41,729 results match your criteria Salmonellosis


The use of aminoglycosides in animals within the EU: development of resistance in animals and possible impact on human and animal health: a review.

J Antimicrob Chemother 2019 Apr 19. Epub 2019 Apr 19.

Veterinary Medicines Directorate, Addlestone, UK.

Aminoglycosides (AGs) are important antibacterial agents for the treatment of various infections in humans and animals. Following extensive use of AGs in humans, food-producing animals and companion animals, acquired resistance among human and animal pathogens and commensal bacteria has emerged. Acquired resistance occurs through several mechanisms, but enzymatic inactivation of AGs is the most common one. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jac/dkz161DOI Listing

UltraStrain: An NGS-Based Ultra Sensitive Strain Typing Method for .

Front Genet 2019 3;10:276. Epub 2019 Apr 3.

Aginome-XMU Joint Lab, Xiamen University, Xiamen, China.

In the last few years, advances in next-generation sequencing (NGS) technology for whole genome sequencing (WGS) of foodborne pathogens have provided drastic improvements in food pathogen outbreak surveillance. WGS of foodborne pathogen enables identification of pathogens from food or environmental samples, including difficult-to-detect pathogens in culture-negative infections. Compared to traditional low-resolution methods such as the pulsed-field gel electrophoresis (PFGE), WGS provides advantages to differentiate even closely related strains of the same species, thus enables rapid identification of food-source associated with pathogen outbreak events for a fast mitigation plan. Read More

View Article

Download full-text PDF

Source
https://www.frontiersin.org/article/10.3389/fgene.2019.00276
Publisher Site
http://dx.doi.org/10.3389/fgene.2019.00276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456706PMC
April 2019
1 Read

Invasive Salmonella infections among children in Bintulu, Sarawak, Malaysian Borneo: a 6-year retrospective review.

BMC Infect Dis 2019 Apr 18;19(1):330. Epub 2019 Apr 18.

Institute of Health and Community Medicine, Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia.

Background: Invasive Salmonella infections result in significant morbidity and mortality in developing countries. In Asia, typhoid and paratyphoid fever are reported to be the major invasive Salmonella infections, while invasive non-typhoidal Salmonella (iNTS) infections are believed to be uncommon. Data from Sarawak, in Malaysian Borneo, are limited. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12879-019-3963-xDOI Listing

A Retrospective Epidemiological Study of the Incidence and Risk Factors of Salmonellosis in Bahrain in Children During 2012⁻2016.

Pathogens 2019 Apr 17;8(2). Epub 2019 Apr 17.

Department of Biology, College of Science, University of Bahrain, Sakhir Campus, Sakhir 976, Bahrain.

Salmonellosis is one of the major public health concerns in Bahrain as it has increased rapidly during the past few years. This study aims to determine the prevalence of salmonellosis in children and the possible risk factors such as age, geographical area, nationality, gender, unsafe drinking water, infant born weight and gastrointestinal disease. The cases of salmonellosis in children reported by the Ministry of Health of Bahrain ranged from 21 to 26 per 100,000 population during the period 2012-2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/pathogens8020051DOI Listing

Evaluation of Lactobacillus spp. and yeast based probiotic (Lavipan) supplementation for the reduction of Salmonella Enteritidis after infection of broiler chickens.

Pol J Vet Sci 2019 Mar;22(1):5-10

Department of Poultry Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13, 10-719 Olsztyn, Poland.

The number of human cases of salmonellosis in the EU was 94,625 in 2015. Considering the source of these infections, Salmonella spp. was most frequently detected in broiler chicken meat and Salmonella Enteritidis (SE) was the most commonly reported serovar. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.24425/pjvs.2018.125616DOI Listing

Poultry: a receptacle for non-typhoidal Salmonellae and antimicrobial resistance.

Iran J Microbiol 2019 Feb;11(1):31-38

Enteric Diseases Division, Department of Microbiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India.

Background And Objectives: Non-typhoidal Salmonellosis, a zoonotic infection associated with acute gastroenteritis is caused by non-typhoidal salmonellae (NTS). The study was carried out to determine the prevalence of NTS serovars and their antimicrobial resistance along with the presence of the virulence gene ( gene) in poultry samples.

Materials And Methods: This is a prospective cross-sectional study carried out at the Enteric Diseases Division, Kasturba Medical College, Manipal, South India from January 2016- December 2017. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462268PMC
February 2019
1 Read

Direct detection of bacteremia by exploiting host-pathogen interactions of lipoteichoic acid and lipopolysaccharide.

