960 results match your criteria Salivary Glands Fine-Needle Aspiration


Results of cystadenolymphoma treatment of superficial parotid gland.

Otolaryngol Pol 2018 Sep;72(6):23-30

Collegium Medicum Uniwersytetu Mikołaja Kopernika w Toruniu Klinika Otolaryngologii i Laryngologii Onkologicznej z Pododdziałem Audiologii i Foniatrii.

Introduction Warthin's tumor is a non-malignant tumor that occurs in major salivary glands. Diagnostics include an interview and physical examination as well as additional tests - ultrasonography, magnetic resonance tomography, fine-needle aspiration biopsy. Surgical tumor resection remains the method of treatment, the scope of which includes techniques from extracapsular tumor resection to a full range of parotidectomy. Read More

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http://dx.doi.org/10.5604/01.3001.0012.4667DOI Listing
September 2018

Salivary Gland Fine Needle Aspiration and Introduction of the Milan Reporting System.

Adv Anat Pathol 2018 Dec 28. Epub 2018 Dec 28.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

Fine needle aspiration (FNA) is a well-established procedure for the diagnosis and management of salivary gland lesions despite challenges imposed by their diversity, complexity, and cytomorphologic overlap. Until recently, the reporting of salivary gland FNA specimens was inconsistent among different institutions throughout the world, leading to diagnostic confusion among pathologists and clinicians. In 2015, an international group of pathologists initiated the development of an evidence-based tiered classification system for reporting salivary gland FNA specimens designated the "Milan System for Reporting Salivary Gland Cytopathology" (MSRSGC) that culminated with the publication of the MSRSGC Atlas in February 2018. Read More

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http://dx.doi.org/10.1097/PAP.0000000000000224DOI Listing
December 2018

Clinical analysis of false-negative fine needle aspiration cytology of head and neck cancers.

Postgrad Med 2018 Dec 17:1-5. Epub 2018 Dec 17.

a Department of Otorhinolaryngology/Head & Neck Surgery , Hamamatsu University School of Medicine , Hamamatsu , Japan.

Background: Fine-needle aspiration (FNA) cytology is frequently used for initial and/or preoperative diagnosis of tumors in the head and neck region. However, false-negative results can lead to misdiagnosis. The aim of this study was to investigate the diagnostic results of FNA in the head and neck region and the reasons for false-negative cases. Read More

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https://www.tandfonline.com/doi/full/10.1080/00325481.2019.1
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http://dx.doi.org/10.1080/00325481.2019.1559431DOI Listing
December 2018
1 Read

Mammary analogue secretory carcinoma of salivary gland diagnosed on submandibular gland cytology: A case report and review of literature.

Cytopathology 2018 Dec 1. Epub 2018 Dec 1.

Department of Pathology, University of Missouri at Kansas City, Truman Medical Center, Kansas City, Missouri, USA.

Mammary analogue secretory carcinoma (MASC) of the salivary glands morphologic and molecular similarities to secretory carcinoma of the breast(sc). (1) Here, we report a 46 year old female who presented with a right submandibular gland mass. Fine needle aspiration differential diagnosis included oncocytosis, oncocytoma, acinic cell carcinoma and MASC. Read More

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http://dx.doi.org/10.1111/cyt.12666DOI Listing
December 2018
1 Read

Accuracy of fine-needle aspiration cytology of head and neck masses.

Diagn Cytopathol 2018 Nov 29. Epub 2018 Nov 29.

Faculté de Médecine de Tunis, Université de Tunis El Manar, UR17ES15, Tunis, Tunisie.

Background: Head and neck masses are a common presentation in daily practice and can be challenging to both clinicians and cytopathologists. Fine needle aspiration cytology (FNAC) is a widely used method for the diagnosis of head and neck masses. The aim of the study was to assess our institutional experience of the accuracy of FNAC in the diagnosis of head and neck masses. Read More

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http://dx.doi.org/10.1002/dc.24120DOI Listing
November 2018
7 Reads

Retrospective assessment of the effectiveness of the Milan system for reporting salivary gland cytology: A systematic review and meta-analysis of published literature.

Diagn Cytopathol 2019 Feb 29;47(2):67-87. Epub 2018 Oct 29.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, University of Pennsylvania, Philadelphia, Pennsylvania.

Introduction: Fine needle aspiration (FNA) has been widely utilized in establishing the nature of salivary gland lesions and guiding the clinical management. This study aimed to determine the accuracy of FNA in detecting salivary gland neoplasms and malignancies, employing the "Milan System for Reporting Salivary Gland Cytopathology" (MSRSGC).

