3,730 results match your criteria Rosacea


Nested Polymerase Chain Reaction and Cutaneous Tuberculosis.

Am J Dermatopathol 2018 Nov 27. Epub 2018 Nov 27.

Unidad de Investigación Médica en Inmunoquímica, Hospital de Especialidades, Centro Médico Nacional SXXI, IMSS, Mexico City, México.

The role of Mycobacterium tuberculosis in the etiology and pathogenesis of cutaneous tuberculosis is controversial because of the difficulties associated with demonstrating the presence of these mycobacteria in tuberculid cutaneous lesions by routinely available microbiological and histological techniques. In this study, we aimed to demonstrate the presence of M. tuberculosis in cutaneous tuberculosis. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001315DOI Listing
November 2018
1 Read

Dietary supplementation with turmeric polyherbal formulation decreases facial redness: a randomized double-blind controlled pilot study.

J Integr Med 2018 Nov 22. Epub 2018 Nov 22.

Department of Dermatology, University of California, Davis, Sacramento, CA 95816, USA; Department of Biological Sciences, California State University, Sacramento, CA 95819, USA; Pacific Skin Institute, Sacramento, CA 95815, USA. Electronic address:

Background: Facial redness is multifactorial in nature and may be a sign of many different conditions, including rosacea, photo damage and flushing. Herbal medicines have been used for thousands of years to treat a variety of dermatological conditions. Turmeric (Curcuma longa) and its constituents have been shown to mediate dilation and constriction of peripheral arterioles and have demonstrated anti-oxidant, anti-inflammatory and wound-healing properties. Read More

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http://dx.doi.org/10.1016/j.joim.2018.11.004DOI Listing
November 2018

Topical Oxymetazoline Cream 1.0% for Persistent Facial Erythema Associated With Rosacea: Pooled Analysis of the Two Phase 3, 29-Day, Randomized, Controlled REVEAL Trials

J Drugs Dermatol 2018 Nov;17(11):1201-1208

Background: Rosacea is a chronic dermatologic condition with limited treatment options. Methods: Data were pooled from two identically designed phase 3 trials. Patients with moderate to severe persistent erythema of rosacea were randomized to receive oxymetazoline cream 1. Read More

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November 2018
3 Reads

Use of an Alternative Method to Evaluate Erythema Severity in a Clinical Trial: Difference in Vehicle Response With Evaluation of Baseline and Postdose Photographs for Effect of Oxymetazoline Cream 1.0% for Persistent Erythema of Rosacea in a Phase 4 Study.

Br J Dermatol 2018 Nov 30. Epub 2018 Nov 30.

Allergan plc, Irvine, CA.

Background: Once-daily topical oxymetazoline cream 1.0% significantly reduced persistent facial erythema of rosacea in trials requiring live, static patient assessments.

Objective: To critically evaluate the methodology of clinical trials that require live, static patient assessments by determining whether assessment of erythema is different when reference to the baseline photograph is allowed. Read More

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http://dx.doi.org/10.1111/bjd.17462DOI Listing
November 2018
1 Read

Rosacea-specific quality of life questionnaire: translation, cultural adaptation and validation for Brazilian Portuguese.

An Bras Dermatol 2018 Nov/Dec;93(6):836-842

Department of Dermatology, Universidade Federal de São Paulo, São Paulo (SP), Brazil.

Background: Brazil does not have a rosacea-specific quality of life questionnaire.

Objectives: translation into Brazilian Portuguese, development of cultural adaptation, and validation of the RosaQoL disease-specific questionnaire for rosacea of any subtype.

Methods: the recommended procedures for translation, cultural adaptation, and validation of an instrument were followed, and three interviews were conducted: baseline; seven to fourteen days after baseline; and at four to six months. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20187192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256224PMC

Risk of psychiatric disorders in rosacea: A nationwide, population-based, cohort study in Taiwan.

J Dermatol 2018 Nov 22. Epub 2018 Nov 22.

Department of Dermatology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Rosacea has been reported to be associated with psychiatric disorders. Nevertheless, a nationwide study of the relationship between rosacea and comorbid psychiatric diseases in an Asian population has not been conducted. The aim of this study was to clarify the role of rosacea in the various psychiatric disorders by using a nationwide database in Taiwan. Read More

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http://dx.doi.org/10.1111/1346-8138.14705DOI Listing
November 2018
1 Read

Potassium Iodide for Cutaneous Inflammatory Disorders: A Monocentric, Retrospective Study.

