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Diagn Cytopathol 2020 May 26. Epub 2020 May 26.

Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.

Background: The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) is based on risk stratification. We presented our experience with fine-needle aspiration cytology (FNAC) for the diagnosis of salivary glands lesions by applying the MSRSGC categorization to the cytological diagnoses, and determined risk of malignancy (ROM) for each category.

Methods: Fine-needle aspiration cytology of salivary gland lesions performed over a 6-year period was retrieved. Read More

Acta Cytol 2020 May 19:1-7. Epub 2020 May 19.

University of Utah Health Care and ARUP Laboratories, Salt Lake City, Utah, USA.

Background: A number of guidelines have been developed to improve standardization of the terminology and criteria for cytologic specimens obtained from the thyroid, pancreas, lung, and salivary glands. A major goal of these guidelines is to improve reproducibility and understanding of the reporting of diagnostic results among cytopathologists and between cytopathologists and clinicians. The International Academy of Cytology Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy Cytopathology (IAC YSRB) is the most recent of these guidelines. Read More

Diagn Cytopathol 2020 May 18. Epub 2020 May 18.

Department of Pathology, University Hospital La Paz, Madrid, Spain.

Background: Polymorphous adenocarcinoma (PAC) is a rare malignant tumor of the minor salivary glands. It has an infiltrative growth, variable architectural patterns, neurotropism and cellular monomorphism. Approximately 75% of the cases show a specific mutation in the protein kinase D1 (PRKD1) gene. Read More

Otolaryngol Pol 2020 Feb;74(3):17-22

Klinika Otolaryngologii, Onkologii Laryngologicznej, Audiologii i Foniatrii, II Katedra Otolaryngologii, Uniwersytet Medyczny w Łodzi.

Introduction: The paper aims to demonstrate the Clinic's and own research in the treatment of major salivary gland tumors.

Material And Method: In the years 2013-2019, there were 95 salivary gland surgeries, including 45 performed in women (47.36%) aged between 24 and 82 and in 50 men (52. Read More

Ann R Coll Surg Engl 2020 May 11;102(5):340-342. Epub 2020 Mar 11.

PNS Shifa Hospital, Karachi, Pakistan.

Introduction: Fine-needle aspiration cytology (FNAC) is an important diagnostic tool used preoperatively for the diagnosis of parotid lump. Mucoepidermoid carcinoma comprises 5-10% of all salivary gland tumours. It poses a diagnostic challenge on FNAC with high false negative rate. Read More

Afr Health Sci 2019 Dec;19(4):3253-3263

Department of Restorative Dentistry, King Khalid University, Abha, Kingdom of Saudi Arabia, Pincode- 61471.

Background: Carcinoma ex pleomorphic adenoma (CA-ex-PA) is extremely unusual in minor salivary glands of oral cavity. CAex-PA is a carcinomatous change as a primary or as a recurrence of pleomorphic adenoma.

Objective: Due to resemblance of clinical symptoms of Ca ex PA and benign pleomorphic adenoma, it is mandatory for surgeons to keep high degree of clinical alertness, considering the peculiarity of this tumor. Read More

Zhonghua Bing Li Xue Za Zhi 2020 Feb;49(2):183-186

Department of Pathology, Fujian Cancer Hospital & Fujian Medical University Cancer Hospital, Fuzhou 350014, China; Department of Clinical Pathology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou 350004, China; Fujian Provincial Key Laboratory of Translational Cancer Medicine, Fuzhou 350014, China.

Cancer Cytopathol 2020 May 5;128(5):348-358. Epub 2020 Feb 5.

Department of Pathology, National University Hospital, Singapore.

Background: The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) aims to provide a common language for risk stratification and management. We examine the incidence of MSRSGC categories and the corresponding risk of malignancy (ROM) within a tertiary referral centre in Southeast Asia.

Methods: Salivary gland fine needle aspirations (FNAs) performed within a 10-year period were classified retrospectively according to the MSRSGC. Read More

Head Neck Pathol 2020 Jan 29. Epub 2020 Jan 29.

Department of Otolaryngology & Head and Neck Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Non-sebaceous lymphadenoma is a sporadic benign tumor of salivary glands. Histopathologic and immunohistochemical properties, diagnostic criteria, and theories for the histologic origin of the disease have been defined and well-discussed in the literature. However, none of the cases showed malignant transformation to date. Read More

JBI Database System Rev Implement Rep 2020 Jan 8. Epub 2020 Jan 8.

