31,182 results match your criteria Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie[Journal]


Nanoscale Imaging of Kidney Glomeruli Using Expansion Pathology.

Front Med (Lausanne) 2018 21;5:322. Epub 2018 Nov 21.

Department of Biological Sciences, Mellon College of Science, Carnegie Mellon University, Pittsburgh, PA, United States.

Kidney glomerular diseases, such as the minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS), and other nephrotic syndromes, are typically diagnosed or confirmed via electron microscopy. Although optical microscopy has been a vital tool to examine clinical specimens for diagnoses in pathology for decades, the optical resolution is constricted by the physical diffraction limit of the optical microscope, which prevents high-resolution investigation of subcellular anatomy, such as of the podocyte tertiary foot processes. Here, we describe a simple, fast, and inexpensive protocol for nanoscale optical imaging of kidney glomeruli. Read More

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November 2018
1 Read

Extensively drug-resistant and association in a Romanian intensive care unit: risk factors for acquisition.

Infect Drug Resist 2018 8;11:2187-2197. Epub 2018 Nov 8.

Victor Babeș University of Medicine and Pharmacy, Timisoara, Romania,

Purpose: The purpose of this study was to identify risk factors for extensively drug-resistant (XDR) (AB) and XDR association in the largest intensive care unit (ICU) in Western Romania.

Materials And Methods: This retrospective case-controlled study was conducted between January 2016 and December 2016 in the ICU of the "Pius Brînzeu" County Emergency Clinical Hospital of Timi oara. Data were collected, in strict confidentiality, from the electronic database of the Microbiology Laboratory and the hospital's electronic medical records. Read More

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November 2018

Adsorption of Sb (III) on Oxidized Exfoliated Graphite Nanoplatelets.

Nanomaterials (Basel) 2018 Nov 30;8(12). Epub 2018 Nov 30.

Faculty of Applied Chemistry and Material Science, University Politehnica of Bucharest, 313 Splaiul Independentei Street, 060042 Bucharest, Romania.

In this work, Sb (III) adsorption on oxidized exfoliated graphite nanoplatelets (ox-xGnP) was evaluated for the first time, to the best of our knowledge. The ox-xGnP were characterized by thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FT-IR), Brunauer⁻Emmet⁻Teller (BET) analysis, scanning electron microscopy (SEM), transmission electron microscopy (TEM) equipped with energy-dispersive X-ray spectroscopy (EDX), and Zeta potential analysis. The adsorption parameters, such as pH and contact time, were optimized, and the best adsorption capacity obtained was 8. Read More

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November 2018

Correlation between disease severity and quality of life in patients with epidermolysis bullosa.

J Eur Acad Dermatol Venereol 2018 Nov 25. Epub 2018 Nov 25.

"Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca.

There is an increased interest of medical staff to have a more objective evidence of the severity of clinical picture of the patient with epidermolysis bullosa (EB), but also about the patient's quality of life. The goal of these studies is to develop a personalized treatment, based on the patients' needs. The aims of our study were to develop a validated and reliable quality of life questionnaire (QOLEB) in Romania, to assess the health-related quality of life (HRQoL) in Romanian EB patients, and to perform an objective evaluation of the clinical features of patients with EB. Read More

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November 2018
3 Reads

Next-generation sequencing-based characterization of the invasion by anatomical contiguity in a primary osseous diffuse large B-cell lymphoma. Correlation between the genetic profile of the malignancy and the clinical outcome of the patient.

Histol Histopathol 2018 Nov 23:18067. Epub 2018 Nov 23.

Research Center for Functional Genomics, Biomedicine and Translational Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Primary bone lymphoma is now a well-described entity in the World Health Organization (WHO) Classification of Tumors of Soft Tissue and Bone as a malignancy of the lymphoid tissue, with at least one mass within bone, without involvement of supraregional lymph nodes or other extranodal sites. In the current paper, we describe the complete characterization of the mutational landscape of a diffuse large B cell non-Hodgkin's lymphoma (DLBLCL) of the tibial plateau. Currently, there is very little data about the genetic landscape of primary osseous lymphomas and about the genetic background of this type of malignancy, resistant to chemotherapy and invading the surrounding tissues. Read More

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November 2018
2 Reads

Synthesis and characterization of a polyurethane carrier used for a prolonged transmembrane transfer of a chili pepper extract.

Int J Nanomedicine 2018 6;13:7155-7166. Epub 2018 Nov 6.

The 5th Department (Internal Medicine I), Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.

Purpose: Red chili peppers have been highly valued in gastronomy and traditional medicine since ancient times; it seems that it is not just an ingredient for food but also a good remedy for various medical conditions such as increased blood pressure and high levels of serum triglycerides and cholesterol, myocardial infarction, arthritis, and migraines. The objective of this study is the characterization of a new carrier used for encapsulated extract.