Dermatology 2018 Nov 21:1-7. Epub 2018 Nov 21.

Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.

Objectives: Potassium iodide (KI) is a medication that has been used for decades in dermatology and it is mentioned as a treatment option in all major dermatology textbooks. Yet, there is little recent information on its efficacy. In our study, we wanted to retrospectively evaluate the therapy response to KI in our patients. Read More

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http://dx.doi.org/10.1159/000494614DOI Listing
November 2018
9 Reads

The Spectrum and Sequelae of Acne in Black South Africans Seen in Tertiary Institutions.

Skin Appendage Disord 2018 Oct 30;4(4):301-303. Epub 2018 May 30.

School of Public Health and Nursing, University of KwaZulu-Natal, Durban, South Africa.

Introduction: Acne is a chronic disorder of the pilosebaceous unit affecting all ethnic groups. It remains in the top 5 skin conditions seen worldwide. The paucity of data characterizing acne in South African Blacks led us to the documentation of types and sequelae of acne. Read More

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https://www.karger.com/Article/FullText/488689
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http://dx.doi.org/10.1159/000488689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219215PMC
October 2018
4 Reads

Body Piercing: A National Survey in France.

Dermatology 2019 7;235(1):71-78. Epub 2018 Nov 7.

FIMARAD, Hôpital Necker Enfants Malades, Paris, France.

Background: There are no recent data available in France regarding body piercing (BP).

Objective: We examined the demographics, motivations, quality of life, cutaneous conditions, and cutaneous side effects after BP within the French population.

Methods: A representative sample of 5,000 individuals (aged 15 and over) from the general population responded to a survey online between April and August 2017. Read More

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http://dx.doi.org/10.1159/000494350DOI Listing
November 2018
2 Reads

The relationship between inflammatory bowel disease and rosacea over the lifespan: A meta-analysis.

Clin Res Hepatol Gastroenterol 2018 Oct 30. Epub 2018 Oct 30.

School of Nursing, Qingdao University, Qingdao, Shandong, China. Electronic address:

Backgrounds And Aims: It has been argued that the relationship between inflammatory bowel disease (IBD) and rosacea is bi-directional, but this hypothesis has not been explicitly tested. This systematic review examines the bi-directional prospective relationships between IBD and rosacea.

Methods: A comprehensive search through PubMed and EMBASE was undertaken for studies investigating the association between two mainly forms of IBD [ulcerative colitis (UC) and Crohn's disease (CD)] and rosacea published in English until Jan 2018. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22107401183019
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http://dx.doi.org/10.1016/j.clinre.2018.09.009DOI Listing
October 2018
4 Reads

Association between rosacea severity and relative muscle mass: A cross-sectional study.

J Dermatol 2018 Oct 31. Epub 2018 Oct 31.

Department of Dermatology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Rosacea is thought to be associated with factors involved in metabolic syndrome (MetS). Muscle mass has a beneficial role in preventing MetS, but its link to rosacea remains unknown. We sought to investigate the association between rosacea severity and relative skeletal muscle mass. Read More

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http://doi.wiley.com/10.1111/1346-8138.14689
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http://dx.doi.org/10.1111/1346-8138.14689DOI Listing
October 2018
14 Reads

[FEATURES OF ROSACEA PATHOGENESIS IN PERIMENOPAUSAL WOMEN].

Georgian Med News 2018 Sep(282):99-102

Tbilisi State Medical University, Department of Dermatology and Venereology, Georgia.

In patients with rosacea, the monitoring of blood melatonin in the menopausal period, as one of the criteria for assessing the severity of the disease, seems appropriate and pathogenetically justified. The aim of this study was determination of blood melatonin, VEGF, IL-8 concentration in perimenopausal period of women suffering by rosacea. 43 to 65 years old 15 women with various clinical manifestations of rosacea, and severe climacteric syndrome were under observation. Read More

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September 2018
4 Reads

Association of Caffeine Intake and Caffeinated Coffee Consumption With Risk of Incident Rosacea in Women.

JAMA Dermatol 2018 Dec;154(12):1394-1400

Department of Dermatology, Warren Alpert Medical School, Brown University, Providence, Rhode Island.

Importance: Caffeine is known to decrease vasodilation and have immunosuppressant effects, which may potentially decrease the risk of rosacea. However, the heat from coffee may be a trigger for rosacea flares. The relationship between the risk of rosacea and caffeine intake, including coffee consumption, is poorly understood. Read More

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http://archderm.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamadermatol.2018.3301DOI Listing
December 2018
3 Reads

The role of phosphodiesterase 4 in the pathophysiology of atopic dermatitis and the perspective for its inhibition.

