3,767 results match your criteria Rosacea


A Decade Retrospective Study of Light/Laser Devices in Treating Nasal Rosacea.

J Dermatolog Treat 2019 Feb 7:1-24. Epub 2019 Feb 7.

a Department of Dermatology , No.1 Hospital of China Medical University , Shenyang , China.

Background: Large-scale retrospective studies of light/laser in treating nasal rosacea were lacking.

Objective: The study was aimed to perform a decade retrospection of the patients with nasal rosacea who were treated with light/laser devices.

Methods: Methods: A study between 2008 and 2017 was performed retrospectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/09546634.2019.1580669DOI Listing
February 2019
2 Reads

Assessment of Skin Physiology Change and Safety After Intradermal Injections With Botulinum Toxin: A Randomized, Double-Blind, Placebo-Controlled, Split-Face Pilot Study in Rosacea Patients With Facial Erythema.

Dermatol Surg 2019 Feb 1. Epub 2019 Feb 1.

Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.

Background: Botulinum toxin (BTX) has been used cosmetically with good clinical efficacy and tolerable safety.

Objective: This randomized, double-blind, split-face clinical study aimed to investigate the efficacy and safety of intradermal BTX in patients with rosacea.

Materials And Methods: Twenty-four participants were enrolled and randomly given intradermal injections of BTX and normal saline in both cheeks. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/DSS.0000000000001819DOI Listing
February 2019
2 Reads

Metronidazole loaded nanostructured lipid carriers to improve skin deposition and retention in the treatment of rosacea.

Drug Dev Ind Pharm 2019 Feb 6:1-30. Epub 2019 Feb 6.

a Department of Pharmaceutics , Bombay College of Pharmacy , Mumbai , India.

The objective of the present investigation was to improve the skin deposition and retention of metronidazole (MTZ) in rosacea therapy, by incorporating it into nanostructured lipid carriers (NLCs). The main challenge in this endeavour was the partial hydrophilicity of MTZ, which mandated careful selection of excipients, including solid and liquid lipids, surfactants, and their ratios in combination. NLCs were produced by the phase inversion temperature method and finally converted into a gel for topical application. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/03639045.2019.1569026DOI Listing
February 2019

Noninvasive assessment of subclinical atherosclerosis in patients with rosacea.

G Ital Dermatol Venereol 2019 Feb 4. Epub 2019 Feb 4.

Department of Cardiology, Bozok University School of Medicine, Yozgat, Turkey.

Background: Rosacea is a chronic, inflammatory cutaneous disorder that is characterized by remissions and relapses that commonly occur in patients over the age of 30 years. There have been many studies in literature evaluating the relationship between cardiovascular disease and psoriasis, which is a chronic inflammatory disease, however, there have been very few studies to date evaluating the relationship between rosacea and cardiovascular disease risk.

Methods: The study included 52 consecutive rosacea patients and 52 healthy controls matched for age, gender and body mass index. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.23736/S0392-0488.19.06218-7DOI Listing
February 2019
1 Read

Claudin reduction may relate to an impaired skin barrier in rosacea.

J Dermatol 2019 Feb 4. Epub 2019 Feb 4.

Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.

Rosacea is a chronic inflammatory skin disorder whose pathophysiological mechanism remains largely unknown. Although recent studies have revealed the hypersensitivity of the skin towards chemical, thermal and biological stimuli, there is no direct molecular evidence suggesting the skin barrier is impaired in rosacea. In this study, we demonstrated that the mRNA levels of most claudins (CLDN), the main components of tight junctions determining the major barrier of the paracellular pathway between epithelial cells, were lowered in lesional skin of rosacea patients, especially with erythematotelangiectatic (ETR) and papulopustular (PPR) subtypes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1346-8138.14792DOI Listing
February 2019

Severe Rhinophyma. Tips and Tricks in Carbon Dioxide Laser Decortication.

J Am Acad Dermatol 2019 Jan 30. Epub 2019 Jan 30.

Dermatology Department, Complejo Asistencial Universitario de León, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaad.2019.01.060DOI Listing
January 2019

The mental health burden in acne vulgaris and rosacea: an analysis of the US National Inpatient Sample.

Clin Exp Dermatol 2019 Jan 31. Epub 2019 Jan 31.