Method: A systematic search was conducted. Read More

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http://doi.wiley.com/10.1002/dc.24097
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http://dx.doi.org/10.1002/dc.24097DOI Listing
February 2019
1 Read

Diagnostic Accuracy of Fine Needle Aspiration Cytology in Lesions of Oral Cavity and Salivary Glands: A Clinico-Pathological Study.

Open Dent J 2018 28;12:782-790. Epub 2018 Sep 28.

Department of Pathology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, India.

Objective: Fine Needle Aspiration Cytology (FNAC) is a rapid, reliable and safe diagnostic tool used for various lesions of the oral cavity and salivary glands. The present study was undertaken to categorize the cytomorphology of the oral cavity and salivary gland lesions on FNAC and to assess the accuracy of FNAC in arriving at a diagnosis.

Materials And Methods: A prospective study on oral cavity swellings and salivary gland aspirates was done during a 2 year period from August 2015 to July 2017 in which a total of 70 FNAC's were performed. Read More

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http://benthamopen.com/FULLTEXT/TODENTJ-12-782
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http://dx.doi.org/10.2174/1745017901814010782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182874PMC
September 2018
17 Reads

A comparison study of the reporting systems for salivary gland fine needle aspirations: Are they really different?

Diagn Cytopathol 2018 Oct;46(10):859-863

Unit of Molecular Pathology, IPATIMUP, Institute of Molecular Pathology and Immunology of University of Porto, Porto, Portugal.

Background: Recently a new system for reporting salivary gland fine-needle aspiration (FNA) cytology was proposed, the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC). Herein, we evaluated diagnostic accuracy of salivary gland FNA, comparing the system previously used in our hospital with the Milan system.

Methods: Salivary gland specimens obtained between 2011 and 2017 were reclassified according to MSRSGC. Read More

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http://doi.wiley.com/10.1002/dc.24037
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http://dx.doi.org/10.1002/dc.24037DOI Listing
October 2018
12 Reads

Adenoid cystic carcinoma: A study of 19 cases of salivary and extra-salivary tumours diagnosed by fine needle aspiration cytology.

Diagn Cytopathol 2018 Dec 3;46(12):1004-1009. Epub 2018 Oct 3.

Department of Pulmonary Medicine, Government Medical College and Hospital, Chandigarh, India.

Background: Adenoid cystic carcinoma (ACC) arises at sites where seromucinous or sweat gland epithelium is present and commonly affects the salivary glands. Rarely it can occur at extra-salivary locations.

Methods: A retrospective analysis of 19 cases of ACC diagnosed on fine needle aspiration cytology (FNAC) over a period of 15 y (2002-2016) was made. Read More

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http://doi.wiley.com/10.1002/dc.24075
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http://dx.doi.org/10.1002/dc.24075DOI Listing
December 2018
10 Reads

Preoperative diagnostic of parotid gland neoplasms: fine-needle aspiration cytology or core needle biopsy?

Eur Arch Otorhinolaryngol 2018 Nov 20;275(11):2609-2613. Epub 2018 Sep 20.

International Head and Neck Scientific Group, Padua, Italy.

A preoperative cytologic or histologic diagnosis of parotid gland neoplasms is mandatory to decide which surgical procedure would be appropriate. Open biopsies are contraindicated because of the risk of recurrence secondary to tumour cell seeding; furthermore a subsequent curative parotid surgery can be complicated by a previous open biopsy. While fine-needle aspiration cytology (FNAC) was the only preoperative diagnostic procedure to distinguish benign versus malignant neoplasms over the past decades, core needle biopsy (CNB) has been increasingly used over the last few years. Read More

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http://dx.doi.org/10.1007/s00405-018-5131-0DOI Listing
November 2018

Application of the Milan System for Risk Stratification and Its Comparison with a Previous Reporting System of Parotid Gland Cytopathology in a Tertiary Care Centre.

Acta Cytol 2018 17;62(5-6):352-359. Epub 2018 Sep 17.

Objective: To compare the recently proposed Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) with the four-tiered reporting system (FTRS) followed at our institute.

Methods: Parotid gland fine-needle aspirates reported over a period of 5 years were analysed. These aspirates had been placed into 4 categories according to the FTRS: unsatisfactory (UNS), no evidence of malignancy/negative (NEG), inconclusive for malignancy (INC), and diagnostic for malignancy/positive (POS). Read More

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http://dx.doi.org/10.1159/000492051DOI Listing
January 2019

Updates in Salivary Gland Fine Needle Aspiration Biopsy: The Use of the Milan System and Ancillary Testing.

