38,443 results match your criteria Sacral Plexus

Sacral dural arteriovenous fistula supplied by bilateral lateral sacral arteries: case report and literature review.

Br J Neurosurg 2021 May 13:1-4. Epub 2021 May 13.

Department of Neurosurgery, West China Hospital of Sichuan University, Chengdu, PR China.

Sacral dural arteriovenous fistulas (DAVFs) with bilateral arterial supplies are extremely rare. To date, only two cases with arterial supply from bilateral lateral sacral arteries (LSAs) were reported. We report a rare case of sacral DAVF with arterial supply from bilateral LSAs. Read More

View Article and Full-Text PDF

Distal Stimulation Site at the Medial Tibia for Saphenous Nerve Somatosensory Evoked Potentials (DSn-SSEPs) in Lateral Lumbar Spine Procedures.

Neurodiagn J 2021 May 5:1-14. Epub 2021 May 5.

Axis Neuromonitoring, Richardson, Texas.

Lateral lumbar interbody fusion procedures are performed with multimodality neuromonitoring of the femoral nerve to prevent lumbosacral plexus and peripheral nerve injury from positioning, dilation, retraction, and hardware implantation. The integrity of the femoral nerve can be continuously assessed during these procedures by Somatosensory Evoked Potentials of the Saphenous nerve (Sn-SSEPs). Sn-SSEPs are technically challenging to acquire and necessitate advanced troubleshooting skills with a more rigid anesthetic regimen and physiological parameters. Read More

View Article and Full-Text PDF

Treatment of Degenerative Lumbar Scoliosis with Oblique Lumbar Interbody Fusion in Conjunction with Unilateral Pedicle Screw Fixation via the Wiltse Approach.

Orthop Surg 2021 May 4. Epub 2021 May 4.

Department of Orthopedics, General Hospital of Ningxia Medical University, Yinchuan, China.

Objective: To evaluate the clinical outcomes of oblique lumbar interbody fusion (OLIF) in conjunction with unilateral pedicle screw fixation (UPSF) via the Wiltse approach in treating degenerative lumbar scoliosis (DLS).

Methods: The article is a retrospective analysis. Twelve patients with DLS who underwent combined OLIF and UPSF between July 2017 and December 2018 were included. Read More

View Article and Full-Text PDF

Near-infrared intraoperative imaging of pelvic autonomic nerves: a pilot study.

Surg Endosc 2021 Apr 28. Epub 2021 Apr 28.

Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Zhuhai, Guangdong Province, 519000, China.

Background: The pelvic autonomic nerves control and regulate anorectal and urogenital function. The dysfunction of pelvic autonomic nerves lead to disorders of anorectum, bladder and male sex organs. Thus the intraoperative identification of pelvic autonomic nerves could be crucial in complications prevention and diseases treatment. Read More

View Article and Full-Text PDF

Lumbosacral plexopathy due to pelvic hematoma after extracorporeal membrane oxygenation: A case report.

Medicine (Baltimore) 2021 Apr;100(17):e25698

Department of Neurology, Washington University School of Medicine, Saint Louis, MO.

Rationale: Peripheral nerve injury related to vascular complications associated with extracorporeal membrane oxygenation (ECMO) is perhaps underappreciated. Compared to the well-described central nervous system complications of ECMO, brachial plexopathy and lumbosacral plexopathy have rarely been reported. We report this case to heighten awareness of lumbosacral plexus injury due to pelvic hematoma formation after ECMO. Read More

View Article and Full-Text PDF

Topography of the pelvic autonomic nerves - an anatomical study to facilitate nerve-preserving total mesorectal excision.

Acta Chir Belg 2021 Apr 27:1-23. Epub 2021 Apr 27.

Division of Macroscopic and Clinical Anatomy, Medical University of Graz, Graz, Austria.

Introduction: Urogenital dysfunction caused by iatrogenic injury to the autonomic nerves persists as a common complication of rectal cancer surgery. This study aims to investigate the relationship between autonomic nerves and the 'holy plane' with the intention of identifying hazardous sites at which urogenital dysfunction may occur.

