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    1540 results match your criteria Rocky Mountain Spotted Fever

    1 OF 31

    Isolation and characterization of a unique strain of Rickettsia parkeri associated with the hard tick Dermacentor parumapertus Neumann in the western United States.
    Appl Environ Microbiol 2017 Feb 17. Epub 2017 Feb 17.
    Department Biochemistry, Molecular Biology, Entomology, and Plant Pathology, Mississippi State University, Mississippi.
    In 1953, investigators at the Rocky Mountain Laboratories in Hamilton, Montana, described the isolation of a spotted fever group Rickettsia (SFGR) species from Dermacentor parumapertus collected from black-tailed jackrabbits (Lepus californicus) in northern Nevada. Several decades later, investigators characterized this SFGR by using mouse serotyping methods and determined that it represented a distinct rickettsial serotype, related closely to Rickettsia parkeri; nonetheless, the parumapertus agent was not further characterized or studied. No extant isolates of the parumapertus agent remain in any rickettsial culture collection around the world which precludes contemporary phylogenetic placement of this enigmatic SFGR. Read More

    [Fatal case of rickettsiosis in a toddler from southeastern Mexico].
    Arch Argent Pediatr 2017 02;115(1):e5-e8
    Laboratorio de Enfermedades Emergentes y Reemergentes, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi" (CIR), Universidad Autónoma de Yucatán, Mérida, Yucatán, México.
    Rocky Mountain spotted fever is a disease caused by Rickettsia rickettsii, a bacteria transmitted by infected ticks. It is characterized by fever, exanthema, arthralgias and myalgias; but sometimes its clinical presentation is non specific. Due to its similarities with other exanthematic diseases like dengue or chikungunya, Rocky Mountain spotted fever is not a first line diagnosis, even though countries like Mexico show the ecologic and socioeconomic characteristics that favor its transmission, with a 30% mortality rate among pediatric patients. Read More

    Rocky Mountain Spotted Fever.
    Workplace Health Saf 2017 Jan;65(1):48
    1 University of Alabama at Birmingham.
    The tick-borne disease Rocky Mountain spotted fever (RMSF) can have deadly outcomes unless treated appropriately, yet nonspecific flu-like symptoms complicate diagnosis. Occupational health nurses must have a high index of suspicion with symptomatic workers and recognize that recent recreational or occupational activities with potential tick exposure may suggest RMSF. Read More

    Proteolytic Cleavage of the Immunodominant Outer Membrane Protein rOmpA in Rickettsia rickettsii.
    J Bacteriol 2016 Dec 28. Epub 2016 Dec 28.
    Host-Parasite Interactions Section, Laboratory of Bacteriology, Rocky Mountains Labs, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840
    Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever, contains two immunodominant proteins, rOmpA and rOmpB, in the outer membrane. Both rOmpA and rOmpB are conserved throughout spotted fever group rickettsiae as members of a family of autotransporter proteins. Previously, it was demonstrated that rOmpB is proteolytically processed with the cleavage site residing near the autotransporter domain at the carboxy-terminal end of the protein, cleaving the 168 kDa precursor into apparent 120 kDa and 32 kDa fragments. Read More

    Retrospective Study of Rocky Mountain Spotted Fever in Children.
    Pediatr Dermatol 2016 Dec 19. Epub 2016 Dec 19.
    Department of Dermatology, School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
    Background/objectives: Rocky Mountain spotted fever (RMSF), a lethal tick-borne illness, is prevalent in the south central United States. Children younger than 10 years old have the greatest risk of fatal outcome from RMSF. The objective of the current study was to review pediatric cases of RMSF seen in the dermatology consult service and to evaluate dermatology's role in the diagnosis and management of this disease. Read More

    Emerging Vector-Borne Diseases.
    Am Fam Physician 2016 Oct;94(7):551-557
    Joan C. Edwards School of Medicine at Marshall University, Huntington, WV, USA.
    Several mosquito-borne viral infections have recently emerged in North America; West Nile virus is the most common in the United States. Although West Nile virus generally causes a self-limited, flulike febrile illness, a serious neuroinvasive form may occur. Dengue is the most common vector-borne viral disease worldwide, and it has been a significant public health threat in the United States since 2009. Read More