Methods: Chili pepper extract was obtained and was physically entrapped inside polyurethane microparticles in order to diminish the irritative potential of this extract. Read More

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November 2018
5 Reads

Prevalence of the fabella and its association with pain in the posterolateral corner of the knee: A cross-sectional study in a Romanian population.

Medicine (Baltimore) 2018 Nov;97(47):e13333

Department of Anatomy and Embryology, University of Medicine and Pharmacy of Tîrgu Mureş, Romania.

The functions and clinical consequences of the fabella, a sesamoid bone found in the posterolateral aspect of the knee joint, are still a reason of intense debate in the scientific literature. Its incidence was reported to range between 20% and 87% and its presence was usually associated with the persistent pain in the posterolateral region of the knee. The aim of our study was to measure the prevalence, anatomic and clinical features of the fabella within a cross-sectional study, conducted in a Romanian orthopaedic center. Read More

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November 2018
1 Read

Green route for the fabrication of self-healable hydrogels based on tricarboxy cellulose and poly(vinyl alcohol).

Int J Biol Macromol 2018 Nov 17;123:744-751. Epub 2018 Nov 17.

"Petru Poni" Institute of Macromolecular Chemistry, Romanian Academy, 41 A, Gr. Ghica Voda Alley, 700487 Iasi, Romania. Electronic address:

A new approach for the preparation of poly (vinyl alcohol) (PVA) - cellulose based composite hydrogels by freezing/thawing method was conceived. We synthesized firstly the tricarboxy cellulose (OxC) (bearing three carboxyl groups in one anhydroglucose unit) using a one shot oxidation procedure and subsequently, the aqueous solutions of OxC were mixed with PVA solutions in different ratios, in the absence of any supplementary cross-linking agent. The spectral methods, FTIR, H, C NMR, as well as rheology measurements were used to assess the degree of interaction between the two components. Read More

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November 2018

A continuous-time MaxSAT solver with high analog performance.

Nat Commun 2018 Nov 19;9(1):4864. Epub 2018 Nov 19.

Faculty of Physics, Babeş-Bolyai University, Cluj-Napoca, 400084, Romania.

Many real-life optimization problems can be formulated in Boolean logic as MaxSAT, a class of problems where the task is finding Boolean assignments to variables satisfying the maximum number of logical constraints. Since MaxSAT is NP-hard, no algorithm is known to efficiently solve these problems. Here we present a continuous-time analog solver for MaxSAT and show that the scaling of the escape rate, an invariant of the solver's dynamics, can predict the maximum number of satisfiable constraints, often well before finding the optimal assignment. Read More

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November 2018
6 Reads

Effects of preconditioning hamstring resistance exercises on repeated sprinting-induced muscle damage in female soccer players.

Biol Sport 2018 Sep 27;35(3):269-275. Epub 2018 Aug 27.

Department of Health, Exercise Science, and Recreation Management, The University of Mississippi, University, MS 38677, USA.

To examine whether adding preconditioning hamstring resistance exercises to a regular warm-up prior to a repeated sprinting exercise provides protection against the sprinting-induced muscle damage. Ten female soccer players (mean ± SD age: 21.3 ± 4. Read More

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September 2018
2 Reads

The impact of political, socio-economic and cultural factors on implementing environment friendly techniques for sustainable land management and climate change mitigation in Romania.

Sci Total Environ 2018 Nov 12;654:418-429. Epub 2018 Nov 12.

Department of Physical Geography, Stockholm University, SE-106 91 Stockholm, Sweden.

Throughout the history of Romania, political decisions, socio-economic measures, and cultural (traditional) characters have affected the implementation of environment friendly techniques (EFTs) policies. In the context of this paper, EFTs can be defined as solutions for the use of land resources aiming the increasing of goods for meeting the changing human needs and with neutral or positive environmental impact. Changes in the political regime have always had a visible impact on the EFTs issue in Romania. Read More

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November 2018
2 Reads

Cisplatin Loaded Multiwalled Carbon Nanotubes Induce Resistance in Triple Negative Breast Cancer Cells.

Pharmaceutics 2018 Nov 13;10(4). Epub 2018 Nov 13.

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, 91-95 Splaiul Independentei, R-050095 Bucharest, Romania.

In this paper we developed a method for multiwalled carbon nanotubes (MWCNTs) use as carriers for a drug based on platinum in breast cancer therapy. The method of functionalization involves the carboxyl functionalization of nanotubes and encapsulation of cisplatin (CDDP) into MWCNTs. The biological properties of MWCNTs loaded with CDDP (MWCNT-COOH-CDDP) and of individual components MWCNT-COOH and free CDDP were evaluated on MDA-MB-231 cells. Read More

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November 2018

A multicenter cross-sectional study of episiotomy practice in Romania.

J Eval Clin Pract 2018 Nov 13. Epub 2018 Nov 13.

