41,503 results match your criteria Salmonellosis


Salmonella SPI-2 type III secretion system-dependent inhibition of antigen presentation and T cell function.

Immunol Lett 2019 Feb 13. Epub 2019 Feb 13.

MRC Centre for Molecular Bacteriology and Infection, Imperial College London, SW7 2AZ, UK. Electronic address:

Salmonella enterica serovars infect a broad range of mammalian hosts, including humans, causing both gastrointestinal and systemic diseases. Effective immune responses to Salmonella infections depend largely on CD4 T cell activation by dendritic cells (DCs). Bacteria are internalised by intestinal DCs and respond by translocating effectors of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system (T3SS) into host cells. Read More

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http://dx.doi.org/10.1016/j.imlet.2019.01.006DOI Listing
February 2019

Acute epididymo-orchitis due to Salmonella Typhi in a young man from Bangladesh.

Infection 2019 Feb 15. Epub 2019 Feb 15.

Department of Infectious and Tropical Diseases, Spedali Civili, Piazzale Spedali Civili, 1, 25123, Brescia, Italy.

S. typhi infection rarely involves the genitourinary system. We report the first described case of acute epididymo-orchitis due to S. Read More

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http://dx.doi.org/10.1007/s15010-019-01280-yDOI Listing
February 2019

Integrating Typhoid Fever Within the Sustainable Development Goals: Pragmatism or Utopia?

Clin Infect Dis 2019 Feb;68(Supplement_1):S34-S41

Centre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.

Several decades following the first estimates of the global burden of typhoidal salmonellosis (infections caused by Salmonella Typhi and Salmonella Paratyphi), this disorder remains a major cause of morbidity worldwide with an estimated 17 million cases annually. The risk factors for typhoid include poverty, poor living conditions with unsafe water and lack of adequate sanitation, and unsafe foods-all reasons for the disease burden being highest among such populations including urban slums. A recent review of typhoid trends globally and in specific countries suggests that the relative contributions of these risk factors to disease burden reduction as well as persistence have varied. Read More

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http://dx.doi.org/10.1093/cid/ciy957DOI Listing
February 2019

Multidrug-resistant Nontyphoidal Salmonella Hotspots as Targets for Vaccine Use in Management of Infections in Endemic Settings.

Clin Infect Dis 2019 Feb;68(Supplement_1):S10-S15

Department of Medicine, University of Cambridge, United Kingdom.

Background: Salmonella infections cause a disproportionately high number of deaths in Africa, especially among poor urban populations. The increasing level of multidrug-resistant (MDR) infections is a major cause of concern in these settings where alternative effective treatment is unavailable. Other options for management of these infections must be sought. Read More

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http://dx.doi.org/10.1093/cid/ciy898DOI Listing
February 2019

Transcriptional Sequencing Uncovers Survival Mechanisms of Salmonella enterica Serovar Enteritidis in Antibacterial Egg White.

mSphere 2019 Feb 13;4(1). Epub 2019 Feb 13.

MOST-USDA Joint Research Center for Food Safety, School of Agriculture & Biology, and State Key Lab of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai, China

The survival mechanism of serovar Enteritidis in antibacterial egg white is not fully understood. In our lab, an egg white-resistant strain, Enteritidis SJTUF 10978, was identified. Cell envelope damage and osmotic stress response (separation of cell wall and inner membrane as well as cytoplasmic shrinkage) of this strain surviving in egg white were identified through microscopic observation. Read More

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http://dx.doi.org/10.1128/mSphere.00700-18DOI Listing
February 2019

An Unusual Case of Mycotic Popliteal Aneurysm Presenting as Recurrent Bacteraemia.

Eur J Case Rep Intern Med 2018 22;5(2):000766. Epub 2018 Feb 22.

Institute of Infectious Diseases and Epidemiology, Communicable Disease Centre, Singapore.

We describe a patient with a mycotic aneurysm. A 91-year-old man presented with recurrent episodes of bacteraemia 2 months apart. During the second presentation, he underwent magnetic resonance imaging of the left lower limb that revealed rupture of the popliteal artery with a popliteal fossa collection. Read More

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http://dx.doi.org/10.12890/2017_000766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346935PMC
February 2018

A large outbreak of Salmonella enterica Serovar Thompson Infections associated with chocolate cake in Busan, Korea.

Epidemiol Health 2019 Jan 9:e2019002. Epub 2019 Jan 9.

Division of Microbiology, Busan Institute of Health and Environment, Busan, Korea.

Objectives: This study aimed to reveal the epidemiologic characteristics of the outbreak of gastroenteritis caused by Salmonella enterica serovar Thompson in Busan Metropolitan City and to identify points for improvement to prevent of food-borne disease outbreak.

