2,287 results match your criteria Rhinology[Journal]


Frontal sinus ablation (Riedel-Mosher's procedure): indications and role in the endonasal endoscopic era.

Rhinology 2019 Apr 15. Epub 2019 Apr 15.

Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, ASST Sette Laghi, Ospedale di Circolo e Fondazione Macchi, Varese, Italy.

Background: The aim of this article is to describe the Riedel-Mosher's surgical technique and identify its current role in the endoscopic endonasal era based on the experience of a tertiary care medical centre. It also provides a brief excursus on materials available for frontal reconstruction.

Methods: A retrospective review of patients submitted to Riedel-Mosher's procedure from 2005 to 2018 at a single tertiary care centre was carried out. Read More

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http://dx.doi.org/10.4193/Rhin18.197DOI Listing
April 2019
1 Read

Cold dry air provocation is a reliable diagnostic tool in nonallergic rhinitis.

Rhinology 2019 Apr 9. Epub 2019 Apr 9.

Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China.

Background: No diagnostic criteria have been available for nonallergic rhinitis (NAR) to this point in time. Nonspecific nasal hyperresponsiveness (NHR), which could be efficiently assessed by cold dry air (CDA) provocation, is an essential feature of NAR. Thus, this study's purpose was to assess the diagnostic value of CDA provocation in discriminating patients with NAR from healthy individuals. Read More

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http://dx.doi.org/10.4193/Rhin18.187DOI Listing

Patient Advisory Board for Chronic Rhinosinusitis - A EUFOREA initiative.

Rhinology 2019 Apr 9. Epub 2019 Apr 9.

European Forum for Research and Education in Allergy and Airway diseases (EUFOREA), Brussels, Belgium.

Despite the high prevalence of chronic rhinosinusitis (CRS) and its impact on patients' quality of life, no European patient organization that advocates for patients with CRS currently exists. To fill this gap and give a voice to CRS patients, EUFOREA has created a patient advisory board, whose goal is to better understand the real-life needs of patients, to raise awareness at political level and to involve patients in the development of novel integrated solutions to accelerate access to accurate diagnosis and treatments. This report summarizes the key discussion points from the kick-off meeting of the board on the 8th June 2018 and provides an outline of the key objectives for the future. Read More

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http://dx.doi.org/10.4193/Rhin19.012DOI Listing

Complications and number of follow-up visits after using septal stapler in septoplasty.

Rhinology 2019 Apr 2. Epub 2019 Apr 2.

Department of Otorhinolaryngology, University of Helsinki, Helsinki, Finland.

Background: Septoplasties have traditionally been closed with transseptal sutures, silicone splints, or packing with nasal tamponade. In 2015, our clinic began to employ a septal stapler. The stapler adheres the mucosa to the septal cartilage with bioresorbable staples, replacing both sutures and silicone splints and limiting the use of nasal tamponade for bleeding cases. Read More

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https://www.rhinologyjournal.com/Abstract.php?id=1886
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http://dx.doi.org/10.4193/Rhin18.142DOI Listing
April 2019
7 Reads

Control of allergic rhinitis with MP-AzeFlu: a noninterventional study of a Swedish cohort.

Rhinology 2019 Apr 2. Epub 2019 Apr 2.

Department of Clinical Sciences, Intervention and Technology, Division of Otorhinolaryngology, Karolinska Instituet, Stockholm, Sweden.

Background: The European Union has prioritised allergic rhinitis (AR) control. A visual analogue scale (VAS) has been endorsed as the AR control language and embedded into the most recent MACVIA-ARIA guideline. This study assessed the effectiveness and safety of MP-AzeFlu using a VAS in a real-life study in Sweden. Read More

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http://dx.doi.org/10.4193/Rhin18.028DOI Listing
April 2019
2 Reads

Risk of mortality and cardiovascular events following macrolide prescription in chronic rhinosinusitis patients: a cohort study using linked primary care electronic health records.

Rhinology 2019 03 30. Epub 2019 Mar 30.

Department of Medical Statistics, London School of Hygiene.

Background: Macrolide antibiotics have demonstrated important anti-inflammatory and immunomodulatory properties in chronic rhinosinusitis (CRS) patients. However, reports of increased risks of cardiovascular events have led to safety concerns. We investigated the risk of all-cause and cardiac death, and cardiovascular outcomes, associated with macrolide use. Read More

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http://dx.doi.org/10.4193/Rhin18.237DOI Listing
March 2019
4 Reads

Local corticosteroids, why are they not used more / properly ?

