5,555 results match your criteria Rheumatology International[Journal]


Role of inflammation in the pathogenesis and treatment of fibromyalgia.

Rheumatol Int 2019 Feb 13. Epub 2019 Feb 13.

Department of Physical Medicine and Rehabilitation, Cukurova University Faculty of Medicine, Adana, Turkey.

Fibromyalgia is a multifaceted disease. The clinical picture of fibromyalgia covers numerous comorbidities. Each comorbidity stands as a distinct condition. Read More

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http://dx.doi.org/10.1007/s00296-019-04251-6DOI Listing
February 2019

Hand grip endurance moderating the effect of grip force on functional ability and disease activity in rheumatoid arthritis patients: a cross-sectional study.

Rheumatol Int 2019 Feb 12. Epub 2019 Feb 12.

University Department of Rheumatology, Physical and Rehabilitation Medicine, Clinical Hospital Centre Sestre milosrdnice, Vinogradska 29, HR-10.000, Zagreb, Croatia.

To examine the effect of endurance on the relationship between grip force and measures of functional capacity and disease activity, we performed a cross-sectional study at the University Department of Rheumatology, Physical medicine and Rehabilitation from January 2017 to August 2018. Functional capacity of the hand was measured by ABILHAND-RA questionnaire and disease activity was assessed by the Disease Activity Score (DAS-28-CRP). All participants underwent dynamometric measurements of maximal grip force and hand grip endurance during repeated gripping. Read More

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http://dx.doi.org/10.1007/s00296-019-04250-7DOI Listing
February 2019

Real-world evidence in rheumatic diseases: relevance and lessons learnt.

Rheumatol Int 2019 Mar 6;39(3):403-416. Epub 2019 Feb 6.

Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, 226014, India.

An emerging trend in the medical literature, including the Rheumatology literature, is that of accumulating large, multicentric, multi-national data based on registries of patients seen in real life situations. Such real-world evidence (RWE) may help provide valuable insights into the long-term outcomes of disease in unselected patients seen in daily practice, including patients belonging to vulnerable populations such as extremes of age, during pregnancy and lactation. Evidences gathered from real life practice settings can help understand drug prescription patterns, including adherence to treatment guidelines, cost-effectiveness of therapy, and real-life long-term outcomes, and adverse effects of treatment with particular medications. Read More

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http://dx.doi.org/10.1007/s00296-019-04248-1DOI Listing
March 2019
1 Read
1.627 Impact Factor

Correction to: On-drug and drug-free remission by baseline symptom duration: abatacept with methotrexate in patients with early rheumatoid arthritis.

Rheumatol Int 2019 Feb 5. Epub 2019 Feb 5.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

The article "On-drug and drug-free remission by baseline symptom duration: abatacept with methotrexate in patients with early rheumatoid arthritis", written by Vivian P.Bykerk, was originally published Online First without open access. Read More

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http://dx.doi.org/10.1007/s00296-018-4232-9DOI Listing
February 2019
1 Read
1.627 Impact Factor

Clinical significance of ocular manifestations in granulomatosis with polyangiitis: association with sinonasal involvement and damage.

Rheumatol Int 2019 Mar 31;39(3):489-495. Epub 2019 Jan 31.

Department of Ophthalmology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col. Sección XVI, Tlalpan, CP 14000, Mexico City, CP, Mexico.

Ocular involvement is present in 50-60% of granulomatosis with polyangiitis (GPA) patients and can affect any part of the ocular globe. The present study describes ophthalmologic manifestations, association with systemic symptoms, disease activity and damage in GPA. A cross-sectional study was conducted including patients with GPA who underwent rheumatologic and ophthalmologic evaluation. Read More

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http://dx.doi.org/10.1007/s00296-019-04242-7DOI Listing
March 2019
2 Reads

Characteristics of individual thigh muscles including cross-sectional area and adipose tissue content measured by magnetic resonance imaging in knee osteoarthritis: a cross-sectional study.

Rheumatol Int 2019 Jan 28. Epub 2019 Jan 28.

Department of Orthopedic Surgery, Akita Hospital, 2-6-12 Takara, Chiryu, Aichi, 472-0056, Japan.

This study aimed to identify the parameters related to the area and adipose tissue content of thigh muscles that are associated with radiographic knee osteoarthritis grade. Fifty patients (mean age ± standard deviation, 73.0 ± 4. Read More

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http://dx.doi.org/10.1007/s00296-019-04247-2DOI Listing
January 2019

Time until onset of action when treating psoriatic arthritis: meta-analysis and novel approach of generating confidence intervals.

Rheumatol Int 2019 Jan 25. Epub 2019 Jan 25.

Division of Evidence-Based Medicine (dEBM), Department of Dermatology, Venerology und Allergy, Berlin Institute of Health, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.

Psoriatic arthritis (PsA) is associated with progressive joint destruction and reduced quality of life. The time until a drug treatment starts to show an effect (TOA) is important for preventing joint destruction. The objective was to assess the time until onset of action of drugs when treating PsA. Read More

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http://dx.doi.org/10.1007/s00296-019-04244-5DOI Listing
January 2019
2 Reads

Incidence of infection other than tuberculosis in patients with autoimmune rheumatic diseases treated with bDMARDs: a real-time clinical experience from India.