Department of Obstetrics Gynecology and Neonatology, "Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania.

Rationale, Aims, And Objectives: The aim of this study was to focus attention on episiotomy practice in Romanian maternity units in order to identify factors associated with the very high rate of the procedure in Romania and to consider strategies to reduce it.

Methods: In this clustered cross-sectional study, a total of 11 863 patients were recorded in eight Romanian maternity units to assess the prevalence of episiotomy. A random effects Poisson model was used to estimate the prevalence rate in univariate and multivariate models. Read More

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November 2018
2 Reads
1.580 Impact Factor

Floating-Harbor Syndrome: Presentation of the First Romanian Patient with a Mutation and Review of the Literature.

Balkan J Med Genet 2018 Jun 29;21(1):83-86. Epub 2018 Oct 29.

Institute of Human Genetics, University Medical Center Göttingen, Göttingen, Germany.

Floating-Harbor syndrome (FHS) is a rare autosomal dominant syndrome characterized by short stature with delayed bone age, retarded speech development, intellectual disability and dysmorphic facial features. Recently, dominant mutations almost exclusively clustered in the final exon of the Snf2-related CREBBP activator protein () gene were identified to cause FHS. Here, we report a boy with short stature, speech delay, mild intellectual disability, dysmorphic features, and with genetically confirmed FHS. Read More

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June 2018
3 Reads

Consequences of Misdiagnosed and Mismanaged Hereditary Angioedema Laryngeal Attacks: An Overview of Cases from the Romanian Registry.

Case Rep Emerg Med 2018 22;2018:6363787. Epub 2018 Oct 22.

Romanian Network for Hereditary Angioedema, 11a Sântana St, 540256 Tîrgu-Mureş, Romania.

Emergency department (ED) physicians frequently encounter patients presenting with angioedema. Most of these involve histamine-mediated angioedema; however, less common forms of angioedema (bradykinin-mediated) also occur. It is vital physicians correctly recognize and treat this; particularly since bradykinin-mediated angioedema does not respond to antihistamines, corticosteroids or epinephrine and hereditary angioedema (HAE) laryngeal attacks can be fatal. Read More

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October 2018
1 Read

Rates and Causes of Death among Adult Diabetes Patients in Romania.

Endocr Res 2018 Nov 13:1-6. Epub 2018 Nov 13.

a Endocrinology and diabetes , "Carol Davila" University of Medicine and Pharmacy , Bucharest , Romania.

Aims: To study the age and sex-dependent mortality rates and causes of death in a large Romanian diabetes cohort as compared with the general population.

Methods: All adult patients aged 20-64 years, receiving a free diabetes prescription in a major urban area during 2001-2008 were included and followed-up for death until December 31, 2011. Crude mortality rates and standardized mortality rate ratios (SMR) against general population (data from the National Institute of Statistics) were calculated. Read More

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November 2018
3 Reads

Collagen-Polyvinyl Alcohol-Indomethacin Biohybrid Matrices as Wound Dressings.

Pharmaceutics 2018 Nov 9;10(4). Epub 2018 Nov 9.

Center of Surface Science and Nanotechnology, University Politehnica of Bucharest, 060042 Splaiul Independentei 313, Romania.

The aim of this study is to design, develop and evaluate new biohybrid sponges based on polymers (collagen and polyvinyl alcohol) with and without indomethacin as anti-inflammatory drug model to be used for tissue regeneration in wound healing. Type I fibrillar collagen in the form of a gel and different concentrations of polyvinyl alcohol were mixed together to prepare composite gels. Both control samples, without indomethacin and with indomethacin, were obtained. Read More

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November 2018
4 Reads

Co-delivery of curcumin and doxorubicin in PEGylated liposomes favored the antineoplastic C26 murine colon carcinoma microenvironment.

Drug Deliv Transl Res 2018 Nov 12. Epub 2018 Nov 12.

Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, University of Medicine and Pharmacy "Iuliu Hatieganu", 41 Victor Babes Str., 400012, Cluj-Napoca, Romania.

Our recent studies have demonstrated that the antitumor efficacy of doxorubicin (DOX), administered in long-circulating liposomes (LCL), could be considerably improved after its co-encapsulation with curcumin (CURC). Thus, the question addressed within this article is whether LCL-CURC-DOX can be exploited more efficiently than liposomal DOX for future colorectal cancer therapy. Therefore, we investigated the physicochemical and biological properties of LCL-CURC-DOX and the mechanisms of its antitumor activity in C26 murine colon carcinoma in vivo. Read More

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November 2018
2 Reads

Attitude, knowledge and informed choice towards prenatal screening for Down Syndrome: a cross-sectional study.

BMC Pregnancy Childbirth 2018 Nov 12;18(1):439. Epub 2018 Nov 12.