Exp Dermatol 2018 Oct 17. Epub 2018 Oct 17.

Pfizer Inc, Collegeville, Pennsylvania.

Atopic dermatitis (AD) is a highly prevalent, chronic inflammatory skin disease that affects children and adults. The pathophysiology of AD is complex and involves skin barrier and immune dysfunction. Many immune cytokine pathways are amplified in AD, including T helper (Th) 2, Th22, Th17 and Th1. Read More

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http://dx.doi.org/10.1111/exd.13808DOI Listing
October 2018
1 Read

Integrating the Integumentary System with the Arts: A Review of Dermatologic Findings in Artwork.

Authors:
Amit Om Anjali Om

J Clin Aesthet Dermatol 2018 Sep 1;11(9):21-27. Epub 2018 Sep 1.

Dr. Om is with the Division of Dermatology at Florida State University in Tallahassee, Florida.

The objectives of this review are to demonstrate that portraits, in their visual reflections of subjects faces and expressions, offer significant representations relevant to the field of dermatology and bring attention to an underappreciated aesthetic of dermatological conditions. The review comprises paintings that purposefully or inadvertently depict dermatological conditions. The findings were substantiated by searching PubMed using the keywords , , and , as well as combinations of these terms. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169602PMC
September 2018
8 Reads

An annotated catalogue of the pygmy grasshoppers of the tribe Scelimenini Bolívar, 1887 (Orthoptera: Tetrigidae) with two new Scelimena species from the Malay Peninsula and Sumatra.

Zootaxa 2018 Sep 25;4485(1):1-70. Epub 2018 Sep 25.

Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia.

Pygmy grasshoppers (Tetrigidae) are a speciose group of complicated taxonomy, with many species requiring clarification on their species boundaries, and more still awaiting discovery. Two new species of Scelimena Serville, 1838 are described: (1) from S. discalis species group S. Read More

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http://dx.doi.org/10.11646/zootaxa.4485.1.1DOI Listing
September 2018
1 Read

The toxic edge-A novel treatment for refractory erythema and flushing of rosacea.

Lasers Surg Med 2018 Oct 12. Epub 2018 Oct 12.

Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Purpose: Rosacea is a common, chronic facial skin disease that affects the quality of life. Treatment of facial erythema with intradermal botulinum toxin injection has previously been reported. The primary objective of the study was the safety and efficacy of thermal decomposition of the stratum corneum using a novel non-laser thermomechanical system (Tixel, Novoxel, Israel) to increase skin permeability for Botulinum toxin in the treatment of facial flushing of rosacea. Read More

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http://doi.wiley.com/10.1002/lsm.23023
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http://dx.doi.org/10.1002/lsm.23023DOI Listing
October 2018
10 Reads

Effects of combined oral doxycycline and topical cyclosporine treatment on ocular signs, symptoms, and tear film parameters in rosacea patients.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):466-470. Epub 2018 Oct 8.

Department of Ophthalmology, Adıyaman University, Turkey.

Purpose: This study reports the effects of combined use of oral doxycycline and topical cyclosporine on ocular signs, symptoms, and tear film parameters in rosacea patients.

Methods: Fifty-four right eyes of 54 patients were included in this study. All patients underwent full ophthalmologic examination-including best corrected visual acuity measurement, slit-lamp anterior segment and fundus examination, tear film break-up time, and Schirmer test-before treatment and six months post-treatment. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20180093
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http://dx.doi.org/10.5935/0004-2749.20180093DOI Listing
October 2018
3 Reads

Brimonidine displays anti-inflammatory properties in the skin through the modulation of the vascular barrier function.

Exp Dermatol 2018 Dec;27(12):1378-1387

GALDERMA R&D-Nestlé Skin Health, Sophia Antipolis, France.

Background: Rosacea is a chronic inflammatory skin disease. Characteristic vascular changes in rosacea skin include enlarged, dilated vessels of the upper dermis and blood flow increase. Brimonidine is approved for symptomatic relief of the erythema of rosacea. Read More

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http://dx.doi.org/10.1111/exd.13793DOI Listing
December 2018
13 Reads

Trends in utilization of topical medications for treatment of rosacea in the United States (2005-2014) - a cohort analysis.

J Am Acad Dermatol 2018 Oct 1. Epub 2018 Oct 1.