The Centre for Evidence-based Practice South Australia (CEPSA): a Joanna Briggs Institute Centre of Excellence.

Objective: The objective of this review is to determine the difference in diagnostic accuracy of core needle biopsy and fine needle aspiration for patients with a head and neck mass using surgical histopathology as a reference test. The risks and adverse events associated with each technique will also be compared.

Introduction: Tissue diagnosis is critical in evaluation of head and neck lesions to guide management. Read More

Ann Pathol 2020 Jan 6;40(1):46-58. Epub 2020 Jan 6.

Département d'anatomie et de cytologie pathologiques, institut universitaire du cancer Toulouse oncopôle, 1, avenue Irène Joliot-Curie, 31059 Toulouse cedex, France.

The salivary glands cytology is one of the most challenging area in cytopathology because of the wide diversity of benign and malignant tumors also because of their heterogeneity. However, fine needle aspiration cytology, with magnetic resonance imaging, represents a first-line examination to guide a possible surgical procedure and its extent. An accurate diagnosis of a specific tumor is sometimes difficult to assess in cytology. Read More

Rom J Morphol Embryol 2019 ;60(3):993-1002

Pathology Unit, Department of Medical and Surgical Sciences, University of Cantabria, Santander, Spain;

The occurrence of ipsilateral, synchronous, primary salivary gland tumors of different histological type is rare. In this report, we present the case of a 52-year-old male, established smoker, who showed simultaneously two different benign tumors in the right parotid gland. The patient complained of swelling below the angle of the mandible. Read More

Cancers (Basel) 2019 Dec 1;11(12). Epub 2019 Dec 1.

Department of Cytology and Pathology, Toulouse Cancer University Institute, CHU Toulouse, CEDEX, 31059 Toulouse, France.

The cytopathology of salivary glands presents major challenges due to the heterogeneity of benign and malignant neoplasms, which is reflected in the large range of WHO 2017 Classifications. Fine needle aspiration (FNA) of salivary gland tumours is still the favoured initial approach as it results in good sensitivity and specificity. The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) was published in 2018 and comprises seven categories. Read More

Otolaryngol Head Neck Surg 2020 01 3;162(1):79-86. Epub 2019 Dec 3.

Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, USA.

Objectives: To evaluate the risks of neoplasm and malignancy in surgically treated cystic parotid masses compared with solid or mixed lesions and to evaluate the performance of fine-needle aspiration (FNA) in parotid cysts.

Study Design: Retrospective cross-sectional study.

Setting: Single-institution academic tertiary care center. Read More

Case Rep Pathol 2019 17;2019:1701072. Epub 2019 Oct 17.

Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.

Pancreatic neuroendocrine neoplasms (PanNENs) are uncommon tumors. Fine needle aspiration (FNA) samples from PanNENs are typically of high cellularity and lack necrosis. In cytology slides from these tumors, dyscohesive cells are usually reported with variably round to oval to plasmacytoid forms exhibiting coarsely granular chromatin and showing immunoreactivity for synaptophysin. Read More

Diagn Cytopathol 2020 Feb 25;48(2):138-143. Epub 2019 Nov 25.

Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana.

Background: Many prior institutional and multi-institutional studies have applied the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) retrospectively to their specimens to determine the risk of malignancy (ROM) of each category. Most of these studies focused on general assessment of the system and risk classification. However, there seems to be less focus on the category of atypia of undetermined significance (AUS) that could be attributed to the low number of cases that could fit into this category. Read More

Cytopathology 2020 May 13;31(3):185-192. Epub 2020 Jan 13.

Pathology Unit, Azienda Unità Sanitaria Locale-IRCCS, Reggio Emilia, Italy.

Objective: Intraductal carcinomas (IDCs) are rare, poorly characterised salivary gland tumours. The cytological features of IDCs are even less known. In this paper, a systematic literature review of pure IDCs (without stromal invasion, not associated with other histotypes) of low-grade (LG-IDCs) and high-grade (HG-IDCs) was performed. Read More

Eur Arch Otorhinolaryngol 2020 Mar 19;277(3):841-851. Epub 2019 Nov 19.