    Notes from the Field: Community-Based Prevention of Rocky Mountain Spotted Fever - Sonora, Mexico, 2016.
    MMWR Morb Mortal Wkly Rep 2016 Nov 25;65(46):1302-1303. Epub 2016 Nov 25.
    Rocky Mountain spotted fever (RMSF), a life-threatening tickborne zoonosis caused by Rickettsia rickettsii, is a reemerging disease in Mexico (1,2). R. rickettsii is an intracellular bacterium that infects vascular endothelium and can cause multisystem organ failure and death in the absence of timely administration of a tetracycline-class antibiotic, typically doxycycline. Read More

    [Complications and cause of death in mexican children with rocky mountain spotted fever].
    Gac Med Mex 2016 Nov - Dec;152(6):789-795
    Servicio de Anatomía Patológica, Hospital Infantil del Estado de Sonora, Hermosillo, Son., México.
    Background: Rocky Mountain spotted fever is a life threatening disease caused by Rickettsia rickettsia, characterized by multisystem involvement.

    Methods: We studied 19 dead children with Rocky Mountain spotted fever. All children who were suspected of having rickettsial infections were defined as having Rocky Mountain spotted fever by serology test and clinical features. Read More

    Efficacy of Tagetes minuta (Asteraceae) essential oil against Rhipicephalus sanguineus (Acari: Ixodidae) on infested dogs and in vitro.
    Exp Appl Acarol 2016 Dec 4;70(4):483-489. Epub 2016 Nov 4.
    Empresa Brasileira de Pesquisa Agropecuária, Embrapa Gado de Corte, Avenida Rádio Maia, 830, Campo Grande, MS, CEP 79106-550, Brazil.
    Ticks from Rhipicephalus sanguineus complex are widely distributed in the world and one species from this complex is the most common tick on dogs in Brazil, notably in urban areas. This tick is a vector of several diseases. Among others it transmits the agent of canine Ehrlichiosis, a major dog infectious disease and the agent of Rocky Mountain spotted fever. Read More

    A fatal case of Brazilian spotted fever in a non-endemic area in Brazil: the importance of having health professionals who understand the disease and its areas of transmission.
    Rev Soc Bras Med Trop 2016 Sep-Oct;49(5):653-655
    Hospital das Clínicas, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.
    Brazilian spotted fever (BSF) is caused by the bacterium Rickettsia rickettsii. Because of its high case-fatality rate and apparent increase in areas of transmission, it is considered to be the rickettsial illness of primary public health interest. Cases of this disease have historically occurred in Southeastern Brazil. Read More

    Geographic eponyms: A history of geography in medicine.
    Natl Med J India 2016 May-Jun;29(3):166-168
    Department of Pathology, Columbia Asia Referral Hospital, Malleswaram, Bengaluru, Karnataka, India.
    Geographic eponyms have commonly been used in medical terminology, with diseases and medical entities being named after the place where the condition was discovered (e.g. Bombay Blood group) or invented (Jaipur Foot) or where the disease was first detected (Rocky Mountain Spotted fever) or where a consensus meeting has been held (Banff) or for other reasons (Argentina flag, Congo red stain). Read More

    Ocular manifestations of tick-borne diseases.
    Surv Ophthalmol 2016 Nov - Dec;61(6):726-744. Epub 2016 Apr 7.
    Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA. Electronic address:
    Tick-borne illnesses are a significant disease burden worldwide. Diagnosis is challenging and requires a high level of clinical suspicion. Ocular manifestations reported in association with tick-borne disease are mostly as case reports and small case series because of the relative infrequency with which they occur; however, given the global nature of health care and increase in travel in the 21st century, it is important for ophthalmologists to be aware of ocular manifestations of these diseases because early diagnosis may reduce morbidity and mortality. Read More

