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    1 OF 67

    Demodicidosis Involving Human Face.
    Indian J Dermatol Venereol Leprol 1979 May-Jun;45(3):203-205
    From the face of each of 9 patients having rosacea-like lesions the follicle mites identified as Demodex folliculorum (DF) (Simon) were in varying numbers. In our control cases no mites were demonstrated from similar sites. Treatment with one percent lindane (Cosmascab lotion-Napha) applied locally for seven consecutive days improved the condition in all patients. Read More

    Rosacea Fulminans Precipitated by Acute Stress: A Case Report Describing an Integrative Approach for a Patient Reluctant to Use Isotretinoin.
    Integr Med (Encinitas) 2016 Dec;15(6):32-35
    , is a medical student at Indiana University; , is assistant professor of clinical dermatology at Indiana University; is a resident at Geisinger Health.
    Context: Rosacea fulminans is a rare skin disorder with a multifactorial etiology. Stress is one of the common precipitating factors of this condition but is not often targeted in treatment. Isotretinoin is considered part of the first-line therapy for this condition but, in cases where its use is restricted, other therapeutic interventions as part of an integrative approach may be effective. Read More

    Friends or Foes? Host defense (antimicrobial) peptides and proteins in human skin diseases.
    Exp Dermatol 2017 Feb 13. Epub 2017 Feb 13.
    Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
    Host defense peptides/proteins (HDPs), also known as antimicrobial peptides/proteins (AMPs), are key molecules in the cutaneous innate immune system. AMPs/HDPs historically exhibit broad-spectrum killing activity against bacteria, enveloped viruses, fungi and several parasites. Recently, AMPs/HDPs were shown to have important biological functions, including inducing cell proliferation, migration and differentiation; regulating inflammatory responses; controlling the production of various cytokines/chemokines; promoting wound healing; and improving skin barrier function. Read More

    Ten-year incidence and prevalence of clinically diagnosed blepharitis in South Korea: A nationwide population-based cohort study.
    Clin Exp Ophthalmol 2017 Feb 9. Epub 2017 Feb 9.
    Department of Ophthalmology, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.
    Importance: Blepharitis is one of the most common conditions. However, no study has yet evaluated the epidemiology by evaluating a large population-based sample.

    Background: To evaluate the incidence and prevalence of clinically diagnosed blepharitis in South Korea. Read More

    Development and Clinical Validation of a Novel Photography-based Skin Erythema Evaluation System: A Comparison with the Calculated Consensus of Dermatologists.
    Int J Cosmet Sci 2017 Feb 8. Epub 2017 Feb 8.
    Department of Biomedical Engineering, Seoul National University College of Medicine, Seoul, 110-799, Korea.
    Erythema is the most common presenting sign of skin conditions [1,2]. Erythema reflects the degree of inflammation associated with various diseases, such as atopic dermatitis, psoriasis, and lupus erythematosus; it is also cosmetically troublesome in subjects with flushing, rosacea, and photoaging [3,4]. In addition, there are vascular disorders that present with erythema, such as nevus flammeus, telangiectasia, and post-acne erythema [5]. Read More

    Activation of p38 and Erk Mitogen-Activated Protein Kinases Signaling in Ocular Rosacea.
    Invest Ophthalmol Vis Sci 2017 Feb;58(2):843-848
    Department of Ophthalmology, Albany Medical College, Albany, New York, United States 5Department of Molecular and Cellular Physiology, Albany Medical College, Albany, New York, United States.
    Purpose: Rosacea-related cutaneous inflammation is a common cause of ocular surface disease. Currently, there are no specific pharmacologic therapies to treat ocular rosacea. Here, we aimed at determining the differences in intracellular signaling activity in eyelid skin from patients with and without ocular rosacea. Read More

    A Report of Two Cases of Solid Facial Edema in Acne.
    Dermatol Ther (Heidelb) 2017 Feb 6. Epub 2017 Feb 6.
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
    Introduction: Solid facial edema (SFE) is a rare complication of acne vulgaris. To examine the clinical features of acne patients with solid facial edema, and to give an overview on the outcome of previous topical and systemic treatments in the cases so far published.

