7,337 results match your criteria Rheumatoid Arthritis Hands

High-intensity interval training can improve hand grip strength, inspiratory muscle, and quality of life in systemic sclerosis subjects.

Reumatologia 2021 27;59(2):98-103. Epub 2021 Apr 27.

Faculty of Medicine, Maranatha Christian University, Bandung, Indonesia.

Introduction: Systemic sclerosis/scleroderma (SSc) is a chronic autoimmune disease with connective tissue, multi-organ, and multisystem involvement. The disease has three main characteristics, namely vasculopathy, fibrosis, and autoimmunity. The effect of high-intensity interval training (HIIT) in aerobic exercise on other rheumatic diseases has been studied, for example in patients with rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA). Read More

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Intermanual Transfer Effects on Performance Gain Following Dominant Hand Training in Community-Dwelling Healthy Adults: A Preliminary Study.

J Multidiscip Healthc 2021 30;14:1007-1016. Epub 2021 Apr 30.

Rehabilitation Research Chair, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

Purpose: This study aimed to evaluate the intermanual transfer effects of dominant hand training on the functional task of the untrained hand.

Methods: Fifty community-dwelling healthy adults (mean age, 23.4 ± 2. Read More

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Quality Indicators for Evaluating the Health Care of Patients with Rheumatoid Arthritis: a Korean Expert Consensus.

J Korean Med Sci 2021 May 3;36(17):e109. Epub 2021 May 3.

Division of Rheumatology, Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea.

Background: There is increasing interest in the quality of health care and considerable efforts are being made to improve it. Rheumatoid arthritis (RA) is a disease that can result in favorable outcomes when appropriate diagnosis and treatment are provided. However, several studies have shown that RA is often managed inappropriately. Read More

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Reported disability in relation to observed activity limitation, grip strength and physical function in women and men with rheumatoid arthritis.

BMC Rheumatol 2021 May 3;5(1):13. Epub 2021 May 3.

Department of Medicine, Division of Gastroenterology and Rheumatology, Karolinska Institutet, Huddinge, Stockholm, Sweden.

Background: The self-reported Health Assessment Questionnaire (HAQ) is specifically designed to assess disability in arthritic patients. In many studies women report higher functional disability than men. The reasons for this difference are suggested to be multifactorial. Read More

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Atlantoaxial Stabilization by Posterior C1 and C2 Screw-Rod Fixation for Various Pathologies: Case Series and Comprehensive Review of Literature.

J Neurosci Rural Pract 2021 Apr 3;12(2):228-235. Epub 2021 Mar 3.

Department of Neurosurgery, Government Medical College, Kozhikode, Kerala, India.

We retrospectively analyzed atlantoaxial dislocation (AAD) of various pathologies, namely, rheumatoid arthritis (RA), os odontoideum, and trauma. Various techniques were discussed in relation to C1-C2 stabilization. The study aims to share our clinical experience in a series of six cases of C1-C2 instability that underwent posterior C1-C2 fusion, with free hand technique and limited fluoroscopy. Read More

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Utilizing ultrasound findings of a single indicator joint to assess non-systemic juvenile idiopathic arthritis.

Pediatr Rheumatol Online J 2021 Apr 29;19(1):60. Epub 2021 Apr 29.

Department of Pediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

Background: Musculoskeletal ultrasound (MSUS) has been used worldwide in adult patients with rheumatoid arthritis (RA) but is beginning to play an increasing role in patients with juvenile idiopathic arthritis (JIA). The aim of this study was to investigate the application of MSUS findings of a single indicator joint in JIA to assess the disease activity and classify disease subtype.

Methods: Thirty-five non-systemic JIA patients with a total of 62 visits were retrospectively recruited in this study. Read More

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Long-Term Results of the Modular Physiological Wrist Prosthesis (MPW) in Patients with Inflammatory Diseases.

Life (Basel) 2021 Apr 18;11(4). Epub 2021 Apr 18.

Department of Trauma, Hand and Reconstructive Surgery, University Hospital Giessen, 35392 Giessen, Germany.