Patients And Methods: Dissection of the 'holy plane' and preparation of the autonomic nerves was performed on -embalmed bodies. Read More

View Article and Full-Text PDF

GluN2B-BDNF pathway in the cerebrospinal fluid-contacting nucleus mediates nerve injury-induced neuropathic pain in rats.

Sheng Li Xue Bao 2021 Apr;73(2):223-232

Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou 221004, China.

The present study was aimed to investigate the role of GluN2B-BDNF pathway in the cerebrospinal fluid-contacting nucleus (CSF-CN) in neuropathic pain. Intra-lateral ventricle injection of cholera toxin subunit B conjugated with horseradish peroxidase (CBHRP) was used to label the CSF-CN. Double-labeled immunofluorescent staining and Western blot were used to observe the expression of GluN2B and BDNF in the CSF-CN. Read More

View Article and Full-Text PDF

AAV2/9-mediated silencing of PMP22 prevents the development of pathological features in a rat model of Charcot-Marie-Tooth disease 1 A.

Nat Commun 2021 04 21;12(1):2356. Epub 2021 Apr 21.

INM, Univ. Montpellier, INSERM, Montpellier, France.

Charcot-Marie-Tooth disease 1 A (CMT1A) results from a duplication of the PMP22 gene in Schwann cells and a deficit of myelination in peripheral nerves. Patients with CMT1A have reduced nerve conduction velocity, muscle wasting, hand and foot deformations and foot drop walking. Here, we evaluate the safety and efficacy of recombinant adeno-associated viral vector serotype 9 (AAV2/9) expressing GFP and shRNAs targeting Pmp22 mRNA in animal models of Charcot-Marie-Tooth disease 1 A. Read More

View Article and Full-Text PDF

Identifying lumbosacral plexus nerve root abnormalities in patients with sciatica using 3T readout-segmented echo-planar diffusion weighted MR neurography.

Insights Imaging 2021 Apr 20;12(1):54. Epub 2021 Apr 20.

Department of Radiology, Mater Misericordiae University Hospital, Eccles Street, Dublin7, Dublin, Ireland.

Objectives: To investigate the accuracy of Diffusion Weighted Imaging (DWI) using the Readout Segmentation of Long Variable Echo-trains (RESOLVE) sequence in detecting lumbosacral nerve abnormalities.

Methods: Following institutional ethics committee approval, patients with sciatica-type lower limb radicular symptoms (n = 110) were recruited and prospectively scanned using 3T MRI. Additional participants (n = 17) who underwent neurophysiological testing (EMG/NCV), were also prospectively studied. Read More

View Article and Full-Text PDF

Diaphragmatic paralysis resulting in respiratory failure as a feature of hepatitis E virus-associated neuralgic amyotrophy.

BMJ Case Rep 2021 Apr 13;14(4). Epub 2021 Apr 13.

Neurology, University Hospitals Plymouth NHS Trust, Plymouth, UK.

Hepatitis E virus (HEV)-associated neuralgic amyotrophy (NA) is often bilateral and severe, involving structures outside the brachial plexus, such as the phrenic nerves or the lumbosacral plexus. We report a case of an HEV-positive man who had presented with brachial neuritis, with significant phrenic nerve involvement, resulting in diaphragmatic paralysis requiring non-invasive ventilation. Prognosis of HEV-associated NA is often unfavourable and recovery is usually incomplete. Read More

View Article and Full-Text PDF


Wiad Lek 2021 ;74(3 cz 2):619-624


Objective: The aim: Improving the effectiveness of patients' treatment with combat injuries of the peripheral nervous system, which consists in the application and development of new methods of reconstructive interventions, optimizing a set of therapeutic and diagnostic measures for the most effective management of this category of patients with peripheral nerve injury.

Patients And Methods: Materials and methods: The research is based on the results of surgical treatment of 138 patients with combat injuries of peripheral nerves for the period from 2014 to 2020. The mean age was 33. Read More

View Article and Full-Text PDF

Femoral nerve block versus fascia iliaca block for pain control in knee and hip arthroplasties: A meta-analysis.

Medicine (Baltimore) 2021 Apr;100(14):e25450

Department of Anesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology.

Background: This meta-analysis aimed to compare the efficiency of fascia iliaca compartment block (FICB) and femoral nerve block (FNB) for pain management in knee and hip surgeries.