Rheumatol Int 2019 Mar 25;39(3):497-507. Epub 2019 Jan 25.

ChanRe Rheumatology and Immunology Center and Research, No. 65 (414), 20th Main, West of Chord Road, 1st Block, Rajajinagar, Bangalore-10, India.

Biologic disease-modifying anti-rheumatic drugs (bDMARD) have transformed the treatment paradigm of chronic autoimmune rheumatic diseases (ARDs), but they are often associated with adverse drug reactions. The present study evaluated the frequency, characteristics and type of infections, other than tuberculosis (TB), in ARD patients receiving bDMARDs. The multicentre, cross-sectional, retrospective, observational study was conducted across 12 centers in Karnataka, India, between January to August 2016. Read More

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http://link.springer.com/10.1007/s00296-019-04245-4
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http://dx.doi.org/10.1007/s00296-019-04245-4DOI Listing
March 2019
5 Reads

The association of CAT-262C/T polymorphism with catalase activity and treatment response in juvenile idiopathic arthritis.

Rheumatol Int 2019 Mar 24;39(3):551-559. Epub 2019 Jan 24.

Faculty of Medicine, Department of Biochemistry, University of Niš, Bulevar dr Zorana Djindjića 81, Niš, 18000, Serbia.

Oxidative stress is believed to be of great importance for both the etiology and the persistence of juvenile idiopathic arthritis (JIA). The aim of this study was to investigate the association of -262C/T polymorphism of the catalase (CAT) gene with JIA, as well as to evaluate whether this polymorphism can influence plasma CAT activity and outcome in JIA patients treated with etanercept. A total of 154 subjects (60 JIA patients and 94 healthy volunteers) were screened for CAT-262C/T gene polymorphism using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. Read More

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http://dx.doi.org/10.1007/s00296-019-04246-3DOI Listing
March 2019
4 Reads

Infliximab-associated focal segmental glomerulosclerosis in a patient with ankylosing spondylitis.

Rheumatol Int 2019 Mar 23;39(3):561-567. Epub 2019 Jan 23.

Division of Rheumatology, Department of Internal Medicine, Dokuz Eylul University School of Medicine, Izmir, Turkey.

The introduction of tumor necrosis factor-alpha (TNF-α)-targeting drugs has given new opportunities in the treatment of various inflammatory rheumatic diseases and has been the most important development in the treatment of spondyloarthritis (SpA). However, the increasing use and longer follow-up periods of treatment also pose risks of developing various adverse effects ranging from common ones including infections to uncommon renal complications. This report describes a case of infliximab-induced focal segmental glomerulosclerosis (FSGS) in a 40-year-old female patient with ankylosing spondylitis (AS) who presented with asymptomatic proteinuria and microscopic hematuria. Read More

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http://link.springer.com/10.1007/s00296-019-04241-8
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http://dx.doi.org/10.1007/s00296-019-04241-8DOI Listing
March 2019
4 Reads

Hand and knee osteoarthritis are associated with reduced diameters in retinal vessels: the AGES-Reykjavik study.

Rheumatol Int 2019 Jan 22. Epub 2019 Jan 22.

National Eye Institute, National Institutes of Health (NIH), Bethesda, MD, USA.

To investigate the association between osteoarthritis (OA) and microvascular pathology, we examined the relationship between retinal microvascular caliber and osteoarthritis of the hand and knee in an elderly population. The AGES-Reykjavik is a population-based, multidisciplinary longitudinal cohort study of aging. Retinal vessel caliber, hand osteoarthritis and total knee joint replacements due to OA were examined in 4757 individuals (mean age 76 ± 5 years; 57% female). Read More

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http://link.springer.com/10.1007/s00296-019-04243-6
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http://dx.doi.org/10.1007/s00296-019-04243-6DOI Listing
January 2019
4 Reads

Secular trends in the incidence and prevalence of rheumatoid arthritis within members of an integrated health care delivery system.

Rheumatol Int 2019 Mar 17;39(3):541-549. Epub 2019 Jan 17.

Department of Research and Evaluation, Kaiser Permanente Southern California, 100 S. Los Robles Ave., 2nd Floor, Pasadena, CA, 91101, USA.

The study objective was to estimate secular trends in the overall incidence rate (IR) and prevalence rate (PR) of rheumatoid arthritis (RA); and subgroup-specific IR and PR by race, ethnicity, and sex in a multi-ethnic population of a large integrated health care delivery system. An ecological study was conducted within the adult population of Kaiser Permanente Southern California health plan. From January 1995 up to and including December 2014, annual IR and PR were calculated separately by race, ethnicity, sex and pooled overall. Read More

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http://link.springer.com/10.1007/s00296-018-04235-y
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http://dx.doi.org/10.1007/s00296-018-04235-yDOI Listing
March 2019
13 Reads

Increased serum uric acid levels are associated with digital ulcers in patients with systemic sclerosis.

