3,639 results match your criteria Rosacea


[A dog related Demodex spp. infestation in a student: a rare Demodex case].

Mikrobiyol Bul 2018 Apr;52(2):214-220

Selçuk University Faculty of Veterinary, Department of Parasitology, Konya, Turkey.

Demodicosis is an ectoparasitic cutaneous infestation of pilosebaceous unit caused by Demodex mites. Demodex spp. are considered to be pathogenic when they increase in number and infect dermis. Read More

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Cutaneous and Mucosal Manifestations Associated with Celiac Disease.

Nutrients 2018 Jun 21;10(7). Epub 2018 Jun 21.

Dermatology Unit, Hospital Universitario Central de Asturias (HUCA), Avda. de Roma s/n, 33011 Oviedo, Asturias, Spain.

Celiac disease (CD) is an immune-mediated, gluten-induced enteropathy that affects predisposed individuals of all ages. Many patients with CD do not report gastrointestinal symptoms making it difficult to reach an early diagnosis. On the other hand, CD is related to a wide spectrum of extra-intestinal manifestations, with dermatitis herpetiformis (DH) being the best characterized. Read More

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Genome wide analysis of TLR1/2- and TLR4-activated SZ95 sebocytes reveals a complex immune-competence and identifies serum amyloid A as a marker for activated sebaceous glands.

PLoS One 2018 21;13(6):e0198323. Epub 2018 Jun 21.

Unit of Dermatology and Venereology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

Toll-like receptors (TLR) 2 and 4 are active in sebaceous glands and play a central role in the development of acne. Still, there is only limited knowledge on their effect on sebocytes. In this work we performed global gene expression profile analysis with functional clustering of the differentially regulated genes of TLR1/2 (PAM3CSK4)- and TLR4 (lipopolysaccharide [LPS])-activated SZ95 sebocytes. Read More

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June 2018
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Patient Preferences and Therapeutic Satisfaction with Topical Agents for Rosacea: A Survey-Based Study.

Am Health Drug Benefits 2018 Apr;11(2):97-106

Former Vice President, Analysis Group, Montréal, Québec, Canada.

Background: Rosacea is a chronic inflammatory skin disorder that primarily affects the convexities of the central face. Depending on the severity and type of rosacea, physicians may prescribe interventions such as behavioral changes, laser and intense pulsed light, as well as various pharmacologic therapies, including topical agents. The impact of side effects associated with topical treatments for rosacea on patient preferences and treatment satisfaction is not well-documented. Read More

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April 2018
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Topical brimonidine reduces IPL-induced erythema without affecting efficacy: A randomized controlled trial in patients with facial telangiectasias.

Lasers Surg Med 2018 Jun 17. Epub 2018 Jun 17.

Department of Dermatology, Bispebjerg University Hospital, Copenhagen, Denmark.

Background: Laser and intense pulsed light (IPL) are standard symptomatic treatments for superficial telangiectasias, but postoperative erythema, oedema, and pain may prolong downtime.

Objectives: To investigate whether topical brimonidine reduces IPL-induced inflammation in patients with moderate to severe facial telangiectasias.

Methods: A randomized, two-centre, single-blinded, split-face trial on adjuvant brimonidine and air-cooling versus air-cooling alone (control) in 19 patients treated in Denmark (n = 10 patients) and Belgium (n = 9). Read More

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June 2018
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Russian traditional medicine in dermatology.

Clin Dermatol 2018 May - Jun;36(3):325-337. Epub 2018 Mar 13.

Rakhmanov Department of Dermatology and Venereal Diseases at the First Moscow State Sechenov Medical University of the Russian Federation, Moscow, Russia; Institute of Medical and Social Technologies, Postgraduate Medical School, Department of Dermatology, Venereology and Cosmetology, Moscow State University of Food Production, Moscow, Russia; Department of Dermatology, Bedford Hospital, Bedford, UK. Electronic address:

The use of herbal remedies for various medical issues is becoming increasingly commonplace in all fields of medicine, and dermatology is no exception. This review focuses on traditional dermatologic herbal remedies, commonly used in Russia, as the rich array of 11 different plant zones has resulted in a great variety of medicinal plants. Herbal remedies warrant deeper investigation and research, especially due to their active substance content, which may interfere with or reinforce the effect of modern medications, something that medical professionals should be aware of when prescribing treatments. Read More

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March 2018
1 Read

The rapid effect of pulsed dye laser on demodex density of facial skin.

