7,623 results match your criteria Rheumatoid Arthritis Hands


The effects of Reiki and hand massage on pain and fatigue in patients with rheumatoid arthritis.

Explore (NY) 2022 Jun 11. Epub 2022 Jun 11.

Aksaray University, Faculty of Health Sciences, Department of Surgical Nursing, Aksaray, Turkey. Electronic address:

Objective: The present study was conducted in order to determine the effects of Reiki and hand massage on the pain and fatigue of patients with rheumatoid arthritis.

Methods: This study having a randomized controlled experimental design was carried out involving 105 individuals (35 in Reiki, 37 in hand massage, and 33 in control). Study data were collected between July 2020 and December 2021 by using a personal information form, Visual Analog Scale, and Piper Fatigue Scale. Read More

View Article and Full-Text PDF

Evidence for the presence of synovial sheaths surrounding the extensor tendons at the metacarpophalangeal joints: a microscopy study.

Arthritis Res Ther 2022 Jun 24;24(1):154. Epub 2022 Jun 24.

Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands.

MRI-detected inflammation around the extensor tendons of metacarpophalangeal (MCP-) joints is prevalent in RA and poses a markedly increased risk of RA development when present in arthralgia patients. Such inflammation is called 'peritendinitis' since anatomy literature reports no presence of a tenosynovial sheath at these tendons. However, the presence or absence of tenosynovium at these extensor tendons has never been studied. Read More

View Article and Full-Text PDF

How long does it to achieve sagittal realignment of the displaced epiphysis in Salter-Harris type II distal radial fracture when treated by manual reduction?

J Plast Surg Hand Surg 2022 Jun 24:1-8. Epub 2022 Jun 24.

Department of Orthopaedic Surgery, Regional Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, South Korea.

This study aimed to investigate how long it takes for the dorsally displaced distal radial epiphysis to achieve realignment. We retrospectively reviewed 56 patients with dorsally displaced Salter-Harris type II distal radial epiphyseal fractures who were aged ≤15 years at the time of injury. All fractures were treated with closed reduction and immobilised using a sugar tong splint for 6 weeks. Read More

View Article and Full-Text PDF

Deep Learning-Based Computer-Aided Diagnosis of Rheumatoid Arthritis with Hand X-ray Images Conforming to Modified Total Sharp/van der Heijde Score.

Biomedicines 2022 Jun 8;10(6). Epub 2022 Jun 8.

Department of Information Management, National Taipei University of Nursing and Health Sciences, Taipei City 112, Taiwan.

Introduction: Rheumatoid arthritis (RA) is a systemic autoimmune disease; early diagnosis and treatment are crucial for its management. Currently, the modified total Sharp score (mTSS) is widely used as a scoring system for RA. The standard screening process for assessing mTSS is tedious and time-consuming. Read More

View Article and Full-Text PDF

Spontaneous Rupture of the Extensor Pollicis Longus Tendon in a Lacrosse Player.

Phys Sportsmed 2022 Jun 23. Epub 2022 Jun 23.

Louisiana State University Health Shreveport, Shreveport, LA.

Spontaneous rupture of the extensor pollicis longus (EPL) tendon at the wrist has been reported with predisposing factors to include distal radius fractures, rheumatoid arthritis, systemic or local steroids and repetitive abnormal motion of the wrist joint. We present a case of an 18-year-old college lacrosse player without history of known predisposing factors who presented with an acute inability to extend the interphalangeal (IP) joint of his right thumb. Preoperative musculoskeletal ultrasound demonstrated rupture of the EPL tendon proximal to the carpometacarpal (CMC) joint of the thumb. Read More

View Article and Full-Text PDF

Rheumatoid Arthritis Symptoms Diagnosed by Rheumatic Immune-related Adverse Events Caused by Nivolumab in a Patient with Esophageal Cancer: A Case Report.

Intern Med 2022 Jun 21. Epub 2022 Jun 21.

Division of Gastroenterology and Nephrology, Faculty of Medicine, Tottori University, Japan.

This report described the case of a 70-year-old man who developed polyarthralgia after nivolumab treatment for recurrent esophageal cancer. Arthritis developed after initiating nivolumab therapy, and the patient tested positive for rheumatoid factor and anti-citrullinated peptide antibodies. The hand and elbow joints were already deformed, suggesting that he had had rheumatoid arthritis for several years and that the symptoms had only become apparent after nivolumab administration. Read More

View Article and Full-Text PDF

CLP1 is a Prognosis-Related Biomarker and Correlates With Immune Infiltrates in Rheumatoid Arthritis.

