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Curr Med Mycol 2020 ;6(1):30-35

Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Background And Purpose: Organ transplant recipients are vulnerable to fungal infections. The aim of this study was to determine the prevalence of fungal colonization and infections among patients who underwent various transplantations and molecularly characterize the etiological agents.

Materials And Methods: This study was conducted on candidates for transplantation in Imam Khomeini Hospital, Tehran, Iran, from April 2017 to April 2018. Read More

Mycopathologia 2020 Jun 9;185(3):555-567. Epub 2020 May 9.

Department of Dermatology, The Affiliated Hospital, Guizhou Medical University, Beijing Road 4, Yunyan District, Guiyang, China.

Background: Lichtheimia species are emerging opportunistic fungal pathogens in the Mucorales, causing serious skin and respiratory infections in immunocompromised patients. Established agents are Lichtheimia corymbifera and L. ramosa, while L. Read More

J Hand Surg Am 2020 Mar 23. Epub 2020 Mar 23.

Department of Orthopedic Surgery, Columbia University Medical Center, New York, NY.

Mucormycosis is a relatively rare but extremely aggressive fungal infection that commonly affects patients who are compromised hosts. These infections typically come in various patterns: pulmonary, sinus, rhinocerebral, cerebral, cutaneous, or disseminated forms. Treatment usually consists of a combination of antifungal agents and surgical debridement, although morbidity and mortality are high. Read More

J Radiol Case Rep 2019 Oct 31;13(10):1-10. Epub 2019 Oct 31.

Department of Radiodiagnosis, B J Govt. Medical College & Sassoon General Hospitals, Pune, India.

Mucormycosis is a rare opportunistic fungal infection, often life-threatening. We report an unusual case of rhinocerebral mucormycosis in an immunocompetent patient. A 23-year-old male presented with headache, speech disturbance and hearing difficulty for 4 weeks. Read More

Br J Haematol 2020 Apr 29;189(2):339-350. Epub 2019 Dec 29.

The Rina Zaizov Division of Pediatric Hematology-Oncology, Schneider Children's Medical Center, Petah Tikva, Israel.

Mucormycosis has emerged as an increasingly important cause of morbidity and mortality in immunocompromised patients, but contemporary data in children are lacking. We conducted a nationwide multicentre study to investigate the characteristics of mucormycosis in children with haematological malignancies. The cohort included 39 children with mucormycosis: 25 of 1136 children (incidence 2·2%) with acute leukaemias prospectively enrolled in a centralized clinical registry in 2004-2017, and an additional 14 children with haematological malignancies identified by retrospective search of the databases of seven paediatric haematology centres. Read More

Clin Transplant 2020 Feb 9;34(2):e13774. Epub 2020 Jan 9.

Pulmonary Institute, Rabin Medical Center, Petach Tiqwa, Israel.

Background: Mucormycosis is a rare infection in lung transplant recipients (LTR). Our objective was to better define the clinical presentation and optimal management of this frequently lethal infection.

Methods: A systematic review of the literature was performed to identify all published cases of mucormycosis in LTR using PubMed/MEDLINE. Read More

Indian J Otolaryngol Head Neck Surg 2019 Nov 4;71(Suppl 3):1962-1971. Epub 2018 May 4.

Department of ENT, Shri Mahant Indiresh Hospital, Shri Guru Ram Rai Institute of Medical Sciences, Dehradun, Uttarakhand India.

Mucormycosis caused by one of the members of Mucoraceae family, is one of the most rapidly spreading and fatal fungal infection occurring mostly in Diabetic or Immunocompromised patients especially in developing countries. 26 patients suffering from sinonasal mucormycosis admitted in SGRRIM&HS, Dehradun from January 2013 to January 2017 are discussed. Diagnosis of mucormycosis was established on strong clinical suspicion with presence of grayish black crusting on nasal endoscopy which is confirmed by histopathology examination. Read More

Indian J Pathol Microbiol 2019 Oct-Dec;62(4):618-620

Department of Pathology, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.

Opportunistic fungal infections occur predominantly in immunocompromised (IC) patients. Mucormycosis has the highest mortality among fungal infections. The organism is ubiquitous in its presence. Read More

Rev Iberoam Micol 2019 Jul - Sep;36(3):160-164. Epub 2019 Sep 25.

Pediatric Infectious Diseases Department, Hospital Infantil de México Federico Gómez, Mexico.