Authors:
Edward B Stelow

Surg Pathol Clin 2018 Sep;11(3):489-500

Department of Pathology, UVA Hospital, University of Virginia, MC 800214, Jefferson Park Avenue, Charlottesville, VA 22908, USA. Electronic address:

Salivary gland fine needle aspiration biopsies remain common specimens seen by most cytology services. The diagnostic diversity and overlap between many of the lesions seen with these biopsies impart many challenges for the cytopathologist, rendering most specific diagnoses impossible with cytology alone. Here, the use of the Milan System for the classification of salivary gland fine needle aspiration biopsy FNAB is discussed, together with the potential use of ancillary testing in arriving at definitive diagnoses. Read More

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http://dx.doi.org/10.1016/j.path.2018.04.003DOI Listing
September 2018

Unicystic high-grade intraductal carcinoma of the parotid gland: cytological and histological description with clinic-pathologic review of the literature.

APMIS 2018 Sep;126(9):771-776

Laboratory of Pathology, Department of Translational Medicine, UPO School of Medicine, Novara, Italy.

Intraductal carcinoma of the salivary glands is a rare, not well-characterized tumor. We reviewed the literature and report the first case of a high-grade unicystic intraductal carcinoma of the parotid. Formalin-fixed/paraffin-embedded blocks were sectioned and stained for hematoxylin and eosin and immunostains (CAM5. Read More

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http://doi.wiley.com/10.1111/apm.12882
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http://dx.doi.org/10.1111/apm.12882DOI Listing
September 2018
10 Reads

Cytopathological findings of proliferating pilomatricoma misdiagnosed as a malignant parotid gland tumor.

Diagn Pathol 2018 Aug 28;13(1):65. Epub 2018 Aug 28.

Department of Pathology and Laboratory Medicine, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa, 920-0293, Japan.

Background: Pilomatricoma is a relatively common benign cutaneous adnexal neoplasm with differentiation towards the hair matrix, inner sheath of hair follicle and hair cortex. Proliferating pilomatricoma is a rare variant of pilomatricoma that can rapidly increase and may be misidentified as a malignant tumor. We herein report the cytopathological findings of proliferating pilomatricoma misdiagnosed as a malignant parotid tumor. Read More

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https://diagnosticpathology.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13000-018-0738-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114043PMC
August 2018
4 Reads

Potential Difficulties in Cytological Approach of Basal Cell Adenoma of Salivary Glands: The Experience of a Single Institution.

Acta Cytol 2018 25;62(5-6):346-351. Epub 2018 Jul 25.

Objective: Basal cell adenoma (BCA) is an uncommon benign epithelial neoplasm of salivary glands, which was first described by Kleinsasser and Klein in 1967 and which derives its name from the monomorphic basaloid appearance of tumor cells. This tumor represents 1-2% of all salivary gland epithelial tumors; the most common site of occurrence is the parotid gland. It usually arises in adults over 50 years of age with slight female prevalence. Read More

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http://dx.doi.org/10.1159/000490692DOI Listing
January 2019
10 Reads

Adult Cystic Lymphangioma of the Parotid Gland: An Unwonted Presentation.

Cureus 2018 May 18;10(5):e2644. Epub 2018 May 18.

General Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, IND.

Cystic lymphangioma of the parotid gland is an uncommon congenital lymphatic malformation. Its occurrence in patients of advanced age is infrequent. Patients usually present with painless soft swelling, often having experienced a long duration of symptoms. Read More

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http://dx.doi.org/10.7759/cureus.2644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051554PMC

Cystadenocarcinoma of the mandible.

Indian J Dent Res 2018 May-Jun;29(3):396-399

Department of General Pathology, Government Dental College, Kozhikode, Kerala, India.

Papillary cystadenocarcinoma of the salivary gland is a rare malignant tumor and occurs in major and minor salivary glands. Papillary cystadenocarcinoma of the mandible is exceptionally rare. It is usually a low-grade destructive tumor with a papillary and cystic architecture. Read More

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http://dx.doi.org/10.4103/ijdr.IJDR_768_16DOI Listing
December 2018
1 Read

Ectopic Salivary Gland in a Patient With Prostate Cancer at 18F-Choline PET/CT: An Incidental Finding.

Clin Nucl Med 2018 Aug;43(8):593-594

From the Nuclear Medicine and Molecular Imaging Unit, Veneto Institute of Oncology (IOV), Istituto di Ricovero e Cura a Carattere Scientifico, Padua, Italy.

A 65-year-old man with prostate cancer surgically treated in June 2016 underwent F-choline PET/CT in April 2017 for a biochemical recurrence of disease. PET/CT revealed a high tracer uptake in a solid nodulation near the left masseter muscle with a high SUVmax. The patient underwent both ultrasonography examination and fine needle aspiration cytology that confirmed the presence of an ectopic salivary gland. Read More

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http://Insights.ovid.com/crossref?an=00003072-201808000-0000
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http://dx.doi.org/10.1097/RLU.0000000000002146DOI Listing
August 2018
1 Read

[Diagnosis and treatment of basal cell adenoma of parotid gland].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Mar;32(5):341-344

Department of OtorhinolaryngologyHead and Neck Surgery, the Second Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.

