12,070 results match your criteria Rocky Mountain Spotted Fever


Meningococcemia Masquerading as a Nonspecific Flu-Like Syndrome.

Case Rep Crit Care 2018 5;2018:2097824. Epub 2018 Nov 5.

Sky Ridge Medical Center, 10099 RidgeGate Parkway, Lone Tree, CO 80124, USA.

is a cause of bacterial meningitis and meningococcemia worldwide. Rarely, it causes invasive disease with significant lifelong sequela if survived. Early clinical recognition is key as meningococcemia is an easily treatable disease, yet mortality is 50% if it is left untreated. Read More

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November 2018
1 Read

Short-term, low-level nitrogen deposition dampens a trophic cascade between bears and plants.

Authors:
Joshua B Grinath

Ecol Evol 2018 Nov 25;8(22):11213-11223. Epub 2018 Oct 25.

Department of Biology Middle Tennessee State University Murfreesboro Tennessee.

Human activities have substantially increased atmospheric nitrogen (N) deposition in ecosystems worldwide, often leading to higher plant quality for herbivores and greater herbivory. Predators frequently suppress herbivores and indirectly benefit plants via "trophic cascades", and the strength of these interactions can also depend on N availability. However, the evidence for N deposition effects on cascades primarily comes from studies of high-level N deposition. Read More

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November 2018

Hidden cost of disease in a free-ranging ungulate: brucellosis reduces mid-winter pregnancy in elk.

Ecol Evol 2018 Nov 28;8(22):10733-10742. Epub 2018 Oct 28.

Department of Wildland Resources Utah State University Logan Utah.

Demonstrating disease impacts on the vital rates of free-ranging mammalian hosts typically requires intensive, long-term study. Evidence for chronic pathogens affecting reproduction but not survival is rare, but has the potential for wide-ranging effects. Accurately quantifying disease-associated reductions in fecundity is important for advancing theory, generating accurate predictive models, and achieving effective management. Read More

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November 2018

Migratory connectivity in the Loggerhead Shrike ().

Ecol Evol 2018 Nov 24;8(22):10662-10672. Epub 2018 Oct 24.

Department of Biology Queen's University Kingston Ontario.

Aim: We combine genetic and stable isotope data to quantify migration patterns in Loggerhead Shrike (), a species of conservation concern in North America, to assess how connectivity differs and impacts population evolution, ecology, and conservation.

Location: We sampled shrikes across the majority of their nonbreeding range, from the Atlantic Coast to the western United States east of the Rocky Mountains and throughout Mexico.

Methods: Our study used a Bayesian framework using δH from a breeding season origin feather and nuclear genetic microsatellite markers to distinguish between co-occurring migratory and nonmigratory individuals on the wintering grounds and, for migrants, to assign individuals to a breeding ground origin and genetic group. Read More

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November 2018

Predictors of clinical success with stabilization exercise are associated with lower levels of lumbar multifidus intramuscular adipose tissue in patients with low back pain.

Disabil Rehabil 2018 Dec 3:1-7. Epub 2018 Dec 3.

a Faculty of Kinesiology , University of New Brunswick , Canada.

Purpose: Investigate the construct validity of prognostic factors purported to predict clinical success with stabilization exercise for low back pain by exploring their associations with lumbar multifidus composition.

Methods: Patients with low back pain were recruited from a hospital imaging department. The presence of fivepredictors (age <40 years, positive prone instability test, aberrant trunk flexion movements, straight leg raise range of motion >91°, spinal hypermobility) were identified by standardized physical examination. Read More

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December 2018
1 Read

The Role of Elbow Tender Point Examination in the Diagnosis of Lateral Epicondylitis.

J Occup Environ Med 2018 Nov 29. Epub 2018 Nov 29.

Rocky Mountain Center for Occupational and Environmental Health (RMCOEH) (Ms Yoon, Dr Thiese, Dr Ott, Dr Wood, Dr Hegmann); Center for Ergonomics, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin (Dr Kapellusch, Dr Foster); Department of Mechanical Engineering (Dr Merryweather), University of Utah, Salt Lake City, Utah; Allina Health Clinics, Minneapolis, Minnesota (Dr Drury).

Objective: To quantify sensitivity and specificity of the tender points and demonstrate how variability in case definition impacts prevalence of lateral epicondylitis (LE).