The wrist is among the predilection sites of over 90% of cases of rheumatoid arthritis (RA). In advanced cases, total wrist arthroplasty (TWA) is an alternative to arthrodesis. The aim of this study is to present the long-term results of the modular physiological wrist prosthesis (MPW) and to match them in context with the results of a standard population survey. Read More

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[CME Rheumatology 23: Rheumatoid Arthritis Following COVID-19/SARS-CoV-2 Infection].

Praxis (Bern 1994) 2021 Apr;110(6):293-297

Klinik für Rheumatologie, Universitätsspital Zürich, Zürich.

CME Rheumatology 23: Rheumatoid Arthritis Following COVID-19/SARS-CoV-2 Infection Individuals with rheumatic diseases, especially those on immuno-modulating treatment, have an increased risk of infection. On the other hand, it is known that viral infections may be a cause for acute arthralgias and of arthritis. We present in the following a case of ACPA-positive and RF-positive rheumatoid arthritis after an acute COVID-19/SARS-CoV-2 infection and discuss the possible association with the infection. Read More

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Total Elbow Arthroplasty: A Descriptive Analysis of 170 Patients From a United States Integrated Health Care System.

J Hand Surg Am 2021 Apr 22. Epub 2021 Apr 22.

Department of Orthopedic Surgery, Southern California Permanente Medical Group, Harbor City, CA.

Purpose: Total elbow arthroplasty (TEA) can be used, with varying degrees of success, for the treatment of rheumatoid arthritis, osteoarthritis, and distal humerus fractures and their sequelae in elderly patients. Some of the largest studies of TEA have included data from more than 20 years ago and may not reflect the current practice of TEA. We sought to describe a modern cohort of patients who underwent TEA in a United States integrated health care system. Read More

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A Novel Fluorescence Optical Imaging Scoring System for Hand Synovitis in Rheumatoid Arthritis - validity and agreement with ultrasound.

Rheumatology (Oxford) 2021 Apr 23. Epub 2021 Apr 23.

Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark.

Objectives: To develop and validate a new semiquantitative Fluorescence Optical Imaging (FOI) scoring system - the FOI Enhancement-Generated rheumatoid arthritis (RA) Score (FOIE-GRAS) for synovitis assessment in the hand.

Methods: The development of FOIE-GRAS was based on consensus of 4 experts in musculoskeletal imaging. Forty-six RA patients, eligible for treatment intensification and with ≥1 clinically swollen joint in the hands and 11 healthy controls were included. Read More

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Efficacy and safety of hydroxychloroquine in osteoarthritis: a systematic review and meta-analysis of randomized controlled trials.

Korean J Intern Med 2021 Apr 22. Epub 2021 Apr 22.

Department of Musculoskeletal Health and Disease, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia.

Background/aims: Conventional disease-modifying anti-rheumatic drugs have been trialed in osteoarthritis (OA). Hydroxychloroquine (HCQ), which has shown its effectiveness in rheumatoid arthritis, has been trialed for the treatment of OA; however, its efficacy and safety remain unclear. This systematic review and meta-analysis evaluate efficacy and safety of HCQ for the treatment of OA. Read More

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The role of PET in a clinically silent and ultrasound negative synovitis in the course of rheumatoid arthritis - a case report.

Reumatismo 2021 Apr 19;73(1):64-66. Epub 2021 Apr 19.

Rheumatology Centre and Dipartimento Scienze Cliniche e Biologiche, Università degli Studi di Torino, Turin.

We present a case report of a rheumatoid arthritis patient, who underwent a PET scan, which revealed inflammation of multiple joints, which was missed by both physical and ultrasound examinations. A 55-year old woman with a long-term rheumatoid arthritis, who had undergone arthroplasty of the left knee in the past, consulted with the rheumatologist for pain in the left knee. The physical examination revealed signs of inflammation in the left knee and right elbow. Read More

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Baricitinib: From Rheumatoid Arthritis to COVID-19.

J Clin Pharmacol 2021 Apr 18. Epub 2021 Apr 18.

Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Baricitinib is a JAK1/2 inhibitor first approved for treating moderate to severe rheumatoid arthritis but later showed considerable efficacy in the control of exaggerated inflammatory responses that occur in a wide range of diseases. There is a growing body of evidence, obtained from clinical trials and case reports, demonstrating clinical and paraclinical improvement in patients following administration of baricitinib including rheumatoid arthritis, systemic lupus erythematosus, psoriasis, atopic dermatitis, alopecia areata, interferon-mediated auto-inflammatory diseases, graft versus host disease, diabetic kidney disease, and recently, coronavirus disease-19. However, despite overall encouraging results, many adverse effects have been observed in baricitinib-treated patients ranging from simple infections to increased risk of malignancies, particularly in long-term use. Read More

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A hand exercise mobile app for people with rheumatoid arthritis in Turkey: design, development and usability study.

Rheumatol Int 2021 Jun 18;41(6):1151-1160. Epub 2021 Apr 18.

Centre for Rehabilitation Research, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, UK.

To design and develop a smartphone application for a structured hand exercise programme for patients with rheumatoid arthritis (RA) in Turkey and to test its usability. We followed a two-stage process: (1) Design and Development and (2) Usability testing. In stage 1, we used a qualitative user-centered design approach. Read More

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Region specificity of rheumatoid foot symptoms associated with ultrasound-detected synovitis and joint destruction.

Mod Rheumatol 2021 Apr 14:1-28. Epub 2021 Apr 14.

Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Objectives: We aimed to clarify the clinical implication of ultrasound (US)-detected foot joint inflammation in tightly controlled patients with rheumatoid arthritis (RA).

Methods: We evaluated bilateral foot joints (second to fifth metatarsophalangeal joints of forefoot; tarsometatarsal, cuneonavicular and midtarsal joints of midfoot) of 430 RA patients for synovitis using Power Doppler (PD) imaging by US. We made a cross-sectional and a 3-year longitudinal analysis about the associations of US-detected synovitis with clinical, laboratory and radiographic data as well as foot-specific outcomes using a self-administered foot evaluation questionnaire (SAFE-Q). Read More

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Bone Erosions Detected by Ultrasound Are Prognostic for Clinical Arthritis Development in Patients With ACPA and Musculoskeletal Pain.

Front Med (Lausanne) 2021 23;8:653994. Epub 2021 Mar 23.

Department of Rheumatology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

Anti-citrullinated protein antibodies (ACPA) often precede onset of rheumatoid arthritis (RA) by years, and there is an urgent clinical need for predictors of arthritis development among such at-risk patients. This study assesses the prognostic value of ultrasound for arthritis development among ACPA-positive patients with musculoskeletal pain. We prospectively followed 82 ACPA-positive patients without clinical signs of arthritis at baseline. Read More

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Effects of Orem's Self-Care Model of Nursing on Hand Symptoms and Life Activities in Geriatric Individuals Diagnosed with Rheumatoid Arthritis: A Pilot Study.

Res Theory Nurs Pract 2021 Apr 7. Epub 2021 Apr 7.

Nursing Department, Eskisehir Osmangazi University, Meselik Kampus, Eskisehir.

Background And Purpose: According to Orem's self-care deficit theory, when patients cannot meet their care needs, they need nursing systems for maintaining their health. Nursing care for elderly patients with rheumatoid arthritis (RA) should be based on maintaining self-care. This study aims to determine the effects of Orem's self-care model of nursing care given to geriatric patients with RA on hand symptoms, life activities, and hand pain. Read More

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Universal 2™ total wrist arthroplasty: A single-surgeon 6.5-year follow-up study of 22 prostheses.

Hand Surg Rehabil 2021 Apr 1. Epub 2021 Apr 1.

Department of Orthopaedic and Traumatology, Miguel Servet University Hospital, Paseo Isabel la Católica, 1-3, 50009 Zaragoza, Spain.