Background: Mucormycosis is a fungal infection caused by species of the Mucorales order. These microorganisms are angioinvasive, with rapid disease progression and potentially lethal in its rhinocerebral form.

Case Report: We present the case of a 12-year-old female with trisomy 21, acute lymphoblastic leukemia and diabetes, with fever and neutropenia who developed rhinocerebral mucormicosis. Read More

Zhonghua Yan Ke Za Zhi 2019 Aug;55(8):629-633

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

Mucormycosis is a rare, rapidly progressive life threatening opportunistic fungal infection, with rhinocerebral mucormycosis being the most common type. Rhinocerebral mucormycosis usually presents symptoms similar to sinusitis and orbital cellulitis during its early stage,which often leads to a misdiagnosis at the very beginning,and progresses rapidly to endophthalmitis,blindness,sclera perforation, eyeball atrophy, and even gets the central nervous system involved, thus leading to death. Mucormycosis is particularly common in patients with poor glycemic control, ketoacidosis and immunosuppression. Read More

Neurosurg Focus 2019 08;47(2):E14

Departments of1Neurosurgery.

Objective: Intracranial fungal granuloma (IFG) remains an uncommon entity. The authors report a single-institute study of 90 cases of IFG, which is the largest study until now.

Methods: In this retrospective study, all cases of IFG surgically treated in the years 2001-2018 were included. Read More

Trauma Case Rep 2019 Oct 15;23:100221. Epub 2019 Jul 15.

Center for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.

Background: Mucormycosis is a rare but life-threatening infection, caused by fungi of the Mucorales order, which can be found in soil, rotting leaves or on animals. Through characteristic angioinvasive growth, infections with mucor spores can occur as a pulmonary, rhinocerebral or cutaneous form. Infections mainly affect immunosuppressed patients with a history of uncontrolled diabetes or haematological malignancies, among others. Read More

Clin Case Rep 2019 Jul 5;7(7):1382-1387. Epub 2019 Jun 5.

Unit of Otorhinolaryngology, Department of Adult and Development Age Human Pathology "Gaetano Barresi" University of Messina Messina Italy.

Rhinocerebral mucormycosis is a rapidly life-threatening disease caused by a fungal infection. Every diabetic patient with sinusitis symptoms, headache, and visual changes needs radiological approach and nasal endoscopy to rule out mucormycosis. The mortality rate is 50%-85%, despite an early diagnosis and a correct treatment. Read More

Rev Gastroenterol Peru 2019 Apr-Jun;39(2):193-196

Médico Patólogo. Servicio de Anatomía Patológica, Instituto de Salud del Niño. Lima, Perú.

Mucormycosis is a rare, usually fatal, opportunistic infection that mostly affects people with immune deficiency or associated pathologies. There are few reports of this disease in patients without the traditional risk factors, still unknown what could be the real predisposing causes involved. The forms of presentation are rhinocerebral, cutaneous, pulmonary, gastrointestinal and disseminated. Read More

Ann Maxillofac Surg 2019 Jan-Jun;9(1):192-196

Department of Oral and Maxillofacial Surgery, Saveetha Dental College, Chennai, Tamil Nadu, India.

Objective: The objective of this study was to prospectively analyze the effectiveness of a treatment protocol in patients diagnosed with rhinocerebral mucormycosis.

Materials And Methods: This series included ten patients who reported with suspicious clinical signs of mucormycosis. The diagnosis was established by histopathology, and computed tomography imaging was used to assess the extent of spread. Read More

J Endocr Soc 2019 Jul 6;3(7):1361-1366. Epub 2019 Jun 6.

Swiss Centre for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.

We describe two cases of hypertension and hypokalemia due to mineralocorticoid excess caused by posaconazole treatment of coccidioidomycosis and rhinocerebral mucormycosis infections, respectively. Clinical laboratory evaluations, including a comprehensive analysis of blood and urine steroid profiles, revealed low renin and aldosterone and indicated as the underlying mechanism primarily a block of 11-hydroxylase activity in patient 1, whereas patient 2 displayed weaker 11-hydroxylase but more pronounced 11-hydroxysteroid dehydrogenase 2 inhibition. The results show that both previously suggested mechanisms must be considered and emphasize significant interindividual differences in the contribution of each enzyme to the observed mineralocorticoid excess phenotype. Read More

Curr Med Mycol 2019 Mar;5(1):37-41

Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Background And Purpose: Rhinocerebral mucormycosis is a rare fatal fungal infection which is on a growing trend, particularly among immunocompromised patients. Immunosuppressive drugs, including corticosteroids and antimetabolites, increase the risk of this infection. Herein, we reported the case of fulminant rhinocerebral mucormycosis in a patient with ulcerative colitis receiving azathioprine and corticosteroid. Read More

Front Neurol 2019 26;10:264. Epub 2019 Mar 26.