Department of Medical Genetics, "Iuliu Haţieganu" University of Medicine and Pharmacy, Pasteur Louis Street No.6, 400349, Cluj-Napoca, Romania.

Background: Down Syndrome screening test is a bridge between knowledge and uncertainty, safety and risk, unpredictability and desire to know in order to gain control. It may be accepted either not to have a baby with Down syndrome, or to prepare to have a baby with this condition. Every woman should understand that it is an option and should be encouraged to make their own decisions based on information and personal values. Read More

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November 2018
3 Reads

Natural decay of archaeological oak wood versus artificial degradation processes - An FT-IR spectroscopy and X-ray diffraction study.

Spectrochim Acta A Mol Biomol Spectrosc 2019 Feb 1;209:280-287. Epub 2018 Nov 1.

Petru Poni Institute of Macromolecular Chemistry of the Romanian Academy, Iasi, Romania; Centre of Wood Science and Technology, Edinburgh Napier University, Edinburgh, UK. Electronic address:

Wood has been extensively used as a material for different applications over the years, therefore the understanding of different degradation processes in various environments is of great importance. In this study, the infrared spectroscopy, X-ray diffraction and chemometric methods were used to evaluate and compare the structure of archaeological and artificially degraded oak wood. The results clearly show that modifications in the structure of archaeological wood are related to the position of the material in the log (sapwood and heartwood), thus the extent of wood degradation. Read More

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February 2019

Zwitterionic Cysteine Drug Coating Influence in Functionalization of Implantable Ti50Zr Alloy for Antibacterial, Biocompatibility and Stability Properties.

Pharmaceutics 2018 Nov 8;10(4). Epub 2018 Nov 8.

Faculty of Applied Chemistry and Materials Science POLITEHNICAof Bucharest, Romania Str. Polizu1-7, 011061 Bucharest, Romania.

The present paper aims atincreasing the bioperformance of implantable Ti50Zr alloy using zwitterionic cysteine drug coating. Aspects such as stability, biocompatibility, and antibacterial effects were investigated with the help of various methods such as infrared spectroscopy (FT-IR), scanning electronic microscopy (SEM), electrochemical methods, contact angle determinations and cell response. The experimental data of zwitterionic cysteine coating indicate the existence of a hydration layer due to hydrophilic groups evidenced in FT-IR which is responsible for the decrease of contact angle and antibacterial capabilities. Read More

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November 2018
6 Reads

Molecular ejection transition in liquid crystal columns self-assembled from wedge-shaped minidendrons.

Soft Matter 2018 Nov 9. Epub 2018 Nov 9.

Department of Physics, Zhejiang Sci-Tech University, Xiasha College Park, Hangzhou 310018, China and Department of Materials Science and Engineering, University of Sheffield, Sheffield S1 3JD, UK.

Fan-shaped molecules with aromatic head-groups and two or more flexible pendant chains often self-assemble into columns that form columnar liquid crystals by packing on a 2d lattice. Such dendrons or minidendrons are essential building blocks in a large number of synthetic self-assembled systems and organic device materials. Here we report a new type of phase transition that occurs between two hexagonal columnar phases, Colh1 and Colh2, of Na-salt of 3,4,5-tris-dodecyloxy benzoic acid. Read More

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November 2018
1 Read

Impact of quorum sensing signaling molecules on adhesion and inflammatory markers in endothelial cells.

Beilstein J Org Chem 2018 5;14:2580-2588. Epub 2018 Oct 5.

University of Bucharest, Faculty of Biology, Department of Microbiology-Immunology, Bucharest, Romania.

relies on the quorum sensing (QS) signaling system as a central regulator mechanism of virulence expression that contributes to the formation and maintenance of biofilms and tolerance to conventional antimicrobials. QS Signaling molecules (QSSMs) may be recognized and may function also within the host cells, being potentially involved in the progression of the infectious process. In this study we evaluate the expression of adhesion and inflammatory molecules in endothelial cells treated with QSSMs, in order to bring new insights on the mechanisms involved in the interaction of with host cells during the infectious process. Read More

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October 2018
2 Reads

Performances of Pichia kudriavzevii in decolorization, biodegradation, and detoxification of C.I. Basic Blue 41 under optimized cultural conditions.

Environ Sci Pollut Res Int 2018 Nov 7. Epub 2018 Nov 7.

Department of Experimental and Applied Biology, NIRDBS-Institute of Biological Research Iasi, Lascar Catargi 47, 700107, Iasi, Romania.

The aim of this study was to evaluate the performances of Pichia kudriavzevii CR-Y103 yeast strain for the decolorization, biodegradation, and detoxification of cationic dye C.I. Basic Blue 41, a toxic compound to aquatic life with long-lasting effects. Read More

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November 2018
3 Reads

Conservation priorities for terrestrial mammals in Dobrogea Region, Romania.

