401 results match your criteria Salivary Gland Tumors Major Benign


Endoscopic Resection of a Massive Pleomorphic Adenoma of the Nasal Septum.

Ear Nose Throat J 2021 May 31:1455613211020972. Epub 2021 May 31.

Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University, Asahikawa, Japan.

Pleomorphic adenoma is a benign tumor that commonly arises from the major salivary glands, such as the parotid and submandibular glands. However, they rarely originate from the nasal cavity. Herein, we describe the case of a 49-year-old woman who presented with nasal obstruction. Read More

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Pleomorphic adenoma of hard palate: a case report.

Pan Afr Med J 2021 9;38:146. Epub 2021 Feb 9.

Département d´Odontologie Chirurgicale, Faculté de Médecine Dentaire de Rabat, Université Mohammed V, Rabat, Maroc.

Pleomorphic adenoma is a benign mixed tumor, which is composed of myoepithelial and epithelial cells. A fibrous capsule separates these cells from the surrounding tissues. Pleomorphic adenoma is the most common salivary gland tumour accounting for 40-70% of all major and minor salivary gland tumours. Read More

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A case of a borderline adrenal oncocytoma in a 62-year old female.

Acta Chir Belg 2021 Apr 9:1-4. Epub 2021 Apr 9.

Department of Abdominal Surgery, Centre Hospitalier Bois de l'Abbaye, Seraing, Belgium.

Introduction: Adrenal oncocytomas are a rare pathology and only about 160 cases have been reported in the literature.

Case Description: We describe the case of a 62-year old female with an incidentaloma found in the right adrenal gland on a CT scan. Endocrine testing showed a non-secreting lesion. Read More

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Intraparotid Osteolipoma: Treatment Option and Surgical View.

J Craniofac Surg 2021 Feb 2. Epub 2021 Feb 2.

Maxillofacial Surgery Unit, Policlinico San Marco University Hospital, University of Catania, Catania Division of Otorhinolaryngology, Department of Surgery, Dentistry, Gynecology and Pediatrics, University of Verona, Borgo Trento Hospital of Verona, Verona Anatomical Pathology Unit, Policlinico San Marco University Hospital, University of Catania, Catania, Italy.

Abstract: Osteolipoma is a benign neoplasm originating from the mesenchymal fat tissue cells and characterized by the presence of bone formation. In the head and neck district osteolipoma has been described as parapharyngeal, nasopharinx, submandibular gland, eyelid, floor of the mouth, and skull base lesion. Only 1 case of osteolipoma was reported as a neoplasm of the parotid region. Read More

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February 2021

Oncocytic mucoepidermoid carcinoma (OMEC) of the parotid gland in a 12-year-old patient: A diagnostic challenge on cytology.

Diagn Cytopathol 2021 Feb 15;49(2):E60-E64. Epub 2020 Aug 15.

Department of Pathology, King George's Medical University, Lucknow, India.

Mucoepidermoid carcinoma is the most common malignant salivary gland neoplasm comprising approximately 10% of all tumours of the major salivary gland. Owing to a plethora of morphological variations, it poses a diagnostic challenge on fine-needle aspiration cytology. Oncocytic variant of mucoepidermoid carcinoma is a rare subtype seen in the age group of 20-80 years. Read More

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February 2021

Functional outcomes after extracapsular dissection with partial facial nerve dissection for small and large parotid neoplasms.

Am J Otolaryngol 2021 Jan - Feb;42(1):102770. Epub 2020 Oct 22.

Department of Otorhinolaryngology - Head and Neck Surgery, Rush University Medical Center, Chicago, IL, USA. Electronic address:

Purpose: Multiple surgical options exist for benign parotid tumors without agreement upon a single, best approach. We evaluated the short-term outcomes and rate of complications using the ECD-FND technique for small and large parotid neoplasms involving the superficial and deep lobes of the parotid gland using a categorical approach.

Material And Methods: A single surgeon retrospective cohort study with analysis of patient demographics, outcomes, and complication rates was conducted of patients undergoing the ECD-FND for benign parotid neoplasm. Read More

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October 2020

Surgical Treatment of Brooke-Spiegler Syndrome.