    Vectorial competence of Amblyomma tonelliae to transmit Rickettsia rickettsii.
    Med Vet Entomol 2016 Dec 28;30(4):410-415. Epub 2016 Sep 28.
    Estación Experimental Agropecuaria Rafaela, Instituto Nacional de Tecnología Agropecuaria, Consejo Nacional de Investigaciones Científicas y Técnicas, Rafaela, Argentina.
    The aim of this work was to test the vectorial competence of Amblyomma tonelliae (Ixodida: Ixodidae) to transmit Rickettsia rickettsii (Rickettsiales: Rickettsiaceae), the agent of Rocky Mountain spotted fever (RMSF). All parasitic stages of A. tonelliae were exposed to R. Read More

    The eye and tick-borne disease in the United States.
    Curr Opin Ophthalmol 2016 Nov;27(6):530-537
    aMayo Medical School bDepartment of Ophthalmology cMayo Clinic, Rochester, Minnesota, USA.
    Purpose Of Review: Tick-borne diseases are increasing in incidence and geographic distribution. Several diseases endemic to the United States have ophthalmic manifestations, including the most common tick-borne disease, Lyme borreliosis. As ocular complaints may lead a patient to seek medical evaluation, it is important to be aware of the systemic and ophthalmic manifestations of tick-borne diseases in order to make the correct diagnosis. Read More

    Climate change and the epidemiology of selected tick-borne and mosquito-borne diseases: update from the International Society of Dermatology Climate Change Task Force.
    Int J Dermatol 2017 Mar 1;56(3):252-259. Epub 2016 Oct 1.
    Division of Clinical Dermatology, Mayo Clinic, Rochester, MN, USA.
    Climate change refers to variation in the climate of a specific region or globally over time. A change has been reported in the epidemiology of tick- and mosquito-borne diseases in recent decades. Investigators have postulated that this effect may be associated with climate change. Read More

    Experimental infection of horses with Rickettsia rickettsii.
    Parasit Vectors 2016 Sep 13;9:499. Epub 2016 Sep 13.
    Faculty of Veterinary Medicine, University of São Paulo, São Paulo, Brazil.
    Background: Rickettsia rickettsii is vectored by ticks, and some vertebrate hosts can be sources of infection to ticks during bacteremic periods. In Brazil, the main vector for R. rickettsii is the tick Amblyomma sculptum, a member of the A. Read More

    First report of "Candidatus Rickettsia amblyommii" in west coast of Mexico.
    Ticks Tick Borne Dis 2016 Oct 3;7(6):1139-1145. Epub 2016 Sep 3.
    Laboratorio de Inmunoparasitología, Unidad de Investigación en Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, Dr. Balmis 148 Col. Doctores, Delegación Cuauhtémoc, C.P. 06726 Ciudad de México, México; Centro de Medicina Tropical, Facultad de Medicina, Universidad Nacional Autónoma de México, Dr. Balmis 148 Col. Doctores, Delegación Cuauhtémoc, C.P. 06726 Ciudad de México, México.
    We report the first case of "Candidatus Rickettsia amblyommii" detected in Amblyomma mixtum ticks on humans on the west coast of Mexico. This is the most western record of "Ca. R. Read More

    [Rocky Mountain spotted fever in Mexican children: Clinical and mortality factors].
    Salud Publica Mex 2016 Jun;58(3):385-92
    Objective: Characterize clinical manifestations and predictors of mortality in children hospitalized for spotted fever.

    Materials And Methods: Cross-sectional study in 210 subjects with a diagnosis of Rocky Mountain spotted fever (RMSF) in a pediatric hospital in Sonora, from January 1st, 2004 to June 30th, 2015. Data were analyzed using descriptive statistics and multivariate logistic regression. Read More

    Cold hardiness and influences of hibernaculum conditions on overwintering survival of American dog tick larvae.
    Ticks Tick Borne Dis 2016 Oct 10;7(6):1155-1161. Epub 2016 Aug 10.
    Department of Biological Sciences, University of Cincinnati, Cincinnati, OH, 45221, United States.
    Understanding how ticks survive the multitude of stresses experienced during winter is integral to predicting population dynamics and transmission of tick-borne pathogens. The American dog tick (Dermacentor variabilis), a predominant vector of Rocky Mountain spotted fever, overwinters in any of its post-egg life stages. In this study, we characterized the cold tolerance of larval D. Read More

