15,529 results match your criteria Rubella


Controlling Measles through Politics and Policy.

Authors:
Ross D Silverman

Hastings Cent Rep 2019 Apr 22. Epub 2019 Apr 22.

Vaccination is one of history's most successful public health interventions. Since 2000, vaccination campaigns against measles, which is highly contagious but preventable through the measles-mumps-rubella (MMR) vaccine, have reduced both the global incidence of the disease and measles deaths by 80 percent. However, progress toward measles elimination has slid backward in several previously well-protected global regions. Read More

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http://dx.doi.org/10.1002/hast.996DOI Listing

[Methodology of the 2nd seroprevalence study in Spain].

Rev Esp Salud Publica 2019 Apr 22;93. Epub 2019 Apr 22.

Subdirección General de Promoción de la Salud y Vigilancia en Salud Pública. Dirección General de Salud Pública, Calidad e Innovación. Ministerio de Sanidad, Consumo y Bienestar Social. Madrid. España.

Seroprevalence studies are designed in population samples to assess the level and distribution of immunity induced by natural infection of certain infectious agents or by immunization against them. The purpose of the 2nd Seroprevalence Study in Spain is to assess the prevalence and distribution of immune status against vaccine-preventable diseases and generated by natural infection by other microorganisms. Pathologies specifically included in the study are: poliomyelitis, diphtheria, tetanus, pertussis, measles, rubella, mumps, varicella, invasive meningococcal disease by serogroup C, hepatitis A, hepatitis B, hepatitis E, hepatitis C and HIV. Read More

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Vaccination of Solid Organ Transplant Candidates and Recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.

Clin Transplant 2019 Apr 19:e13563. Epub 2019 Apr 19.

Transplant Infectious Diseases, University Health Network, Toronto, ON.

These updated guidelines of the AST IDCOP review vaccination of solid organ transplant candidates and recipients. General principles of vaccination as well as the use of specific vaccines in this population are discussed. Vaccination should be reviewed in the pre-transplant setting and appropriate vaccines updated. Read More

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http://dx.doi.org/10.1111/ctr.13563DOI Listing

Vaccine hesitancy: An overview on parents' opinions about vaccination and possible reasons of vaccine refusal.

J Public Health Res 2019 Mar 11;8(1):1436. Epub 2019 Mar 11.

Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.

Vaccine hesitancy has increased worldwide with a subsequent decreasing of vaccination rates and outbreaks of vaccine-preventable diseases (i.e. measles, poliomyelitis and pertussis) in several developed countries, including Italy. Read More

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http://dx.doi.org/10.4081/jphr.2019.1436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444379PMC
March 2019
1 Read

Maternal Viral Infection and Risk of Fetal Congenital Heart Diseases: A Meta-Analysis of Observational Studies.

J Am Heart Assoc 2019 May;8(9):e011264

1 Department of Epidemiology and Health Statistics Xiangya School of Public Health Central South University Hunan China.

Background At present, the association between maternal viral infection and risk of congenital heart diseases ( CHD ) in offspring is uncertain; additionally, a complete overview is missing. A meta-analysis of observational studies was performed to address the question of whether women who had a history of viral infection in early pregnancy were at an increased risk of CHD in offspring, compared with mothers without viral infection. Methods and Results Unrestricted searches were conducted, with an end date parameter of July 15, 2018, of PubMed, Embase, Google Scholar, Cochrane Libraries, and Chinese databases, to identify studies that met prestated inclusion criteria. Read More

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https://www.ahajournals.org/doi/10.1161/JAHA.118.011264
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http://dx.doi.org/10.1161/JAHA.118.011264DOI Listing
May 2019
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Comparison of the LIAISON®XL and ARCHITECT IgG, IgM, and IgG avidity assays for the diagnosis of Toxoplasma, cytomegalovirus, and rubella virus infections.

New Microbiol 2019 Apr 17;41(2). Epub 2019 Apr 17.

SC Microbiologia e Virologia Fondazione IRCCS Policlinico San Matteo Pavia, Italy.

This study compared the performance of the LIAISON®XL system of immunoglobulin (Ig) G and IgM immunoassays for the diagnosis of Toxoplasma gondii, cytomegalovirus (CMV), and rubella virus infections with that of the ARCHITECT system. Patient serum samples, previously screened and clinically diagnosed with T. gondii, CMV or rubella, were used to compare LIAISON®XL and ARCHITECT IgG and IgM immunoassays. Read More

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April 2019
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Perception of rubella risk in pregnancy: an epidemiological survey on a sample of pregnant women.