    Methods: We report two cases from Switzerland, both young men with initially papulopustular acne resistant to topical retinoids. Read More

    Erythroid Differentiation Regulator 1 as a Novel Biomarker for Hair Loss Disorders.
    Int J Mol Sci 2017 Feb 3;18(2). Epub 2017 Feb 3.
    Department of Dermatology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 07345, Korea.
    Erythroid differentiation regulator 1 (Erdr1) is known to be involved in the inflammatory process via regulating the immune system in many cutaneous disorders, such as psoriasis and rosacea. However, the role of Erdr1 in various hair loss disorders remains unclear. The aim of this study was to investigate the putative role of Erdr1 in alopecias. Read More

    De novo characterization of microRNAs in oriental fruit moth Grapholita molesta and selection of reference genes for normalization of microRNA expression.
    PLoS One 2017 3;12(2):e0171120. Epub 2017 Feb 3.
    Department of Entomology, China Agricultural University, Beijing, China.
    MicroRNAs (miRNAs) are a group of endogenous non-coding small RNAs that have critical regulatory functions in almost all known biological processes at the post-transcriptional level in a variety of organisms. The oriental fruit moth Grapholita molesta is one of the most serious pests in orchards worldwide and threatens the production of Rosacea fruits. In this study, a de novo small RNA library constructed from mixed stages of G. Read More

    Four cases of Morbihan disease successfully treated with doxycycline.
    J Dermatol 2017 Feb 2. Epub 2017 Feb 2.
    Department of Dermatology, Kitakami Saiseikai Hospital, Kitakami, Japan.
    Morbihan disease (MD) is rosacea-like disease characterized by persistent lymphedema on the upper half of the face. Currently, there is no established standard treatment for MD. Recently, MD has been reported to be associated with the infiltration of mast cells. Read More

    9th Skin Academy Symposium: Building Bridges in Dermatology Chair's Introduction.
    Dermatol Ther (Heidelb) 2017 Jan 1;7(Suppl 1):1-3. Epub 2017 Feb 1.
    Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
    An introduction to the proceedings sharing an overview of presentations given as part of the 9th Skin Academy Symposium, held in Barcelona, Spain, April 9-10, 2016. The Skin Academy is an international and interdisciplinary dermatology initiative created to contribute to the growth in scientific knowledge of those dealing with skin diseases. This year's meeting aimed to 'build bridges' between the latest research and everyday clinical practice, providing dermatologists with important updates on some of the most common skin diseases, as well as current 'hot' topics. Read More

    Acne and Rosacea.
    Dermatol Ther (Heidelb) 2017 Jan 1;7(Suppl 1):43-52. Epub 2017 Feb 1.
    University of Western Ontario, Windsor, ON, Canada.
    Acne, one of the most common skin diseases, affects approximately 85% of the adolescent population, and occurs most prominently at skin sites with a high density of sebaceous glands such as the face, back, and chest. Although often considered a disease of teenagers, acne is occurring at an increasingly early age. Rosacea is a chronic facial inflammatory dermatosis characterized by flushing (or transient facial erythema), persistent central facial erythema, inflammatory papules/pustules, and telangiectasia. Read More

    A case report of combination treatment with potassium-titanyl phosphate laser and brimonidine topical gel in erythematotelangiectatic rosacea.
    J Cosmet Laser Ther 2017 Jan 31. Epub 2017 Jan 31.
    a Department of Dermatology , Venerology and Allergology, Charité Universitätsmedizin Berlin , Charitéplatz 1, 10117 Berlin , Germany.
    Laser therapies have been shown to provide symptom improvement in patients with erythema and telangiectasia of rosacea; however, they are associated with side effects such as erythema. Combinatorial treatment with pharmacological agents and laser have demonstrated better efficacy, fewer side effects and continued long-term remission compared with monotherapies. A case of moderate facial erythema that responded well to combination treatment with brimonidine 3 mg/g gel and a treatment course of potassium-titanyl phosphate (KTP) laser therapy is presented, showing a reduction from baseline, maintained after final laser session, by applying brimonidine 3 mg/g gel daily. Read More

    Emerging strategies for the diagnosis and treatment of meibomian gland dysfunction: Proceedings of the OCEAN group meeting.
    Ocul Surf 2017 Jan 26. Epub 2017 Jan 26.
    Department of Ophthalmology, Ludwig Maximilian University, Munich, Germany.
    Meibomian gland dysfunction (MGD) is a common and chronic disorder that has a significant adverse impact on patients' quality of life. It is a leading cause of evaporative dry eye disease (DED), as meibomian glands play an important role in providing lipids to the tear film, which helps to retard the evaporation of tears from the ocular surface. MGD is also often present in conjunction with primary aqueous-deficient DED. Read More

