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Ann Otol Rhinol Laryngol 2019 Apr 16:3489419842582. Epub 2019 Apr 16.

1 Department of Otolaryngology-Head and Neck Surgery, BS, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Objective: To determine the diagnostic accuracy of fine-needle aspiration (FNA) and imaging modalities for low-grade mucoepidermoid carcinoma (MEC) of the parotid gland.

Methods: Retrospective chart review of patients diagnosed with low-grade MEC of the parotid gland following surgical excision between January 2010 and June 2018. Imaging from patients with MEC were randomly mixed with imaging from patients with benign pathology and reviewed in a blinded fashion. Read More

Clin Med Insights Oncol 2019 2;13:1179554919838254. Epub 2019 Apr 2.

Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of New Mexico Hospital, UNM School of Medicine, Albuquerque, NM, USA.

Background: Myoepithelial cell carcinoma is a rare malignant neoplasm of salivary gland origin that typically presents in the parotid gland and minor salivary glands. It has been described previously in head and neck sites such as buccal mucosa, alveolar ridge, and base of tongue.

Methods: A 55-year-old man presented with 30 years of right-sided tongue pain and 10 years of gradually worsening ulceration. Read More

Niger J Clin Pract 2019 Apr;22(4):585-587

Department of Pulmonary Diseases, Health Sciences University Bursa Yuksek Ihtisas Education and Research Hospital, Bursa, Turkey.

Warthin's tumors which can easily be subjected to misinterpretation are encountered commonly in clinical practice. Warthin's tumors which generally have the localization of parotid gland cauda and have a slow growing characteristic can rarely be seen aside from parotid gland; such as cervical lymph nodes and minor salivary glands. A 56-year-old patient's case that comprised atypical coexistence of Warthin tumor with PET/CT scan positive cervical lymph nodes during the diagnostic examination carried out for a pulmonary mass lesion is presented. Read More

BMC Cancer 2019 Apr 11;19(1):350. Epub 2019 Apr 11.

Department of Oral & Maxillofacial - Head & Neck Oncology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Key Laboratory of Stomatology, Shanghai, 200011, China.

Background: Salivary gland carcinoma ranks the sixth in head and neck cancers while it is relatively rare in its incidence. Epidemiological studies have been based mostly on institutional data, leading to selection bias in incidence evaluation. Most population-based cancer registries have grouped cancers of the minor salivary glands with oral cancer instead of with salivary gland carcinoma as a whole, because of the international disease coding. Read More

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Apr;33(4):362-366

To summarize the clinical features, diagnosis and treatment of mucosa-associated lymphoid tissue(MALT) lymphoma in head and neck. The clinical data of 22 hospitalizedpatients with MALT lymphoma in head and neck during the recent 18 years were analyzed retrospectively. Among the 22 cases, 13 patients showed salivary gland lesions, 4 showed larynx and trachea lesions,3 showed nasopharynx lesions and 2 showed thyroid gland lesions. Read More

J Oral Maxillofac Pathol 2019 Feb;23(Suppl 1):27-31

Department of Oral Pathology, Adhiparasakthi Dental College and Hospital, Melmaruvathur, Tamil Nadu, India.

The presence of numerous minor salivary gland tissues in the posterior part of hard palate increases the possibility of salivary gland neoplasms. Minor salivary gland tumor accounts for about 15% of all the salivary gland neoplasms, of which mucoepidermoid carcinoma (MEC) accounts for about 35.9%. Read More

Ear Nose Throat J 2019 Apr 8:145561319839898. Epub 2019 Apr 8.

1 Department of Radiology, University of Chicago, Pritzker School of Medicine, Chicago, IL, USA.

The goal of this study was to determine whether high-resolution magnetic resonance imaging (MRI) microscopy coil imaging can improve the depiction parotid masses. A total of 14 parotid masses, including 7 salivary neoplasms, 2 abnormal lymph nodes, and 5 benign cystic lesions were imaged with T2-weighted and fat-suppressed postcontrast T1-weighted sequences using a 47-mm diameter microscopy coil in addition to conventional MRI sequences acquired with a conventional head and neck neurovascular coil. Compared to conventional parotid MRI sequences, microscopy coil images provided better definition of the margins of neoplasms, provide more detailed definition of lymph node morphology, and better depict certain cyst contents in the superficial portions of the parotid gland. Read More

J Med Primatol 2019 Apr 2. Epub 2019 Apr 2.

