1,690 results match your criteria Rheumatic diseases clinics of North America[Journal]


The Interface Between Digital Health and Rheumatology.

Rheum Dis Clin North Am 2019 May;45(2):xv-xvi

Division of Infectious Diseases, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road, Mail Code GH104, Portland, OR 97239-3098, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rdc.2019.02.001DOI Listing

Technology and Big Data in Rheumatology.

Rheum Dis Clin North Am 2019 May;45(2):xiii-xiv

Division of Rheumatology, Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, 1545 Calmar Court Los Angeles, CA 90024, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rdc.2019.02.002DOI Listing
May 2019
1 Read

Project ECHO: Telehealth to Expand Capacity to Deliver Best Practice Medical Care.

Rheum Dis Clin North Am 2019 May 8;45(2):303-314. Epub 2019 Mar 8.

Project ECHO, University of New Mexico Health Sciences Center, 1650 University Boulevard NE Albuquerque, NM 87102, USA.

Project ECHO (Extension for Community Healthcare Outcomes) was developed at the University of New Mexico Health Sciences Center to educate health care professionals in underserved communities to treat chronic complex diseases, allowing patients to receive better care, closer to home, with greater convenience, and at lower cost than referral to a specialty center. Videoconferencing technology is used to create learning networks, with case-based discussions as the primary method of education. The 3-year experience of Bone Health TeleECHO, a strategy to improve the care of osteoporosis and reduce the large treatment gap, is discussed. Read More

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http://dx.doi.org/10.1016/j.rdc.2019.01.003DOI Listing
May 2019
3 Reads

Imaging in the Mobile Domain.

Authors:
Paul Bird

Rheum Dis Clin North Am 2019 May 8;45(2):291-302. Epub 2019 Mar 8.

University of New South Wales, Suite 4 Level 1, 19 Kensington Street, Kogarah, Sydney, New South Wales 2217, Australia. Electronic address:

This article outlines the current state of imaging software with an emphasis on mobile sharing of images and mobile sharing of imaged data. The second portion focuses on the mobility of imaging design devices, highlighting the accessibility and the wider application of mobile devices. Read More

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http://dx.doi.org/10.1016/j.rdc.2019.01.002DOI Listing

Tools and Methods for Real-World Evidence Generation: Pragmatic Trials, Electronic Consent, and Data Linkages.

Rheum Dis Clin North Am 2019 May;45(2):275-289

Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA.

Real-world evidence requires use of new tools and methods to support efficient evidence generation. Among those tools are pragmatic trials, utilization of central/single institutional review board and electronic consent, and data linkages between diverse types of data sources (eg, a trial or registry to administrative claims or electronic medical record data). This article reviews these topics in the context of describing several exemplar use cases specific to rheumatology and provides perspective regarding both the promise and potential pitfalls in using these tools and approaches. Read More

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http://dx.doi.org/10.1016/j.rdc.2019.01.010DOI Listing
May 2019
1 Read

Using Health Information Technology to Support Use of Patient-Reported Outcomes in Rheumatology.

Rheum Dis Clin North Am 2019 May;45(2):257-273

Division of Rheumatology, University of California, San Francisco, San Francisco, CA, USA. Electronic address:

Technology can help health care providers understand their patients' experience of illness in a way that was previously impossible. Experience in using health information technology (IT) to capture this information through PROs within rheumatology suggests that careful attention to human centered design, including detailed workflow planning, consideration of patient and physician burden, integration into the health IT ecosystem, and delivering information to the right person at the right time are all important. Technology applications must be tested in diverse health systems and populations to ensure they are simple to interpret, useful for clinical decision making and effective in impacting outcomes. Read More

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http://dx.doi.org/10.1016/j.rdc.2019.01.007DOI Listing
May 2019
1 Read

Digital Patient Education and Decision Aids.

Rheum Dis Clin North Am 2019 May 8;45(2):245-256. Epub 2019 Mar 8.