Methods: This was a case-control study. The control group comprised asymptomatic students in the same classes of the cases. Read More

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http://dx.doi.org/10.4178/epih.e2019002DOI Listing
January 2019

The high prevalence of antibiotic heteroresistance in pathogenic bacteria is mainly caused by gene amplification.

Nat Microbiol 2019 Feb 11. Epub 2019 Feb 11.

Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.

When choosing antibiotics to treat bacterial infections, it is assumed that the susceptibility of the target bacteria to an antibiotic is reflected by laboratory estimates of the minimum inhibitory concentration (MIC) needed to prevent bacterial growth. A caveat of using MIC data for this purpose is heteroresistance, the presence of a resistant subpopulation in a main population of susceptible cells. We investigated the prevalence and mechanisms of heteroresistance in 41 clinical isolates of the pathogens Escherichia coli, Salmonella enterica, Klebsiella pneumoniae and Acinetobacter baumannii against 28 different antibiotics. Read More

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http://dx.doi.org/10.1038/s41564-018-0342-0DOI Listing
February 2019

Thirty Years of Lactobacillus rhamnosus GG: A Review.

Authors:
Lucio Capurso

J Clin Gastroenterol 2019 Mar;53 Suppl 1:S1-S41

Department of Gastroenterology, San Filippo Neri Hospital, Rome, Italy.

Lactobacillus rhamnosus GG (LGG) was the first strain belonging to the genus Lactobacillus to be patented in 1989 thanks to its ability to survive and to proliferate at gastric acid pH and in medium containing bile, and to adhere to enterocytes. Furthermore LGG is able to produces both a biofilm that can mechanically protect the mucosa, and different soluble factors beneficial to the gut by enhancing intestinal crypt survival, diminishing apoptosis of the intestinal epithelium, and preserving cytoskeletal integrity. Moreover LGG thanks to its lectin-like protein 1 and 2 inhibits some pathogens such as Salmonella species. Read More

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http://dx.doi.org/10.1097/MCG.0000000000001170DOI Listing
March 2019
1 Read

Quantitative Risk Assessment Model of Human Salmonellosis Resulting from Consumption of Broiler Chicken.

Diseases 2019 Feb 7;7(1). Epub 2019 Feb 7.

Department of Biology/Environmental Science, College of Science, Engineering and Technology, Jackson State University, Jackson, MS 39217, USA.

(1) Background: infections are a major cause of illnesses in the United States. Each year around 450 people die from the disease and more than 23,000 people are hospitalized. outbreaks are commonly associated with eggs, meat and poultry. Read More

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http://dx.doi.org/10.3390/diseases7010019DOI Listing
February 2019
1 Read

[Clinical trials of salmonella enrichment medium.]

Klin Lab Diagn 2018 ;63(9):557-563

State budgetary institution of health care Infectious disease hospital, 150040 Yaroslavl, Russia.

Salmonella infections continue to be a serious problem in modern medicine. Being intestinal infections-associated pathogens, representatives of the genus Salmonella manifest themselves as pathogenic bacteria, especially in developing nosocomial infections. Given the polymorphism of clinical symptoms of salmonellosis, laboratory studies using bacteriological and serological methods are an important link in the diagnosis. Read More

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http://dx.doi.org/10.18821/0869-2084-2018-63-9-557-563DOI Listing
January 2018

Investigation of Safety Profile of Four Species and of Kaurenoic Acid by /Microsome Test.

Evid Based Complement Alternat Med 2019 10;2019:7631531. Epub 2019 Jan 10.

Laboratory of Research in Applied Microbiology (LAPEMA), University of Franca, Avenida Dr. Armando Salles de Oliveira 201, 14404-600 Franca, SP, Brazil.

Trees of the genus are native to the tropical regions of Latin America and Western Africa. sp is widely used as a popular medicine and it has various ethnopharmacological indications, including gonorrhea, bronchitis, asthma, skin ulcers, ulcers, sore throat, uterine infections, general inflammations, cancer, and leishmanioses. Kaurenoic acid is a naturally occurring diterpene found in and has been used as an anti-inflammatory, treatment of ulcer, leishmaniasis, and cancer. Read More

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http://dx.doi.org/10.1155/2019/7631531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348810PMC
January 2019
1 Read

Helicobacter pylori infection and risk of salmonella infection.

Medicine (Baltimore) 2019 Feb;98(6):e14335

Hepatology, Gastroenetrology and Infectious Diseases Department, Faculty of Medicine, Kafrelsheikh University, Kafrelsheikh.