    Differences in Intracellular Fate of Two Spotted Fever Group Rickettsia in Macrophage-Like Cells.
    Front Cell Infect Microbiol 2016 29;6:80. Epub 2016 Jul 29.
    Vector Borne Disease Laboratories, Department of Pathobiological Sciences, LSU School of Veterinary Medicine Baton Rouge, LA, USA.
    Spotted fever group (SFG) rickettsiae are recognized as important agents of human tick-borne diseases worldwide, such as Mediterranean spotted fever (Rickettsia conorii) and Rocky Mountain spotted fever (Rickettsia rickettsii). Recent studies in several animal models have provided evidence of non-endothelial parasitism by pathogenic SFG Rickettsia species, suggesting that the interaction of rickettsiae with cells other than the endothelium may play an important role in pathogenesis of rickettsial diseases. These studies raise the hypothesis that the role of macrophages in rickettsial pathogenesis may have been underappreciated. Read More

    Notes from the Field: Outbreak of Hand, Foot, and Mouth Disease Caused by Coxsackievirus A6 Among Basic Military Trainees - Texas, 2015.
    MMWR Morb Mortal Wkly Rep 2016 Jul 8;65(26):678-80. Epub 2016 Jul 8.
    On July 7, 2015, a man aged 22 years reported to sick call during basic military training at Lackland Air Force Base (AFB), Texas. He had erythematous, crusted papulovesicular lesions on the extensor surfaces of the upper and lower extremities. The patient was afebrile and otherwise well, and was evaluated later that day by the dermatology service. Read More

    Virulence genes of Rickettsia rickettsii are differentially modulated by either temperature upshift or blood-feeding in tick midgut and salivary glands.
    Parasit Vectors 2016 06 10;9(1):331. Epub 2016 Jun 10.
    Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
    Background: Rickettsia rickettsii, the etiological agent of Rocky Mountain spotted fever, is transmitted to humans by ticks. During tick feeding, R. rickettsii is exposed to both temperature elevation and components of the blood meal, which have previously been associated with the reactivation of its virulence. Read More

    Comparative value of blood and skin samples for diagnosis of spotted fever group rickettsial infection in model animals.
    Ticks Tick Borne Dis 2016 Jul 26;7(5):1029-34. Epub 2016 May 26.
    Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, GA, United States.
    The definitive diagnosis of spotted fever group (SFG) rickettsioses in humans is challenging due to the retrospective nature and cross reactivity of the serological methods and the absence of reliable and consistent samples for molecular diagnostics. Existing data indicate the transient character of bacteremia in experimentally infected animals. The ability of arthropod vectors to acquire rickettsial infection from the laboratory animals in the absence of systemic infection and known tropism of rickettsial agents to endothelial cells of peripheral blood vessels underline the importance of local infection and consequently the diagnostic potential of skin samples. Read More

    A Clinical Review of Tick-Borne Diseases in Arkansas.
    J Ark Med Soc 2016 May;112(13):254-8
    Tick-borne diseases are illnesses transmitted by ticks harboring wide variety of pathogens. Arkansas is reported as one of the states with a high incidence of tick-borne diseases. In Arkansas the four most frequently occurring tick-borne diseases are Rocky Mountain Spotted Fever (RMSF, also known as Spotted Fever Rickettsiosis), Ehrlichiosis, Tularemia and Anaplasmosis. Read More

    Molecular Ecological Insights into Neotropical Bird-Tick Interactions.
    PLoS One 2016 20;11(5):e0155989. Epub 2016 May 20.
    Smithsonian Tropical Research Institute, Panama City, Republic of Panama.
    In the tropics, ticks parasitize many classes of vertebrate hosts. However, because many tropical tick species are only identifiable in the adult stage, and these adults usually parasitize mammals, most attention on the ecology of tick-host interactions has focused on mammalian hosts. In contrast, immature Neotropical ticks are often found on wild birds, yet difficulties in identifying immatures hinder studies of birds' role in tropical tick ecology and tick-borne disease transmission. Read More