Section of Rheumatology and Clinical Immunology, Division of Internal Medicine, Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Unit 1465, 1515 Holcombe Boulevard, Houston, TX 77030, USA. Electronic address:

New technologies can do more than just digitize health information; they can support multimedia platforms for patient education and health decision support. Technology can simplify the way health decisions are made by offering quick access to a vast amount of information that can be tailored to specific populations. Digital tools can increase knowledge and assist consumers in comparing health care alternatives. Read More

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http://dx.doi.org/10.1016/j.rdc.2019.01.001DOI Listing

Motivational Counseling and Text Message Reminders: For Reduction of Daily Sitting Time and Promotion of Everyday Physical Activity in People with Rheumatoid Arthritis.

Rheum Dis Clin North Am 2019 May;45(2):231-244

Centre for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Nordre Fasanvej 57, Hovedvejen 5, Frederiksberg 2000, Denmark; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen N, Denmark.

Most patients with rheumatoid arthritis tend to be physically inactive and spend more time in sedentary behaviors compared with the general population. This inactive lifestyle can lead to serious health consequences, for example, increased risk of cardiovascular disease. For this reason, there is an interest in increasing participation in physical activity in patients with rheumatoid arthritis. Read More

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http://dx.doi.org/10.1016/j.rdc.2019.01.005DOI Listing
May 2019
3 Reads

Patient-Reported Outcomes Measurement Information System Versus Legacy Instruments: Are They Ready for Prime Time?

Authors:
Vivian P Bykerk

Rheum Dis Clin North Am 2019 May;45(2):211-229

The Hospital for Special Surgery, Inflammatory Arthritis Center, Weill Cornell Medical College, 535 East 70th Street, New York, NY 10022, USA. Electronic address:

"Legacy" patient-reported outcome measures (PROs) have been used for decades; however, they have many limitations. The National Institutes of Health-funded PRO Measurement Information System (PROMIS) was developed to be a generic, flexible, precise, and reliable tool to measure core and additional domains of physical and emotional health and social well-being. Unlike Legacy PROs, PROMIS measures can be implemented across diseases, and use a common T-score metric-based scoring system derived using item response theory. Read More

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http://dx.doi.org/10.1016/j.rdc.2019.01.006DOI Listing
May 2019
4 Reads

Mobile Apps for Rheumatoid Arthritis: Opportunities and Challenges.

Rheum Dis Clin North Am 2019 May 8;45(2):197-209. Epub 2019 Mar 8.

Division of Rheumatology and Immunology, University of Nebraska Medical Center, 986270 Nebraska Medical Center, Omaha, NE 68198-6270, USA; FORWARD, The National Databank for Rheumatic Diseases, Wichita, KS, USA. Electronic address:

Mobile applications have the potential to improve health outcomes in patients with rheumatoid arthritis (RA). Whereas other chronic diseases such as diabetes and heart failure have a well-established presence in the mobile application realm, apps focused on RA are still in their infancy. This article presents an overview of the types of mobile apps that can be used for RA and discusses the opportunities and challenges associated with them. Read More

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http://dx.doi.org/10.1016/j.rdc.2019.01.011DOI Listing
May 2019
2 Reads

Patient Self-Management and Tracking: A European Experience.

Rheum Dis Clin North Am 2019 May;45(2):187-195

Department of Rheumatology, Bernhoven, Uden, the Netherlands; Radboud University Medical Center, Radboud Institute for Health Sciences, Scientific Institute for Quality of Healthcare (IQ Healthcare), Nijmegen, the Netherlands.

The shift from a paternalistic model of health care to a doctor-patient relationship in which the doctor and patient make shared decisions, requires an actively involved patient who takes responsibilities. This is why self-management by the patient with a chronic disease plays more of an important role in patient care nowadays; however, the degree of self-management varies per patient. To help stimulate patients in their self-management behavior, it is necessary to use an adequate tool, and to educate patients and health professionals. Read More

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http://dx.doi.org/10.1016/j.rdc.2019.01.008DOI Listing
May 2019
1 Read

Digital Interventions to Build a Patient Registry for Rheumatology Research.

Rheum Dis Clin North Am 2019 May;45(2):173-186

Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Faculty Office Tower, 510 20th Street South #834, Birmingham, AL 35294, USA.