Ann Ig 2019 Mar-Apr;31(2 Supple 1):65-71

Department of Biomedical and Dental Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.

Background: Rubella is a common exanthematous viral disease all over the world. The disease can be prevented by administering a safe and effective vaccine, and in Italy it is subject to reporting obligations. A national plan for the elimination of measles and congenital rubella (in Italian "PNEMoRC") was approved in 2003 and updated in 2010. Read More

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http://dx.doi.org/10.7416/ai.2019.227DOI Listing
April 2019
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Today's vaccination policies in Italy: The National Plan for Vaccine Prevention 2017-2019 and the Law 119/2017 on the mandatory vaccinations.

Ann Ig 2019 Mar-Apr;31(2 Supple 1):54-64

Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, University of Messina, Italy.

The National Plan for Vaccine Prevention 2017-2019 has expanded the vaccination offer including new vaccines, enlarging the target population and introducing for the first time in Italy a life-course approach to vaccination. A "lifetime immunization schedule" is aimed to reduce the burden and the related costs of vaccine-preventable diseases through effective vaccination programs. However, to counteract the national steady downward trend in the uptake of vaccinations that caused a drop of the vaccination coverage below the 95% threshold to allow herd immunity, it was decided to make 10 vaccinations mandatory by the law 119/2017. Read More

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http://dx.doi.org/10.7416/ai.2019.2277DOI Listing
April 2019
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Trends and spatial distribution of MMR vaccine coverage in Brazil during 2007-2017.

Vaccine 2019 Apr 12. Epub 2019 Apr 12.

Post-Graduation Program in Health Sciences, University of Brasília, Brasília-DF, Brazil.

We analyzed the time trends and spatial distribution of MMR vaccine coverage in Brazil during 2007-2017. In early 2018, a measles outbreak started in the North region of Brazil, reaching 11 of the 27 federal units by January 24, 2019. In this period, 10,302 cases were confirmed. Read More

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http://dx.doi.org/10.1016/j.vaccine.2019.04.019DOI Listing
April 2019
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Battery Powered Portable Thermal Cycler for Continuous-Flow Polymerase Chain Reaction Diagnosis by Single Thermostatic Thermoelectric Cooler and Open-Loop Controller.

Authors:
Di Wu Wenming Wu

Sensors (Basel) 2019 Apr 3;19(7). Epub 2019 Apr 3.

Changchun Institute of Optics, Fine Mechanics and Physics (CIOMP), Chinese Academy of Sciences, Changchun 130000, China.

Temperature control is the most important and fundamental part of a polymerase chain reaction (PCR). To date, there have been several methods to realize the periodic heating and cooling of the thermal-cycler system for continuous-flow PCR reactions, and three of them were widely used: the thermo-cycled thermoelectric cooler (TEC), the heating block, and the thermostatic heater. In the present study, a new approach called open-loop controlled single thermostatic TEC was introduced to control the thermal cycle during the amplification process. Read More

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http://dx.doi.org/10.3390/s19071609DOI Listing
April 2019
4 Reads

The MMR Vaccine and Autism.

Annu Rev Virol 2019 Apr 15. Epub 2019 Apr 15.

Immunization Safety Office, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30329, USA; email:

Autism is a developmental disability that can cause significant social, communication, and behavioral challenges. A report published in 1998, but subsequently retracted by the journal, suggested that measles, mumps, and rubella (MMR) vaccine causes autism. However, autism is a neurodevelopmental condition that has a strong genetic component with genesis before one year of age, when MMR vaccine is typically administered. Read More

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http://dx.doi.org/10.1146/annurev-virology-092818-015515DOI Listing
April 2019
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[A study on measles and rubella antibody level in 319 pairs of mothers and infants in Songjiang District of Shanghai].

Zhonghua Yu Fang Yi Xue Za Zhi 2019 Apr;53(4):388-393

Immunoprophylaxis Department, Songjiang District Center for Disease Control and Prevention, Shanghai 201620, China.

To explore serum levels of measles and rubella IgG antibodies among mothers and infants. According to the inclusion and exclusion criteria, we selected 319 puerperae and their infants in maternal hospitals of Songjiang district November 2016 to February 2017, venous blood were collected and serum measles and rubella IgG antibodies were measured using ELISA. To study the correlation between the level of measles and rubella antibodies in infants and mothers' by using the Spearman's correlation analysis. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0253-9624.2019.04.011DOI Listing
April 2019
1 Read

The rash with maculopapules and fever in children.

Clin Dermatol 2019 Mar - Apr;37(2):119-128. Epub 2018 Dec 5.