Methods: Baseline data analyzed from 1216 workers from the WISTAH study, a multicenter prospective cohort study of upper extremity musculoskeletal disorders. All workers completed computerized questionnaires, structured interviews, and two independent physical examinations in accordance with an established protocol. Read More

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November 2018

Reversible neurogenic dysphagia: A rare presentation of vitamin b deficiency.

eNeurologicalSci 2018 Dec 19;13:31-32. Epub 2018 Nov 19.

Hospital Medicine Section, Rocky Mountain Regional VA Medical Center, Aurora, CO 80045, United States.

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December 2018

A walking behavior generates functional overland movements in the tidepool sculpin, Oligocottus maculosus.

Zoology (Jena) 2018 Dec 22;131:20-28. Epub 2018 Oct 22.

Friday Harbor Laboratories, University of Washington, 620 University Road, Friday Harbor, WA 98250, USA; Department of Biology, Howard University, 415 College Street NW, Washington, DC 20059 USA. Electronic address:

Tidepool sculpins (Oligocottus maculosus) have been observed moving overland in the rocky intertidal, and we documented the terrestrial walking behavior that they use to accomplish this. We quantified the terrestrial movements of O. maculosus and compared them to (1) their aquatic locomotion, (2) terrestrial locomotion of closely-related subtidal species (Leptocottus armatus and Icelinus borealis), and (3) terrestrial movements of walking catfishes (Clarias spp. Read More

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December 2018

Study of the Optimum Arrangement of Spherical Particles in Containers Having Different Cross Section Shapes.

J Nanosci Nanotechnol 2019 May;19(5):2717-2722

Nanotechnology Centre, VSB - Technical University of Ostrava, 17. Listopadu 15, 708 33 Ostrava-Poruba, Czech Republic.

Fluidized bed porosity is a primary property of fluidized systems when determining the minimum floating velocity. The air flow rate in the fluidized bed (or in the fluid layer of the material) increases with diminishing bed porosity. This paper is devoted to porosity calculations for a fluidized bed consisting of spherical particles having different diameters (2, 4, 6, 8, 10 mm) and in differently shaped polygonal fluidized bed cells possessing different characteristic particle floating velocities. Read More

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Temporal clustering of extreme climate events drives a regime shift in rocky intertidal biofilms.

Ecology 2018 Dec 5. Epub 2018 Dec 5.

Department of Biology, University of Pisa, CoNISMa, Via Derna 1, Pisa, Italy.

Research on regime shifts has focused primarily on how changes in the intensity and duration of press disturbances precipitate natural systems into undesirable, alternative states. By contrast, the role of recurrent pulse perturbations, such as extreme climatic events, has been largely neglected, hindering our understanding of how historical processes regulate the onset of a regime shift. We performed field manipulations to evaluate whether combinations of extreme events of temperature and sediment deposition that differed in their degree of temporal clustering generated alternative states in rocky intertidal epilithic microphytobenthos (biofilms) on rocky shores. Read More

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December 2018

Four new species of Morchella from the Americas.

Mycologia 2018 Dec 4:1-17. Epub 2018 Dec 4.

j Mycotoxin Prevention and Applied Microbiology Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service , United States Department of Agriculture , 1815 North University Street, Peoria , Illinois 61604-3020.

Morphological and molecular phylogenetic studies of true morels (Morchella) in North America, the Dominican Republic, Venezuela, Ecuador, and Peru led to the discovery of four undescribed species of Morchella. Two new species in the Elata clade, one from the Dominican Republic, initially distinguished by the informal designation Mel-18, and a newly discovered sister species from northern Arizona, are now recognized. Mel-18 is described as a novel phylogenetically distinct species, M. Read More

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December 2018
2 Reads

Adverse Events in the Efficacy of Crotalidae Polyvalent Immune Fab Antivenom vs Placebo in Recovery from Copperhead Snakebite Trial.

South Med J 2018 Dec;111(12):716-720

From the Division of Emergency Medicine, Washington University School of Medicine, St Louis, Missouri, the Division of Emergency Medicine, Duke University, Durham, North Carolina, the Department of Emergency Medicine, East Carolina University Brody School of Medicine, Greenville, North Carolina, the Department of Emergency Medicine, Virginia Commonwealth University, Richmond, the Department of Emergency Medicine, Baylor College of Medicine, Houston, Texas, the Department of Emergency Medicine, University of North Carolina, Chapel Hill, North Carolina, Texas A&M Health Sciences Center, Bryan, Rocky Mountain Poison & Drug Center, Denver, Colorado, the Department of Emergency Medicine, UT Southwestern Medical Center, Dallas, Texas, the Department of Emergency Medicine, Augusta University, Augusta, Georgia, the Department of Emergency Medicine, University of Virginia, Charlottesville, the Department of Surgery, East Carolina University Brody School of Medicine, Greenville, North Carolina, and the Department of Surgery, Marshall University, Huntington, West Virginia.