Departments of Dermatology, Preventative Medicine, and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Background: Little is known about the mental health (MH) hospitalization among patients with acne and rosacea.

Aims: To determine the MH disorders and cost burden associated with acne and rosacea.

Methods: Data were examined from the 2002-2012 US National Inpatient Sample, comprising a sample of ~20% of all US paediatric and adult hospitalizations (n = 87 053 155 admissions). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ced.13919DOI Listing
January 2019
1 Read

Nuclear Factor Kappa-B is Enriched in Eyelid Specimens of Rosacea: Implications for Pathogenesis and Therapy.

Am J Ophthalmol 2019 Jan 28. Epub 2019 Jan 28.

Department of Molecular and Cellular Physiology, Albany Medical College.

Purpose: To assess the role of nuclear factor kappa-B (NFKB) in cutaneous specimens of rosacea and unaffected tissue METHODS: Immunohistochemical staining was performed for the activated, phosphorylated variant of NFKB (pNFKB) in eyelid specimens of rosacea (n = 12) and normal, healthy tissue (n = 12). The numbers of positively-staining cells/40x microscopic field were counted across five consecutive fields. Additionally, quantitative western blotting was carried out for pNFKB and NFKB in specimens of rosacea (n = 15) and normal controls (n = 14). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2019.01.018DOI Listing
January 2019

A Novel Night Moisturizer Enhances Cutaneous Barrier Function in Dry Skin and Improves Dermatological Outcomes in Rosacea-prone Skin.

J Clin Aesthet Dermatol 2018 Dec 1;11(12):11-17. Epub 2018 Dec 1.

Dr. Santoro is with Galderma Research and Development in Egerkingen, Switzerland.

We assessed whether Cetaphil Redness Control Night Cream (CRCNC; Galderma Laboratories, Fort Worth, Texas) improves electrical capacitance (EC) and transepidermal water loss (TEWL) in healthy subjects with dry skin and determined efficacy and tolerability in subjects with rosacea. The present study included two independent, open-label investigations: in the first, EC and TEWL were measured at baseline and at two, four, eight, and 24 hours after one application of CRCNC to dry skin; in the second, an evaluation of once-daily CRCNC application for 22 days using a chromameter, image analysis, and trained rater was performed, with patient evaluations at baseline and Days 1, 8, and 22 collected. The first study enrolled 20 subjects (13 women; mean age: 45 years). Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334838PMC
December 2018

Clinical and erythema-directed imaging evaluation of papulo-pustular rosacea with topical ivermectin: a 32 weeks duration study.

J Dermatolog Treat 2019 Jan 20:1-5. Epub 2019 Jan 20.

a Dermatology Clinic , University of Catania , Catania , Italy.

Background: Ivermectin (IVM) 1% cream represents an emerging therapy for papulo-pustular rosacea (PPR) and erythema-directed photography is a useful tool for evaluation of patient's erythema.

Objective: The aim of our study was to assess the efficacy of IVM in PPR in achieving clear status at 8 weeks or at 20 weeks followed by respectively 24 and 12 weeks follow-up, using clinical/instrumental evaluation.

Methods: Twenty patients with PPR were instructed to apply IVM for 8 weeks. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/09546634.2019.1572860DOI Listing
January 2019
1 Read

Sarecycline: First Global Approval.

Authors:
Emma D Deeks

Drugs 2019 Jan 18. Epub 2019 Jan 18.

Springer, Private Bag 65901, Mairangi Bay, Auckland, 0754, New Zealand.

Sarecycline (Seysara™) is an oral, once-daily, tetracycline-class drug for which a tablet formulation is approved in the USA for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients aged ≥ 9 years. The drug was developed by Paratek and Allergen and later acquired by Almirall S.A. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40265-019-1053-4DOI Listing
January 2019

Botulinum toxin blocks mast cells and prevents rosacea like inflammation.

J Dermatol Sci 2019 Jan 28;93(1):58-64. Epub 2018 Dec 28.

Department of Dermatology, University of California, San Diego, CA, USA. Electronic address:

Background: Rosacea is a chronic inflammatory skin condition whose etiology has been linked to mast cells and the antimicrobial peptide cathelicidin LL-37. Individuals with refractory disease have demonstrated clinical benefit with periodic injections of onabotulinum toxin, but the mechanism of action is unknown.