Department of Dermatology, Penn State Milton S. Hershey Medical Center, Hershey, PA.

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https://linkinghub.elsevier.com/retrieve/pii/S01909622183265
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http://dx.doi.org/10.1016/j.jaad.2018.09.039DOI Listing
October 2018
9 Reads

Comparative efficacy of short-pulsed intense pulsed light and pulsed dye laser to treat rosacea.

J Cosmet Laser Ther 2018 Oct 4:1-6. Epub 2018 Oct 4.

a Department of Dermatology , Korea University Ansan Hospital , Ansan , Korea.

Background: Laser and light-based therapies have often been used successfully to treat rosacea. Recently, short-pulsed intense pulsed light (IPL) that emitted pulse durations down to 0.5 ms was found to be effective for rosacea treatment. Read More

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https://www.tandfonline.com/doi/full/10.1080/14764172.2018.1
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http://dx.doi.org/10.1080/14764172.2018.1528371DOI Listing
October 2018
10 Reads

Toll-like receptor signaling induces the expression of lympho-epithelial Kazal-type inhibitor in epidermal keratinocytes.

J Dermatol Sci 2018 Nov 15;92(2):181-187. Epub 2018 Sep 15.

Department of Dermatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Science, Okayama, Japan.

Background: Lympho-epithelial Kazal-type inhibitor (LEKTI) tightly controls the activities of serine proteases such as kallikrein-related peptidase (KLK) 5 and KLK7 in the epidermis. LEKTI is known to be an essential molecule for the epidermal skin barrier, as demonstrated by SPINK5 nonsense mutation, which results in Netherton syndrome. Toll-like receptors (TLRs) recognize pathogen-associated molecular patterns or damage-associated molecular patterns and produce inflammatory cytokines, chemokines, and antimicrobial peptides. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09231811183032
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http://dx.doi.org/10.1016/j.jdermsci.2018.09.001DOI Listing
November 2018
2 Reads

Risk factors associated with frontal fibrosing alopecia: a multicentre case-control study.

Clin Exp Dermatol 2018 Sep 26. Epub 2018 Sep 26.

Dermatology Department, Hospital Universitario Ramon y Cajal, Madrid, Spain.

Background: Frontal fibrosing alopecia (FFA) is a chronic cicatricial alopecia with an increasing incidence and unknown aetiology.

Aim: To identify possible environmental and hormonal factors related to FFA.

Methods: We conducted a multicentre case-control study paired by sex and age, and recruited 664 women (335 cases and 329 controls) and 106 men (20 cases and 86 controls). Read More

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http://dx.doi.org/10.1111/ced.13785DOI Listing
September 2018
1 Read

Unilateral Facial Telangiectasia Macularis Eruptiva Perstansmimicking as Rosacea.

Indian Dermatol Online J 2018 Sep-Oct;9(5):351-353

Department of Dermatology, Armed Forces Medical College, Pune, Maharashtra, India.

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http://dx.doi.org/10.4103/idoj.IDOJ_313_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137648PMC
September 2018
6 Reads

First Report of Concomitant Tinea Faciei and Pityriasis Folliculorum: A Dermatomicrobiological Rarity.

Cureus 2018 Jul 20;10(7):e3017. Epub 2018 Jul 20.

Department of Microbiology, Prathima Institute of Medical Sciences, Karimnagar, IND.

Tinea faciei (TF) is a common dermatomicrobiological condition caused by dermatophytes involving the skin of the face but not the mustache and beard (Tinea barbae). It poses a diagnostic dilemma with its atypical clinical presentation. Pityriasis folliculorum (PF) is a dermatological condition that results in rosacea-like skin eruptions. Read More

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http://dx.doi.org/10.7759/cureus.3017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150771PMC
July 2018
1 Read

Morbihan Disease Treatment: Two Case Reports and a Systematic Literature Review.

Ophthalmic Plast Reconstr Surg 2018 Sep 24. Epub 2018 Sep 24.

Department of Ophthalmology, Weill Cornell Medical College, New York, New York, U.S.A.

Purpose: To assess the effectiveness of treatments for Morbihan disease.

Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a systematic review of the literature was performed on April 1, 2018, using PubMed, Google Scholar, and Excerpta Medica dataBASE with terms used to describe Morbihan disease, including "Morbihan Disease," "Morbihan Syndrome," "lymphedema rosacea," and "lymphedematous rosacea". Case reports or case series were included if they fulfilled the following criteria: published in English, peer-reviewed, and reported Morbihan disease. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001229DOI Listing
September 2018
1 Read

Role of serum 25-hydroxyvitamin D levels and vitamin D receptor gene polymorphisms in patients with rosacea: a case-control study.