This article aims to describe key issues, processes, and outcomes related to development of a patient registry for rheumatology research using a digital platform where patients track useful data about their condition for their own use while contributing to research. Digital interventions are effective to build a patient research registry for people with rheumatoid arthritis and other rheumatic and musculoskeletal diseases. ArthritisPower provides evidence of the value of digital interventions to build community support for research and to transform patient engagement and patient-generated data capture. Read More

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http://dx.doi.org/10.1016/j.rdc.2019.01.009DOI Listing
May 2019
2 Reads

Maximizing Engagement in Mobile Health Studies: Lessons Learned and Future Directions.

Rheum Dis Clin North Am 2019 May 8;45(2):159-172. Epub 2019 Mar 8.

Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

The widespread availability of smartphones, tablets, and smartwatches has led to exponential growth in the number of mobile health (mHealth) studies conducted. Although promising, the key challenge of all apps (both for research and nonresearch) is the high attrition rate of participants and users. Numerous factors have been identified as potentially influencing engagement, and it is important that researchers consider these and how best to overcome them within their studies. Read More

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http://dx.doi.org/10.1016/j.rdc.2019.01.004DOI Listing
May 2019
3 Reads

Best Practices and Challenges to the Practice of Rheumatologists.

Rheum Dis Clin North Am 2019 Feb;45(1):xv-xvi

Cedars Sinai Medical Center, David Geffen School of Medicine, University of California-Los Angeles, 8750 Wilshire Boulevard, Suite 350, Beverly Hills, CA 90211, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rdc.2018.10.001DOI Listing
February 2019
12 Reads
2.692 Impact Factor

Best Practices and Challenges to the Practice of Rheumatologists.

Rheum Dis Clin North Am 2019 Feb;45(1):xiii-xiv

Director, Division of Rheumatology, Professor of Medicine, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rdc.2018.10.002DOI Listing
February 2019
27 Reads

Challenges in Having an Infusion Center.

Rheum Dis Clin North Am 2019 Feb;45(1):87-100

NewView Medical Consulting, LLC, Santa Clarita, CA 91387, USA. Electronic address:

This article presents a comprehensive overview of the model, care, costs, and considerations necessary in having an outpatient infusion suite in a practice. It provides a real-life assessment of the challenges infusion centers face, including financial and clinical impacts. It is also patient centric, showing how a comfortable patient experience can improve care and increase patient compliance in an outpatient setting. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.09.012DOI Listing
February 2019
18 Reads

Clinical Trials in Rheumatology.

Rheum Dis Clin North Am 2019 Feb;45(1):79-85

Rheumatology Fellowship Program, Board of Governors, Cedars-Sinai Medical Center, David Geffen School of Medicine Center at UCLA, 8750 Wilshire Boulevard, Suite 350, Beverly Hills, CA 90211, USA. Electronic address:

Clinical trials evaluate the benefits and harms of medical interventions with the ultimate goal of establishing an evidence-based regimen that contributes to clinical decision making. Physicians benefit greatly from clinical research because it provides a greater understanding of epidemiology and health outcomes, and patients are given opportunities to participate in such trials. In this review, we discuss the challenges of conducting clinical trials investigating rheumatic diseases, including that of recruitment, finding the right trial, designing a budget, and performing a study in a timely manner. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.09.006DOI Listing
February 2019
13 Reads

Challenges to Practicing Pediatric Rheumatology.

Rheum Dis Clin North Am 2019 Feb;45(1):67-78

Pediatric Rheumatology, Hospital for Special Surgery, Hospital for Special Surgery, HSS Main Campus - Main Hospital, 535 East 70th Street 5th Floor, New York, NY 10021, USA.

Pediatric rheumatology is an exciting and rewarding career area. However, challenges when attracting trainees to this field include practice often occurring in smaller groups compared with general pediatrics, available positions requiring relocation, and fluctuation in funding resulting in uncertainty regarding training positions. Having critical mass in pediatric divisions is important to ensure adequate mentoring and people power to produce scholarly work, reduce on-call frequency and mitigate faculty absences that result in unplanned addition of clinical work. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.09.011DOI Listing
February 2019
38 Reads

The Focused Musculoskeletal Factory.