Southwest National Primate Research Center at the Texas Biomedical Research Institute, San Antonio, Texas.

Background: Salivary gland neoplasms are rare in non-human primates.

Methods: Thirty-five years of pathology records were reviewed at the Southwest (SNPRC) and Yerkes (YNPRC) National Primate Research Centers. An in-depth literature search for salivary gland neoplasms in non-human primates was performed. Read More

Diagn Cytopathol 2019 Mar 26. Epub 2019 Mar 26.

Department of Pathology & Laboratory Medicine, Hospital of the University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.

Oncocytic and oncocytoid lesions represent a distinct subset of salivary gland lesions. True oncocytic lesions of the salivary gland are entirely composed of oncocytes. These are characterized by the presence of abundant eosinophilic granules due to the presence of abundant cytoplasmic mitochondria. Read More

J Stomatol Oral Maxillofac Surg 2019 Mar 22. Epub 2019 Mar 22.

Department of Otolaryngology-Head and Neck Surgery, University Hospital of Modena, University of Modena and Reggio Emilia, Modena, Italy.

Introduction: Salivary gland malignancies are rare neoplasms whose management has been evolving over the last two decades. Nevertheless, patient outcomes have not improved accordingly.

Objective: In the present paper, factors and variables that could influence Overall, Disease-Specific and Disease-Free Survival, and Loco-Regional Control were analyzed. Read More

Acta Cytol 2019 Mar 25:1-11. Epub 2019 Mar 25.

Department of Pathology, Emory University, Atlanta, Georgia, USA,

Salivary gland tumor aspiration cytology is a useful preoperative test to guide the most appropriate clinical and surgical management for these patients. Although salivary gland cytology is often useful to distinguish between non-neoplastic lesions, benign neoplasms and malignant neoplasms, there remain many challenges in this area. Specifically, these tumors are uncommon and may have considerable morphologic overlap, especially in the setting of a malignant tumor. Read More

JCO Precis Oncol 2019 15;3. Epub 2019 Feb 15.

University of Pennsylvania, Philadelphia, PA.

Gene 2019 Mar 19;701:41-45. Epub 2019 Mar 19.

Department of Dentistry, Universidade Estadual de Montes Claros, Montes Claros, Minas Gerais, Brazil; Dilson Godinho Hospital, Montes Claros, Minas Gerais, Brazil. Electronic address:

Background: There is significant controversy in the literature regarding the relationship between hypoxia and salivary gland neoplasms (SGNs).

Objective: The current study aims to investigate levels of hypoxia markers in both benign and malignant salivary neoplasms.

Patients And Methods: The current study sample is comprised of a total of 62 samples. Read More

J Stomatol Oral Maxillofac Surg 2019 Mar 9. Epub 2019 Mar 9.

Faculty of Dental Sciences, Ramaiah University of Applied Sciences, India.

Background: Oral cancer is one of the highly prevalent cancers worldwide being. According to data of GLOBOCAN 2018, the estimated incidence, mortality and 5-year survival rates due to lip, oral cavity and salivary gland cancer in world is (2.0%), (0. Read More

Am J Dermatopathol 2019 Feb 28. Epub 2019 Feb 28.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Cutaneous mixed tumors, also known as chondroid syringomas, are benign adnexal neoplasms that share histomorphologic features with pleomorphic adenomas of the salivary gland. Recent work suggests that the similarity between these 2 tumor types extends to the molecular level because both harbor identical chromosomal rearrangements involving the PLAG1 gene. The resulting nuclear PLAG1 overexpression can be detected by immunohistochemistry and has become a useful diagnostic adjunct for both tumor types. Read More

J Craniofac Surg 2019 Feb 5. Epub 2019 Feb 5.

Department of Biomorphology.