Department of Otorhinolaryngology, San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.

Purpose: Fine needle aspiration cytology (FNAC) is a commonly performed procedure for parotid masses, although its accuracy in detecting malignancies widely varies through different series. We evaluated our single-center cohort of parotidectomies to highlight possible limitations of preoperative FNAC.

Methods: Seven hundred and eighteen consecutive patients submitted to parotid surgery at San Raffaele Scientific Institute (Milan) were retrospectively evaluated (2002-2018). Read More

Cytopathology 2020 May 25;31(3):215-222. Epub 2019 Dec 25.

Departments of Cytology, Post Graduate Institute of Medical Education& Research, Chandigarh, India.

Introduction: Adenoid cystic carcinoma (ACC) is a ubiquitous tumour which can occur in several sites of the human body. Commonly, it affects the salivary glands but also can rarely occur in various extra-salivary locations.

Aim: To study the clinical and cytological features of extra-salivary ACC on fine needle aspiration cytology. Read More

Indian J Otolaryngol Head Neck Surg 2019 Oct 6;71(Suppl 1):253-257. Epub 2018 Feb 6.

1K S Hegde Medical Academy, Nitte University, Mangalore, 575018 India.

Salivary gland diseases usually present as a swelling of the affected gland. These lesions are commonly encountered in day to day practice. A salivary gland swelling can present in a variety of locations, depending on the salivary gland affected. Read More

Am J Otolaryngol 2020 Jan - Feb;41(1):102293. Epub 2019 Sep 10.

Department of Otolaryngology-Head and Neck Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv 6423906, Israel.

Purpose: To assess the clinical value of ultrasound (US) and fine needle aspiration (FNA) of salivary gland lesions prior to surgery, for preoperative decision-making and long-term follow-up/outcome.

Materials & Methods: We retrospectively analyzed the medical charts of 98 consecutive patients with major salivary gland lesions who were treated in a single medical from 2008 to 2017. Preoperative US and FNA was performed in all patients. Read More

Diagn Cytopathol 2020 Feb 1;48(2):149-153. Epub 2019 Nov 1.

Department of Pathology and Laboratory Medicine, Kansai Medical University, Osaka, Japan.

Carcinoma ex pleomorphic adenoma (CXPA) of the salivary glands is a relatively rare carcinoma. The detection rate of the carcinoma component in the cytological specimens is not high and may be challenging in cytological examination. The purpose of the present study was to analyze the cytological specimens of CXPA with emphasis on the detection of the carcinoma component. Read More

Diagn Cytopathol 2020 Jan 30;48(1):93-95. Epub 2019 Oct 30.

Department of Pathology, Hospital de Dénia, Alicante, Spain.

Autops Case Rep 2019 Oct-Dec;9(4):e2019122. Epub 2019 Sep 30.

All India Institute of Medical Sciences, Department of Surgical Oncology. Bhubaneswar, Sijua, Orissa, India.

Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor. Although the parotid gland is the most common site of involvement, other major salivary glands and the minor salivary glands-most commonly of the palate-also can be involved. The management of mucoepidermoid carcinoma depends on the grade of the tumor and the adequacy of resection. Read More

Indian J Pathol Microbiol 2019 Oct-Dec;62(4):582-585

Department of Oral and Maxillofacial Pathology, Dharamshila Narayana Hospital, New Delhi, India.

Hepatocellular carcinoma (HCC) is the most common primary hepatic malignancy and is a leading cause of cancer-related death worldwide. It has a very aggressive clinical course, with a mean survival rate of much less than a year if left untreated. Here, we present a case of a 68-year-old male with progressively enlarging painful right facial swelling, involving the ramus and condyle of mandible on contrast-enhanced computed tomography mimicking an osteosarcoma. Read More

BMJ Case Rep 2019 Oct 8;12(10). Epub 2019 Oct 8.

Pathology Department, Gloucestershire Royal Hospital, Gloucester, UK.

A 59-year-old woman presented to an otolaryngology clinic with an 8-week history of a painless lump over her left parotid gland. Her medical history included an invasive ductal carcinoma (33 mm) and a ductal carcinoma in situ (70 mm) of the right breast, for which she had a mastectomy and various adjuvant therapies. The primary tumour presented 8 years prior to the metachronous metastasis. Read More

Diagn Cytopathol 2020 Jan 7;48(1):17-29. Epub 2019 Oct 7.