Clin Exp Dermatol 2018 Sep 23. Epub 2018 Sep 23.

Department of Medical Biochemistry, Ufuk University Faculty of Medicine, Ankara, Turkey.

Background: Vitamin D has significant effects on the immune system and thereby on the pathogenesis of rosacea. However, there is a lack of information on the vitamin D status and vitamin D receptors (VDRs) of patients with rosacea.

Aim: To evaluate the role of vitamin D in rosacea susceptibility. Read More

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http://dx.doi.org/10.1111/ced.13769DOI Listing
September 2018

Global Epidemiology and Clinical Spectrum of Rosacea, Highlighting Skin of Color: Review and Clinical Practice Experience.

J Am Acad Dermatol 2018 Sep 18. Epub 2018 Sep 18.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Among individuals with skin of color, rosacea has been reported less frequently than in those with white skin, but it is not a rare disease. In fact, rosacea may be underreported and underdiagnosed in populations with skin of color because of the difficulty of discerning erythema and telangiectasia in dark skin, as well as underestimation of the susceptibility of more highly pigmented skin to dermatologic conditions like rosacea whose triggers include sun exposure. Many people with skin of color who have rosacea may experience delayed diagnosis leading to inappropriate or inadequate treatment, greater morbidity, and uncontrolled, progressive disease with disfiguring manifestations, including phymatous rosacea. Read More

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http://dx.doi.org/10.1016/j.jaad.2018.08.049DOI Listing
September 2018

Effects of dextran sulfate, 4-t-butylcyclohexanol, pongamia oil and hesperidin methyl chalcone on inflammatory and vascular responses implicated in rosacea.

Clin Cosmet Investig Dermatol 2018 7;11:421-429. Epub 2018 Sep 7.

Department of Pharmacology, Pierre FABRE Dermo-Cosmétique R&D Center, Toulouse, France,

Background: Rosacea is a chronic facial skin disorder characterized by inflammation and vascular abnormalities. The pathophysiology of rosacea involves increased activation of the capsaicin receptor, TRPV1, the vascular endothelial growth factor (VEGF) pathway, and cathelicidin LL-37, MMP-9, and KLKs. We evaluated the activity of four compounds (dextran sulfate, 4-t-butylcyclohexanol [BCH; TRP-regulin], pongamia oil, and hesperidin methyl chalcone [HMC]) on inflammatory and vascular responses implicated in rosacea. Read More

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https://www.dovepress.com/effects-of-dextran-sulfate-4-t-but
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http://dx.doi.org/10.2147/CCID.S168621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135068PMC
September 2018
7 Reads

Rosacea and Demodicosis: Little-known Diagnostic Signs and Symptoms.

Acta Derm Venereol 2018 Sep 18. Epub 2018 Sep 18.

Dermatology Clinic, Université Libre de Bruxelles, 1030 Bruxelles, Belgium.

Papulopustular rosacea and demodicosis are characterized by non-specific symptoms, which can make clinical diagnosis difficult. This retrospective study of 844 patients assessed the diagnostic importance of clinical signs and symptoms that are poorly recognized as being associated with these conditions. In addition to well-known signs (vascular signs (present in 80% of patients), papules (39%), pustules (22%) and ocular involvement (21%)), other signs and symptoms (discreet follicular scales (93%), scalp symptoms (pruritus, dandruff or folliculitis; 38%) and pruritus (15%)) may also suggest a diagnosis not only of demodicosis, but also of papulopustular rosacea. Read More

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http://www.medicaljournals.se/acta/content/abstract/10.2340/
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http://dx.doi.org/10.2340/00015555-3041DOI Listing
September 2018
2 Reads

Procedural management of rhinophyma: A comprehensive review.

J Cosmet Dermatol 2018 Dec 17;17(6):960-967. Epub 2018 Sep 17.

Department of Dermatology, University of Utah, Salt Lake City, Utah.

Background: Rhinophyma is a cosmetically deforming disease characterized by nodular overgrowth of the lower 2/3 of the nose and is considered the end stage of acne rosacea.

Aims: Review the spectrum of procedural techniques for treatment of rhinophyma with a focus on the advantages and disadvantages of each modality.