Objectives: To investigate the molecular mechanism by which botulinum toxin improves rosacea lesions. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09231811183045
Publisher Site
http://dx.doi.org/10.1016/j.jdermsci.2018.12.004DOI Listing
January 2019
2 Reads

Therapeutic uses of metronidazole and its side effects: an update.

Eur Rev Med Pharmacol Sci 2019 Jan;23(1):397-401

Área Académica de Medicina, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Circuito Ex Hacienda, Pachuca de Soto Hidalgo, México.

Objective: Metronidazole is an antibiotic widely used in different medical conditions such as trichomoniasis, amoebiasis, and giardiasis among others. Its use has been associated with toxicity; however, it is not well characterized. In this review, we discuss the different therapeutic uses of metronidazole and its side effects in order to aid future investigation in this field. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.26355/eurrev_201901_16788DOI Listing
January 2019
2 Reads

Relationship between rosacea and dietary factors: A multicenter retrospective case-control survey.

J Dermatol 2019 Jan 18. Epub 2019 Jan 18.

Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.

Although patients with rosacea often consult dermatologists for dietary factors that might be related to their skin disorders, few studies have been conducted to research the relationship between rosacea and dietary factors. The purpose of this study was to evaluate the potential relationship between rosacea and diet among the large Chinese population with rosacea, which would provide dietary guidelines for patients with rosacea. A multicenter case-control study was conducted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1346-8138.14771DOI Listing
January 2019
1 Read
2.354 Impact Factor

Rosacea: Relative risk versus absolute risk of malignant comorbidities.

J Am Acad Dermatol 2019 Jan 14. Epub 2019 Jan 14.

Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Pathology, Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, North Carolina. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaad.2019.01.013DOI Listing
January 2019

[Idiopathic facial aseptic granuloma: A case report].

Arch Argent Pediatr 2019 02;117(1):e56-e58

Dermatología, carrera de posgrado en Dermatología de la Universidad Católica de Córdoba, Hospital Privado Universitario de Córdoba.

Idiopathic facial aseptic granuloma is a childhood condition characterized by asymptomatic erythematous-violaceous nodules, often confused with abscesses. Its pathogenesis is unknown, but some authors have postulated its relationship with infantile rosacea. We present a case of a patient with a clinical diagnosis of idiopathic facial aseptic granuloma, with ocular involvement and a good response to oral metronidazole treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5546/aap.2019.e56DOI Listing
February 2019
1 Read

Exploring the potential for rosacea therapeutics of siRNA dispersion in topical emulsions.

Exp Dermatol 2019 Jan 16. Epub 2019 Jan 16.

Umbed Pharmaceuticals, Frederiksberg, Denmark.

Rosacea is a prevalent skin condition dependent on the individual genetic profile. The current pharmacological management of this condition is mostly based on small molecule drugs predominately effective in ameliorating the inflammatory condition. Emerging molecular approaches could present an opportunity for managing rosacea conditions at transcriptomic level, and in the future allow personalized approaches. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/exd.13881DOI Listing
January 2019

Trends in Oral Antibiotic Prescription in Dermatology, 2008 to 2016.

JAMA Dermatol 2019 Jan 16. Epub 2019 Jan 16.

Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia.

Importance: Dermatologists prescribe more oral antibiotic courses per clinician than any other specialty, and this use puts patients at risk of antibiotic-resistant infections and antibiotic-associated adverse events.

Objective: To characterize the temporal trends in the diagnoses most commonly associated with oral antibiotic prescription by dermatologists, as well as the duration of this use.

Design, Setting, And Participants: Repeated cross-sectional analysis of antibiotic prescribing by dermatologists from January 1, 2008, to December 31, 2016. Read More

View Article

Download full-text PDF

Source
http://archderm.jamanetwork.com/article.aspx?doi=10.1001/jam
Publisher Site
http://dx.doi.org/10.1001/jamadermatol.2018.4944DOI Listing
January 2019
2 Reads

[Advancement in phodynamic therapy for non-neoplastic skin diseases].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Dec;43(12):1380-1383

Department of Cardiovascular Surgery, Second Xiangya Hospital, Central South University, Changsha 410011, China.