Authors:
W J Fokkens

Rhinology 2019 Apr;57(2):81

Department of Otorhinolaryngology, Amsterdam University Medical Centres, Amsterdam, The Netherlands.

It has been almost 50 years since Niels Mygind published the first paper on the use of nasal corticosteroids. Twenty years ago, Weiner et al. showed in their systematic review that nasal corticosteroids are more effective than oral antihistamines in patients with allergic rhinitis. Read More

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http://dx.doi.org/10.4193/Rhin19.402DOI Listing
April 2019
1 Read

Does severe bleeding in HHT patients respond to intravenous bevacizumab? Review of the literature and case series.

Rhinology 2019 Mar 25. Epub 2019 Mar 25.

Department of ORL-Head and Neck Surgery, Odense University Hospital, Denmark.

Background: Hereditary Haemorrhagic Telangiectasia (HHT) is an autosomal dominant genetic disorder, with a wide variety of clinical manifestations due to the presence of multiple arteriovenous manifestations. Severe bleeding from the gastrointestinal (GI) tract and/or epistaxis presents a significant problem in a subgroup of patients and systemic bevacizumab, an angiogenesis inhibitor, has been suggested to benefit these patients.

Objective: To perform a review of the literature concerning the efficacy of systemic bevacizumab in treatment of bleeding from the nose or GI tract in patients with HHT, including patients from our own HHT-center. Read More

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http://dx.doi.org/10.4193/Rhin18.289DOI Listing

Azelastine nasal spray inhibiting sympathetic function on human nasal mucosa in patients with allergy rhinitis.

Rhinology 2019 Mar 19. Epub 2019 Mar 19.

Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center.

Background: Azelastine hydrochloride (azelastine) nasal spray is a histamine receptor-1 (H1) antagonist often used in treating allergic rhinitis to relieve its symptoms. However, the effects of azelastine to influence decongestion on human nasal mucosa in patients with allergic rhinitis are not yet fully explored and merit further exploration. The effects of azelastine on the vasocontractile responses generated by smooth muscles in the vascular structures of human nasal mucosa were investigated directly in vitro. Read More

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http://dx.doi.org/10.4193/Rhin18.274DOI Listing
March 2019
1 Read

EPOS2020: development strategy and goals for the latest European Position Paper on Rhinosinusitis.

Rhinology 2019 Feb 27. Epub 2019 Feb 27.

Royal National Throat, Nose and Ear Hospital, UCLH, London, UK.

Background: The European Position Papers on Rhinosinusitis from 2005, 2007 and 2012 have had a measurable impact on the way this common condition with high impact on quality of life is managed around the world. EPOS2020 will be the latest iteration of the guideline, addressing new stakeholders and target users, presenting a summary of the latest literature and evolving treatment modalities, and formulating clear recommendations based on all available evidence.

Methodology: Based on the AGREE II framework, this article demonstrates how the EPOS2020 steering group will address six key areas to ensure consistency in quality and presentation of information in the latest rhinosinusitis clinical practice guideline: scope and purpose; stakeholder involvement; rigour of development; clarity of presentation; recommendations and applicability; editorial independence. Read More

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http://dx.doi.org/10.4193/Rhin17.253DOI Listing
February 2019

A retrospective study of changes of histopathology of nasal polyps in adult Chinese in central China.

Rhinology 2019 Feb 25. Epub 2019 Feb 25.

Department of Otolaryngology - Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China.

Background: The factors contributing to the eosinophilic inflammation in chronic rhinosinusitis with nasal polyps (CRSwNP) remain elusive. This study was designed to investigate the inflammatory patterns and tissue remodeling of CRSwNP in patients from central China at two time points over 14 years apart and the influence of age.

Methods: One hundred and eight CRSwNP patients enrolled in 2000 and 2001 (group A), and 134 CRSwNP patients enrolled in 2014 and 2015 (group B) were retrospectively studied. Read More

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http://dx.doi.org/10.4193/Rhin18.070DOI Listing
February 2019
1 Read

Anatomic variations of the paranasal sinuses in the general pediatric population.

Rhinology 2019 Feb 19. Epub 2019 Feb 19.

Department of Otolaryngology, Head and Neck Surgery, Kaplan Medical Center, Rehovot, Israel.

Background: The prevalence of sinuses' anatomic variations in the healthy pediatric population has not been studied. The study describes the prevalence of known anatomic variations with regard to gender and age in this population.

