5,608 results match your criteria Rheumatology International[Journal]


Age dependent ultrasound B-mode findings of the elbow joint in healthy children and adolescents.

Rheumatol Int 2019 Apr 20. Epub 2019 Apr 20.

Department of Pediatrics, Asklepios Hospital Weißenfels, Naumburger Strasse 76, 06667, Weissenfels, Germany.

Due to maturation of joints, various changes take place, not only in the field of paediatric rheumatology but also in paediatric orthopaedics musculoskeletal ultrasound plays an important role in both the diagnosis and the follow-up of diseases in this field. To differentiate between physiological and pathological findings, the knowledge of reference values of joint structures is indispensable. The objective was to define B-mode ultrasound age- and sex-related reference values for the elbow joint in healthy children and adolescents during maturation. Read More

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http://dx.doi.org/10.1007/s00296-018-4233-8DOI Listing
April 2019
1 Read

Use of high-resolution vessel wall magnetic resonance imaging in the diagnosis of temporal arteritis.

Rheumatol Int 2019 Apr 16. Epub 2019 Apr 16.

Clínica de Diagnóstico Por Imagem (CDPI), Avenida das Américas, 4666, 302A, 303, 307, 325, 326, Barra da Tijuca, Rio de Janeiro, RJ, 2640-102, Brazil.

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http://dx.doi.org/10.1007/s00296-019-04305-9DOI Listing
April 2019
1 Read

Discordance between doctor and patient assessments and non-adherence to subcutaneous biological drugs.

Rheumatol Int 2019 Apr 16. Epub 2019 Apr 16.

Medical Affairs, Merck Sharp & Dohme S.A, Madrid, Spain.

To estimate the agreement level between patient and physician assessment of disease activity and to explore whether agreement is associated with adherence to subcutaneous (SC) biological drugs in rheumatoid arthritis (RA). Cross-sectional study of RA patients who had been prescribed a SC biological drug in the past 12-18 months was performed. Patients and physicians global disease activity on visual analogue scale (VAS) were collected. Read More

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http://dx.doi.org/10.1007/s00296-019-04304-wDOI Listing
April 2019
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Successful arthroscopic treatment of refractory and complicated popliteal cyst associated with rheumatoid arthritis in combination with osteoarthritis: case series and literature review.

Rheumatol Int 2019 Apr 11. Epub 2019 Apr 11.

Division of Rheumatology, Department of Internal Medicine, Hanyang University Guri Hospital, 153, Gyeongchunro, Guri, Gyeonggi-do, 11923, South Korea.

Although popliteal cysts are most frequently identified in patients with osteoarthritis (OA), they may occur in patients with rheumatoid arthritis (RA), in which serious complicated cases such as cyst rupture can be developed. The objective of this study was to report four patients with RA (six knees) in combination with OA with a brief review of literature of previous similar published cases. This is a retrospective review of case records of patients with refractory and/or complicated popliteal cysts, who have successfully treated with arthroscopic intervention. Read More

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http://dx.doi.org/10.1007/s00296-019-04278-9DOI Listing
April 2019
1 Read

Adalimumab in the treatment of pediatric Behçet's disease: case-based review.

Rheumatol Int 2019 Apr 11. Epub 2019 Apr 11.

Department of Pediatric Rheumatology, National Research Center of Mother and Child Health, University Medical Center, Astana, Kazakhstan.

Behçet's disease (BD) is a systemic vasculitis affecting prominently the veins, which is usually diagnosed in adulthood, but can occur in children younger than 16 years in about 4-26% of cases. The therapy is based on several immune-suppressive drugs; in case of inadequate control and/or complications, the biologic therapy with anti-TNF drugs has been successfully used in adults. Here, we reported one pediatric case of BD with systemic (persistent/recurrent high fever), skin and mucosal manifestations (recurrent aphthous stomatitis, anal/penile ulcers, erythema nodosum and papulo-pustules), that were unresponsive to the conventional treatment with steroids and colchicine; however, he was successfully treated with adalimumab. Read More

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http://dx.doi.org/10.1007/s00296-019-04300-0DOI Listing
April 2019
2 Reads

Correction to: Systemic vasculitis involving the breast: a case report and literature review.

Rheumatol Int 2019 Apr 10. Epub 2019 Apr 10.

Department of Rheumatology and Immunology, Peking University Third Hospital, No. 49, North Garden Road, Beijing, 100191, China.

The article "Systemic vasculitis involving the breast: a case report and literature review" written by Jinxia Zhao, was originally published electronically on the publisher's internet portal (currently SpringerLink) on March 14, 2019 with open access. With the author(s) decision to step back from Open Choice, the copyright of the article changed to ©Springer-Verlag GmbH Germany, part of Springer Nature 2019 and the article is forthwith distributed under the terms of copyright.The original article has been corrected. Read More

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http://dx.doi.org/10.1007/s00296-019-04294-9DOI Listing

Clinical use of anti-DFS70 autoantibodies.