Background: Minor salivary gland tumors (MSGTs) are infrequent, representing 10% to 15% of all salivary neoplasms. Despite this low frequency, a significant increase in the incidence of these tumors has been reported in the lasts 30 years. While tumors of the salivary glands can appear at any age, different authors consider the peak of incidence to be associated with old age (60+). Read More

Lung India 2019 Mar-Apr;36(2):118-122

Department of Cancer Surgery, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

Introduction: Primary salivary gland-type tumors of the lung (PSGTTL) are rare intrathoracic malignant neoplasms. Their description in literature is largely limited to a few case series and case reports. A systematic review and pooled analysis of the previously reported cases of PSGTTL is presented here. Read More

J Cancer Res Clin Oncol 2019 Apr 26;145(4):1055-1062. Epub 2019 Feb 26.

Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.

Purpose: Submandibular gland (SMG) carcinoma has an unfavorable clinical course and a low survival rate. Specific tumor and nodal findings might help predict posttreatment recurrence and survival in SMG carcinoma patients. This study evaluated factors predictive of posttreatment recurrence and survival in SMG carcinoma patients. Read More

Histopathology 2019 Feb 23. Epub 2019 Feb 23.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

Aims: Secretory carcinoma (previously known as mammary analog secretory carcinoma) is characterized by ETV6 rearrangements, most often ETV6-NTRK3 fusion. Given its histologic overlap with other salivary gland tumors, secretory carcinoma can be difficult to diagnose without genetic confirmation. A recently developed pan-TRK antibody shows promise for identifying tumors with NTRK fusions. Read More

Am J Surg Pathol 2019 May;43(5):601-609

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY.

Myoepithelial carcinoma (MECA) is an underrecognized challenging entity with a broad morphologic spectrum. Misinterpreting MECA is not uncommon as distinguishing it from its mimics, especially cellular myoepithelial-rich pleomorphic adenoma (PA), can be difficult. We described 21 histologically challenging cases of MECAs (16 MECA ex-PA and 5 MECA de novo). Read More

Einstein (Sao Paulo) 2019 Feb 18;17(1):eRC4610. Epub 2019 Feb 18.

Universidade Estadual da Paraíba, Campina Grande, PB, Brazil.

Spindle cell squamous cell carcinoma of the tongue is a rare variant of squamous cell carcinoma. This paper reports the case of a spindle cell squamous cell carcinoma of the tongue, in a 64-year-old male patient, and presents a review of the etiopathogenesis, clinicopathological and immunohistochemical features and treatment of the malignancy. The patient presented for evaluation of a painful swelling on his tongue. Read More

Oral Dis 2019 May 5;25(4):1084-1090. Epub 2019 Mar 5.

Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.

Objective: Necrotizing sialometaplasia (NS) is an uncommon benign process which affects minor and, more rarely, major salivary glands. While self-limiting, the condition might be clinically and histologically mistaken for malignancy. Furthermore, NS may accompany neoplasms. Read More

Eur J Cancer 2019 Mar 13;110:62-70. Epub 2019 Feb 13.

Department of Medical Oncology, Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, the Netherlands. Electronic address:

Aim: Salivary duct carcinoma (SDC), an aggressive subtype of salivary gland cancer, is androgen receptor (AR)-positive in 67-96% of cases. In patients with locally recurrent and metastatic (R/M) AR-positive SDC, androgen deprivation therapy (ADT) has an overall response rate of 18-64.7%. Read More

J Ultrason 2018 ;18(75):369-373

Department of Otorhinolaryngology, Head and Neck Surgery , Klinikum Augsburg, Augsburg , Germany.

Synchronous unilateral tumors in the parotid glands account for less than 5-10% of all salivary gland neoplasms. Mostly these are cystadenolymphomas, but tumors of different histological types can be found as well. In these cases it is often pleomorphic adenoma in combination with cystadenolymphoma. Read More

Pathol Int 2019 Feb 6;69(2):76-85. Epub 2019 Feb 6.

Department of Oral Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan.