To investigate the clinical features, diagnosis and treatment experience of basal cell adenoma (BCA).The clinical data of 7 patients with basal cell adenoma of the parotid gland from the Second Affiliated Hospital of Medical University of Anhui from March 2012 to June 2016 were retrospectively analyzed. Combined with literature review, the experience of diagnosis and treatment was discussed. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.05.006DOI Listing
March 2018
2 Reads

Sinonasal adenoid cystic carcinoma-role of on-site FNAC: a case report.

BMC Ear Nose Throat Disord 2018 9;18. Epub 2018 May 9.

Department of Pathology, Seth GSMC & KEMH, Parel, Mumbai, Maharashtra 4900012 India.

Background: Adenoid cystic carcinoma (ACC), a rare tumor of epithelial cell origin, commonly arises from the major salivary glands. Uncommonly it may be found outside the salivary glands and it's especially rare in the nasal cavity.

Case Presentation: A 71-year female had complaints of swelling at the base of nose, Fine needle aspiration (FNA) from the swelling revealed features of adenoid cystic carcinoma; cell block & IHC for CD-117 was positive. Read More

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https://bmcearnosethroatdisord.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12901-018-0053-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941585PMC
May 2018
3 Reads

Intraocular metastasis of medullary thyroid carcinoma investigated by transscleral fine-needle aspiration. A case report and review of the literature.

Diagn Cytopathol 2018 Sep 16;46(9):764-768. Epub 2018 Apr 16.

Department of Pathology, Institut Curie, Paris, France.

Medullary thyroid carcinoma occurs in a sporadic setting and may also be inherited in an autosomal dominant fashion, which is related with germline mutations of the RET gene. Metastases are often present at the time of a diagnosis-most frequently within the cervical lymph nodes, followed by the liver, lungs, and bones. Intraocular metastases are extremely rare. Read More

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http://doi.wiley.com/10.1002/dc.23945
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http://dx.doi.org/10.1002/dc.23945DOI Listing
September 2018
6 Reads

Partial parotidectomy under local anesthesia for benign parotid tumors - An experience of 50 cases.

Am J Otolaryngol 2018 May - Jun;39(3):286-289. Epub 2018 Mar 2.

Division of Head and Neck Surgery, Department of Surgery, United Christian Hospital, Hong Kong Special Administrative Region.

Purpose: Benign parotid tumors are adequately treated with partial parotidectomy, which is often performed under general anesthesia (GA). We have reported our preliminary results on the feasibility to perform parotidectomy under local anesthesia (LA). We hereby present our accumulated experience of partial parotidectomy under LA to further consolidate its feasibility, efficacy and safety in a larger series. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.03.008DOI Listing
October 2018
8 Reads

Diagnostic Approach to Fine Needle Aspirations of Cystic Lesions of the Salivary Gland.

Head Neck Pathol 2018 Dec 9;12(4):548-561. Epub 2018 Mar 9.

Division of Anatomic Pathology and Histology, Agostino Gemelli School of Medicine, Catholic University of Sacred Heart, Rome, Italy.

Fine needle aspiration (FNA) has diagnostic and therapeutic value in the management of salivary gland cysts. Rendering an accurate diagnosis from an aspirated salivary gland cyst is challenging because of the broad differential diagnosis, possibility of sampling error, frequent hypocellularity of specimens, morphologic heterogeneity, and overlapping cytomorphology of many cystic entities. To date, there have been no comprehensive review articles providing a practical diagnostic approach to FNA of cystic lesions of salivary glands. Read More

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http://link.springer.com/10.1007/s12105-018-0904-8
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http://dx.doi.org/10.1007/s12105-018-0904-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232202PMC
December 2018
9 Reads

Cytological investigation of a first case of basal cell adenocarcinoma arising in the minor salivary glands. Case report and review of the literature.

Diagn Cytopathol 2018 Mar 1. Epub 2018 Mar 1.

Department of Pathology, Institute Curie, Paris, France.

Basal cell adenocarcinoma (BCAC) of salivary glands is uncommon low-grade malignancy. Only 19 cases of preoperative cytology were reported up to date. We present here a new case of BCAC arising in the minor salivary gland. Read More

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http://doi.wiley.com/10.1002/dc.23919
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http://dx.doi.org/10.1002/dc.23919DOI Listing
March 2018
2 Reads

Adenoid cystic carcinoma of alveolar mucosa: A rare case report.

J Oral Maxillofac Pathol 2018 Jan;22(Suppl 1):S54-S56

Department of Conservative Dentistry and Endodontics, Goa Dental College and Hospital, Bambolim, Goa, India.