Methods: A single academic institute observational cohort study. Read More

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http://dx.doi.org/10.4193/Rhin18.193DOI Listing
February 2019

Nasal self-packing for epistaxis in Hereditary Hemorrhagic Telangiectasia increases quality of life.

Rhinology 2019 Feb 10. Epub 2019 Feb 10.

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Marburg, Philipps-Universität Marburg, Marburg, Germany.

Statement Of Problem: Hereditary hemorrhagic telangiectasia (HHT) is characterized by recurrent epistaxis that can lead to a feeling of losing control. We assessed potential benefits and side effects of different nasal packings used by patients themselves.

Method Of Study: An online-questionnaire in English and German was used to analyze nasal self-packings. Read More

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http://dx.doi.org/10.4193/Rhin18.141DOI Listing
February 2019
2 Reads

A computational fluid dynamics analysis of the effects of size and shape of anterior nasal septal perforations.

Rhinology 2019 Apr;57(2):153-159

Department of Otolaryngology/Head and Neck Surgery, University of North Carolina, Chapel Hill, NC, USA.

Background: Nasal septal perforations (NSPs) often cause bleeding, crusting, obstruction, and/or whistling. The objective was to analyze the impact of anterior NSP size and shape on nasal physiology using computational fluid dynamics (CFD).

Methods: A 3-dimensional model of the nasal cavity was constructed from a radiologically normal CT scan using imaging software. Read More

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https://www.rhinologyjournal.com/Abstract.php?id=1874
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http://dx.doi.org/10.4193/Rhin18.111DOI Listing
April 2019
6 Reads

Histopathology of ethmoid mucosa versus polyp tissue in diagnosing eosinophilic mucin rhinosinusitis.

Rhinology 2019 Feb;57(1):67-72

Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Background: This study aims to compare histopathology of nasal polyp and ethmoid mucosa for diagnosing eosinophilic mucin rhinosinusitis (EMRS).

Methodology: Patients with chronic rhinosinusitis with polyps (CRSwNP) were enrolled. Using eosinophilic mucin as a reference, histopathology of polyp apex, polyp pedicle and ethmoid mucosa was compared for density of tissue eosinophil and sensitivity for diagnosing EMRS. Read More

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http://dx.doi.org/10.4193/Rhin18.068DOI Listing
February 2019
4 Reads

Free nasal floor mucosal grafting after endoscopic total ethmoidectomy for severe nasal polyposis: a pilot study.

Rhinology 2019 Jan 28. Epub 2019 Jan 28.

Rhinology Unit, Department of Otolaryngology, Hospital Universitario Virgen de la Macarena, Seville, Spain.

Background: We report a novel surgical technique based on an endonasal free mucosal graft (mucoplasty) for improving clinical results and local healing in chronic rhinosinusitis with nasal polyps (CRSwNP).

Methods: Patients diagnosed with bilateral CRSwNP scheduled for endoscopic sinus surgery were included. They underwent complete removal of anterior and posterior ethmoid cells, in addition to bilateral type III frontal sinusotomy. Read More

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https://www.rhinologyjournal.com/Abstract.php?id=1872
Publisher Site
http://dx.doi.org/10.4193/Rhin18.178DOI Listing
January 2019
7 Reads

More papers, more issues.

Authors:
W J Fokkens

Rhinology 2019 Feb;57(1)

Department of Otorhinolaryngology, Amsterdam University Medical Centres Location AMC, The Netherlands.

In recent years non-allergic rhinitis has received a lot of interest; in particular the different phenotypes, endotypes, the impact on quality of life and the potential role of IgE in local allergic rhinitis (LAR). The prevalence of LAR reported in the literature has been extremely variable (0-100%); Hamizan’s review in this issue explains many of these discrepancies. The overall prevalence of IgE in nasal secretion was found to be 10. Read More

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http://dx.doi.org/10.4193/Rhin19.401DOI Listing
February 2019
3 Reads

Is atomised intranasal cocaine systemically absorbed during endoscopic sinus surgery?

Rhinology 2019 Jan 10. Epub 2019 Jan 10.

Monash Health, Melbourne, Australia.

Background: In order to perform endoscopic sinus surgery (ESS) safely and efficiently, preparation of the nasal mucosa with vasoconstrictor agents is crucial to minimise bleeding. There is no single best method, although traditionally cocaine has been the agent of choice. However, there have been concerns over the potential for systemic side effects when applied topically. Read More

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http://dx.doi.org/10.4193/Rhin18.207DOI Listing
January 2019
1 Read

National prospective observational study of inpatient management of adults with epistaxis - a National Trainee Research Collaborative delivered investigation.

