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Therap Adv Gastroenterol 2022 11;15:17562848211062406. Epub 2022 Feb 11.

Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Internal Medicine, Södra Älvsborg Hospital, Borås, Sweden.

Introduction: Ulcerative colitis (UC) contributes to impaired health-related quality of life (HRQoL). Although disease activity is the most important factor, reduced HRQoL has been reported even in quiescent UC. We aimed to determine HRQoL, and identify predictors thereof, in patients with long-standing UC in remission. Read More

Trauma Case Rep 2022 Feb 8;37:100578. Epub 2021 Dec 8.

Department of Surgery, Broward General Medical Center, 1600 S Andrews Ave, Fort Lauderdale, FL 33316, United States of America.

Traumatic rupture of an ovarian endometrioma is extremely rare injury. We describe a case of a 63-year-old female presenting after a motor vehicle crash (MVC) with complex abdominal injuries requiring exploratory laparotomy that was complicated by delayed presentation of an ovarian endometrioma rupture on second look laparotomy. During the repeat exploration of the abdomen, multiple regions of small bowel and the pelvic floor were noted to be covered with a brown-colored material which was concerning for fecal matter from a missed enterotomy. Read More

Urol Ann 2021 Oct-Dec;13(4):442-445. Epub 2021 Sep 2.

Department of Urology, Hospital Pengajar Universiti Putra Malaysia, Selangor Darul Ehsan, Malaysia.

Linitis plastica is a rare tumor with poor prognosis. It is a circumferentially infiltrating intramural tumor which can result in rigid, nondistensible thickening of the affected organ. It most commonly affects the stomach, followed by the rectum, and can be due to primary or secondary cancer. Read More

Dis Colon Rectum 2021 12;64(12):e728-e734

Department of Surgery and Cancer, Imperial College London, London, United Kingdom.

Background: This is an analysis of the first 50 in-human uses of a novel digital rigid sigmoidoscope. The technology provides digital image capture, telemedicine capabilities, improved ergonomics, and the ability to biopsy under pneumorectum while maintaining the low cost of conventional rigid sigmoidoscopy. The primary outcome was adverse events, and the secondary outcome was diagnostic view. Read More

Trauma Surg Acute Care Open 2021 23;6(1):e000727. Epub 2021 Jul 23.

Major Trauma, Imperial College Healthcare NHS Trust, London, UK.

Background: Penetrating gluteal injuries (PGIs) are an increasingly common presentation to major trauma centers (MTCs) in the UK and especially in London. PGIs can be associated with mortality and significant morbidity. There is a paucity of consistent guidance on how best to investigate and manage these patients. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2021 Apr;24(4):319-326

Department of Gastrointestinal Surgery, Peking University People's Hospital, Beijing 100044, China Laboratory of Surgical Oncology, Peking University People's Hospital, Beijing 100044, China Beijing Key Laboratory of Colorectal Cancer Diagnosis and Treatment Research, Peking University People's Hospital, Beijing 100044, China.

To understand the current status of diagnosis and treatment regarding the protection of defecation function in Chinese surgeons performing sphincter-preserving resections (SPR) for rectal cancer in order to discover the problems existing in the function protection during SPR and provide support and reference for the standardized clinical management of rectal cancer. A cross-sectional survey was performed. Colorectal surgeons who obtained the medical qualifications and volunteered to participate in this study were included, and respondents with incomplete information were excluded. Read More

Dis Colon Rectum 2020 09;63(9):1185-1189

Department of Surgery, St. Joseph Mercy Hospital, Ann Arbor, Michigan.

Case Summary: A 65-year-old man underwent colonoscopy to evaluate rectal bleeding and was found to have a low rectal mass. Biopsy revealed moderately differentiated microsatellite stable adenocarcinoma. The tumor was palpable at the fingertip in the anterior rectum with the inferior border 5 cm from the anal verge by rigid proctoscopy. Read More

Dis Colon Rectum 2020 12;63(12):1579-1583

Department of Abdominal and General Surgery and Oncology, National Cancer Institute, Vilnius, Lithuania.

Case Summary: An 84-year-old male patient was complaining of constipation and rectal bleeding for 6 months. Colonoscopy and rigid sigmoidoscopy showed a posterior upper rectal mass (13 cm from anus). Histopathology confirmed moderately differentiated adenocarcinoma. Read More

Abdom Radiol (NY) 2021 02 20;46(2):449-458. Epub 2020 Jul 20.

Department of Biostatistics, Korea University College of Medicine, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.

Purpose: To determine an accurate method for localizing rectal cancer using the distance from the anal verge on preoperative MRI.

Methods: This prospective study included 50 patients scheduled for MRI evaluation of rectal cancer. After rectal filling with gel, MRI was performed with two markers attached at the anal verge. Read More

Lakartidningen 2020 04 20;117. Epub 2020 Apr 20.

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We performed a retrospective observational study to investigate the diagnostic accuracy of rigid sigmoidoscopy (RS) in patients with rectal cancer (n=279). Fifty-six percent of the patients had performed an RS within three months before diagnosis and mostly by a primary care provider (93%). In 21% of the patients the physician determined that the examination was normal, in 50% a rectal tumor was suspected and in 29% of cases an unspecific pathology (e. Read More

Injury 2020 May 24;51(5):1238-1241. Epub 2020 Feb 24.