Rheumatol Int 2019 Feb 17;39(2):255-263. Epub 2019 Jan 17.

Division of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Pusan National University Hospital, 179 Gudeok-Ro, Seo-Gu, Busan, 49241, Republic of Korea.

Endothelial injury/dysfunction is thought to be one of the earliest events in the development of vascular diseases in systemic sclerosis (SSc). Although hyperuricemia is also known to induce endothelial dysfunction and vascular inflammation, the effect of uric acid on the microvascular involvement in SSc has not been well established. We investigated whether increased serum uric acid (SUA) levels are associated with digital ulcers (DUs) in SSc. Read More

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http://dx.doi.org/10.1007/s00296-019-04240-9DOI Listing
February 2019
2 Reads

Level of adherence to prescribed exercise in spondyloarthritis and factors affecting this adherence: a systematic review.

Rheumatol Int 2019 Feb 16;39(2):187-201. Epub 2019 Jan 16.

School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, Scotland, UK.

Adherence is a primary determinant of the effectiveness of any intervention. Exercise is considered essential in the management of spondyloarthritis (SpA); however, the overall adherence to exercise programmes and factors affecting adherence are unknown. The aim of this systematic review was to examine measures of, and factors influencing adherence to, prescribed exercise programmes in people with SpA. Read More

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http://dx.doi.org/10.1007/s00296-018-4225-8DOI Listing
February 2019
2 Reads

Determination of magnetic resonance imaging criteria for diagnosis of adhesive capsulitis.

Rheumatol Int 2019 Mar 7;39(3):453-460. Epub 2019 Jan 7.

Pain Research Center, Department of Orthopedic Surgery, Dongsan Medical Center, School of Medicine, Keimyung University, 56 Dalseong-ro, Jung-gu, Daegu, 41931, South Korea.

The objective of this study was to identify optimal magnetic resonance imaging (MRI) parameters and their cutoff values for diagnosing adhesive capsulitis (AC). One hundred shoulder MRI images with stage 2 AC (AC group) and 100 MRI images without AC (control group) were randomly reviewed by two experienced shoulder specialists. They were asked whether MRI findings were compatible with AC and measurement of MRI parameters. Read More

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http://dx.doi.org/10.1007/s00296-018-04238-9DOI Listing
March 2019
2 Reads

Idiopathic hip chondrolysis: a case report of a Caucasian HLA-B27 positive adolescent with a history of long walking.

Rheumatol Int 2019 Jan 5. Epub 2019 Jan 5.

Department of Οrthopedics, University Hospital of Ioannina, Stavros Niarchos Avenue 1, Karaoli kai Dimitriou 5, Ioannina, 45332, Greece.

Idiopathic hip chondrolysis is a rare disorder, the pathophysiology of which has not been fully elucidated. Several theories have been proposed regarding the cause of the disease with some of them involving autoimmune-mediated cartilage destruction. There are several similar features between idiopathic hip chondrolysis and rheumatologic diseases such as juvenile idiopathic arthritis, so whether these two disorders are different or not is still debatable. Read More

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http://dx.doi.org/10.1007/s00296-018-04239-8DOI Listing
January 2019
1 Read
1.627 Impact Factor

Tuberculosis and Takayasu arteritis: case-based review.

Rheumatol Int 2019 Feb 3;39(2):345-351. Epub 2019 Jan 3.

Department of Tropical Medicine and Infectious Diseases, Rostock University Medical Center, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany.

This report presents a case of co-occurrence of Takayasu arteritis (TA) and multiorgan tuberculosis (TB) in a 20-year-old female and provides a review of 18 previously reported cases of co-occurring TA and TB. All patients were between 9 and 24 years of age. Most reports describe a concomitant diagnosis of active TB and TA. Read More

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http://dx.doi.org/10.1007/s00296-018-4231-xDOI Listing
February 2019
2 Reads

Pediatric rheumatology in Turkey.

Rheumatol Int 2019 Mar 3;39(3):431-440. Epub 2019 Jan 3.

Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Pediatric Rheumatology is an emerging specialty in Turkey with increasing number of available centers and specialists all over the country. In this paper, we sought to provide an overview on pediatric rheumatology service in our country, as well as to assess the principle published literature from Turkey in this field. A systematic literature search has been performed to achieve the significance and the impact of this manuscript. Read More

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http://dx.doi.org/10.1007/s00296-018-04236-xDOI Listing
March 2019
3 Reads

Efficacy and safety of long-term treatment with intravenous colchicine for familial Mediterranean fever (FMF) refractory to oral colchicine.

Rheumatol Int 2019 Mar 2;39(3):517-523. Epub 2019 Jan 2.

Department of Internal Medicine F, The Chaim Sheba Medical Center, 52621, Tel-Hashomer, Israel.

Colchicine is the mainstay of treatment for familial Mediterranean fever (FMF). Intravenous (IV) colchicine, administered over several months, has been shown to be effective for FMF patients unresponsive to oral colchicine. The objective of this study was to evaluate the efficacy and safety of long-term IV colchicine treatment in oral colchicine-resistant FMF. Read More

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http://dx.doi.org/10.1007/s00296-018-04237-wDOI Listing
March 2019
2 Reads
1.627 Impact Factor

Supervised walking improves cardiorespiratory fitness, exercise tolerance, and fatigue in women with primary Sjögren's syndrome: a randomized-controlled trial.

