Eur Thyroid J 2016 Dec 3;5(4):231-239. Epub 2016 Dec 3.
Department of Endocrinology and Diabetes, The Alfred Hospital, Monash University, Melbourne, VIC, Australia; Department of Medicine, Monash University, Melbourne, VIC, Australia.
Immunoglobulin G4-related disease (IgG4-RD) is a new disease category involving many organ systems, including the endocrine system in general and the thyroid in particular. Since an initial association was made between hypothyroidism and autoimmune (IgG4-related) pancreatitis, more forms of IgG4-related thyroid disease (IgG4-RTD) have been recognized. Four subcategories of IgG4-RTD have so far been identified: Riedel thyroiditis (RT), fibrosing variant of Hashimoto thyroiditis (FVHT), IgG4-related Hashimoto thyroiditis, and Graves disease with elevated IgG4 levels. Read More