Dermatology Department, University of CT Health Center, Farmington, Connecticut, USA. Electronic address:

Several medical conditions can cause children to present with fever and a maculopapular rash Although some presentations are benign, others may be medical emergencies, which warrant a prompt diagnosis. We review some of the more common causes of fever and maculopapular dermatitirs, rash including infectious processes (roseola; rubeola; rubella; parvovirus B19; hand, foot, and mouth disease; scarlet fever; meningococcemia; Epstein-Barr virus infection), hypersensitivity reactions (exanthematous drug reactions), and vasculitis syndromes (Kawasaki disease). We have included a diagnostic algorithm to facilitate rapid identification of the etiology of the rash and fever. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0738081X183025
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http://dx.doi.org/10.1016/j.clindermatol.2018.12.005DOI Listing
December 2018
3 Reads

The rash with maculopapules and fever in adults.

Clin Dermatol 2019 Mar - Apr;37(2):109-118. Epub 2018 Dec 5.

Dermatology Department, University of CT Health Center, Farmington, Connecticut, USA. Electronic address:

There is a broad differential diagnosis for the presentation of fever and maculopapular rash in an adult. Although some causative conditions are benign, others are medical emergencies that require prompt diagnosis. We describe various conditions that result in a fever and maculopapular rash in adults. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2018.12.004DOI Listing
December 2018
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Highly affordable vaccines are critical for our continued efforts to reduce global childhood mortality.

Hum Vaccin Immunother 2019 Apr 11. Epub 2019 Apr 11.

a Max Planck Institute for Infection Biology , Berlin.

Infectious diseases remain a major health threat, not only in resource-poor countries but also in pockets of poverty within middle-income and sometimes high-income countries. Whilst strong research and development for novel vaccines are urgently needed, equal care needs to be taken that current vaccines are produced at affordable prices so that universal childhood immunization will be accomplished. The Serum Institute of India (SII) has become the largest producer of affordable vaccines. Read More

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http://dx.doi.org/10.1080/21645515.2019.1605817DOI Listing
April 2019
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Rubella (German measles) revisited.

Hong Kong Med J 2019 Apr 10;25(2):134-141. Epub 2019 Apr 10.

Department of Pediatric Institute, Kuala Lumpur General Hospital, Malaysia.

Rubella is generally a mild and self-limited disease in children. During pregnancy, rubella can have potentially devastating effects on the developing fetus. Postnatal rubella is transmitted primarily by inhalation of virus-laden airborne droplets or direct contact with infected nasopharyngeal secretions. Read More

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http://dx.doi.org/10.12809/hkmj187785DOI Listing
April 2019
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A step beyond the hygiene hypothesis-immune-mediated classes determined in a population-based study.

BMC Med 2019 Apr 9;17(1):75. Epub 2019 Apr 9.

Department of Psychiatry, Center for Research in Psychiatric Epidemiology and Psychopathology, Lausanne University Hospital, Prilly, Switzerland.

Background: Comorbidity patterns of childhood infections, atopic diseases, and adverse childhood experiences (ACE) are related to immune system programming conditions. The aim of this study was to make a step beyond the hygiene hypothesis and to comprehensively classify these patterns with latent class analysis (LCA). A second aim was to characterize the classes by associations with immunological, clinical, and sociodemographic variables. Read More

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http://dx.doi.org/10.1186/s12916-019-1311-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454751PMC
April 2019
1 Read
7.249 Impact Factor

Safety and seropositivity after live attenuated vaccine in adult patients receiving hematopoietic stem cell transplantation.

Biol Blood Marrow Transplant 2019 Apr 5. Epub 2019 Apr 5.

Department of Medicine and Biosystemic Science, Graduate School of Medical Science, Kyushu University, Fukuoka. Electronic address:

Vaccination against vaccine-preventable diseases (VPDs) is highly recommended for hematopoietic stem cell transplantation (HSCT) recipients by several guidelines; however, the safety and seropositivity after live attenuated vaccines remain unclear in adult HSCT recipients. We analyzed titers of antibodies against measles, rubella, mumps, and varicella zoster virus (VZV) from Japanese adult patients who underwent allogeneic HSCT (allo-HSCT) (n = 74), autologous HSCT (auto-HSCT) (n = 39), or chemotherapy (n = 93). The seropositive rates for measles, rubella, mumps, and VZV in allo-HSCT recipients were 20. Read More

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http://dx.doi.org/10.1016/j.bbmt.2019.04.006DOI Listing
April 2019
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The Impact of Recent Rubella Vaccine Introduction in 5 Countries in The African Region.

J Immunol Sci 2018 Jul;Suppl(16):108-112

WHO Inter-country Support Team for East and Southern Africa, Harare, Zimbabwe.