Objective: To compare the incidence of hypersensitivity reactions following copperhead envenomation treated with Fab antivenom (FabAV) or placebo.

Methods: Patients with copperhead snakebites received treatment and follow-up in a prospective, randomized, double-blind, placebo-controlled trial of FabAV or placebo. The treatment allocation ratio was 2:1 (FabAV:placebo). Read More

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December 2018
1 Read

Energetics of male field-sport athletes during the 3-min all-out test for linear and shuttle-based running.

Eur J Appl Physiol 2018 Dec 3. Epub 2018 Dec 3.

Rocky Mountain University of Health Professions, Provo, UT, USA.

Purpose: All-out, non-steady state running makes for difficult comparisons regarding linear and shuttle running; yet such differences remain an important distinction for field-based sports. The purpose of the study was to determine whether an energetic approach could be used to differentiate all-out linear from shuttle running.

Methods: Fifteen male field-sport athletes volunteered for the study (means ± SD): age, 21. Read More

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December 2018

Military-Related Exposures, Social Determinants of Health, and Dysbiosis: The United States-Veteran Microbiome Project (US-VMP).

Front Cell Infect Microbiol 2018 19;8:400. Epub 2018 Nov 19.

Rocky Mountain Mental Illness Research Education and Clinical Center, Rocky Mountain Regional VA Medical Center (MIRECC), Aurora, CO, United States.

Significant effort has been put forth to increase understanding regarding the role of the human microbiome in health- and disease-related processes. In turn, the United States (US) Veteran Microbiome Project (US-VMP) was conceptualized as a means by which to serially collect microbiome and health-related data from those seeking care within the Veterans Health Administration (VHA). In this manuscript, exposures related to military experiences, as well as conditions and health-related factors among patients seen in VHA clinical settings are discussed in relation to common psychological and physical outcomes. Read More

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November 2018
4 Reads

The rocky road to biomolecules.

Authors:
John A Baross

Nature 2018 12;564(7734):42-43

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December 2018

SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain.

Sci Rep 2018 Dec 3;8(1):17547. Epub 2018 Dec 3.

Department of Medicine, Rocky Mountain Regional VA Medical Center, Aurora, CO, USA.

SIRT3, the primary mitochondrial deacetylase, plays a significant role in enhancing the function of mitochondrial proteins. Downregulation of SIRT3 is a key component of metabolic syndrome, a precondition for obesity, diabetes and cardiovascular diseases. In this study, we examined the effects of brain mitochondrial protein hyperacetylation in western diet-fed Sirt3 mice, a model for metabolic syndrome. Read More

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December 2018
1 Read

Reproductive Endocrinology of Non-Alcoholic Fatty Liver Disease.

Endocr Rev 2018 Nov 30. Epub 2018 Nov 30.

ANZAC Research Institute, University of Sydney, Concord Hospital, Sydney NSW, Australia.

The liver and the reproductive system interact in a multifaceted bidirectional fashion. Sex steroid signaling influences hepatic endobiotic and xenobiotic metabolism and contributes to the pathogenesis of functional and structural disorders of the liver. In turn, liver function impacts on the reproductive axis via modulating sex steroid metabolism and transport to tissues via sex hormone binding globulin (SHBG). Read More

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November 2018

Biogeographical zonation of rocky intertidal communities along the coast of Peru (3.5-13.5° S Southeast Pacific).

PLoS One 2018 30;13(11):e0208244. Epub 2018 Nov 30.

Laboratorio de Ciencias del Mar, Universidad Peruana Cayetano Heredia, Lima, Perú.

The biogeography of the Peruvian Eastern Pacific coast has been described based on oceanographic parameters and qualitative species occurrence data. This has generated disagreement about the limits and existence of different biogeographic units. In this study, the distribution of rocky-shore macrobenthic communities were recorded over 41 sites along the Peruvian coastline (3. Read More

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November 2018

The Evolving Art and Science of American College of Rheumatology Guidelines.

Arthritis Rheumatol 2018 Nov 30. Epub 2018 Nov 30.

Department of Veterans Affairs and University of California San Francisco, San Francisco, California.

