2,424 results match your criteria Rickettsialpox


Amblyomma maculatum-associated rickettsiae in vector tissues and vertebrate hosts during tick feeding.

Exp Appl Acarol 2019 Feb 15. Epub 2019 Feb 15.

Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, 39762, USA.

Rickettsia parkeri, a causative agent of spotted fever rickettsiosis, is transmitted by Amblyomma maculatum (Gulf Coast tick), a tick that may also carry a non-pathogenic spotted fever group Rickettsia, "Candidatus Rickettsia andeanae". Here, we evaluated R. parkeri and "Candidatus R. Read More

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http://dx.doi.org/10.1007/s10493-019-00343-xDOI Listing
February 2019

Local host-tick coextinction in neotropical forest fragments.

Int J Parasitol 2019 Feb 8. Epub 2019 Feb 8.

Smithsonian Tropical Research Institute, P.O. Box 0843-03092, Panama City, Republic of Panama; Department of Environmental Sciences, Wageningen University & Research, P.O. Box 47, 6700 AA Wageningen, the Netherlands.

Ticks are obligatory parasites with complex life cycles that often depend on larger bodied vertebrates as final hosts. These traits make them particularly sensitive to local coextinction with their host. Loss of wildlife abundance and diversity should thus lead to loss of tick abundance and diversity to the point where only generalist tick species remain. Read More

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http://dx.doi.org/10.1016/j.ijpara.2018.08.008DOI Listing
February 2019

Attempt to uncover reservoirs of human spotted fever rickettsiosis on the Fleurieu Peninsula, South Australia.

J Vector Borne Dis 2018 Jul-Sep;55(3):239-241

School of Biological Sciences, University of Adelaide, Adelaide, Australia.

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http://dx.doi.org/10.4103/0972-9062.249483DOI Listing
February 2019

Spotted fever rickettsioses causing myocarditis and ARDS: a case from Sri Lanka.

BMC Infect Dis 2018 Dec 29;18(1):705. Epub 2018 Dec 29.

Department of General Medicine, General Hospital (Teaching), Kandy, Sri Lanka.

Background: Spotted fever group of rickettsial infections are emerging in Sri Lanka. We describe a patient with rapidly progressing ARDS and myocarditis secondary to spotted fever caused by Rickettsia conorii. ARDS and myocarditis are rare complications of Rickettsia conorii infections and only a few cases are reported to date. Read More

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http://dx.doi.org/10.1186/s12879-018-3631-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311067PMC
December 2018
5 Reads

High Seroprevalence Against Typhus Group and Spotted Fever Group Rickettsiae in Rural Indigenous Populations of Peninsular Malaysia.

Vector Borne Zoonotic Dis 2018 Dec 12. Epub 2018 Dec 12.

2 Department of Parasitology and Faculty of Medicine, University of Malaya , Kuala Lumpur, Malaysia .

Rickettsioses of the typhus group (TG) and spotted fever group (SFG) are emerging bacterial infections worldwide, especially in the tropics. Only a few studies on these pathogens and their respective clinical diseases have been conducted in Malaysia. Here, we performed a seroprevalence study among 544 healthy, afebrile indigenous people (Orang Asli) from peninsular Malaysia for TG and SFG rickettsioses in nine rural and peri-urban settlements. Read More

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http://dx.doi.org/10.1089/vbz.2018.2391DOI Listing
December 2018

Evaluation of the possible use of genus Mentha derived essential oils in the prevention of SENLAT syndrome caused by Rickettsia slovaca.

J Ethnopharmacol 2019 Mar 6;232:55-61. Epub 2018 Dec 6.

Biomedical Research Center, Institute of Virology, Slovak Academy of Sciences, Dúbravská cesta 9, 845 05 Bratislava, Slovakia.

Ethnopharmacological Relevance: Essential oils and essential oil bearing medicinal and culinary plants have a long tradition of being used to combat infection, treat various conditions, and promote and restore health. Mint oils are traditionally applied to repel insects and treat various conditions including wounds, skin infections, inflammation, eczema, urticaria, psoriasis, scabies and insect bites. They are among essential oils promoted as a natural way to prevent tick-borne diseases and recommended as ingredients in various homemade repellent mixtures and tick-bite treatments. Read More

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http://dx.doi.org/10.1016/j.jep.2018.12.005DOI Listing
March 2019
2 Reads

Development of a rapid and visual detection method for Rickettsia rickettsii combining recombinase polymerase assay with lateral flow test.

PLoS One 2018 26;13(11):e0207811. Epub 2018 Nov 26.

Huadong Research Institute for Medicine and Biotechniques, Nanjing, Jiangsu, China.

Objectives: Rickettsia rickettsii is the causative agent of Rocky Mountain spotted fever, which is the most severe spotted fever group (SFG) rickettsiosis. Developing a simple and reliable detection method is required.