Rhinology 2019 Jan 5. Epub 2019 Jan 5.

Department of Otolaryngology, King's College, London, United Kingdom.

Background: There is a paucity of high-quality evidence relating to the management of epistaxis severe enough to require admission to a hospital. Previous studies of interventions for epistaxis have suffered from small sample sizes. They lacked the power to allow analysis of the effect of an intervention on epistaxis control that is independent of the condition severity or additional interventions given. Read More

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http://dx.doi.org/10.4193/Rhin18.239DOI Listing
January 2019
4 Reads

The sinonasal mycobiota in chronic rhinosinusitis and control patients.

Rhinology 2019 Jan 5. Epub 2019 Jan 5.

School of Medicine, The University of Auckland, Auckland, New Zealand.

Background: While bacterial associations with chronic rhinosinusitis (CRS) are increasingly well described, fewer studies have examined the fungal component of the sinonasal microbiota. Here we present a study of the sinonasal mycobiota in a cohort of 144 patients (106 patients with CRS and 38 controls).

Methodology: Fungal communities were characterised by analysis of mucosal swab samples of the left and right middle meatuses via ITS2 marker amplicon sequencing on the Illumina MiSeq platform. Read More

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http://dx.doi.org/10.4193/Rhin18.256DOI Listing
January 2019
13 Reads

Impact of cigarette smoke and IL-17A activation on asthmatic patients with chronic rhinosinusitis

Rhinology 2019 02;57(1):57-66

Department of Thoracic Medicine, Chang Gung Memorial Hospital and Medicine of College, Chang Gung University, Taoyuan, Taiwan.

Background: Cigarette smoke have adverse effects in the control of asthma and chronic rhinosinusitis (CRS). Interleukin (IL)-17A, the signature cytokine of helper T 17 cells and group 3 innate lymphoid cells (ILC3), has been reported to link with resistance to therapy in airway inflammation. This study aimed to investigate the impact of cigarette smoking and IL-17A activation on the clinical outcomes of asthmatic patients with chronic rhinosinusitis. Read More

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http://dx.doi.org/10.4193/Rhin18.131DOI Listing
February 2019
2 Reads

The prevalence and characteristics of local allergic rhinitis in Poland.

Rhinology 2018 Dec 17. Epub 2018 Dec 17.

Clinical Department of Otorhinolaryngology and Laryngological Oncology in Zabrze, Medical University of Silesia, Katowice, Poland.

Background: Local allergic rhinitis (LAR) is found in some patients with typical symptoms but who have negative skin prick tests and negative IgE to aeroallergens while presenting with positive nasal provocation tests for proper allergens. Little information about the clinical characteristics and prevalence of LAR has been published. The aim of this study was to determine the prevalence and characteristics of LAR in patients with symptoms of chronic rhinitis. Read More

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http://dx.doi.org/10.4193/Rhin18.137DOI Listing
December 2018
3 Reads

Eustachian Tube dysfunction in chronic rhinosinusitis: pre and post-operative results following endoscopic sinus surgery, a prospective study.

Rhinology 2019 Feb;57(1):73-77

ENT Department, Ipswich Hospital NHS Trust, Ipswich, United Kingdom.

Background: Prospective study investigating the incidence of concurrent Eustachian Tube dysfunction (ETD) in patients with CRS refractory to medical therapy, and the effect of Endoscopic Sinus Surgery (ESS) on ETD in this patient group.

Methods: Prospective study of 57 CRS patients. Outcome measures were SNOT-22 and ETDQ-7 questionnaires, tympanometry and Valsalva manoeuvre recorded pre-operatively and at 3 and 9 months post ESS. Read More

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http://dx.doi.org/10.4193/Rhin18.208DOI Listing
February 2019
2 Reads

Novel roles for nasal epithelium in the pathogenesis of chronic rhinosinusitis with nasal polyps.

Rhinology 2018 Dec 1. Epub 2018 Dec 1.

Otorhinolaryngology, Academic Medical Center, Amsterdam, the Netherlands.