Rheumatol Int 2019 Feb 2;39(2):227-238. Epub 2019 Jan 2.

Department of Rheumatology, Universidade Federal de São Paulo-Escola Paulista de Medicina, Rua Botucatu, 740, São Paulo, SP, 04023-900, Brazil.

Objective: The aim of this study was to evaluate the safety and effectiveness of a supervised walking program in women with primary Sjögren's syndrome (pSS).

Methods: Forty-five sedentary women fulfilling the American European Consensus Criteria for pSS were randomized to a training group (TG, n = 23) or control group (CG, n = 22). Patients in the TG were submitted to supervise walking three times a week for 16 weeks. Read More

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http://dx.doi.org/10.1007/s00296-018-4213-zDOI Listing
February 2019
3 Reads

Reliability of real-world data.

Rheumatol Int 2019 Mar 2;39(3):583-584. Epub 2019 Jan 2.

Department of Physical Medicine and Rehabilitation, Cukurova University Faculty of Medicine, Adana, Turkey.

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http://dx.doi.org/10.1007/s00296-018-4230-yDOI Listing
March 2019
1 Read

Early outcomes in kidney transplant recipients with systemic lupus erythematosus.

Rheumatol Int 2019 Mar 2;39(3):479-487. Epub 2019 Jan 2.

Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col. Sección XVI, Tlalpan, CP 14000, Mexico City, Mexico.

Kidney transplant (KT) is the best treatment for patients who progress to end-stage renal disease. Short-term outcomes in patients with systemic lupus erythematosus (SLE) following KT are not well known. To describe the postoperative outcomes and complications in SLE patients undergoing KT, we conducted a case-control study from 2010 to 2015 including SLE recipients compared to non-SLE controls matched by age and sex. Read More

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http://dx.doi.org/10.1007/s00296-018-4234-7DOI Listing
March 2019
2 Reads

Dietary protein intake and upper leg muscle strength in subjects with knee osteoarthritis: data from the osteoarthritis initiative.

Rheumatol Int 2019 Feb 2;39(2):277-284. Epub 2019 Jan 2.

Department of Rehabilitation Medicine, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

The aims of this study were (1) to describe dietary protein intake, and (2) to evaluate the association between dietary protein intake and upper leg muscle strength in subjects with knee osteoarthritis (OA). Baseline data from the OA was used, in a cross-sectional study. All subjects were diagnosed with symptomatic and radiographic knee OA. Read More

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http://dx.doi.org/10.1007/s00296-018-4223-xDOI Listing
February 2019
3 Reads

Inhibition of periarticular bone loss is associated with clinical remission and ACR70-Response in rheumatoid arthritis.

Rheumatol Int 2018 Dec 19. Epub 2018 Dec 19.

Institute of Diagnostic and Interventional Radiology, SRH Wald-Klinikum Gera, Straße des Friedens 122, 07548, Gera, Germany.

The aim of this study, based on a post hoc analysis of the data set used in the RAPID 1 trial, focuses on the associations between metacarpal bone mineral density, as estimated by digital X-ray radiogrammetry (DXR), and clinical remission as well as ACR70-Response in rheumatoid arthritis (RA) patients treated with certolizumab pegol (CZP). The trial evaluates a total of 345 RA patients treated with methotrexate versus CZP 200 mg versus CZP 400 mg. All patients underwent X-rays of the hand at baseline and week 52 as well as computerized calculations of bone mineral density (BMD) by DXR. Read More

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http://dx.doi.org/10.1007/s00296-018-4226-7DOI Listing
December 2018
2 Reads

Clinical characteristics of avascular necrosis in patients with Behçet disease: a case series and literature review.

Rheumatol Int 2019 Jan 17;39(1):153-159. Epub 2018 Dec 17.

Division of Rheumatology, Department of Internal Medicine, Gazi University Faculty of Medicine, 06100, Ankara, Turkey.

Avascular necrosis (AVN), also known as osteonecrosis, is characterized by death of the osteocytes due to inadequate blood supply caused by various mechanisms. The hip is the most common affected joint followed by knee. Incidence of AVN in rheumatic diseases is variable and high corticosteroid (CS) therapy is a known major risk factor for development of AVN. Read More

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http://link.springer.com/10.1007/s00296-018-4224-9
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http://dx.doi.org/10.1007/s00296-018-4224-9DOI Listing
January 2019
5 Reads

Systemic sclerosis induced by the use of cocaine: is there an association?

Rheumatol Int 2019 Feb 15;39(2):387-393. Epub 2018 Dec 15.

Division of Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Av. Dr. Arnaldo, 455 -3° andar, sala 3131, Cerqueira César, São Paulo, CEP 01246-903, Brazil.