Helicobacter pylori (H pylori) infection is the most frequent infection worldwide and it has been postulated that it predisposes to multiple enteric pathogens and diarrheal diseases. Salmonella infection is common in tropical and under developed communities and is associated with wide range of diseases from gastroenteritis to typhoid fever. This study aimed at detecting the impact of H pylori infection on the incidence of salmonella infections. Read More

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http://dx.doi.org/10.1097/MD.0000000000014335DOI Listing
February 2019
2 Reads

Characterization of the first bla/ermB-carrying IncI1 plasmid from Latin America.

Plasmid 2019 Feb 5;102:1-5. Epub 2019 Feb 5.

Departamento de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay. Electronic address:

Azithromycin represents a valid therapeutic option for gastrointestinal and systemic infections caused by multidrug resistant (MDR) diarrheagenic Escherichia coli, Shigella and Salmonella species. However, acquired macrolide resistance in these species has been increasingly described, mostly related to macrolide modifying enzymes encoded by mph- and erm-type genes. In this study, we characterized the first bla/ermB-carrying IncI1 plasmid from Latin America, which was detected in a MDR E. Read More

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http://dx.doi.org/10.1016/j.plasmid.2019.02.001DOI Listing
February 2019

Quantification and rep-PCR characterization of Salmonella spp. in retail meats and hospital patients in Northern Thailand.

Zoonoses Public Health 2019 Feb 5. Epub 2019 Feb 5.

Integrative Research Center for Veterinary Preventive Medicine, Faculty of Veterinary Medicine, Chiang Mai University, Muang, Thailand.

Human salmonellosis is a major public health problem worldwide. Infections can pass to humans by contact with contaminated substances in the food chain. This study aimed to determine the prevalence and contamination levels of Salmonella isolated from pork, chicken and beef sold in different types of retail stores in Chiang Mai and Lamphun provinces and to investigate the genetic relatedness among Salmonella isolates in food chains in that area. Read More

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http://dx.doi.org/10.1111/zph.12565DOI Listing
February 2019

Dopamine Is a Siderophore-Like Iron Chelator That Promotes Serovar Typhimurium Virulence in Mice.

MBio 2019 Feb 5;10(1). Epub 2019 Feb 5.

Department of Internal Medicine II (Infectious Diseases, Immunology, Rheumatology and Pneumology), Medical University of Innsbruck, Innsbruck, Austria

We have recently shown that the catecholamine dopamine regulates cellular iron homeostasis in macrophages. As iron is an essential nutrient for microbes, and intracellular iron availability affects the growth of intracellular bacteria, we studied whether dopamine administration impacts the course of infections. Dopamine was found to promote the growth of both in culture and within bone marrow-derived macrophages, which was dependent on increased bacterial iron acquisition. Read More

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http://dx.doi.org/10.1128/mBio.02624-18DOI Listing
February 2019
2 Reads

An economic analysis of salmonella detection in fresh produce, poultry, and eggs using whole genome sequencing technology in Canada.

Food Res Int 2019 Feb 24;116:802-809. Epub 2018 Sep 24.

Department of Agricultural Economics, McGill University, Canada.

The study estimates the annual costs of nontyphoidal Salmonellosis (referred to as Salmonellosis from hereon) from fresh produce, poultry and eggs in Canada. It also estimates the economic benefits from introduction of Whole Genome Sequencing (WGS) in detection of Salmonellosis clusters and outbreaks. Monetary and non-monetary costs from Salmonellosis are estimated. Read More

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http://dx.doi.org/10.1016/j.foodres.2018.09.014DOI Listing
February 2019

Tolerance to benzalkonium chloride and antimicrobial activity of Butia odorata Barb. Rodr. extract in Salmonella spp. isolates from food and food environments.

Food Res Int 2019 Feb 3;116:652-659. Epub 2018 Sep 3.

Departamento de Ciência e Tecnologia Agroindustrial, Faculdade de Agronomia Eliseu Maciel, Universidade Federal de Pelotas (UFPel), Pelotas, RS, Brazil; Núcleo de Biotecnologia, Centro de Desenvolvimento Tecnológico, Universidade Federal de Pelotas (UFPel), Pelotas, RS, Brazil. Electronic address:

Salmonellosis, caused by the consumption of contaminated foods, is a major health problem worldwide. The aims of this study were to assess the susceptibility of Salmonella spp. isolates to benzalkonium chloride (BC) disinfectant and the antimicrobial activity of Butia odorata Barb. Read More

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http://dx.doi.org/10.1016/j.foodres.2018.08.092DOI Listing
February 2019

Molecular, Immunological, and Clinical Features of 16 Iranian Patients with Mendelian Susceptibility to Mycobacterial Disease.

J Clin Immunol 2019 Feb 4. Epub 2019 Feb 4.

Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, 4th Floor, Building no.3, Children's Medical Center, Gharib St, Keshavarz Blvd, 14185-863, Tehran, IR, 14194, Iran.