Rheumatol Int 2019 Apr 10. Epub 2019 Apr 10.

Department of Laboratory Medicine, KyungHee University Hospital at Gangdong, Seoul, South Korea.

The dense fine speckled (DFS) nuclear pattern is one of the most common indirect immunofluorescence (IIF) patterns detected during routine anti-nuclear antibody (ANA) screening. There is a negative association between anti-DFS70 status and systemic autoimmune rheumatic disease (SARD), especially in the absence of concomitant SARD-specific autoantibodies. The purpose of this study was to determine the need for confirming anti-DFS70 status when a DFS pattern is observed in IIF-ANA. Read More

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http://dx.doi.org/10.1007/s00296-019-04299-4DOI Listing

Evaluation of serum fibroblast growth factor-23 in patients with axial spondyloarthritis and its association with sclerostin, inflammation, and spinal damage.

Rheumatol Int 2019 Apr 9. Epub 2019 Apr 9.

Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, Izmir Katip Celebi University, Karabaglar, 35360, Izmir, Turkey.

The mechanisms underlying new bone formation in individuals with axial spondyloarthritis (axSpA) remain unclear; however, low levels of sclerostin (SOST) may be associated with development of syndesmophytes in those with ankylosing spondylitis (AS). Expression of fibroblast growth factor-23 (FGF-23), another osteocyte factor, is high in those with osteoporosis and chronic renal failure, but levels in those with axSpA are unknown. To evaluate serum FGF-23 and SOST levels in axSpA patients, and to assess their relationship with inflammation and structural damage. Read More

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http://dx.doi.org/10.1007/s00296-019-04298-5DOI Listing
April 2019
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Leveraging Google Trends to investigate the global public interest in rheumatoid arthritis.

Rheumatol Int 2019 Apr 6. Epub 2019 Apr 6.

Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, China.

This study aims to investigate the global public interest in rheumatoid arthritis by evaluating search term popularity changes of the disease over a decade. Google Trends was applied to retrieve search popularity scores for the term 'rheumatoid arthritis' between January 2004 and December 2017, utilizing the category of "health". Overall, relative searches volume for rheumatoid arthritis steadily decreased from January 2004 to December 2010, and then slowly rose from January 2011 to December 2017. Read More

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http://dx.doi.org/10.1007/s00296-019-04297-6DOI Listing
April 2019
1 Read

Secretory factors produced by adipose mesenchymal stem cells downregulate Th17 and increase Treg cells in peripheral blood mononuclear cells from rheumatoid arthritis patients.

Rheumatol Int 2019 Apr 3. Epub 2019 Apr 3.

Laboratory of Clinical Immunology, Department of Clinical Immunology, University Hospital "St. Ivan Rilski"-Sofia, Medical University of Sofia, Sofia, Bulgaria.

We aimed to assess the immunoregulatory effects of secretory factors produced by adipose tissue-derived MSC (AT-MSC) on Th17 and Treg subsets from patients with rheumatoid arthritis (RA). 17 patients with active disease matching the ACR/EULAR 2010 criteria for RA were included. Patients' peripheral blood mononuclear cells (PBMC) were cultured in AT-MSC-conditioned medium (AT-MSCcm) and in control medium. Read More

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http://dx.doi.org/10.1007/s00296-019-04296-7DOI Listing
April 2019
1 Read

High serum hepcidin is associated with the occurrence of anemia in anti-myeloperoxidase antibody-associated vasculitis with normal kidney function: a cross-sectional study.

Rheumatol Int 2019 Mar 29. Epub 2019 Mar 29.

Department of Nephrology, Tianjin Medical University General Hospital, No. 154 Anshan Road, Heping District, Tianjin, 300052, China.

The etiology of anemia in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) has not been elucidated. In this cross-sectional study, we tried to investigate the relationship between serum hepcidin and anemia in myeloperoxidase (MPO)-ANCA-AAV. Data of 64 newly diagnosed AAV patients who did not have kidney dysfunction or hemorrhage were analyzed. Read More

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http://dx.doi.org/10.1007/s00296-019-04292-xDOI Listing

Pain and gastrointestinal dysfunction are significant associations with psychiatric disorders in patients with Ehlers-Danlos syndrome and hypermobility spectrum disorders: a retrospective study.

Rheumatol Int 2019 Mar 28. Epub 2019 Mar 28.

Fred A. Litwin Family Centre in Genetic Medicine, University Health Network and Mount Sinai Hospital, 60 Murray Street, Box 34, 3rd Floor, Room 400, Toronto, ON, M5T 3L9, Canada.