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November 2018
1 Read

Leon Max Lederman (1922-2018).

Authors:
Rocky Kolb

Science 2018 Nov;362(6418):1001

Department of Astronomy and Astrophysics, The University of Chicago, Chicago, IL, USA.

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November 2018

Tardigrade indexing approach on exoplanets.

Life Sci Space Res (Amst) 2018 Nov 8;19:13-16. Epub 2018 Aug 8.

Department of Animal Taxonomy and Ecology, Faculty of Biology, Adam Mickiewicz University, Poznań, Umultowska 89, Poznań 61-614, Poland. Electronic address:

Finding life on other worlds is a fascinating area of astrobiology and planetary sciences. Presently, over 3800 exoplanets, representing a very wide range of physical and chemical environments, are known. Scientists are not only looking for traces of life outside Earth, but they are also trying to find out which of Earth's known organisms (ex: tardigrades (water bears)) would be able to survive on other planets. Read More

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November 2018

DksA controls the response of the Lyme disease spirochete to starvation.

J Bacteriol 2018 Nov 26. Epub 2018 Nov 26.

Department of Medical Microbiology and Immunology, Creighton University, Omaha, NE, United States.

The pathogenic spirochete senses and responds to changes in the environment, including changes in nutrient availability, throughout its enzootic cycle in ticks and vertebrate hosts. This study examined the role of DnaK suppressor protein (DksA) in the transcriptional response of to starvation. Wild-type and mutant strains were subjected to starvation by shifting cultures grown in rich complete medium, BSK II, to a defined mammalian tissue culture medium, RPMI 1640, for 6 h under microaerobic conditions (5% CO, 3% O). Read More

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November 2018
3 Reads

Development of a rapid and visual detection method for Rickettsia rickettsii combining recombinase polymerase assay with lateral flow test.

PLoS One 2018 26;13(11):e0207811. Epub 2018 Nov 26.

Huadong Research Institute for Medicine and Biotechniques, Nanjing, Jiangsu, China.

Objectives: Rickettsia rickettsii is the causative agent of Rocky Mountain spotted fever, which is the most severe spotted fever group (SFG) rickettsiosis. Developing a simple and reliable detection method is required.

Methods: A detection method for R. Read More

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November 2018
8 Reads

Assessing the Reliability of the CAMS Rating Scale Using a Generalizability Study.

Crisis 2018 Nov 26:1-7. Epub 2018 Nov 26.

5 Department of Psychology, Catholic University of America, Washington DC, USA.

Background: An important consideration when conducting randomized controlled trials is treatment differentiation. Direct observation helps ensure that providers in different treatment groups are delivering distinct interventions. One direct observation method is the use of a measure to rate clinician performance when delivering an intervention. Read More

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November 2018
1 Read

Impact of chronic lead exposure on liver and kidney function and hematologic parameters.

Basic Clin Pharmacol Toxicol 2018 Nov 24. Epub 2018 Nov 24.

Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran.

Background: Lead, one of the most widely used metals because of its beneficial physical properties, has been reported to adversely influence several different organs and organ systems. The aim of the present study was to examine the effect of lead exposure on liver and renal function and haematologic parameters METHODS: This was a case-cohort study comparing adults with occupational, environmental or opium-related lead exposure with blood lead levels [BLL] >10μg/dl (High blood lead level (HBLL) group and age- and gender-matched normal healthy subjects (Low blood lead level [LBLL] group with BLL<10μg/dl). The complete blood count and concentrations of serum creatinine, urea, aspartate aminotransferase (AST), alanine aminotransferase (ALT) were recorded for subsequent investigation. Read More

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November 2018

Is sleep position associated with glenohumeral shoulder pain and rotator cuff tendinopathy: a cross-sectional study.

BMC Musculoskelet Disord 2018 Nov 23;19(1):408. Epub 2018 Nov 23.

Department of Occupational Science and Technology, University of Wisconsin-Milwaukee, 161 W Wisconsin Ave, Suite 6000, Milwaukee, WI, 53203-2602, USA.

Background: Glenohumeral pain and rotator cuff tendinopathy (RCT) are common musculoskeletal complaints with high prevalence among working populations. The primary proposed pathophysiologic mechanisms are sub-acromial RC tendon impingement and reduced tendon blood flow. Some sleep postures may increase subacromial pressure, potentially contributing to these postulated mechanisms. Read More

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November 2018
6 Reads

Interactions between whole-body heating and citalopram on body temperature, antidepressant-like behaviour, and neurochemistry in adolescent male rats.