Background: Airway epithelial cells have a well-accepted role in the regulation of local inflammatory processes in allergic and innate defence responses. However, their role the pathophysiology of chronic rhinosinusitis with nasal polyps (CRSwNP) is unclear. The objective was to investigate whether potential differences in the mRNA expression profile of nasal epithelia from healthy individuals and from CRSwNP patients would shed new light on disease mechanisms. Read More

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http://dx.doi.org/10.4193/Rhin18.128DOI Listing
December 2018
4 Reads

Topographical distribution of trigeminal receptor expression in the nasal cavity.

Rhinology 2019 Apr;57(2):147-152

Smell and Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.

Background: Topographical differences in trigeminal receptor distribution of the nasal cavity has been investigated so far indirectly using various agonists to stimulate receptors in different locations. However, polymodal activation of trigeminal receptors poses difficulties in such investigation. The aim of our study was to examine the distribution of trigeminal receptor mRNA expression using quantitative PCR. Read More

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http://dx.doi.org/10.4193/Rhin18.181DOI Listing
April 2019
2 Reads

Similar survival outcome after endoscopic and open approaches for sinonasal mucosal melanoma.

Rhinology 2019 Apr;57(2):132-138

Department of Otorhinolaryngology â€" Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Background: To describe a cohort of sinonasal mucosal melanoma (SNMM) patients, and to assess if choice of surgical approach (open versus endoscopic) has impact on survival.

Methodology: Adequate data on clinical presentation, treatment, and recurrence pattern were available for 58 consecutive patients treated for SNMM at the Helsinki University Hospital (HUH) between 1983 and 2016.

Results: The 5-year disease-specific survival (DSS) was 27% and overall survival 25% for the whole cohort. Read More

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http://dx.doi.org/10.4193/Rhin18.123DOI Listing
April 2019
16 Reads

Clinical efficacy of intranasal drug delivery by nebulization in chronic rhinosinusitis: a systematic review.

Rhinology 2019 Apr;57(2):82-93

Service d’Oto-rhino-laryngologie, Cliniques universitaires Saint-Luc, Brussels, Belgium.

Background: Treatment of chronic rhinosinusitis (CRS) aims to treat the underlying inflammation or infection. Although the optimal modality of administration remains controversial, inhalation route is usually preferred. The aim of this systematic review was to summarize the efficacy of intranasal corticoisteroids or antibiotics delivery by nebulization on symptoms, histology, endoscopy scores, nasal obstruction, clinical outcomes and quality of life in CRS. Read More

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http://dx.doi.org/10.4193/Rhin18.010DOI Listing
April 2019
14 Reads

Lack of correlation between serum 25(OH)D level and endoscopy-based chronic rhinosinusitis in Korean adults.

Rhinology 2019 Apr;57(2):139-146

Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea.

Background: Several previous studies have shown that serum 25(OH)D deficiency is associated with increased risk of chronic rhinosinusitis (CRS) in adults and also correlated with disease severity. We aimed to investigate the correlation between serum 25(OH)D level and endoscopy-based CRS in adults using the Korean National Health and Nutrition Examination Survey.

Methods: The data were based on the Korean National Health and Nutrition Examination Survey from 2008 to 2011. Read More

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http://dx.doi.org/10.4193/Rhin18.110DOI Listing
April 2019
11 Reads

From prevention to optimal treatment in chronic rhinosinusitis.

Authors:
P W Hellings

Rhinology 2018 Dec;56(4):305-306

Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium, Euforea, Brussels, Belgium.

Prevention of chronic rhinosinusitis remains a true societal challenge, as prevention of this highly prevalent non-communicable disease will significantly reduce socio-economic costs and improve the overall well-being of the large group of affected individuals. In alignment with the health priorities of national governments, prevention and cost-effective health care should be embraced by the Rhinologic community. Read More

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http://dx.doi.org/10.4193/Rhin18.404DOI Listing
December 2018
17 Reads

Propofol sedation in Drug Induced Sedation Endoscopy without an anaesthesiologist â€" a study of safety and feasibility.

Rhinology 2019 Apr;57(2):125-131

Department of ORL, Head and Neck Surgery and Audiology, Copenhagen University Hospital, Copenhagen, Denmark.

Background: Propofol sedation in Drug Induced Sedation Endoscopy (DISE) of the upper airway of patients with obstructive sleep apnea (OSA) without the presence of anesthesiologist has not been done before. Propofol sedation is normally administered by an anesthesiologist. This is the first study of this new method. Read More

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http://dx.doi.org/10.4193/Rhin18.066DOI Listing
April 2019
10 Reads

Radiologic changes in the aging nasal cavity.

Rhinology 2019 Apr;57(2):117-124

Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, SC United States.