Purpose: Mendelian susceptibility to mycobacterial disease (MSMD) is a rare primary immunodeficiency, triggered by non-tuberculous mycobacteria or Bacillus Calmette-Guérin (BCG) vaccines and characterized by severe diseases. All known genetic etiologies are inborn errors of IFN-γ-mediated immunity. Here, we report the molecular, cellular, and clinical features of patients from 15 Iranian families with disseminated disease without vaccination (2 patients) or following live BCG vaccination (14 patients). Read More

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http://link.springer.com/10.1007/s10875-019-0593-4
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http://dx.doi.org/10.1007/s10875-019-0593-4DOI Listing
February 2019
3 Reads

SLC11A1 is expressed in the human placenta across multiple gestational ages.

Placenta 2019 Jan 22;75:23-26. Epub 2018 Nov 22.

Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA. Electronic address:

The human placenta functions as an innate immune barrier to prevent fetal infection. However, the molecular mechanisms accounting for placental resistance to pathogens are currently poorly understood. The solute carrier family 11 member 1 (SLC11A1) is a divalent cation transporter expressed primarily by macrophages and neutrophils that is essential for controlling infections by intracellular pathogens such as Salmonella, Leishmania and Mycobacteria. Read More

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http://dx.doi.org/10.1016/j.placenta.2018.11.009DOI Listing
January 2019
1 Read

Rapid and specific detection of Salmonella infections using chemically modified nucleic acid probes.

Anal Chim Acta 2019 Apr 21;1054:157-166. Epub 2018 Dec 21.

Department of Physics, Chemistry and Biology, Linkӧping University, Linköping, 58185, Sweden; Wallenberg Centre for Molecular Medicine (WCMM), Linköping University, Linköping, Sweden. Electronic address:

Salmonella is a leading source of bacterial foodborne illness in humans, causing gastroenteritis outbreaks with bacteraemia occurrences that can lead to clinical complications and death. Eggs, poultry and pig products are considered as the main carriers of the pathogenic Salmonella for humans. To prevent this relevant zoonosis, key changes in food safety regulations were undertaken to improve controls in the food production chain. Read More

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http://dx.doi.org/10.1016/j.aca.2018.12.027DOI Listing
April 2019
2 Reads
4.513 Impact Factor

Antimicrobial Resistance and Presence of Cass 1 Integrons Among Different Serotypes of Salmonella spp. Recovered From Children With Diarrhea In Tehran, Iran.

Infect Disord Drug Targets 2019 Jan 30. Epub 2019 Jan 30.

Divison of Microbiology, Department of Pathobiology, School of Public Health, Tehran University of Medical Science, Tehran. Iran.

Background: Salmonellosis is a major food-borne disease worldwide. The increasing prevalence of antimicrobial resistance among food-borne pathogens such as Salmonella spp. is concerning. Read More

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http://dx.doi.org/10.2174/1871526519666190130171020DOI Listing
January 2019
1 Read

Genome analysis of Salmonella enterica subsp. diarizonae isolates from invasive human infections reveals enrichment of virulence-related functions in lineage ST1256.

BMC Genomics 2019 Jan 31;20(1):99. Epub 2019 Jan 31.

Laboratorio de Patógenos Bacterianos Intracelulares, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid, Spain.

Background: Salmonella enterica subsp. diarizonae (IIIb) is frequently isolated from the environment, cold-blooded reptiles, sheep and humans; however only a few studies describe the isolation of this subspecies from invasive human infections. The factors contributing to this unusual behavior are currently unknown. Read More

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http://dx.doi.org/10.1186/s12864-018-5352-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357384PMC
January 2019

The problem of diagnosis of generalized and focal forms of salmonellosis.

Ter Arkh 2018 Nov;90(11):90-97

Infectious Clinical Hospital №2, Moscow City Health Department, Moscow, Russia.

The article describes the clinical observation with an unfavorable outcome of the generalized form of salmonella infection caused by Salmonella typhimurium group B in a woman of 60 years without immunodeficiency, complicated by the development of multiple abscesses of the lower parts of abdominal cavity, probably of appendicular origin. In a short literary review, the pathogenetic mechanisms that contribute to the formation of generalized and extraintestinal forms of salmonella infection are discussed. Read More

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http://dx.doi.org/10.26442/terarkh2018901190-97DOI Listing
November 2018

Non-typhoidal in the Pig Production Chain: A Comprehensive Analysis of Its Impact on Human Health.

Pathogens 2019 Jan 29;8(1). Epub 2019 Jan 29.

UCIBIO@REQUIMTE, Laboratório de Microbiologia, Faculdade de Farmácia, Universidade do Porto, Portugal; Rua de Jorge Viterbo Ferreira nº 228, 4050-313 Porto, Portugal.