Photodynamic therapy is mainly used in dermatology to treat skin tumors, precancerous lesions, and condyloma acuminatum. Due to its excellent tissue selectivity, easy operation and good cosmetic effect, it has been gradually applied to the treatment of various non-neoplastic skin diseases, such as verruca acuminata, acne, rosacea, chronic skin ulcer, fungal diseases, keloid, and so on. Here is the review on the advancement in photodynamic therapy for non-neoplastic skin diseases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11817/j.issn.1672-7347.2018.12.016DOI Listing
December 2018
1 Read

Clinical effectiveness of novel rosacea therapies.

Curr Opin Pharmacol 2019 Jan 10;46:14-18. Epub 2019 Jan 10.

Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC, United States.

Rosacea is a common inflammatory skin disease that is difficult to manage because of the unknown etiology and due to its variable manifestations. These facts and the few new available treatment options make it difficult to select a really effective treatment. This review aims to assess the efficacy and safety of novel treatment options for rosacea. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S14714892183011
Publisher Site
http://dx.doi.org/10.1016/j.coph.2018.12.001DOI Listing
January 2019
4 Reads

Classifying signs and symptoms of dry eye disease according to underlying mechanism via the Delphi method: the DIDACTIC study.

Br J Ophthalmol 2019 Jan 12. Epub 2019 Jan 12.

Department of Ophthalmology, APHP-Bichat-Claude-Bernard Hospital, Paris, France.

Background/aims: Dry eye disease (DED) is categorised by pathophysiology as aqueous deficient dry eye (ADDE), evaporative dry eye (EDE) or mixed. Treatment should be tailored to DED pathophysiology, but this is challenging to determine. This Delphi consultation aimed to categorise and weight signs and symptoms to help identify the evaporative or aqueous deficient DED origin. Read More

View Article

Download full-text PDF

Source
http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2018-3125
Publisher Site
http://dx.doi.org/10.1136/bjophthalmol-2018-312581DOI Listing
January 2019
5 Reads

Recent advances in understanding and managing rosacea.

F1000Res 2018 3;7. Epub 2018 Dec 3.

Department of Dermatology and Venereology, Hamad Medical Corporation, Doha, Qatar.

Rosacea is a common chronic inflammatory skin disease of the central facial skin and is of unknown origin. Currently, two classifications of rosacea exist that are based on either "preformed" clinical subtypes (erythematotelangiectatic, papulopustular, phymatous, and ocular) or patient-tailored analysis of the presented rosacea phenotype. Rosacea etiology and pathophysiology are poorly understood. Read More

View Article

Download full-text PDF

Source
https://f1000research.com/articles/7-1885/v1
Publisher Site
http://dx.doi.org/10.12688/f1000research.16537.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281021PMC
December 2018
4 Reads

Melkersson-Rosenthal syndrome: a case report of a rare disease with overlapping features.

Allergy Asthma Clin Immunol 2019 5;15. Epub 2019 Jan 5.

2Department of Neuroscience, Division of Dentistry, University of Padua, Via Giustiniani 2, 35128 Padua, Italy.

Background: Melkersson-Rosenthal syndrome (MRS) is a rare, neuro-mucocutaneous disease which presents as orofacial swelling, facial palsy and fissured tongue. These symptoms may occur simultaneously or, more frequently, with a oligosymptomatic or monosymptomatic pattern. Swelling, that is the most common initial finding, may mimic hereditary or acquired angioedema, a disorder caused by histamine or bradykinin-mediated plasma-leakage affecting subcutaneous and/or submucosal tissue. Read More

View Article

Download full-text PDF

Source
https://aacijournal.biomedcentral.com/articles/10.1186/s1322
Publisher Site
http://dx.doi.org/10.1186/s13223-018-0316-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320604PMC
January 2019
5 Reads

Nickel Sensitivity In Rosacea Patients: A Prospective Case Control Study.

Authors:
Nurşad Çifci

Endocr Metab Immune Disord Drug Targets 2019 Jan 1. Epub 2019 Jan 1.

Department of Dermatology, Kocaeli Derince Education and Research Hospital, Kocaeli. Turkey.

Background: Rosacea is a frequently seen chronic disease that allergens, some foods and beverages are known to trigger symptoms of rosacea.

Objective: We aimed to assess if nickel sensivity is more common in rosacea patients than normal population.

Method: Fourty patients with rosacea and 40 healthy age and sex matched volunteers were included in the study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1871530319666190101120437DOI Listing
January 2019
4 Reads

Misuse of veterinary wormers in self-medication of rosacea and scabies.