J Cosmet Laser Ther 2018 Jun 8:1-4. Epub 2018 Jun 8.

a Kayseri Health Training and Research Center, Dermatology Clinic , Health Sciences University , Kayseri , Turkey.

Background: Recently, treatment with acaricides, which is aimed at reducing excessive proliferation of demodex mites, has gained popularity due to its providing a significant improvement in the symptoms of diseases, such as rosacea, seborrhoeic dermatitis, and perioral dermatitis. The effect of IPL on demodex mites was reported in skin biopsy specimens in three patients; however, to the best of our knowledge, no study exists to date, which evaluates the effect of pulsed dye laser (PDL) on demodex density (Dd) in larger patient group. We aim here in to observe the Dd before and after PDL therapy with two different skin biopsy techniques. Read More

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Fifteen Minute Test May Save 15% or More on Rosacea Treatment.

J Drugs Dermatol 2018 Jun;17(6):692-693

Rosacea is a common inflammatory skin condition that impacts a large portion of fair-skinned populations. The redness associated with rosacea can be a significant challenge. Brimonidine sulfate and oxymetazoline HCL were both recently approved by the FDA for the management of facial redness. Read More

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The Effect of an Anti-Inflammatory Botanical Cleanser/Night Mask Combination on Facial Redness Reduction.

J Drugs Dermatol 2018 Jun;17(6):671-676

Facial redness is a common difficult to control cosmetic problem representing various phases of rosacea. Using anti-inflammatory/antioxidant botanicals in moisturizer formulations is a possible approach to minimizing the erythema. This research utilized a common facial cleanser, but only applied the botanically based moisturizer to one half face to properly assess efficacy. Read More

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The Efficacy and Safety of Azelaic Acid 15% Foam in the Treatment of Facial Acne Vulgaris.

J Drugs Dermatol 2018 Jun;17(6):641-645

Background: Azelaic acid demonstrates anti-inflammatory, anti-oxidative, anti-comedogenic, and anti-microbial effects. Azelaic acid 20% cream is currently approved for the treatment of acne vulgaris, and azelaic acid 15% foam has recently been approved for rosacea. Given the favorable tolerability profile of foam preparations, it is reasonable to assume that azelaic acid 15% foam could serve as a viable treatment option for facial acne. Read More

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Clinically Relevant Reduction in Persistent Facial Erythema of Rosacea on the First Day of Treatment With Oxymetazoline Cream 1.0.

J Drugs Dermatol 2018 Jun;17(6):621-626

Background: Persistent facial erythema is a clinically challenging feature of rosacea.

Objective: To evaluate persistent erythema reduction on the first day of treatment from pooled data from two pivotal trials of topical oxymetazoline cream 1.0% (oxymetazoline) in persistent facial erythema of rosacea. Read More

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A Biologically Based Approach to Acne and Rosacea.

J Drugs Dermatol 2018 Jun;17(6):611-617

Complementary and alternative medicine (CAM) therapies are increasing in popularity in the field of dermatology. Natural products and holistic approaches are in high demand among patients and research has begun to support their roles in acne and rosacea pathophysiology. In this article, commonly utilized biologically based complementary and alternative therapies for acne and rosacea are reviewed from an evidence-based perspective. Read More

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IL-1α and MMP-9 Tear Levels of Patients with Active Ocular Rosacea before and after Treatment with Systemic Azithromycin or Doxycycline.

Ophthalmic Res 2018 Jun 6:1-6. Epub 2018 Jun 6.

Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Multi-Centric Residency Program in Ophthalmology, Monterrey, Mexico.

Aims: The purpose of this paper was to determine the lacrimal concentration of IL-1α and MMP-9 in patients with active ocular rosacea before and after systemic treatment with azithromycin or doxycycline.

Methods: After 4 weeks of therapy with azithromycin (500 mg/day, 3 days a week PO) or doxycycline (200 mg/day PO), lacrimal samples were analyzed using an enzyme-linked immunosorbent assay multiplex.

