections of plasmodium parasites (malaria group) or salmonella bacteria (typhoid group). Full blood counts from 79 patients (age ranging from 18 to 77 years) categorized into malaria and typhoid groups at the Tamale Central Hospital were assessed. Read More

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June 2018
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Stimulator of Interferon Genes in Classical Dendritic Cells Controls Mucosal Th17 Responses to Cyclic Dinucleotides for Host Defenses Against Microbial Infections in Gut.

Front Immunol 2018 16;9:1085. Epub 2018 May 16.

Department of General Surgery, Nanjing Drum Tower Hospital, Nanjing, China.

Cyclic dinucleotides are bacterial signal transducers that bind to host intracellular protein, stimulator of interferon genes (STING) encoded by . In this study, we demonstrate that STING triggers adaptive immune responses that control Th17 differentiation. Cyclic dinucleotides recognition enables classical dendritic cells (cDCs) that predominantly express CD103 to induce Th17 lymphocytes in an IL-6/IL-1β-dependent manner in gut. Read More

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May 2018
2 Reads

The Herbal Compound Thymol Protects Mice From Lethal Infection by Typhimurium.

Front Microbiol 2018 16;9:1022. Epub 2018 May 16.

Key Laboratory of Zoonosis, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.

Type III secretion system (T3SS) is an essential pathogenic determinant for many important bacterial pathogens; it functions to thwart immune defense by delivering effectors into host cells. Because of its essential role in bacterial virulence, this machinery is an important target in the development of novel anti-virulence therapeutics. By using an effector-lactamase fusion reporter, we identified thymol, a monoterpene phenol derivative of cymene, as an effective inhibitor of the T3SS-1 of Typhimurium. Read More

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May 2018
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Genome-Wide Comparative Functional Analyses Reveal Adaptations of sv. Newport to a Plant Colonization Lifestyle.

Front Microbiol 2018 18;9:877. Epub 2018 May 18.

Soil and Water Sciences Department, University of Florida, Gainesville, FL, United States.

Outbreaks of salmonellosis linked to the consumption of vegetables have been disproportionately associated with strains of serovar Newport. We tested the hypothesis that strains of sv. Newport have evolved unique adaptations to persistence in plants that are not shared by strains of other serovars. Read More

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DO ALL PATIENTS WITH SALMONELLA INFECTIONS REQUIRE A 'PET' SCAN?

Ulster Med J 2018 May 30;87(2):134-135. Epub 2018 May 30.

Consultant, Department of Haematology Belfast City Hospital.

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Differential Effects of Statins on Inflammatory Interleukin-8 and Antimicrobial Peptide Human Β-Defensin 2 Responses in -Infected Intestinal Epithelial Cells.

Int J Mol Sci 2018 Jun 2;19(6). Epub 2018 Jun 2.

Department of Pathology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.

Alternative therapies are needed to reduce the use of antibiotics and incidence of drug-resistant . Previous studies have revealed important roles of statins in regulating innate immunity. Therefore, we investigated the effects of statins on innate immunity in -infected intestinal epithelial cells (IECs), which are involved in mucosal innate immunity. Read More

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June 2018
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Multi-epitope DnaK peptide vaccine against S.Typhi: An in silico approach.

Vaccine 2018 06 1;36(28):4014-4022. Epub 2018 Jun 1.

Defence Institute of Physiology and Allied Sciences, Lucknow Road, Timarpur, Delhi 110054, India. Electronic address:

Salmonella is one of the key global causes of food and water borne enteric infections, responsible for significant morbidity and mortality worldwide especially in developing countries. Currently available vaccines against typhoid are moderately effective with several side effects and not efficacious against all Salmonella serovars. Due to limitations of these vaccines and emerging threats of multidrug resistance, developing an effective vaccine against these infections has increasingly become a priority. Read More

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June 2018
2 Reads

[Etiology of bacterial diarrhea in large cities, mid-sized/small cities and rural areas of China].

Zhonghua Liu Xing Bing Xue Za Zhi 2018 May;39(5):651-655

National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.