Methods: We searched four electronic databases (Pubmed, Embase, Cochrane library database, Web of Science) from inception to January 2019. Only randomized controlled trials (RCTs) were included. Read More

View Article and Full-Text PDF


Wiad Lek 2021 ;74(2):207-212


Objective: The aim: Is to find out the features of innervation of the skin of the anterior femoral region and the fascia lata during the fetal period of human development.

Patients And Methods: Materials and methods: The study was carried out on 64 preparations of the lower extremities of human fetuses of 4-10 months using macromicroscopic preparation and morphometry. Macropreparations of the skin nerves of the lower extremities of different age fetuses with anatomical variants were subject to photo documentation. Read More

View Article and Full-Text PDF

Effect of Extract and Synthesized Derivatives of Isolated Compound from f. Pilosa Ohwi on Neuropathic Pain in Mice.

Molecules 2021 Mar 15;26(6). Epub 2021 Mar 15.

Department of Food Science and Nutrition, Hallym University, 1 Hallymdeahak-gil, Chuncheon 24252, Korea.

Neuropathic pain is described as the "most terrible of all tortures that a nerve wound may inflict." The aim of the present study was to demonstrate the antinociceptive effect of f. pilosa Ohwi water extract (SCW) and synthesized derivatives of the isolated compound. Read More

View Article and Full-Text PDF

Exendin-4 Promotes Schwann Cell Survival/Migration and Myelination In Vitro.

Int J Mol Sci 2021 Mar 15;22(6). Epub 2021 Mar 15.

Diabetic Neuropathy Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.

Besides its insulinotropic actions on pancreatic β cells, neuroprotective activities of glucagon-like peptide-1 (GLP-1) have attracted attention. The efficacy of a GLP-1 receptor (GLP-1R) agonist exendin-4 (Ex-4) for functional repair after sciatic nerve injury and amelioration of diabetic peripheral neuropathy (DPN) has been reported; however, the underlying mechanisms remain unclear. In this study, the bioactivities of Ex-4 on immortalized adult rat Schwann cells IFRS1 and adult rat dorsal root ganglion (DRG) neuron-IFRS1 co-culture system were investigated. Read More

View Article and Full-Text PDF

Hemodynamically unstable pelvic fracture: A damage control surgical algorithm that fits your reality.

Colomb Med (Cali) 2020 Dec 30;51(4):e4214510. Epub 2020 Dec 30.

University of Colorado, Denver Health Medical Center, Department of Surgery, Denver, CO USA.

Pelvic fractures occur in up to 25% of all severely injured trauma patients and its mortality is markedly high despite advances in resuscitation and modernization of surgical techniques due to its inherent blood loss and associated extra-pelvic injuries. Pelvic ring volume increases significantly from fractures and/or ligament disruptions which precludes its inherent ability to self-tamponade resulting in accumulation of hemorrhage in the retroperitoneal space which inevitably leads to hemodynamic instability and the lethal diamond. Pelvic hemorrhage is mainly venous (80%) from the pre-sacral/pre-peritoneal plexus and the remaining 20% is of arterial origin (branches of the internal iliac artery). Read More

View Article and Full-Text PDF
December 2020

Effects of varying degrees of ligation in a neuropathic pain model induced by chronic constriction injury.

Life Sci 2021 Jul 29;276:119441. Epub 2021 Mar 29.

The First School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China; Department of Neurology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China. Electronic address:

Aim: Ligature tightness of chronic constriction injury (CCI) model remains inconsistent and controversial, presenting barriers for researchers.

Methods: We summarized the different ligation criteria in literature and attempted to clarify their effects. To assess constriction under different criteria, we calculated the radial strain (ε) of ligated nerves from digital photographs. Read More

View Article and Full-Text PDF

Incidence and clinical outcome of lateral femoral cutaneous nerve injury after periacetabular osteotomy.

Bone Joint J 2021 Apr;103-B(4):659-664

Department of Orthopaedic Surgery, Fukuoka University Faculty of Medicine Graduate School of Medicine, Fukuoka, Japan.