Br J Dermatol 2018 Dec 30. Epub 2018 Dec 30.

Department of Dermatology, Beaumont Hospital, Dublin 9, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjd.17540DOI Listing
December 2018
2 Reads

Epidemiology of benign essential blepharospasm: A nationwide population-based retrospective study in Taiwan.

PLoS One 2018 26;13(12):e0209558. Epub 2018 Dec 26.

Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

Importance: This study provides a nationwide, population-based data on the incidence of benign essential blepharospasm in Asian adults.

Background: To describe the incidence, patient demographics, and risk factors associated with benign essential blepharospasm.

Design: Population-based retrospective study. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209558PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306223PMC
December 2018
10 Reads

Insights into the role of endoplasmic reticulum stress in skin function and associated diseases.

FEBS J 2019 Jan;286(2):413-425

Department of Dermatology, School of Medicine, University of California, San Francisco, CA, USA.

Endoplasmic reticulum (ER) stress is a mechanism that allows the protection of normal cellular functions in response to both internal perturbations, such as accumulation of unfolded proteins, and external perturbations, for example redox stress, UVB irradiation, and infection. A hallmark of ER stress is the accumulation of misfolded and unfolded proteins. Physiological levels of ER stress trigger the unfolded protein response (UPR) that is required to restore normal ER functions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/febs.14739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362265PMC
January 2019

Interventions for rosacea based on the phenotype approach: An updated systematic review including GRADE assessments.

Br J Dermatol 2018 Dec 26. Epub 2018 Dec 26.

Independent researcher and consumer referee, Quebec, Canada.

Background: Rosacea is a common chronic facial dermatosis. Classification of rosacea has evolved from subtyping to phenotyping.

Objectives: Updating our systematic review on interventions for rosacea. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjd.17590DOI Listing
December 2018
1 Read

Tranexamic acid ameliorates rosacea symptoms through regulating immune response and angiogenesis.

Int Immunopharmacol 2019 Feb 19;67:326-334. Epub 2018 Dec 19.

Department of Dermatology, Xiangya Hospital, Central South University, 410008 Changsha, Hunan, China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Central South University, 410008 Changsha, Hunan, China. Electronic address:

Rosacea is a chronic inflammatory cutaneous disease characterized by immune system anomalies and vascular hyperreactivity. Recently, therapy of rosacea has improved substantially with the approval of Tranexamic acid (TXA), an antifibrinolytic agent. However, we know little about the underlying mechanism. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.intimp.2018.12.031DOI Listing
February 2019
1 Read

Systemic comorbidities associated with rosacea: a multicentric retrospective observational study.

Int J Dermatol 2018 Dec 21. Epub 2018 Dec 21.

Faculty of Medicine, Department of Dermatology, Celal Bayar University, Manisa, Turkey.

Background: Once considered a disorder limited to the skin, rosacea is now known to be associated with systemic disorders. The aim of this study was to determine what systemic comorbidities accompany rosacea and to determine the relationship between the type, severity, and duration of rosacea, and the presence of and type of systemic comorbidities.

Methods: This retrospective multicenter study was conducted by the Turkish Society of Dermatology Acne Study Group. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ijd.14353DOI Listing
December 2018
1 Read

Morbihan disease: treatment difficulties and diagnosis: a case report.

Pan Afr Med J 2018 26;30:226. Epub 2018 Jul 26.

Department of Dermatology and Venereology, Ibn Rochd University Hospital, Casablanca, Morocco.

Morbihan disease (MD) is a rare entity. Its nosography is unclear and its therapeutic management is difficult. We report a new case of MD. Read More

View Article

Download full-text PDF

Source
http://www.panafrican-med-journal.com/content/article/30/226
Publisher Site
http://dx.doi.org/10.11604/pamj.2018.30.226.14440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295304PMC
January 2019
13 Reads

Fluorescent light energy: Treating rosacea subtypes 1, 2, and 3.

Clin Case Rep 2018 Dec 25;6(12):2385-2390. Epub 2018 Oct 25.

FB Dermatology Denmark Limited Aps. Ballerup Denmark.