Methods: A detection method for R. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0207811PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257923PMC
November 2018
11 Reads

Ocular manifestations of in South India.

Indian J Ophthalmol 2018 Dec;66(12):1840-1844

Resident, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Salem, Tamil Nadu, India.

Purpose: Among the major groups of rickettsiosis, the commonly reported diseases in India are: (a) Typhus group induced-scrub typhus, murine flea-borne typhus; (b) Spotted fever group induced-Indian tick typhus; and (c) Q fever. Though many scrub typhus outbreaks have been reported from India, only one outbreak of spotted fever-serologically proven Indian tick typhus (Rickettsia conorii)-has been reported. We report for the first time ocular manifestations of serologically proven R. Read More

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http://dx.doi.org/10.4103/ijo.IJO_420_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256869PMC
December 2018
10 Reads

Tick- and flea-borne rickettsioses in Tizi-Ouzou, Algeria: Implications for travel medicine.

Travel Med Infect Dis 2018 Nov - Dec;26:51-57. Epub 2018 Nov 9.

Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, IHU-Méditerranée Infection, Marseille, France. Electronic address:

Background: In Algeria, Mediterranean spotted fever (MSF), caused by Rickettsia conorii conorii and transmitted by Rhipicephalus sanguineus, is endemic. However, the documentation of cases is rare due to a lack of laboratory facilities. Our aim was to screen for rickettsioses in patients with fever, rash and a possible inoculation eschar. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14778939183040
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http://dx.doi.org/10.1016/j.tmaid.2018.11.005DOI Listing
January 2019
14 Reads

Seroprevalence of spotted fever group and typhus group rickettsiae in individuals with acute febrile illness from Gorakhpur, India.

Int J Infect Dis 2019 Feb 2;79:195-198. Epub 2018 Nov 2.

Indian Council of Medical Research, New Delhi, India.

Background: The aim of this study was to estimate the seroprevalence of spotted fever group (SFG) and typhus group (TG) rickettsiae among individuals with acute febrile illness (AFI) in the scrub typhus endemic district of Gorakhpur in India. This district is one of the worst affected by annual seasonal acute encephalitis syndrome (AES) outbreaks.

Methods: Antibodies against SFG and TG rickettsiae and the associated risk factors were determined in 294 individuals presenting with an AFI, encountered during a community-based survey conducted during the AES outbreak period October-November 2016. Read More

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http://dx.doi.org/10.1016/j.ijid.2018.10.024DOI Listing
February 2019
2 Reads
2.330 Impact Factor

Epidemiological characterization of incident cases of Rickettsia infection in rural areas of Urabá region, Colombia.

PLoS Negl Trop Dis 2018 10 31;12(10):e0006911. Epub 2018 Oct 31.

Grupo de Epidemiología, Facultad Nacional de Salud Pública, Universidad de Antioquia, Medellín, Colombia.

Introduction: Most of the studies related to rickettsial infection in Colombia are cross-sectional because of the challenge in conducting prospective studies on infectious disease that may have a difficult diagnosis. Although cross-sectional studies are essential to detect people exposed to rickettsiae, they are not suited to demonstrate the recent circulation of this pathogen in areas at risk of transmission.

Objective: To characterize the epidemiology of incident cases of Spotted fever group (SFG) rickettsial infection in humans and equines from rural areas of Urabá region in Colombia where outbreaks of rickettsiae previously occurred. Read More

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https://journals.plos.org/plosntds/article/file?id=10.1371/j
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http://dx.plos.org/10.1371/journal.pntd.0006911
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http://dx.doi.org/10.1371/journal.pntd.0006911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242695PMC
October 2018
5 Reads

Vector Tick Transmission Model of Spotted Fever Rickettsiosis.

Am J Pathol 2019 Jan 11;189(1):115-123. Epub 2018 Oct 11.

Department of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas.

Many aspects of rickettsial infections have been characterized, including pathogenic and immune pathways and mechanisms of rickettsial survival within the vertebrate host and tick vector. However, very few studies are focused on the complex pathogen-vector-host interactions during tick feeding. Therefore, our objective was to develop a tick transmission model of the spotted fever group of rickettsial infections to study the initial events in disease development. Read More

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http://dx.doi.org/10.1016/j.ajpath.2018.09.005DOI Listing
January 2019

Detection of zoonotic agents and a new Rickettsia strain in ticks from donkeys from South Africa: Implications for travel medicine.

Travel Med Infect Dis 2018 Nov - Dec;26:43-50. Epub 2018 Oct 9.

Centre of Rickettsiosis and Arthropod-Borne Diseases, Hospital Universitario San Pedro-CIBIR, Logroño, La Rioja, Spain. Electronic address:

Background: In rural South Africa, people are in close contact with tick-infested donkeys. This study aimed to investigate the presence of spotted fever group Rickettsia, Anaplasma, Ehrlichia and Coxiella species in these arthropods.