Sci Rep 2019 Apr 17;9(1):6203. Epub 2019 Apr 17.

Physical Chemistry and Applied Spectroscopy, Chemistry Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States.

Bacteremia is a leading cause of death in sub-Saharan Africa where childhood mortality rates are the highest in the world. The early diagnosis of bacteremia and initiation of treatment saves lives, especially in high-disease burden areas. However, diagnosing bacteremia is challenging for clinicians, especially in children presenting with co-infections such as malaria and HIV. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-42502-5DOI Listing

Rapid screening of engineered microbial therapies in a 3D multicellular model.

Proc Natl Acad Sci U S A 2019 Apr 17. Epub 2019 Apr 17.

Department of Biomedical Engineering, Columbia University, New York, NY 10027;

Synthetic biology is transforming therapeutic paradigms by engineering living cells and microbes to intelligently sense and respond to diseases including inflammation, infections, metabolic disorders, and cancer. However, the ability to rapidly engineer new therapies far outpaces the throughput of animal-based testing regimes, creating a major bottleneck for clinical translation. In vitro approaches to address this challenge have been limited in scalability and broad applicability. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1820824116DOI Listing
April 2019
1 Read

A Live Vaccine Delivering PcrV through the Type III Secretion System Protects against Pseudomonas aeruginosa.

mSphere 2019 Apr 17;4(2). Epub 2019 Apr 17.

Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Seville, Spain

is a common Gram-negative opportunistic pathogen that is intrinsically resistant to a wide range of antibiotics. The development of a broadly protective vaccine against remains a major challenge. Here, we used an attenuated strain of serovar Typhimurium as a vehicle to express antigens. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/mSphere.00116-19DOI Listing

Risks of Practices, Procedures and Processes that Lead to Outbreaks of Foodborne Diseases.

Authors:
Frank L Bryan

J Food Prot 1988 Aug;51(8):663-673

Food Safety Consultation and Training, 2022 Lavista Circle, Tucker, Georgia 30084.

Factors that contributed to outbreaks of foodborne diseases reported in the U.S. from 1977-1982 are identified and classified by disease and place where implicated foods were mishandled. Read More

View Article

Download full-text PDF

Source
http://jfoodprotection.org/doi/abs/10.4315/0362-028X-51.8.66
Publisher Site
http://dx.doi.org/10.4315/0362-028X-51.8.663DOI Listing
August 1988
3 Reads

Prevalence and Antibiograms of Salmonellae in Slaughter Cattle, Slaughter Areas and Effluents in Zaria Abattoir, Nigeria.

J Food Prot 1989 Apr;52(4):232-235

Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria.

Mesenteric lymph nodes of slaughter cattle, swabs of slaughter and dressing areas and effluents of Zaria abattoir were cultured for salmonellae. Of a total of 510 samples cultured, 23 (5%) were positive for Salmonella . Five (4%) of 118 bovine lymph nodes contained salmonellae whereas sites swabbed during dressing had a frequency of isolation of 7% (11 of 150) and only 4 (3% of 150 samples) were positive after cleaning of dressing areas. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4315/0362-028X-52.4.232DOI Listing

Activity of 3 Commercial Bacteriophage Cocktails Against and spp. Isolates of Human Origin.

Pathog Immun 2018 29;3(1):72-81. Epub 2018 May 29.

Institute for Infectious Diseases, University of Bern, Bern, Switzerland.

Background: and spp. are 2 of the most frequent and deadly enteric bacterial pathogens recorded worldwide. In developing countries infections are responsible for many deaths annually and these mortality rates are prone to increase due to the emergence of resistance to antibiotics. Read More

View Article

Download full-text PDF

Source
https://paijournal.com/index.php/paijournal/article/view/234
Publisher Site
http://dx.doi.org/10.20411/pai.v3i1.234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423893PMC
May 2018
1 Read

Biomimetic hydroxyapatite nanocrystals are an active carrier for bacteriophages.

Int J Nanomedicine 2019 28;14:2219-2232. Epub 2019 Mar 28.

Department of Agriculture, University of Naples "Federico II", Portici, Naples, Italy,

Purpose: The use of bacteriophages represents a valid alternative to conventional antimicrobial treatments, overcoming the widespread bacterial antibiotic resistance phenomenon. In this work, we evaluated whether biomimetic hydroxyapatite (HA) nanocrystals are able to enhance some properties of bacteriophages. The final goal of this study was to demonstrate that biomimetic HA nanocrystals can be used for bacteriophage delivery in the context of bacterial infections, and contribute - at the same time - to enhance some of the biological properties of the same bacteriophages such as stability, preservation, antimicrobial activity, and so on. Read More

View Article

Download full-text PDF

Source
https://www.dovepress.com/biomimetic-hydroxyapatite-nanocrys
Publisher Site
http://dx.doi.org/10.2147/IJN.S190188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445186PMC
March 2019
2 Reads

Integrons and antibiotic resistance genes in water-borne pathogens: threat detection and risk assessment.