In this retrospective study, we investigate the frequency and types of psychiatric disorders and their relationship to systemic manifestations in a cohort of 391 Ehlers-Danlos syndromes (EDS) and hypermobility spectrum disorder (HSD) patients based on the current 2017 International Classification of EDS diagnostic criteria. A detailed, systematic retrospective chart review was undertaken for patients assessed for HSD or EDS at two Canadian health centres. Patients were diagnosed according to the Villefranche criteria and reclassified for this study according to the 2017 International Classification of EDS. Read More

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http://dx.doi.org/10.1007/s00296-019-04293-wDOI Listing
March 2019
1 Read

Tolerability and safety of long-term rituximab treatment in systemic inflammatory and autoimmune diseases.

Rheumatol Int 2019 Mar 28. Epub 2019 Mar 28.

Clinical Immunology Unit, Stavanger University Hospital, Stavanger, Norway.

Rituximab, an anti-CD20 monoclonal antibody causing selective B-cell depletion, is used for various systemic inflammatory and autoimmune diseases (SIADs). Long-term safety data on rituximab are limited. The objectives of this study were to evaluate the long-term safety and tolerability of rituximab treatment for SIADs. Read More

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http://dx.doi.org/10.1007/s00296-019-04272-1DOI Listing
March 2019
1 Read

Rheumatology in Poland.

Rheumatol Int 2019 Mar 28. Epub 2019 Mar 28.

National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.

The aim of this article is to present the current state of rheumatology in Poland, including the scientific and clinical activity and essential aspects of Polish rheumatic patients' treatment. PubMed, Scopus and Web of Science databases were searched for main keywords: "rheumat*" and affiliation with Poland. Statistical data were obtained from the Central Statistical Office, the National Health Fund and the Polish Chamber of Physicians and Dentists, while the public information from the Polish Society for Rheumatology, the Ministry of Health and the Ministry of Science and Higher Education. Read More

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http://dx.doi.org/10.1007/s00296-019-04287-8DOI Listing

Real-world prevalence and incidence of lower back pain in Germany.

Authors:
Karel Kostev

Rheumatol Int 2019 Mar 27. Epub 2019 Mar 27.

Epidemiology, IQVIA, Unterschweinstiege 2-14, 60549, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s00296-019-04295-8DOI Listing

Evidence synthesis of types and intensity of therapeutic land-based exercises to reduce pain in individuals with knee osteoarthritis.

Rheumatol Int 2019 Mar 26. Epub 2019 Mar 26.

Physiotherapy Program, School of Rehabilitation, UNIFESP, São Paulo, Brazil.

The objective of this study is to construct an evidence synthesis to identify the types of land-based exercises most investigated in the current literature, the intervention duration, frequency of the programs and the exercises which are most frequently implemented. A search was performed on the reference list of included and excluded studies of one systematic review, on land-based exercises for knee osteoarthritis and, an updated search of The Cochrane Library, Embase, CINAHL and PEDro was completed. Two authors independently selected the studies and a third author was consulted for an additional opinion. Read More

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http://dx.doi.org/10.1007/s00296-019-04289-6DOI Listing

Parameters of arterial stiffness in patients with Behçet's disease and their relationship with disease duration.

Rheumatol Int 2019 Mar 26. Epub 2019 Mar 26.

Department of Internal Medicine, Saglik Bilimleri University, Bursa Yuksek Ihtisas Education and Research Hospital, Bursa, Turkey.

The results of investigations of arterial stiffness in Behçet's disease (BD) are contradictory and the reason for this contradictory situation is not clear. The lack of studies in homogenous groups according to the duration of the disease may be the cause of conflicting results. To compare arterial stiffness by assessing pulse wave velocity (PWV) and augmentation index (AIx) measurements in healthy controls (HC) and patients diagnosed with BD with short and long disease duration. Read More

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http://dx.doi.org/10.1007/s00296-019-04291-yDOI Listing

Modifiable risk factors in knee osteoarthritis: treatment implications.

Rheumatol Int 2019 Mar 25. Epub 2019 Mar 25.

Clinic of Rheumatology, University Hospital "St. Ivan Rilski", Medical University-Sofia, Sofia, Bulgaria.

Optimal management of knee osteoarthritis (KOA) should include, where possible, modification of risk factors through targeted interventions. The objectives of the present narrative review were to identify, summarize, and cluster all the potentially modifiable risk factors that influence the course of KOA, and discuss their susceptibility to alteration via personal, clinical, and public strategy. For this purpose, Pubmed and Scopus databases were queried using the terms "knee osteoarthritis", "risk factors" and "improvement". Read More

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http://link.springer.com/10.1007/s00296-019-04290-z
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http://dx.doi.org/10.1007/s00296-019-04290-zDOI Listing
March 2019
10 Reads

Retrospective study of the course, treatment and long-term follow-up of Kawasaki disease: a single-center experience from Poland.

Rheumatol Int 2019 Mar 22. Epub 2019 Mar 22.

Department of Pediatric Cardiology and Rheumatology, Medical University of Lodz, Sporna 36/50 street, 91-738, Lodz, Poland.