Adenoid cystic carcinomas are rare epithelial malignancies of salivary glands that show slow growth and local invasion with recurrences seen many years after diagnosis. Upto 50% of tumors occur in intraoral minor salivary glands usually in the hard palate. Tumors on the alveolar mucosa are extremely rare. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_237_13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824518PMC
January 2018

The value of fine needle aspiration cytology in the clinical management of rare salivary gland tumors.

J Appl Oral Sci 2018 22;26:e20170267. Epub 2018 Feb 22.

Mures County Emergency Clinic, Department of Oral and Maxillofacial Surgery, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania.

Salivary gland tumors are relatively rare neoplasms, mostly located in the parotid gland, and few are malignant. Preoperative evaluation of salivary gland tumors includes fine needle aspiration cytology (FNAC).

Objective: The purpose of this study was to determine the importance of FNAC in the evaluation of rare salivary gland neoplasms. Read More

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http://dx.doi.org/10.1590/1678-7757-2017-0267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829550PMC

Current usefulness of aspiration cytology (FNAC) in the head and neck diagnosis.

Pathologica 2017 Dec;109(4):355-362

Otorhinolaryngology Unit, "A. Murri" Hospital, Fermo, Italy.

Background: Fine Needle Aspiration Cytology (FNAC) is a well established and widely used method for both a preliminary and sometime final non-invasive pathologic diagnosis. FNAC is a simple and inexpensive diagnostic tool and should represent the standard of care in developing and resource-poor countries while maintaining its diagnostic usefulness in developed and advanced ones.

Methods: The concordance between preoperative FNAC and final histology was evaluated in 168 patients operated on at the Otorhinolaryngology Unit, "A. Read More

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December 2017

A review of research on cytological approach in salivary gland masses.

Indian J Dent Res 2018 Jan-Feb;29(1):93-106

Department of Oral Pathology and Microbiology, SVS Institute of Dental Sciences, Mahabubnagar, Telangana, India.

To evaluate the diagnostic accuracy of fine-needle aspirations (FNAs) in salivary gland pathologies. A comprehensive literature search was conducted in the PubMed database using related Medical Subject Heading terms "sensitivity and specificity of FNA in salivary gland" and "diagnostic accuracy of FNA in salivary gland" for the period 1980-2016, and we found that 414 research studies had been published. PRISMA technology was utilized to prepare flow chart for displaying data search strategy. Read More

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http://dx.doi.org/10.4103/ijdr.IJDR_190_17DOI Listing
September 2018

A rare primary leiomyosarcoma of the parotid gland: A case report and literature review.

Am J Otolaryngol 2018 May - Jun;39(3):345-348. Epub 2018 Feb 1.

Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai Hospital, Mount Sinai Beth Israel, 10 Union Square East, Suite 5B, New York, NY 10003, USA.

Background: Leiomyosarcoma of the head and neck region is very rare. Primary parotid leiomyosarcoma has only been reported nine times in the medical literature.

Methods: A 68-year-old female presented with a left facial mass. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.01.010DOI Listing
October 2018
5 Reads

Fine-Needle Aspiration Cytology of Carcinosarcoma in the Salivary Gland: An Extremely Rare Case Report.

J Pathol Transl Med 2018 Mar 28;52(2):136-139. Epub 2017 Dec 28.

Deparment of pathology, Gyeongsang National University Changwon Hospital, Changwon, Korea.

Carcinosarcoma of the salivary gland is an extremely rare tumor that is composed of both malignant epithelial and mesenchymal components. Diagnosing carcinosarcoma with fine-needle aspiration cytology is challenging because of its overlapping cytomorphologic characteristics with other high-grade malignant salivary gland tumors. Among the many features, including pleomorphic oncocytoid epithelial components, necrotic background, and mitoses, recognizing the singly scattered atypical spindle cells is most essential in carcinosarcoma. Read More

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http://jpatholtm.org/journal/view.php?doi=10.4132/jptm.2017.
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http://dx.doi.org/10.4132/jptm.2017.07.27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859237PMC
March 2018
5 Reads

The PRKD1 E710D hotspot mutation is highly specific in separating polymorphous adenocarcinoma of the palate from adenoid cystic carcinoma and pleomorphic adenoma on FNA.

Cancer Cytopathol 2018 Apr 20;126(4):275-281. Epub 2017 Dec 20.

Department of Pathology, Copenhagen University Hospital, Copenhagen, Denmark.