J Med Microbiol 2019 Apr 16. Epub 2019 Apr 16.

1 Medical Microbiology and Bioprocess Technology Laboratory, Department of Microbiology, Maharshi Dayanand University, Rohtak, Haryana 124001, India.

Antibiotic-resistant genes (ARGs) are regarded as emerging environmental pollutants and pose a serious health risk to the human population. Integrons are genetic elements that are involved in the spread of ARGs amongst bacterial species. They also act as reservoirs of these resistance traits, further contributing to the development of multi-drug resistance in several water-borne pathogens. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1099/jmm.0.000972DOI Listing

Non-typhoid Salmonella blood stream infection in Kuwait: Clinical and microbiological characteristics.

PLoS Negl Trop Dis 2019 Apr 15;13(4):e0007293. Epub 2019 Apr 15.

Department of Medicine, University of Fribourg, Switzerland.

Non-typhoid Salmonella (NTS) bacteremia is a significant cause of morbidity and mortality worldwide. It is considered to be an emerging and neglected tropical disease in Africa. We studied this in two tertiary hospitals-Al Farwaniya and Al Amiri-in Kuwait, a subtropical country, from April 2013-May 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0007293DOI Listing

New Promising Targets for Synthetic Omptin-Based Peptide Vaccine against Gram-Negative Pathogens.

Vaccines (Basel) 2019 Apr 10;7(2). Epub 2019 Apr 10.

Department of Pathology, Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.

Omptins represent a family of proteases commonly found in various Gram-negative pathogens. These proteins play an important role in host-pathogen interaction and have been recognized as key virulence factors, highlighting the possibility of developing an omptin-based broad-spectrum vaccine. The prototypical omptin, His-tagged recombinant Pla, was used as a model target antigen. Read More

View Article

Download full-text PDF

Source
https://www.mdpi.com/2076-393X/7/2/36
Publisher Site
http://dx.doi.org/10.3390/vaccines7020036DOI Listing
April 2019
5 Reads

Paediatric Salmonellosis-Differences between Tropical and Sub-Tropical Regions of Queensland, Australia.

Trop Med Infect Dis 2019 Apr 10;4(2). Epub 2019 Apr 10.

Department of Microbiology and Pathology, Townsville Hospital, Townsville 4814, Australia.

Salmonellosis is an important cause of morbidity in tropical regions.This study aims to describe the epidemiology of non-typhoidal (NTS) in children presenting to public hospitals in Queensland, Australia, over the past 20 years, with a focus on differences between tropical and sub-tropical zones in the region. This is a retrospective and descriptive cohort study of 8162 NTS positive samples collected in 0-17-year-olds from the Queensland public hospital pathology database (Auslab) over a 20-year period from 1997 to 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/tropicalmed4020061DOI Listing

Infections and pathology of free-roaming backyard chickens on St. Kitts, West Indies.

J Vet Diagn Invest 2019 Apr 11:1040638719843638. Epub 2019 Apr 11.

Departments of Biomedical Sciences (Bolfa, Callanan, Ketzis, Marchi, Cheng, Huynh, Lavinder, Boey).

Free-roaming chickens on Caribbean islands are important sentinels for local avian diseases and those introduced by birds migrating through the Americas. We studied 81 apparently healthy unvaccinated free-roaming chickens from 9 parishes on St. Kitts, an eastern Caribbean island. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1040638719843638
Publisher Site
http://dx.doi.org/10.1177/1040638719843638DOI Listing
April 2019
2 Reads

Systemic Administration of Avian Defensin 7: Distribution, Cellular Target, and Antibacterial Potential in Mice.

Front Microbiol 2019 26;10:541. Epub 2019 Mar 26.

ISP, INRA, Université de Tours, UMR 1282 Centre INRA Val de Loire, Nouzilly, France.

Defensins are natural antimicrobial peptides. The avian beta-defensin AvBD7 isolated from the chicken bone marrow possess broad antibacterial spectrum and strong resistance to proteolysis. However, its ability to fight systemic infections of major concern for public health, such as salmonellosis, is unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2019.00541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444188PMC
March 2019
1 Read

Infection-generated electric field in gut epithelium drives bidirectional migration of macrophages.