Front Pharmacol 2022 1;13:827215. Epub 2022 Jun 1.

Department of Orthopaedics, The First Affiliated Hospital, Jinan University, Guangzhou, China.

Rheumatoid arthritis (RA) is a chronic, heterogeneous autoimmune disease with a high disability rate that seriously affects society and individuals. However, there is a lack of effective and reliable diagnostic markers and therapeutic targets. In this study, we identified diagnostic markers of RA based on RNA modification and explored its role as well as degree of immune cell infiltration. Read More

View Article and Full-Text PDF

Use of primary health care and radiological imaging preceding a diagnosis of rheumatoid arthritis: a nationwide cohort study in Denmark.

Rheumatology (Oxford) 2022 Jun 17. Epub 2022 Jun 17.

Research Unit for General Practice, Aarhus, Denmark.

Objective: To explore health care use in the 12 months preceding a diagnosis of rheumatoid arthritis (RA) in Denmark.

Methods: We conducted a population-based cohort study using data from national registries. Every patient diagnosed with RA in 2014-2018 was matched to ten reference individuals without RA from the Danish background population. Read More

View Article and Full-Text PDF

Rapid Spontaneous Total Fusion of Neuropathic Arthropathy of the Wrist After Limited Intercarpal Arthrodesis: A Case Report and Brief Literature Review.

Front Surg 2022 30;9:771896. Epub 2022 May 30.

Department of Hand Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.

Background: Previous reports on the treatment of neuropathic arthropathy of the wrist were generally conservative, with few case reports of treatment with osteoarticular surgery.

Case Presentation: A 25-year-old right-handed male complained of unpainful swelling of the dorsal aspect of his right wrist for 3 years. He was at that time diagnosed with synovitis and radiocarpal arthritis. Read More

View Article and Full-Text PDF

Ganoderic acid A improves osteoarthritis by regulating RANKL/OPG ratio.

Chem Biol Drug Des 2022 Jun 16. Epub 2022 Jun 16.

The Third Department of Orthopaedics, Cangzhou Central Hospital, 16 Xinhua West Road, Cangzhou, Heibei Province, 061001, China.

Ganoderma mushrooms have been used to treat rheumatoid arthritis (RA) in East Asia. Whether Ganoderic acid A (GAA), the natural product extracted from Ganoderma, could be utilized to alleviate osteoarthritis (OA) is investigated in this study. Destabilization of the medial meniscus (DMM) model was constructed to reveal the in vivo effect of GAA. Read More

View Article and Full-Text PDF

Tendons and Tendon Sheaths of the Hand - An Update on MRI.

Rofo 2022 Jun 15. Epub 2022 Jun 15.

Department of Radiology, University Hospital Wuerzburg, Germany.

Background:  The tendons of the hand run in close proximity to each other and within retinacular tunnels adjacent to articular joints, while forming intersections in characteristic locations. The enclosing tendon sheaths are often sites of systemic or infectious inflammation.

Method:  This review article outlines the different entities of tendon and tendon sheath pathology and their manifestation in the hands. Read More

View Article and Full-Text PDF

Outcomes of Flexor Tendon Repair in Patients With Concurrent Neurovascular Injuries of Multiple Digits in Zone 1.

Ann Plast Surg 2022 May 30. Epub 2022 May 30.

From the Department of Orthopedic Surgery, Regional Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.

Purpose: We treated several patients with multiple flexor (flexor digitorum profundus; FDP) injuries accompanied by injuries to the digital nerve or vessels around the distal interphalangeal crease (zone 1). Here, we retrospectively report the outcomes and review the literature.

Materials And Methods: Between January 2010 and December 2018, 16 patients who met the study inclusion criteria were investigated. Read More

View Article and Full-Text PDF

High prevalence of chondrocalcinosis and frequent comorbidity with calcium pyrophosphate deposition disease in patients with seronegative rheumatoid arthritis.

RMD Open 2022 Jun;8(2)

Ruhr University Bochum, Bochum, Germany

Background: The crystal-induced calcium pyrophosphate deposition disease (CPPD) clinically appearing as pseudogout differs from the mere radiographic finding of chondrocalcinosis (CC) but may cause symptoms resembling rheumatoid arthritis (RA).

Objective: To study the prevalence of CPPD and CC in rheumatic diseases focusing on differences between seropositive and seronegative RA.