Total wrist arthroplasty remains controversial, with the few studies undertaken being heterogeneous and having low patient numbers. This prospective study involved 22 Universal 2™ total wrist prostheses implanted by the same surgeon between 2003 and 2017. There were 13 women and nine with an average age of 56 (42-69. Read More

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Structural damage in rheumatoid arthritis assessed by musculoskeletal ultrasound: A systematic literature review by the Structural Joint Damage Task Force of the OMERACT Ultrasound Working Group.

Semin Arthritis Rheum 2021 Mar 21. Epub 2021 Mar 21.

Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, 18-20 Währinger Gürtel, Vienna, Austria. Electronic address:

Objectives: To identify and synthesize the evidence for the use and measurement properties of musculoskeletal ultrasound in assessing structural joint damage in patients with rheumatoid arthritis (RA).

Methods: A systematic literature search (SLR) of the PubMed, Embase and Cochrane Library was performed. Original articles were included published in English reporting on ultrasound of bone erosion, cartilage damage and the measurement properties of ultrasound according to the OMERACT filter 2. Read More

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Effect of Anti-Rheumatic Treatment on the Periodontal Condition of Rheumatoid Arthritis Patients.

Int J Environ Res Public Health 2021 03 4;18(5). Epub 2021 Mar 4.

Department of Internal Medicine and Rheumatology, Martini Hospital Groningen, Van Swietenplein 1, 9728 NT Groningen, The Netherlands.

Periodontitis, a bacterial-induced infection of the supporting soft and hard tissues of the teeth (the periodontium), is common in patients with rheumatoid arthritis (RA). As RA and periodontitis underlie common inflammatory pathways, targeting the progression of RA might mediate both periodontitis and RA. On the other hand, patients with RA on immunosuppressive medication have an increased risk of infection. Read More

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Structural and Functional Changes of Hands and Legs in Early Rheumatoid Arthritis.

Medicina (Kaunas) 2021 Mar 28;57(4). Epub 2021 Mar 28.

Institute of Clinical Medicine, University of Tartu, L. Puusepa 8, 51014 Tartu, Estonia.

The aim of this study was to assess if there are structural and functional changes of hands and legs already in early rheumatoid arthritis (ERA), compared with the population-based control group. Additionally, we aimed to identify if the changes are symmetrical in hands and legs and if there are factors that are associated with these changes. The study was conducted, and, thus far, the results have been controversial. Read More

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Necrotic Ulceration of the Hand Case Review: Think Beyond Infection.

J Emerg Nurs 2021 Mar 29. Epub 2021 Mar 29.

Neutrophilic dermatosis of the dorsal hands is a rare neutrophilic dermatosis that can be associated with inflammatory bowel disease, rheumatoid arthritis, and underlying malignancies. The occurrence of trauma as an initiating factor and its early features of pain and inflammation followed by blistering or ulceration mean that it can be mistaken for necrotizing infection. Neutrophilic dermatosis of the dorsal hands should be considered in all patients who present with such features confined to the back of the hands, particularly those with negative microbiological results or lack of response to antibiotic therapy. Read More

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[Atypical arthritis of the hands : Collagenosis-part 2].

Matthias Bollow

Radiologe 2021 May 1;61(5):470-482. Epub 2021 Apr 1.

Klinik für diagnostische und interventionelle Radiologie, Augusta-Kranken-Anstalt Bochum, Bergstraße 26, 44791, Bochum, Deutschland.

Background: Progressive systemic scleroderma (PSS) and mixed connective tissue disease (MCTD) represent vasculitic autoimmune diseases from the group of collagenoses with manifestations in various organ systems such as the skin, the internal organs and the joints.

Objective: To present the atypical arthritis patterns of the hands in PSS and MCTD that differ from those in rheumatoid arthritis (RA) and psoriatic arthritis (PsA) in the context of clinical and serologic findings and in consideration of the classification of PSS and MCTD.

Materials And Methods: Narrative review based on the current literature on the subject from the radiological and rheumatological point of view. Read More

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Therapeutic Potential of Digital Nerve Block in Rheumatoid Arthritis Patients: A Clinical and Sonographic Prospective Study.

Clin J Pain 2021 Jun;37(6):413-420

Department of Rheumatology and Rehabilitation, Sohag University Hospital, Sohag.