Behav Brain Res 2018 Nov 20;359:428-439. Epub 2018 Nov 20.

Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO 80309, USA; Center for Neuroscience, University of Colorado Boulder, Boulder, CO 80309, USA; Department of Physical Medicine and Rehabilitation and Center for Neuroscience, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA; Veterans Health Administration, Rocky Mountain Mental Illness Research Education and Clinical Center, Denver Veterans Affairs Medical Center (VAMC), Denver, CO 80220, USA; Military and Veteran Microbiome Consortium for Research and Education (MVM-CoRE), Denver, CO 80220, USA. Electronic address:

Evidence suggests that affective disorders are associated with altered thermoregulation, and it has been hypothesized that therapeutic strategies targeting body-to-brain thermosensory systems may be effective for treating depression. Consistent with this hypothesis, a recent randomized, double blind, placebo-controlled clinical trial has suggested that infrared whole-body hyperthermia has therapeutic potential for the treatment of depression. Preclinical models may help uncover the mechanism(s) underlying the antidepressant-like effects of whole-body heating. Read More

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November 2018
1 Read

The experience of providing hospice care concurrent with cancer treatment in the VA.

Support Care Cancer 2018 Nov 22. Epub 2018 Nov 22.

Rocky Mountain Regional Veterans Affairs Medical Center, Denver-Seattle Center of Innovation, Aurora, CO, USA.

Purpose: Veterans with advanced cancer can receive hospice care concurrently with treatments such as radiation and chemotherapy. However, variations exist in concurrent care use across Veterans Affairs (VA) medical centers (VAMCs), and overall, concurrent care use is relatively rare. In this qualitative study, we aimed to identify, describe, and explain factors that influence the provision of concurrent cancer care (defined as chemotherapy or radiation treatments provided with hospice) for veterans with terminal cancer. Read More

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November 2018
4 Reads

First reported case of thrombocytopenia from a Heterodon nasicus envenomation.

Toxicon 2018 Nov 19;157:12-17. Epub 2018 Nov 19.

Rocky Mountain Poison and Drug Center - Denver Health and Hospital Authority, Denver, CO, USA.

Context: The vast majority of the 2.5 million annual worldwide venomous snakebites are attributed to Viperidae or Elapidae envenomations. Of the nearly 2000 Colubridae species described, only a handful are known to cause medically significant envenomations. Read More

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November 2018

Metal concentrations in waters, sediments and biota of the far south-east coast of New South Wales, Australia, with an emphasis on Sn, Cu and Zn used as marine antifoulant agents.

Environ Geochem Health 2018 Nov 21. Epub 2018 Nov 21.

Ecochemistry Laboratory, Institute for Applied Ecology, University of Canberra, Bruce, ACT, 2601, Australia.

Tin, Cu, Zn, Cd, Pb, Ag and Hg concentrations were measured in waters, sediments and three ubiquitous sedentary molluscs: the oyster, Saccostrea glomerata, a rocky intertidal gastropod, Austrocochlea porcata, and a sediment-dwelling gastropod, Batillaria australis, at 12 locations along the far south coast of NSW, Australia, from Batemans Bay to Twofold Bay during 2009. Metal concentrations in water for Sn, Cd, Ag and Hg were below detection limits (< 0.005 μg/L). Read More

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November 2018

Two recombinant human monoclonal antibodies that protect against lethal Andes hantavirus infection in vivo.

Sci Transl Med 2018 Nov;10(468)

Faculty of Biological Science, Department of Microbiology, Center of Biotechnology, Universidad de Concepción, 4070386 Concepción, Chile.

Andes hantavirus (ANDV) is an etiologic agent of hantavirus cardiopulmonary syndrome (HCPS), a severe disease characterized by fever, headache, and gastrointestinal symptoms that may progress to hypotension, pulmonary failure, and cardiac shock that results in a 25 to 40% case-fatality rate. Currently, there is no specific treatment or vaccine; however, several studies have shown that the generation of neutralizing antibody (Ab) responses strongly correlates with survival from HCPS in humans. In this study, we screened 27 ANDV convalescent HCPS patient sera for their capacity to bind and neutralize ANDV in vitro. Read More

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November 2018
5 Reads

Migration corridors of adult Golden Eagles originating in northwestern North America.

PLoS One 2018 21;13(11):e0205204. Epub 2018 Nov 21.

Alaska Department of Fish and Game, Fairbanks, AK, United States of America.