PLoS Biol 2019 Apr 9;17(4):e3000044. Epub 2019 Apr 9.

Department of Dermatology, School of Medicine, University of California, Davis, Sacramento, California, United States of America.

Many bacterial pathogens hijack macrophages to egress from the port of entry to the lymphatic drainage and/or bloodstream, causing dissemination of life-threatening infections. However, the underlying mechanisms are not well understood. Here, we report that Salmonella infection generates directional electric fields (EFs) in the follicle-associated epithelium of mouse cecum. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pbio.3000044DOI Listing
April 2019
2 Reads

paratyphi A infection presenting as breast abscess.

BMJ Case Rep 2019 Apr 8;12(4). Epub 2019 Apr 8.

Microbiology, BYL Nair Charitable Hospital, Mumbai, Maharashtra, India.

in a breast abscess is uncommon, and paratyphi A causing breast abscess is a rare entity. It has been reported post immunosuppression. We report here a 35-year-old woman with breast abscess caused by paratyphi A without obvious enteric fever-like symptoms. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2018-228887DOI Listing

Subtyping of plasmid-mediated quinolone resistance among Salmonella serotypes by whole genome sequencing.

Diagn Microbiol Infect Dis 2019 Feb 21. Epub 2019 Feb 21.

Adolfo Lutz Institute, São Paulo, Brazil. Electronic address:

Most known plasmids are identified by conferring virulence or antimicrobial resistance phenotypes and such characteristics aid in the success of the dispersion of different plasmid types between bacteria from different sources. This study aimed to perform the subtyping of the plasmid-mediated quinolone resistance, detected in Salmonella spp. A total of 34 Salmonella strains non-susceptible to ciprofloxacin were evaluated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.diagmicrobio.2019.02.015DOI Listing
February 2019

Investigation of the susceptibility trends in Japan to fluoroquinolones and other antimicrobial agents in a nationwide collection of clinical isolates: A longitudinal analysis from 1994 to 2016.

J Infect Chemother 2019 Apr 3. Epub 2019 Apr 3.

Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Japan.

The susceptibilities of clinical isolates to fluoroquinolones and other antimicrobial agents were surveyed to obtain an accurate understanding of trends in incidence and antimicrobial resistance. The samples were collected from across Japan, biennially or triennially, between 1994 and 2016 and a defined level of resistance to fluoroquinolone was determined. Streptococcus pneumoniae, Streptococcus pyogenes and Haemophilus influenzae exhibited stable and high rates of susceptibility to fluoroquinolones over the period examined. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jiac.2019.03.008DOI Listing
April 2019
1 Read

Single-Cell Metabolism and Stress Responses in Complex Host Tissues.

Authors:
Dirk Bumann

Microbiol Spectr 2019 03;7(2)

Focal Area Infection Biology, Biozentrum, University of Basel, Basel, Switzerland.

Systemic infections are a major cause of mortality worldwide and are becoming increasingly untreatable. Recent single-cell data from a mouse model of typhoid fever show that the host immune system actually eradicates many cells, while other organisms thrive at the same time in the same tissue, causing lethal disease progression. The surviving cells have highly heterogeneous metabolism, growth rates, and exposure to various stresses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/microbiolspec.BAI-0009-2019DOI Listing
March 2019
3 Reads

[Episodes of nontyphoidal salmonellosis in adult patients of the Valladolid West Area in 2017: Evaluation of the suitability of the microbiological culture request and the prescribed treatment].

Rev Esp Quimioter 2019 Apr 4. Epub 2019 Apr 4.

Mónica de Frutos, Hospital Universitario Río Hortega, Calle Dulzaina, 2 - Valladolid 47012, Spain.

Objective: Gastroenteritic salmonellosis is still the second cause diagnosed of infectious diarrhea, most of these clinical pictures are mild and self-limited and therefore the use of antibiotics is limited to few cases. The aim of the study was to describe the episodes of diarrhea caused by Salmonella enterica subsp. enterica, assessing the suitability of the request and the use of antibiotics according to the criteria included in the methodology. Read More

View Article

Download full-text PDF

Source
April 2019
3 Reads

The protective potential of selected lactic acid bacteria against the most common contaminants in various types of cheese in Egypt.

Heliyon 2019 Mar 19;5(3):e01362. Epub 2019 Mar 19.

Dairy Science Dept., (Dairy Microbiol. Lab.), National Research Centre, 33 El-Bohouth St. (Former El-Tahrir St.) Dokki, Giza, Egypt.