    Sebaceous gland rich skin is characterized by TSLP expression and distinct immune surveillance which is disturbed in rosacea.
    J Invest Dermatol 2017 Jan 25. Epub 2017 Jan 25.
    Division of Dermatological Allergology; Department of Dermatology. Electronic address:
    The microbial community exhibits remarkable diversity on topographically distinct skin regions, which may be accompanied by differences in skin immune characteristics. Our aim was to compare the immune milieu of healthy sebaceous gland rich (SGR) and sebaceous gland poor (SGP) skin areas, and to analyze its changes in an inflammatory disease of SGR skin. For this purpose, immunohistochemical, immunocytochemical and quantitative real-time PCR analyses of thymic stromal lymphopoietin (TSLP) and other cytokines, phenotypic immune cell markers and transcription factors were carried out in samples from SGP, SGR skin and from papulopustular rosacea (PPR). Read More

    Rosacea and risk of cancer in Denmark.
    Cancer Epidemiol 2017 Jan 26;47:76-80. Epub 2017 Jan 26.
    Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Denmark.
    Background: Rosacea is a common facial skin disorder with an estimated prevalence of 5-10% among Caucasians.

    Objective: We compared cancer incidence in patients previously diagnosed with rosacea with that in the general population.

    Methods: Nationwide cohort study of the Danish population using individual-level linkage of administrative registers. Read More

    Morbihan disease complicated by dermatosis neglecta: An unique presentation.
    J Cutan Pathol 2017 Jan 18. Epub 2017 Jan 18.
    Dermatopathology Division, Department of Pathology, Sylvester Comprehensive Cancer Center, Miami, Florida.
    Morbihan disease, also referred to as solid facial edema, or rosacea lymphedema, is a rare disorder that involves chronic erythema and solid edema of the cheeks, eyelids, forehead and glabella and may arise as a complication of acne vulgaris or rosacea. Of note, it may be the only initial presenting symptom of these associated diseases. Few cases have been described in the literature, as its first description by Robert Degos in 1957. Read More

    Successful Treatment of Rhinophyma With Fractionated Carbon Dioxide (CO2) Laser in an African-American Man: Case Report and Review of Literature of Fractionated CO2 Laser Treatment of Rhinophyma.
    J Drugs Dermatol 2016 Nov;15(11):1465-1468
    Rhinophyma, a late complication of rosacea (phymatous subtype), is a chronic, progressive dermatological condition. The classic pre- sentation of rhinophyma is nodular, thickened skin over the distal nose, and is often accompanied by underlying erythema secondary to in ammation. Due to the unpleasant aesthetic and dis guring appearance, rhinophyma may be associated with a signi cant nega- tive psychosocial impact, resulting in decreased patient quality-of-life. Read More

    Granulomatous & histiocytic dermatitides.
    Semin Diagn Pathol 2016 Dec 14. Epub 2016 Dec 14.
    Section of Dermatopathology, Division of Surgical & Cytological Pathology, University of Virginia Medical Center, Charlottesville, VA, USA. Electronic address:
    Granulomas of the skin may be classified in several ways. They are either infectious or non-infectious in character, and they contain areas of necrobiosis or necrosis, or not. Responsible infectious agents may be mycobacterial, fungal, treponemal, or parasitic organisms, and each case of granulomatous dermatitis should be assessed histochemically for those microbes. Read More

    Demodex spp. Infestation Associated with Treatment-Resistant Chalazia and Folliculitis.
    Turkiye Parazitol Derg 2016 Dec;40(4):208-210
    Yıldırım Beyazıt Üniversitesi Yenimahalle Eğitim ve Araştırma Hastanesi, Tıbbi Mikrobiyoloji Kliniği, Ankara, Türkiye.
    Demodecidosis is an ectoparasitosis of pilosebaceous unit caused by demodex mites. The disease may be a primary skin disease or a secondary disease to inflammatory dermatoses such as folliculitis and rosacea. Demodex spp. Read More

    Clinical characteristics and epidermal barrier function of papulopustular rosacea: A comparison study with acne vulgaris.
    Pak J Med Sci 2016 Nov-Dec;32(6):1344-1348
    Ji Li, Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008, China.
    Objective: To evaluate the clinical characteristics and epidermal barrier function of papulopustular rosacea by comparing with acne vulgaris.