Kawasaki disease (KD) is an acute, self-limited, systemic vasculitis and the most common cause of acquired coronary artery disease in pediatric population in the developed countries. It occurs mostly in Asian countries; however, due to better access to diagnostic and imaging tests, it is more frequently diagnosed among pediatric patients in Poland. The aim of this study was to describe the clinical course with special interest in cardiac involvement, treatment and follow-up of Polish patients with KD. Read More

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http://dx.doi.org/10.1007/s00296-019-04286-9DOI Listing
March 2019
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The impact of physical activity on serum levels of inflammatory markers in rheumatoid arthritis: a systematic literature review.

Rheumatol Int 2019 Mar 21. Epub 2019 Mar 21.

Department of Orthopaedics, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.

This review aims to determine the specific effects of PA on systemic levels of interleukins and inflammatory markers. A systematic literature search was conducted in three computerized bibliographic databases (Medline, Embase, CENTRAL) to identify randomized controlled trials and matched case studies. Applied key words were: RA and PA including the terms exercise, exercise therapy, gymnastics and exercise movement techniques. Read More

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http://dx.doi.org/10.1007/s00296-019-04284-xDOI Listing
March 2019
4 Reads

Clinical relevance of monitoring serum adalimumab levels in axial spondyloarthritis.

Rheumatol Int 2019 Mar 21. Epub 2019 Mar 21.

Clinical Medicine Department, Universitas Miguel Hernández, Elche, Alicante, Spain.

Our aim was to assess the relationship between serum adalimumab levels, anti-drug antibodies (ADA) and disease activity in patients with axial spondylarthritis (SpA). We have carried out a single-centre cross-sectional study. adalimumab and ADA levels were analysed with ELISA and correlated with SpA activity using BASDAI and ASDAS scores. Read More

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http://link.springer.com/10.1007/s00296-019-04288-7
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http://dx.doi.org/10.1007/s00296-019-04288-7DOI Listing
March 2019
5 Reads

ESSDAI activity index of the SJÖGRENSER cohort: analysis and comparison with other European cohorts.

Rheumatol Int 2019 Mar 19. Epub 2019 Mar 19.

Rheumatology Department, Hospital Germans Trias i Pujol, Barcelona, Spain.

The objective of the study was to assess the ESSDAI index characteristics in the SJÖGRENSER cohort (Spanish Rheumatology Association's registry of patients with Primary Sjögren Syndrome [PSS]). SJÖGRENSER is a prospective multicentric study on a cohort of Spanish patients with PSS who meet the 2002 American-European consensus from rheumatology units. 298 variables were studied in patients for the inclusion of the study from an anonymous list from each department. Read More

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http://dx.doi.org/10.1007/s00296-019-04285-wDOI Listing
March 2019
1 Read

Rheumatology practice in Japan: challenges and opportunities.

Rheumatol Int 2019 Mar 19. Epub 2019 Mar 19.

Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kita-ku, Sapporo, 060-8638, Japan.

This article aims to and describes the characteristics of rheumatology practice in Japan, focusing on the medical environment for the treatment of rheumatoid arthritis (RA). In Japan, the introduction of biological disease-modifying anti-rheumatic drugs (bDMARDs) has led to a significant paradigm shift in medical care; satisfactory safety outcomes have been demonstrated by periodic analysis, post-market surveillance and the development of guidelines via an industry-academia-government collaboration. Drug discontinuation is also considered an option, as well as medical economic analysis of any increase in the financial burden engendered by use of bDMARDs. Read More

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http://dx.doi.org/10.1007/s00296-019-04281-0DOI Listing
March 2019
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Clinical course of abdominal aortic aneurysms in Behçet disease: a retrospective analysis.

Rheumatol Int 2019 Mar 19. Epub 2019 Mar 19.

Division of Rheumatology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Fatih, 34093, Istanbul, Turkey.

Arterial aneurysms are rare manifestations of Behçet Disease (BD) with high morbidity and mortality. This study aimed to investigate the clinical course of BD patients with abdominal aortic aneurysms (AAA). We retrospectively searched charts of BD patients, followed up between 1988 and 2011, to identify those with AAA with at least 6-month clinical and radiological follow-up data. Read More

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http://dx.doi.org/10.1007/s00296-019-04283-yDOI Listing
March 2019
2 Reads
1.627 Impact Factor

Correction to: Diagnostic utility of a targeted next-generation sequencing gene panel in the clinical suspicion of systemic autoinflammatory diseases: a multi-center study.

Rheumatol Int 2019 Mar 18. Epub 2019 Mar 18.

Department of Molecular Biology-Genetics and Biotechnology, Dr. Orhan Öcalgiray Molecular Biology-Biotechnology and Genetics Research Centre, Graduate School of Science, Engineering and Technology, İstanbul Technical University, Ayazağa Campus, Maslak, 34469, Istanbul, Turkey.