Background: Polymorphous adenocarcinoma (PAC) of the palatal minor salivary glands, previously known as polymorphous low-grade adenocarcinoma, is the second most common intraoral malignant salivary gland carcinoma after adenoid cystic carcinoma (ACC) and carries an excellent prognosis. Unfortunately, PAC demonstrates cytological overlap with 2 other salivary gland tumors frequently encountered in the same location, namely ACC and pleomorphic adenoma (PA). Recently, the protein kinase D1 (PRKD1) hotspot mutation E710D was demonstrated to be specific for PAC and to be present in the majority of cases. Read More

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http://dx.doi.org/10.1002/cncy.21959DOI Listing
April 2018
18 Reads
1 Citation
3.350 Impact Factor

The extent of surgery for benign parotid pathology and its influence on complications: A prospective cohort analysis.

Am J Otolaryngol 2018 Mar - Apr;39(2):162-166. Epub 2017 Nov 29.

Department of Otolaryngology, Head and Neck Surgery, Whangarei Base Hospital, Northland, New Zealand.

Background: The surgical management of benign parotid tumors is aimed at complete extirpation of the mass with preservation of facial nerve function. There is a relative paucity of literature pertaining to complications after benign parotid surgery and related risk factors. We aim to critically review the outcomes following treatment of benign parotid pathology when surgery entailed either complete superficial parotidectomy (CSP), partial superficial parotidectomy (PSP) or extracapsular dissection (ECD). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709173071
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http://dx.doi.org/10.1016/j.amjoto.2017.11.015DOI Listing
September 2018
6 Reads

Mucoepidermoid carcinoma mimicking a mucocele (ranula) in the floor of the mouth.

Dentomaxillofac Radiol 2018 May 10;47(4):20170331. Epub 2018 Jan 10.

1 Department of Oral Pathology, Radiology and Medicine,College of Dentistry, The University of Iowa , Iowa City, IA , USA.

Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. The submandibular gland is rarely involved, about less than 10% of all other major salivary glands. We report a case of a 49-year-old female who presented with a mass on the left side of the floor of the mouth. Read More

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http://dx.doi.org/10.1259/dmfr.20170331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991757PMC
May 2018
16 Reads

HER2/HER3-positive metastatic salivary duct carcinoma in the pleural effusion: A case report.

Diagn Cytopathol 2018 May 4;46(5):429-433. Epub 2017 Dec 4.

Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan.

Salivary duct carcinoma (SDC) is an aggressive form of salivary gland tumor, and SDC patients tend to be older men, more commonly in advanced stage with a poorer prognosis. Although the cytological characteristics of SDC on fine-needle aspiration cytology have been well-described at the primary site, they have not been explored in metastasis. Here we reported a case of HER2/HER3-positive metastatic SDC in the lung and pleural effusion. Read More

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http://dx.doi.org/10.1002/dc.23868DOI Listing
May 2018
8 Reads

Bilateral Parotid Gland Metastases from Gastric Signet-Ring Cell Carcinoma.

Tumori 2017 Nov 1:tj5000690. Epub 2017 Nov 1.

1 Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy.

Introduction Signet-ring cell (SRC) carcinoma is a common subtype of gastric adenocarcinoma associated with poor prognosis. Metastatic involvement of the parotid gland has been reported in gastric cancer patients, but never bilaterally nor in association with the SRC histotype. Here, we report the first case and a brief review of the literature. Read More

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http://dx.doi.org/10.5301/tj.5000690DOI Listing
November 2017
4 Reads

Incidental finding of upper lip Warthin tumor.

Ann Ital Chir 2017 Nov 14;6. Epub 2017 Nov 14.

Aim: This report shows an incidental finding of Warthin tumor in upper lip mucosa during hospitalization for a biting lesion of cheek mucosa MATERIALS AND METHODS: A 32-year-old male affected by a biting lesion of cheek mucosa was presented at Maxillo- Facial Unit of Federico II University. Clinical examination showed as an incidental finding a solid mass in the superficial layer of upper lip mucosa. We performed mini-invasive surgical treatment to obtain a radical excision of the cheek lesion at the same time as excision of Warthin tumor. Read More

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November 2017
8 Reads

Submandibular gland cancer: Specific features and treatment considerations.

Head Neck 2018 Jan 30;40(1):154-162. Epub 2017 Oct 30.

Department of Otorhinolaryngology - Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Background: In the absence of unified treatment protocol, we evaluated the management and outcomes of submandibular gland cancers in an unselected patient series.

Methods: We included all patients with resected submandibular gland cancer treated at the Helsinki University Hospital from 2000 to 2010 with a 5-year minimum follow-up.

Results: Twenty-five patients with cancer represented 30% of submandibular gland neoplasms, and most were adenoid cystic carcinomas (ACCs; 56%). Read More

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http://dx.doi.org/10.1002/hed.24981DOI Listing
January 2018
8 Reads

Pleomorphic Adenoma of Soft Palate: Unusual Occurrence of the Major Tumor in Minor Salivary Gland-A Case Report and Literature Review.

J Maxillofac Oral Surg 2017 Dec 8;16(4):500-505. Epub 2015 May 8.