    Methods: Four hundred and sixty-three papulopustular rosacea patients and four hundred and twelve acne vulgaris patients were selected for the study in Xiangya Hospital of Central South University from March 2015 to May 2016. They were analyzed for major facial lesions, self-conscious symptoms and epidermal barrier function. Read More

    Risk of inflammatory bowel disease in patients with rosacea: Results from a nationwide cohort study in Taiwan.
    J Am Acad Dermatol 2017 Jan 7. Epub 2017 Jan 7.
    Faculty of Medicine and Graduate Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan; Departments of Dermatology, Taichung Veterans General Hospital, Taichung, Taiwan. Electronic address:
    Background: A link between rosacea and inflammatory bowel disease (IBD) has been proposed with unknown mechanisms. Epidemiologic evidence of this association needs to be examined.

    Methods: In this nationwide cohort study, a total of 89,356 patients with rosacea and 178,712 matched patients without rosacea between 1997 and 2013 were identified in the Taiwanese National Health Insurance Research Database. Read More

    [Acne and rosacea in pregnancy].
    Hautarzt 2017 Feb;68(2):111-119
    Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland.
    Acne and rosacea are common chronic inflammatory skin diseases. During pregnancy these skin disorders may become aggravated, in rare cases occurring for the first time. There are no data available for rosacea and little data for acne concerning the course of these skin disorders during pregnancy. Read More

    Ocular acne rosacea in tertiary eye center in Saudi Arabia.
    Int Ophthalmol 2016 Dec 30. Epub 2016 Dec 30.
    Anterior Segment Division, King Khaled Eye Specialist Hospital, PO Box 7191, Riyadh, 11462, Kingdom of Saudi Arabia.
    Purpose: To report the most common presenting signs and symptoms of ocular rosacea for timely diagnosis and management.

    Methods: A retrospective chart review of 23 patients with a diagnosis of acne rosacea or a non-specific diagnosis was performed at a tertiary eye hospital. Patients with lid changes such as recurrent blepharitis; meibomianitis; recurrent chalazia; facial skin change such as papules, telangiectatic blood vessels, and/or rhinophyma were included. Read More

    DTB Select: 1 | January 2017.
    • Authors:
    Drug Ther Bull 2017 Jan 29;55(1):2-5. Epub 2016 Dec 29.
    Brimonidine gel: risk of exacerbation of rosacea ● Metformin for patients with moderately reduced kidney function ● Effect of an optimal cranberry dose on bacteriuria ● Amitriptyline and topiramate ineffective for paediatric migraine prophylaxis ● Etoricoxib: 60mg dose for RA and ankylosing spondylitis ● CRP and diagnosis of CAP ● International travel and antimicrobial resistance ● Effect of telemedicine on diabetes control. Read More

    Clinical features of Korean patients with rhinophyma.
    J Dermatol 2016 Dec 27. Epub 2016 Dec 27.
    Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea.
    Rhinophyma results from hyperplasia of the sebaceous glands and connective tissue. Clinical features in Asian rhinophyma patients are largely underreported. In this study, we aimed to evaluate the clinical features of rhinophyma in Korean patients. Read More

    Rhinophyma: "Less is More" and "Old is Gold".
    Aesthetic Plast Surg 2017 Feb 23;41(1):232-233. Epub 2016 Dec 23.
    Plastic Surgery Unit, Department of Surgery "P Valdoni", Sapienza University, Viale del Policlinico 155, 00161, Rome, Italy.
    Rhinophyma is a deforming disorder of the nose and considered the most severe stage of rosacea. Since 1950, a large variety of surgical and non-surgical treatments have been adopted to treat it. From January 2014 to June 2016, we treated ten patients (average age: 58 years) affected by moderate (4) and severe (6) degrees of rhinophyma. Read More

    Quality of life in adults with facial port-wine stains.
    J Am Acad Dermatol 2016 Dec 9. Epub 2016 Dec 9.
    University of California Irvine, Department of Dermatology, Irvine, California.
    Background: Facial port-wine stains (PWS) are considered by some an aesthetic skin problem, yet impact on quality of life (QoL) has not been objectively documented.

    Objective: We sought to (1) characterize the effect of PWS on QoL in adults, (2) to identify the clinical and demographic factors that affect QoL, and (3) to compare our results with QoL studies in other skin conditions.