Dairy products, especially cheeses have a great nutritional value and a high consumption level around the world. Considering a widespread consumption of cheeses, there is a growing concern regarding safety and microbiological quality. The current study was designed to conduct a recent evaluation of cheeses microbiological quality. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S24058440183858
Publisher Site
http://dx.doi.org/10.1016/j.heliyon.2019.e01362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429812PMC
March 2019
5 Reads

Salmonella and Reactive Oxygen Species: A Love-Hate Relationship.

Authors:
Mikael Rhen

J Innate Immun 2019 Apr 3;11(3):1-11. Epub 2019 Apr 3.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden,

Salmonella enterica represents an enterobacterial species including numerous serovars that cause infections at, or initiated at, the intestinal epithelium. Many serovars also act as facultative intracellular pathogens with a tropism for phagocytic cells. These bacteria not only survive in phagocytes but also undergo de facto replication therein. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000496370DOI Listing
April 2019
3 Reads

MCR-1-producing Salmonella Typhimurium ST34 links animal foods to human community infections.

EBioMedicine 2019 Mar 30. Epub 2019 Mar 30.

Department of Pathogen Biology & Microbiology and Department of General Intensive Care Unit of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China; College of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2019.03.073DOI Listing

Rapid and Sensitive Detection of in Chickens Using Loop-Mediated Isothermal Amplification Combined with a Lateral Flow Dipstick.

J Microbiol Biotechnol 2019 Mar;29(3):454-464

College of Animal Science and Technology, Shihezi University, Shihezi 832000, P.R. China.

Salmonellosis is a highly contagious bacterial disease that threatens both human and poultry health. Tests that can detect in the field are urgently required to facilitate disease control and for epidemiological investigations. Here, we combined loop-mediated isothermal amplification (LAMP) with a chromatographic lateral flow dipstick (LFD) to rapidly and accurately detect . Read More

View Article

Download full-text PDF

Source
http://www.jmb.or.kr/journal/view.html?doi=10.4014/jmb.1712.
Publisher Site
http://dx.doi.org/10.4014/jmb.1712.12010DOI Listing
March 2019
5 Reads

Complete Genome Sequences of 20 Nontyphoidal Isolates from Rwanda.

Microbiol Resour Announc 2019 Mar 21;8(12). Epub 2019 Mar 21.

Animal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, Pennsylvania, USA.

Nontyphoidal strains are major foodborne pathogens with global public health importance. Foodborne salmonellosis can be life-threatening, especially in sub-Saharan Africa. We report the complete genome sequences of 20 nontyphoidal strains isolated in Rwanda. Read More

View Article

Download full-text PDF

Source
http://genomea.asm.org/lookup/doi/10.1128/MRA.00016-19
Publisher Site
http://dx.doi.org/10.1128/MRA.00016-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430311PMC
March 2019
2 Reads

Efficiency of Single Phage Suspensions and Phage Cocktail in the Inactivation of and Typhimurium: An Preliminary Study.

Microorganisms 2019 Mar 31;7(4). Epub 2019 Mar 31.

Department of Biology and CESAM, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal.

Enterobacteriaceae and serovar Typhimurium strains are among the main pathogens responsible for moderate and serious infections at hospital and community environments, in part because they frequently present resistance to antibiotics. As the treatment of Enterobacteriaceae infections is empiric, using the same antibiotics to treat and infections, the same concept can be applied with phages. The use of different phages combined in cocktails, frequently used to circumvent the development of phage-resistant mutants, also allows for the treatment of multiple pathogens, broadening the phages' action spectrum. Read More

View Article

Download full-text PDF

Source
https://www.mdpi.com/2076-2607/7/4/94
Publisher Site
http://dx.doi.org/10.3390/microorganisms7040094DOI Listing
March 2019
4 Reads

[Interaction of Salmonella with Macrophages-Critical Roles of Salmonella SEp22, a Pathogenicity-related Protein, and Macrophage Reactive-Oxygen Intermediate Species (ROIs) on the Infection and Survival of Salmonella].

Authors:
Fumio Amano

Yakugaku Zasshi 2019 ;139(4):617-627

Laboratory of Self-defense and Regulation, Osaka University of Pharmaceutical Sciences.

Salmonella is a Gram-negative [Gram(-)] bacteria, distributed widely in such natural environments as soil, dust, or river water, causing food poisoning as well as oral infections such as Typhi or Paratyphi. Salmonella is highly tissue invasive, easily spreading throughout the whole body after initial growth in the phagocytic vesicles of macrophages as an intra-cellular parasite. Because there remain many unknown elements in the Salmonella-macrophage interaction, I started my study by focusing on the molecules and mechanisms underlying the interaction; for example, how Salmonella escapes natural biodefense systems armed by macrophages, and how macrophages surround and inactivate Salmonella. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1248/yakushi.18-00216DOI Listing
April 2019
1 Read

Specific environmental temperature and relative humidity conditions and grafting affect the persistence and dissemination of in tomato plant tissues.