Patients And Methods: In a retrospective study design, we analysed records and radiographs of consecutive new patients presenting to our centre between January 2017 and May 2020. Read More

View Article and Full-Text PDF

Characteristics of Intermetatarsal Angle Between the Second and Fifth Metatarsals (M2-M5A) in the Rheumatoid Foot.

Cureus 2022 May 8;14(5):e24831. Epub 2022 May 8.

Orthopaedic Surgery, National Hospital Organization, Osaka Minami Medical Center, Kawachinagano, JPN.

Background: Increasing of intermetatarsal angle between the first and second metatarsals (M1-M2A) has been reported as a risk factor for recurrence of hallux valgus (HV) deformity, on the other hand, increasing of intermetatarsal angle between the second and fifth metatarsals (M2-M5A) has been reported as a risk factor for resubluxation of the metatarsophalangeal (MTP) joint of the lesser toe after rheumatoid forefoot surgery. In this study, parameters related to increasing M2-M5A were investigated, as compared with M1-M2A and M1-M5A.

Methods: Radiographic parameters including M1-M2A, M1-M5A, and M2-M5A were retrospectively evaluated for 119 lower limbs from 68 patients with rheumatoid arthritis (RA). Read More

View Article and Full-Text PDF

Concurrence of Rheumatoid Arthritis and Ankylosing Spondylitis: Analysis of Seven Cases and Literature Review.

Case Rep Rheumatol 2022 28;2022:8500567. Epub 2022 May 28.

San Pedro Hospital, Logroño, La Rioja, Spain Rheumatology Department.

Introduction: The association of rheumatoid arthritis (RA) and ankylosing spondylitis (AS) in a single patient is a rarely described phenomenon. AS and RA are conditions that can have a high impact on the morbidity and mortality of patients.

Methods: We described the clinical, epidemiological, analytical, and radiological characteristics of 81 patients with concomitant diagnosis of rheumatoid arthritis (RA) and ankylosing spondylitis (AS). Read More

View Article and Full-Text PDF

Total Wrist Arthroplasty with Integra Freedom Implants: A Pilot Study with a New Evaluation System.

Indian J Orthop 2022 Jun 22;56(6):1040-1047. Epub 2022 Apr 22.

Hand Surgery Department, Ospedale San Paolo, Via Genova 30, 17100 Savona, Italy.

Introduction: Recent innovations in wrist arthroplasty implants have led to remarkable improvements in terms of results with improved stability and preservation of bone stock. Despite the advances in such implants, poor outcomes and frequent complications still affect this procedure, not allowing a wider use of this treatment in wrist arthritis.The purpose of this study is to assess the preliminary mid-term results of a Wrist Arthroplasty System (Freedom, Integra Lifesciences, Princeton, USA) in patients with rheumatoid arthritis or secondary osteoarthritis of the wrist and to propose a new classification system. Read More

View Article and Full-Text PDF

Validity and Reliability of the Turkish Version of the DASH-TR Questionnaire in Rheumatoid Arthritis Patients, Based on Rasch Analysis.

Int J Rheum Dis 2022 Jun 6. Epub 2022 Jun 6.

Department of Rheumatology, Medical Faculty of Pamukkale University, Denizli, Turkey.

Aim: This study aimed to examine the validity and reliability of the Turkish version of the Disabilities of the Arm, Shoulder and Hand Problems (DASH-TR) questionnaire in rheumatoid arthritis (RA) using the Rasch analysis.

Method: A total 97 individuals (13 men, 84 women; mean age:51.99 ± 11. Read More

View Article and Full-Text PDF

The Role of M1/M2 Macrophage Polarization in Rheumatoid Arthritis Synovitis.

Front Immunol 2022 19;13:867260. Epub 2022 May 19.

Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine and Specialties (DIMI), University of Genova, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Martino Polyclinic Hospital, Genoa, Italy.

Innate and adaptive immunity represent a harmonic counterbalanced system involved in the induction, progression, and possibly resolution of the inflammatory reaction that characterize autoimmune rheumatic diseases (ARDs), including rheumatoid arthritis (RA). Although the immunopathophysiological mechanisms of the ARDs are not fully clarified, they are often associated with an inappropriate macrophage/T-cell interaction, where classical (M1) or alternative (M2) macrophage activation may influence the occurrence of T-helper (Th)1 or Th2 responses. In RA patients, M1/Th1 activation occurs in an inflammatory environment dominated by Toll-like receptor (TLR) and interferon (IFN) signaling, and it promotes a massive production of pro-inflammatory cytokines [i. Read More

View Article and Full-Text PDF

Surgical Outcomes, Trends, and Risk Factors of Distal Triceps Repairs.