    Methods: In total, 244 adults with facial PWS completed an online QoL survey, which included the Skindex-29 instrument. Read More

    Immune-related alopecia (areata and universalis-type) in cancer patients receiving immune checkpoint inhibitors.
    Br J Dermatol 2016 Dec 11. Epub 2016 Dec 11.
    Dermatology Service, Institut Universitaire du Cancer.
    CTLA-4, PD-1, and PD-L1 monoclonal antibodies, commonly known as immune checkpoint inhibitors, are used for the treatment of various malignancies. The mechanism of action involves the inhibition of negative regulators of immune activation, which results in many patients developing immune-related adverse events (irAEs) including endocrinopathies, pneumonitis, colitis, hepatitis and dermatologic events. Dermatologic irAEs include maculopapular rash, pruritus, vitiligo, blistering disorders, mucocutaneous lichenoid eruptions, rosacea, and exacerbation of psoriasis. Read More

    Rosacea: a Clinical Review.
    Dermatol Reports 2016 Jun 23;8(1):6387. Epub 2016 Jun 23.
    Private Practitioner, Hudpoliklinikken , Namsos, Norway.
    Rosacea is a field within dermatology with new insight within immunological research and new treatment-algorithm. Patient education on rosacea and appropriate treatments is an important aspect in helping patients succeed with therapy. Treatment should be tailored to each individual patient, taking into account: symptoms, trigger factors, patients' wishes, most bothersome symptoms, psychological aspect, individual needs. Read More

    Roles of Erythroid Differentiation Regulator 1 (Erdr1) on Inflammatory Skin Diseases.
    Int J Mol Sci 2016 Dec 8;17(12). Epub 2016 Dec 8.
    Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.
    Erythroid Differentiation Regulator 1 (Erdr1) is known as a hemoglobin synthesis factor which also regulates cell survival under conditions of stress. In addition, previous studies have revealed the effects of Erdr1 on cancer progression and its negative correlation with interleukin (IL)-18, a pro-inflammatory cytokine. Based on this evidence, the therapeutic effects of Erdr1 have been demonstrated in several inflammatory skin diseases such as malignant skin cancer, psoriasis, and rosacea. Read More

    The Effect of Recurrent Pulsed Dye Laser Treatments in Rosacea Patients.
    J Cosmet Laser Ther 2016 Dec 6:1-17. Epub 2016 Dec 6.
    b Plastic Surgery Center of Pennsylvania , Erie , United States.
    Background: Rosacea is common chronic skin condition and is known to have a negative impact on patient's quality of life. The use of pulsed dye laser treatment to improve quality of life is well documented in the literature. Prior work has emphasized a single series of laser treatments but we investigated the effect of recurrent pulsed dye laser treatment on patient's symptomalology and quality of life. Read More

    Idiopathic Facial Aseptic Granuloma in a 13-Year-Old Boy Dramatically Improved with Oral Doxycycline and Topical Metronidazole: Evidence for a Link with Childhood Rosacea.
    Case Rep Dermatol 2016 May-Aug;8(2):197-201. Epub 2016 Jul 19.
    Department of Dermatology, Centre Hospitalier de Saint-Brieuc, Saint-Brieuc, France.
    Idiopathic facial aseptic granuloma (IFAG) is a rare, benign pediatric dermatological lesion that occurs in children between 8 months and 13 years of age. The pathogenesis of IFAG is still unclear but it is likely to be associated with granulomatous rosacea in childhood. Here we describe a case of IFAG in a 13-year-old boy who showed a dramatic response to oral doxycycline and topical metronidazole, which supports the hypothesis that IFAG may belong to the spectrum of rosacea. Read More

    Comparative Efficacy of Radiofrequency and Pulsed Dye Laser in the Treatment of Rosacea.
    Dermatol Surg 2017 Feb;43(2):204-209
    *All authors are affiliated with the Department of Dermatology, School of Medicine, Chungnam National University, Daejeon, Korea.
    Background: Laser and light-based therapies have been used successfully in the treatment of rosacea; however, evidence is lacking regarding the efficacy of radiofrequency (RF).

    Objective: This study evaluated the efficacy of RF in the treatment of rosacea compared with pulsed dye laser (PDL).