J Craniofac Surg 2020 Nov 10. Epub 2020 Nov 10.

Division of Hand- and Plastic Surgery.

Brooke-Spiegler Syndrome (BSS) is a very rare autosomal dominant hereditary disease which arises from heterozygous mutations in the CYLD gene. Patients with BSS are predisposed to multiple skin appendage tumors such as cylindromas, which are benign tumors occurring mainly on the scalp. The tumors mostly appear around puberty and usually show slow growth throughout life. Read More

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November 2020

Atypical localisation of pleomorphic adenoma issue from heterotopic salivary tissue in the supraclavicular region: diagnosis and management.

BMJ Case Rep 2020 Nov 2;13(11). Epub 2020 Nov 2.

Pathology, Sion Hospital Valais Romand Hospital Center, Sion, Valais, Switzerland.

Heterotopic salivary tissue (HST) is a normal salivary tissue located outsides the major and minor salivary glands. Multiple sites of localisation of heterotopias have been described, the occurrence of HST in the neck is rare and it may have several clinical manifestation. We report the case of 72-year-old Caucasian man presenting a suspect mass on the left-sided supraclavicular region. Read More

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November 2020

The role of fine needle aspiration biopsy in deep lobe parotid tumors: Comparison of preoperative cytology and postoperative histopathologic results.

Am J Otolaryngol 2021 Jan - Feb;42(1):102590. Epub 2020 Jun 10.

Sisli Hamidiye Etfal Training and Research Hospital, Department of Ear Nose Throat Head and Neck Surgery, Istanbul, Turkey.

Purpose: Major salivary gland tumors constitute almost 3% of head and neck tumors. Tumors located exclusively in the deep lobe are not common and 20% of parotid gland tumors originate from deep lobe under the branches of the facial nerve. Accuracy of fine needle aspiration biopsy (FNAB) procedure in salivary gland tumors have been studied extensively, however there isn't any data regarding usefulness of FNAB in tumors located exclusively in deep lobe of parotid gland. Read More

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Salivary Gland Tumors: A Retrospective Study of 164 Cases from a Single Private Practice Service in Mexico and Literature Review.

Head Neck Pathol 2021 Jun 12;15(2):523-531. Epub 2020 Oct 12.

Facultad de Odontología, Universidad Autónoma Metropolitana Xochimilco (UAM), México City, México.

Salivary gland tumors (SGT) represent an uncommon heterogeneous group of tumors with complex clinical and pathological characteristics. The prevalence of these lesions varies between studies but has been estimated between 3 and 6% of all tumors in the head and neck region. The present study aimed to evaluate the distribution and demographic findings of salivary gland tumors diagnosed in an oral pathology service in Mexico. Read More

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Salivary gland neoplasms: A 10-year review of a major referral center in Ghana.

Oral Surg Oral Med Oral Pathol Oral Radiol 2021 Feb 18;131(2):161-165. Epub 2020 Aug 18.

Department of Community and Preventive Dentistry, University of Ghana Dental School, College of Health Sciences, University of Ghana, Accra, Ghana.

Objective: The aim of this study was to describe the clinicopathologic features of salivary gland tumors (SGTs) that were managed at a major referral center in Ghana.

Study Design: This was a retrospective study of all histologically diagnosed and managed Ghanaian patients with SGTs during the period January 2008 to December 2017. Information collected included age, gender, affected gland, presenting symptom, treatment modality, histologic diagnosis, and complications. Read More

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February 2021

Individualized Use of Facelift, Retroauricular Hairline, and V-Shaped Incisions for Parotidectomy.

J Oral Maxillofac Surg 2020 12 26;78(12):2339.e1-2339.e8. Epub 2020 Aug 26.

Professor & Department Head, Department of Otolaryngology-Head and Neck Surgery, Kyungpook National University, Daegu, Korea.

Purpose: Despite the increased need for better cosmetic outcomes following parotidectomy, there is no study on the individualized use of esthetic approaches for parotidectomy. We aimed to evaluate the feasibility of individualzsed esthetic approaches for parotidectomy using facelift (FL), retroauricular hairline (RAH), and V-shaped incisions, and compare their surgical and cosmetic outcomes.