Department of Neurosurgery, Arrowhead Regional Medical Center, Colton, CA, United States.

Mucormycosis is a rapidly progressive, angioinvasive fungal infection that has a predilection for the paranasal sinuses and adjacent mucosa. Rhinocerebral mucormycosis (RCM) is the most common form and is known to invade the skull base and its associated blood vessels-leading to mycotic aneurysms, ischemic infarcts, and intracerebral hemorrhage. There are documented cases of mechanical thrombectomy in ischemic stroke due to RCM, however, there are no known cases that were diagnosed primarily by histological and pathological analysis of the embolus. Read More

Indian J Pathol Microbiol 2019 Apr-Jun;62(2):332-334

Department of Pathology, Columbia Asia Hospital, Hebbal, Bengaluru, Karnataka, India.

Mucormycosis is caused by fungi of the order Mucorales and class Zygomycetes. It is a rare opportunistic infection frequently associated with immunocompromised status. It can be disseminated disease or localized, which includes rhinocerebral, pulomonary, cutaneous, and gastrointestinal mucormycosis. Read More

J Oral Maxillofac Pathol 2019 Feb;23(Suppl 1):122-125

Department of Oral Pathology and Microbiology, Mamata Dental College, Khammam, Telangana, India.

Mucormycosis is an opportunistic fulminant fungal infection which mainly affects the immunocompromised individuals. It begins in the nose and paranasal sinuses due to the inhalation of fungal spores. The common predisposing factors include diabetes mellitus and immunosuppression. Read More

J Oral Maxillofac Surg 2019 Jun 18;77(6):1209.e1-1209.e12. Epub 2019 Feb 18.

Head, Department of Oral and Maxillofacial Surgery, Hebrew University-Hadassah, Jerusalem, Israel.

Purpose: Mucormycosis is a rare opportunistic and aggressive deep fungal infection that predominantly affects immunocompromised patients, and its mortality rate has been reported as up to 80%. Typing of the infection is based mainly on clinical and anatomic presentations, with the most common being the rhinocerebral type.

Materials And Methods: This report presents 3 patients with cancer who had successful treatment of mandibular mucormycosis. Read More

BMC Infect Dis 2019 Feb 22;19(1):184. Epub 2019 Feb 22.

Alberta Health Services, Calgary, Canada.

Background: Mucormycosis is a group of rare but life threatening angioinvasive infections caused by fungi of the order Mucorales that often occurs in immunocompromised patients and individuals with poorly controlled diabetes. Rhinocerebral mucormycosis can mimic sinusitis but can rapidly progress to deeper disease and cause facial necrosis. Facial vascular thrombosis is a rare complication of mucormycosis and can confound diagnosis of the disease. Read More

Fed Pract 2018 Jan;35(1):32-36

and are Internal Medicine Residents at Scott and White Memorial Hospital. and are Physicians at the Central Texas Veterans Health Care System; all in Temple, Texas.

Prompt diagnosis of a patient presenting with rhinocerebral, pulmonary, gastrointestinal, and central nervous system manifestations is critical for treatment of this potentially fatal fungal infection. Read More

Medicine (Baltimore) 2018 Dec;97(51):e13290

Department of Otolaryngology-Head and Neck Surgery.

Rationale: Mucormycosis is a rare fungal infection which mainly develops in compromised hosts and the associated mortality rate is high.

Patient Concerns: We report a case of mucormycosis in a 59-year-old woman following routine endoscopic sinus surgery. The patient had a history of diabetes mellitus (DM) and bronchial asthma. Read More

Rev Iberoam Micol 2018 Oct - Dec;35(4):217-221. Epub 2018 Nov 22.