The association between cocaine abuse and systemic sclerosis (SSc) is rarely described. Two new cases of this association are presented: two young adults, after using inhaled cocaine for a few years, were diagnosed with SSc. While a 24 year-old white female patient presented with diffuse SSc with multiple digital ulcers and scleroderma renal crisis (SRC), a 27 year-old male patient presented limited SSc with skin ulcers and digital gangrene, rapidly evolving to death due to massive intestinal hemorrhage. Read More

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http://dx.doi.org/10.1007/s00296-018-4227-6DOI Listing
February 2019
2 Reads

Thrombotic microangiopathy in a patient with eosinophilic granulomatosis with polyangiitis: case-based review.

Rheumatol Int 2019 Feb 15;39(2):359-365. Epub 2018 Dec 15.

Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Virgen de las Nieves University Hospital, Granada, Spain.

The correct diagnosis, classification and therapeutic management of thrombotic microangiopathies (TMA) continue to be a challenge for the clinician. We report a rare case of eosinophilic granulomatosis with polyangiitis (EGPA) as a trigger for complement-mediated TMA in a 57-year-old man who was successfully treated with corticoids, cyclophosphamide and therapeutic plasma exchange. Additionally, we review few other cases reported in the literature and the pathophysiological pathway of association between TMA and EGPA. Read More

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http://link.springer.com/10.1007/s00296-018-4228-5
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http://dx.doi.org/10.1007/s00296-018-4228-5DOI Listing
February 2019
9 Reads

Juvenile dermatomyositis with IgA nephropathy: case-based review.

Rheumatol Int 2019 Mar 14;39(3):577-581. Epub 2018 Dec 14.

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

Juvenile dermatomyositis (JDM) is the most common childhood idiopathic inflammatory myopathy (IIM). It is characterized by the classic skin rash in the form of Gottron papules and heliotrope rash, and symmetric proximal muscle weakness. Renal involvement in JDM is rare which includes acute kidney injury and glomerulonephritis. Read More

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http://dx.doi.org/10.1007/s00296-018-4229-4DOI Listing
March 2019
10 Reads

MicroRNA-124 inhibits TNF-α- and IL-6-induced osteoclastogenesis.

Rheumatol Int 2018 Dec 14. Epub 2018 Dec 14.

Division of Laboratory Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

Receptor activator for nuclear factor κB ligand (RANKL)-independent osteoclastogenic pathway was reported recently. MicroRNA (miR)-124 has been known to suppress RANKL-dependent osteoclastogenesis by inhibiting NFATc1 expression. However, whether miR-124 regulates a RANKL-independent pathway has not been elucidated. Read More

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http://dx.doi.org/10.1007/s00296-018-4218-7DOI Listing
December 2018
1 Read

Granuloma annulare development in a patient with rheumatoid arthritis treated with tocilizumab: case-based review.

Rheumatol Int 2019 Feb 7;39(2):353-357. Epub 2018 Dec 7.

Department of Internal Medicine, Rheumatology Clinic, Medical School, University of Ioannina, 45110, Ioannina, Greece.

Granuloma annulare (GA) is the most common non-infectious disease. Despite the fact that it is a benign disease, it can be associated with a variety of disorders and certain drugs including biological disease-modifying anti-rheumatic drugs (bDMARDs). A 50-year-old man with a history of rheumatoid arthritis refractory to methotrexate, hydroxychloroquine and infliximab was treated with tocilizumab (TCZ), an interleukin-6 receptor antagonist, 162 mg subcutaneously every week. Read More

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http://dx.doi.org/10.1007/s00296-018-4212-0DOI Listing
February 2019
5 Reads
1.627 Impact Factor

Validity and reliability of the ten-item Connor-Davidson Resilience Scale (CD-RISC10) instrument in patients with axial spondyloarthritis (axSpA) in Singapore.

Rheumatol Int 2019 Jan 6;39(1):105-110. Epub 2018 Dec 6.

Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore.

We aimed to assess the validity and reliability of the ten-item Connor-Davidson Resilience Scale (CD-RISC10) in patients with axial spondyloarthritis (axSpA) in Singapore. We used cross-sectional data from 108 patients with axSpA recruited from a dedicated axSpA clinic in a Singapore tertiary referral hospital from 2017 to 2018. Analyses were guided by the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) framework. Read More

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http://dx.doi.org/10.1007/s00296-018-4217-8DOI Listing
January 2019
1 Read
1.627 Impact Factor

Reliability of OMERACT ultrasound elementary lesions in gout: results from a multicenter exercise.

Rheumatol Int 2018 Dec 11. Epub 2018 Dec 11.

Rheumatology Unit, Instituto de Rehabilitación Psicofísica, Echeverria 955, Buenos Aires, C1428DQG, Argentina.

The aim of this study was to evaluate the reliability of the outcome measures in rheumatology (OMERACT) definitions for ultrasound (US) elementary lesions in gout through an image reading exercise. Images from patients with gout (static images and videos) were collected. As an initial step, we carried out a image reading exercise within the experts of the Pan-American League of Associations for Rheumatology (PANLAR) US Study Group (n = 16). Read More

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http://dx.doi.org/10.1007/s00296-018-4220-0DOI Listing
December 2018
2 Reads

Immunohistochemical and ultrastructural analysis of sporadic inclusion body myositis: a case series.