    Diagnosis and Management of Tickborne Rickettsial Diseases: Rocky Mountain Spotted Fever and Other Spotted Fever Group Rickettsioses, Ehrlichioses, and Anaplasmosis - United States.
    MMWR Recomm Rep 2016 May 13;65(2):1-44. Epub 2016 May 13.
    National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, Georgia.
    Tickborne rickettsial diseases continue to cause severe illness and death in otherwise healthy adults and children, despite the availability of low-cost, effective antibacterial therapy. Recognition early in the clinical course is critical because this is the period when antibacterial therapy is most effective. Early signs and symptoms of these illnesses are nonspecific or mimic other illnesses, which can make diagnosis challenging. Read More

    High Seroprevalence for Rickettsia rickettsii in Equines Suggests Risk of Human Infection in Silent Areas for the Brazilian Spotted Fever.
    PLoS One 2016 11;11(4):e0153303. Epub 2016 Apr 11.
    Department of Public Health, State University of Campinas, São Paulo, Brazil.
    Equines play a role in the epidemiology of Brazilian spotted fever (BSF) since they are a primary host for the tick Amblyomma sculptum. We studied the seroprevalence for three species of Rickettsia in equines in four endemic (with human cases) and in four non-endemic areas (no human cases) in the Piracicaba River Basin, São Paulo, Brazil. A serological survey of 504 equines was performed: around 63 animals were sampled in each area and tested through indirect immunofluorescence assay for R. Read More

    Human Infections by Multiple Spotted Fever Group Rickettsiae in Tennessee.
    Am J Trop Med Hyg 2016 Jun 28;94(6):1212-7. Epub 2016 Mar 28.
    Vector-Borne Diseases Section, Communicable and Environmental Diseases, Tennessee Department of Health, Nashville, Tennessee; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch at Galveston, Galveston, Texas; Departments of Medicine and Health Policy, Vanderbilt University School of Medicine, Nashville, Tennessee
    Rocky Mountain spotted fever is the most common tick-borne disease in Tennessee. However, Rickettsia rickettsii has rarely been isolated from endemic ticks, suggesting rickettsioses may be caused by other species. A total of 56 human serum samples that were serologically positive for exposure to Rickettsia were obtained from commercial laboratories in 2010 and 2011. Read More

    Exposure of dogs to spotted fever group rickettsiae in urban sites associated with human rickettsioses in Costa Rica.
    Ticks Tick Borne Dis 2016 Jul 10;7(5):748-53. Epub 2016 Mar 10.
    Centro de Investigación en Enfermedades Tropicales, Universidad de Costa Rica, San José, Costa Rica; Sección de Entomología Médica, Departamento de Parasitología, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica. Electronic address:
    The zoonotic transmission cycles of Rickettsia rickettsii and other spotted fever group (SFG) rickettsiae in Latin America have usually been associated with rural or sylvatic environments, although domestic dogs can be implicated in more populated settings. In this study, exposure of dogs to SFG rickettsiae in the Greater Metropolitan Area of Costa Rica was investigated. Dogs from sites associated with human cases and from dog shelters were evaluated by indirect immunofluorescence assay (IFA) using antigen of SFG rickettsiae. Read More

    Tick-Borne Illnesses.
    Curr Sports Med Rep 2016 Mar-Apr;15(2):98-104
    Madigan Army Medical Center, Department of Family Medicine, Fort Lewis, WA.
    Tick-borne diseases are prevalent throughout the United States. These illnesses are caused by a variety of different pathogens that use ticks as vectors, including bacteria, viruses, rickettsia, and protozoa. Some of the most common illnesses caused by ticks are Lyme disease, Rocky Mountain spotted fever, babesiosis, ehrlichiosis, anaplasmosis, tularemia, Colorado tick fever, tick-borne relapsing fever, and Powassan disease. Read More