The World Health Organization (WHO) recommends that countries introduce rubella containing vaccines (RCVs) to reduce rubella circulation and the occurrence of congenital rubella syndrome (CRS). As of June 2017, a total of 18 countries have already introduced or are in the process of introducing RCV in routine child vaccination programs. RCV introduction during 2013 - 2014 in five countries in the Region resulted in a reduction of rubella incidence of 48% to 96% in the post-introduction period as compared to the average incidence in the years before introduction. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446993PMC

Congenital Rubella Syndrome in The African Region - Data from Sentinel Surveillance.

J Immunol Sci 2018 Aug;Suppl:146-150

WHO Regional Office for Africa. Brazzaville, Congo.

Introduction: Rubella is a mild febrile rash illness caused by the rubella virus. The most serious consequence of rubella is congenital rubella syndrome (CRS), which occurs if the primary rubella infection occurs during early pregnancy, with subsequent infection of the placenta and the developing fetus.

Methods: WHO supported countries to set up sentinel surveillance for CRS using standard case definitions, protocols, and case classification scheme. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446990PMC

Performance of National Measles Case-Based Surveillance Systems in The WHO African Region. 2012 - 2016.

J Immunol Sci 2018 Aug;Suppl:130-134

WHO Regional Office for Africa, Brazzaville, Congo.

Case based surveillance for measles is implemented in the African Region integrated with Acute Flaccid Paralysis (AFP) surveillance. In 2011, the Region adopted a measles elimination goal to be achieved by 2020, which included coverage, incidence and surveillance performance targets. We reviewed measles case-based surveillance data and surveillance performance from countries in the African Region for the years 2012 - 2016. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446992PMC
August 2018
1 Read

Neuropathological Findings in a Case of IFIH1-Related Aicardi-Goutières Syndrome.

Pediatr Dev Pathol 2019 Apr 5:1093526619837797. Epub 2019 Apr 5.

4 Departments of Pathology, Neurology, Neurosurgery, University of Colorado, Aurora, Colorado.

Aicardi-Goutières syndrome (AGS) is a rare syndrome characterized by calcification, diffuse demyelination, and variable degree of brain atrophy. The syndrome is genetically heterogeneous with mutations in 7 genes, including TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR1, and IFIH1 (interferon-induced helicase c domain-containing protein 1) associated with the syndrome, so far. These mutations lead to the overproduction of α-interferon within the central nervous system. Read More

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http://dx.doi.org/10.1177/1093526619837797DOI Listing
April 2019
4 Reads

The risk factors of exposure to rubella among pregnant women in Zaria 2013.

Pan Afr Med J 2019 21;32(Suppl 1). Epub 2019 Jan 21.

Ahmadu Bello University, Zaria, Kaduna State, Nigeria.

Introduction: rubella virus usually causes a mild disease, but maternal infection early in pregnancy often leads to birth defects known as congenital rubella syndrome (CRS). Rubella remains poorly controlled in Africa despite being a vaccine preventable disease. The objective of this study was to determine the risk factor of expose of rubella and prevalence of rubella IgG antibodies among pregnant women in Zaria. Read More

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http://dx.doi.org/10.11604/pamj.supp.2019.32.1.13335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441472PMC
April 2019
1 Read

A case of immune-mediated type 1 diabetes mellitus due to congenital rubella ınfection.

Ann Pediatr Endocrinol Metab 2019 Mar 31;24(1):68-70. Epub 2019 Mar 31.

Child and Adolescent Psychiatry Unit, Dokuz Eylul University Hospital, Izmir, Turkey.

Congenital rubella infection is a transplacental infection that can cause intrauterine growth retardation, cataracts, patent ductus arteriosus, hearing loss, microcephaly, thrombocytopenia, and severe fetal injury. It has been shown that type 1 diabetes mellitus develops in 12%-20% of patients with congenital rubella infection, and disorders in the oral glucose tolerance test is observed in 40% of patients. No biochemical or serological markers exist which could indicate that type 1 diabetes was caused by a congenital rubella infection. Read More

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http://dx.doi.org/10.6065/apem.2019.24.1.68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449622PMC

Seroprevalence of Measles in Healthcare Workers in South Korea.

Infect Chemother 2019 Mar;51(1):58-61

Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

There are only limited data regarding the seroprevalence of measles of healthcare workers (HCWs) in Korea. We evaluated the seroprevalence of measles in HCWs in a tertiary care hospital in Korea. A total of 7,411 HCWs born from 1952 to 1995 underwent antibody test. Read More

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http://dx.doi.org/10.3947/ic.2019.51.1.58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446017PMC
March 2019
5 Reads

Genomic signature of early T-cell response is associated with lower antibody titer threshold for sterilizing immunity.