There has been increasing concern for Golden Eagle (Aquila chrysaetos) populations in North America due to current and future projections of mortality risk and habitat loss from anthropogenic sources. Identification of high-use movement corridors and bottlenecks for the migratory portion of the eagle population in western North America is an important first step to help habitat conservation and management efforts to reduce the risk of eagle mortality. We used dynamic Brownian Bridge movement models to estimate utilization distributions of adult eagles migrating across the western North America and identified high-use areas by calculating the overlap of individuals on population and regional levels. Read More

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November 2018

Aerosol exposure to intermediate size Nipah virus particles induces neurological disease in African green monkeys.

PLoS Negl Trop Dis 2018 Nov 21;12(11):e0006978. Epub 2018 Nov 21.

NIAID Integrated Research Facility, Ft. Detrick, Frederick, MD, United States of America.

Nipah virus (NiV) infection can lead to severe respiratory or neurological disease in humans. Transmission of NiV has been shown to occur through contact with virus contaminated fomites or consumption of contaminated food. Previous results using the African green monkey (AGM) model of NiV infection identified aspects of infection that, while similar to humans, don't fully recapitulate disease. Read More

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November 2018
5 Reads

EPCAM mutation update: Variants associated with congenital tufting enteropathy and Lynch syndrome.

Hum Mutat 2018 Nov 21. Epub 2018 Nov 21.

Department of Pediatrics, University of California, San Diego, La Jolla, California.

The epithelial cell adhesion molecule gene (EPCAM, previously known as TACSTD1 or TROP1) encodes a membrane-bound protein that is localized to the basolateral membrane of epithelial cells and is overexpressed in some tumors. Biallelic mutations in EPCAM cause congenital tufting enteropathy (CTE), which is a rare chronic diarrheal disorder presenting in infancy. Monoallelic deletions of the 3' end of EPCAM that silence the downstream gene, MSH2, cause a form of Lynch syndrome, which is a cancer predisposition syndrome associated with loss of DNA mismatch repair. Read More

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November 2018
3 Reads

Population history provides foundational knowledge for utilizing and developing native plant restoration materials.

Evol Appl 2018 Dec 24;11(10):2025-2039. Epub 2018 Sep 24.

U.S.D.A. Forest Service Rocky Mountain Research Station Boise Idaho.

A species' population structure and history are critical pieces of information that can help guide the use of available native plant materials in restoration treatments and decide what new native plant materials should be developed to meet future restoration needs. In the western United States, (bluebunch wheatgrass; Poaceae) is an important component of grassland and shrubland plant communities and commonly used for restoration due to its drought resistance and competitiveness with exotic weeds. We used next-generation sequencing data to investigate the processes that shaped 's geographic pattern of genetic variation across the Intermountain West. Read More

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December 2018
1 Read

Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients.

MBio 2018 Nov 20;9(6). Epub 2018 Nov 20.

Department of Pathology, University of California, San Diego, La Jolla, California, USA

Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common prion disease in humans and has been iatrogenically transmitted through corneal graft transplantation. Approximately 40% of sCJD patients develop visual or oculomotor symptoms and may seek ophthalmological consultation. Here we used the highly sensitive real-time quaking-induced conversion (RT-QuIC) assay to measure postmortem prion seeding activities in cornea, lens, ocular fluid, retina, choroid, sclera, optic nerve, and extraocular muscle in the largest series of sCJD patient eyes studied by any assay to date. Read More

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November 2018
4 Reads

Spatial gradient and quantitative attribution of karst soil erosion in Southwest China.

Environ Monit Assess 2018 Nov 19;190(12):730. Epub 2018 Nov 19.

Key Laboratory of Land Surface Pattern and Simulation, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, China.

Soil erosion estimation has attracted considerable attention from the scientific community and governments because of its importance to sustainable regional development. In karst areas, the heterogeneous environment and rocky desertification create difficulties in determining the influencing factors and spatial patterns of soil erosion. A quantitative analysis of karst soil erosion distribution was conducted by applying the revised soil loss equation model and the geographical detector method of attribution identification, which was based on spatial variance analysis. Read More

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November 2018
4 Reads

Global trait-environment relationships of plant communities.