Method: 376 ticks (7 species) from donkeys from Limpopo Province (South Africa) were pooled and analyzed using PCR assays for the bacterium detection. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14778939183035
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http://dx.doi.org/10.1016/j.tmaid.2018.10.007DOI Listing
January 2019
2 Reads

Rickettsia fournieri sp. nov., a novel spotted fever group rickettsia from Argas lagenoplastis ticks in Australia.

Int J Syst Evol Microbiol 2018 Dec 11;68(12):3781-3784. Epub 2018 Oct 11.

4​UMR MEPHI, Aix-Marseille University, IRD, Assistance Publique-Hôpitaux de Marseille, Institut Hospitalo-Universitaire Méditerranée Infection, 19-21 Boulevard JeanMoulin, 13005 Marseille, France.

Strain AUS118 was isolated from an Argas lagenoplastis tick collected from the nest of a Petrochelidon ariel (fairy martin) in Australia in 2013. Microscopic observation of infected cell cultures indicated this strain had a morphology and intracellular location typical of Rickettsiaspecies. Phylogenetic analysis of this strain based firstly on multi-locus sequence analysis and subsequently on whole genome analysis demonstrated that AUS118 was most closely related to, but divergent from Rickettsia japonica and Rickettsia heilongjiangensis. Read More

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http://www.microbiologyresearch.org/content/journal/ijsem/10
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http://dx.doi.org/10.1099/ijsem.0.003057DOI Listing
December 2018
2 Reads

[Fatal spotted fever in Salta province].

Medicina (B Aires) 2018 ;78(5):356-359

Departamento de Medicina Interna y Terapia Intensiva, Hospital Papa Francisco, Salta, Argentina. E-mail:

We describe the case of a 17-year-old male patient living in Salta city who, 10 days after visiting a rural area in Salta province, was hospitalized for febrile seizures. Shortly after admission, he developed an exanthema followed by a multiple organ dysfunction that evolved to irreversible septic shock followed by death 48 hours after admission. Serological diagnosis -high IgM and IgG anti-Rickettsia spp. Read More

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January 2018
17 Reads

Serological evidence of spotted fever group rickettsiosis in and around Puducherry, south India-A three years study.

J Vector Borne Dis 2018 Apr-Jun;55(2):144-150

Department of General Medicine and Microbiology, Indira Gandhi Govt. General Hospital and Post Graduate Institute, Puducherry, India.

Background & Objectives: Rickettsial diseases are important re-emerging infections that mostly go unnoticed or are misdiagnosed. Though few case reports of Indian tick typhus have been reported in Indian literature in the past 10 yr, prevalence surveys are few and far between. The objective of this research was to study the seroprevalence of spotted fever (SF) group rickettsiosis and its coinfection with scrub typhus (ST) in Puducherry region of south India, as these two diseases may show similar clinical presentations. Read More

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http://dx.doi.org/10.4103/0972-9062.242562DOI Listing
December 2018
6 Reads

Spotted Fever Rickettsiosis in a Wildlife Researcher in Sabah, Malaysia: A Case Study.

Trop Med Infect Dis 2018 Mar 6;3(1). Epub 2018 Mar 6.

Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford OX3 7FZ, UK.

We present evidence for a case of spotted fever rickettsiosis with severe complications in a young adult male. Although spotted fever group rickettsiae (SFGR) have been reported as the most prevalent cause of rickettsiosis in rural areas of Sabah, Malaysia since the 1980s, this is the first detailed case report of suspected SFGR in the state. Current data on the prevalence, type, and thorough clinical reports on complications of SFGR and other rickettsioses in Sabah is lacking and required to raise the awareness of such diseases. Read More

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http://dx.doi.org/10.3390/tropicalmed3010029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136627PMC
March 2018
1 Read

The Re-Emergence and Emergence of Vector-Borne Rickettsioses in Taiwan.

Trop Med Infect Dis 2017 Dec 21;3(1). Epub 2017 Dec 21.

Institute of Environmental Health, College of Public Health, National Taiwan University, No. 17, Xu-Zhou Road, Taipei 100, Taiwan.

Rickettsial diseases, particularly vector-borne rickettsioses (VBR), have a long history in Taiwan, with studies on scrub typhus and murine typhus dating back over a century. The climatic and geographic diversity of Taiwan's main island and its offshore islands provide many ecological niches for the diversification and maintenance of rickettsiae alike. In recent decades, scrub typhus has re-emerged as the most prevalent type of rickettsiosis in Taiwan, particularly in eastern Taiwan and its offshore islands. Read More

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http://dx.doi.org/10.3390/tropicalmed3010001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136612PMC
December 2017
16 Reads

Molecular evidence and diversity of the spotted-fever group Rickettsia spp. in small mammals from natural, suburban and urban areas of Eastern Slovakia.