Background: This study attempted to test the effectiveness of digital nerve block (DNB) in active rheumatoid arthritis (RA) joints with respect to local disease control.

Methods: The study included 83 RA patients aged 18 years or above and diagnosed, after American College of Rheumatology/European League Against Rheumatism criteria 2010, with bilateral proximal interphalangeal (PIP) arthritis. PIPs were examined by European League Against Rheumatism-outcome measures in rheumatoid arthritis clinical trials scoring system at 0, 2, and 8 weeks. Read More

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[Atypical arthritis of the hands : Collagenosis-part 1].

Matthias Bollow

Radiologe 2021 May 29;61(5):458-469. Epub 2021 Mar 29.

Ruhr-Universität Bochum, Bochum, Deutschland.

Background: Systemic lupus erythematosus (SLE) is a gynecotropic autoimmune vasculitis with manifestations in various organ systems including the skin, internal organs, and joints.

Objective: Presentation of the atypical arthritis patterns of the hands in SLE as the most common autoimmunologic rheumatologic disease from the group of collagenoses in the context of clinical and serological findings and considering the classification criteria of the American College of Rheumatology compared to rheumatoid arthritis (RA) and psoriatic arthritis (PsA).

Materials And Methods: Narrative review based on the current literature on the subject from a radiological and rheumatological point of view. Read More

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Evaluation of the Structural Validity of the Work Instability Scale Using the Rasch Model.

Arch Rehabil Res Clin Transl 2021 Mar 13;3(1):100103. Epub 2021 Jan 13.

School of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada.

Objective: To use Rasch analysis to examine the measurement properties of the 23-item version of the Work Instability Scale (WIS-23) in a sample of worker compensation claimants with upper extremity disorders.

Design: Secondary data analysis on the data retrieved from a cross-sectional study.

Setting: Tertiary care hospital. Read More

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Heterogenous bone response to biologic DMARD therapies in rheumatoid arthritis patients and their relationship to functional indices.

Scand J Rheumatol 2021 Mar 29:1-10. Epub 2021 Mar 29.

McCaig Institute for Bone and Joint Health, Cumming School of Medicine, University of Calgary, Calgary, Canada.

: Previous studies of high-resolution peripheral quantitative computed tomography (HR-pQCT) imaging of hand joints in patients with rheumatoid arthritis (RA) have suggested that erosion healing may occur. Our objective was to examine changes in erosion volume, joint space width (JSW), bone mineral density (BMD), and bone remodelling, and their association with clinical outcomes and measures of patient hand function.: We examined 48 patients who achieved a good response to a newly initiated biologic therapy. Read More

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Prevalence and trajectory of erosions, synovitis, and bone marrow edema in feet of patients with early rheumatoid arthritis.

Clin Rheumatol 2021 Mar 18. Epub 2021 Mar 18.

Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

Despite erosions being as prevalent in feet as in hands in patients with rheumatoid arthritis (RA), their development in relation to synovitis and bone marrow edema (BME) have mainly been studied in hands. This study examines the prevalence and longitudinal trajectory of erosions, BME, and synovitis in metatarsophalangeal joints (MTPJs) in patients with early RA over 2 years of treatment. We also describe correlations between erosions, synovitis, and BME at the joint level. Read More

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Innate Lymphoid Cells and Adaptive Immune Cells Cross-Talk: A Secret Talk Revealed in Immune Homeostasis and Different Inflammatory Conditions.

Vijay Kumar

Int Rev Immunol 2021 Mar 18:1-35. Epub 2021 Mar 18.

Children's Health Queensland Clinical Unit, School of Clinical Medicine, Faculty of Medicine, Mater Research, University of Queensland, St Lucia, Brisbane, Queensland, Australia.

The inflammatory immune response has evolved to protect the host from different pathogens, allergens, and endogenous death or damage-associated molecular patterns. Both innate and adaptive immune components are crucial in inducing an inflammatory immune response depending on the stimulus type and its duration of exposure or the activation of the primary innate immune response. As the source of inflammation is removed, the aggravated immune response comes to its homeostatic level. Read More

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