Methods: A comprehensive literature search was conducted using the search terms "rhinophyma," "treatment," and "surgery" in PubMed. Read More

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http://dx.doi.org/10.1111/jocd.12770DOI Listing
December 2018
1 Read

Subtyping, phenotyping or endotyping rosacea: how can we improve disease understanding and patient care?

Authors:
J P Thyssen

Br J Dermatol 2018 Sep;179(3):551-552

Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, 2900, Hellerup, Denmark.

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http://dx.doi.org/10.1111/bjd.16942DOI Listing
September 2018

Oxymetazoline Hydrochloride 1% Cream (Rhofade) for Persistent Facial Erythema Associated with Rosacea.

Am Fam Physician 2018 Jun;97(12):808-810

Carolinas Medical Center, Charlotte, NC, USA.

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June 2018
3 Reads

blepharitis: clinical perspectives.

Clin Optom (Auckl) 2018 4;10:57-63. Epub 2018 Jul 4.

Department of Clinical Education, Illinois College of Optometry, Chicago, IL, USA,

and are two mites which infest the human eye and which may, in excess, lead to a wide range of anterior segment findings. mites have been implicated in anterior and posterior blepharitis, blepharoconjunctivitis, blepharokeratitis, and beyond. Due to significant overlap with other anterior segment conditions, infestation remains underdiagnosed and undertreated. Read More

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https://www.dovepress.com/demodex-blepharitis-clinical-persp
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http://dx.doi.org/10.2147/OPTO.S142708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118860PMC
July 2018
11 Reads

Topical Steroid Damaged/Dependent Face (TSDF): A Study from a Tertiary Care Hospital in Eastern India.

Indian J Dermatol 2018 Sep-Oct;63(5):375-379

Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, India.

Background: Awareness against abuse of topical corticosteroids (TC), especially over the face, has been going on for last 5 years in India. In spite of that we are getting lots of cases in our hospitals.

Aims: The aims of this study were to ascertain the demographics, magnitude and clinical features of TC misuse on the face among the dermatology outpatient department (OPD) attendees and to analyze its causes. Read More

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http://dx.doi.org/10.4103/ijd.IJD_218_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124224PMC
September 2018
1 Read

A Prunus persica genome-wide RNA-seq approach uncovers major differences in the transcriptome among chilling injury sensitive and non-sensitive varieties.

Physiol Plant 2018 Sep 11. Epub 2018 Sep 11.

Centro de Biotecnología Vegetal, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Santiago, Chile.

Chilling injury represents a major constrain for crops productivity. Prunus persica, one of the most relevant rosacea crops, have early season varieties that are resistant to chilling injury, in contrast to late season varieties, which display chilling symptoms such as mealiness (dry, sandy fruit mesocarp) after prolonged storage at chilling temperatures. To uncover the molecular processes related to the ability of early varieties to withstand mealiness, postharvest and genome-wide RNA-seq assessments were performed in two early and two late varieties. Read More

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http://dx.doi.org/10.1111/ppl.12831DOI Listing
September 2018
2 Reads

Dermatoscopy of Granulomatous Disorders.

Dermatol Clin 2018 Oct 2;36(4):369-375. Epub 2018 Aug 2.

Department of Medical Area, Institute of Dermatology, University of Udine, Udine, Italy.

Although diagnosis of cutaneous granulomatous disorders (CGDs) is usually suspected based on morphologic findings, localization, and anamnestic data, clinical differentiation from each other and from similar dermatoses may be challenging. Recently, dermatoscopy has been demonstrated to be a useful tool for assisting the recognition of several CGDs. This article provides a current overview of the dermatoscopic features of the main noninfectious and infectious CGDs, including sarcoidosis, necrobiosis lipoidica, granuloma annulare, rheumatoid nodules, and leishmaniasis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07338635183107
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http://dx.doi.org/10.1016/j.det.2018.05.004DOI Listing
October 2018
7 Reads

Advances in Acne and Rosacea Therapy.

Semin Cutan Med Surg 2018 Jun;37(3S):S63-S66

Adjunct Professor Schulich School of Medicine and Dentistry Western University Windsor, Ontario, Canada.

New topical therapies have demonstrated efficacy in patients with moderate or severe acne who might otherwise have required therapy with systemic antibiotics or isotretinoin. Increasing knowledge about the pathogenesis of acne has facilitated the development of therapies with novel modes of action. New and investigational therapies also are available or in development for the treatment of both the papulopustular and erythematous manifestations of rosacea. Read More

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http://dx.doi.org/10.12788/j.sder.2018.025DOI Listing
June 2018
5 Reads

Efficient isolation and observation of the most complex human commensal, Demodex spp.