Antiviral Res 2019 Mar 30;166:35-41. Epub 2019 Mar 30.

Viral Research and Experimental Medicine Centre @ SingHealth-Duke NUS, Singapore; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore; Department of Infectious Diseases, Singapore General Hospital, Singapore. Electronic address:

Vaccination is an effective approach to reduce disease burden. High vaccination coverage blocks pathogen transmission to ensure herd immunity. However, the concept of herd immunity assumes that vaccinated individuals cannot be infected and mediate silent pathogen transmission. Read More

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http://dx.doi.org/10.1016/j.antiviral.2019.03.013DOI Listing
March 2019
3 Reads

Enhancing preparedness against rubella at the workplace: proactive prevention efforts by the Tokyo Metropolitan Government.

Jpn J Infect Dis 2019 Mar 26. Epub 2019 Mar 26.

Infectious Disease Control Section, Health and Safety Division, Bureau of Social Welfare and Public Health, Tokyo Metropolitan Government.

During Japan's 2012-2013 rubella epidemic, most transmission in Tokyo occurred at workplaces, especially among men aged 20 to 49. This tendency was likely related to previous rubella immunization policies that prioritized female adolescents. Since 2015, the Tokyo Metropolitan Government has been promoting a project to prevent rubella and other infectious diseases in workplaces. Read More

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http://dx.doi.org/10.7883/yoken.JJID.2018.167DOI Listing

Diagnosis of congenital/perinatal infections by neonatologists: a national survey.

J Perinatol 2019 Mar 26. Epub 2019 Mar 26.

Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.

Objective: To describe the clinical approach used by neonatologists for diagnosis of congenital/perinatal infections (CPI); no such data currently exist.

Study Design: A national survey regarding the diagnosis of toxoplasma, syphilis, rubella, cytomegalovirus, and herpes simplex virus (HSV) infection in neonates.

Result: We received 553 (11%) responses. Read More

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http://dx.doi.org/10.1038/s41372-019-0364-3DOI Listing
March 2019
1 Read

Measles and rubella serosurvey identifies rubella immunity gap in young adults of childbearing age in Zambia: The added value of nesting a serological survey within a post-campaign coverage evaluation survey.

Vaccine 2019 Apr 21;37(17):2387-2393. Epub 2019 Mar 21.

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Background: Serological surveys can potentially complement vaccine coverage surveys, such as post-vaccination campaign coverage evaluation surveys (PCES), by providing direct information on population immunity within and outside the target age range of the mass vaccination campaign. We estimate age-specific population immunity to measles and rubella viruses in Southern Province, Zambia, and assess the value of adding serological data to vaccination coverage estimates by nesting a serological survey within a PCES.

Methods: Dried blood spots (DBS) from fingerprick blood were collected from all individuals ages nine months or older in households participating in the PCES and tested for measles and rubella virus-specific immunoglobulin G (IgG) by enzyme immunoassay (Siemens Enzygnost, Marburg, Germany). Read More

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http://dx.doi.org/10.1016/j.vaccine.2019.02.037DOI Listing
April 2019
5 Reads

Socioeconomic status differences in parental immunization attitudes and child immunization in Canada: Findings from the 2013 Childhood National Immunization Coverage Survey (CNICS).

Prev Med 2019 Mar 20;123:278-287. Epub 2019 Mar 20.

Institut national de santé publique du Quebec, Quebec City, Quebec, Canada.

Childhood vaccination efforts in Canada have been negatively impacted by parents' vaccine hesitancy based on their knowledge, attitudes, and beliefs (KAB) about vaccinations. Less understood is the extent to which child vaccination receipt and KAB vary by parents' socioeconomic status (SES). Analyzing different age groups of children and vaccinations, we examine the extent to which (a) family SES (parent education, household income) is a determinant of Canadian parents' vaccination KAB and child vaccination receipt, and (b) whether SES was indirectly associated with receipt via KAB. Read More

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http://dx.doi.org/10.1016/j.ypmed.2019.03.033DOI Listing
March 2019
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Accelerating measles and rubella elimination through research and innovation - Findings from the Measles & Rubella Initiative research prioritization process, 2016.

Vaccine 2019 Mar 20. Epub 2019 Mar 20.

Accelerated Disease Control and Surveillance Branch, Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA, United States.