Rheumatol Int 2018 Dec 8. Epub 2018 Dec 8.

Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, Chałubińskiego Street 6a, 50-368, Wrocław, Poland.

Sporadic inclusion body myositis (s-IBM) is a progressive, skeletal muscle disease with poor prognosis. However, establishing the final diagnosis is difficult because of the lack of clear biomarkers in the blood serum and very slow development of clinical symptoms. Moreover, most other organs function normally without any disturbance. Read More

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http://dx.doi.org/10.1007/s00296-018-4221-zDOI Listing
December 2018
1 Read

To what extend is nail ultrasound discriminative between psoriasis, psoriatic arthritis and healthy subjects?

Rheumatol Int 2018 Dec 10. Epub 2018 Dec 10.

Department of Social Psychology and Methodology, Facultad de Psicología, Universidad Autónoma de Madrid, Madrid, Spain.

To assess the discriminative utility of nail features detected by B-mode (BM) and color Doppler (CD) ultrasound (US) between patients with psoriasis (PsO) and psoriatic arthritis (PsA) and healthy controls. Sixty patients with PsA, 21 patients with PsO, and 20 healthy controls were prospectively included. All patients underwent a dermatologic assessment and PsA patients also a rheumatologic assessment. Read More

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http://dx.doi.org/10.1007/s00296-018-4222-yDOI Listing
December 2018
4 Reads

Safety of statin drugs in patients with dyslipidemia and stable systemic autoimmune myopathies.

Rheumatol Int 2019 Feb 5;39(2):311-316. Epub 2018 Dec 5.

Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.

Recent studies have shown a high prevalence of dyslipidemia in patients with systemic autoimmune myopathies (SAM). However, little is known about the safety of the use of statins in these patients, and this gap in research motivated the accomplishment of the present study. In a retrospective cohort study conducted from 2004 to 2018, 250 patients with SAM were evaluated, and 24 patients had stable forms of SAM (16 dermatomyositis, 1 polymyositis and 7 antisynthetase syndrome) but had dyslipidemia and had received statins. Read More

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http://dx.doi.org/10.1007/s00296-018-4215-xDOI Listing
February 2019
3 Reads

Advances in rheumatology practice in Brazil.

Rheumatol Int 2018 Dec 1. Epub 2018 Dec 1.

Laboratório de Investigação em Osteoartropatias, Department of Internal Medicine, Liga de Reumatologia e Doenças Autoimunes, Instituto de Biomedicina, Faculdade de Medicina, Federal University of Ceará, Rua Cel. Nunes de Melo, 1315, 1°. Andar, Rodolfo Teófilo, Fortaleza, CE, 60430-270, Brazil.

Despite resilient inequities, Brazil has seen progressive improvement in health care in the last 25 years. Infectious diseases rendered place to chronic non-communicable diseases as a major cause of death. Existence of traditional schools of medicine and training services in rheumatology helped form a reasonable number of specialists, though irregular distribution due to the economic issues favoring their clustering in major cities. Read More

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http://dx.doi.org/10.1007/s00296-018-4211-1DOI Listing
December 2018
3 Reads

Validity and interpretability of the QuickDASH in the assessment of hand disability in rheumatoid arthritis.

Rheumatol Int 2018 Dec 3. Epub 2018 Dec 3.

Rheumatological Clinic, Ospedale "Carlo Urbani", Università Politecnica delle Marche, Via Aldo Moro, 25, Jesi, 60035, Ancona, Italy.

Objective of this study is to evaluate the construct validity and the interpretability of the shortened Disability of Arm, Shoulder and Hand Questionnaire (QuickDASH) in the assessment of rheumatoid arthritis (RA) hand disability. Consecutive RA patients were assessed through the QuickDASH and other function and disease activity indices, respectively, the Health Assessment Questionnaire-Disability Index (HAQ-DI) and the Recent-Onset Arthritis Disability questionnaire (ROAD). For each patient were evaluated the tender and swollen 28-joints counts. Read More

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http://dx.doi.org/10.1007/s00296-018-4216-9DOI Listing
December 2018
2 Reads

Factors related to alexithymia in patients with systemic sclerosis: a tight relationship with facial image dissatisfaction.

Rheumatol Int 2019 Mar 29;39(3):461-467. Epub 2018 Nov 29.

Unit of Allergology, Immunology and Rheumatology, Campus Bio-Medico University of Rome, Via Alvaro del Portillo 200, 00128, Rome, Italy.

To assess clinical and psychosocial factors related to alexithymia in systemic sclerosis (SSc). We enrolled 40 consecutive SSc patients in a cross-sectional study evaluating alexithymia with Toronto Alexithymia scale (TAS-20). We measured Beck Depression inventory (BDI), Hamilton Anxiety rating scale (HAM-H), 36-Items Short-Form Healthy Survey (SF-36), Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue, Visual Analog Scale (VAS) pain, Pittsburgh Sleep Quality Index (PSQI), Satisfaction with Appearance Scale (SWAP), and Mouth Handicap in Systemic Sclerosis (MHISS). Read More

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http://link.springer.com/10.1007/s00296-018-4214-y
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http://dx.doi.org/10.1007/s00296-018-4214-yDOI Listing
March 2019
8 Reads

Persistence with biological drugs in patients treated in rheumatology practices in Germany.