Ticks Tick Borne Dis 2018 09 23;9(6):1400-1406. Epub 2018 Jun 23.

Institute of Parasitology, Slovak Academy of Sciences, Hlinkova 3, 040 01 Košice, Slovakia; Institute of Zoology, Slovak Academy of Sciences, Dúbravská cesta 9, 845 06 Bratislava, Slovakia. Electronic address:

Rickettsiae of the spotted fever group are considered as emerging pathogens; ticks, fleas and mites are known to be their vectors. However, the prevalence and species diversity of rickettsiae in small mammals and the role of these hosts in the circulation of bacteria are much less studied. During 2014-2016, a total of 250 small mammals (Apodemus agrarius, Apodemus flavicollis, Apodemus uralensis, Myodes glareolus, Crocidura leucodon, Crocidura suaveolens, Micromys minutus, Microtus arvalis, Microtus subterraneus, Neomys fodiens and Sorex minutus) were captured in natural, suburban and urban habitats of eastern Slovakia. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.06.011DOI Listing
September 2018
2 Reads

Tick-borne zoonoses in the Order Rickettsiales and Legionellales in Iran: A systematic review.

PLoS Negl Trop Dis 2018 09 11;12(9):e0006722. Epub 2018 Sep 11.

Department of Pathobiology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.

Background: Tick-borne zoonoses in the Order Rickettsiales and Legionellales cause infections that often manifest as undifferentiated fevers that are not easy to distinguish from other causes of acute febrile illnesses clinically. This is partly attributed to difficulty in laboratory confirmation since convalescent sera, specific diagnostic reagents, and the required expertise may not be readily available. As a result, a number of tick-borne zoonoses are underappreciated resulting in unnecessary morbidity, mortality and huge economic loses. Read More

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https://dx.plos.org/10.1371/journal.pntd.0006722
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http://dx.doi.org/10.1371/journal.pntd.0006722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181433PMC
September 2018
29 Reads

Mediterranean spotted fever rickettsiosis in Italy, 2001-2015: Spatio-temporal distribution based on hospitalization records.

Ticks Tick Borne Dis 2019 01 3;10(1):43-50. Epub 2018 Sep 3.

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

The Mediterranean spotted fever (MSF) rickettsiosis is the predominant rickettsial disease among the spotted fever group (SFG) rickettsiae in the Mediterranean countries and North Africa. Its causative agent is Rickettsia conorii, although, SFG rickettsiosis - cases due to Rickettsia monacensis, Rickettsia massiliae and Rickettsia aeschlimannii were also described. A retrospective study based on hospital discharge records with a diagnosis of SFG rickettsiosis was carried out to describe the spatial pattern, the trend of the disease, and the epidemiological characteristics of persons hospitalized in the period 2001-2015. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.09.001DOI Listing
January 2019
1 Read

Evidence of locally acquired spotted fever group rickettsioses in Southeast Texas, 2008-2016.

Zoonoses Public Health 2018 11 27;65(7):897-901. Epub 2018 Aug 27.

Section of Pediatric Tropical Medicine, Department of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas.

We identified six paediatric case-patients from southeast Texas diagnosed with confirmed or probable Spotted Fever Group Rickettsiosis (SFGR) between 2008 and 2016. Only one case had a history of travel to an endemic area. Clinical and laboratory findings strongly suggest locally acquired Rocky Mountain Spotted Fever in one Houston patient. Read More

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http://dx.doi.org/10.1111/zph.12518DOI Listing
November 2018
3 Reads

Clinicopathological study on rickettsial spotted fever from south India.

Trop Doct 2018 Oct 23;48(4):325-329. Epub 2018 Aug 23.

2 Department of Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.

In a prospective study conducted between November 2006 and April 2008 of 35 patients (male:female ratio 2:1) with proven rickettsial spotted fever, a generalised rash with involvement of palms and soles were seen in 80% of patients. Vasculitis on histopathology of rash was seen in 54%. Read More

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http://dx.doi.org/10.1177/0049475518794580DOI Listing
October 2018
10 Reads

Serologic assessment for exposure to spotted fever group rickettsiae in dogs in the Arizona-Sonora border region.

Zoonoses Public Health 2018 12 21;65(8):984-992. Epub 2018 Aug 21.

Arizona Department of Health Services, Office of Infectious Disease Services, Phoenix, Arizona.

Rocky Mountain spotted fever (RMSF) is a severe tick-borne rickettsial illness. In the south-western United States and Mexico, RMSF displays unique epidemiologic and ecologic characteristics, including Rhipicephalus sanguineus sensu lato (brown dog tick) as the primary vector. Expansion and spread of the disease from hyperendemic regions of Arizona or Mexico to new areas is a key public health concern. Read More

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http://dx.doi.org/10.1111/zph.12517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217800PMC
December 2018
2 Reads

Exposure of Owned Dogs and Feeding Ticks to Spotted Fever Group Rickettsioses in Central Italy.