Results: There was a significant difference between baseline IL-1α (37. Read More

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June 2018
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Increased expression of IL-33 in rosacea skin and UVB-irradiated and LL-37-treated HaCaT cells.

Exp Dermatol 2018 Jun 6. Epub 2018 Jun 6.

Department of Dermatology, Ewha Womans University College of Medicine, Seoul, Republic of Korea.

Background: Rosacea is one of the most common dermatoses of adults. Although the detailed pathophysiology remains unknown, it is thought that rosacea is caused by a consistently aberrant, innate immune response, and that LL-37 plays an important role. However, involvement of the inflammatory cytokine IL-33 has not yet been studied. Read More

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pH in nature, humans and skin.

Authors:
Ehrhardt Proksch

J Dermatol 2018 Jun 4. Epub 2018 Jun 4.

Department of Dermatology, University of Kiel, Kiel, Germany.

The pH plays an important physiological role in nature and humans. pH varies from 1 to 8 in human organs with tight regulation in blood and epithelia of barrier organs. The physiological pH of the stratum corneum is 4. Read More

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June 2018
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In vitro evaluation of natural thermal mineral waters in human keratinocyte cells: a preliminary study.

Int J Biometeorol 2018 Jun 2. Epub 2018 Jun 2.

Biota Research & Development Center, Sancaktepe, 34785, Istanbul, Turkey.

We aimed to test the anti-inflammatory and angiogenic properties of two different thermal waters at the cellular level in human keratinocyte cells in the present study. Two different thermal waters, thermo-mineral BJ1 (Bursa, Turkey) and oligomineral BG (Bolu, Turkey), were tested in human keratinocyte (HaCaT) cell line. HaCaT cells were incubated for 3 days with thermal waters; RNA isolation was carried out in the treated and untreated cells. Read More

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The Evaluation of Contact Sensitivity with Standard and Cosmetic Patch Test Series in Rosacea Patients.

Ann Dermatol 2018 Jun 23;30(3):290-295. Epub 2018 Apr 23.

Department of Biostatistics, Eskişehir Osmangazi University Faculty of Medicine, Eskisehir, Turkey.

Background: Rosacea is a common dermatosis characterized by erythema, telangiectasia, papules and pustules.

Objective: We aimed to evaluate contact sensitivity in the rosacea patients.

Methods: We included 65 rosacea patients and 60 healthy volunteers in the study. Read More

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June 2018
2 Reads

Applying the phenotype approach for rosacea to practice and research.

Br J Dermatol 2018 May 25. Epub 2018 May 25.

Department of Dermatology, Touro University Nevada, Henderson, NV.

Background: Rosacea diagnosis and classification have evolved since the 2002 National Rosacea Society (NRS) expert panel subtype approach. Several working groups are now aligned to a more patient-centric phenotype approach, based on an individual's presenting signs and symptoms. However, subtyping is still commonplace across the field and an integrated approach is required to ensure widespread progression to the phenotype approach. Read More

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May 2018
4 Reads

Willingness to pay for a cure of low-risk melanoma patients in Germany.

PLoS One 2018 24;13(5):e0197780. Epub 2018 May 24.

Skin Cancer Center, Department of Dermatology, University Hospital Schleswig-Holstein (UKSH), Campus Kiel, Kiel, Germany.

Malignant melanoma is potentially life-threatening but in most cases curable if detected early. Willingness to pay (WTP) is a preference-based construct that reflects burden of disease by assessment of the monetary value for a hypothetical cure from disease. Since WTP (directly as total amount of money) has not been assessed so far in patients with low risk melanoma, it was interesting to gain insights in this patient population and then, in a second step, compare it directly with the WTP of their treating dermato-oncologists. Read More

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Rosacea-like cutaneous localization of small lymphocytic lymphoma unmasked by high-frequency-ultrasound.

Skin Res Technol 2018 May 23. Epub 2018 May 23.

Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, Unità Operativa di Dermatologia, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.

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Mesotherapy with Botulinum toxin for the treatment of refractory vascular and papulopustular rosacea.

J Am Acad Dermatol 2018 May 19. Epub 2018 May 19.

Senior Resident, Hindu Rao Hospital, New Delhi, India.

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Japanese Dermatological Association Guidelines: Guidelines for the treatment of acne vulgaris 2017.