Appl Environ Microbiol 2019 Mar 29. Epub 2019 Mar 29.

Food Animal Health Research Program, Department of Veterinary Preventive Medicine, Department of Plant Pathology, The Ohio State University, OARDC, Wooster, OH.

Little is known about the abiotic factors contributing to the pre-harvest persistence of in tomato tissues. Therefore, we investigated the effects of specific environmental conditions and contamination methods on the persistence and dissemination of subsp. serotype Typhimurium (JSG626) in tomato plants. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AEM.00403-19DOI Listing
March 2019
2 Reads
3.668 Impact Factor

[What is the REAL long-term risk of proton pump inhibitors?]

Presse Med 2019 Mar 26. Epub 2019 Mar 26.

Assistance publique Hôpitaux de Paris (AP-HP), hôpital Cochin, service de gastroentérologie, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France; Université Paris-Descartes, 12, rue de l'École de médecine, 75006 Paris, France. Electronic address:

Proton pump inhibitors (PPIs) are among the most prescribed drugs in the world. While their efficacy in acute management is indisputable, it has long been suggested that PPI therapy is safe in the long term. In recent years, there has been growing and justified concern about the long-term risks of PPIs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lpm.2019.02.011DOI Listing
March 2019
1 Read

Synthetic and immunological studies of Salmonella Enteritidis O-antigen tetrasaccharides as potential anti-Salmonella vaccines.

Chem Commun (Camb) 2019 Apr;55(31):4519-4522

Departments of Chemistry and Biomedical Engineering, Institute for Quantitative Health Science & Engineering, Michigan State University, 578 South Shaw Lane, East Lansing, MI 48824, USA.

The first synthetic carbohydrate based potential anti-Salmonella Enteritidis vaccine has been developed by conjugating a synthetic tetrasaccharide antigen with bacteriophage Qβ. High levels of specific and long lasting anti-glycan IgG antibodies were induced by the conjugate, which completely protected mice from lethal bacterial challenges in a passive transfer model. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c8cc08622bDOI Listing

Shifting national surveillance of Shigella infections toward geno-serotyping by the development of a tailored Luminex assay and NGS workflow.

Microbiologyopen 2019 Mar 28:e00807. Epub 2019 Mar 28.

National Reference Centre of Salmonella and Shigella, Brussels, Belgium.

The phylogenetically closely related Shigella species and enteroinvasive Escherichia coli (EIEC) are responsible for millions of episodes of bacterial dysenteriae worldwide. Given its distinct epidemiology and public health relevance, only Shigellae are subject to mandatory reporting and follow-up by public health authorities. However, many clinical laboratories struggle to differentiate non-EIEC, EIEC, and Shigella in their current workflows, leading to inaccuracies in surveillance and rising numbers of misidentified E. Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1002/mbo3.807
Publisher Site
http://dx.doi.org/10.1002/mbo3.807DOI Listing
March 2019
4 Reads

Different Resolution Power of Multilocus Variable-Number Tandem Repeat Analysis and Whole-Genome Sequencing in the Characterization of S. 1,4,[5],12:i:- Isolates.

Foodborne Pathog Dis 2019 Mar 27. Epub 2019 Mar 27.

OIE and National Reference Laboratory for Salmonellosis, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Italy.

Salmonella enterica serovar 1,4,[5],12:i:- has emerged over the last two decades as one of the most common serovars causing human salmonellosis in Europe. It is supposed to originate from Salmonella enterica serovar Typhimurium due to antigenic and genotypic similarities between the two serovars. Due to the high level of similarity, the multilocus variable-number tandem repeat analysis (MLVA) protocol designed for Salmonella Typhimurium routine typing is commonly used also for the characterization of S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/fpd.2018.2563DOI Listing
March 2019
2.092 Impact Factor

Increased growth rate and amikacin resistance of Salmonella enteritidis after one-month spaceflight on China's Shenzhou-11 spacecraft.

Microbiologyopen 2019 Mar 25:e833. Epub 2019 Mar 25.

Nankai University School of Medicine, Tianjin, China.