The Measles & Rubella Initiative (M&RI) identified five key strategies to achieve measles and rubella elimination, including research and innovation to support cost-effective operations and improve vaccination and diagnostic tools. In 2016, the M&RI Research and Innovation Working Group (R&IWG) completed a research prioritization process to identify key research questions and update the global research agenda. The R&IWG reviewed meeting reports and strategic planning documents and solicited programmatic inputs from vaccination experts at the program operational level through a web survey, to identify previous research priorities and new research questions. Read More

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http://dx.doi.org/10.1016/j.vaccine.2019.01.081DOI Listing
March 2019
2 Reads

Research priorities for accelerating progress toward measles and rubella elimination identified by a cross-sectional web-based survey.

Vaccine 2019 Mar 18. Epub 2019 Mar 18.

Accelerated Disease Control and Surveillance Branch, Global Immunization Division, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Background: In 2012, the World Health Assembly endorsed the Global Vaccine Action Plan (GVAP) that set a target to eliminate measles and rubella in five of the six World Health Organization (WHO) regions by 2020. Significant progress has been made toward achieving this goal through intensive efforts by countries and Measles & Rubella Initiative (M&RI) partners. Accelerating progress will require evidence-based approaches to improve implementation of the core strategies in the Global Measles and Rubella Strategic Plan. Read More

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http://dx.doi.org/10.1016/j.vaccine.2019.02.058DOI Listing
March 2019
4 Reads

Retrospective investigation of antibodies against chikungunya virus (CHIKV) in serum from febrile patients in Mozambique, 2009-2015: Implications for its prevention and control.

PLoS One 2019 21;14(3):e0213941. Epub 2019 Mar 21.

Virus Isolation Laboratory, National Institute of Health, Maputo, Mozambique.

Introduction: Longitudinal data and trends about chikungunya virus (CHIKV) are critical for its control, however in Mozambique very few studies were conducted over 5 decades, between 1957 and 2013. In this study, we retrospectively investigated the occurrence, geographical distribution and trend of anti-CHIKV antibodies between 2009 and 2015 in Mozambique using serum samples from febrile patients.

Methods: A total of 895 serum samples collected from febrile patients for measles and rubella surveillance between 2009 and 2015 in 127 districts of Mozambique were retrospectively tested for IgM and IgG antibodies against CHIKV using a commercially available ELISA. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213941PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428254PMC
March 2019
1 Read

[Elimination of measles in the WHO European Region-challenges persist].

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2019 Apr;62(4):440-449

Programm für durch Impfung vermeidbare Krankheiten und Immunisierung, Weltgesundheitsorganisation, Regionalbüro für Europa, 2100, Kopenhagen, Dänemark.

Background: Measles incidence in the 53 Member States of the World Health Organization (WHO) European Region has fallen dramatically in recent decades. The European Regional Verification Commission for Measles and Rubella Elimination (RVC) verified that 43 member states had interrupted endemic measles transmission for ≥12 months by the end of 2017. However, measles incidence in the region increased sharply in 2018 compared to 2017. Read More

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http://dx.doi.org/10.1007/s00103-019-02920-2DOI Listing
April 2019
1 Read
1.006 Impact Factor

"Get the shot, now!" Disentangling content-related and social cues in physician-patient communication.

Health Psychol Open 2019 Jan-Jun;6(1):2055102919833057. Epub 2019 Mar 11.

Westfälische Wilhelms-Universität Münster, Germany.

We investigated how recipients disentangle social and content-related cues in physicians' communication. We presented 53 students with four different statements by physicians concerning the measles-mumps-rubella vaccine. In a 2 × 2 within-subject design, we manipulated politeness and the use of technical terms. Read More

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http://dx.doi.org/10.1177/2055102919833057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413428PMC
March 2019
2 Reads

Rubella outbreak in the school children, Addis Ababa, Ethiopia: February-April 2018.

BMC Infect Dis 2019 Mar 18;19(1):267. Epub 2019 Mar 18.

Head of Department of Preventive Medicine, School Of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.

Background: Rubella is a vaccine-preventable contagious disease causing an estimated 100,000 children to be born with congenital rubella syndrome each year globally. Studies documented that 18 rubella outbreaks were occurred each year in Ethiopia. Yeka sub-city woreda 13 public health emergency management office reported two measles suspected cases on 8 February, 2018. Read More

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http://dx.doi.org/10.1186/s12879-019-3873-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423871PMC
March 2019
1 Read

Rate of Recurrence of Adverse Events Following Immunization: Results of 19 Years of Surveillance In Quebec, Canada.

Pediatr Infect Dis J 2019 Apr;38(4):377-383

From the Department of Social and Preventive Medicine, Laval University, Quebec, Canada.