    Methods: Thirty patients with rosacea (erythematotelangiectatic rosacea [ETR], n = 20; papulopustular rosacea [PPR], n = 10) were enrolled in a randomized, controlled, split-face study. Read More

    The Critical and Multifunctional Roles of Antimicrobial Peptides in Dermatology.
    Dermatol Clin 2017 Jan;35(1):39-50
    Department of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address:
    Antimicrobial peptides are central effector molecules in skin immunology. The functions of antimicrobial peptides in skin diseases include the ability to act as cytokines or growth factors, driving disorders such as psoriasis and rosacea, as well as their action as natural antibiotics to control bacteria that influence diseases such as atopic dermatitis and acne. Read More

    [Minocycline-induced hyperpigmentation: not uncommon, but nonetheless important to recognise].
    Ned Tijdschr Geneeskd 2016 ;160(0):D483
    Radboudumc, Nijmegen.
    Background: Minocycline, a broad-spectrum antibiotic from the group of tetracyclins, is frequently prescribed for acne vulgaris and rosacea. Hyperpigmentation is a relatively common side effect of this drug and can lead to multiple unsightly skin lesions, which are not always reversible. It can take a long period, from a few months to several years, before the lesions have completely vanished. Read More

    Patient-reported outcomes of azelaic acid foam 15% for patients with papulopustular rosacea: secondary efficacy results from a randomized, controlled, double-blind, phase 3 trial.
    Cutis 2016 Oct;98(4):269-275
    Bayer Pharmaceuticals, Berlin, Germany.
    Patient-reported treatment outcomes are important for evaluating the impact of drug therapies on patient experience. A randomized, double-blind, vehicle-controlled, parallel-group, multicenter, phase 3 study was conducted in 961 participants to assess patient perception of efficacy, utility, and effect on quality of life (QOL) of an azelaic acid (AzA) 15% foam formulation for the treatment of papulopustular rosacea (PPR). Secondary end points included patient-reported global assessment of treatment response, global assessment of tolerability, and opinion on cosmetic acceptability and practicability of product use. Read More

    Rosacea Management: Update on general measures and topical treatment options.
    J Dtsch Dermatol Ges 2016 Dec;14 Suppl 6:17-27
    Department of Dermatology and, UCD Charles Institute for Translational Dermatology, University College Dublin, Dublin, Ireland.
    Although there is presently no cure for rosacea, there are several recommended treatment options available to control many of the symptoms and to prevent them from getting worse. In addition to self-help measures like avoidance of trigger factors and proper skin care, rosacea management should include topical medications as one of the first-line choices for patients with erythematous and mild to severe papulopustular rosacea. Since mixed forms of characteristic rosacea symptoms are more common, medical treatment must be symptom-tailored for each individual case and will often involve a combination therapy. Read More

    Pathogenese und Klinik der Rosazea als Schlüssel für eine symptomorientierte Therapie.
    J Dtsch Dermatol Ges 2016 Dec;14 Suppl 6:4-16
    Klinik für Hautkrankheiten, Allgemeine Dermatologie und Venerologie, Universitätsklinikum Münster.
    Rosazea ist eine häufige chronisch-entzündliche Hauterkrankung, die typischerweise bei Erwachsenen vorkommt und das Gesicht betrifft. Synonyme der Rosazea sind Acne rosacea, Kupferfinne, Rotfinne, Couperose und Rosacea. Die Erkrankung ist durch einen chronischen und schubartigen Verlauf gekennzeichnet und wird durch ein genetisch prädisponiertes, multifaktorielles Geschehen bedingt. Read More

    Physical modalities for the treatment of rosacea.
    J Dtsch Dermatol Ges 2016 Dec;14 Suppl 6:38-43
    Helios Hospital Centre Wuppertal, Department of Dermatology, Allergology and Dermatosurgery, Wuppertal, Germany.
    Rosacea is characterised by a wide variety of vascular changes. Apart from telangiectasia and erythema, often so-called flushing occurs. These vascular abnormalities can be targeted with specific light and laser devices. Read More

    State of the art: systemic rosacea management.
    J Dtsch Dermatol Ges 2016 Dec;14 Suppl 6:29-37
    Department of Dermatology and UCD Charles Institute for Translational Dermatology,  University College Dublin, Dublin, Ireland.
    Based on numerous trials, oral tetracyclines and most commonly their second-generation derivative doxycycline have become the main pillar in systemic rosacea treatment. However, the only preparation that has been approved so far in this setting is 40 mg doxycycline in an anti-inflammatory dosage and with a modified release formulation. With the introduction of this once-daily, non-antibiotic dosing of doxycycline, oral therapy is more commonly prescribed as first-line treatment in moderate to severe papulopustular rosacea. Read More

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