J Dermatol 2018 May 21. Epub 2018 May 21.

Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan.

The Guidelines for the Treatment of Acne Vulgaris of the Japanese Dermatological Association was first published in Japanese in 2008 and revised in 2016 and 2017. These guidelines (GL) indicate the standard acne treatments in Japan and address pharmaceutical drugs and treatments applicable or in use in Japan. In these GL, the strength of the recommendation is based on clinical evidences as well as availability in Japanese medical institutions. Read More

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May 2018
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Assessment of rosacea symptom severity by genome-wide association study and expression analysis highlights immuno-inflammatory and skin pigmentation genes.

Hum Mol Genet 2018 May 16. Epub 2018 May 16.

Target Sciences, GlaxoSmithKline, King of Prussia, PA 19406, USA.

Rosacea is a common, chronic skin disease of variable severity with limited treatment options. The cause of rosacea is unknown, but it is believed to be due to a combination of hereditary and environmental factors. Little is known about the genetics of the disease. Read More

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May 2018
3 Reads

Mindfulness-Based Cognitive Hypnotherapy and Skin Disorders.

Am J Clin Hypn 2018 Jul;61(1):34-44

a University of South Florida , Tampa , FL, USA.

Mindfulness-based cognitive hypnotherapy integrates mindfulness, cognitive-behavioral therapy, and hypnotherapy to improve physical, emotional, mental, and/or spiritual aspects of skin disorders. Meditation, including mindfulness meditation, and hypnosis both utilize trance phenomena to help produce focalization and specific improvements in skin disorders through psycho-neuro-endocrine-immunologic mechanisms. Hypnosis, cognitive hypnotherapy, focused meditation, and mindfulness meditation are discussed with respect to improving various skin disorders including acne, acne excoriée, alopecia areata, atopic dermatitis, congenital ichthyosiform erythroderma, dyshidrotic dermatitis, erythema nodosum, erythromelalgia, furuncles, glossodynia, herpes simplex, hyperhidrosis, ichthyosis vulgaris, lichen planus, neurodermatitis, nummular dermatitis, postherpetic neuralgia, prurigo nodularis, pruritus, psoriasis, rosacea, trichotillomania, urticaria, verruca vulgaris, and vitiligo. Read More

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A case report of granulomatous rosacea of the face.

Singapore Med J 2018 04;59(4):228-229

National Skin Centre, Singapore.

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April 2018
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Dual-Frequency Ultrasound as a New Treatment Modality for Refractory Rosacea: A Retrospective Study.

Dermatol Surg 2018 May 9. Epub 2018 May 9.

Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, Korea.

Background: Dual-frequency ultrasound (DFU) has emerged as a new treatment modality for improving inflammatory skin disorders. Although there have been few pilot studies, there are a limited number of studies that investigated efficacy of DFU on refractory rosacea.

Objective: This study investigated the effect of DFU on patients with refractory rosacea. Read More

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Which acne treatment has the best influence on health-related quality of life? Literature review by the European Academy of Dermatology and Venereology Task Force on Quality of Life and Patient Oriented Outcomes.

J Eur Acad Dermatol Venereol 2018 May 5. Epub 2018 May 5.

Department of Dermatology, Venereology and Allergology, Wrocław Medical University, Wrocław, Poland.

According to results of a recent literature search performed by the European Academy of Dermatology and Venereology (EADV) Task Forces (TF) on Quality of Life and Patient Oriented Outcomes (QoL and PO) and Acne, Rosacea and Hidradenitis Suppurativa (ARHS), most of the publications where health-related (HR) QoL of acne patients was studied were clinical trials. Members of the EADV TF on QoL and PO decided to detect which acne treatment has the best influence on HRQoL of acne patients. A new literature search was organized to find publications on acne treatment where the HRQoL of patients was assessed as an outcome measure. Read More

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May 2018
2 Reads

Skin mites in mice (Mus musculus): high prevalence of Myobia sp. (Acari, Arachnida) in Robertsonian mice.

Parasitol Res 2018 Jul 4;117(7):2139-2148. Epub 2018 May 4.

Departament de Biologia Animal, Biologia Vegetal i Ecologia, Facultat de Biociències, Universitat Autònoma de Barcelona, Bellaterra, 08193, Barcelona, Spain.