Exp Appl Acarol 2018 Sep 6;76(1):71-80. Epub 2018 Sep 6.

Department of Dermatology and Allergy, University Hospital, Ludwig-Maximilian-University Munich, Frauenlobstr. 9-11, 80337, Munich, Germany.

Demodex spp. mites are an often neglected member of the human skin microbiome. Mostly they are commensals, although their pathophysiological role in rosacea, spinulosis folliculorum, and other skin diseases is recognized. Read More

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http://dx.doi.org/10.1007/s10493-018-0289-0DOI Listing
September 2018

The role of nutrition in inflammatory pilosebaceous disorders: Implication of the skin-gut axis.

Australas J Dermatol 2018 Sep 3. Epub 2018 Sep 3.

Dermatology Division, Department of Medicine, University of Arizona, Tucson, Arizona, USA.

Nutrition plays a critical role in the manifestation and management of inflammatory pilosebaceous disorders. There is rich potential for insight into the impact of dietary effects on the pathophysiology of inflammatory pilosebaceous disorders including acne vulgaris, hidradenitis suppurativa, rosacea, and the closely related seborrhoeic dermatitis. Acne vulgaris and hidradenitis suppurativa are thought to have similar diet-modulating pathogenic pathways. Read More

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http://doi.wiley.com/10.1111/ajd.12909
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http://dx.doi.org/10.1111/ajd.12909DOI Listing
September 2018
13 Reads

Thiol/disulfide homeostasis as a marker of oxidative stress in rosacea: a controlled spectrophotometric study.

Cutan Ocul Toxicol 2018 Sep 3:1-15. Epub 2018 Sep 3.

d Department of Dermatology , Yildirim Beyazit University, Medical Faculty , Ankara , Turkey.

Background: Rosacea is the chronic inflammatory disease of the facial skin. Although its etiology is not clear yet, inflammatory processes triggered by oxidative stress and oxidation of lipids have been suggested to have a role. While studies on the relationship between inflammation and oxidative stress are ongoing, thiol metabolism and its role in oxidative stress have also begun to be investigated. Read More

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https://www.tandfonline.com/doi/full/10.1080/15569527.2018.1
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http://dx.doi.org/10.1080/15569527.2018.1517124DOI Listing
September 2018
11 Reads
0.920 Impact Factor

Expression of inflammatory and fibrogenetic markers in acne hypertrophic scar formation: focusing on role of TGF-β and IGF-1R.

Arch Dermatol Res 2018 Oct 29;310(8):665-673. Epub 2018 Aug 29.

Department of Dermatology, Seoul National University College of Medicine, Seoul, South Korea.

Acne vulgaris is a universal skin disease and it may leave a scar when the original skin lesion disappears. These scars can cause cosmetic problems and psychological burden, leading to poor quality of life of patients. Acne scars are classified into atrophic scars and hypertrophic scars. Read More

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http://link.springer.com/10.1007/s00403-018-1856-2
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http://dx.doi.org/10.1007/s00403-018-1856-2DOI Listing
October 2018
12 Reads

A Rare Dermatologic Disease in Pregnancy: Rosacea Fulminans- Case Report and Review of the Literature.

Open Access Maced J Med Sci 2018 Aug 4;6(8):1438-1441. Epub 2018 Aug 4.

Clinic of Obstetrics and Gynecology, Istanbul School of Medicine, Istanbul University, Istanbul, Turkey.

Background: Rosacea is a common, chronic disorder that can present with a variety of cutaneous or ocular manifestations. Skin involvement primarily affects the central face, with findings such as persistent centrofacial redness, papules, pustules, flushing, telangiectasia, and phymatous skin changes. The pathways that lead to the development of rosacea are not well understood. Read More

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http://dx.doi.org/10.3889/oamjms.2018.267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108794PMC

Head-and-neck dermatitis: Diagnostic difficulties and management pearls.

Pediatr Dermatol 2018 Nov 28;35(6):748-753. Epub 2018 Aug 28.

Division of Dermatology, Department of Medicine, University of Arizona, Tucson, Arizona.

Head-and-neck dermatitis is a variant of atopic dermatitis (AD) often seen in children and is challenging to diagnose, as it frequently overlaps with other eczematous dermatoses. Successful head-and-neck dermatitis (HND) treatment requires identification of common triggers and clinical mimickers, such as airborne dermatitis, periorificial dermatitis, and steroid-induced rosacea. Head-and-neck involvement negatively impacts quality of life and is often harder to treat than other body parts, as long-term topical corticosteroid use carries higher risks for skin atrophy on the face. Read More

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http://doi.wiley.com/10.1111/pde.13642
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http://dx.doi.org/10.1111/pde.13642DOI Listing
November 2018
21 Reads

The investigation of the relationships of demodex density with inflammatory response and oxidative stress in rosacea.