Alpha-L-fucose is a component of glycans on the cell surface. Alpha-L-fucose is correlated with tumorigenesis and malignancy, and alpha-L-fucosidase-1 (FUCA1), the enzyme that removes terminal α-L-fucose residues from glycoproteins, is downregulated in some high malignancy cancers. The expression profile of FUCA1 in head and neck tumors remains unknown, and we analyzed the expression profiles of FUCA1 and an upstream molecule p53 in mucoepidermoid carcinoma (MEC) and oral squamous cell carcinoma (OSCC). Read More

Rev Med Chil 2018 Dec;146(10):1159-1166

Departamento de Anatomía Patológica, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Background: Epithelial tumors of the salivary glands, including benign tumors and aggressive malignancies with different prognoses, are uncommon.

Aim: To describe the frequency and distribution of salivary gland tumors according to age, gender and anatomical location.

Material And Methods: Review of pathological reports of salivary gland tumors of a Pathology laboratory at a clinical hospital from 2006 to 2016. Read More

Head Neck 2019 Apr 5;41(4):924-929. Epub 2019 Feb 5.

Department of Otorhinolaryngology-Head and Neck Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: Salivary gland neoplasms are relatively rare and comprise only 1%-4% of all human neoplasms. Salivary gland neoplasms also show an extremely wide range of morphological diversity. Currently, the genetic alterations and corresponding molecular mechanisms underlying salivary gland neoplasms development remain largely unknown. Read More

Anticancer Res 2019 Feb;39(2):1043-1049

Department of Head and Neck Surgery, Aichi Cancer Center, Nagoya, Japan.

Aim: To investigate whether F-fluorodeoxyglucose uptake is associated with overall survival in patients with major salivary gland cancer using univariate and multivariate analyses after adjusting for pathological stage (eighth edition of the International Union Against Cancer).

Patients And Methods: A total of 32 patients with major salivary gland cancer treated with curative surgery were enrolled. Parameters for F-fluorodeoxyglucose uptake were assessed by positron-emission tomography combined with computed tomography. Read More

Anticancer Res 2019 Feb;39(2):641-647

Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Rappaport Family Institute for Research in the Medical Sciences, Technion - Israel Institute of Technology, Haifa, Israel

Background: The diversity of malignant salivary gland tumors challenges the study of survival rates. The current study evaluated patient survival rates using Kaplan-Meier analysis and examined the relative effects of histology, grade and stage on survival.

Materials And Methods: Using the Kaplan-Meier model, cancer-specific (CSS) and disease-free (DFS) survival probabilities were calculated as a function of time. Read More

Haematologica 2019 Mar 31;104(3):444-455. Epub 2019 Jan 31.

Division of Rheumatology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.

IgG4-related disease is a fibro-inflammatory condition that can affect nearly any organ system. Common presentations include major salivary and lacrimal gland enlargement, orbital disease, autoimmune pancreatitis, retroperitoneal fibrosis and tubulointerstitial nephritis. This review focuses on the hematologic manifestations of IgG4-related disease, including lymphadenopathy, eosinophilia, and polyclonal hypergammaglobulinemia. Read More

Cancer Imaging 2019 Jan 31;19(1). Epub 2019 Jan 31.

Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth Peoples Hospital, College of Stomatology Shanghai Jiao Tong University School of Medicine, No. 639 Zhizaoju Road, Shanghai, 200011, China.

Background: To evaluate the computed tomographic features and create a prediction model for clinical diagnosis of adenoid cystic carcinoma (ACC) in the palate with intact mucosa.

Methods: From March 2016 to May 2018, 102 patients with palatal tumors and intact mucosa, including 28 patients with a pathological diagnosis of ACC after surgery, were enrolled in this study. The patients' clinical symptoms, computed tomographic features and pathological diagnoses were recorded and analyzed. Read More

Arch Craniofac Surg 2019 Feb 1;20(1):55-57. Epub 2019 Feb 1.

Department of Plastic and Reconstructive Surgery, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea.

Pleomorphic adenoma is the most common benign tumor of the salivary gland. Pleomorphic adenoma occurs most commonly in the parotid gland but it may involve other salivary gland such as submandible or lingual. We report an ectopic pleomorphic adenoma in the subcutaneous layer of the face. Read More

Medicine (Baltimore) 2019 Feb;98(5):e14270

Department of Nuclear Medicine, Lanzhou University Second Hospital, Lanzhou University.