Department of Oral and Maxillofacial Surgery, S D Dental College and Hospital, Parbhani, Maharashtra India.

Salivary gland tumours constitute about less than 4 % of all head and neck tumours. Pleomorphic adenoma, also called benign mixed tumour, is the most common tumour of the salivary glands. About 80-90 % of these tumours occur in the major salivary glands mainly parotid gland and 10 % of them occur in the minor salivary glands. Read More

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http://dx.doi.org/10.1007/s12663-015-0799-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628059PMC
December 2017
12 Reads

Adamantinoma-like Ewing sarcoma of the parotid gland: Cytopathologic findings and differential diagnosis.

Diagn Cytopathol 2018 Mar 16;46(3):263-266. Epub 2017 Oct 16.

Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21224.

Adamantinoma-like Ewing sarcoma (AES) is a rare variant of Ewing sarcoma family of tumors (EFTs), primarily affecting bone and soft tissue. AES has mixed features of Ewing sarcoma (ES)/primitive neuroectodermal tumor (PNET) and adamantinoma with a complex immunoprofile and EWSR1 gene rearrangements. Herein, we report a 72-year-old male who presented with left parotid mass, right neck mass and thyroid nodules. Read More

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http://dx.doi.org/10.1002/dc.23829DOI Listing
March 2018
7 Reads

[Cyto-histological correlation in the management of parotid gland tumors: A retrospective study of 160 cases].

Bull Cancer 2017 Oct 12;104(10):850-857. Epub 2017 Oct 12.

CHU Dupuytren, service d'ORL et de chirurgie cervicofaciale, 2, avenue Martin-Luther-King, 87000 Limoges, France.

Introduction: The aim of this study was to correlate the cytological and histological results and evaluate the diagnostic performance of fine-needle aspiration cytology (FNAC) in the management of parotid gland tumors.

Methods: This retrospective study included 160 patients with a parotid gland tumor who underwent fine-needle aspiration and parotidectomy surgery between January 2005 and August 2016 at the Limoges university hospital center.

Results: On 160 fine-needle aspirations performed, fine-needle aspiration diagnoses were: 77 benign lesions, 35 malignant lesions and 48 non-diagnostic cases. Read More

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http://dx.doi.org/10.1016/j.bulcan.2017.09.001DOI Listing
October 2017
4 Reads

Mammary Analogue Secretory Carcinoma of Parotid Gland in a Teenage Boy.

J Coll Physicians Surg Pak 2017 Sep;27(9):579-581

Department of Oncology, Atomic Energy Cancer Hospital, Nori, Islamabad.

Mammary analogue secretory carcinoma (MASC) is a rare salivary gland malignancy that exhibits resemblance with secretory carcinoma of the breast (SC) due to the presence of ETV6-NTRK3 gene fusion, formerly classified as acinic cell carcinoma. It is a slowly growing painless tumor that exhibits wide range of clinical behavior. This tumor typically affects middle aged people. Read More

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http://dx.doi.org/2706DOI Listing
September 2017

LEF-1: Diagnostic utility in distinguishing basaloid neoplasms of the salivary gland.

Diagn Cytopathol 2017 Dec 3;45(12):1078-1083. Epub 2017 Oct 3.

Emory University School of Medicine, Pathology, Atlanta, Georgia.

Background: Lymphoid enhancer binding factor 1 (LEF-1) has recently been reported as a potential immunohistochemical (IHC) marker for basal cell adenoma (BCA) and other salivary gland tumors, which may contribute to an increased accuracy in differentiating basaloid salivary gland neoplasms. We evaluated the utility of LEF-1 in fine needle aspiration (FNA) and resection specimens to distinguish pleomorphic adenoma (PA), BCA, basal cell adenocarcinoma (BCAC), and adenoid cystic carcinoma (ACC) as well as in non-neoplastic salivary gland (NNSG).

Methods: Cases including 66 PA (35 FNA, 31 resections), 12 BCA (5 FNA, 7 resections), 42 ACC (11 FNA, 31 resections), 1 BCAC FNA, and 10 NNSG (5 FNA, 5 resections) were obtained and stained for LEF-1. Read More

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http://dx.doi.org/10.1002/dc.23820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930010PMC
December 2017
13 Reads

"Atypical" salivary gland fine needle aspiration: Risk of malignancy and interinstitutional variability.

Diagn Cytopathol 2017 Dec 29;45(12):1088-1094. Epub 2017 Sep 29.

Department of Laboratory Medicine and Pathology, Temple University Hospital, Pennsylvania.