Rheum Dis Clin North Am 2019 Feb;45(1):53-66

Illinois Bone and Joint Institute, 9000 Waukegan Road, Morton Grove, IL 60053, USA. Electronic address:

Rheumatology has evolved rapidly over the past 20 years. The availability of numerous treatment interventions has dramatically altered patient outcomes and revitalized the specialty. At the same time, the economics of medical practice is challenging the practicing rheumatologist to seek more efficient and more attractive models of care delivery. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.09.005DOI Listing
February 2019
8 Reads

Challenges of Practicing Rheumatology in a Government Setting: A County Hospital and Veterans Affairs Hospital Perspective.

Rheum Dis Clin North Am 2019 Feb;45(1):39-51

Musculoskeletal Outcomes Research, University of Alabama School of Medicine, 510, 20th Street South, Faculty Office Tower, Room 805 B, Birmingham, AL 35294-000, USA.

In this article, we review the challenges and opportunities afforded by working in a government setting by providing the perspective of the Veterans Affairs experience as well as the county/public hospital experience from Los Angeles County Department of Health Services. This article highlights processes and services that are unique to practicing rheumatology in a government setting, specifically, resource allocation with clinic space and staffing; protocols for access to conventional and biologic disease modifying antirheumatic drugs; and research opportunities for rheumatologists working in a government setting. Our aim is to expand the reader's understanding of this practice setting. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0889857X183008
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http://dx.doi.org/10.1016/j.rdc.2018.09.004DOI Listing
February 2019
17 Reads

Challenges to Practicing Rheumatology in an Academic Center.

Rheum Dis Clin North Am 2019 Feb;45(1):27-37

Division of Rheumatology, Rush University Medical Center, 1611 West Harrison Street Suite 510, Chicago, IL 60612, USA. Electronic address:

Rheumatologists working in academics participate in patient care, teaching, and research. There are several challenges associated with the pursuit of these academic missions, and these are the focus of this article. Additionally, how financial pressures faced by academic institutions have led to greater emphasis on the generation of revenue from clinical activities to the detriment of other academic pursuits is discussed. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.09.003DOI Listing
February 2019
10 Reads

The Challenges of Approaching and Managing Gout.

Rheum Dis Clin North Am 2019 Feb;45(1):145-157

Division of Rheumatology, Hospital for Special Surgery, 535 East 70th Street, Suite 848G, New York, NY 10021, USA. Electronic address:

Despite many effective treatments for gout, its management remains a challenge internationally. Options for optimizing gout management may differ in different practice sizes and settings. Gout incidence is rising and it continues to be associated with increased mortality. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0889857X183008
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http://dx.doi.org/10.1016/j.rdc.2018.09.009DOI Listing
February 2019
14 Reads

Workforce Trends in Rheumatology.

Rheum Dis Clin North Am 2019 Feb;45(1):13-26

Division of Rheumatology, Department of Internal Medicine, University of Michigan, 300 North Ingalls Building, Ann Arbor, Michigan 48109, USA.

The United States is facing a rheumatology provider shortage over the next decade, which will negatively affect care for patients with rheumatic disease across the nation if this deficit is not thoughtfully addressed. The increasing numbers of retiring rheumatology specialists, women entering the workforce, and rheumatology graduates seeking part-time employment were identified as the most significant factors driving the projected decline in supply of providers. The major factors driving the projected increase in demand include an aging and growing population and improved treatment options, both of which increase disease prevalence and the challenge of managing chronic rheumatologic diseases. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.09.002DOI Listing
February 2019
1 Read

Challenges in Optimizing Medical Education for Rheumatologists.

Rheum Dis Clin North Am 2019 Feb;45(1):127-144

Division of Rheumatology, Allergy, and Immunology, Harvard Medical School, Rheumatology Fellowship Training Program, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.

The field of rheumatology has expanded rapidly in recent years, and innovations in immunology, epigenetics, and bone metabolism continue at an astonishing pace. In this fast changing field, optimizing medical education for rheumatologists is vital for maintaining a competent workforce to meet the needs of patients with rheumatic diseases. Several key challenges lie ahead and efforts to optimize medical education for rheumatologists are discussed in this article. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0889857X183008
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http://dx.doi.org/10.1016/j.rdc.2018.09.008DOI Listing
February 2019
10 Reads

Digital Medicine in Rheumatology: Challenges and Opportunities.