Department of Head & Neck Oncosurgery, Medanta, The Medicity, Gurgaon, India.

Background: Milan System for Reporting Salivary Gland Cytology (MSRSGC) was introduced to standardise the terminology and reporting of salivary gland cytology. The purpose of our study was to compare the conventional system and the proposed Milan System to look for concordance rates in cytohistopathologic correlation and any value addition to the conventional system.

Methods: This was a retrospective cross sectional observational study. Read More

Cancer Cytopathol 2019 Nov 25;127(11):675-679. Epub 2019 Sep 25.

Outpatient Cytopathology Center, Johnson City, Tennessee.

Arch Pathol Lab Med 2019 11 11;143(11):1338-1345. Epub 2019 Sep 11.

From the Department of Pathology and Clinical Laboratories, University of Michigan, Ann Arbor.

Context.—: Cellular basaloid neoplasms of the salivary gland represent a diverse group of benign and malignant neoplasms with significant cytomorphologic overlap on fine-needle aspiration cytology. All are marked by the presence of monotonous and usually bland basaloid epithelium. Read More

Medicine (Baltimore) 2019 Sep;98(36):e17042

Rationale: Mucosa-associated lymphoid tissue (MALT) lymphoma, also known as extranodal marginal zone B-cell lymphoma, usually occurs in the gastric mucosa, lung, lacrimal glands, and salivary glands. MALT lymphoma arising from the accessory parotid gland is extremely rare and can therefore be easily confused with other types of soft tissue masses.

Patient Concerns: A 56-year-old woman presented with a 1-month history of a mass on the left cheek. Read More

Head Neck Pathol 2020 Jun 31;14(2):525-532. Epub 2019 Aug 31.

Department of Laboratory Medicine and Pathology, University of Minnesota, 420 Delaware Street S.E. MMC 76, Minneapolis, MN, 55455, USA.

Xanthogranulomatous sialadenitis (XGS) is rare in salivary glands and only reported in the literature as single cases. Here we report a cohort of four cases with XGS and summarize the clinicopathologic features of these cases. All four patients had persistent mass lesions concerning for neoplasm. Read More

Eur Arch Otorhinolaryngol 2019 Dec 22;276(12):3461-3466. Epub 2019 Aug 22.

Department of Pathology, Osaka Medical College, Takatsuki, Osaka, Japan.

Purpose: Mammary analogue secretory carcinoma (SC) of the parotid gland is a relatively uncommon cancer associated with the ETV6-NTRK3 fusion product similar to breast cancer. The clinical characteristics and outcome of treatment were reviewed for patients with this tumor at our hospital.

Methods: In this retrospective case series, 24 patients with a diagnosis of acinic cell carcinoma (AcCC) of the parotid gland were classified as having either SC or AcCC based on analysis of the ETV6-NTRK3 fusion gene. Read More

Diagn Cytopathol 2020 Jan 21;48(1):61-65. Epub 2019 Aug 21.

Department of Pathology, SUNY Upstate Medical University, Syracuse, New York.

Epithelial-myoepithelial carcinoma (EMCa) is a rare neoplasm that most frequently afflicts the parotid gland. Histologically, a dual layer of inner, luminal epithelial cells and outer myoepithelial cells with associated background hyalinization characterize these tumors. Several variants of EMCa have been described, including the more recent description of the apocrine variant. Read More

Diagn Cytopathol 2019 Oct 8;47(10):1090-1099. Epub 2019 Aug 8.

The Leopold G. Koss Department of Cytopathology, Montefiore Medical Center/Albert Einstein College of Medicine, New York, New York.

Salivary glands located in the head and neck area are known to have different lesions with prominent oncocytic features. Fine needle aspiration is usually the initial approach in the management of these lesions, whether they represent neoplastic or non-neoplastic processes. Owing to the limited material present upon cytopathologic examination, knowledge of variants and subtypes of various oncocytic lesions that can occur in this area is of major importance to provide the most accurate interpretation to the patients and clinicians. Read More

Int J Oral Maxillofac Surg 2020 Feb 31;49(2):149-156. Epub 2019 Jul 31.