Background: With an aging population, it is important to understand age-related anatomic changes in the nasal cavity and cribriform plate (CP) that may have clinical implications.

Methodology: Computed tomography (CT) scans obtained for non-rhinologic conditions were divided into a young cohort (N=35, 18-34 years old) and an older adult cohort (N=32, 80-99 years old). Intranasal airspace volumes and bony anatomy of the CP were manually segmented using OsiriX software. Read More

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http://dx.doi.org/10.4193/Rhin18.096DOI Listing
April 2019
12 Reads

Fibrin tissue adhesive versus nasal packing in endoscopic nasal surgery: a systematic review and meta-analysis.

Rhinology 2019 Feb;57(1):21-31

Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom.

Background: It has been proposed that fibrin tissue adhesive (FTA) can act as an effective alternative to nasal packing in managing the postoperative symptoms of endoscopic nasal surgery.

Methodology: MEDLINE, Embase, Cochrane Library, The Cumulative Index to Nursing and Allied Health Literature and ClinicalTrials.gov were searched for randomised controlled trials comparing FTA with nasal packing in endoscopic nasal surgery. Read More

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http://dx.doi.org/10.4193/Rhin18.112DOI Listing
February 2019
2 Reads

Local specific Immunoglobulin E among patients with nonallergic rhinitis: a systematic review.

Rhinology 2019 Feb;57(1):10-20

Rhinology and Skull Base Research Group, St Vincents Centre for Applied Medical Research, University of New South Wales, Sydney, Australia; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.

Background: Allergen specific immunoglobulin can be present in the nasal mucosa of patients with non-allergic rhinitis (NAR). This condition is defined as local allergic rhinitis. However, the reported presence of nasal specific immunoglobulin E (nspIgE) among NAR is variable. Read More

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http://dx.doi.org/10.4193/Rhin18.074DOI Listing
February 2019
1 Read

Delivering better results for patients through core outcomes, measuring evidence and patient participation.

Authors:
W J Fokkens

Rhinology 2018 Sep;56(3):193-194

Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, The Netherlands.

Nasal obstruction is one of the most frequent and bothersome symptoms in rhinosinal disease. Although we are able to measure nasal airflow, the correlation between the feeling of nasal obstruction and objective measurements has been shown to be average at most. A significant proportion of the European population has a more or less deviated nasal septum and deviated septa have received a lot of attention from otorhinolaryngologists. Read More

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http://dx.doi.org/10.4193/Rhin18.403DOI Listing
September 2018
3 Reads

Responsiveness and minimal clinically important difference for the EQ-5D in chronic rhinosinusitis.

Rhinology 2019 Apr;57(2):110-116

Department of Otolaryngology, Harvard Medical School, Boston, MA, USA.

Background: The 5-dimensional EuroQol questionnaire (EQ-5D) is validated to measure general health-related quality of life (QOL). Our objective was to determine the responsiveness and minimal clinically important difference (MCID) of the EQ-5D health utility value (EQ-5D HUV) and visual analog scale (EQ-5D VAS) in chronic rhinosinusitis (CRS).

Methods: 203 adults undergoing medical management for CRS were prospectively recruited. Read More

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http://dx.doi.org/10.4193/Rhin18.122DOI Listing
April 2019
2 Reads

Entering a new era of Predictive Medicine in Rhinology.

Authors:
P W Hellings

Rhinology 2018 Jun;56(2):97-98

Clinical Division of Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium.

The June 2018 issue of Rhinology paves the way for real-life implementation of Precision Medicine in Rhinology, with Predictive Medicine in the center of attention. Physicians treating patients with rhinologic disorders might find it extremely interesting to find reports on predictors of success of medical or surgical interventions. Prediction of success of treatment is crucial to allow the patient become an active partner in the decision-making process of medical or surgical treatment. Read More

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http://www.rhinologyjournal.com/Abstract.php?id=1809
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http://dx.doi.org/10.4193/Rhin18.402DOI Listing
June 2018
16 Reads

Comparison of efficacy of fluticasone propionate versus clarithromycin for postoperative treatment of different phenotypic chronic rhinosinusitis: a randomized controlled trial.