To understand the etiological characteristics of bacterial diarrhea in different areas, including large cities, mid-sized/small cities and rural area, in China. A cross-sectional surveillance was conducted in 17 provinces of China from 2010 to 2014. The acute diarrhea outpatients were selected from clinics or hospitals in large cities, mid-sized/small cities, including rural-urban fringe zones, and rural areas. Read More

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A Rare Case of Mediastinal Bronchogenic Cyst Infected by .

Case Rep Pulmonol 2018 9;2018:9121389. Epub 2018 May 9.

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Wayne State University, Detroit, MI, USA.

Bronchogenic cysts are rare congenital malformations which arise from abnormal budding of the primitive tracheobronchial tube and can localize to either the mediastinum or lung parenchyma. They remain clinically silent in most adults unless they become infected or are large enough to compress adjacent structures. Infections involving bronchogenic cysts are often polymicrobial. Read More

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May 2018
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Effect of Fractioning on Antibacterial Activity of Oliver (Annonaceae) Methanol Extract and Mode of Action.

Evid Based Complement Alternat Med 2018 29;2018:4831593. Epub 2018 Apr 29.

Faculty of Sciences, University of Douala, P.O. Box 24157, Douala, Cameroon.

Infectious diseases caused by bacteria constitute the main cause of morbidity and mortality throughout the world and mainly in developing countries. In this work, the influence of fractioning and the mode of action of stem barks methanol extract of were investigated. The aim was to optimize the antibacterial activity of the methanol extract. Read More

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Antimicrobial Resistance and Molecular Characterization of Salmonella enterica Serovar Enteritidis from Retail Chicken Products in Shanghai, China.

Foodborne Pathog Dis 2018 Jun 30;15(6):346-352. Epub 2018 May 30.

1 MOST-USDA Joint Research Center for Food Safety, School of Agriculture & Biology, State Key Lab of Microbial Metabolism, Shanghai Jiao Tong University , Shanghai, China .

Salmonella enterica serovar Enteritidis is the leading global cause of salmonellosis. A total of 146 Salmonella Enteritidis isolates obtained from retail chicken products in Shanghai, China were characterized for their antimicrobial susceptibilities, virulence and antibiotic resistance gene profiles, and molecular subtypes using pulsed-field gel electrophoresis (PFGE). Approximately 42% (61/146) of the isolates were susceptible to all 13 antimicrobials tested. Read More

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Intestinal lamina propria CD4T cells promote bactericidal activity of macrophages via galectin-9 and Tim-3 interaction during infection.

Infect Immun 2018 May 29. Epub 2018 May 29.

Institute of Immunopharmacology and Immunotherapy, School of Pharmaceutical Sciences, Shandong University, Jinan, China

The intestinal immune system is crucial for protection from pathogenic infection and maintenance of mucosal homeostasis. Here, we studied the intestinal immune microenvironment in a intestinal infection mouse model. Intestinal lamina propria macrophages are the main effector cells in innate resistance to intracellular microbial pathogens. Read More

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Imported edible leaves collected at retail sale in England during 2017 with an emphasis on betel and curry leaves: Microbiological quality with respect to Salmonella, Shiga-toxin-producing E. coli (STEC) and levels of Escherichia coli.

J Appl Microbiol 2018 May 26. Epub 2018 May 26.

Public Health England Food Water and Environmental Microbiology Laboratory Porton, National Infection Service, Porton Down, Salisbury, SP4 0JG, UK.

Aims: to investigate the microbiological quality of imported fresh leaves on retail-sale during 2017 with respect to Salmonella, Shiga-toxin-producing Escherichia coli (STEC) and levels of E.coli.

Methods And Results: 279 samples of imported edible leaves (69 banana, 77 betel, 118 curry and 15 other types) were tested. Read More

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The development of a screening protocol for Salmonella spp. and enteropathogenic Yersinia spp. in samples from wild boar (Sus scrofa) also generating MLVA-data for Y. enterocolitica and Y. pseudotuberculosis.

J Microbiol Methods 2018 Jul 21;150:32-38. Epub 2018 May 21.

Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden; Department of Microbiology, National Veterinary Institute, Uppsala, Sweden. Electronic address:

Salmonellosis and yersiniosis are notifiable human diseases that are commonly associated with contaminated food. Domestic pigs as well as wild boars and other wild-life have been identified as reservoirs of these bacteria. Methods for cultivation and molecular epidemiological investigations of Salmonella spp. Read More

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July 2018
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Antibiotic resistance and molecular characterization of diarrheagenic Escherichia coli and non-typhoidal Salmonella strains isolated from infections in Southwest China.