Vector Borne Zoonotic Dis 2018 12 21;18(12):704-708. Epub 2018 Aug 21.

1 Department of Veterinary Medicine, University of Perugia , Perugia, Italy .

Dogs may be useful sentinels for public health monitoring of spotted fever group rickettsioses (SFGR). The aim of this study was to determine the exposure to SFGR among dogs and feeding ticks in central Italy. A total of 344 dogs and 607 adult ticks (395 Rhipicephalus sanguineus and 212 Ixodes ricinus specimens) collected from the coats of sampled animals were included in the study. Read More

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http://dx.doi.org/10.1089/vbz.2018.2303DOI Listing
December 2018
2.300 Impact Factor

Detection of Rickettsia monacensis and Rickettsia amblyommatis in ticks collected from dogs in Costa Rica and Nicaragua.

Ticks Tick Borne Dis 2018 09 6;9(6):1565-1572. Epub 2018 Aug 6.

Institute for Parasitology, Centre for Infection Medicine, University of Veterinary Medicine Hannover, Buenteweg 17, 30559 Hanover, Germany. Electronic address:

The neotropical climate of Central America provides ideal conditions for ticks, which may transmit several human pathogens, including spotted-fever group Rickettsia. Dogs may act as sentinels or reservoirs for human tick-borne diseases due to shared tick species. Here, ticks were collected from 680 client-owned dogs in Nicaragua and Costa Rica, and a total of 316 tick pools were investigated for Rickettsia infection by quantitative real-time PCR (qPCR) targeting the gltA gene. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.08.002DOI Listing
September 2018
8 Reads

Effects of Rickettsia amblyommatis Infection on the Vector Competence of Amblyomma americanum Ticks for Rickettsia rickettsii.

Vector Borne Zoonotic Dis 2018 11 10;18(11):579-587. Epub 2018 Aug 10.

Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention , Atlanta, Georgia .

Although Dermacentor spp. ticks are considered the primary vectors of Rickettsia rickettsii in the United States, other North American tick species are also capable of transmitting the agent, including the lone star tick-Amblyomma americanum. The lone star tick is an aggressive human-biting tick abundant in the South, Central, and Mid-Atlantic United States, which has been shown to be a competent vector of R. Read More

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http://dx.doi.org/10.1089/vbz.2018.2284DOI Listing
November 2018
3 Reads

First molecular detection of the human pathogen Rickettsia raoultii and other spotted fever group rickettsiae in Ixodid ticks from wild and domestic mammals.

Parasitol Res 2018 Nov 4;117(11):3421-3429. Epub 2018 Aug 4.

Istituto Zooprofilattico Sperimentale della Sardegna, Via Duca degli Abruzzi, 8, 07100, Sassari, Italy.

Tick-borne rickettsioses are recognized as emerging vector-borne infections capable of infecting both human and animal hosts worldwide. This study focuses on the detection and molecular identification of species belonging to the genus Rickettsia in ticks sampled from human, vegetation, and domestic and wild vertebrates in Sardinia. Ticks were tested by PCR targeting gltA, ompA, and ompB genes, followed by sequencing analysis. Read More

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http://dx.doi.org/10.1007/s00436-018-6036-yDOI Listing
November 2018

Septic Shock Caused by Rocky Mountain Spotted Fever in a Suburban Texas Patient with Pet Dog Exposure: A Case Report.

Am J Case Rep 2018 Aug 4;19:917-919. Epub 2018 Aug 4.

Department of Internal Medicine, The Methodist Hospital, Houston, TX, USA.

BACKGROUND Rocky Mountain spotted fever (RMSF) is associated with high mortality and requires prompt identification and treatment to ensure better outcomes. CASE REPORT We describe an advanced case of RMSF in a 45-year-old female patient with pet dog exposure who presented with altered mental status, dyspnea, and ataxia progressing to septic shock and acute hypoxic respiratory failure requiring intubation and mechanical ventilation. CONCLUSIONS This case illustrates the importance of keeping RMSF in the differential diagnosis in patient populations outside of the usual geographic areas of incidence in the appropriate clinical setting. Read More

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http://dx.doi.org/10.12659/AJCR.909636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091339PMC
August 2018
12 Reads

The prevalence and clinical characteristics of tick-borne diseases at One Sentinel Hospital in Northeastern China.

Parasitology 2019 Feb 1;146(2):161-167. Epub 2018 Aug 1.

State Key Laboratory of Pathogen and Biosecurity,Beijing Institute of Microbiology and Epidemiology,Beijing 100071,P.R. China.