Rhinology 2019 Apr;57(2):101-109

Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Background: Chronic rhinosinusitis (CRS) can be divided to CRS without nasal polyps (CRSsNP) and eosinophilic and non-eosinophilic CRS with nasal polyps (CRSwNP). There is little evidence on the efficacy of glucocorticoids and macrolides in different phenotypic patients. The aim of this study was to compare the benefit of glucocorticoids and macrolides following endoscopic sinus surgery (ESS) in different phenotypic CRS. Read More

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http://dx.doi.org/10.4193/Rhin17.226DOI Listing
April 2019
2 Reads

Primary surgical treatment of nasal vestibule cancer - therapeutic outcome and reconstructive strategies.

Rhinology 2018 Dec;56(4):393-399

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Heidelberg, Ruprecht-Karls-University Heidelberg, Germany.

Objective: The treatment strategy of squamous cell carcinoma of the nasal vestibule (SCCNV) is controversial. The objective of this study is to investigate the role of surgery, which is the preferred treatment option at our institution.

Design: This was a monocentric prospective study of patients that were diagnosed with SCCNV between 2005 and 2013. Read More

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http://dx.doi.org/10.4193/Rhin17.157DOI Listing
December 2018
2 Reads

Medication use in patients with chronic rhinosinusitis in Germany - a large retrospective patient-based study.

Rhinology 2019 Apr;57(2):94-100

Epidemiology, IQVIA, Frankfurt, Germany.

Background: The aim of the present study was to provide an insight into medical treatment practices among patients with chronic rhinosinusitis (CRS) in Germany. An investigation of ICD codes and ATC classes of CRS patients in general and otolaryngology offices in Germany should reveal the prevalent treatment behaviors of German physicians.

Methods: The present study used data from the Disease Analyzer database (IQVIA). Read More

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http://dx.doi.org/10.4193/Rhin18.055DOI Listing
April 2019
20 Reads

Olfactory training changes electrophysiological responses at the level of the olfactory epithelium.

Rhinology 2018 Dec;56(4):330-335

Smell and Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.

Background: Olfactory training (OT) has been shown to increase olfactory performance in healthy subjects and patients with post-traumatic or post-infectious olfactory loss. Morphological correlates such as olfactory bulb volume increase and gray matter changes suggest central changes in olfactory brain areas following olfactory exposure. Some evidence from animal studies indicates peripheral changes upon OT whereas no such data exist in humans. Read More

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http://dx.doi.org/10.4193/Rhin17.163DOI Listing
December 2018
1 Read

Rhinology future trends: 2017 EUFOREA debate on allergic rhinitis.

Rhinology 2019 Feb;57(1):49-56

Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK.

The 2nd Rhinology Future Debate, organized by EUFOREA (European Forum for Research and Education in Allergy and Airways diseases) was held in Brussels in December 2017. One of these debates addressed the position of MP-AzeFlu in allergic rhinitis (AR) treatment. The current article summarizes this debate; reviewing recent data, and exploring how this has been interpreted by experts and incorporated into AR management guidelines and a clinical decision support system (CDSS). Read More

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http://dx.doi.org/10.4193/Rhin18.076DOI Listing
February 2019
4 Reads

The clinical implications of computerised fluid dynamic modelling in rhinology.

Rhinology 2019 Feb;57(1):2-9

Department of Surgery, The University of Auckland, Auckland, New Zealand.

Background: The nose is a dynamic organ and is the first point of contact between inhaled air and mucosal surfaces. Within the nasal cavity, there are changes of air flow and pressure occurring during the respiratory cycle, as well as exchanges of heat and humidity, and important immune responses to inhaled antigens and allergens.

Methodology: This review is a summary for rhinologists covering what is known about airflow within the nose and sinuses and the impact of pathology and treatments on the physical environment of the nasal cavity. Read More

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http://dx.doi.org/10.4193/Rhin18.035DOI Listing
February 2019
17 Reads

Prevention of chronic rhinosinusitis.

Rhinology 2018 Dec;56(4):307-315

Department of Otorhinolaryngology, Head and Neck Surgery University Hospitals Leuven, Belgium.

Prevention of chronicity of disease and minimising its impact with individualized treatment is a fundamental tenet of precision medicine. A review of the literature has been undertaken to explore how this may apply to chronic rhinosinusitis (CRS). Prevention may be thought of across 3 main domains. Read More

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http://www.rhinologyjournal.com/Abstract.php?id=1825
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http://dx.doi.org/10.4193/Rhin17.027DOI Listing
December 2018
21 Reads

Quality of life after nasal cancer resection - surgical versus prosthetic rehabilitation.

Rhinology 2018 Dec;56(4):400-406

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Heidelberg, Ruprecht-Karls-University Heidelberg, Germany.