Unidad de Enfermedades Infecciosas, Hospital Universitario y Politécnico La Fe, Valencia, España. Electronic address:

Infections due to zygomycetes, caused by mucorales and entomophthorales, are characterized by angioinvasion and invasion of neighboring organs or structures. Mucorales most commonly cause rhinocerebral, pulmonary, cutaneous or disseminated infection and its spread is favored by several diseases (such as diabetes or chronic kidney disease) and risk factors (neutropenia, immunosuppression, iron overload). They have a high mortality rate, and the key to success in their treatment are early diagnosis, prompt administration of antifungal treatment, and extensive surgical debridement. Read More

Med Mycol Case Rep 2018 Dec 21;22:69-73. Epub 2018 Sep 21.

Hamad Medical Corporation, Al-Sadd, Doha 3050, Qatar.

Immunocompromised status is associated with invasive fungal infections including mucormycosis. These infections are challenging to treat and associated with high overall mortality. Here we report a fatal case of invasive mucormycosis in a cirrhotic, diabetic patient. Read More

Mycoses 2018 Dec 28;61(12):909-915. Epub 2018 Aug 28.

Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Background: Accurate diagnosis of mucormycosis, a life-threatening fungal infection, remains a challenge for physicians.

Objectives: To identify the causative Mucorales in fresh clinical samples and formalin-fixed paraffin-embedded (FFPE) samples of patients with proven mucormycosis by molecular method.

Patients/methods: Fresh clinical samples of patients with proven mucormycosis according to the EORTC/MSG criteria admitted between 2015 and 2017 and histopathologically proven FFPE archives collected during 2004-2007 and 2015-2017 from Mazandaran University-affiliated hospitals of northern Iran were included. Read More

Mycoses 2018 Oct 2;61(10):764-769. Epub 2018 Jul 2.

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.

Inadequate data are available on the global epidemiology of mucormycosis, mainly derived from the evaluation of specific population groups. Rhinocerebral mucormycosis is an invading and fatal mycosis, particularly among diabetic patients. In the present study, patients hospitalised in Imam Reza Hospital in Tabriz, from 2007 to 2017, were evaluated. Read More

Laryngorhinootologie 2018 Aug 16;97(8):550-554. Epub 2018 May 16.

Universitätsklinikum Magdeburg HNO.

Mucormycosis is a rare but serious type of fungal infection, which can progress rapidly especially in immunsupressed patients.We report about a 47 year old female patient with ptosis on the left eye. The ophthalmological report offered no further pathologic findings. Read More

Tunis Med 2017 May;95(5):378-380

Mucormycosis is a rare and acute fungal infection which is frequently lethal, usually observed in non-controlled diabetic patients. The infection usually begins in the nose but it can invade the lung, the digestive tract, and the skin. Rhinocerebral mucormycosis accounts for 40 to 49% of mucormycosis cases. Read More

J Oral Maxillofac Pathol 2018 Jan;22(Suppl 1):S112-S116

Department of Oral Pathology and Microbiology, V S Dental College and Hospital, Bengaluru, Karnataka, India.

Mucormycosis or zygomycosis, also called phycomycosis, is an uncommon, invasive, potentially lethal and an aggressive fungal infection of the order that usually affects patients with alteration of their immunological system. From its initial description (Paltauf, 1885), this entity still has a high mortality. Imaging techniques are not usually diagnostic, and cultures are not totally reliable. Read More

Antimicrob Agents Chemother 2018 05 26;62(5). Epub 2018 Apr 26.

Department of Hematology and Medical Oncology, University Medicine Göttingen (UMG), Göttingen, Germany

Asian Cardiovasc Thorac Ann 2018 Mar 15;26(3):242-244. Epub 2018 Feb 15.

3 Department of Pathology, 123647 Kahramanmaras Sutcu Imam University , Faculty of Medicine, Kahramanmaras, Turkey.

Mucormycosis is an opportunistic fungal infection that can infect different regions of the body. This entity may present in rhinocerebral, pulmonary, cutaneous, and disseminated forms. Although pulmonary mucormycosis is usually seen as an invasive parenchymal consolidation or cavitation, it may rarely present as an endobronchial mass. Read More

BMJ Case Rep 2018 Feb 8;2018. Epub 2018 Feb 8.

Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India.