Zookeys 2018 23(792):133-158. Epub 2018 Oct 23.

University of Bucharest, Center for Environmental Research and Impact Studies, 1 N. Balcescu, 010041, Bucharest, Romania.

Based on species occurrence records of museum collections, published literature, and unpublished records shared by mammalian experts, we compiled a distribution database for 59 terrestrial mammals populating the extensively protected Dobrogea Region of Romania. The spatial patterns of mammal distribution and diversity was evaluated and systematic conservation planning applied to identify priority areas for their conservation. The spatial analyses revealed that intensive sampling was not directly correlated to mammal diversity but rather to accessibility for inventory. Read More

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October 2018
3 Reads

Lifestyles and discomfort in a sample of young Romanian students.

J Prev Med Hyg 2018 Sep 28;59(3):E230-E235. Epub 2018 Sep 28.

School of Medicinal and Health Products Sciences, University of Camerino, Italy.

Introduction: The 40.3% of the Romanian youth population is at risk of poverty or social exclusion, and, in addition, the abuse of substances increases. It was interesting to evaluate the attitudes shared by pupils as well as their knowledge of these substances with a view to analyzing causes and types of risky behaviour in young people. Read More

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September 2018
1 Read

In-situ Star Formation in the Outskirts of the Large Magellanic Cloud: DR2 Confirmation.

Astrophys J 2018 Jul;862(1)

Astronomy Department, Yale University, 46 Hillhouse Avenue, New Haven, CT 06511, USA.

We explore the data release 2 (DR2) proper motions of six young, main-sequence stars, members of the Large Magellanic Cloud (LMC) reported by Moni Bidin et al. These stars are located in the outskirts of the disk, between 7° and 13° from the LMC's center where there is very low H I content. DR2 proper motions confirm that four stars formed locally, in situ, while two are consistent with being expelled via dynamical interactions from inner, more gas-rich regions of the LMC. Read More

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Description of a new species of from Albania, with consideration of the eastern Mediterranean as a diversity hotspot (Diptera, Tipulidae).

Zookeys 2018 23(792):99-115. Epub 2018 Oct 23.

Romanian Academy Institute of Biology, Splaiul Independenţei 296, 060031 Bucureşti, Romania Romanian Academy Institute of Biology Bucureşti Romania.

A new species of the TipulasubgenusMediotipula is described from the south-eastern part of Albania, south-eastern Europe. Morphologically, the new species is most similar to T. (M. Read More

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October 2018

Corrigendum to "Serological evidence for avian H9N2 influenza virus infections among Romanian agriculture workers" [J. Infect. Public Health 6 (2013) 438-447].

J Infect Public Health 2018 Nov - Dec;11(6):902

College of Public Health and Health Professions, and Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA. Electronic address:

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November 2018
2 Reads

Studies on the in vivo metabolism of the SARM YK11: Identification and characterization of metabolites potentially useful for doping controls.

Drug Test Anal 2018 Oct 31. Epub 2018 Oct 31.

German Sport University Cologne, Center for Preventive Doping Research, Am Sportpark Müngersdorf 6, 50933, Cologne, Germany.

A steroidal compound was recently detected in a seized black market product and was identified as (17α,20E)-17,20-[(1-methoxyethylidene) bis (oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11). This compound is described to possess selective androgen receptor modulator- and myostatin inhibitor-like properties. As YK11 is an experimental drug candidate and a non-approved substance for humans, scientific data on its metabolism is scarce. Read More

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October 2018

Areas of Cartilaginous and Osseous Metaplasia After Experimental Myocardial Infarction in Rats.

Anat Rec (Hoboken) 2018 Oct 28. Epub 2018 Oct 28.

Histology Department, "Carol Davila" University of Medicine and Pharmacy, 8 Eroilor Sanitari Blvd., 050474, Bucharest, Romania.

The presence of hyaline cartilage has been previously documented in heart tissue of different vertebrates, ranging from birds to superior mammals. However, there is scarce published data regarding the appearance of focal deposits of hyaline-like cartilage within the hearts of laboratory rats. Few mechanisms that could trigger the appearance of this type of cartilage in heart were hypothesized (e. Read More

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October 2018
1 Read

Nitrosalicyl-imine-chitosan hydrogels based drug delivery systems for long term sustained release in local therapy.

J Colloid Interface Sci 2019 Feb 19;536:196-207. Epub 2018 Oct 19.

"Petru Poni" Institute of Macromolecular Chemistry of Romanian Academy, Iasi, Romania. Electronic address:

The paper focuses on the synthesis and characterization of new drug delivery systems for local therapy. They were prepared by in situ hydrogelation of chitosan biopolymer with nitrosalicylaldehyde in the presence of a model drug, varying the crosslinking density. The structural, supramolecular and morphological characteristics of the systems were studied by FTIR spectroscopy, X-ray diffraction and, POM and SEM microscopy. Read More

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February 2019

West Nile virus lineage 2 in Romania, 2015-2016: co-circulation and strain replacement.