China launched the Tiangong-2 space laboratory in 2016 and will eventually build a basic space station by the early 2020s. These spaceflight missions require astronauts to stay on the space station for more than 6 months, and they inevitably carry microbes into the space environment. It is known that the space environment affects microbial behavior, including growth rate, biofilm formation, virulence, drug resistance, and metabolism. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mbo3.833DOI Listing
March 2019
1 Read

Targeted interplay between bacterial pathogens and host autophagy.

Autophagy 2019 Mar 25:1-14. Epub 2019 Mar 25.

d School of Life Sciences , University of Warwick , Coventry , UK.

Due to the critical role played by autophagy in pathogen clearance, pathogens have developed diverse strategies to subvert it. Despite previous key findings of bacteria-autophagy interplay, asystems-level insight into selective targeting by the host and autophagy modulation by the pathogens is lacking. We predicted potential interactions between human autophagy proteins and effector proteins from 56 pathogenic bacterial species by identifying bacterial proteins predicted to have recognition motifs for selective autophagy receptors SQSTM1/p62, CALCOCO2/NDP52 and MAP1LC3/LC3. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15548627.2019.1590519DOI Listing

Microencapsulation of -Specific Bacteriophage Felix O1 Using Spray-Drying in a pH-Responsive Formulation and Direct Compression Tableting of Powders into a Solid Oral Dosage Form.

Pharmaceuticals (Basel) 2019 Mar 22;12(1). Epub 2019 Mar 22.

Department of Chemical Engineering, Loughborough University, Loughborough LE11 3TU, UK.

The treatment of enteric bacterial infections using oral bacteriophage therapy can be challenging since the harsh acidic stomach environment renders phages inactive during transit through the gastrointestinal tract. Solid oral dosage forms allowing site-specific gastrointestinal delivery of high doses of phages, e.g. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ph12010043DOI Listing
March 2019
1 Read

Modeling the Risk of Salmonellosis from Consumption of Peanuts in the United States.

J Food Prot 2019 Apr;82(4):579-588

3 Department of Food Science, Rutgers University, 65 Dudley Road, New Brunswick, New Jersey 08901, USA.

Peanut products were the target of the largest food recall in United States history from 2008 to 2009, with more than 3,200 products implicated, economic losses estimated at $1 billion, and more than 700 reported illnesses and 9 deaths. Predictive modeling tools such as quantitative microbial risk assessment can be used to aid processors in making risk management decisions that may reduce the chances of foodborne illness, but published risk assessment for peanuts is not currently available. A quantitative microbial risk assessment was performed to quantify salmonellosis risk from consumption of peanuts in the United States. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4315/0362-028X.JFP-18-314DOI Listing

Fluoroquinolone-Resistant Salmonella enterica, Campylobacter spp., and Arcobacter butzleri from Local and Imported Poultry Meat in Kumasi, Ghana.

Foodborne Pathog Dis 2019 Mar 23. Epub 2019 Mar 23.

1 Department Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine (BNITM), Hamburg, Germany.

Salmonella and Campylobacter are important gastroenteric pathogens. Arcobacter butzleri is an emerging enteric pathogen. Data on the frequencies of these poultry-associated pathogens on meat products sold in sub-Saharan Africa are scarce. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/fpd.2018.2562DOI Listing
March 2019
1 Read

Epidemiologic and genomic insights on mcr-1-harbouring Salmonella from diarrhoeal outpatients in Shanghai, China, 2006-2016.

EBioMedicine 2019 Mar 21. Epub 2019 Mar 21.

State Key Laboratory of Infectious Disease Prevention and Control, Beijing, China; National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China; Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing, China. Electronic address:

Background: Colistin resistance mediated by mcr-1-harbouring plasmids is an emerging threat in Enterobacteriaceae, like Salmonella. Based on its major contribution to the diarrhoea burden, the epidemic state and threat of mcr-1-harbouring Salmonella in community-acquired infections should be estimated.

Methods: This retrospective study analysed the mcr-1 gene incidence in Salmonella strains collected from a surveillance on diarrhoeal outpatients in Shanghai Municipality, China, 2006-2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2019.03.006DOI Listing
March 2019
1 Read

A proposed core genome scheme for analyses of the Salmonella genus.

Genomics 2019 Mar 21. Epub 2019 Mar 21.

Department of Zoology, University of Oxford, Peter Medawar Building for Pathogen Research, South Parks Road, Oxford OX1 3SY, United Kingdom; National Institute for Health Research, Health Protection Research Unit, Gastrointestinal Infections, University of Oxford, United Kingdom. Electronic address:

The salmonellae are found in a wide range of animal hosts and many food products for human consumption. Most cases of human disease are caused by S. enterica subspecies I; however as opportunistic pathogens the other subspecies (II-VI) and S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygeno.2019.02.016DOI Listing
March 2019
1 Read

Common Infections and Target Organs Associated with Chronic Granulomatous Disease in Iran.