Hand (N Y) 2022 Jun 6:15589447221095114. Epub 2022 Jun 6.

Department of Orthopaedic Surgery and Rehabilitation Medicine, University of Chicago, Chicago, IL, USA.

Background: Distal triceps ruptures are rare, and complete ruptures are commonly treated with surgery. Studies of patients in small cohorts with distal triceps tear have reported outcomes and risk factors; however, large-scale data are scant. This study seeks to determine current trends, outcomes, and risk factors of distal triceps tears. Read More

View Article and Full-Text PDF

An investigation of the relationship between rheumatological diseases and soluble receptor for advanced glycation end products.

Eur Rev Med Pharmacol Sci 2022 May;26(10):3450-3455

Department of Internal Medicine, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey.

Objective: Soluble receptor for advanced glycation end products (sRAGE) is one of the forms of RAGE. It is a trap receptor that has a role in inhibiting pro-inflammatory processes that will occur with the combination of RAGE and its ligands. Our study aims to examine the level of sRAGE in rheumatological inflammatory diseases and its relationship with these diseases. Read More

View Article and Full-Text PDF

Radiocarpal Fusion: Indications, Technique, and Modifications.

J Hand Surg Am 2022 May 28. Epub 2022 May 28.

Department of Orthopaedics, Warren Alpert School of Medicine, Brown University, Providence, RI.

Degenerative disorders of the wrist may affect isolated joints and inhibit normal functions of the wrist secondary to pain and stiffness. These processes that affect only the radiocarpal joint may be secondary to posttraumatic osteoarthritis, primary osteoarthritis, or rheumatoid arthritis. Radiocarpal wrist arthrodesis may help preserve some of the native wrist kinematics while alleviating pain and improving the range of motion. Read More

View Article and Full-Text PDF

[CME Rheumatology 26: Rheumatological Cases].

Praxis (Bern 1994) 2022 ;111(7):421-427

Spinale Chirurgie, Universitätsspital Basel, Basel, Schweiz.

CME Rheumatology 26: Rheumatological Cases Special rheumatological cases are illustrated using various examples. On the one hand we present differential diagnoses and causes of a "Baker's cyst", on the other hand a case of involvement of the cervical spine in rheumatoid arthritis. Usually, the medical history and precise clinical examination will lead us in the right diagnostic direction. Read More

View Article and Full-Text PDF

Monitoring of patients with rheumatoid arthritis by indocyanine green (ICG)-enhanced fluorescence optical imaging treated with anti-TNFα therapy.

Arthritis Res Ther 2022 05 21;24(1):117. Epub 2022 May 21.

Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, 10117, Berlin, Germany.

Background: Fluorescence optical imaging (FOI) enables visualisation of inflammation in both hands in rheumatoid arthritis (RA).

Objective: To investigate the usefulness of FOI in treatment monitoring under anti-TNFα therapy with certolizumab pegol (CZP) in patients with RA in comparison to clinical and laboratory outcome parameters.

Methods: CZP-naïve patients with RA were eligible for this open-label study with an observational period of 52 weeks. Read More

View Article and Full-Text PDF

Potential therapeutic application of biophenols - plants secondary metabolites in rheumatoid arthritis.

Crit Rev Food Sci Nutr 2022 May 20:1-19. Epub 2022 May 20.

Natural Product Drug Discovery Laboratory, Department of Pharmaceutical Science, Shalom Institute of Health and Allied Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, Uttar Pradesh, India.

Rheumatoid arthritis (RA) is a chronic autoimmune disease showed that persistent inflammation in the joints, induces the cartilage destruction, bone erosion, and leukocyte infiltration in the synovium. RA mostly affects the joints of hands, feet, wrists, ankles, and knees. Each year, approximately 20-40 new cases are reported per lac population and the disease affects women more than men. Read More

View Article and Full-Text PDF

Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial.

Nat Med 2022 Jun 19;28(6):1256-1268. Epub 2022 May 19.