Background: While adverse events following immunization (AEFI) are frequent, there are limited data on the safety of reimmunizing patients who had a prior AEFI. Our objective was to estimate the rate and severity of AEFI recurrences.

Methods: We analyzed data from the AEFI passive surveillance system in Quebec, Canada, that collects information on reimmunization of patients who had a prior AEFI. Read More

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http://dx.doi.org/10.1097/INF.0000000000002162DOI Listing
April 2019
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Delivery of Multiple Child and Maternal Health Interventions during Supplementary Immunization Campaign in Rwanda, 2013: Lessons Learnt.

J Immunol Sci 2018 Aug;Suppl(9):63-67

WHO Consultant, WHO Rwanda.

Objective: This paper assesses and describes the estimated coverage of the Measles Rubella (MR) campaign in each district; the national estimate of coverage for Human Papilloma Virus (HPV) vaccination campaign and Vitamin A supplementation simultaneously implemented in 2013.

Methods: We applied descriptive statistics and epidemiological tools to the outcomes of the campaigns to assess the coverage achieved on the different child and maternal health interventions. We also assessed the Adverse Events following Immunization (AEFI) where the evaluation was used at the same time to assess the routine immunization performance coverage for children 12-24 months for all childhood antigens, Tetanus Toxoid coverage among mothers of infants, combined with routine immunization performance evaluation, skilled delivery and bed nets use in Rwanda. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420130PMC
August 2018
1 Read

The use of normal human immunoglobulin (NHIG) for public health purposes in Queensland 2004-2014 and Australia 2014-2016

Commun Dis Intell (2018) 2019 Mar 15;43. Epub 2019 Mar 15.

School of Medicine and Menzies Health Institute Queensland, Griffith University - Metro North Public Health Unit, Metro North Hospital and Health Service

Objective To describe the use of normal human immunoglobulin (NHIG) recommended for public health purposes in Queensland and Australia. Methods Queensland public health unit (PHU) data on notified cases of measles, rubella and hepatitis A from 2004 to 2014 were examined; particularly regarding the number of contacts offered NHIG and the volume recommended per contact. The National Blood Authority (NBA) provided unidentified data from NHIG order form inception (June 2014) through December 2016. Read More

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March 2019
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Transposable elements drive rapid phenotypic variation in .

Proc Natl Acad Sci U S A 2019 Apr 15;116(14):6908-6913. Epub 2019 Mar 15.

State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, 100093 Beijing, China;

Rapid phenotypic changes in traits of adaptive significance are crucial for organisms to thrive in changing environments. How such phenotypic variation is achieved rapidly, despite limited genetic variation in species that experience a genetic bottleneck is unknown. , an annual and inbreeding forb (Brassicaceae), is a great system for studying this basic question. Read More

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http://dx.doi.org/10.1073/pnas.1811498116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452725PMC
April 2019
5 Reads
9.809 Impact Factor

Cutaneous granulomas with primary immunodeficiency in children: a report of 17 new patients and a review of the literature.

J Eur Acad Dermatol Venereol 2019 Mar 14. Epub 2019 Mar 14.

National Reference Centre for Genodermatosis and Rare Diseases of the Skin (MAGEC), Necker-Enfants Malades Hospital, APHP, Paris, France.

Background: Paediatric cutaneous granuloma with primary immunodeficiency (PID) is a rare condition. The physiopathology is unclear, and treatment is challenging. We report on 17 paediatric cases and review the literature. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jdv.15568
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http://dx.doi.org/10.1111/jdv.15568DOI Listing
March 2019
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Measles and rubella seroprevalence in a population of young adult blood donors, France 2013.

Epidemiol Infect 2019 Jan;147:e109

Direction des maladies infectieuses,Santé publique France,Saint-Maurice,France.

As part of the evaluation of the French plan for the elimination of measles and rubella, we conducted a seroprevalence survey in 2013, aimed at updating seroprevalence data for people 18-32 years old. A secondary objective was to estimate measles incidence in this population during the 2009-2011 outbreak, and thus estimate the exhaustiveness of measles mandatory reporting. We used a cross-sectional survey design, targeting blood donors 18-32 years old, living in France since 2009, who came to give blood in a blood collecting site. Read More

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http://dx.doi.org/10.1017/S0950268819000050DOI Listing
January 2019
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Genetic characterisation of Measles virus variants identified during a large epidemic in Milan, Italy, March-December 2017.

Epidemiol Infect 2019 Jan;147:e80

Department of Biomedical Sciences for Health,University of Milan,Milan,Italy.