Background: Nose reconstruction following resection of nasal carcinomas is controversial. The objective of this study is to investigate the effect of surgical reconstruction versus prosthetic rehabilitation on patient quality of life (QOL).

Design: This was a monocentric prospective study of patients diagnosed with nasal carcinoma from 2003 to 2013. Read More

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http://dx.doi.org/10.4193/Rhin18.030DOI Listing
December 2018
2 Reads

Chitosan films promote formation of olfactory neurospheres and differentiation of olfactory receptor neurons.

Rhinology 2018 Dec;56(4):336-342

Department of Electrical Engineering, College of Electrical and Communication Engineering, Yuan Ze University, Taoyuan, Taiwan.

Background: Olfactory dysfunction significantly impairs the life quality of patients. Therefore, a model needs to be developed for anosmia. Chitosan is a biodegradable natural polysaccharide that has been widely studied for regenerative purposes in the nervous system. Read More

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http://dx.doi.org/10.4193/Rhin17.155DOI Listing
December 2018
2 Reads

Chronic rhinosinusitis exacerbations are differentially associated with lost productivity based on asthma status.

Rhinology 2018 Dec;56(4):323-329

Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.

Background: The frequency of chronic rhinosinusitis (CRS) exacerbations is an independent predictor of quality of life. The objective of this study was to evaluate if increased CRS exacerbations predict decreased productivity.

Methods: Cross-sectional study of adult CRS patients. Read More

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http://dx.doi.org/10.4193/Rhin18.033DOI Listing
December 2018
3 Reads

Modified nasal floor and inferior meatus flap for septal perforation repair. Extension and limits.

Rhinology 2018 Dec;56(4):386-392

Rhinology and Skull Base Unit, Department of Otorhinolaryngology, Hospital Clinic, Universitat de Barcelona, Spain.

Background: The nasal floor and inferior meatus (NFIM) flap represents an available option for the reconstruction of a septal perforation (SP). This study explores the feasibility of repairing SPs using a modified simple and extended (including inferior turbinate) NFIM flap.

Methods: An anatomic study was achieved in fresh frozen cadaveric specimens to measure the area and lengths of NFIM flap. Read More

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http://dx.doi.org/10.4193/Rhin18.036DOI Listing
December 2018
3 Reads

Histopathological features of antrochoanal polyps in Chinese patients.

Rhinology 2018 Dec;56(4):378-385

Department of Otolaryngology, National University of Singapore, National University Health System, Singapore, Singapore.

Background: The pathogenesis and etiology of antrochoanal polyps (ACP) are unclear. The aim of this study is to characterize the features of inflammatory cellular infiltration, the epithelial remodeling patterns and their associations to clinical parameters in ACP.

Methods: A detailed histological study employing classic immunohistochemistry was performed. Read More

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http://dx.doi.org/10.4193/Rhin18.057DOI Listing
December 2018
1 Read

Epidemiology of chronic rhinosinusitis in Bushehr, southwestern region of Iran: a GA2LEN study.

Rhinology 2019 Feb;57(1):43-48

Department of Immunology and Allergy, The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.

Background: Population-based studies using the European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS) criteria for the assessment of the chronic rhinosinusitis (CRS) prevalence play important roles in the development and promotion of public health policies.

Methods: A multistage, stratified cluster, random sampling method was used to select the study participants from individuals living in Bushehr, which is in the southwestern part of Iran. The standardized Global Allergy and Asthma European Network (GA2LEN) questionnaire was completed by 5,201 participants, and the CRS prevalence were compared among different groups of related factors using chi-squared tests. Read More

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http://dx.doi.org/10.4193/Rhin18.061DOI Listing
February 2019
2 Reads

Sinonasal inverted papilloma recurrence rates and evaluation of current staging systems.

Rhinology 2018 Dec;56(4):407-414

Division of Otolaryngology, University of British Columbia, St. Pauls Sinus Centre, Vancouver, British Columbia, Canada.

Background: Sinonasal inverted papillomas (SNIPs) are benign epithelial growths with high recurrence rates after surgical management. This study aims to evaluate SNIP recurrence rates after endoscopic surgery and to provide a comparison of published staging systems.

Methods: This chart review evaluated primary and revision SNIP cases from January 2008 to December 2016 at a tertiary sinus centre. Read More

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http://www.rhinologyjournal.com/Abstract.php?id=1822
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http://dx.doi.org/10.4193/Rhin18.039DOI Listing
December 2018
6 Reads