Background: Fine needle aspiration (FNA) is widely used in the diagnosis of salivary gland lesions. Salivary gland FNAs are often difficult to diagnose because of morphologic heterogeneity, a small but significant number of the FNAs yield "atypical" diagnosis. However, systematic evaluation of the risk of malignancy (ROM) of the atypical diagnoses across institutions and the variability of ROM among institutions are still lacking. Read More

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http://dx.doi.org/10.1002/dc.23826DOI Listing
December 2017
19 Reads

Cytological spectrum of salivary gland lesions and their correlation with epidemiological parameters.

J Oral Maxillofac Pathol 2017 May-Aug;21(2):203-210

Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India.

Background: The role fine-needle aspiration (FNA) in the diagnosis of salivary gland lesions has evolved over the years. Although clinical and radiological parameters help to narrow the differential diagnosis the tissue diagnosis still remains the gold standard.

Materials And Methods: This study is from January 2013 to December 2015 in our Department of Pathology where 170 salivary gland lesions were aspirated. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_61_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596669PMC
September 2017
3 Reads

A pattern-based risk-stratification scheme for salivary gland cytology: A multi-institutional, interobserver variability study to determine applicability.

Cancer Cytopathol 2017 Oct 21;125(10):776-785. Epub 2017 Aug 21.

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Background: Salivary gland aspiration cytology is useful in the preoperative management of patients but remains challenging, because of the extensive morphologic overlap of some tumors limits the ability to always determine the presence of malignancy. In response to this challenge, there has been increasing drive to develop a risk-based categorization scheme for salivary gland aspirates. Herein, the authors examine the interobserver variability of 1 such pattern and risk-based system. Read More

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http://dx.doi.org/10.1002/cncy.21906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647230PMC
October 2017
4 Reads

Three-year cytohistological correlation of salivary gland FNA cytology at a tertiary center with the application of the Milan system for risk stratification.

Cancer Cytopathol 2017 Oct 7;125(10):767-775. Epub 2017 Aug 7.

Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: Fine-needle aspiration (FNA) cytology of salivary glands is a well-established technique that plays a critical role in the preoperative diagnosis of lesions. A risk stratification of FNA diagnostic categories has been recently proposed to be useful in reporting. The aims of this study were to evaluate the diagnostic accuracy of salivary gland FNA and to apply the proposed Milan system for reporting salivary gland lesions. Read More

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http://dx.doi.org/10.1002/cncy.21900DOI Listing
October 2017
50 Reads

Utility of preoperative fine needle aspiration in parotid lesions.

Laryngoscope 2018 02 7;128(2):398-402. Epub 2017 Aug 7.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, U.S.A.

Objectives: Preoperative fine needle aspiration (FNA) of parotid lesions often is used in the initial evaluation of parotid masses, but its role in guiding surgical decision making remains unclear, in part due to varying diagnostic accuracy reported. We sought to evaluate the role of preoperative FNA in detection of malignancy and impact on surgical management.

Study Design: Retrospective study. Read More

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http://doi.wiley.com/10.1002/lary.26776
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http://dx.doi.org/10.1002/lary.26776DOI Listing
February 2018
16 Reads

Parotid gland tuberculosis.

Int J Mycobacteriol 2017 Jul-Sep;6(3):318-320

Department of Pathology, J. L. N. Medical College, Ajmer, Rajasthan, India.

This report describes parotid gland tuberculosis in a 38-year-old female patient that presented with a firm, painless, progressively increasing swelling over the right preauricular region. Diagnostic workup including contrast enhanced computerized tomography neck and subsequent fine needle aspiration cytology of the swelling made the final diagnosis. The patient responded favorably with anti-tubercular therapy. Read More

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http://dx.doi.org/10.4103/ijmy.ijmy_86_17DOI Listing
April 2018
2 Reads

Primary parotid lymphoma presenting as a recurrent cystic mass: A case report.

Laryngoscope 2018 04 3;128(4):998-1001. Epub 2017 Aug 3.

Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, Massachusetts.

A 15-year-old boy was diagnosed with a cystic parotid mass, which was initially thought to be a first branchial cleft cyst. The mass was treated with antibiotics and fully resolved on examination and imaging. The mass returned, and a superficial parotidectomy was performed to remove the suspected branchial cleft cyst. Read More

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http://dx.doi.org/10.1002/lary.26786DOI Listing
April 2018
2 Reads

Intraparotid ductal ectasia: rare cause of parotid swelling.

BMJ Case Rep 2017 Jul 27;2017. Epub 2017 Jul 27.

Department of ENT, Hopital la Rabta, Tunis, Tunisia.

A 41-year-old patient was hospitalised for a chronic right parotid mass. A cervical ultrasound revealed a cystic mass of the parotid. Cervical MRI found a ductal ectasia of the parotid and submandibular glands associated with a retention cyst of the right parotid. Read More

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http://dx.doi.org/10.1136/bcr-2017-220243DOI Listing
July 2017
13 Reads