Salmonellosis remains one of the most frequent foodborne zoonosis, constituting a worldwide major public health concern. The most frequent sources of human infections are food products of animal origin, being pork meat one of the most relevant. Currently, particular pig food production well-adapted and persistent serotypes (e. Read More

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http://www.mdpi.com/2076-0817/8/1/19
Publisher Site
http://dx.doi.org/10.3390/pathogens8010019DOI Listing
January 2019
2 Reads

Whole-genome sequencing of the rare Salmonella enterica serovar Anfo isolated from food handlers.

J Med Microbiol 2019 Jan 30. Epub 2019 Jan 30.

3​Department of Laboratory Medicine, National University Hospital, Singapore.

Field investigations were conducted after a small cluster of food poisoning involving six cases was reported. While no stool samples were available from the cases for microbiological testing, Salmonella species was found to be present in the stools of food handlers with gastroenteritis symptoms. Four Salmonella isolates recovered from the food handlers were retrospectively investigated at the genome level using whole-genome sequencing (WGS). Read More

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http://dx.doi.org/10.1099/jmm.0.000934DOI Listing
January 2019
1 Read

Dissecting Flavivirus Biology in Salivary Gland Cultures from Fed and Unfed (Black-Legged Tick).

MBio 2019 Jan 29;10(1). Epub 2019 Jan 29.

Biology of Vector-Borne Viruses Section, Laboratory of Virology, Rocky Mountain Laboratories, NIAID/NIH, Hamilton, Montana, USA.

The tick transmits a number of pathogens, including tick-borne flaviviruses (TBFVs). In the United States, confirmed human infections with the Powassan virus (POWV) TBFV have a fatality rate of ∼10% and are increasing in incidence. Tick salivary glands (SGs) serve as an organ barrier to TBFV transmission, and little is known regarding the location of TBFV infection in SGs from fed ticks. Read More

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http://dx.doi.org/10.1128/mBio.02628-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355982PMC
January 2019

Whole genome sequencing of Chester reveals geographically distinct clusters, Norway, 2000 to 2016.

Euro Surveill 2019 Jan;24(4)

Division for Infection Control and Environmental Health, Norwegian Institute of Public Health (NIPH), Oslo, Norway.

IntroductionDuring summer 2016, Norway observed an increase in subsp. serovar Chester cases among travellers to Greece.AimOur aim was to investigate genetic relatedness of Chester for surveillance and outbreak detection by core genome multilocus sequence typing (cgMLST) and compare the results to genome mapping. Read More

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http://dx.doi.org/10.2807/1560-7917.ES.2019.24.4.1800186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352000PMC
January 2019

Evaluation of different live Salmonella Enteritidis vaccine schedules administered during layer hen rearing to reduce excretion, organ colonization, and egg contamination.

Poult Sci 2019 Jan 25. Epub 2019 Jan 25.

Departamento de Producción Animal, Instituto Nacional de Tecnología Agropecuaria (INTA), Estación Experimental Agropecuaria (EEA) Balcarce, RN 226 Km 73.3, (07620) Balcarce, Buenos Aires, Argentina.

Salmonellosis caused by Salmonella Enteritidis is a widespread zoonosis and poultry products are an important source of infection. This study was carried out to evaluate the protection of different vaccination schedules in layers using a live commercial attenuated Salmonella Enteritidis vaccine based on strain Sm24/Rif12/Ssq (AviPro® Salmonella Vac E, ELANCO) during rearing and egg production. Three hundred and fifty Salmonella-free chickens were distributed into 7 vaccinated groups and 1 unvaccinated group. Read More

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http://dx.doi.org/10.3382/ps/pez003DOI Listing
January 2019

Understanding the Relation between Establishment Food Safety Management and Salmonella Risk Factor Violations Cited during Routine Inspections.

J Food Prot 2019 Feb;82(2):339-343

2 Division of Environmental Health Sciences, School of Public Health, University of Minnesota, 420 Delaware Street S.E., Minneapolis, Minnesota 55455, USA.

Restaurants are a frequent setting for outbreaks and sporadic cases of Salmonella. The relationship among food safety management characteristics, compliance with procedures to reduce Salmonella-associated risk factors (as found during routine inspections), and the likelihood that an establishment has experienced a sporadic Salmonella case was assessed. Individual risk factor violations associated with Salmonella transmission pathways were identified by a literature review. Read More

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http://dx.doi.org/10.4315/0362-028X.JFP-18-358DOI Listing
February 2019

Correlates of non-typhoidal Salmonella bacteraemia: a case-control study.

Int J Infect Dis 2019 Jan 23. Epub 2019 Jan 23.

Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Objective: Limited up-to-date evidence exists on host-related characteristics of non-typhoidal Salmonella (NTS) bacteraemia in high-income countries. We examined correlates of non-typhoidal Salmonella (NTS) bacteraemia in Israel.