Department of Surgery, University of the Witwatersrand, Johannesburg, South Africa; Department of Surgery, University of KwaZulu Natal, Durban, South Africa. Electronic address:

Introduction: The management of rectal trauma remains controversial. There are three modalities which have been used to manage these injuries; proximal diversion (PD), washout of the distal rectum (DRW) and presacral drainage (PSD). The EAST group tentatively advocate mandatory proximal diversion for extraperitoneal rectal injuries and omitting DRW or PSD. Read More

Am Surg 2019 Nov;85(11):e541-e543

N Z Med J 2019 04 12;132(1493):38-43. Epub 2019 Apr 12.

Head of Department in General Surgery, Consultant General Surgeon, Department of General Surgery, Taranaki Base Hospital, New Plymouth.

Aim: At our institution there has been a long-standing early operative approach to large bowel volvulus as well as initial decompression with rigid sigmoidoscopy. The primary aim of this study was to investigate the safety and efficacy of this approach on reducing readmissions and complications. Secondary aims were to investigate the safety and efficacy of bedside rigid sigmoidoscopy in decompression of sigmoid volvulus and investigate the sensitivity of abdominal x-ray in the diagnosis of acute large bowel volvulus. Read More

World J Clin Cases 2018 Oct;6(12):554-558

Department of Surgery, Chonbuk National University Medical School and Hospital, Jeonju 54907, Chonbuk, South Korea.

Linitis plastica is a rare condition showing circumferentially infiltrating intramural anaplastic carcinoma in a hollow viscus, resulting in a tissue thickening of the involved organ as constricted, inelastic, and rigid. While most secondary rectal linitis plastica (RLP) is caused by metastasis from stomach, breast, gallbladder, or bladder cancer, we report an extremely rare and unique case of secondary RLP due to prostate cancer with computed tomography (CT) and magnetic resonance imaging (MRI) findings, including diffusion weighted imaging (DWI). A 78-year-old man presented with approximately a 2-mo history of constipation and without cancer history. Read More

J Int AIDS Soc 2018 10;21(10):e25199

Division of Infectious Diseases, Department of Medicine, The Hope Clinic of the Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.

Introduction: Oral pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) is highly effective in preventing HIV infection among men who have sex with men (MSM). The effects of consistent personal lubricant use in the rectum on tissue PrEP drug concentrations and the rectal microbiota are unknown. We investigated rectal PrEP drug concentrations and the microbiota in MSM before and after repeated rectal application of a hyperosmolar lubricant. Read More

Eur J Surg Oncol 2019 03 9;45(3):324-330. Epub 2018 Oct 9.

Department of Surgery, Yonsei University College of Medicine, Seoul, South Korea. Electronic address:

Introduction: In measuring tumor height for rectal cancer, rigid sigmoidoscopy (RS) is a standard modality, and the accuracy of magnetic resonance imaging(MRI) in patients with/without preoperative chemoradiotherapy (CRT) has not been fully investigated. The aim of this study was to investigate the accuracy of MRI for measuring tumor height.

Materials And Methods: Among rectal cancer patients seen between July 2006 and May 2012, the initial group (RS and MRI available at initial diagnosis) and the post-CRT group (RS and MRI available after the completion of preoperative CRT) were selected. Read More

Colorectal Dis 2018 10 14;20(10):923-930. Epub 2018 May 14.

Department of Surgery, Oncology and Gastroenterology, Third Surgical Clinic, University of Padua, Padua, Italy.

Aim: The aim of this study was to investigate risk factors for anastomotic stenosis in patients operated on for diverticular disease. Histological inflammation and diverticula at the resection margins were also considered.

Method: Patients' characteristics, the surgical technique and postoperative complications were collected from the medical records. Read More

Ir J Med Sci 2019 Feb 22;188(1):119-124. Epub 2018 Mar 22.

Department of Surgery, Trinity Centre of Learning and Development, Tallaght Hospital, Dublin 24, Ireland.

Aims: Evaluation of the role and impact of introducing a dedicated coloproctology procedure clinic in tertiary referral colorectal unit.

Methods: A retrospective analysis of 126 consecutive patients managed in the coloproctology clinic between March2015 and September 2016 was carried out. All patients were preselected for attendance based on symptom-based protocol. Read More

Clin Colon Rectal Surg 2018 Jan 19;31(1):24-29. Epub 2017 Dec 19.

Division of Colon and Rectal Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.

With increased use of explosive devices in warfare, anal trauma is often seen coupled with more complex pelviperineal injury. While the associated mortality is high, casualties that survive are often left with disabling fecal incontinence from damage to the anosphincteric complex. After resolution of the acute insult, the initial evaluation mandates a thorough physical exam, including endoscopic evaluation with rigid proctoscopy and flexible sigmoidoscopy, as well as adjunctive testing, specifically anal manometry and endoanal ultrasound. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2017 Aug;20(8):852-856

Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.