Rheum Dis Clin North Am 2019 Feb;45(1):113-126

Crystal Run Health, 95 Crystal Run Road, Middletown, NY 10940, USA.

The exponential growth in technology has had a significant effect on the practice of medicine and will likely transform the practice of medicine. In this article, the authors review select technologies that are already influencing the practice of rheumatology. Social media Websites such as Twitter are now important sources of information and discussion for health care professionals interested in rheumatology. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.09.010DOI Listing
February 2019
28 Reads
2.692 Impact Factor

Challenges in Implementing Treat-to-Target Strategies in Rheumatology.

Rheum Dis Clin North Am 2019 Feb;45(1):101-112

Division of Rheumatology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA; Division of Pharmacoepidemiology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.

Despite evidence that treat-to-target (TTT) approaches lead to better disease outcomes in RA, TTT is not widely implemented in rheumatology clinics in North America. This article discusses the barriers (including access to care, patient and physician factors, and systems issues) to implementing TTT in the clinic, and proposes possible solutions and future research directions. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.09.007DOI Listing
February 2019
18 Reads

The Economics of Rheumatology Practice in the United States.

Authors:
Jon Glaudemans

Rheum Dis Clin North Am 2019 Feb;45(1):1-12

United Rheumatology, 150 Motor Parkway, Suite 108E, Hauppauge, NY 11788, USA. Electronic address:

The current environment shaping rheumatology practice economics, with a focus on revenues, is described. The policies and practices of private and public insurance companies, pharmaceutical manufacturers, and pharmacy benefit managers (PBMs) are summarized, identifying economic implications for rheumatologists. The role of rebates in shaping practice economics is discussed, along with the central role of payers in defining PBM policies. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.09.001DOI Listing
February 2019
1 Read

A Three-Headed Approach to Kidney Involvement in Rheumatic Diseases.

Rheum Dis Clin North Am 2018 11;44(4):xiii-xiv

Department of Medicine, Division of Nephrology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rdc.2018.08.001DOI Listing
November 2018
7 Reads

Renal Involvement in Rheumatic Diseases.

Rheum Dis Clin North Am 2018 11;44(4):xi

Director, Division of Rheumatology, Professor of Medicine, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rdc.2018.08.002DOI Listing
November 2018
3 Reads

Renal Manifestations of Inflammatory Bowel Disease.

Rheum Dis Clin North Am 2018 11 7;44(4):699-714. Epub 2018 Sep 7.

Nephropathology, Arkana Laboratories, 10810 Executive Center Drive, Suite 100, Little Rock, AR 72211, USA.

Renal and urinary involvement has been reported to occur in 4% to 23% of inflammatory bowel disease (IBD) patients. Parenchymal renal disease is rare and most commonly affects glomerular and tubulointerstitial compartments. The most common findings on renal biopsy of IBD patients are IgA nephropathy and tubulointerstitial nephritis. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.06.007DOI Listing
November 2018
31 Reads

Autoimmune Kidney Diseases Associated with Chronic Viral Infections.

Rheum Dis Clin North Am 2018 11 7;44(4):675-698. Epub 2018 Sep 7.

Department of Medicine, Division of Nephrology, Massachusetts General Hospital, 55 Fruit Street, GRB 7, Boston, MA 02114, USA. Electronic address:

Autoimmune kidney diseases triggered by viruses are an important cause of kidney disease in patients affected by chronic viral infection. Hepatitis B virus (HBV) infection is associated with membranous nephropathy and polyarteritis nodosa. Hepatitis C virus (HCV) infection is a major cause of cryoglobulinemic glomerulonephritis. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.06.006DOI Listing
November 2018
4 Reads

Anti-Glomerular Basement Membrane Disease.

Rheum Dis Clin North Am 2018 11 7;44(4):651-673. Epub 2018 Sep 7.