Parasit Vectors 2018 Oct 26;11(1):562. Epub 2018 Oct 26.

Cantacuzino National Medico-Military Institute for Research and Development, 103 Splaiul Independenței, 050096, Bucharest, Romania.

Background: West Nile virus (WNV) is endemic in southeastern Romania and, after the unprecedented urban epidemic in Bucharest in 1996 caused by lineage 1 WNV, cases of West Nile fever have been recorded every year. Furthermore, a new outbreak occurred in 2010, this time produced by a lineage 2 WNV belonging to the Eastern European clade (Volgograd 2007-like strain), which was detected in humans and mosquitoes in the following years.

Results: We report here, for the first time, the emergence, in 2015, of lineage 2 WNV belonging to the monophyletic Central/Southern European group of strains which replaced in 2016, the previously endemized lineage 2 WNV Volgograd 2007-like strain in mosquito populations. Read More

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October 2018
6 Reads

The Relationship Between Psychosocial Status and Hypertensive Condition.

Curr Hypertens Rep 2018 Oct 25;20(12):102. Epub 2018 Oct 25.

Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

Purpose Of Review: The aim of the paper is to test the influence of social status and psychological well-being (independent variables) on hypertensive condition (dependent variable), when adjusting for traditional risk factors of cardiovascular disease (control variables). The analysis is based on data collected from SEPHAR III, a nationally representative epidemiologic study of the Romanian adult population.

Recent Findings: Understanding the social roots of health issues is of considerable importance in developing effective strategies and policies. Read More

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October 2018
5 Reads

Cationic Substitutions in Hydroxyapatite: Current Status of the Derived Biofunctional Effects and Their In Vitro Interrogation Methods.

Materials (Basel) 2018 Oct 24;11(11). Epub 2018 Oct 24.

National Institute of Materials Physics, RO-077125 Magurele, Romania.

High-performance bioceramics are required for preventing failure and prolonging the life-time of bone grafting scaffolds and osseous implants. The proper identification and development of materials with extended functionalities addressing socio-economic needs and health problems constitute important and critical steps at the heart of clinical research. Recent findings in the realm of ion-substituted hydroxyapatite (HA) could pave the road towards significant developments in biomedicine, with an emphasis on a new generation of orthopaedic and dentistry applications, since such bioceramics are able to mimic the structural, compositional and mechanical properties of the bone mineral phase. Read More

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October 2018
6 Reads

Mapping cancer research across Central and Eastern Europe, the Russian Federation and Central Asia: Implications for future national cancer control planning.

Eur J Cancer 2018 Nov 20;104:127-136. Epub 2018 Oct 20.

Institute of Cancer Policy, Cancer Epidemiology, Population & Global Health, School of Cancer Sciences, King's College London & Guy's & St.Thomas' NHS Trust, London, UK. Electronic address:

Cancer research is an essential part of national cancer control programmes, and the emerging economies of Central and Eastern Europe (CEE) and the Russian Federation and Central Asia (R-CA) (Commonwealth of Independent States) remain relatively understudied. Here, we map the cancer research activity from the 29 countries across these regions over a 10-year period (2007-2016), using a standard scientometric approach. Research activity was compared with the countries' wealth and with the disease burden from different cancers, and analyses were also performed by the research domain (e. Read More

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November 2018
1 Read

A new feather mite species of the genus Canestrini, 1899 (Acarina, Trouessartiidae) - an integrative description (morphology and DNA barcoding data).

Zookeys 2018 10(789):19-35. Epub 2018 Oct 10.

"Grigore Antipa" National Museum of Natural History, Sos. Kiseleff no.1, 011341 Bucharest 1, Romania "Grigore Antipa" National Museum of Natural History Bucharest Romania.

A new species of the feather mite genus (Trouessartiidae) is described from the Large Niltava (Blyth) (Passeriformes, Muscicapidae) in Northeast India (Meghalaya, Jaintia Hills, Shnongrim village). Constantinescu, is morphologically closely related (no phylogenetic meaning) to Gaud, 1968 from (Mayr) (Passeriformes: Monarchidae), sharing in males a unique character within the genus, by having setae on legs IV hemispheroid, with spine-shaped apex. Males of the new species have the prodorsal shield without ornamentation, the prohysteronotal shield and lobar shield connected, and the terminal cleft parallel sided. Read More

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October 2018
1 Read

The Fructoborates: Part of a Family of Naturally Occurring Sugar-Borate Complexes-Biochemistry, Physiology, and Impact on Human Health: a Review.

Biol Trace Elem Res 2018 Oct 20. Epub 2018 Oct 20.

Department of Pharmacognosy & Phytotherapy, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, 2 Petru Rareş Street, 200349, Craiova, Romania.