Rationale: Mucosa-associated lymphoid tissue (MALT) lymphoma is an extranodal low-grade B cell lymphoma that generally exhibits an indolent clinical course. Currently, the application of F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) in MALT lymphoma is still controversial. Herein, we reported a case of using F-FDG PET/CT for staging and response assessment of primary parotid MALT lymphoma with multiple sites involvement. Read More

Ann Otol Rhinol Laryngol 2019 May 30;128(5):413-419. Epub 2019 Jan 30.

2 Supportive Care Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Introduction: In head and neck cancer (HNC) patients, fatigue is present throughout the course of treatment and during follow-up. There are limited data about the prevalence and factors associated with fatigue in HNC survivors. The objectives of this study were to assess the prevalence of fatigue and its interference with daily life activities and examine the association between fatigue and gender, age, primary tumour site, Human Papillomavirus (HPV) status, previous oncologic therapy, and time since end of treatment. Read More

Iran J Pathol 2018 17;13(2):220-228. Epub 2018 Jul 17.

Dept. of Pathology, Integral Institute of Medical Sciences and Research, Lucknow, India.

Background & Objective: Fine needle aspiration cytology (FNAC) of salivary gland lesions is an accepted and useful diagnostic tool to differentiate between benign and malignant lesions. Majority of the neoplasms are benign, and specific diagnosis on cytology can be made in most of the cases. However, the utility is limited by the overlapping and heterogeneous morphological features of benign and malignant neoplasms. Read More

NPJ Breast Cancer 2019 18;5. Epub 2019 Jan 18.

1Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY USA.

Breast adenomyoepitheliomas (AMEs) are rare epithelial-myoepithelial neoplasms that may occasionally produce myxochondroid matrix, akin to pleomorphic adenomas (PAs). Regardless of their anatomic location, PAs often harbor rearrangements involving or . We have recently shown that the repertoire of somatic genetic alterations of AMEs varies according to their estrogen receptor (ER) status; whilst the majority of ER-positive AMEs display mutually exclusive or hotspot mutations, up to 60% of ER-negative AMEs harbor concurrent Q61 hotspot mutations and mutations affecting either or . Read More

Nat Commun 2019 01 21;10(1):368. Epub 2019 Jan 21.

Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstr. 8-10, 91054, Erlangen, Germany.

The molecular pathogenesis of salivary gland acinic cell carcinoma (AciCC) is poorly understood. The secretory Ca-binding phosphoprotein (SCPP) gene cluster at 4q13 encodes structurally related phosphoproteins of which some are specifically expressed at high levels in the salivary glands and constitute major components of saliva. Here we report on recurrent rearrangements [t(4;9)(q13;q31)] in AciCC that translocate active enhancer regions from the SCPP gene cluster to the region upstream of Nuclear Receptor Subfamily 4 Group A Member 3 (NR4A3) at 9q31. Read More

Otolaryngol Pol 2018 Sep;72(6):23-30

Collegium Medicum Uniwersytetu Mikołaja Kopernika w Toruniu Klinika Otolaryngologii i Laryngologii Onkologicznej z Pododdziałem Audiologii i Foniatrii.

Introduction Warthin's tumor is a non-malignant tumor that occurs in major salivary glands. Diagnostics include an interview and physical examination as well as additional tests - ultrasonography, magnetic resonance tomography, fine-needle aspiration biopsy. Surgical tumor resection remains the method of treatment, the scope of which includes techniques from extracapsular tumor resection to a full range of parotidectomy. Read More

Pan Afr Med J 2018 30;30:300. Epub 2018 Aug 30.

Service de Dermatologie-Vénérologie, Hôpital d'Instruction Mohammed V, Rabat, Maroc.

Basal cell carcinoma (BCC) is the most frequent skin cancer. It never affects the mucosa. It is characterized by a local malignancy with an extremely rare risk of developing distant metastasis and the lowest mortality. Read More

Clin Otolaryngol 2019 Jan 12. Epub 2019 Jan 12.

Department of Otolaryngology Head and Neck Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan (R.O.C.).

Objectives: To validate and compare ultrasound (US) versus computerized tomography (CT) criteria in the localisation of superficial/deep lobe tumours of the parotid gland.

Design And Setting: This was a retrospective study of diagnostic tests performed from January 2008 to June 2017.