Myobia sp. and Demodex sp. are two skin mites that infest mice, particularly immunodeficient or transgenic lab mice. Read More

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[Time to limit the use of antibiotics in rosacea!]

Lakartidningen 2018 Apr 24;115. Epub 2018 Apr 24.

Linkopings universitet - Linkoping, Sweden Linkopings universitet - Linkoping, Sweden.

Rosacea is a chronic inflammatory disease with facial erythema and papulopustules. It is common in middle-aged/elderly persons and often affects self-perception and social well-being. It is generally classified into four subtypes. Read More

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Skin neurogenic inflammation.

Semin Immunopathol 2018 May 30;40(3):249-259. Epub 2018 Apr 30.

Department of Dermatology, University of California San Diego, 9500 Gilman Drive #0869, La Jolla, CA, 92093, USA.

The epidermis closely interacts with nerve endings, and both epidermis and nerves produce substances for mutual sustenance. Neuropeptides, like substance P (SP) and calcitonin gene-related protein (CGRP), are produced by sensory nerves in the dermis; they induce mast cells to release vasoactive amines that facilitate infiltration of neutrophils and T cells. Some receptors are more important than others in the generation of itch. Read More

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May 2018
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Oral Azithromycin: A Treatment Option for Papulopustular Rosacea.

Authors:
M Blanes

Actas Dermosifiliogr 2018 Apr 25. Epub 2018 Apr 25.

Servicio de Dermatología, Hospital General Universitario de Alicante, Alicante, España. Electronic address:

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Papulopustular Rosacea: Response to Treatment with Oral Azithromycin.

Actas Dermosifiliogr 2018 Apr 23. Epub 2018 Apr 23.

Servicio de Dermatología, Hospital Virgen de la Arrixaca, El Palmar, Murcia, España.

Introduction: Oral tetracyclines and topical antibiotics have been used to treat papulopustular rosacea (PPR) for years, but it is not uncommon to find patients who do not respond to this standard treatment. In such refractory cases, oral azithromycin has proven to be an effective option.

Material And Method: We conducted a prospective pilot study of 16 patients with PPR who were treated with oral azithromycin after a lack of response to oral doxycycline and metronidazole gel. Read More

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The therapeutic effect of artesunate on rosacea through the inhibition of the JAK/STAT signaling pathway.

Mol Med Rep 2018 Jun 16;17(6):8385-8390. Epub 2018 Apr 16.

Department of Dermatology, Nanxiang Hospital of Jiading, Shanghai 201802, P.R. China.

Acne rosacea is a type of chronic dermatosis with the characteristics of erubescence, angiotelectasis and pustule formation. However, current treatment methods are limited due to the side effects. Artesunate demonstrated a promising therapeutic efficacy with a high safety margin. Read More

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June 2018
3 Reads

Dose, duration, and cost: opportunities to improve use of long-term oral antibiotics for people with rosacea.

J Dermatolog Treat 2018 May 7:1-5. Epub 2018 May 7.

d Department of Dermatology , Penn State Milton S. Hershey Medical Center , Hershey , PA , USA.

Background: Systemic antibiotics are often used to treat rosacea and tetracyclines are the most common antibiotic prescribed; however, there is ambiguity among clinical guideline suggestions. Importantly, there is an increasing call to all clinicians to curtail antibiotic use.

Objective: To investigate the utilization and cost of long-term oral antibiotic use for the treatment of rosacea, including ocular rosacea. Read More

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May 2018
2 Reads

It takes one to know one: exploring patient dialogue on rosacea web-based platforms and their potential for significant harm.

Authors:
Laura H Riddoch

J Dermatolog Treat 2018 May 10:1-11. Epub 2018 May 10.

a School of Medicine , University of Dundee , Dundee , Scotland.

Background: Rosacea is a non-curable skin condition, leading patients to turn self-management options from web-based platforms. Self-management can be dangerous possibly under-reported.

Aim: To discover the extent of online material and determine the potential for harm influenced by rosacea internet sources. Read More

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May 2018
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Can the tea tree oil (Australian native plant: Melaleuca alternifolia Cheel) be an alternative treatment for human demodicosis on skin?

Parasitology 2018 Apr 18:1-11. Epub 2018 Apr 18.