Renal and Vascular Inflammation Section, Department of Medicine, Imperial College London, Commonwealth Building, Hammersmith Hospital Campus, Du Cane Road, London W12 ONN, UK; Vasculitis Clinic, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London W12 0HS, UK. Electronic address:

Anti-glomerular basement membrane (anti-GBM) disease is a rare autoimmune small vessel vasculitis characterized by autoreactivity to antigens in type IV collagen chains expressed in glomerular and alveolar basement membrane. The detection of circulating anti-GBM antibodies, which are shown to be directly pathogenic, is central to disease diagnosis. Clinically, anti-GBM disease usually presents with rapidly progressive glomerulonephritis with or without alveolar hemorrhage. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.06.011DOI Listing
November 2018
6 Reads

Thrombotic Microangiopathies with Rheumatologic Involvement.

Rheum Dis Clin North Am 2018 11 7;44(4):635-649. Epub 2018 Sep 7.

Division of Renal Diseases and Hypertension, Department of Medicine, George Washington University, 2150 Pennsylvania Avenue, Washington, DC 20037, USA. Electronic address:

Thrombotic microangiopathies are heterogeneous disorders characterized by microangiopathic hemolytic anemia with thrombocytopenia and renal injury. There are a variety of causes, including metabolic disorders, infections, medications, complement disorders, pregnancy, malignancy, and autoimmune disorders. This review focuses on renal thrombotic microangiopathy in the setting of rheumatologic diseases. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0889857X183006
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http://dx.doi.org/10.1016/j.rdc.2018.06.010DOI Listing
November 2018
40 Reads

Acute and Chronic Tubulointerstitial Nephritis of Rheumatic Causes.

Rheum Dis Clin North Am 2018 11 7;44(4):619-633. Epub 2018 Sep 7.

Department of Medicine, Division of Nephrology, Hospital Costa del Sol, A-7, Km 187, 29305 Marbella, Malaga, Spain.

Tubulointerstitial nephritis (TIN) is the second most common cause of acute intrinsic kidney injury after acute tubular necrosis. Although drug-induced forms of TIN represent the vast majority, rheumatic disease is another common cause and often underdiagnosed. Early diagnosis of acute interstitial nephritis and prompt withdrawal of the culprit medication or a correct treatment can avoid chronic damage and progressive chronic kidney disease. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.06.009DOI Listing
November 2018
30 Reads

Nephrotoxicity of Select Rheumatologic Drugs.

Rheum Dis Clin North Am 2018 11 7;44(4):605-617. Epub 2018 Sep 7.

Division of Nephrology and Hypertension, Department of Medicine, Oregon Health & Science University, Oregon Health & Science University, 3181 Southwest Sam Jackson Road, Portland, OR 97239, USA. Electronic address:

Several drugs commonly used in the management of rheumatic diseases may lead to nephrotoxicity, electrolyte disturbances, and hypertension. Here the authors focus on nonsteroidal antiinflammatory drugs, uric-acid-lowering therapy, and commonly used immunosuppressant therapies. The authors include a drug dosing table for patients with kidney disease. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.06.005DOI Listing
November 2018
9 Reads

Secondary, AA, Amyloidosis.

Rheum Dis Clin North Am 2018 11 7;44(4):585-603. Epub 2018 Sep 7.

National Amyloidosis Centre, Royal Free Campus, University College Medical School, Rowland Hill Street, London NW3 2PF, UK.

Secondary, AA, amyloidosis is a rare systemic complication that can develop in any long-term inflammatory disorder, and is characterized by the extracellular deposition of fibrils derived from serum amyloid A (SAA) protein. SAA is an acute-phase reactant synthetized largely by hepatocytes under the transcriptional regulation of proinflammatory cytokines. The kidney is the major involved organ with proteinuria as first clinical manifestation; renal biopsy is the commonest diagnostic investigation. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.06.004DOI Listing
November 2018
5 Reads

Renal Manifestations of Rheumatoid Arthritis.

Rheum Dis Clin North Am 2018 11 7;44(4):571-584. Epub 2018 Sep 7.

Department of Medicine, Division of Rheumatology, Columbia University College of Physicians and Surgeons, 630 West 168th Street, New York, NY 10032, USA.