The second affiliation of the corresponding author Eda Tahir Turanlı was incorrectly published as İstanbul Medeniyet University instead of Istanbul Technical University. Read More

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http://dx.doi.org/10.1007/s00296-019-04280-1DOI Listing

Should nasal biopsy inevitably be performed for classifying granulomatosis with polyangiitis in patients with rhinosinusitis? A retrospective chart review study.

Rheumatol Int 2019 Mar 18. Epub 2019 Mar 18.

Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.

Nasal biopsy is the essential method for differentiating and diagnosing granulomatosis with polyangiitis (GPA) in patients with chronic rhinosinusitis. Nevertheless, in the real clinical settings, there are several cases unable for nasal biopsy. Hence, in this study, we investigated initial clinical manifestations and laboratory factors which could be helpful for diagnosing GPA in cases unable for nasal biopsy performance. Read More

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http://dx.doi.org/10.1007/s00296-019-04282-zDOI Listing
March 2019
1 Read

Progression of atherosclerosis versus arterial stiffness with age within and between arteries in systemic lupus erythematosus.

Rheumatol Int 2019 Mar 16. Epub 2019 Mar 16.

Divisions of Cardiology and Rheumatology, Department of Medicine, University of New Mexico School of Medicine, Cardiology 5-ACC, MSC 10-5550, University of New Mexico, Albuquerque, NM, 87131-0001, USA.

The progression of atherosclerosis versus arterial stiffness with age within and between arteries has not been defined. Systemic lupus erythematosus (SLE) is a human model of accelerated arterial disease that may permit this determination. 76 SLE patients (69 women, age 37 ± 12 years) and 26 age-and-sex-matched controls (22 women, age 34 ± 11 years) underwent transesophageal echocardiography and carotid ultrasonography for assessment of atherosclerosis [plaques and intima-media thickening (IMT)] and arterial stiffness [increased pressure-strain elastic modulus (PSEM)] of the descending thoracic aorta and carotid arteries. Read More

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http://dx.doi.org/10.1007/s00296-019-04267-yDOI Listing
March 2019
1 Read

Unmet needs in the treatment of ankylosing spondylitis: a long-term observational study from a single university center.

Rheumatol Int 2019 Apr 15;39(4):663-668. Epub 2019 Mar 15.

Rheumatology Clinic, Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece.

Despite the progress in the treatment of ankylosing spondylitis (AS), a significant number of patients do not achieve low disease activity (LDA). The aim of the study is to estimate the size of unmet needs in the treatment of AS in a long-term observational study. Between January 2003 and December 2017, 220 patients with radiographic SpA were evaluated fulfilling the ASAS criteria. Read More

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http://dx.doi.org/10.1007/s00296-019-04277-wDOI Listing
April 2019
1 Read
1.627 Impact Factor

Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio as predictors of 12-week treatment response and drug persistence of anti-tumor necrosis factor-α agents in patients with rheumatoid arthritis: a retrospective chart review analysis.

Rheumatol Int 2019 Mar 14. Epub 2019 Mar 14.

Division of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Pusan National University Hospital, 179 Gudeok-Ro, Seo-Gu, Busan, 49241, South Korea.

Data are scarce regarding the association of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with treatment response and persistence of anti-TNF-α agents in patients with rheumatoid arthritis (RA). Thus, we investigated whether baseline NLR and PLR could predict 12-week treatment response and long-term persistence of anti-TNF-α agents in RA patients. This is a retrospective chart review analysis of 82 women with RA who started anti-TNF-α agents as the first-line biologic therapy and 328 healthy age-matched women. Read More

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http://dx.doi.org/10.1007/s00296-019-04276-xDOI Listing

Systemic vasculitis involving the breast: a case report and literature review.

Rheumatol Int 2019 Mar 14. Epub 2019 Mar 14.

Department of Rheumatology and Immunology, Peking University Third Hospital, No. 49, North Garden Road, Beijing, 100191, China.

Systemic vasculitis involving the breast is a rare clinical condition and may mimic breast cancer or mastitis clinically or radiographically. Here, we report a case of polyarteritis nodosa (PAN) with breast involvement and perform a literature review of published cases of systemic vasculitis affecting the breast to better understand this disorder. We report a case of PAN affecting the right breast in a young woman. Read More

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http://link.springer.com/10.1007/s00296-019-04279-8
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http://dx.doi.org/10.1007/s00296-019-04279-8DOI Listing
March 2019
4 Reads

Is it required to routinely check fibrinogen level in patients with rheumatic diseases on tocilizumab? Case-based review.

Rheumatol Int 2019 Apr 14;39(4):743-750. Epub 2019 Mar 14.

Division of Rheumatology, Department of Internal Medicine, Eskişehir Osmangazi University, Eskisehir, Turkey.