Transanal endoscopic microsurgery (TEM) is currently the only one-port system in endoscopic surgery, which a direct endoluminal approach can lead to the target organ through a natural opening of human body. TEM has been applied in colorectal surgery for over 3 decades. Compared with radical surgery, TEM has the advantages, such as quicker recovery, shorter hospital stay and fewer complications. Read More

World J Gastrointest Surg 2016 Oct;8(10):679-684

Abraham A Ayantunde, Zynep Unluer, Department of Surgery, Southend University Hospital, Westcliff-on-Sea SS0 0BY, United Kingdom.

Aim: To highlight the rising trend in hospital presentation of foreign bodies retained in the rectum over a 5-year period.

Methods: Retrospective review of the cases of retained rectal foreign bodies between 2008 and 2012 was performed. Patients' clinical data and yearly case presentation with data relating to hospital episodes were collected. Read More

Medicine (Baltimore) 2016 Sep;95(37):e4638

Department of Colorectal Surgery, Wan Fang Hospital Department of Surgery, College of Medicine Division of General Surgery, Department of Surgery Cancer Center, Taipei Medical University Hospital Graduate Institute of Cancer Biology and Drug Discovery Department of General Surgery, Wan Fang Hospital, Taipei Medical University Department of Radiation Oncology, Taipei Medical University Hospital Institute of Toxicology, College of Medicine, National Taiwan University Department of Radiation Oncology, Wan Fang Hospital Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei Department of Biotechnology, Hungkuang University, Taichung, Taiwan.

To investigate the outcomes of the selective neoadjuvant concurrent chemoradiotherapy (CCRT) in lower 3rd rectal cancer patients in different groups (with or without neoadjuvant CCRT), especially in survival rate, local recurrence rate, and sphincter preservation rate.From January 1999 to December 2012, 69 consecutive patients who had histologically proven adenocarcinoma of lower 3rd rectum, defined preoperatively as lower tumor margin within 7 cm from the anal verge as measured by rigid sigmoidoscopy, received total mesorectum excision (TME). Our inclusion criteria of neoadjuvant CCRT are lower 3rd rectal cancer, stage II/III, and large (diameter >5 cm or >1/2 of circumference). Read More

Intest Res 2016 Jul 27;14(3):285-8. Epub 2016 Jun 27.

Division of Gastroenterology, Department of Internal Medicine, Chonbuk National University College of Medicine and Hospital, Jeonju, Korea.

Endoscopic treatments have emerged as an alternative to surgery, in the treatment of benign colorectal stricture. Unlike endoscopic balloon dilatation, there is limited data on endoscopic electrocautery incision therapy for benign colorectal stricture, especially with regards to safety and long-term patency. We present a case of a 29-year-old female with Crohn's disease who had difficulty in defecation and passing thin stools. Read More

BMJ Case Rep 2016 Jun 20;2016. Epub 2016 Jun 20.

Department of Trauma Services, Hurley Medical Center, Flint, Michigan, USA.

We report a case of a 70-year-old woman who presented with progressively increasing intensity of lower abdominal, pelvic and rectal pain of 3-day duration. She had similar symptoms intermittently over the preceding 2 years. CT of the abdomen and pelvis revealed the presence of a 3. Read More

J Hosp Infect 2016 May 10;93(1):112-3. Epub 2016 Feb 10.

Brighton and Sussex University Hospitals NHS Trust, Royal Sussex County Hospital, Eastern Road, Brighton, BN2 5BE, UK.

Acta Chir Belg 2014 Nov-Dec;114(6):364-9

Department of Abdominal Surgery, University Hospital Gasthuisberg, Leuven, Belgium.

Background: Rigid proctosigmoidoscopy is recommended for measuring the height of rectal neoplasms but appears to be performed in only a minority of patients. Our aim was to compare endoscopic and radiological measurement of rectal tumour location with a focus on differentiation between mid and high rectal cancer.

Methods: Medical records of 66 rectal cancer patients were reviewed. Read More

BMC Health Serv Res 2015 Feb 1;15:51. Epub 2015 Feb 1.

Department of Family and Community Medicine, St. Michael's Hospital and University of Toronto, Toronto, ON, Canada.

Background: Because of the increased life-expectancy of persons with HIV, the need for age-appropriate colorectal cancer screening among these patients will increase. We examined rates of colorectal cancer screening among HIV-infected men aged 50 to 65 years.

Methods: We used Ontario's administrative databases to identify all men between the ages of 50 and 65 years who were alive on April 1, 2007, and identified HIV-infected men using a validated case-finding algorithm. Read More

Colorectal Dis 2013 Jul;15(7):836-41

Department of Colorectal Surgery, Queen Elizabeth Hospital, Birmingham, UK.

Aim: The diagnosis and treatment of ulcerative colitis (UC) is traditionally the realm of gastroenterologists. However, the symptoms of UC overlap with those of bowel cancer and patients may be initially referred to colorectal surgery clinics. The aims of this study were to define which specialty most frequently diagnoses UC and to determine if there were differences in management between the two specialities. Read More