Infect Dis Poverty 2018 May 7;7(1):53. Epub 2018 May 7.

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, 200025, People's Republic of China.

Background: Bacterial diarrhea is one of the most common causes for medical consultations, mortality and morbidity in the world. Diarrheagenic Escherichia coli (DEC) and non-typhoidal Salmonella (NTS) are major intestinal pathogens in developing countries, and the indiscriminate use of antibiotics has greatly contributed to resistant strains. Hence, the aim of the present study is to identify the antimicrobial resistance patterns and the molecular characteristics of DEC and NTS in southwest, China. Read More

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Immunogenicity and efficacy following sequential parenterally-administered doses of Salmonella Enteritidis COPS:FliC glycoconjugates in infant and adult mice.

PLoS Negl Trop Dis 2018 05 23;12(5):e0006522. Epub 2018 May 23.

Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.

In sub-Saharan Africa, invasive nontyphoidal Salmonella (iNTS) infections with serovars S. Enteritidis, S. Typhimurium and I 4,[5],12:i:- are widespread in children < 5 years old. Read More

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Commercial Frozen Mice Used by Owners to Feed Reptiles are Highly Externally Contaminated with Salmonella Enteritidis PT8.

Vector Borne Zoonotic Dis 2018 May 23. Epub 2018 May 23.

2 Department of Bacteriology, Animal and Plant Health Agency , Surrey, Addlestone, United Kingdom .

Salmonella remains one of the most prevalent zoonoses worldwide. Although salmonellosis is commonly associated with the consumption of contaminated food, it has been estimated that up to 11% of Salmonella infections overall are acquired from direct or indirect contact with animals, including reptiles. In 2016, an outbreak of Salmonella Enteritidis involving multiple cases, especially children, associated with reptile contact and contaminated feeder mice was reported in the United Kingdom. Read More

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Typhoidal Salmonella serovars: Ecological opportunity and the evolution of a new pathovar.

FEMS Microbiol Rev 2018 May 21. Epub 2018 May 21.

Department of Medial Microbiology and Immunology, School of Medicine, University of California Davis, Davis, CA, USA.

Typhoid and paratyphoid fever are severe systemic infections caused by human-adapted typhoidal Salmonella serovars that are indistinguishable in their clinical presentation, but differ from human gastroenteritis caused by zoonotic non-typhoidal Salmonella serovars. Typhoidal Salmonella serovars evolved from ancestral gastrointestinal pathogens through genetic changes that supported a change in pathogen ecology. Typhoidal Salmonella serovars share virulence properties that were acquired through convergent evolution and therefore this group is not defined by the presence of shared virulence genes that are absent from non-typhoidal Salmonella serovars. Read More

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Effects of Psidium guajava leaf extract on secretion systems of Gram-negative enteropathogenic bacteria.

Microbiol Immunol 2018 May 23. Epub 2018 May 23.

Department of Bacteriology, Graduate School of Medicine, University of the Ryukyus, Nishihara, Okinawa 903- 0215, Japan.

We screened a total of 672 plant-tissue extracts to search for phytochemicals that inhibit the function of the type III secretion system (T3SS) of enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC). Among candidates examined, we found that an extract from the leaves of Psidium guajava (guava) inhibited the secretion of the EspB protein from EPEC and EHEC without affecting bacterial growth. Read More

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Negligible import of enteric pathogens by newly-arrived asylum seekers and no impact on incidence of notified and infections and outbreaks in Rhineland-Palatinate, Germany, January 2015 to May 2016.

Euro Surveill 2018 May;23(20)

Department of Infectious Diseases, Medical Microbiology and Hygiene, University Hospitals, Heidelberg, Germany.

IntroductionThe 2015 refugee crisis raised concerns about an import of infectious diseases affecting the German population. To evaluate public and individual health benefits of stool screening, and explore whether importation of enteric pathogens by newly-arrived asylum seekers impacts on the host population. : We used data from mandatory stool screening to determine the overall, age, sex, and country-specific prevalence of enteric bacteria and helminths. Read More

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May 2018
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