Mucormycosis, a rare opportunistic infection seen in immunocompromised hosts, is caused by fungi of Mucorales family. It may be confined to the organs, such as rhinocerebral and pulmonary mucormycosis, or may cause disseminated infection. A 14-year-old boy presented to our clinic with fever and left upper quadrant abdominal pain, and on evaluation was found to have pancytopaenia, and imaging revealed ill-defined splenic collection with thrombus in the splenic vein. Read More

J Assoc Physicians India 2017 12;65(12):103-104

Chairman, Institute of Digestive disease & Hepatobiliary Sciences, Medanta-The Medicity, Gurgaon, Haryana.

Mucormycosis is a rare, opportunistic fungal infection that occurs almost exclusively in immunocompromised hosts such as patients with diabetes mellitus, leukemia, lymphoma, renal disease, septicemia, burns, malnutrition, and following long-term treatment with steroids and antibiotics. Based on the clinical presentation and involvement, mucormycosis is classified as six major forms, namely, rhinocerebral, pulmonary, cutaneous, gastrointestinal (GI), disseminated and miscellaneous, with rhinocerebral and pulmonary being the common forms. GI mucormycosis is rare, accounting for only 7% of all cases; however, the mortality rate is as high as 85%. Read More

J Pediatr Hematol Oncol 2018 10;40(7):e461-e463

Departments of Pediatrics.

Rhinocerebral mucormycosis (RCM) can lead to internal carotid artery thrombosis. Here, we report the first case of RCM with temporal artery thrombosis following HLA-haploidentical stem cell transplantation in an adolescent presenting with low-grade fever, right mandibular pain, and right jaw claudication. This case suggests that RCM can cause temporal artery thrombosis and should be considered as a differential diagnosis in severely immunocompromised patients with maxillary sinusitis presenting with jaw claudication. Read More

Pediatr Infect Dis J 2018 06;37(6):555-558

Rady Children's Hospital - San Diego, California.

A 17-year-old girl developed invasive rhinocerebral mucormycosis during intensive re-induction chemotherapy for relapsed pre-B acute lymphoblastic leukemia. Due to the high case fatality rate for invasive mucormycosis in profoundly immunosuppressed patients, an aggressive treatment regimen was pursued. In addition to the standard of care treatments with intravenous amphotericin and aggressive surgical debridements, she received intraventricular amphotericin to the brain via an Ommaya reservoir, hyperbaric oxygen treatments, filgrastim, intravenous immunoglobulin and antifungal in vitro synergy testing to allow for more targeted antifungal therapy with the addition of micafungin. Read More

Med Mycol Case Rep 2018 Mar 1;19:13-17. Epub 2017 Sep 1.

Pneumology Department, Hôpital Haut-Lévêque, CHU de Bordeaux, avenue de Magellan, 33604 Pessac, France.

Mucormycosis is a rare and life-threatening fungal infection of the Mucorales order occurring mainly in immunosuppressed patients. The most common forms are rhinocerebral but pulmonary or disseminated forms may occur. We report the case of a 61-year-old patient in whom pulmonary mucormycosis was diagnosed during his first-ever episode of diabetic ketoacidosis. Read More

J Mycol Med 2017 Dec 7;27(4):586-588. Epub 2017 Nov 7.

Department of Dermatology, the Forth Hospital of Hebei Medical University, PR China.

Mucormycosis is a rare life-threatening opportunistic infection caused by fungi of the order Mucorales. We report a case of rhinocerebral mucormycosis caused by Rhizopus arrhizus var. tonkinensis, the first formally reported case in the literature. Read More

J Infect Public Health 2018 May - Jun;11(3):301-303. Epub 2017 Nov 6.

Department of Otorhinolaryngology, Royal Medical Services, Bahrain Defence Force Hospital, Bahrain. Electronic address:

The purpose of presenting this case is to report a fatal case of rhinocerebral mucormycosis post-dental extraction in a patient with uncontrolled diabetes mellitus. Several cases of rhinocerebral mucormycosis have been reported, but mucocutaneous mucormycosis has not been commonly reported to be a part of polymicrobial wound infections at multifocal sites. To the best of author's knowledge, this is the second case of polymicrobial rhinocerebral infection involving mucormycosis. Read More

Plast Surg (Oakv) 2017 Aug 28;25(3):211-217. Epub 2017 Jun 28.

Department of Plastic Surgery, McMaster University, Hamilton, Ontario, Canada.