Kleresca® biophotonic platform utilizing fluorescent light energy effectively decreased the inflammatory and erythematous reaction common in rosacea subtypes 1, 2, and 3. Kleresca® may be considered as a single treatment for rosacea, targeting multiple features, or combined with invasive methods for an enhanced normalizing and healing profile of the skin. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ccr3.1891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293188PMC
December 2018

Complete Decongestive Therapy Is an Option for the Treatment of Rosacea Lymphedema (Morbihan Disease): Two Cases.

Phys Ther 2018 Dec 18. Epub 2018 Dec 18.

Department of Dermatology, Ankara University.

Background And Purpose: Morbihan disease, also known as rosacea lymphedema, is a rare persistent form of lymphedema that is associated with the disease of rosacea. Even though acne rosacea responds well to standard medical treatment, the lymphedema component of the disease is resistant to both medical and surgical therapy. Complete decongestive therapy (CDT) may be considered as a conservative alternative option for treatment of rosacea lymphedema. Read More

View Article

Download full-text PDF

Source
https://academic.oup.com/ptj/advance-article/doi/10.1093/ptj
Publisher Site
http://dx.doi.org/10.1093/ptj/pzy155DOI Listing
December 2018
6 Reads

Nested Polymerase Chain Reaction and Cutaneous Tuberculosis.

Am J Dermatopathol 2018 Nov 27. Epub 2018 Nov 27.

Unidad de Investigación Médica en Inmunoquímica, Hospital de Especialidades, Centro Médico Nacional SXXI, IMSS, Mexico City, México.

The role of Mycobacterium tuberculosis in the etiology and pathogenesis of cutaneous tuberculosis is controversial because of the difficulties associated with demonstrating the presence of these mycobacteria in tuberculid cutaneous lesions by routinely available microbiological and histological techniques. In this study, we aimed to demonstrate the presence of M. tuberculosis in cutaneous tuberculosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/DAD.0000000000001315DOI Listing
November 2018
8 Reads

Dietary supplementation with turmeric polyherbal formulation decreases facial redness: a randomized double-blind controlled pilot study.

J Integr Med 2019 Jan 22;17(1):20-23. Epub 2018 Nov 22.

Department of Dermatology, University of California, Davis, Sacramento, CA 95816, USA; Department of Biological Sciences, California State University, Sacramento, CA 95819, USA; Pacific Skin Institute, Sacramento, CA 95815, USA. Electronic address:

Background: Facial redness is multifactorial in nature and may be a sign of many different conditions, including rosacea, photo damage and flushing. Herbal medicines have been used for thousands of years to treat a variety of dermatological conditions. Turmeric (Curcuma longa) and its constituents have been shown to mediate dilation and constriction of peripheral arterioles and have demonstrated anti-oxidant, anti-inflammatory and wound-healing properties. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.joim.2018.11.004DOI Listing
January 2019
1 Read

Topical Oxymetazoline Cream 1.0% for Persistent Facial Erythema Associated With Rosacea: Pooled Analysis of the Two Phase 3, 29-Day, Randomized, Controlled REVEAL Trials

J Drugs Dermatol 2018 Nov;17(11):1201-1208

Background: Rosacea is a chronic dermatologic condition with limited treatment options. Methods: Data were pooled from two identically designed phase 3 trials. Patients with moderate to severe persistent erythema of rosacea were randomized to receive oxymetazoline cream 1. Read More

View Article

Download full-text PDF

Source
November 2018
15 Reads

Use of an Alternative Method to Evaluate Erythema Severity in a Clinical Trial: Difference in Vehicle Response With Evaluation of Baseline and Postdose Photographs for Effect of Oxymetazoline Cream 1.0% for Persistent Erythema of Rosacea in a Phase 4 Study.

Br J Dermatol 2018 Nov 30. Epub 2018 Nov 30.

Allergan plc, Irvine, CA.

Background: Once-daily topical oxymetazoline cream 1.0% significantly reduced persistent facial erythema of rosacea in trials requiring live, static patient assessments.

Objective: To critically evaluate the methodology of clinical trials that require live, static patient assessments by determining whether assessment of erythema is different when reference to the baseline photograph is allowed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjd.17462DOI Listing
November 2018
2 Reads

Rosacea-specific quality of life questionnaire: translation, cultural adaptation and validation for Brazilian Portuguese.

An Bras Dermatol 2018 Nov/Dec;93(6):836-842

Department of Dermatology, Universidade Federal de São Paulo, São Paulo (SP), Brazil.