Tocilizumab (TCZ) may rarely cause hematological side effects including neutropenia and thrombocytopenia. TCZ is essentially expected to lower the fibrinogen levels to stay within the normal range, but TCZ-induced hypofibrinogenemia has been rarely reported in literature. Although it may remain asymptomatic, hypofibrinogenemia has clinical significance owing to the tendency of the condition to result in bleeding. Read More

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http://link.springer.com/10.1007/s00296-019-04268-x
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http://dx.doi.org/10.1007/s00296-019-04268-xDOI Listing
April 2019
3 Reads

Analysis of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio and mean platelet volume to platelet count ratio in children with acute stage of immunoglobulin A vasculitis and assessment of their suitability for predicting the course of the disease.

Rheumatol Int 2019 Mar 13. Epub 2019 Mar 13.

Department of Paediatrics, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, ul. 3-go Maja 13-15, 41-800, Zabrze, Poland.

Immunoglobulin A vasculitis (IgAV) is the most common systemic vasculitis in developmental age. The disease is most often characterized by a self-limiting course and good prognosis, but sometimes serious complications, like gastrointestinal bleeding or glomerulonephritis, may develop. The neutrophil to lymphocyte (NLR) and the platelet to lymphocyte (PLR) ratios are indicators related to clinical outcome in various inflammatory diseases. Read More

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http://dx.doi.org/10.1007/s00296-019-04274-zDOI Listing
March 2019
4 Reads

Color Doppler imaging of ocular hemodynamic changes in patients with rheumatoid arthritis unrelated to disease activity.

Rheumatol Int 2019 Mar 12. Epub 2019 Mar 12.

Department of Ophthalmology, Yildirim Beyazit University Faculty of Medicine, Ankara, Turkey.

We aimed to investigate how orbital blood flow rates in patients with rheumatoid arthritis (RA) are affected by the active and remission phase of the disease. This prospective study included a total of 56 patients with RA (study group) and 24 control individuals (control group). All RA patients were divided into two groups, as active (Group 1) and remission (Group 2) according to the disease activity index (DAS 28) score. Read More

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http://dx.doi.org/10.1007/s00296-019-04275-yDOI Listing
March 2019
5 Reads

Behaviour change interventions targeting physical activity in adults with fibromyalgia: a systematic review.

Rheumatol Int 2019 Mar 12. Epub 2019 Mar 12.

School of Medicine, Discipline of Physiotherapy, Trinity College Dublin, Dublin, Ireland.

Physical activity (PA) and exercise programmes are recommended for the management of fibromyalgia. Despite positive effects on symptoms and function, PA promotion remains a significant clinical challenge. Behaviour change theories and techniques are recommended as part of complex health interventions; their integration into interventions aimed at PA behaviour in people with fibromyalgia is not known. Read More

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http://dx.doi.org/10.1007/s00296-019-04270-3DOI Listing
March 2019
5 Reads

Fatty infiltration in the thigh muscles in knee osteoarthritis: a systematic review and meta-analysis.

Rheumatol Int 2019 Apr 9;39(4):627-635. Epub 2019 Mar 9.

Department of Physical Therapy, Center of Biological and Health Sciences, Federal University of São Carlos, Washington Luiz Road, km 235, SP-310, Mailbox: 676, São Carlos, São Paulo, 13565-905, Brazil.

Knee osteoarthritis is a chronic degenerative joint disease, influenced by inflammatory, mechanical and metabolic processes. Current literature shows that thigh muscles of people with knee osteoarthritis can have increased infiltration of fat, both between and within the muscles (inter- and intramuscular fat). The fatty infiltration in the thigh in this population is correlated to systemic inflammation, poor physical function, and muscle impairment and leads to metabolic impairments and muscle disfunction. Read More

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http://dx.doi.org/10.1007/s00296-019-04271-2DOI Listing

Real-world incidence and prevalence of low back pain using routinely collected data.

Rheumatol Int 2019 Apr 8;39(4):619-626. Epub 2019 Mar 8.

Department of Health Professions, Faculty of Health, Psychology and Social Care, Manchester Metropolitan University, Manchester, M15 6GX, UK.

Low back pain (LBP) is a common health problem among adults of working age population, and its prevalence or incidence increases with increasing in age. The purpose of this review was to examine the real-world prevalence or incidence of LBP. A systematic review of the literature was conducted in accordance to the PRISMA guideline. Read More

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http://dx.doi.org/10.1007/s00296-019-04273-0DOI Listing

Association between disease activity measured by RAPID3 and health-related quality of life in patients with rheumatoid arthritis.

Rheumatol Int 2019 Mar 7. Epub 2019 Mar 7.

University Department for Rheumatology, Physical and Rehabilitation Medicine, University Hospital Centre Sestre Milosrdnice, Vinogradska c. 29, 10000, Zagreb, Croatia.