In 2017, Italy experienced a large measles epidemic with 5408 cases and four deaths. As Subnational Reference Laboratory of the Measles and Rubella surveillance NETwork (MoRoNET), the EpiSoMI (Epidemiology and Molecular Surveillance of Infections) Laboratory (University of Milan) set up rapid and active surveillance for the complete characterisation of the Measles virus (Mv) responsible for the large measles outbreak in Milan and surrounding areas (Lombardy, Northern Italy). The aims of this study were to describe the genetic profile of circulating viruses and to track the pathway of measles transmission. Read More

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http://dx.doi.org/10.1017/S0950268818003606DOI Listing
January 2019
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Aniridia: A Rare Manifestation Of Congenital Rubella Syndrome.

J Ayub Med Coll Abbottabad 2019 Jan-Mar;31(1):131-133

Ayub Medical College Abbottabad, Pakistan.

A foetus affected by a congenital rubella infection can develop congenital rubella syndrome (CRS). Aniridia is the absence of iris, rarely been described in literature in association with CRS, can easily be overlooked, leading to complications e.g. Read More

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March 2019
4 Reads

Social inequities in vaccination coverage among infants and pre-school children in Europe and Australia - a systematic review.

BMC Public Health 2019 Mar 12;19(1):290. Epub 2019 Mar 12.

Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

Background: Herd immunity levels of vaccine uptake are still not reached in some high-income countries, usually in countries with persisting social inequities in uptake. Previous studies have focused on factors within one health care system. This study takes a broader health care systems approach by reviewing the socioeconomic distribution of vaccination coverage on the national level in light of structural and organizational differences of primary care for children. Read More

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http://dx.doi.org/10.1186/s12889-019-6597-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417277PMC
March 2019
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Adult Vaccination Rates in the Mentally Ill Population: An Outpatient Improvement Project.

J Am Psychiatr Nurses Assoc 2019 Mar 13:1078390319831763. Epub 2019 Mar 13.

4 Lacey Eden, MS, FNP, Brigham Young University, Provo, UT, USA.

Background: Adults who suffer with severe and persistent mental illness (SPMI) rarely access medical care to receive preventive vaccines.

Aims: To increase the rate of vaccines among the SPMI population in an outpatient community mental health center (CMHC).

Methods: A review of the literature identified a gap between the general population and SPMI clients in receiving preventive vaccinations. Read More

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http://journals.sagepub.com/doi/10.1177/1078390319831763
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http://dx.doi.org/10.1177/1078390319831763DOI Listing
March 2019
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Erratum: Diagnosis of rubella virus using antigen-conjugated Au@Pt nanorods as nanozyme probe [Corrigendum].

Authors:

Int J Nanomedicine 2019 19;14:1281. Epub 2019 Feb 19.

[This corrects the article on p. 4795 in vol. 13, PMID: 30197515. Read More

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http://dx.doi.org/10.2147/IJN.S202056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391140PMC
February 2019

Impact of the MMR vaccine on the incidence of mumps in the Community of Madrid and evaluation of the effectiveness of the Jeryl-Lynn strain. Years 1998-2016.

Med Clin (Barc) 2019 Mar 8. Epub 2019 Mar 8.

Subdirección General de Epidemiología, Dirección General de Salud Pública de la Comunidad de Madrid, Madrid, España.

Introduction: Mumps is characterised by parotid inflammation and fever and is preventable by vaccination with MMR vaccine. The objective of the study is to assess the impact and effectiveness of the vaccine.

Material And Methods: Cases notified to the Notifiable Disease System between 1998 and 2016 were used for the study. Read More

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http://dx.doi.org/10.1016/j.medcli.2019.01.012DOI Listing
March 2019
7 Reads

Talk to Patients About: Mumps.

Authors:
Sean Price

Tex Med 2019 Mar 1;115(3):47. Epub 2019 Mar 1.

More than 2,000 U.S. mumps cases occurred in 2018. Read More

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March 2019
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Successes and challenges for preventing measles, mumps and rubella by vaccination.

Curr Opin Virol 2019 Feb 7;34:110-116. Epub 2019 Mar 7.

Viral Vaccine Preventable Diseases Branch, Division of Viral Diseases, National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, Atlanta, GA, 30329, USA. Electronic address:

The measles, mumps and rubella (MMR) vaccine has an outstanding safety record and is highly efficacious. High coverage with MMR has led to the elimination of endemic measles, rubella, and congenital rubella syndrome in the US. The biggest challenges to global measles and rubella control and elimination are insufficient vaccination coverage globally and increasing hesitancy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18796257183016
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http://dx.doi.org/10.1016/j.coviro.2019.01.002DOI Listing
February 2019
15 Reads