OMFS-IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, University of Leuven, Leuven, Belgium; Oral and Maxillofacial Surgery Department, University Hospitals Leuven, Leuven, Belgium.

A clinicopathological review of parotid tumours treated surgically in two oral and maxillofacial surgery departments was conducted. The performance of fine needle aspiration cytology (FNAC) was also assessed. This retrospective study included 250 consecutive patients treated surgically for parotid gland-related tumours. Read More

Indian J Pathol Microbiol 2019 Jul-Sep;62(3):379-383

Department of Otorhinolaryngology, IPGMER and SSKM Hospital, Kolkata, West Bengal, India.

Context And Background: Cytological grading of salivary gland lesion, which is a simple, cost-effective, and reproducible method, can be used as a tool for the selection of treatment modality. The proposed Milan classification establishes one guideline for reporting of salivary gland cytology and thus helps in individualized treatment and follow-up.

Aims And Objectives: (1) The aims and objectives of this study were to establish the validity and reliability of the Milan classification of cytological grading in salivary gland swelling and (2) to calculate the malignancy risk. Read More

Eur Arch Otorhinolaryngol 2019 Oct 18;276(10):2941-2946. Epub 2019 Jul 18.

Department of Otorhinolaryngology and Head and Neck Surgery, First Faculty of Medicine, Charles University, University Hospital Motol, V Uvalu 84, 150 06, Prague, Czech Republic.

Purpose: Warthin tumour (WT) is the second most common benign tumour of the parotid gland. The aim of this study was to assess the value of the FNAB in the diagnosis and treatment decision in patients with WT.

Materials And Methods: We performed a retrospective study of patients treated for parotid gland mass between 2006 and 2016. Read More

Diagn Cytopathol 2019 Nov 16;47(11):1160-1167. Epub 2019 Jul 16.

Department of Pathology and Laboratory Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.

Background: Fine needle aspiration (FNA) cytology has been widely used in the preoperative evaluation of salivary gland lesions. The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) is a tiered risk-stratification scheme designed to standardize reporting and facilitate decision making. We aimed to clarify the validity and diagnostic utility of the MSRSGC-based classification of salivary gland lesions. Read More

Diagn Cytopathol 2019 Nov 10;47(11):1125-1131. Epub 2019 Jul 10.

Department of Pathology, PGIMS, Rohtak, Haryana.

Introduction: Fine-needle aspiration cytology (FNAC) of salivary glands is a well-established technique that plays a critical role in the preoperative diagnosis of lesions. Despite its clinical utility, it remains one of the most challenging areas in cytopathology. This is because there is no consensus on how to report salivary gland cytopathology, which has resulted in inconsistent terminology and confusion in communication among cytopathologists and clinicians. Read More

Cancer Cytopathol 2019 Aug 10;127(8):529-538. Epub 2019 Jul 10.

Pathology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

Background: Salivary gland tumors are rare in pediatric patients and include both benign and malignant types. Although fine-needle aspiration cytology is widely used to diagnose salivary gland tumors in adults, such diagnostic techniques in pediatric patients are still poorly applied and studied. Nevertheless, a preoperative diagnostic definition of salivary gland lesions is highly recommended to plan a correct surgical management and to avoid over-treatment of inflammatory or reactive lesions. Read More

Eur J Pediatr 2019 Aug 1;178(8):1301-1304. Epub 2019 Jul 1.

Department of Otolaryngology, University Hospital Basel, University of Basel, 4031, Basel, Switzerland.

Sialoblastoma is a rare congenital malignant tumor of the salivary glands. A case of a submandibular sialoblastoma in a 1.5-year-old child is presented. Read More

Iran J Otorhinolaryngol 2019 May;31(104):185-190

Department of Pathology, Medanta- The Medicity, Gurugram, India .

Introduction: Pleomorphic adenomas are benign neoplasms of salivary glands. The simultaneous homolateral occurrence of these tumors in salivary glands is exceedingly rare.

Case Report: An adult female presenting to our OPD with the swelling of right-sided preauricular and submandibular regions was diagnosed with the pleomorphic adenoma based on fine needle aspiration cytology. Read More

Natl J Maxillofac Surg 2019 Jan-Jun;10(1):87-90

Department of Oral and Maxillofacial Surgery, A Coruña University Hospital, A Coruña, Spain.