Sugar-borates (SBs) are mono- or di-sugar-borate esters (SBEs) comprised of one or two monosaccharide molecules linked to a boron (B) atom. SBEs occur naturally in commonly consumed herbs, vegetables, fruits, seeds, and nuts and, other than greatly varying levels of B found in local drinking water, are the primary natural dietary sources of B-containing molecules in humans. To date, the most studied SBE is calcium fructoborate (CaFB). Read More

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October 2018
10 Reads

Characterizing forensically important insect and microbial community colonization patterns in buried remains.

Sci Rep 2018 Oct 19;8(1):15513. Epub 2018 Oct 19.

Institute of Biology Bucharest, Romanian Academy, Splaiul Independentei, 296, 060031, Bucharest, Romania.

During violent criminal actions in which the perpetrator disposes of the victim's remains by burial, the analysis of insects and bacterial colonization patterns could be necessary for postmortem interval (PMI) estimation. Our research aimed to assess the decomposition process of buried rat carcasses from shallow graves (40 cm), the diversity and dynamics of insects and bacteria throughout the decomposition stages, and the environmental parameters' influence on these variations. The results provide further insight on decomposition in soil and contribute to a broader understanding of the factors involved in decomposition by qualitatively and quantitatively analysing the decomposer community (bacteria and insects). Read More

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October 2018

Cellulose defibrillation and functionalization by plasma in liquid treatment.

Sci Rep 2018 Oct 19;8(1):15473. Epub 2018 Oct 19.

National Institute for Laser, Plasma and Radiation Physics, Atomistilor 409, Magurele, Bucharest, Ilfov, 077125, Romania.

Submerged liquid plasma (SLP) is a new and promising method to modify powder materials. Up to now, this technique has been mostly applied to carbonaceous materials, however, SLP shows great potential as a low-cost and environmental-friendly method to modify cellulose. In this work we demonstrate the modification of microcrystalline cellulose (MCC) by applying the SLP combined with ultrasonication treatments. Read More

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October 2018
6 Reads

Zinc Oxide Spherical-Shaped Nanostructures: Investigation of Surface Reactivity and Interactions with Microbial and Mammalian Cells.

Langmuir 2018 Nov 2;34(45):13638-13651. Epub 2018 Nov 2.

"Ilie Murgulescu" Institute of Physical Chemistry , Romanian Academy , 202 Splaiul Independentei , 060021 Bucharest , Romania.

Two ZnO materials of spherical hierarchical morphologies, with hollow (ZnO) and solid cores (ZnO), were obtained through the hydrolysis of zinc acetylacetonate in 1,4-butanediol. The nature of the defects and surface reactivity for the two ZnO materials were investigated through photoluminescence, X-ray photoelectron spectroscopy, and electron paramagnetic resonance (EPR) spectroscopy proving the coexistence of shallow and deep defects and, also, the presence of polyol byproducts adsorbed on the outer layers of the ZnO samples. The EPR spectroscopy coupled with the spin-trapping technique showed that the surface of the ZnO samples generates reactive oxygen species (ROS) like hydroxyl (OH) and singlet oxygen (O) as well as carbon-centered radicals. Read More

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November 2018
4 Reads

Enhancing Molecular Promiscuity Evaluation Through Assay Profiles.

Pharm Res 2018 Oct 18;35(11):240. Epub 2018 Oct 18.

Department of Computational Chemistry, Institute of Chemistry Timisoara of Romanian Academy, 24 Mihai Viteazu Blvd, Timişoara, Timiş, 300223, România.

Purpose: The growing amount of heterogeneous bioactivity data requires effective strategies to assess the promiscuity/selectivity of small-molecules and aid drug discovery. In the current study, we aim to evaluate the potential of assay profiles (APs, i.e. Read More

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October 2018
4 Reads

Dogs accompanied humans during the Neolithic expansion into Europe.

Biol Lett 2018 Oct 17;14(10). Epub 2018 Oct 17.

CNRS/MNHN/SUs - UMR 7209 AASPE, 55 rue Buffon, 75005 Paris, France.

Near Eastern Neolithic farmers introduced several species of domestic plants and animals as they dispersed into Europe. Dogs were the only domestic species present in both Europe and the Near East prior to the Neolithic. Here, we assessed whether early Near Eastern dogs possessed a unique mitochondrial lineage that differentiated them from Mesolithic European populations. Read More

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October 2018
9 Reads

A Novel Non-invasive Effective Method for Potential Treatment of Degenerative Disc Disease - A Hypothesis.

Cent Nerv Syst Agents Med Chem 2018 10 17. Epub 2018 Oct 17.