Aims: Injury to the lateral femoral cutaneous nerve (LFCN) is one of the known complications after periacetabular osteotomy (PAO) performed using the anterior approach, reported to occur in between 1.5% and 65% of cases. In this study, we performed a prospective study on the incidence of LFCN injury as well as its clinical outcomes based on the Harris Hip Score (HHS), Short-Form 36 Health Survey (SF-36), and Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire (JHEQ). Read More

View Article and Full-Text PDF

[Effect of moxibustion on expression of GAP-43 in sciatic nerve trunk and ventral horn of spinal cord of rats with primary sciatica and its nerve repair function].

Zhongguo Zhen Jiu 2021 Feb;41(2):183-8

Department of Geriatrics, Second Affiliated Hospital of Anhui University of CM, Hefei 230000, China.

Objective: To observe the effect of moxibustion at "Huantiao" (GB 30) on the expression of growth-associated protein-43 (GAP-43) in the sciatic nerve trunk and ventral horn of spinal cord (L-L) in rats with primary sciatica, and to explore the mechanism of moxibustion in improving primary sciatica.

Methods: A total of 48 healthy male SD rats were randomly divided into a normal group, a sham operation group, a model group and a moxibustion group, 12 rats in each group. The rat model of primary sciatic pain was established by chronic constriction injury (CCI) of the sciatic nerve in the model group and the moxibustion group. Read More

View Article and Full-Text PDF
February 2021

Microvesicles from Schwann-Like Cells as a New Biomaterial Promote Axonal Growth.

J Biomed Nanotechnol 2021 Feb;17(2):291-302

Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, Jiangsu, China.

Schwann cells promote axonal regeneration following peripheral nerve injury. However, in terms of clinical treatment, the therapeutic effects of Schwann cells are limited by their source. The transmission of microvesicles from neuroglia cells to axons is a novel communication mechanism in axon regeneration. Read More

View Article and Full-Text PDF
February 2021

Comments on "Continuous Pericapsular Nerve Group Block for Hip Surgery: A Case Series".

A A Pract 2021 03 30;15(4):e01435. Epub 2021 Mar 30.

Department of Anaesthesiology, Ganga Medical Centre Pvt Ltd, Coimbatore, India,

View Article and Full-Text PDF

In Response.

Swati Singh

A A Pract 2021 03 30;15(4):e01434. Epub 2021 Mar 30.

Department of Anaesthesiology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India,

View Article and Full-Text PDF

Postoperative lumbar paraspinal compartment syndrome.

BMJ Case Rep 2021 Mar 29;14(3). Epub 2021 Mar 29.

Department of Neurology, University of Chicago, Chicago, Illinois, USA

Lower lumbar paraspinal muscles constitute a compartment as they are surrounded by distinct fascial and bony boundaries. Lumbar paraspinal compartment syndrome is a rare entity, often caused by intense exercise, but also can be a postoperative complication. We present a 60-year-old man with low back pain, numbness in the left lower back and radicular pain in the left lower extremity, which started after a surgery that involved prolonged positioning on the left side 7 years before, and persisted to the day of evaluation. Read More

View Article and Full-Text PDF

Deep infiltrating endometriosis with sacral plexus involvement: Improving knowledge through human cadaver dissection.

J Gynecol Obstet Hum Reprod 2021 Mar 26;50(8):102129. Epub 2021 Mar 26.

Anatomy Laboratory, Jules Verne University of Picardie, Amiens, F-80054, France; Department of Pediatric Orthopedic Surgery, Amiens University Medical Center and Jules Verne University of Picardie, Amiens, F-80054, France. Electronic address:

Introduction: The aim of this study was to assess a human cadaver model of sacral plexus dissection for learning about deep innervation in the female pelvis, and the latter's relationship with deep infiltrating endometriosis.

Methods: This was a prospective, observational study. Eight residents in obstetrics and gynecology were tested before and after a lecture on innervation of the female pelvis and a cadaver dissection class. Read More

View Article and Full-Text PDF

Correction to: Surgical Management of Symptomatic Lumbar, Sacral, and Lumbosacral Plexus Tumors: a Peripheral Nerve Unit Experience.

Acta Neurochir (Wien) 2021 Mar 29. Epub 2021 Mar 29.