Renal manifestations in rheumatoid arthritis (RA) have evolved as RA management has improved. In the past, older disease-modifying antirheumatic drugs, uncontrolled systemic inflammation, and chronic nonsteroidal antiinflammatory drug (NSAID) use contributed to kidney disease. Over time, the use of methotrexate and biologic medications, decrease in NSAID use, and a treat-to-target strategy have contributed to a decrease in renal manifestations. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.06.008DOI Listing
November 2018
3 Reads

Nonproliferative Forms of Lupus Nephritis: An Overview.

Authors:
Andrew S Bomback

Rheum Dis Clin North Am 2018 11 7;44(4):561-569. Epub 2018 Sep 7.

Department of Medicine, Division of Nephrology, Columbia University College of Physicians and Surgeons, 622 West 168th Street, PH 4-124, New York, NY 10032, USA. Electronic address:

Most of the attention paid to lupus nephritis, in the medical literature and in clinical trials, has primarily focused on proliferative forms of lupus nephritis (class III and IV lesions), but with lower thresholds to biopsy and rebiopsy patients with lupus, clinicians are encountering more cases with purely mesangial disease (class I and II) or membranous nephropathy patterns (class V). These lesions often will be associated with milder disease courses but still require dedicated follow-up by a nephrologist and focused therapeutic strategies that, at times, will include immunosuppression. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.06.003DOI Listing
November 2018
2 Reads

Therapy for Proliferative Lupus Nephritis.

Rheum Dis Clin North Am 2018 11 7;44(4):545-560. Epub 2018 Sep 7.

Division of Nephrology, Icahn School of Medicine at Mount Sinai, Box 1243, One Gustave L. Levy Place, New York, NY 10029, USA. Electronic address:

Proliferative lupus nephritis requires prompt diagnosis and treatment with immunosuppressive therapy. Cyclophosphamide is the longest studied agent, but mycophenolate mofetil has recently emerged as an efficacious induction and maintenance treatment that does not impart the risk of infertility. However, overall remission rates remain suboptimal and there is a need for improved therapeutic options. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.06.002DOI Listing
November 2018
2 Reads

Renal Involvement in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Rheum Dis Clin North Am 2018 11 7;44(4):525-543. Epub 2018 Sep 7.

Division of Nephrology, Vasculitis and Glomerulonephritis Center, Massachusetts General Hospital, 101 Merrimac Street, Boston, MA 02114, USA. Electronic address:

Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is the most common cause of rapidly progressive glomerulonephritis. ANCAs play an important role in the pathogenesis and diagnosis of AAV. The classic renal lesion in AAV is a pauci-immune necrotizing and crescentic glomerulonephritis. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.06.001DOI Listing
November 2018
15 Reads

Rheumatic Diseases in Older Adults.

Rheum Dis Clin North Am 2018 Aug;44(3):xiii-xiv

National Institute of Dental and Craniofacial Research, National Institutes of Health, Building 10, Room 2-1341, 10 Center Drive, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rdc.2018.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087544PMC
August 2018
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Rheumatic Diseases in Older Adults.

Rheum Dis Clin North Am 2018 Aug;44(3):xi-xii

Cedars Sinai Medical Center, David Geffen School of Medicine at UCLA, 1545 Calmar Court, Los Angeles, CA 90024, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rdc.2018.05.002DOI Listing
August 2018
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Nonsurgical Management of Osteoarthritis Knee Pain in the Older Adult: An Update.

Authors:
Nora Taylor

Rheum Dis Clin North Am 2018 Aug 12;44(3):513-524. Epub 2018 Jun 12.

Division of Rheumatology, Mid-Atlantic Permanente Medical Group, 6501 Loisdale Court, Springfield, VA 22150, USA. Electronic address:

Symptomatic knee osteoarthritis is a common complaint of many elderly patients in primary care offices. For those unable or unwilling to undergo knee replacement, the primary practitioners' understanding of the strengths and weaknesses of the available treatment modalities for pain relief is critical to successful in-office counseling and expectation management. Treatment requires a multimodal approach of nonpharmacologic and pharmacologic therapies to achieve a maximal clinical benefit. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.03.009DOI Listing
August 2018
14 Reads

Lumbar Spinal Stenosis in Older Adults.

Rheum Dis Clin North Am 2018 Aug 12;44(3):501-512. Epub 2018 Jun 12.