Methods: This was a retrospective cohort study. Read More

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December 2020

Transoral robotic surgery in head and neck district: a retrospective study on 67 patients treated in a single center.

Infect Agent Cancer 2020 15;15:40. Epub 2020 Jun 15.

Maxillofacial & ENT surgery Unit, Istituto Nazionale Tumori-IRCCS "Fondazione G. Pascale", via M. Semmola, Naples, Italy.

Background: The anatomical complexity of the oropharynx and the difficulty in reaching its distal portion have always conditioned the surgical accessibility.Robotic surgery represents an excellent alternative in the treatment of cervico-facial oncological diseases.

Methods: This series comprises all patients managed for head and neck cancer by Trans Oral Robotic Surgery TORS. Read More

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Giant submandibular sialolipoma masquerading as huge goitre: a case report.

BMC Surg 2020 Jun 11;20(1):130. Epub 2020 Jun 11.

Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia.

Background: Sialolipoma is a rare tumour which may arise from both major and minor salivary glands and has recently been described as a variant of salivary gland lipomatous lesions.

Case Presentation: We report a 54-year-old male who presented with a 7-year history of large right anterior neck swelling. He was clinically euthyroid and had no compressive or infiltrative symptoms. Read More

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Own experience in the treatment of major salivary gland tumors.

Otolaryngol Pol 2020 Feb;74(3):17-22

Klinika Otolaryngologii, Onkologii Laryngologicznej, Audiologii i Foniatrii, II Katedra Otolaryngologii, Uniwersytet Medyczny w Łodzi.

Introduction: The paper aims to demonstrate the Clinic's and own research in the treatment of major salivary gland tumors.

Material And Method: In the years 2013-2019, there were 95 salivary gland surgeries, including 45 performed in women (47.36%) aged between 24 and 82 and in 50 men (52. Read More

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February 2020

Epidemiologic analysis of salivary gland tumors over a 10-years period diagnosed in a northeast Brazilian population.

Med Oral Patol Oral Cir Bucal 2020 Jul 1;25(4):e516-e522. Epub 2020 Jul 1.

Laboratory of Morphology and Experimental Pathology Institute of Technology and Research, Tiradentes University Av. Murilo Dantas, 300, Farolândia, Aracaju, SE 49032-490, Brazil

Background: Salivary gland tumors (SGT) correspond to a heterogeneous group of lesions with variable biological behavior. The present study aimed to determine the distribution and demographic findings of salivary gland neoplasms in a northeast Brazilian population.

Material And Methods: A retrospective descriptive cross-sectional study was performed. Read More

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Cosmetic approach selection in parotidectomy for benign parotid gland tumour according to its location.

J Plast Reconstr Aesthet Surg 2020 May 11;73(5):921-926. Epub 2019 Oct 11.

Department of Oral & Maxillofacial Surgery, First Affiliated Hospital of Nanchang University, Jiangxi Province, China.

Objective: The aim of this study is to evaluate the feasibility and aesthetic results when comparing two cosmetic approaches that were employed in parotidectomy according to the tumour location with the traditional Blair approach.

Design: Retrospective study.

Setting: Tertiary Referral Centre. Read More

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Histomorphological comparison of pleomorphic adenoma in major and minor salivary glands of oral cavity: A comparative study.

J Oral Maxillofac Pathol 2019 Sep-Dec;23(3):356-362

Department of Oral Medicine and Radiology, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Bengaluru, Karnataka, India.

Background And Objectives: Pleomorphic adenoma, being the most common benign tumors of salivary gland, is morphologically characterized by a biphasic pattern containing the epithelial and mesenchymal components. The modified myoepithelial cells present are thought to play an important role in its histologic diversity by the formation of extracellular matrix. The aim of the present study was to observe, compare and correlate the histomorphological diversity of epithelial and stromal components along with different morphological cell types of modified myoepithelial cells. Read More

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January 2020

Expression of Paxillin in Benign and Malignant Salivary Gland Tumors.