Routine assessment of patient index data 3 (RAPID3) is a simple, valid and reliable tool designed to measure disease activity in patients with rheumatoid arthritis (RA). RA causes significant disability and diminishes health-related quality of life (HR-QoL). The aim of this study was to investigate how RAPID3 is related to HR-QoL in patients with RA. Read More

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http://dx.doi.org/10.1007/s00296-019-04258-zDOI Listing
March 2019
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1.627 Impact Factor

Accuracy, completeness and accessibility of online information on fibromyalgia.

Rheumatol Int 2019 Apr 6;39(4):735-742. Epub 2019 Mar 6.

Department of Clinical and Experimental Medicine and Neuroscience, Brighton and Sussex Medical School, Falmer, Brighton, BN1 9RY, UK.

Fibromyalgia is a multi-factorial illness primarily characterised by widespread chronic pain and fatigue, with several symptoms and associated conditions. Due to a lack of clinical awareness and an absence of objective diagnostic measures, fibromyalgia patients often engage with online health information. The aim is to investigate the completeness and trustworthiness of the information available online on fibromyalgia. Read More

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http://dx.doi.org/10.1007/s00296-019-04265-0DOI Listing
April 2019
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Challenges in the diagnosis and treatment of disabling pansclerotic morphea of childhood: case-based review.

Rheumatol Int 2019 Mar 5. Epub 2019 Mar 5.

Paediatric Rheumatology Unit, The Royal Children's Hospital, Parkville, VIC, Australia.

Disabling pansclerotic morphea of childhood (DPMC) is a rare subtype of juvenile localized scleroderma (JLS) characterized by pansclerosis mainly affecting children under the age of 14. This aggressive disease has a poor prognosis due to the rapid progression of deep musculoskeletal atrophy resulting in cutaneous ulceration and severe joint contractures. We describe the challenges in treating a previously well 5-year-old male who has refractory symptoms of DPMC. Read More

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http://dx.doi.org/10.1007/s00296-019-04269-wDOI Listing

Use of systemic glucocorticoids in patients with psoriatic arthritis by Argentinian and other Latin-American rheumatologists.

Rheumatol Int 2019 Apr 4;39(4):723-727. Epub 2019 Mar 4.

Rheumatology Service, J. M. Ramos Mejía Hospital, 609, Urquiza Street, 1221, Buenos Aires, Argentina.

To analyse the administration of systemic glucocorticoids (SGC) to patients with Psoriatic arthritis (PsA). Online, anonymous, multiple-choice, closed-ended survey on SGC use in PsA, dose, duration of therapy, and the reason for administration. One hundred and twenty rheumatologists from Argentina (ARG) and 75 from other countries in Latin-America (LAT) completed the survey. Read More

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http://dx.doi.org/10.1007/s00296-019-04266-zDOI Listing
April 2019
2 Reads

Polypharmacy in geriatric rheumatology.

Rheumatol Int 2019 Feb 27. Epub 2019 Feb 27.

Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Cukurova University, Adana, Turkey.

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http://dx.doi.org/10.1007/s00296-019-04264-1DOI Listing
February 2019

ANCA positivity at the time of renal biopsy is associated with chronicity index of lupus nephritis.

Rheumatol Int 2019 Feb 26. Epub 2019 Feb 26.

Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

We investigated the association of antineutrophil cytoplasmic antibody (ANCA) positivity with lupus nephritis (LN) activity, histological features and prognosis in Korean patients with biopsy-proven LN having the results of both myeloperoxidase (MPO-ANCA) and proteinase 3 (PR3)-ANCA. We retrospectively reviewed the medical records of 91 LN patients having the results of ANCA. We divided patients with LN into the two groups according to the ANCA positivity. Read More

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http://dx.doi.org/10.1007/s00296-019-04263-2DOI Listing
February 2019
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Power-Doppler perfusion phenotype in RA patients is dependent on anti-citrullinated peptide antibody status, not on rheumatoid factor.

Rheumatol Int 2019 Feb 26. Epub 2019 Feb 26.

Department of Rheumatology, Medical Clinic II, University Clinic Würzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.

It is not known whether there are any consistent non-serological differences between seropositive and seronegative rheumatoid arthritis, and if any, whether they depend upon rheumatoid factor (RF), anti-citrullinated peptide antibodies (ACPA), or both. In a pilot study, we showed that the two forms could be differentiated using power-Doppler sonography (PDS), and that the difference is ACPA dependent. This extended study explored whether the previous findings could be confirmed. Read More

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http://dx.doi.org/10.1007/s00296-019-04256-1DOI Listing
February 2019
2 Reads

The Greek (Hellenic) rheumatology over the years: from ancient to modern times.

Rheumatol Int 2019 Feb 25. Epub 2019 Feb 25.

SOTIRIA general Hospital, 11527, Athens, Greece.