Northeastern China is a region of high tick abundance, multiple tick-borne pathogens and likely human infections. The spectrum of diseases caused by tick-borne pathogens has not been objectively evaluated in this region for clinical management and for comparison with other regions globally where tick-transmitted diseases are common. Based on clinical symptoms, PCR, indirect immunofluorescent assay and (or) blood smear, we identified and described tick-borne diseases from patients with recent tick bite seen at Mudanjiang Forestry Central Hospital. Read More

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http://dx.doi.org/10.1017/S0031182018001178DOI Listing
February 2019
8 Reads

Zoonotic Anaplasma phagocytophilum, Ehrlichia canis, Dirofilaria immitis, Borrelia burgdorferi, and spotted fever group rickettsiae (SFGR) in different types of dogs.

Parasitol Res 2018 Nov 31;117(11):3407-3412. Epub 2018 Jul 31.

Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan.

Dogs can carry and share zoonotic pathogens with humans. This problem is understudied in different parts of the world, including Jordan. This study determined the prevalence of Anaplasma phagocytophilum, Ehrlichia canis, Dirofilaria immitis, and Borrelia burgdorferi using the SNAP 4Dx Plus test and spotted fever group rickettsiae (SFGR) using enzyme immunoassay IgG test in different types of dogs (farm/breeding, police, and stray) in Jordan. Read More

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http://link.springer.com/10.1007/s00436-018-6033-1
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http://dx.doi.org/10.1007/s00436-018-6033-1DOI Listing
November 2018
9 Reads

Abiotic and habitat drivers of tick vector abundance, diversity, phenology and human encounter risk in southern California.

PLoS One 2018 31;13(7):e0201665. Epub 2018 Jul 31.

Department of Biology, Stanford University, Stanford, California, United States of America.

The distribution, abundance and seasonal activity of vector species, such as ticks and mosquitoes, are key determinants of vector-borne disease risk, and are strongly influenced by abiotic and habitat conditions. Despite the numerous species of tick vectors in the heavily populated North American West Coast, all but Ixodes pacificus, the primary vector of the Lyme disease spirochete, is poorly characterized with regard to seasonal activity patterns and fine scale drivers of distribution and abundance, particularly in heavily populated regions of southern California. This lack of knowledge inhibits both scientific understanding and public health efforts to minimize vector exposure and risk of pathogen transmission to humans. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201665PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067749PMC
February 2019
1 Read

Case Report: Typhoid Fever and Spotted Fever Group Rickettsiosis Presenting Concomitantly in an Indian Immigrant.

Am J Trop Med Hyg 2018 Oct;99(4):864-866

The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.

We present a rare case of an Indian immigrant suffering from concomitant infection of and spotted fever group . We discuss the scarce reports of dual infections from the developing world and the related diagnostic challenges. Read More

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http://dx.doi.org/10.4269/ajtmh.17-0770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159590PMC
October 2018
3 Reads

[A complicated clinical course of tick-borne rickettsiosis after safari in South Africa].

Dtsch Med Wochenschr 2018 08 30;143(15):1116-1119. Epub 2018 Jul 30.

IV. Medizinische Klinik und Poliklinik der LMU, München.

History: A healthy 41 year old man was bitten by a tick while on safari in the Kruger National Park in South Africa. He developed severe fever and malaise 5 days later. A characteristic red skin sore with a dark centre and surrounding erythema (eschar, tache noir) developed at the site of the tick bite. Read More

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http://dx.doi.org/10.1055/a-0622-7606DOI Listing
August 2018
7 Reads

A review of the genus in Central America.

Res Rep Trop Med 2018 29;9:103-112. Epub 2018 Jun 29.

Vector Research Laboratory, Tropical Diseases Research Center, Faculty of Microbiology, University of Costa Rica, San Jose, Costa Rica.

In this paper, we present a historical review of rickettsiosis in Central America and also the most recent findings of in ectoparasites. All countries of Central America have records of rickettsiosis. Regarding the typhus group rickettsioses, there is clinical or serological evidence of in Guatemala, in Panama, Guatemala, and Costa Rica and unidentified species of the typhus group in El Salvador. Read More

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http://dx.doi.org/10.2147/RRTM.S160951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047601PMC
June 2018
15 Reads

Rickettsia Species Isolated from Dermacentor occidentalis (Acari: Ixodidae) from California.

J Med Entomol 2018 Oct;55(6):1555-1560

Vector-Borne Disease Section, Division of Communicable Disease Control, California Department of Public Health, Richmond, CA.

The Pacific Coast tick (Dermacentor occidentalis Marx, 1892) is one of the most widely distributed and frequently encountered tick species in California. This tick is the primary vector of an unclassified spotted fever group rickettsial pathogen, designated currently as Rickettsia 364D, the etiologic agent of a recently recognized tick-borne rickettsiosis known as Pacific Coast tick fever. Despite intensified interest in this pathogen, important questions remain regarding its taxonomic status and possible variations in genotype among different strains that could influence its pathogenicity. Read More

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http://dx.doi.org/10.1093/jme/tjy100DOI Listing
October 2018
3 Reads

Molecular survey of Rickettsia spp. in the Neotropical deer tick Haemaphysalis juxtakochi from Brazilian Pampa.