Sjögren's syndrome is a chronic autoimmune disorder of the exocrine glands with associated lymphocytic infiltrates of the affected glands. Dryness of the mouth and eyes results from involvement of the salivary and lacrimal glands. Up to one-half of affected individuals also develop extraglandular involvement in organs distinct from the salivary and lacrimal glands, including the joints, skin, lung, gastrointestinal tract, nervous system, and kidneys. Read More

J Cancer Res Ther 2019 Jul-Sep;15(3):686-689

Department of Pathology, R. G. Kar Medical College and Hospital, Kolkata, West Bengal, India.

Background: Minor salivary gland tumors (MSGTs) are less common than major salivary glands and involve only 15-20% of all salivary gland tumors. Most of the cases originate at intra- and peri-oral region. Minor salivary gland lesion cytology has been studied rarely in India. Read More

Head Neck Pathol 2020 Jun 16;14(2):362-373. Epub 2019 May 16.

Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

The purpose of this study was to define the proteome profile of fine needle aspiration (FNA) samples of malignant major salivary gland tumors (MSGT) compared to benign counterparts, and to evaluate potential clinical correlations and future applications. Patients affected by MSGT (n = 20), pleomorphic adenoma (PA) (n = 37) and Warthin's tumor (WT) (n = 14) were enrolled. Demographic, clinical and histopathological data were registered for all patients. Read More

Diagn Cytopathol 2019 Sep 16;47(9):863-868. Epub 2019 May 16.

Department of Pathology, Health Sciences University, Antalya Education and Research Hospital, Antalya, Turkey.

Background: Fine-needle aspiration cytology (FNAC) is a noninvasive, safe, cost-effective, diagnostic procedure for the evaluation of salivary gland lesions and the selection of patients for surgery. The aim of this study was to analyze the risk of malignancy (ROM) according to the Milan reporting system of salivary gland FNA specimens using a liquid-based cytology (LBC) technique.

Methods: The cytological diagnosis of 459 cases between 2014 and 2017 was revised according to the Milan reporting system. Read More

Cancer Cytopathol 2019 05 3;127(5):306-315. Epub 2019 May 3.

Department of Pathology, McGill University, Montreal, Quebec, Canada.

Background: The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) is a 6-tier diagnostic category system with associated risks of malignancy (ROMs) and management recommendations. Submandibular gland fine-needle aspiration (FNA) is uncommon with a higher frequency of inflammatory lesions and a higher relative proportion of malignancy, and this may affect the ROM and subsequent management. This study evaluated the application of the MSRSGC and the ROM for each diagnostic category for 734 submandibular gland FNAs. Read More

BMJ Case Rep 2019 Apr 24;12(4). Epub 2019 Apr 24.

Oral and Maxillofacial Surgery, The Mid Yorkshire Hospitals NHS Trust, Wakefield, Yorkshire, UK.

The presence of two histologically distinct lesions within the same salivary gland is rare. The majority of lesions detected in salivary glands are benign and unifocal. Ultrasound scans and MRI imaging may not detect separate lesions that are in close proximity and this presents a challenge for radiologists and surgeons in the diagnosis of salivary gland lesions. Read More

Diagn Cytopathol 2019 Aug 25;47(8):769-775. Epub 2019 Apr 25.

Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.

Background: Fine needle aspiration cytology (FNAC) plays a pivotal role in evaluating salivary gland (SG) tumors. Several studies have shown diagnostic utility of MILAN system for reporting salivary gland cytopathology (MSRSGC) by examining risk of malignancy but only an occasional study has focused on interobserver variability. Hence, the present study was undertaken to assess the agreement among cytopathologists with varying experience in SG cytopathology using MSRSGC and to re-evaluate discordant cytohistological diagnoses for possible causes of misinterpretation. Read More

Diagn Cytopathol 2019 Aug 5;47(8):808-812. Epub 2019 Apr 5.

Department of Cytology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Adenoid cystic carcinoma (ACC) is most often primary in the major and minor salivary glands but can also arise from the submucosal seromucinous glands of the larynx and trachea. We report a case of ACC of the larynx that presented as a recurrent cough for 4 months and vomiting 3 to 4 times within 1 month. Fine-needle aspiration cytology was consistent with an ACC. Read More