Rheumatol Int 2019 Mar 24;39(3):525-531. Epub 2018 Nov 24.

Epidemiology, IQVIA, Commercial GmbH & Co OHG, Unterschweinstiege 2-14, 60549, Frankfurt am Main, Germany.

The goal of this study was to investigate the persistence with biological drugs in patients treated in rheumatology practices in Germany. This study included patients diagnosed with rheumatoid arthritis (RA), psoriatic arthritis (PA), or ankylosing spondylitis (AS) who received a first prescription of biological drugs between 2008 and 2016 (index date) in 21 rheumatology practices in Germany (n = 4925; Disease Analyzer database). The main outcome measure was the rate of persistence within 5 years of the index date. Read More

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http://dx.doi.org/10.1007/s00296-018-4194-yDOI Listing
March 2019
2 Reads

Tocilizumab treatment in refractory polyarteritis nodosa: a case report and review of the literature.

Rheumatol Int 2019 Feb 21;39(2):337-344. Epub 2018 Nov 21.

Asklepios Klinik Altona, Rheumatologie, Klinische Immunologie, Nephrologie, Paul-Ehrlich-Straße 1, 22763, Hamburg, Germany.

Polyarteritis nodosa (PAN) is a rare systemic vasculitis affecting multiple organs. Current standard treatment includes the use of glucocorticoids and cyclophosphamide. Unfortunately, some patients do not respond to this treatment and other therapeutic options are needed. Read More

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http://dx.doi.org/10.1007/s00296-018-4210-2DOI Listing
February 2019
14 Reads

Genetic variations in the IL-12B gene in association with IL-23 and IL-12p40 serum levels in ankylosing spondylitis.

Rheumatol Int 2019 Jan 15;39(1):111-119. Epub 2018 Nov 15.

Department of Molecular Biology, Immunology and Medical Genetics, Medical Faculty, Trakia University, 11, Armeiska St, 6003, Stara Zagora, Bulgaria.

In the present study, we evaluated the implication of IL12Bpro (rs17860508) and IL12B 3' UTR A/C single nucleotide polymorphisms (SNPs) (rs3212227) for the ankylosing spondylitis (AS) development and the impact of IL12B genetic variations on IL-23 and IL-12p40 production and musculoskeletal disease characteristics. 80 patients with AS and 242 healthy controls were studied. Genotyping for the rs3212227 was performed by restriction fragment length polymorphisms-polymerase chain reaction (PCR) and for the rs17860508 by allele-specific PCR. Read More

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http://dx.doi.org/10.1007/s00296-018-4204-0DOI Listing
January 2019
6 Reads

Strengthening the quadriceps femoris muscle versus other knee training programs for the treatment of knee osteoarthritis.

Rheumatol Int 2019 Feb 15;39(2):203-218. Epub 2018 Nov 15.

Division of Physiotherapy and Rehabilitation, Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Istanbul University-Cerrahpasa, Demirkapı Cad. Karabal, Sk., Bakirkoy, 34740, Istanbul, Turkey.

People with knee osteoarthritis have atrophy of the muscles surrounding the knee joint. Therefore, exercise programs primarily have been focused on the strengthening of quadriceps femoris muscle (QFM). Primary aim of this systematic review was to determine which exercise increases strength of the QFM and describe the details of the training programs. Read More

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http://link.springer.com/10.1007/s00296-018-4199-6
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http://dx.doi.org/10.1007/s00296-018-4199-6DOI Listing
February 2019
24 Reads

The effects of 8-week water-running program on exercise capacity in children with juvenile idiopathic arthritis: a controlled trial.

Rheumatol Int 2019 Jan 14;39(1):59-65. Epub 2018 Nov 14.

Division of Pediatric Rheumatology, Department of Pediatrics, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.

Exercise capacity has been reported to be lower in children with Juvenile Idiopathic Arthritis (JIA). Therefore, the aim was to investigate the effects of an 8-week water-based exercise program on exercise capacity in children with JIA. Forty-two children with JIA were divided into two groups as: exercise group [n = 21, water-running, moderate-intensity exercise (60-70%), two times/week], and control group (n = 21, no additional treatment other than the prescribed medication). Read More

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http://dx.doi.org/10.1007/s00296-018-4209-8DOI Listing
January 2019
9 Reads

Diagnostic/classification criteria in pediatric Behçet's disease.

Authors:
Ezgi Deniz Batu

Rheumatol Int 2019 Jan 14;39(1):37-46. Epub 2018 Nov 14.

Division of Rheumatology, Department of Pediatrics, Ankara Training and Research Hospital, University of Health Sciences, 06100, Ankara, Turkey.