Arch Dermatol Res 2018 Nov 27;310(9):759-767. Epub 2018 Aug 27.

Department of Dermatology, Ağrı State Hospital, Ağrı, Turkey.

The relationships of demodex density with systemic oxidative stress, inflammatory response, and clinical severity in rosacea are not clear. This study aimed to (a) analyze the levels of systemic oxidative stress, antioxidant capacity, inflammatory parameters, and matrix metalloproteinases (MMPs) in systemic circulation in patients with rosacea, (b) identify the relationship between mite density and both oxidative stress and inflammation, and (c) investigate the role of photoaging and sebum secretion in etiopathogenesis. Forty patients with rosacea and 40 age-, sex-, and skin phenotype-matched healthy volunteers were included in the study. Read More

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http://dx.doi.org/10.1007/s00403-018-1857-1DOI Listing
November 2018
1 Read

Effectiveness of photopneumatic technology: a descriptive review of the literature.

Lasers Med Sci 2018 Nov 24;33(8):1631-1637. Epub 2018 Aug 24.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave., 2nd Floor, Unit 2099, Sylvester Comprehensive Cancer Center, Miami, FL, 33136, USA.

Usage of photopneumatic technology has recently increased for treatment of different skin conditions such as acne, keratosis pilaris (KP), and rosacea. Photopneumatic devices combine gentle negative pressure with broad band pulsed light simultaneously to attack multiple targets in the skin for better treatment outcomes. In this literature review, we evaluate the efficacy of photopneumatic therapy on treatment of acne, keratosis pilaris (KP), and rosacea. Read More

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http://link.springer.com/10.1007/s10103-018-2619-1
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http://dx.doi.org/10.1007/s10103-018-2619-1DOI Listing
November 2018
15 Reads

Treatment of Rosacea using acupuncture for improving the local skin microcirculation: A case report.

Medicine (Baltimore) 2018 Aug;97(34):e11931

South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine.

Rationale: Rosacea is an irritating disease that affects patients' health and life quality. The current treatments for rosacea have limited efficacy and are generally not satisfying most patients. This report presents a patient diagnosed with rosacea who was treated with acupuncture to a satisfactory effect. Read More

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http://dx.doi.org/10.1097/MD.0000000000011931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113042PMC
August 2018
4 Reads

Elevated Tear Human Neutrophil Peptides 1-3, Human Beta Defensin-2 Levels and Conjunctival Cathelicidin LL-37 Gene Expression in Ocular Rosacea.

Ocul Immunol Inflamm 2018 Aug 24:1-10. Epub 2018 Aug 24.

c Vocational High School of Health Services, Department of Medical Services and Techniques , Kırıkkale University , Kırıkkale , Turkey.

Purpose: To investigate the role of innate immunity in ocular rosacea.

Methods: Thirty-two patients with ocular rosacea patients (group-1) and 28 healthy volunteers (group-2) who served as controls were enrolled in the study. Tear function parameters were assessed, conjunctival impression cytology was performed and tear samples were collected. Read More

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https://www.tandfonline.com/doi/full/10.1080/09273948.2018.1
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http://dx.doi.org/10.1080/09273948.2018.1504971DOI Listing
August 2018
7 Reads

The worldwide epidemiology of rosacea.

Authors:
R Parisi Z Z N Yiu

Br J Dermatol 2018 Aug;179(2):239-240

Centre for Pharmacoepidemiology and Drug Safety, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, U.K.

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http://dx.doi.org/10.1111/bjd.16788DOI Listing
August 2018
3 Reads

Screening for depression in rosacea patients.

Cutis 2018 Jul;102(1):36-38

Departments of Pathology and Public Health Sciences, Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

Rosacea patients often are burdened with embarrassment, social anxiety, and psychiatric comorbidities. The Patient Health Questionnaire 9 (PHQ-9) is a validated and reliable self-administered tool for diagnosis of depression and designation of depression severity. This study aimed to examine the relationship between rosacea severity scores and level of depression using a validated rosacea self-assessment tool and the PHQ-9, respectively. Read More

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July 2018
1 Read
0.590 Impact Factor