Methods: A case-control study was conducted using medical records of cases hospitalised with NTS bacteraemia (N=106; 57 children 49 adults) in Jerusalem during 1997-2016. Read More

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http://dx.doi.org/10.1016/j.ijid.2019.01.028DOI Listing
January 2019
1 Read

Assessment of Salmonella Prevalence in Lymph Nodes of U.S. and Mexican Cattle Presented for Slaughter in Texas.

J Food Prot 2019 Feb;82(2):310-315

Department of Animal Science, Texas A&M AgriLife Research, Texas A&M University, 2471 TAMU, College Station, Texas 77843-2471, USA.

Foodborne salmonellosis has been traced to undercooked ground beef and other beef products in the past, and peripheral lymph node (LN) presence in the fatty tissues of beef carcasses is one possible source of Salmonella contamination. Researchers have previously reported higher rates of Salmonella prevalence in LNs from cattle raised and harvested in Mexico compared with rates typically observed from cattle harvested in the United States. With cattle of Mexican origin comprising the majority of U. Read More

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http://dx.doi.org/10.4315/0362-028X.JFP-18-288DOI Listing
February 2019

Salmonella Contamination in Ready-to-Eat Tilapia Sashimi Processing Plants.

J Food Prot 2019 Feb;82(2):256-261

1 Zoonoses Research Center and School of Veterinary Medicine, National Taiwan University, No. 1, Section 4, Roosevelt Road, Taipei City 106, Taiwan.

In this study, we investigated contamination rates and possible contamination routes of Salmonella in two typical tilapia sashimi processing plants in Taiwan. We found that the overall isolation rate was 5.0% ( n = 61), from a total of 1,218 samples collected in a year from different processing sections (freezing, scaling and bleeding, visceral removal, washing and disinfection, and packaging) and from different operating times (before processing and 3 and 6 h after processing began). Read More

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http://dx.doi.org/10.4315/0362-028X.JFP-18-324DOI Listing
February 2019

Macrophages target Salmonella by Lc3-associated phagocytosis in a systemic infection model.

Autophagy 2019 Jan 24:1-17. Epub 2019 Jan 24.

a Institute of Biology Leiden , Leiden University , Leiden , The Netherlands.

Innate immune defense against intracellular pathogens, like Salmonella, relies heavily on the autophagy machinery of the host. This response is studied intensively in epithelial cells, the target of Salmonella during gastrointestinal infections. However, little is known of the role that autophagy plays in macrophages, the predominant carriers of this pathogen during systemic disease. Read More

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https://www.tandfonline.com/doi/full/10.1080/15548627.2019.1
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http://dx.doi.org/10.1080/15548627.2019.1569297DOI Listing
January 2019
9 Reads

Distribution of extended-spectrum β-lactamases (ESBLs) among serogroups isolated from pediatric patients.

Iran J Microbiol 2018 Oct;10(5):294-299

Department of Microbiology and Virology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.

Background And Objectives: Extended-spectrum β-lactamases (ESBLs) and fluoroquinolones are generally used to treat invasive infections, but emergence of antibiotic-resistant strains are increasing worldwide. This study was aimed to investigate the distribution of ESBLs among serogroups isolated from pediatric patients in Tehran, Iran.

Materials And Methods: The study included all isolates recovered from pediatric patients admitted to Children's Medical Center, Tehran, Iran during 2015-2016. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340002PMC
October 2018
1 Read

Older Adults and Parents of Young Children Have Different Handling Practices for Raw Poultry.

J Food Prot 2019 Feb;82(2):200-206

3 Kansas State University, 1310 Research Park Drive, Ice Hall, Manhattan, Kansas 66506, USA.

Salmonella and Campylobacter are among the most common causes of foodborne disease in the United States. Most illnesses are associated with eating raw or undercooked poultry or cross-contamination. Young children and older adults are more susceptible to contracting foodborne illness and have serious infections compared with other age groups. Read More

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http://dx.doi.org/10.4315/0362-028X.JFP-18-323DOI Listing
February 2019

Retrospective whole-genome sequencing analysis distinguished PFGE and drug-resistance-matched retail meat and clinical Salmonella isolates.

Microbiology 2019 Jan 23. Epub 2019 Jan 23.

1​Department of Food Science, The Pennsylvania State University, University Park, Pennsylvania, USA.

Non-typhoidal Salmonella is a leading cause of outbreak and sporadic-associated foodborne illnesses in the United States. These infections have been associated with a range of foods, including retail meats. Traditionally, pulsed-field gel electrophoresis (PFGE) and antibiotic susceptibility testing (AST) have been used to facilitate public health investigations of Salmonella infections. Read More

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http://dx.doi.org/10.1099/mic.0.000768DOI Listing
January 2019

Disentangling a complex nationwide Dublin outbreak associated with raw-milk cheese consumption, France, 2015 to 2016.