Authors:
Helge Bruelheide Jürgen Dengler Oliver Purschke Jonathan Lenoir Borja Jiménez-Alfaro Stephan M Hennekens Zoltán Botta-Dukát Milan Chytrý Richard Field Florian Jansen Jens Kattge Valério D Pillar Franziska Schrodt Miguel D Mahecha Robert K Peet Brody Sandel Peter van Bodegom Jan Altman Esteban Alvarez-Dávila Mohammed A S Arfin Khan Fabio Attorre Isabelle Aubin Christopher Baraloto Jorcely G Barroso Marijn Bauters Erwin Bergmeier Idoia Biurrun Anne D Bjorkman Benjamin Blonder Andraž Čarni Luis Cayuela Tomáš Černý J Hans C Cornelissen Dylan Craven Matteo Dainese Géraldine Derroire Michele De Sanctis Sandra Díaz Jiří Doležal William Farfan-Rios Ted R Feldpausch Nicole J Fenton Eric Garnier Greg R Guerin Alvaro G Gutiérrez Sylvia Haider Tarek Hattab Greg Henry Bruno Hérault Pedro Higuchi Norbert Hölzel Jürgen Homeier Anke Jentsch Norbert Jürgens Zygmunt Kącki Dirk N Karger Michael Kessler Michael Kleyer Ilona Knollová Andrey Y Korolyuk Ingolf Kühn Daniel C Laughlin Frederic Lens Jacqueline Loos Frédérique Louault Mariyana I Lyubenova Yadvinder Malhi Corrado Marcenò Maurizio Mencuccini Jonas V Müller Jérôme Munzinger Isla H Myers-Smith David A Neill Ülo Niinemets Kate H Orwin Wim A Ozinga Josep Penuelas Aaron Pérez-Haase Petr Petřík Oliver L Phillips Meelis Pärtel Peter B Reich Christine Römermann Arthur V Rodrigues Francesco Maria Sabatini Jordi Sardans Marco Schmidt Gunnar Seidler Javier Eduardo Silva Espejo Marcos Silveira Anita Smyth Maria Sporbert Jens-Christian Svenning Zhiyao Tang Raquel Thomas Ioannis Tsiripidis Kiril Vassilev Cyrille Violle Risto Virtanen Evan Weiher Erik Welk Karsten Wesche Marten Winter Christian Wirth Ute Jandt

Nat Ecol Evol 2018 Dec 19;2(12):1906-1917. Epub 2018 Nov 19.

Institute of Biology/Geobotany and Botanical Garden, Martin Luther University Halle-Wittenberg, Halle, Germany.

Plant functional traits directly affect ecosystem functions. At the species level, trait combinations depend on trade-offs representing different ecological strategies, but at the community level trait combinations are expected to be decoupled from these trade-offs because different strategies can facilitate co-existence within communities. A key question is to what extent community-level trait composition is globally filtered and how well it is related to global versus local environmental drivers. Read More

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December 2018
15 Reads

Phytochemical characterization of bioactive compounds composition of Rosmarinus eriocalyx by RP-HPLC-ESI-QTOF-MS.

Nat Prod Res 2018 Nov 20:1-7. Epub 2018 Nov 20.

b Department of Analytical Chemistry, Faculty of Sciences , University of Granada , Granada , Spain.

Rosmarinus eriocalyx (rosemary or Elyazir) is an endemic species growing in arid steppe and rocky mountain in the South-West Algeria. This plant is well known in Algeria and Morocco due to its medicinal properties. However, little is known about its phytochemical composition. Read More

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November 2018
2 Reads

Grading of Complications After Cervical Deformity-corrective Surgery: Are Existing Classification Systems Applicable?

Clin Spine Surg 2018 Nov 16. Epub 2018 Nov 16.

Department of Orthopaedic Surgery, University of California, Davis, Davis, CA.

Study Design: This is a retrospective review of prospective multicenter cervical deformity (CD) database.

Objective: Assess the impact of complication type and Clavien complication (Cc) grade on clinical outcomes of surgical CD patients BACKGROUND:: Validated for general surgery, the Clavien-Dindo complication classification system allows for broad comparison of postoperative complications; however, the applicability of this system is unclear in CD-specific populations.

Methods: Surgical CD patients above 18 years with baseline and postoperative clinical data were included. Read More

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November 2018
4 Reads

Behavioural plasticity modulates temperature-related constraints on foraging time for a montane mammal.

J Anim Ecol 2018 Nov 17. Epub 2018 Nov 17.

U.S. Geological Survey Wyoming Cooperative Fish and Wildlife Research Unit, Department of Zoology and Physiology and Program in Ecology, University of Wyoming, 1000 E University Ave, Laramie, WY, U.S.A.