Int Arch Allergy Immunol 2019 Mar 22:1-12. Epub 2019 Mar 22.

Cell and Molecular Biology Group, Airways Disease Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom,

Recurrent severe bacterial and fungal infections are characteristic features of the rare genetic immunodeficiency disorder chronic granulomatous disease (CGD). The disease usually manifests within the first years of life with an incidence of 1 in approximately 200,000 live births. The incidence is higher in Iran and Morocco where it reaches 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000496181DOI Listing
March 2019
1 Read
2.673 Impact Factor

Comparative Genomic Analyses of Municipal Wastewater Isolates Detects a Clinically Unreported Salmonellosis Outbreak.

Appl Environ Microbiol 2019 Mar 22. Epub 2019 Mar 22.

Department of Civil and Environmental Engineering, University of Hawaii at Manoa, Honolulu, HI 96822

Municipal wastewater (MW) includes human waste that contains both commensal and pathogenic enteric microorganisms, and this collective community microbiome can be monitored for community diseases. In a previous study, we assessed salmonellosis disease burden using municipal wastewater from Honolulu, Hawaii, which was monitored over a 54-week period. During this time, a serovar Paratyphi B var. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AEM.00139-19DOI Listing

Growth of Salmonella enterica Serovars Typhimurium and Enteritidis in Iron-Poor Media and in Meat: Role of Catecholate and Hydroxamate Siderophore Transporters.

J Food Prot 2019 Apr;82(4):548-560

1 Guelph Research and Development Center, Agriculture and Agri-Food Canada, 93 Stone Road West, Guelph, Ontario, Canada N1G 5C9.

Enteritidis and Typhimurium are among the top Salmonella enterica serovars implicated in human salmonellosis worldwide. This study examined the individual and combined roles of catecholate-iron and hydroxamate-iron transporters in the survival in meat of Salmonella Enteritidis and Typhimurium. Catecholate-iron-III (Fe) and hydroxamate-Fe transporter genes fepA, iroN, and fhuACDB were deleted in isolates of these serovars to generate single, double, and triple mutants. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4315/0362-028X.JFP-18-371DOI Listing
April 2019
1.849 Impact Factor

serovar enteritidis peritonitis with spontaneous intestinal perforation in an immunocompetent patient.

BMJ Case Rep 2019 Mar 20;12(3). Epub 2019 Mar 20.

Hopital d'Instruction des Armees Begin, Saint Mande, France.

Few data reported non-typhoidal peritonitis in immunocompromised patients. We reported the case of a man without immunosuppression or predisposing factor, who developed serovar Enteritidis peritonitis with spontaneous intestinal perforation. After emergent surgery, the patient was transferred to intensive care unit (ICU) because of respiratory, renal and haemodynamic failures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2018-228027DOI Listing
March 2019
1 Read

Epidemiological Survey and Retrospective Analysis of Infections between 2000 and 2017 in Warmia and Masuria Voivodship in Poland.

Medicina (Kaunas) 2019 Mar 20;55(3). Epub 2019 Mar 20.

Department of Pathophysiology, University of Warmia and Masuria, PL 10-082 Olsztyn, Poland.

: Salmonellosis is a major foodborne bacterial infection throughout the world. Epidemiological surveillance is one of the key factors to reduce the number of infections caused by this pathogen in both humans and animals. The first outcome measure was the prevalence of non-typhoid (NTS) infections between 2000 and 2017 among the population of the predominantly agricultural and touristic Polish region of Warmia and Masuria (WaM). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/medicina55030074DOI Listing
March 2019
1 Read

Evolution and transmission of a conjugative plasmid encoding both ciprofloxacin and ceftriaxone resistance in Salmonella.

Emerg Microbes Infect 2019 ;8(1):396-403

a Shenzhen Key Lab for Food Biological Safety Control, Food Safety and Technology Research Center, Hong Kong PolyU Shen Zhen Research Institute , Shenzhen , People's Republic of China.

Ceftriaxone and ciprofloxacin are the drugs of choice in treatment of invasive Salmonella infections. This study discovered a novel type of plasmid, pSa44-CIP-CRO, which was recovered from a S. London strain isolated from meat product and comprised genetic determinants that encoded resistance to both ciprofloxacin and ceftriaxone. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/22221751.2019.1585965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455229PMC
January 2019
1 Read