Participants: We included adult patients who were referred for a neck ultrasonography examination due to parotid tumours, and who subsequently underwent parotid surgery. Read More

Radiat Oncol J 2018 Dec 31;36(4):317-324. Epub 2018 Dec 31.

Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Purpose: This study aimed to evaluate the long-term survival outcomes and prognostic factors that affect the clinical outcomes of patients who underwent surgery and postoperative radiotherapy for major salivary gland mucoepidermoid carcinoma (MEC).

Materials And Methods: We retrospectively reviewed the clinical data of 44 patients who underwent surgery followed by radiotherapy for primary MEC of the major salivary glands between 1991 and 2014. The median follow-up period was 9. Read More

Zhonghua Kou Qiang Yi Xue Za Zhi 2019 Jan;54(1):10-16

Department of Pathology, Hospital of Stomatology, Jilin University, Changchun 130021, China.

To investigate the incidence and proportion of salivary gland tumors in order to provide new thinking for clinical diagnosis and treatment. Collected 3 724 cases salivary gland tumors diagnosed by Pathology Department of Hospital of Stomatology, Jilin University from January 1961 to December 2016. The pathological diagnosis referred to the fourth edition of head and neck-salivary gland tumor histopathological classification standard of WHO. Read More

Am J Otolaryngol 2019 Mar - Apr;40(2):289-291. Epub 2018 Dec 21.

Coordinator of the International Head and Neck Scientific Group, Padua, Italy.

A wide variety of tumors, both benign and malignant, occur in the parapharyngeal space. Depending on histology and extent, treatment may include surgery and/or radiotherapy (RT). Herein we discuss the role of RT in the management of some of the more commonly encountered neoplasms, including salivary gland tumors, paragangliomas, schwannomas, and soft-tissue sarcomas. Read More

Bull Exp Biol Med 2019 Jan 8;166(3):383-385. Epub 2019 Jan 8.

I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation, Moscow, Russia.

The benign and malignant neoplasms in parotid gland have similar clinical presentations despite different tumor growth rates. The study compared the clinical and morphological data as well as the results of ELISA for MMP-2, MMP-8, MMP-9, TIMP-1, and TIMP-2 in salivary fluid yielded during primary examination of the patients with pleomorphic adenoma and adenocarcinoma of parotid gland. The examined biomarkers detected in salivary fluid in patients with various cancer types differed significantly (p≤0. Read More

Nucl Med Commun 2019 Mar;40(3):264-269

Norwich Radiology Academy, The Cotman Centre, Norwich.

Objective And Aim: The increased use of PET/CT in cancer staging has resulted in more incidental findings in unexpected locations, making this a challenge for the radiologist interpreting the study. Our aim was to determine the frequency of parotid incidentalomas and to assess the ability of PET/CT to characterize them.

Patients And Methods: At the Norfolk and Norwich University Trust, in between October 2010 to October 2015, 4044 patients had a PET/CT examination. Read More

Arch Craniofac Surg 2018 Dec 27;19(4):279-282. Epub 2018 Dec 27.

Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea.

Primary malignant lymphoma rarely presents as a mass in the salivary gland. It accounts for about 1% of salivary gland tumors. The lymphomas of the parotid gland are mainly non-Hodgkin's lymphoma of B-cell follicular type. Read More

Head Neck Pathol 2019 Jan 4. Epub 2019 Jan 4.

Department of Pathology and Laboratory Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave, L25, Cleveland, OH, 44195, USA.

Intraductal carcinomas (IDCs) of salivary gland are rare neoplasms. Here, we report a case of IDCs harboring TRIM27-RET fusion with mixed low grade and apocrine types. A 79-year-old male presented with slowly-growing left parotid mass for 2. Read More

Ann Otol Rhinol Laryngol 2019 Apr 2;128(4):357-359. Epub 2019 Jan 2.

1 Department of Surgery, Division of Otolaryngology-Head & Neck Surgery, University of California, San Diego, CA, USA.

Objectives:: To report a case of total facial paralysis as the result of a core needle biopsy.

Methods:: Case report and literature review.

Results:: A 70-year-old man was diagnosed with a deep lobe parotid tumor on computed tomography. Read More