Department of Surgery, Gaffrée e Guinle University Hospital, School of Medicine, Federal University of Rio de Janeiro State (UNIRIO), Rio de Janeiro, RJ, Brazil.

View Article and Full-Text PDF

Surgical Neuropelviology: Combined Sacral Plexus Neurolysis and Laparoscopic Laterally Extended Endopelvic Resection in Deep Lateral Pelvic Endometriosis.

J Minim Invasive Gynecol 2021 Mar 26. Epub 2021 Mar 26.

Department of Gynecologic Oncology (Drs. Di Donna, Cucinella, Sozzi, and Chiantera); Department of Surgical, Oncological and Oral Sciences (Di.Chir.On.S.)(Dr. Di Donna), University of Palermo, Palermo; Division of Gynecological Oncology, Department for the Protection of Women's and Children's Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS L.go A. Gemelli, Rome (Drs. Ianieri and Scambia), Italy.

Objective: Surgical demonstration of combined sacral plexus neurolysis and laparoscopic laterally extended endopelvic resection for deep lateral infiltrating endometriosis.

Design: Video showing principles of neurolysis and laparoscopic laterally extended endopelvic resection applied to endometriotic surgery.

Setting: University tertiary referral center. Read More

View Article and Full-Text PDF

Reliability of distally based sural flap in elderly patients: comparison between elderly and young patients in a single center.

BMC Surg 2021 Mar 28;21(1):167. Epub 2021 Mar 28.

Department of Orthopedics, The Second Xiangya Hospital, Central South University, No. 139 Renmin Road, Changsha, 410011, Hunan, China.

Background: Reconstructions the soft-tissue defects of the distal lower extremities in the elderly patients (≥ 60 years old) are full of challenges because of many comorbidities. The purpose of this study was to report the clinical application of the distally based sural flap in the elderly patients, and to verify the reliability of this flap in the elderly patients.

Methods: Between March of 2005 and December of 2019, 53 patients aged over 60-year-old and 55 patients aged 18 to 30-year-old who underwent the procedure have been included in this study. Read More

View Article and Full-Text PDF

Excision of deep endometriosis nodules of the parametrium and sacral roots in 10 steps.

Fertil Steril 2021 Mar 23. Epub 2021 Mar 23.

Department of Obstetrics and Gynecology, Bahrain Defense Force, Royal Medical Services, Riffa, Bahrain.

Objective: To present 10 consecutive, standardized, and reproducible surgical steps allowing complete excision of deep endometriosis nodules infiltrating the parametrium and sacral roots.

Design: Surgical video presenting the 10 surgical steps. Local institutional review board approval was not required for this video article, because the video describes a technique and the patient cannot be identified whatsoever. Read More

View Article and Full-Text PDF

An uncommon cause of nerve stimulator's malfunction during a dual guidance lumbar plexus block: A technical brief report and an algorithm for prevention of complications.

Anaesth Crit Care Pain Med 2021 Apr 18;40(2):100832. Epub 2021 Mar 18.

Department of Anaesthesiology and Critical Care Medicine, Lapeyronie University Hospital, 34295 Montpellier Cedex 5, France. Electronic address:

Posterior Lumbar plexus block (PLPB) combined with an ipsilateral sacral plexus block is a valuable anaesthetic technique in patients undergoing hip fracture surgery. PLPB is performed through the acoustic window of the lumbar ultrasound trident and the position of the needle tip, before injection of LA, was confirmed by observing quadriceps femoris muscle contraction to peripheral nerve stimulation (i.e. Read More

View Article and Full-Text PDF

MBP-activated autoimmunity plays a role in arsenic-induced peripheral neuropathy and the potential protective effect of mecobalamin.

Environ Toxicol 2021 Jun 19;36(6):1243-1253. Epub 2021 Mar 19.

Department of Occupational and Environmental Health, Xiangya School of Public Health, Central South University, Changsha, China.

Intake excessive arsenic (As) is related to the occurrence of peripheral neuropathy. However, both the underlying mechanism and the preventive approach remain largely unknown. In the present study, As treatment significantly decreased the mechanical withdrawal threshold and increased the titer of anti-myelin basic protein antibody in rats, accompanied with damaged BNB. Read More

View Article and Full-Text PDF