Parasitol Res 2018 Oct 6;117(10):3293-3298. Epub 2018 Jul 6.

Instituto de Pesquisas Veterinárias Desidério Finamor (IPVDF), Estrada do Conde, 6000, mail box 47, Eldorado do Sul, Rio Grande do Sul, 92990-000, Brazil.

Spotted fever (SF) is a tick-borne disease associated with Rickettsia spp.. In the Pampa biome, Southern Brazil, cases of SF seem to be strongly linked with the practice of hunting wild animals. Read More

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http://dx.doi.org/10.1007/s00436-018-5996-2DOI Listing
October 2018
7 Reads

Spotted fever group Rickettsiae in Ticks from Missouri.

Ticks Tick Borne Dis 2018 09 25;9(6):1395-1399. Epub 2018 Jun 25.

Laboratorio de Investigación en Vectores, Centro de Investigación en Enfermedades Tropicales, Facultad de Microbiología, Universidad de Costa Rica, San Pedro, Costa Rica. Electronic address:

Tick-borne rickettsioses pose a major health threat among vector-borne infections in Missouri but there are some uncertainties regarding the vector competence and range of tick species, as well as the virulence of certain bacterial species. A survey was developed and implemented to assess local healthcare practitioners' awareness of the prevalence and diagnosis of tick-borne diseases. In addition, ticks collected from rural areas of St. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.06.008DOI Listing
September 2018

The Rickettsial Ankyrin Repeat Protein 2 Is a Type IV Secreted Effector That Associates with the Endoplasmic Reticulum.

MBio 2018 06 26;9(3). Epub 2018 Jun 26.

Host-Parasite Interactions Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana, USA

Strains of , the tick-borne agent of Rocky Mountain spotted fever, vary considerably in virulence. Genomic comparisons of strains have identified a relatively small number of genes divergent in an avirulent strain. Among these is one annotated as ankyrin repeat protein 2 (RARP-2). Read More

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http://mbio.asm.org/lookup/doi/10.1128/mBio.00975-18
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http://dx.doi.org/10.1128/mBio.00975-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020290PMC
June 2018
12 Reads

Molecular evidence of in spleen of wild boars in northeastern Algeria.

New Microbes New Infect 2018 Jul 29;24:17-20. Epub 2018 Mar 29.

Université Chadli Bendjedid, département des sciences vétérinaires, El Tarf, Algeria.

Using molecular assays, the agent of a spotted fever group rickettsiosis resulting in scalp eschar and neck lymphadenopathy after tick bite, was assessed in 92 spleens recovered from 117 wild boars hunted in the far northeast of Algeria. was detected in 5.4% of tested wild boar spleens. Read More

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http://dx.doi.org/10.1016/j.nmni.2018.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005159PMC
July 2018
7 Reads

Mediterranean Spotted Fever in Children: Study of a Portuguese Endemic Region.

Acta Med Port 2018 Apr 30;31(4):196-200. Epub 2018 Apr 30.

Pediatric Department. Centro Hospitalar de Trás-os-Montes e Alto Douro. Vila Real, Portugal.

Introduction: Mediterranean spotted fever is an infectious disease included in the human rickettsiosis group, with its main distribution in the Mediterranean and South European countries. It is an endemic disease in Portugal, with dogs acting as the main domestic reservoir. Children are a particularly vulnerable group due to their close contact with household animals and by frequently playing outdoors. Read More

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http://dx.doi.org/10.20344/amp.9713DOI Listing
April 2018
9 Reads

Fatal case of spotted fever in a patient from Northeastern Brazil.

Rev Inst Med Trop Sao Paulo 2018 28;60:e21. Epub 2018 May 28.

Laboratório de Referência Nacional para Vetores das Riquetsioses, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil.

Spotted fevers are diseases caused by bacterial agents belonging to the spotted-fever (SF) group of the genus Rickettsia. The first documented case of SF in Pernambuco State, Northeast Brazil, was reported here. Also, it is the first case described of fatal SF in Northeast region of Brazil. Read More

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http://dx.doi.org/10.1590/s1678-9946201860021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975566PMC
June 2018
18 Reads

Records of ticks on humans in Rio Grande do Sul state, Brazil.

Ticks Tick Borne Dis 2018 07 18;9(5):1296-1301. Epub 2018 May 18.

Instituto de Pesquisas Veterinárias Desidério Finamor (IPVDF), Eldorado do Sul, RS, Brazil.

More than seventy tick species have been reported in Brazil. Despite the emergence of tick-borne diseases in Neotropical region, there are still limited data available on tick species parasitizing humans in Brazil. Rio Grande do Sul is the southernmost state of Brazil, comprising the only part of Brazilian territory inside the Pampa biome, as well as the transition between subtropical and temperate zones. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.05.010DOI Listing
July 2018
8 Reads

Rare presentation of rickettsial infection as purpura fulminans: a case report.