Euro Surveill 2019 Jan;24(3)

These authors contributed equally to this article and share last authorship.

On 18 January 2016, the French National Reference Centre for reported to Santé publique France an excess of serotype Dublin ( Dublin) infections. We investigated to identify the source of infection and implement control measures. Whole genome sequencing (WGS) and multilocus variable-number tandem repeat analysis (MLVA) were performed to identify microbiological clusters and links among cases, animal and food sources. Read More

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https://www.eurosurveillance.org/content/10.2807/1560-7917.E
Publisher Site
http://dx.doi.org/10.2807/1560-7917.ES.2019.24.3.1700703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344836PMC
January 2019
2 Reads

Comparative analysis of thymic subpopulations during different modes of atrophy identifies the reactive oxygen species scavenger, N-acetyl cysteine, to increase the survival of thymocytes during infection-induced and lipopolysaccharide-induced thymic atrophy.

Immunology 2019 Jan 19. Epub 2019 Jan 19.

Department of Biochemistry, Indian Institute of Science, Bangalore, India.

The development of immunocompetent T cells entails a complex pathway of differentiation in the thymus. Thymic atrophy occurs with ageing and during conditions such as malnutrition, infections and cancer chemotherapy. The comparative changes in thymic subsets under different modes of thymic atrophy and the mechanisms involved are not well characterized. Read More

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http://dx.doi.org/10.1111/imm.13043DOI Listing
January 2019
1 Read
3.795 Impact Factor

Beyond the antibody: B cells as a target for bacterial infection.

J Leukoc Biol 2019 Jan 18. Epub 2019 Jan 18.

Departamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Mexico.

It is well established that B cells play an important role during infections beyond antibody production. B cells produce cytokines and are APCs for T cells. Recently, it has become clear that several pathogenic bacterial genera, such as Salmonella, Brucella, Mycobacterium, Listeria, Francisella, Moraxella, and Helicobacter, have evolved mechanisms such as micropinocytosis induction, inflammasome down-regulation, inhibitory molecule expression, apoptosis induction, and anti-inflammatory cytokine secretion to manipulate B cell functions influencing immune responses. Read More

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http://doi.wiley.com/10.1002/JLB.MR0618-225R
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http://dx.doi.org/10.1002/JLB.MR0618-225RDOI Listing
January 2019
4 Reads

Prevalence, Serotypes, and Antimicrobial Resistance Profiles Among Salmonella Isolated from Food Catering Workers in Nantong, China.

Foodborne Pathog Dis 2019 Jan 18. Epub 2019 Jan 18.

2 Jiangsu Key Laboratory of Zoonosis, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.

Salmonella is a worldwide foodborne pathogen causing human disease. Food handlers, who are potential carriers of Salmonella, may transmit the pathogen to consumers through food. To determine the prevalence of Salmonella enterica serovars among food handlers working in the catering industry in Nantong, China, a total of 214,542 food handlers' fecal samples were tested for Salmonella in the Nantong CDC (Centers for Disease Control) from 2012 to 2017. Read More

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https://www.liebertpub.com/doi/10.1089/fpd.2018.2584
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http://dx.doi.org/10.1089/fpd.2018.2584DOI Listing
January 2019
2 Reads

Septic arthritis caused by Salmonella enterica serotype Rubislaw: A case report.

Rev Soc Bras Med Trop 2019 01 17;52:e20180253. Epub 2019 Jan 17.

Departamento de Pediatria, Faculdade de Ciências Médicas da Universidade Estadual de Campinas, Campinas, SP, Brasil.

An eleven-year-old boy presented with fever and hip pain, with limited mobility of the right side of the hip. Computed tomography scan revealed an increased volume of the right coxo-femoral joint, requiring surgical drainage of purulent secretion, from which Salmonella enterica was isolated. After four weeks of treatment with third-generation cephalosporin, he was discharged with a favorable evolution. Read More

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http://dx.doi.org/10.1590/0037-8682-0253-2018DOI Listing
January 2019
1 Read

Control of Salmonella Newport on cherry tomato using a cocktail of lytic bacteriophages.

Int J Food Microbiol 2019 Mar 6;293:60-71. Epub 2019 Jan 6.