Department of Pathology,Monash Medical Centre and Department of Medicine,Monash University,Clayton,Victoria,Australia.

Australian tea tree oil (TTO) and its extract terpinen-4-ol (T4O) are found to be effective in moderating demodex-related diseases. Their possible effects are lowering the mite counts, relieving the demodex-related symptoms and modulating the immune system especially the inflammatory response. This review summarizes the topical treatments of TTO and T4O in human demodicosis, their possible mechanism of actions, side-effects and potential resistance in treating this condition. Read More

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April 2018
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Flushing Disorders Associated with Gastrointestinal Symptoms: Part 2, Systemic Miscellaneous Conditions.

Clin Med Res 2018 Apr 12. Epub 2018 Apr 12.

University of Central Florida College of Medicine/HCA Consortium Graduate Medical Education, North Florida Regional Medical Center, 6500 W Newberry Rd, Gainesville, FL 32605

Flushing disorders with involvement of the gastrointestinal tract represent a heterogeneous group of conditions. In part 1 discussed were neuroendocrine tumors (NET), mast cell activation disorders (MCAD), and hyperbasophilia. In this section are covered the remaining flushing disorders which primarily or secondarily involves the gastrointestinal tract. Read More

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April 2018
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Flushing Disorders Associated with Gastrointestinal Symptoms: Part 1, Neuroendocrine Tumors, Mast Cell Disorders and Hyperbasophila.

Clin Med Res 2018 Apr 12. Epub 2018 Apr 12.

University of Central Florida College of Medicine/HCA Consortium Graduate Medical Education, North Florida Regional Medical Center, 6500 W Newberry Rd, Gainesville, FL 32605

Flushing is the subjective sensation of warmth accompanied by visible cutaneous erythema occurring throughout the body with a predilection for the face, neck, pinnae, and upper trunk where the skin is thinnest and cutaneous vessels are superficially located and in greatest numbers. Flushing can be present in either a wet or dry form depending upon whether neural-mediated mechanisms are involved. Activation of the sympathetic nervous system results in wet flushing, accompanied by diaphoresis, due to concomitant stimulation of eccrine sweat glands. Read More

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Analysis of the effect of temperature on protein abundance in Demodex-associated Bacillus oleronius.

Pathog Dis 2018 06;76(4)

Department of Biology, Maynooth University, Co. Kildare, Ireland.

A potential role for bacteria in the induction of rosacea has been suggested. The aim of this work was to characterise the effect of temperature on the production of immunostimulatory proteins by Bacillus oleronius-a bacterium to which rosacea patients show sera reactivity and which was originally isolated from a Demodex mite from a rosacea patient. The affected skin of rosacea patients is at a higher temperature than unaffected skin, and it was postulated that this might alter the protein expression pattern of B. Read More

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Reduction in ultraviolet B light-induced erythema by oxymetazoline and brimonidine is mediated by different α-adrenoceptors.

Exp Dermatol 2018 Apr 10. Epub 2018 Apr 10.

Research, Allergan plc, Irvine, CA, USA.

When applied topically, oxymetazoline and brimonidine reduce the persistent facial erythema of rosacea; this effect is mediated by cutaneous vasoconstriction induced by postsynaptic activation of α-adrenoceptors. We investigated the α-adrenergic pharmacology of oxymetazoline and brimonidine. Functional activity on α-adrenoceptors was evaluated in vitro in HEK293 cells stably expressing single receptor subtypes using a fluorometric imaging plate reader Ca influx assay. Read More

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April 2018
1 Read

[Rhinophyma : Successful treatment with low-dose oral isotretinoin].

Hautarzt 2018 Apr 10. Epub 2018 Apr 10.

Karlsruhe MVZ Dres. Raulin und Kollegen, Kaiserstr. 104, 76133, Karlsruhe, Deutschland.

Rhinophyma is a form of rosacea and is often cosmetically disfiguring. There are various therapeutic ablation modalities. Surgery is often associated with down-time and side-effects. Read More

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Pulsed dye laser treatment of rosacea using a novel 15 mm diameter treatment beam.

Lasers Surg Med 2018 Apr 10. Epub 2018 Apr 10.

Syneron-Candela Corporation, Wayland, Massachusetts.