    Hierarchical Bayesian Spatio-Temporal Analysis of Climatic and Socio-Economic Determinants of Rocky Mountain Spotted Fever.
    PLoS One 2016 4;11(3):e0150180. Epub 2016 Mar 4.
    Center for Excellence in Vector Borne Diseases, Department of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, Kansas, United States of America.
    This study aims to examine the spatio-temporal dynamics of Rocky Mountain spotted fever (RMSF) prevalence in four contiguous states of Midwestern United States, and to determine the impact of environmental and socio-economic factors associated with this disease. Bayesian hierarchical models were used to quantify space and time only trends and spatio-temporal interaction effect in the case reports submitted to the state health departments in the region. Various socio-economic, environmental and climatic covariates screened a priori in a bivariate procedure were added to a main-effects Bayesian model in progressive steps to evaluate important drivers of RMSF space-time patterns in the region. Read More

    Prevalence, Distribution, and Development of an Ecological Niche Model of Dermacentor variabilis Ticks Positive for Rickettsia montanensis.
    Vector Borne Zoonotic Dis 2016 Apr 22;16(4):253-63. Epub 2016 Feb 22.
    1 Viral and Rickettsial Diseases Department, Naval Medical Research Center , Silver Spring, Maryland.
    Rickettsia montanensis has long been considered a nonpathogenic member of the spotted fever group rickettsiae. However, the infection potential of R. montanensis is being revisited in light of its recent association with a case of human infection in the United States and the possibility that additional cases may have been misdiagnosed as Rocky Mountain spotted fever. Read More

    Specifying Pathogen Associations of Amblyomma maculatum (Acari: Ixodidae) in Western Tennessee.
    J Med Entomol 2016 Mar;53(2):435-40
    Amblyomma maculatum Koch (Acari: Ixodidae) is established in western Tennessee, a region with increased risk for Rocky Mountain spotted fever and ehrlichiosis. This tick transmits Rickettsia parkeri to humans, likely contributing to cases of rickettsiosis in the region. The objective was to determine pathogen associations within questing and host-collected A. Read More

    Bacterial small RNAs in the Genus Rickettsia.
    BMC Genomics 2015 Dec 18;16:1075. Epub 2015 Dec 18.
    Department of Pathology, the University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555, USA.
    Background: Rickettsia species are obligate intracellular Gram-negative pathogenic bacteria and the etiologic agents of diseases such as Rocky Mountain spotted fever (RMSF), Mediterranean spotted fever, epidemic typhus, and murine typhus. Genome sequencing revealed that R. prowazekii has ~25 % non-coding DNA, the majority of which is thought to be either "junk DNA" or pseudogenes resulting from genomic reduction. Read More

    Rickettsia rickettsii and Rickettsia felis infection in Rhipicephalus sanguineus ticks and Ctenocephalides felis fleas co-existing in a small city in Yucatan, Mexico.
    J Vector Ecol 2015 Dec;40(2):422-4
    Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, México, Avenida Itzaés # 490 × Calle 59 Colonia Centro C.P, 97000 Mérida, Yucatán, México.

    Failure of a heterologous recombinant Sca5/OmpB protein-based vaccine to elicit effective protective immunity against Rickettsia rickettsii infections in C3H/HeN mice.
    Pathog Dis 2015 Dec 29;73(9):ftv101. Epub 2015 Oct 29.
    University of Chicago, Department of Microbiology, Chicago, IL 60637, USA Howard T. Ricketts Laboratory, Argonne, IL 60439, USA Vector-Borne Disease Laboratories, Department of Pathobiological Sciences, Louisiana State University School of Veterinary Medicine, Baton Rouge, LA 70803, USA
    Spotted fever group (SFG) rickettsial species are obligate intracellular tick-borne pathogens that are responsible for important human diseases. Previous reports have demonstrated the feasibility of using recombinant surface cell antigen Sca5/OmpB to elicit protective immunity against homologous challenges using murine models of Mediterranean spotted fever and Rocky Mountain spotted fever. In addition, the feasibility of generating cross-protective immunity against related rickettsial species has also been established, but the molecular basis for these phenomena was not explored. Read More