J Med Case Rep 2018 May 26;12(1):145. Epub 2018 May 26.

Department of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.

Background: Purpura fulminans is an acute life-threatening disorder characterized by intravascular thrombosis and hemorrhagic infarction of the skin complicated with disseminated intravascular coagulation. It is commonly seen in acute infections following meningococcal and streptococcal infections. Few cases of purpura fulminans following rickettsial infections have been described in the literature. Read More

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http://dx.doi.org/10.1186/s13256-018-1672-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970498PMC
May 2018
3 Reads

Ocular manifestations of rickettsia in children: common but frequently overlooked.

BMJ Case Rep 2018 May 18;2018. Epub 2018 May 18.

Ophthalmology Department, Centro Hospitalar Tondela-Viseu, Viseu, Portugal.

We review two cases of ocular manifestations of infection in children. A girl who presented unilateral visual loss with focal retinitis and macular oedema and a boy with unilateral central scotoma and bilateral anterior uveitis. Progressive functional and anatomic recovery was observed after oral antibiotics and steroids were initiated. Read More

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http://dx.doi.org/10.1136/bcr-2017-222809DOI Listing
May 2018
4 Reads

Case 14-2018: A 68-Year-Old Woman with a Rash, Hyponatremia, and Uveitis.

N Engl J Med 2018 May;378(19):1825-1833

From the Departments of Medicine (M.L.P., E.P.H.) and Pathology (R.K.F., K.C.C.), Massachusetts General Hospital, and the Departments of Medicine (M.L.P., E.P.H.) and Pathology (R.K.F., K.C.C.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1800337DOI Listing

Timeliness in the notification of spotted fever in Brazil: Evaluating compulsory reporting strategies and digital disease detection.

Int J Infect Dis 2018 Jul 3;72:16-18. Epub 2018 May 3.

Seção de Epidemiologia Hospitalar, Hospital de Clínicas, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil; Departamento de Vigilância em Saúde de Campinas, Campinas, São Paulo, Brazil.

Spotted fever is caused by rickettsia species, and is the most important tick-borne disease. In Brazil, it requires national compulsory notification to the Ministry of Health. Since 2007, all suspected cases of spotted fever have been integrated into the Notifiable Diseases Information System (SINAN). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S12019712183440
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http://dx.doi.org/10.1016/j.ijid.2018.04.4317DOI Listing
July 2018
5 Reads

Vital Signs: Trends in Reported Vectorborne Disease Cases - United States and Territories, 2004-2016.

MMWR Morb Mortal Wkly Rep 2018 May 4;67(17):496-501. Epub 2018 May 4.

Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Fort Collins, Colorado.

Introduction: Vectorborne diseases are major causes of death and illness worldwide. In the United States, the most common vectorborne pathogens are transmitted by ticks or mosquitoes, including those causing Lyme disease; Rocky Mountain spotted fever; and West Nile, dengue, and Zika virus diseases. This report examines trends in occurrence of nationally reportable vectorborne diseases during 2004-2016. Read More

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http://www.cdc.gov/mmwr/volumes/67/wr/mm6717e1.htm?s_cid=mm6
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http://dx.doi.org/10.15585/mmwr.mm6717e1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933869PMC
May 2018
64 Reads

Analysis of the environmental and host-related factors affecting the distribution of the tick Dermacentor marginatus.

Exp Appl Acarol 2018 Jun 30;75(2):209-225. Epub 2018 Apr 30.

Department of Veterinary Sciences, University of Turin, Via L. da Vinci 44, 10095, Grugliasco, Turin, Italy.

Understanding and responding to the ecological, social and economic conditions that facilitate disease emergence and transmission represents a substantial challenge for epidemiologists and health professionals. In this article we integrate knowledge about the human and the vector population, to provide a context from which to examine the underlying causal factors of D. marginatus-borne diseases emergence in the study area. Read More

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http://dx.doi.org/10.1007/s10493-018-0257-8DOI Listing
June 2018
6 Reads

Evaluation of Diagnostic Assay for Rickettsioses Using Duplex Real-Time PCR in Multiple Laboratories in Japan.

Jpn J Infect Dis 2018 Jul 27;71(4):267-273. Epub 2018 Apr 27.

Department of Food and Nutritional Sciences, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka.

Tsutsugamushi disease and Japanese spotted fever are representative rickettsioses in Japan, and are caused by infection with Orientia tsutsugamushi and Rickettsia japonica, respectively. For molecular-based diagnosis, conventional PCR assays, which independently amplify respective rickettsial DNA, are usually used; however, this approach is time-consuming. Here, we describe a new duplex real-time PCR assay for the simultaneous detection of O. Read More

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http://dx.doi.org/10.7883/yoken.JJID.2017.447DOI Listing
July 2018
7 Reads