Background: Brazil does not have a rosacea-specific quality of life questionnaire.

Objectives: translation into Brazilian Portuguese, development of cultural adaptation, and validation of the RosaQoL disease-specific questionnaire for rosacea of any subtype.

Methods: the recommended procedures for translation, cultural adaptation, and validation of an instrument were followed, and three interviews were conducted: baseline; seven to fourteen days after baseline; and at four to six months. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/abd1806-4841.20187192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256224PMC
February 2019
1 Read

Risk of psychiatric disorders in rosacea: A nationwide, population-based, cohort study in Taiwan.

J Dermatol 2019 Feb 22;46(2):110-116. Epub 2018 Nov 22.

Department of Dermatology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Rosacea has been reported to be associated with psychiatric disorders. Nevertheless, a nationwide study of the relationship between rosacea and comorbid psychiatric diseases in an Asian population has not been conducted. The aim of this study was to clarify the role of rosacea in the various psychiatric disorders by using a nationwide database in Taiwan. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1346-8138.14705DOI Listing
February 2019
1 Read

Potassium Iodide for Cutaneous Inflammatory Disorders: A Monocentric, Retrospective Study.

Dermatology 2018 Nov 21:1-7. Epub 2018 Nov 21.

Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.

Objectives: Potassium iodide (KI) is a medication that has been used for decades in dermatology and it is mentioned as a treatment option in all major dermatology textbooks. Yet, there is little recent information on its efficacy. In our study, we wanted to retrospectively evaluate the therapy response to KI in our patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000494614DOI Listing
November 2018
21 Reads

The Spectrum and Sequelae of Acne in Black South Africans Seen in Tertiary Institutions.

Skin Appendage Disord 2018 Oct 30;4(4):301-303. Epub 2018 May 30.

School of Public Health and Nursing, University of KwaZulu-Natal, Durban, South Africa.

Introduction: Acne is a chronic disorder of the pilosebaceous unit affecting all ethnic groups. It remains in the top 5 skin conditions seen worldwide. The paucity of data characterizing acne in South African Blacks led us to the documentation of types and sequelae of acne. Read More

View Article

Download full-text PDF

Source
https://www.karger.com/Article/FullText/488689
Publisher Site
http://dx.doi.org/10.1159/000488689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219215PMC
October 2018
9 Reads

Body Piercing: A National Survey in France.

Dermatology 2019 7;235(1):71-78. Epub 2018 Nov 7.

FIMARAD, Hôpital Necker Enfants Malades, Paris, France.

Background: There are no recent data available in France regarding body piercing (BP).

Objective: We examined the demographics, motivations, quality of life, cutaneous conditions, and cutaneous side effects after BP within the French population.

Methods: A representative sample of 5,000 individuals (aged 15 and over) from the general population responded to a survey online between April and August 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000494350DOI Listing
November 2018
3 Reads

The relationship between inflammatory bowel disease and rosacea over the lifespan: A meta-analysis.

Clin Res Hepatol Gastroenterol 2018 Oct 30. Epub 2018 Oct 30.

School of Nursing, Qingdao University, Qingdao, Shandong, China. Electronic address:

Backgrounds And Aims: It has been argued that the relationship between inflammatory bowel disease (IBD) and rosacea is bi-directional, but this hypothesis has not been explicitly tested. This systematic review examines the bi-directional prospective relationships between IBD and rosacea.

Methods: A comprehensive search through PubMed and EMBASE was undertaken for studies investigating the association between two mainly forms of IBD [ulcerative colitis (UC) and Crohn's disease (CD)] and rosacea published in English until Jan 2018. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S22107401183019
Publisher Site
http://dx.doi.org/10.1016/j.clinre.2018.09.009DOI Listing
October 2018
4 Reads

Association between rosacea severity and relative muscle mass: A cross-sectional study.

J Dermatol 2019 Jan 31;46(1):11-17. Epub 2018 Oct 31.

Department of Dermatology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Rosacea is thought to be associated with factors involved in metabolic syndrome (MetS). Muscle mass has a beneficial role in preventing MetS, but its link to rosacea remains unknown. We sought to investigate the association between rosacea severity and relative skeletal muscle mass. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/1346-8138.14689
Publisher Site
http://dx.doi.org/10.1111/1346-8138.14689DOI Listing
January 2019
22 Reads

[FEATURES OF ROSACEA PATHOGENESIS IN PERIMENOPAUSAL WOMEN].