    Effect of Rickettsia rickettsii (Rickettsiales: Rickettsiaceae) Infection on the Biological Parameters and Survival of Its Tick Vector-Dermacentor variabilis (Acari: Ixodidae).
    J Med Entomol 2016 Jan 22;53(1):172-6. Epub 2015 Oct 22.
    Centers for Disease Control and Prevention, Rickettsial Zoonoses Branch, 1600 Clifton Rd. NE, Atlanta, GA 30329-4018 and
    Rocky Mountain spotted fever, caused by Rickettsia rickettsii, is a potentially fatal tick-borne disease spread from North America to Argentina. The major vectors of R. rickettsii in the United States are Dermacentor andersoni Stiles and Dermacentor variabilis (Say). Read More

    Subcorneal pustular dermatosis associated with Coccidioides immitis.
    Dermatol Online J 2015 Aug 15;21(8). Epub 2015 Aug 15.
    University of California, Davis.
    Coccidioidomycosis (AKA "Valley fever") is a primary pulmonary infection via airborne spores released from coccidioides immitis in the soil. Reactive cutaneous eruptions resulting from the pulmonary infection are difficult to diagnose because skin biopsies do not contain the organism. We present an adolescent male with primary pulmonary C. Read More

    Molecular Detection of Rickettsia Species Within Ticks (Acari: Ixodidae) Collected from Arkansas United States.
    J Med Entomol 2015 May 29;52(3):500-8. Epub 2015 Mar 29.
    Creative Testing Solutions, Tempe AZ 85282.
    Rocky Mountain spotted fever (RMSF), caused by the etiological agent Rickettsia rickettsii, is the most severe and frequently reported rickettsial illness in the United States, and is commonly diagnosed throughout the southeast. With the discoveries of Rickettsia parkeri and other spotted fever group rickettsiae (SFGR) in ticks, it remains inconclusive if the cases reported as RMSF are truly caused by R. rickettsii or other SFGR. Read More

    Ultrastructure of Presumed "Candidatus Rickettsia Andeanae" in Amblyomma maculatum (Acari: Ixodidae).
    J Med Entomol 2014 Nov;51(6):1317-21
    Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, 240 Wise Center Drive, Mississippi State, MS 39762, USA.
    Amblyomma maculatum Koch, 1844 (also known as the Gulf Coast tick) is found in parts of the Americas, including the central and southern United States. Its primary importance is as the vector of Rickettsia parkeri, a spotted fever group rickettsia that causes an illness similar to, but milder than, Rocky Mountain spotted fever. A second spotted fever group rickettsia, "Candidatus Rickettsia andeanae," was detected in Gulf Coast ticks approximately 10 yr ago. Read More

    Ongoing Cerebral Vasculitis During Treatment of Rocky Mountain Spotted Fever.
    Pediatr Neurol 2015 Nov 22;53(5):434-8. Epub 2015 Jul 22.
    Division of Pediatric Neurology, The Johns Hopkins University School of Medicine, Baltimore, Maryland; Kennedy Krieger Institute, Baltimore, Maryland.
    Background: Rocky Mountain spotted fever is a tickborne infection that produces a systemic small-vessel vasculitis; its prognosis is excellent if appropriate treatment is initiated early. Because the advent of effective antirickettsial therapies predates the widespread use of brain magnetic resonance imaging, there are limited data on the effect of untreated Rocky Mountain spotted fever infection on neuroimaging studies.

    Patient Description: We describe a 7-year-old girl with delayed treatment of Rocky Mountain spotted fever who suffered severe neurological impairment. Read More

    Pathogenic potential of a Costa Rican strain of 'Candidatus Rickettsia amblyommii' in guinea pigs (Cavia porcellus) and protective immunity against Rickettsia rickettsii.
    Ticks Tick Borne Dis 2015 Sep 17;6(6):805-11. Epub 2015 Jul 17.
    Centro de Investigación en Enfermedades Tropicales, Universidad de Costa Rica, San José, Costa Rica; Sección de Entomología Médica, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica. Electronic address:
    'Candidatus Rickettsia amblyommii' is a spotted fever group rickettsia that is not considered pathogenic, although there is serologic evidence of possible infection in animals and humans. The aim of this study was to evaluate the pathogenic potential of a Costa Rican strain of 'Candidatus R. amblyommii' in guinea pigs and determine its capacity to generate protective immunity against a subsequent infection with a local strain of Rickettsia rickettsii isolated from a human case. Read More

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