J Dent (Shiraz) 2019 Dec;20(4):249-254

Dept. of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Statement Of The Problem: Paxillin is a major cytoskeletal protein aberrantly deregulated in various human cancers and involved in tumor growth and invasion. However, the clinicopathological and prognostic significance of paxillin in salivary gland tumors (SGTs) is still unclear.

Purpose: This study was conducted to evaluate the relationship between paxillin expression and clinicopathological features of patients with SGTs. Read More

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December 2019

Salivary Gland Tumors: A Clinicopathologic Analysis From Taipei Veterans General Hospital.

Ann Plast Surg 2020 01;84(1S Suppl 1):S26-S33

Institute of Environmental and Occupational Health Sciences, School of Medicine, National Yang-Ming University, Taipei, Taiwan.

Background: The aim of this study was to investigate the epidemiological and clinical characteristics of salivary gland tumors (SGTs) in a Taiwanese population and to provide data for comparison with other studies in various locations and racial populations.

Methods: We retrospectively analyzed the medical records of 559 patients with tumors of the salivary glands who were surgically treated from 2002 to 2017 at a single institution.

Results: There were 430 benign and 129 malignant tumors with a mean age of 53. Read More

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January 2020

A 4-Year Retrospective Analysis of Salivary Gland Cytopathology Using the Milan System for Reporting Salivary Gland Cytology and Ancillary Studies.

Cancers (Basel) 2019 Dec 1;11(12). Epub 2019 Dec 1.

Department of Cytology and Pathology, Toulouse Cancer University Institute, CHU Toulouse, CEDEX, 31059 Toulouse, France.

The cytopathology of salivary glands presents major challenges due to the heterogeneity of benign and malignant neoplasms, which is reflected in the large range of WHO 2017 Classifications. Fine needle aspiration (FNA) of salivary gland tumours is still the favoured initial approach as it results in good sensitivity and specificity. The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) was published in 2018 and comprises seven categories. Read More

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December 2019

Sialolipoma of Parotid Gland a Rare Histological Presentation.

Indian J Otolaryngol Head Neck Surg 2019 Oct 4;71(Suppl 1):805-808. Epub 2019 Jan 4.

Department of Otorhinolaryngology and Head & Neck Surgery, Navodaya Medical College, Raichur, Karnataka India.

Sialolipoma is a rare tumour found within both major and minor salivary glands, it is recently described as a variant of salivary gland lipoma. Sialolipoma was first described by Pusiol et al. (Indian J Pathol Microbiol 52(3):379-382, 2009). Read More

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October 2019

To Study the Role of FNAC in Pre-operative Diagnostic Work Up and Management in Parotid Tumours.

Indian J Otolaryngol Head Neck Surg 2019 Oct 17;71(Suppl 1):497-500. Epub 2018 Apr 17.

Department of ENT, LN Medical College and JK Hospital, Bhopal, M.P India.

Parotid gland is an important major salivary gland connected to the oral cavity. Salivary gland tumours are infrequent around less than 3% of head and neck tumours. Parotid gland is the most common site for the occurrence of salivary tumors. Read More

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October 2019

Thymic stromal lymphopoietin expression from benign lymphoproliferation to malignant B-cell lymphoma in primary Sjögren's syndrome.

Clin Exp Rheumatol 2019 May-Jun;37 Suppl 118(3):55-64. Epub 2019 Aug 27.

Rheumatology Clinic, Udine University Hospital, Department of Medical Area, University of Udine, Italy.

Objectives: To investigate the expression of thymic stromal lymphopoietin (TSLP) in primary Sjögren's syndrome (pSS), stratified according to the lymphoproliferative status, from a fully benign (fbSS) stage to myoepithelial sialadenitis (MESA) and to B-cell non-Hodgkin's lymphoma (NHL).

Methods: After initial serum studies in large numbers of pSS patients and in controls, TSLP was investigated also in pathologic salivary glands (SG) biopsies from 38 stratified pSS patients (13 fbSS; 13 MESA; 12 NHL) and from 13 controls with non-autoimmune sicca syndrome (nSS) by RT-PCR, immunohistochemistry and immunofluorescence.