Rhinocerebral mucormycosis is an acute, rapidly fatal, fungal infection, classically involving the nasal mucosa and paranasal sinuses. It is an aggressive, opportunistic infection that frequently progresses to involve the orbit and cerebrum. Cerebral extension in immunocompromised patients is almost universally fatal. Read More

Int J Appl Basic Med Res 2017 Jul-Sep;7(3):202-204

Balaji Medicenter, Panchkula, India.

Mucormycosis is a rare potentially fatal opportunistic fungal infection that affects human beings. Normally, a healthy is immune to such infections but there are some risk factors which predispose a person to mucormycosis, of which malnutrition and diabetes mellitus are the most common risk factors. India is the most commonly affected country by mucormycosis because of high proportion people with low socioeconomic status and diabetes mellitus. Read More

Mycoses 2017 Dec 6;60(12):836-841. Epub 2017 Sep 6.

Division of Haematology-Oncology, Department of Internal Medicine, Konkuk University Medical Centre, Konkuk University School of Medicine, Seoul, Korea.

Mucormycosis is an aggressive and life-threatening opportunistic fungal infection, which predominantly affects immunocompromised patients. It typically manifests in rhinocerebral, pulmonary or disseminated forms in patients with immunosuppressive conditions. Mucormycosis limited to the oral cavity is rare, and to the best of our knowledge only seven cases have previously been reported in English literature. Read More

BMJ Case Rep 2017 Aug 7;2017. Epub 2017 Aug 7.

Intensive Care Unit, Hospital San Javier, Guadalajara, Jalisco, Mexico.

We present the case of a 28-year-old man with a long-standing history of cocaine abuse and Child-Pugh class C alcoholic liver cirrhosis who developed severe lower respiratory tract infection complicated with septic shock and multiple organ dysfunction. He was managed in the intensive care unit. On the eighth day after admission, he developed a nose discolouration, which was initially thought to be associated with high-dose vasopressors. Read More

Ann Maxillofac Surg 2017 Jan-Jun;7(1):120-123

Department of Internal Medicine, Armed Forces Medical College, Pune, Maharashtra, India.

Mucormycosis of the frontal sinus are rarely seen in day to day clinical practice. Although this fungus is commonly found in the environment, the disease is usually prevented by the immune system and is hence rare. Well-recognized risk factors for the disease include diabetes mellitus, leukemia, aplastic anemia, myelodysplastic syndrome, blood dyscrasias, and immunosuppressive therapy in organ transplantation, renal disease, sepsis, and severe burns. Read More

Mycopathologia 2017 Oct 21;182(9-10):933-935. Epub 2017 Jun 21.

Research Unit, Hospital La Inmaculada, Huércal-Overa, Almería, Spain.

Mucormycosis is an unusual fungal infection that usually affects immunosuppressed patients. Small outbreaks of mucormycosis have been previously reported. We present two clinical cases of fatal rhinocerebral mucormycosis with a close temporal relationship between them and a possible nosocomial transmission: case 1 was a 75-year-old male with diabetes and COPD, treated with antibiotics and systemic corticosteroids, who developed rhinocerebral mucormycosis. Read More

BMJ Case Rep 2017 May 22;2017. Epub 2017 May 22.

Pediatric Hematology-Oncology, University of California, San Diego, California, USA.

A 17-year-old female with recently relapsed acute lymphoblastic leukaemia and a treatment course complicated by rhinocerebral mucormycosis infection developed severe peripheral neuropathy during the treatment for mucormycosis infection. This was felt to be a medication side effect. Her peripheral neuropathy was refractory to many well-established treatments, but ultimately responded dramatically and consistently to a novel therapy, topical doxepin cream (5%). Read More

Pan Afr Med J 2017;26:143. Epub 2017 Mar 14.

Department of Otorhinolaryngology-Head and Neck Surgery Habib Bourguiba University Hospital, Sfax, Tunisia.

Eur Heart J Suppl 2016 Apr 29;18(Suppl E):E19-E21. Epub 2016 Apr 29.

IRCCS Policlinico San Donato, via Morandi, 30, 20097 San Donato Milanese, Italy.

Mucormycosis is an angioinvasive infection caused by ubiquitous filamentous fungi of the order Mucorales. We describe a case of rhinocerebral mucormycosis presented in a paediatric patient after cardiac surgery correction of a complete atrioventricular canal defect. The rhinocerebral form of mucormycosis in our patient presented as an important epistaxis that needed immediate intubation due to blood inhalation. Read More