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Patients with rheumatoid arthritis (RA) receive highly targeted biologic therapies without previous knowledge of target expression levels in the diseased tissue. Approximately 40% of patients do not respond to individual biologic therapies and 5-20% are refractory to all. In a biopsy-based, precision-medicine, randomized clinical trial in RA (R4RA; n = 164), patients with low/absent synovial B cell molecular signature had a lower response to rituximab (anti-CD20 monoclonal antibody) compared with that to tocilizumab (anti-IL6R monoclonal antibody) although the exact mechanisms of response/nonresponse remain to be established. Read More

View Article and Full-Text PDF

Total-Body F-FDG PET/CT in Autoimmune Inflammatory Arthritis at Ultra-Low Dose: Initial Observations.

J Nucl Med 2022 May 19. Epub 2022 May 19.

University of California Davis, United States.

Autoimmune inflammatory arthritides (AIA), such as psoriatic arthritis (PsA) and rheumatoid arthritis (RA), are chronic systemic conditions that affect multiple joints of the body. Recently, total-body (TB) PET/CT scanners have become available that exhibit superior technical characteristics (total-body coverage, geometric sensitivity) that could benefit AIA evaluation, compared to conventional PET/CT systems. The objectives of this work were to (1) assess the performance of an ultra-low-dose, F-FDG TB-PET/CT acquisition protocol for evaluating systemic joint involvement in AIA; and (2) report the association of TB-PET/CT measures with joint-by-joint rheumatologic examination and standardized rheumatologic outcome measures. Read More

View Article and Full-Text PDF

The "Hand as Foot" figural teaching method in the rheumatoid arthritis.

Asian J Surg 2022 May 13. Epub 2022 May 13.

Department of Pediatrics, Affiliated Hospital of Inner Mongolia Medical University, No. 1, Tongdao North Street, Huimin District, Hohhot, Inner Mongolia, 010050, China.

View Article and Full-Text PDF

Understanding prescribed dose in hand strengthening exercise for rheumatoid arthritis: A secondary analysis of the SARAH trial.

Musculoskeletal Care 2022 May 16. Epub 2022 May 16.

Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, UK.

Objective: 1) To identify therapist or participant characteristics associated with prescribed dose of hand strengthening exercise in adults with rheumatoid arthritis and 2) To determine the impact of dose prescribed on outcome (hand function and grip strength).

Methods: Overall dose was calculated using area under the curve (AUC). Analysis 1 assessed the association between therapist professional background, therapist grade, baseline participant physical and psychological characteristics and prescribed dose. Read More

View Article and Full-Text PDF

Primary repair of extensor pollicis longus rupture after volar locking plating for distal radial fracture.

Hand Surg Rehabil 2022 May 13. Epub 2022 May 13.

Department of Orthopedic Surgery, Regional Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Chungnam National University School of Medicine, 266 Munwha-ro, Jung-Gu, Daejeon, South Korea.

We presumed that primary repair would be possible if the extensor pollicis longus (EPL) rupture after volar locking plating (VLP) for distal radius fracture (DRF) was diagnosed earlier. Thus, five cases of EPL ruptures were resolved via primary repair rather than extensor indicis proprius (EIP) transfer, so we reported the clinical outcomes of at least 2 years follow-up since EPL repair. Of 588 consecutive patients with the fractures treated between January 2016 and December 2019, 501 who met out inclusion/exclusion criteria were initially investigated. Read More

View Article and Full-Text PDF

The value of ultrasound and magnetic resonance imaging scoring systems in explaining handgrip strength and functional impairment in rheumatoid arthritis patients: a pilot study.

Radiol Med 2022 Jun 14;127(6):652-663. Epub 2022 May 14.

Dipartimento di Scienze Radiologiche, Ospedali Riuniti, Università Politecnica delle Marche, Ancona, Italy.

Purpose: The goal of this study is to investigate the relationship between joint inflammation and damage of the wrists and hands, measured by semiquantitative ultrasound and magnetic resonance imaging scoring systems, with functional disability and handgrip strength (HGs).

Materials And Methods: Consecutive adult RA patients with active disease, as defined by a Disease Activity Score 28 joints C-reactive protein (DAS28-CRP) > 3.2, underwent a cross-sectional evaluation comprehensive of a clinimetric assessment, an HGs evaluation, an ultrasound assessment aimed at calculating the UltraSound-CLinical ARthritis Activity (US-CLARA), and a magnetic resonance imaging scored according to the modified Simplified Rheumatoid Arthritis Magnetic Resonance Imaging Score (mod SAMIS). Read More

View Article and Full-Text PDF