Results: Significantly higher TSLP serum levels were shown in pSS than controls, increasing from fbSS to MESA and to NHL. Read More

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October 2019

Buccal oncocytoma: Report of a case and literature review.

Ann Med Surg (Lond) 2019 Jul 5;43:82-84. Epub 2019 Jun 5.

Department of Otorhinolaryngology Head and Neck Surgery, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.

Introduction: More common in major salivary glands, oncocytomas are very rare tumors. They commonly occur in the parotid gland and are painless slow growing predominantly benign tumors. The term "oncocytoma" was introduced by Jaffe to designate those tumors of the salivary glands that consist predominantly of oncocytic cells lining the salivary ducts (1) Similalry, Meza- Chavez had proposed the name "oxyphilic granular cell adenoma. Read More

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Solitary fibrous tumour of the parotid gland: a case report and a 15-year literature review.

AME Case Rep 2019 24;3:14. Epub 2019 May 24.

Department of Otolaryngology, Khoo Teck Puat Hospital, Singapore.

Solitary fibrous tumour (SFT) is uncommonly found in the salivary glands and is a rare group of spindle-cell tumours. A review of literature revealed only 40 reported cases of SFT of major salivary glands over a 15-year period from 2004 to 2018. SFTs of the salivary glands are usually benign, although rarely, can be aggressive and may sometimes recur after initial resection. Read More

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Amide Proton Transfer-weighted MRI in the Diagnosis of Major Salivary Gland Tumors.

Sci Rep 2019 06 6;9(1):8349. Epub 2019 Jun 6.

Department of Radiology, Seoul National University Bundang Hospital, 82, Gumi-ro 173beon-gil Bundang-gu, Seongnam, Republic of Korea.

Amide proton transfer-weighted magnetic resonance imaging (APTw-MRI), which is effective in tumor characterization, has expanded its role in the head and neck. We aimed to evaluate the diagnostic ability of APTw-MRI in differentiating malignant from benign major salivary gland tumors compared with diffusion-weighted imaging (DWI) and dynamic contrast-enhanced (DCE)-MRI. Between December 2017 and November 2018, 38 subjects, who were diagnosed with major salivary gland tumors and who underwent preoperative 3 T MRI, including APTw-MRI, DWI, and DCE-MRI, were included in this retrospective study. Read More

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Fine needle aspiration cytology of minor salivary gland tumors: A retrospective 5-year study of 42 cases in a tertiary care hospital.

J Cancer Res Ther 2019 Jul-Sep;15(3):686-689

Department of Pathology, R. G. Kar Medical College and Hospital, Kolkata, West Bengal, India.

Background: Minor salivary gland tumors (MSGTs) are less common than major salivary glands and involve only 15-20% of all salivary gland tumors. Most of the cases originate at intra- and peri-oral region. Minor salivary gland lesion cytology has been studied rarely in India. Read More

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November 2019

Proteomic Investigation of Malignant Major Salivary Gland Tumors.

Head Neck Pathol 2020 Jun 16;14(2):362-373. Epub 2019 May 16.

Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

The purpose of this study was to define the proteome profile of fine needle aspiration (FNA) samples of malignant major salivary gland tumors (MSGT) compared to benign counterparts, and to evaluate potential clinical correlations and future applications. Patients affected by MSGT (n = 20), pleomorphic adenoma (PA) (n = 37) and Warthin's tumor (WT) (n = 14) were enrolled. Demographic, clinical and histopathological data were registered for all patients. Read More

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Magnetic Resonance Imaging and Histopathology in a Case of Pleomorphic Adenoma of a Minor Salivary Gland in the Nasal Cavity.

Am J Case Rep 2019 May 12;20:679-684. Epub 2019 May 12.

Department of Radiology, Toho University Ohashi Medical Center, Tokyo, Japan.

BACKGROUND Pleomorphic adenoma of the salivary gland is a common benign tumor of the parotid gland. However, pleomorphic adenoma arising in the minor salivary glands, including the nasopharynx, is uncommon. This report is of a case of nasal pleomorphic adenoma in which the preoperative imaging findings were consistent with the histological features of pleomorphic adenoma of the minor salivary gland, which differs from that of pleomorphic adenoma of the major salivary gland. Read More

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