Georgian Med News 2018 Sep(282):99-102

Tbilisi State Medical University, Department of Dermatology and Venereology, Georgia.

In patients with rosacea, the monitoring of blood melatonin in the menopausal period, as one of the criteria for assessing the severity of the disease, seems appropriate and pathogenetically justified. The aim of this study was determination of blood melatonin, VEGF, IL-8 concentration in perimenopausal period of women suffering by rosacea. 43 to 65 years old 15 women with various clinical manifestations of rosacea, and severe climacteric syndrome were under observation. Read More

View Article

Download full-text PDF

Source
September 2018
10 Reads

Association of Caffeine Intake and Caffeinated Coffee Consumption With Risk of Incident Rosacea in Women.

JAMA Dermatol 2018 Dec;154(12):1394-1400

Department of Dermatology, Warren Alpert Medical School, Brown University, Providence, Rhode Island.

Importance: Caffeine is known to decrease vasodilation and have immunosuppressant effects, which may potentially decrease the risk of rosacea. However, the heat from coffee may be a trigger for rosacea flares. The relationship between the risk of rosacea and caffeine intake, including coffee consumption, is poorly understood. Read More

View Article

Download full-text PDF

Source
http://archderm.jamanetwork.com/article.aspx?doi=10.1001/jam
Publisher Site
http://dx.doi.org/10.1001/jamadermatol.2018.3301DOI Listing
December 2018
7 Reads

The role of phosphodiesterase 4 in the pathophysiology of atopic dermatitis and the perspective for its inhibition.

Exp Dermatol 2019 Jan 12;28(1):3-10. Epub 2018 Dec 12.

Pfizer Inc, Collegeville, Pennsylvania.

Atopic dermatitis (AD) is a highly prevalent, chronic inflammatory skin disease that affects children and adults. The pathophysiology of AD is complex and involves skin barrier and immune dysfunction. Many immune cytokine pathways are amplified in AD, including T helper (Th) 2, Th22, Th17 and Th1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/exd.13808DOI Listing
January 2019
1 Read

Integrating the Integumentary System with the Arts: A Review of Dermatologic Findings in Artwork.

Authors:
Amit Om Anjali Om

J Clin Aesthet Dermatol 2018 Sep 1;11(9):21-27. Epub 2018 Sep 1.

Dr. Om is with the Division of Dermatology at Florida State University in Tallahassee, Florida.

The objectives of this review are to demonstrate that portraits, in their visual reflections of subjects faces and expressions, offer significant representations relevant to the field of dermatology and bring attention to an underappreciated aesthetic of dermatological conditions. The review comprises paintings that purposefully or inadvertently depict dermatological conditions. The findings were substantiated by searching PubMed using the keywords , , and , as well as combinations of these terms. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169602PMC
September 2018
11 Reads

An annotated catalogue of the pygmy grasshoppers of the tribe Scelimenini Bolívar, 1887 (Orthoptera: Tetrigidae) with two new Scelimena species from the Malay Peninsula and Sumatra.

Zootaxa 2018 Sep 25;4485(1):1-70. Epub 2018 Sep 25.

Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia.

Pygmy grasshoppers (Tetrigidae) are a speciose group of complicated taxonomy, with many species requiring clarification on their species boundaries, and more still awaiting discovery. Two new species of Scelimena Serville, 1838 are described: (1) from S. discalis species group S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11646/zootaxa.4485.1.1DOI Listing
September 2018
1 Read

The toxic edge-A novel treatment for refractory erythema and flushing of rosacea.

Lasers Surg Med 2018 Oct 12. Epub 2018 Oct 12.

Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Purpose: Rosacea is a common, chronic facial skin disease that affects the quality of life. Treatment of facial erythema with intradermal botulinum toxin injection has previously been reported. The primary objective of the study was the safety and efficacy of thermal decomposition of the stratum corneum using a novel non-laser thermomechanical system (Tixel, Novoxel, Israel) to increase skin permeability for Botulinum toxin in the treatment of facial flushing of rosacea. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/lsm.23023
Publisher Site
http://dx.doi.org/10.1002/lsm.23023DOI Listing
October 2018
14 Reads