1.Contemporary climate change is altering temperature profiles across the globe. Increasing temperatures can reduce the amount of time during which conditions are suitable for animals to engage in essential activities, such as securing food. Read More

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November 2018
1 Read

Staphylococcus Aureus and Polymicrobial Skin and Soft Tissue Infections.

Am J Med Sci 2018 Dec 2;356(6):503-504. Epub 2018 Oct 2.

Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana.

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December 2018
1 Read

Temperature and pCO jointly affect the emergence and survival of cercariae from a snail host: implications for future parasitic infections in the Humboldt Current system.

Int J Parasitol 2018 Nov 15. Epub 2018 Nov 15.

Instituto de Ciencias Naturales "Alexander von Humboldt", Facultad de Ciencias del Mar y Recursos Biológicos, Universidad de Antofagasta, Av. Angamos 601, P.O. Box 170, Antofagasta, Chile.

Ocean warming and acidification are general consequences of rising atmospheric CO concentrations. In addition to future predictions, highly productive systems such as the Humboldt Current System are characterized by important variations in both temperature and pCO level, but how these physical-chemical ocean changes might influence the transmission and survival of parasites has not been assessed. This study experimentally evaluated the effects of temperature (14, 18 and 25 °C) and the combined effects of temperature (∼15 and 20 °C) and pCO level (∼500 and 1400 microatmospheres (µatm) on the emergence and survival of two species of marine trematodes-Echinostomatidae gen. Read More

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November 2018
2 Reads

Factors Impacting Perceived Access to Early Prenatal Care among Pregnant Veterans Enrolled in the Department of Veterans Affairs.

Womens Health Issues 2018 Nov 13. Epub 2018 Nov 13.

VA Connecticut Healthcare System, West Haven, Connecticut; Department of General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.

Background: Despite the relatively recent Department of Veterans Affairs (VA) policy advances in providing care for veterans and their infants during the perinatal period, little information exists regarding access to prenatal care for women veterans. Currently, VA medical centers do not provide onsite pregnancy care for veterans, but pay for care from community obstetricians through the Veterans Choice Program (VCP) and related non-VA care programs. The VCP is subcontracted to two large contractors, Health Net and TriWest, to assist the VA in administering the VCP. Read More

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November 2018
3 Reads

Towards a monoclonal antibody-based therapy for prevention and treatment of Staphylococcus aureus infections.

J Infect Dis 2018 Nov 15. Epub 2018 Nov 15.

Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT.

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November 2018
1 Read

Dominance hierarchy establishment in the invasive round goby, Neogobius melanostomus.

Behav Processes 2018 Nov 13;158:41-46. Epub 2018 Nov 13.

The Ohio State University, Stone Laboratory, United States; The Ohio State University, Department of Evolution, Ecology, and Organismal Biology, United States. Electronic address:

Organisms living at high densities may be forced to engage in conflict for access to resources such as food or shelter. When these resources are limited, the outcome of interactions may have important fitness implications. We investigated the behavioural interactions of the invasive Round Goby (Neogobius melanostomus) in a shelter-limited environment. Read More

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November 2018
6 Reads

Near-future forest vulnerability to drought and fire varies across the western United States.

Glob Chang Biol 2018 Nov 15. Epub 2018 Nov 15.

Department of Forest, Rangeland, and Fire Sciences, University of Idaho, Moscow, Idaho.

Recent prolonged droughts and catastrophic wildfires in the western United States have raised concerns about the potential for forest mortality to impact forest structure, forest ecosystem services, and the economic vitality of communities in the coming decades. We used the Community Land Model (CLM) to determine forest vulnerability to mortality from drought and fire by the year 2049. We modified CLM to represent 13 major forest types in the western United States and ran simulations at a 4-km grid resolution, driven with climate projections from two general circulation models under one emissions scenario (RCP 8. Read More

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November 2018

Hands-Only Cardiopulmonary Resuscitation Education: A Comparison of On-Screen With Compression Feedback, Classroom, and Video Education.

Ann Emerg Med 2018 Nov 8. Epub 2018 Nov 8.

American Heart Association/American Stroke Association, Dallas, TX; Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO; Rocky Mountain Regional Center, Aurora, CO.

Study Objective: We compare 3 methods of hands-only cardiopulmonary resuscitation (CPR) education, using performance scores. A paucity of research exists on the comparative effectiveness of different types of hands-only CPR education. This study also includes a novel kiosk approach that has not previously been studied, to our knowledge. Read More

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November 2018
2 Reads