Rheumatology has its roots in ancient Greece. Hippocrates and other prominent Greek (Hellenes) physicians in ancient times, Hellenistic, Roman, and Byzantine period were acute observers of disease course and of patients and were able to define many disorders. They wrote books on various aspects of medicine and these writings were the basis of medical practice and education in Europe and the Arabic world well into the seventeenth century. Read More

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http://dx.doi.org/10.1007/s00296-019-04261-4DOI Listing
February 2019
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The right place of interleukin-1 inhibitors in the treatment of Behçet's syndrome: a systematic review.

Rheumatol Int 2019 Feb 25. Epub 2019 Feb 25.

Department of Experimental and Clinical Medicine, University of Firenze, Florence, Italy.

Behçet's syndrome (BS) is a chronic (auto)-inflammatory disorder characterized by different clusters of symptoms, including mucocutaneous and ocular involvements. Interleukin-1 inhibitors anakinra (ANA), canakinumab (CAN), and gevokizumab (GEV) represent a promising therapeutic alternative in BS. To date, evidence on the use of ANA, CAN, and GEV is mainly based on small isolated studies or case series, and the real place of anti-IL1 agents in the treatment of BS is still unclear. Read More

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http://dx.doi.org/10.1007/s00296-019-04259-yDOI Listing
February 2019
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Disability due to rheumatic diseases in the city of Junín, Argentina.

Rheumatol Int 2019 Apr 25;39(4):729-733. Epub 2019 Feb 25.

Dirección para las Personas con Discapacidad, Municipalidad de Junín, Junín, Provincia De Buenos Aires, Argentina.

The aim of the study is to analyze the characteristics of patients with rheumatic diseases applying for a Disability Certificate (DC). Every application for DC filed by patients of 16 years of age and older in the Health Secretariat of Junin, between 2012 and 2016, was analyzed regarding age, gender, rheumatic disease as the cause of disability, employment status, and health insurance coverage. Applications were examined as per two elements: inflammatory articular or systemic disease (IASD) versus degenerative diseases, regional or generalized pain syndromes (non-IASD). Read More

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http://dx.doi.org/10.1007/s00296-019-04260-5DOI Listing
April 2019
3 Reads

Think twice before submitting your precious articles for publication!

Rheumatol Int 2019 Feb 23. Epub 2019 Feb 23.

Department of Physical Medicine and Rehabilitation, Cukurova University Faculty of Medicine, Adana, Turkey.

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http://dx.doi.org/10.1007/s00296-019-04262-3DOI Listing
February 2019

Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome: main features and an algorithm for clinical practice.

Authors:
Ezgi Deniz Batu

Rheumatol Int 2019 Feb 23. Epub 2019 Feb 23.

Division of Rheumatology, Department of Pediatrics, Ankara Training and Research Hospital, University of Health Sciences, 06100, Ankara, Turkey.

Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is a recurrent fever syndrome of early childhood with increasing number of adult-onset cases. Although it is a self-limited disease, it may negatively affect the quality of life. The aim of this review is to present a detailed analysis of PFAPA syndrome and an algorithm for diagnosis, therapeutic options, and evaluation of outcome. Read More

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http://link.springer.com/10.1007/s00296-019-04257-0
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http://dx.doi.org/10.1007/s00296-019-04257-0DOI Listing
February 2019
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Liver dysfunction in anti-melanoma differentiation-associated gene 5 antibody-positive patients with dermatomyositis.

Rheumatol Int 2019 Feb 21. Epub 2019 Feb 21.

Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Tochigi, Japan.

The objective was to investigate the clinical and histological features of liver dysfunction in patients with polymyositis (PM) or dermatomyositis (DM).A total of 115 patients (38 with PM and 77 with DM), who were admitted to our hospital between 2001 and 2012, were retrospectively reviewed. Liver dysfunction was defined as an alanine transaminase (ALT) level ≥ 60 U/l and a disproportionate ALT elevation relative to the creatine kinase level. Read More

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http://dx.doi.org/10.1007/s00296-019-04255-2DOI Listing
February 2019
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Diagnostic utility of a targeted next-generation sequencing gene panel in the clinical suspicion of systemic autoinflammatory diseases: a multi-center study.

Rheumatol Int 2019 Feb 19. Epub 2019 Feb 19.

Department of Molecular Biology-Genetics and Biotechnology, Dr. Orhan Öcalgiray Molecular Biology-Biotechnology and Genetics Research Centre, Graduate School of Science, Engineering and Technology, İstanbul Technical University, Ayazağa Campus, Maslak, 34469, Istanbul, Turkey.

Systemic autoinflammatory diseases (sAIDs) are a heterogeneous group of disorders, having monogenic inherited forms with overlapping clinical manifestations. More than half of patients do not carry any pathogenic variant in formerly associated disease genes. Here, we report a cross-sectional study on targeted Next-Generation Sequencing (NGS) screening in patients with suspected sAIDs to determine the diagnostic utility of genetic screening. Read More

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http://dx.doi.org/10.1007/s00296-019-04252-5DOI Listing
February 2019
4 Reads