Agriculture and Agrifood Canada, Guelph Research and Development Center, Guelph, Ontario N1G 5C9, Canada; Department of Food Science, University of Guelph, Guelph, ON N1G 2W1, Canada. Electronic address:

Bacteriophages have been envisioned as tools to control a variety of foodborne pathogenic bacteria. Salmonella is a foodborne pathogen that is a threat to public health around the world. Contaminated tomatoes have been associated with several Salmonella outbreaks. Read More

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http://dx.doi.org/10.1016/j.ijfoodmicro.2019.01.003DOI Listing

[Detection of serovars of Salmonella in artificially reared calves in Mar y Sierras Dairy Basin, Argentina].

Rev Argent Microbiol 2019 Jan 9. Epub 2019 Jan 9.

Departamentos de Producción Animal y de Sanidad Animal y Medicina Preventiva, Facultad de Ciencias Veterinarias UNCPBA, Tandil (Buenos Aires), Argentina.

Salmonellosis in calves is a bacterial disease that affects their digestive tract causing diarrhea. A cross-sectional epidemiological study was carried out with the aim of studying the prevalence of various serovars of Salmonella in calves and their relationship with diarrhea signs. The study was conducted in Mar and Sierras Dairy Basin located in Buenos Aires province, Argentina. Read More

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http://dx.doi.org/10.1016/j.ram.2018.09.003DOI Listing
January 2019
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Disease features of equine coronavirus and enteric salmonellosis are similar in horses.

J Vet Intern Med 2019 Jan 10. Epub 2019 Jan 10.

Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.

Background: Equine coronavirus (ECoV) is an emerging pathogen associated with fever and enteric disease in adult horses. Clinical features of ECoV infection have been described, but no study has compared these features to those of Salmonella infections.

Objectives: Compare the clinical features of ECoV infection with enteric salmonellosis and establish a disease signature to increase clinical suspicion of ECoV infection in adult horses. Read More

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http://dx.doi.org/10.1111/jvim.15386DOI Listing
January 2019

Using the wax moth larva infection model to detect emerging bacterial pathogens.

PeerJ 2019 4;6:e6150. Epub 2019 Jan 4.

European Centre for Environment and Human Health, University of Exeter, Penryn, UK.

Climate change, changing farming practices, social and demographic changes and rising levels of antibiotic resistance are likely to lead to future increases in opportunistic bacterial infections that are more difficult to treat. Uncovering the prevalence and identity of pathogenic bacteria in the environment is key to assessing transmission risks. We describe the first use of the Wax moth larva , a well-established model for the mammalian innate immune system, to selectively enrich and characterize pathogens from coastal environments in the South West of the UK. Read More

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https://peerj.com/articles/6150
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http://dx.doi.org/10.7717/peerj.6150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322482PMC
January 2019
3 Reads

Emergence of Extensively Drug-Resistant Salmonella Typhi Infections Among Travelers to or from Pakistan - United States, 2016-2018.

MMWR Morb Mortal Wkly Rep 2019 Jan 11;68(1):11-13. Epub 2019 Jan 11.

In February 2018, a typhoid fever outbreak caused by Salmonella enterica serotype Typhi (Typhi), resistant to chloramphenicol, ampicillin, trimethoprim-sulfamethoxazole, fluoroquinolones, and third-generation cephalosporins, was reported in Pakistan. During November 2016-September 2017, 339 cases of this extensively drug-resistant (XDR) Typhi strain were reported in Pakistan, mostly in Karachi and Hyderabad; one travel-associated case was also reported from the United Kingdom (1). More cases have been detected in Karachi and Hyderabad as surveillance efforts have been strengthened, with recent reports increasing the number of cases to 5,372 (2). Read More

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http://www.cdc.gov/mmwr/volumes/68/wr/mm6801a3.htm?s_cid=mm6
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http://dx.doi.org/10.15585/mmwr.mm6801a3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342547PMC
January 2019
8 Reads

Monitoring the incidence and causes of diseases potentially transmitted by food in Australia: Annual report of the OzFoodNet network, 2012.

Authors:

Commun Dis Intell (2018) 2018 16;42. Epub 2018 Nov 16.

This report summarises the incidence of diseases potentially transmitted by food in Australia and details outbreaks associated with food in 2012. OzFoodNet sites reported 27,976 notifications of diseases or conditions that may be transmitted by food. The most commonly notified infections were Campylobacter (15,668 notifications), followed by Salmonella (11,249 notifications). Read More

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November 2018

The Salmonella Enteritidis TolC outer membrane channel is essential for egg white survival.

Poult Sci 2019 Jan 9. Epub 2019 Jan 9.

Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium.

Salmonella Enteritidis has developed the potential to contaminate eggs by surviving in the antimicrobial environment of the hen's egg white. This has led to a worldwide pandemic of foodborne salmonellosis infections in humans due to the consumption of contaminated eggs and egg-derived products. The molecular mechanisms of Salmonella Enteritidis egg white survival are not fully clear. Read More

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http://dx.doi.org/10.3382/ps/pey584DOI Listing
January 2019