Behçet's disease (BD) is a variable vessel vasculitis characterized by recurrent oral and genital aphthosis accompanied by skin, ocular, gastrointestinal, neurologic, and articular involvement. BD is not common in childhood and the disease characteristics considerably differ between adults and children. 18 diagnostic/classification criteria have been published for BD to date. Read More

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http://dx.doi.org/10.1007/s00296-018-4208-9DOI Listing
January 2019
1 Read

Treatment patterns, unmet need, and impact on patient-reported outcomes of psoriatic arthritis in the United States and Europe.

Rheumatol Int 2019 Jan 13;39(1):121-130. Epub 2018 Nov 13.

Pfizer Inc, New York, NY, USA.

Psoriatic arthritis (PsA) is a chronic, inflammatory disease. The effects of PsA real-world treatment patterns on patient-reported outcomes in the US and 5 European countries (EU5; France, Germany, Italy, Spain, UK) were evaluated. Respondents from the 2016 National Health and Wellness Survey received advanced therapies (e. Read More

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http://link.springer.com/10.1007/s00296-018-4195-x
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http://dx.doi.org/10.1007/s00296-018-4195-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329738PMC
January 2019
10 Reads

Similarity of autoimmune diseases based on the profile of immune complex antigens.

Rheumatol Int 2019 Feb 13;39(2):323-325. Epub 2018 Nov 13.

Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto-machi, Nagasaki, 852-8588, Japan.

Since immune complexes (IC) are a direct product of immune response through the binding between antigen and antibody, the profile of antigen-associated ICs may depend on each autoimmune disease. In this report, we examined the similarity of four neurological autoimmune diseases, Alzheimer's disease and healthy donors, and seven connective tissue diseases based on the profiling of IC-associated antigens which were previously or recently identified by immune complexome analysis of cerebrospinal fluid (CSF) or serum samples. The similarity between each pair of two diseases was assessed by correlation coefficients as distance matrix with the use of detection frequency (i. Read More

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http://link.springer.com/10.1007/s00296-018-4206-y
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http://dx.doi.org/10.1007/s00296-018-4206-yDOI Listing
February 2019
13 Reads

Residual symptoms and disease burden among patients with psoriatic arthritis: is a new disease activity index required?

Rheumatol Int 2019 Jan 13;39(1):73-81. Epub 2018 Nov 13.

Division of Rheumatology and Immunology, Department of Physical Medicine and Rehabilitation, Sakarya University Faculty of Medicine, Sakarya, Turkey.

The aim of this study was to investigate residual symptoms or disease burden among patients with psoriatic arthritis (PsA) in remission or low disease activity (LDA) according to different outcome measures. A total of 126 patients with PsA were included and the following variables were assessed: Tender joint count (TJC), swollen joint count (SJC), patient's global assessment, physician's global assessment, pain, extra-articular manifestations, Psoriasis Area and Severity Index, Health Assessment Questionnaire, fatigue, Short Form-36, psoriatic quality of life, Hospital Anxiety and Depression Scale and C-reactive protein (CRP). Disease activity was measured using three different outcome measures including minimal disease activity (MDA), disease activity score for 28 joints (DAS28-CRP) and disease activity in psoriatic arthritis (DAPSA). Read More

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http://link.springer.com/10.1007/s00296-018-4201-3
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http://dx.doi.org/10.1007/s00296-018-4201-3DOI Listing
January 2019
8 Reads

Persistent eosinophilia in rheumatoid arthritis: a prospective observational study.

Rheumatol Int 2019 Feb 13;39(2):245-253. Epub 2018 Nov 13.

Department of Clinical Immunology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India.

Eosinophilia is an uncommon manifestation in Rheumatoid arthritis (RA), and there is a paucity of data regarding the relationship of eosinophilia with disease-related factors. We prospectively evaluated the clinical and disease-specific characteristics of RA patients with eosinophilia. Consecutive patients with RA with an absolute eosinophil count ≥ 500/mm without an apparent cause for eosinophilia, were investigated for parasitic infestation. Read More

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http://link.springer.com/10.1007/s00296-018-4191-1
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http://dx.doi.org/10.1007/s00296-018-4191-1DOI Listing
February 2019
11 Reads
1.630 Impact Factor

Efficacy and safety of biological therapy compared to synthetic immunomodulatory drugs or placebo in the treatment of Behçet's disease associated uveitis: a systematic review.

Rheumatol Int 2019 Jan 12;39(1):47-58. Epub 2018 Nov 12.

University Hospital Marques of Valdecilla, Santander, Spain.

The aim of this study is to compare the efficacy and safety of biological therapy with cyclosporin A (CsA), azathioprine (AZA), or placebo in uveitis flares and other ocular outcomes in patients with Behçet disease. A comprehensive and sensitive search in MEDLINE, EMBASE, and the Cochrane Library was performed. We selected articles including: (1) adult patients with Behçet's and uveitis; (2) on biological therapies; (3) placebo or active control with CsA or AZA; (4) analyzing efficacy (number of uveitis flares, macular edema, etc. Read More

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http://dx.doi.org/10.1007/s00296-018-4193-zDOI Listing
January 2019
6 Reads