Institute of Physiologically Active Compounds Russian Academy of Sciences, Chernogolovka, 142432, Russia

The pathophysiology of the intervertebral discs plays a significant role in the people's life quality. There is not adequate research done in the pathogenesis and treatment of intervertebral disc degeneration. Alternately, self-educated physiology offers a novel and noninvasive method to reverse the degenerated discs. Read More

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October 2018
1 Read

Identification of Lynch syndrome risk variants in the Romanian population.

J Cell Mol Med 2018 Dec 16;22(12):6068-6076. Epub 2018 Oct 16.

deCODE genetics/AMGEN, Reykjavik, Iceland.

Two familial forms of colorectal cancer (CRC), Lynch syndrome (LS) and familial adenomatous polyposis (FAP), are caused by rare mutations in DNA mismatch repair genes (MLH1, MSH2, MSH6, PMS2) and the genes APC and MUTYH, respectively. No information is available on the presence of high-risk CRC mutations in the Romanian population. We performed whole-genome sequencing of 61 Romanian CRC cases with a family history of cancer and/or early onset of disease, focusing the analysis on candidate variants in the LS and FAP genes. Read More

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December 2018
4 Reads

Catch-up growth, metabolic, and cardiovascular risk in post-institutionalized Romanian adolescents.

Pediatr Res 2018 Oct 1. Epub 2018 Oct 1.

Department of Human Development and Quantitative Methodology, University of Maryland, College Park, MD, USA.

Background: Reduced prenatal growth followed by rapid postnatal weight gain are risk factors for developing metabolic and cardiovascular disease. Children reared in institutions experience a similar pattern of growth restriction followed by catch-up growth after removal. We explored whether patterns of catch-up growth affect metabolic and cardiovascular outcomes in previously institutionalized adolescents. Read More

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October 2018
7 Reads

Antioxidant/Antibacterial Electrospun Nanocoatings Applied onto PLA Films.

Materials (Basel) 2018 Oct 13;11(10). Epub 2018 Oct 13.

"P. Poni" Institute of Macromolecular Chemistry, Romanian Academy, 41A Grigore GhicaVoda Alley, 700487 Iasi, Romania.

Polylactic acid (PLA) films were coated by coaxial electrospinning with essential and vegetable oils (clove and argan oils) and encapsulated into chitosan, in order to combine the biodegradability and mechanical properties of PLA substrates with the antimicrobial and antioxidant properties of the chitosan⁻oil nanocoatings. It has been established that the morphology of the electrospun nanocoatings mainly depend on the average molecular weight (MW) of chitosan. Oil beads, encapsulated into the main chitosan nanofibers, were obtained using high-MW chitosan (Chit-H). Read More

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October 2018
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Chitosan-Stabilized Ag Nanoparticles with Superior Biocompatibility and Their Synergistic Antibacterial Effect in Mixtures with Essential Oils.

Nanomaterials (Basel) 2018 Oct 13;8(10). Epub 2018 Oct 13.

National Institute for Research & Development in Chemistry and Petrochemistry ICECHIM Bucharest, 202 Spl. Independentei, Bucharest 060021, Romania.

Silver nanoparticles (AgNPs) are considered a promising alternative to the use of antibiotics in fighting multidrug-resistant pathogens. However, their use in medical application is hindered by the public concern regarding the toxicity of metallic nanoparticles. In this study, rationally designed AgNP were produced, in order to balance the antibacterial activity and toxicity. Read More

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October 2018

The subspecific structure of Dorcadion (Cribridorcadion) pusillum Küster (Coleoptera: Cerambycidae) with description of two new subspecies from Romania.

Zootaxa 2018 Jun 29;4442(1):43-62. Epub 2018 Jun 29.

Faculty of Biology, "Al. I. Cuza" University, Bd. Carol I, Nr. 11, 700506, Iaşi, Romania..

The subspecific structure of Dorcadion pusillum Küster is revised and its distribution summarized based on published records and specimens from different collections. The taxonomic status of D. pusillum berladense Pic is reconsidered, the availability of the name "berladense" discussed in accordance with Article 45. Read More

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Water striders (Heteroptera: Gerromorpha: Gerridae) of Romania with an update on the distribution of Gerris gibbifer and G. maculatus in southeastern Europe.

Zootaxa 2018 Jun 13;4433(3):491-519. Epub 2018 Jun 13.

Department of Taxonomy & Ecology, Faculty of Biology & Geology, Babeş-Bolyai University, RO-400015, 5-7 Clinicilor Street, Cluj-Napoca, Romania..

The Romanian fauna comprises two species of Aquarius Schellenberg, 1800, eight species of Gerris Fabricius, 1794 and one species of Limnoporus Stål, 1868, and we hereby update the distribution and provide insights on the phenology and ecology of all eleven species in this country. We furthermore update the distribution of the two closely related species Gerris gibbifer Schummel, 1832 and G. maculatus Tamanini, 1946 in southeastern Europe. Read More

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June 2018
1 Read