Background: The pulsed-dye laser has been used to treat facial redness and rosacea for decades. Recent advances in dye laser technology enable 50% higher output energies supporting 50% larger treatment areas, and beam-diameters up to 15 mm with clinically-relevant fluences. In this study, we investigate this novel pulsed-dye laser using a 15 mm diameter beam for treatment of rosacea. Read More

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April 2018
2 Reads

Chronic blepharitis like picture in patients with Discoid lupus erythematosis - Case series.

Nepal J Ophthalmol 2017 Jul;9(18):175-179

Background: Blepharitis is a very common condition encountered in ophthalmology outpatient care department. Dermatological diseases like seborrheic keratopathy and rosacea have been frequently discussed as being associated with blepharitis. However Discoid lupus erythematosis [DLE], an autoimmune condition has only rarely been reported to involve the eyelids mimicking blepharitis. Read More

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Idiopathic facial aseptic granuloma-A diagnostic challenge in pediatric dermatology.

Pediatr Dermatol 2018 Apr 6. Epub 2018 Apr 6.

Department of Dermatology, Rady Children's Hospital, San Diego, CA, USA.

Idiopathic facial aseptic granuloma is a distinct, benign lesion that presents in very young children and is characterized by a painless facial nodule that usually appears on the cheek. It is typically characterized by a prolonged course but heals spontaneously or in response to antibiotic treatment. The challenge is to diagnose this entity correctly, ideally based on clinical acumen, to avoid surgical intervention with facial sutures and the resultant scarring and unnecessary treatment interventions. Read More

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April 2018
1 Read

A report and follow up of a patient with disseminated superficial actinic porokeratosis (DSAP) undergoing novel systemic treatment with palifermin (a keratinocyte growth factor) during chemotherapy.

Dermatol Online J 2018 Feb 15;24(2). Epub 2018 Feb 15.

Department of Medicine, St Vincent's Hospital, Melbourne, Victoria, Australia,.

Disseminated superficial actinic porokeratosis (DSAP) is an inherited dermatosis triggered by chronic ultraviolet light exposure. Cosmetic improvement has been noted with topical therapies or laser treatment. Lesions of DSAP are precancerous, having been reported to develop into squamous cell carcinomas (SCCs) or basal cell carcinomas (BCCs) occasionally. Read More

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February 2018
2 Reads

Allergic contact dermatitis from formaldehyde mimicking impetigo and initiating rosacea.

Contact Dermatitis 2018 May;78(5):359-361

Lund University, Skane University Hospital, Department of Occupational and Environmental Dermatology, Malmö, 205 02, Sweden.

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May 2018
2 Reads

A Study on Vitamin D and Cathelicidin Status in Patients with Rosacea: Serum Level and Tissue Expression.

Ann Dermatol 2018 Apr 21;30(2):136-142. Epub 2018 Feb 21.

Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, Korea.

Background: Rosacea is a chronic inflammatory disease characterized by centrofacial erythema. Excess cathelicidin is suggested to be important to the pathophysiology of the disease. Recently, presence of a vitamin D response element was revealed in the cathelicidin gene promoter. Read More

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April 2018
3 Reads

Dermocosmetics for Use in Rosacea: Guideline of the Society for Dermopharmacy.

Skin Pharmacol Physiol 2018 29;31(3):147-154. Epub 2018 Mar 29.

Department of Dermatology and Allergology, Ludwig-Maximilians University, Munich, Germany.

Rosacea is a widespread inflammatory skin disease that is chronically recurrent and affects predominately the central parts of the face. Affected individuals typically react to numerous cosmetics with redness, burning, and/or worsening of the complexion. Consequently, there is a high demand for dermocosmetics that do not provoke such reactions and are suitable for use in rosacea. Read More

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March 2018
1 Read

The impact of age, sex, blepharitis, rosacea and rheumatoid arthritis on mite infection.

Arch Med Sci 2018 Mar 17;14(2):353-356. Epub 2016 Jun 17.

Department of Histology and Embryology, Biostructure Center, Medical University of Warsaw, Warsaw, Poland.

Introduction: Two human-specific species have been described: and . A medical condition caused by the presence of is called demodicosis.

Material And Methods: The study material comprised eyelashes collected from 1499 patients. Read More

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March 2018
2 Reads