Department of Medicine, Loma Linda University, Loma Linda University Medical Center, 11234 Anderson Street, MC 1519, Loma Linda, CA 92354, USA. Electronic address:

Lumbar spinal stenosis (LSS) is a frequent cause of low back pain among adults, caused by a narrowing impinging on the spinal cord or nerve roots. Several conditions cause LSS, including disc herniation, spondylolisthesis, tumor, fractures, and other degenerative changes. Back pain is frequently experienced. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.03.008DOI Listing
August 2018
26 Reads

Crystal-Induced Arthritides in the Elderly: An Update.

Rheum Dis Clin North Am 2018 Aug 12;44(3):489-499. Epub 2018 Jun 12.

Department of Rheumatic and Immunologic Disease, Cleveland Clinic Lerner College of Medicine, 9500 Euclid Avenue, A50, Cleveland, OH 44195, USA.

The prevalence of gout increases with age. After the serum concentration of urate exceeds the saturation or solubility point, it deposits in and around the joints. Presentation in the elderly is often atypical and challenging to diagnose. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.03.007DOI Listing
August 2018
2 Reads

Update on Cardiovascular Disease Risk in Patients with Rheumatic Diseases.

Rheum Dis Clin North Am 2018 Aug 12;44(3):475-487. Epub 2018 Jun 12.

Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, 3500 Terrace Street, Thomas E. Starzl Biomedical Science Tower South 711, Pittsburgh, PA 15261, USA.

Cardiovascular disease (CVD) risk is 1.5-fold higher in rheumatoid arthritis (RA), partly due to subclinical atherosclerosis that develops before the diagnosis of RA. Dyslipidemia in RA is better quantified by lipoproteins and apolipoproteins than by cholesterol levels. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.03.006DOI Listing
August 2018
5 Reads

Regional Rheumatic Disorders and Rehabilitation in Older Adults: An Update.

Rheum Dis Clin North Am 2018 Aug;44(3):453-473

Rehabilitation Medicine Department, National Institutes of Health Clinical Center, 10 Center Drive, Building 10, CRC, Room 1-1469, Bethesda, MD 20892-1604, USA.

Musculoskeletal problems are the most frequently reported complaints among older adults living in the community. The impact of the aging process on skeletal muscles and joints can have a profound effect on the ability of individuals to function. This article reviews the rehabilitation medicine approach to the evaluation of older adults with regional rheumatic disorders and the rehabilitation medicine considerations for clinical intervention. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.03.005DOI Listing
August 2018
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A Review of Osteoporosis in the Older Adult: An Update.

Rheum Dis Clin North Am 2018 Aug 13;44(3):437-451. Epub 2018 Jun 13.

Division of Rheumatology, MedStar Washington Hospital Center, Georgetown University Medical Center, 110 Irving Street Northwest 2A-66, Washington, DC 20010, USA.

Osteoporosis in the elderly population is common. It results in more than 1.5 million fractures per year in the United States. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.03.004DOI Listing
August 2018
22 Reads

Update on Sjögren Syndrome and Other Causes of Sicca in Older Adults.

Rheum Dis Clin North Am 2018 08;44(3):419-436

National Institute of Dental and Craniofacial Research, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA.

Dry eye and dry mouth symptoms are each reported by up to 30% of persons more than 65 years of age, particularly in women. Medication side effects are the most common contributing factors. The evaluation of these symptoms requires measures of ocular and oral dryness. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245643PMC
August 2018
6 Reads

The Relationship Between Rheumatologic Disorders and Malignancies.

Authors:
Mandana Hashefi

Rheum Dis Clin North Am 2018 08 13;44(3):405-418. Epub 2018 Jun 13.

Division of Rheumatology, George Washington University, 2300, M Street, Northwest, Suite: 3-307, Washington, DC 20037, USA. Electronic address:

A variety of conditions mimicking rheumatologic syndromes may be associated with an underlying malignancy. Therefore, distinguishing these syndromes from more common, nonparaneoplastic rheumatologic conditions can be perplexing. Some autoimmune conditions and the medications used for their management can be associated with increased future risk of malignancy. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.03.003DOI Listing
August 2018
11 Reads