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Rev Neurol 2019 Apr;68(8):356

Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, Espana.

Rev Neurol 2019 Apr;68(8):354-355

Hospital Clinico Universitario Lozano Blesa, 50009 Zaragoza, Espana.

Rev Neurol 2019 Apr;68(8):346-353

CHUVI. Complexo Hospitalario Alvaro Cunqueiro, Vigo, Espana.

Introduction: Hubris syndrome (HS) is an acquired psychiatric disorder that affects people who exercise power in any of its forms. It has been reported in many fields, from politics to finance. The physician-patient relationship is also one of power. Read More

Rev Neurol 2019 Apr;68(8):339-345

Pontificia Universidad Javeriana, Bogota DC, Colombia.

Introduction: Postictal neurogenic pulmonary oedema is an infrequent condition of varying severity, probably related to sudden unexpected death in epilepsy (SUDEP). It is more frequent in patients with generalised tonic-clonic seizures of long duration or with status epilepticus.

Aim: Based on a review of the literature, the aim is to describe the clinical characteristics, pathophysiology, radiological findings, treatment and prognosis of patients with postictal pulmonary oedema. Read More

Rev Neurol 2019 Apr;68(8):333-338

Hospital Regional Universitario de Malaga, Malaga, Espana.

Introduction: The inmuno checkpoints inhibitors are new revolutionary treatment for many neoplastic diseases in advanced stadium. There are described several types of neurological complications induced by nivolumab: polyneuropathy, seizures, radiculitis and myasthenia gravis disease.

Case Report: A 65 years old man with metastatic lung adenocarcinoma who presented myasthenia gravis disease induced by avelumab therapy with good response to treatment with pyridostigmine and withdrawal of avelumab. Read More

Rev Neurol 2019 Apr;68(8):326-332

Universidad de Valencia, Burjasot, Espana.

Introduction: Vertigo and dizziness are symptoms with a significant burden in the hospital and involve several specialties. There are few guidelines of radiological tests for these symptoms.

Aims: To know which profile of patients with vertigo and dizziness has neuroimaging tests, quantify and describe the radiological findings. Read More

Rev Neurol 2019 Apr;68(8):321-325

Instituto de Neurologia y Neurocirugia de Mexico, Mexico DF, Mexico.

Introduction: Acute seizures in patients with epilepsy are a potential of source of neurological damage; their causes must be researched.

Aim: To explore the epidemiology of acute seizure exacerbations in patients with epilepsy in a neurological emergency department in Mexico City.

Patients And Methods: Descriptive prospective study of patients with a previous diagnosis of epilepsy that receive medical care in an emergency department due to acute seizures. Read More

Rev Neurol 2019 Apr;68(8):315-320

Universitat de Barcelona, 08035 Barcelona, Espana.

Introduction: This research falls within the category of longitudinal studies assessing the evolution of prematurely born infants with the use of standardized tests.

Aims: To analyze the trajectory of the mental development of a group of premature infants and to identify if gestational age is a significant predictor of their evolution.

Subjects And Methods: 359 prematurely born infants were assessed at three stages of their development (between 1-9 months, 10-18 months and 19-30 months of age), using the Bayley Scales of Infant DEVELOPMENT. Read More

Rev Neurol 2019 Apr;68(7):312-314

Hospital Infantil Universitario Nino Jesus, 28009 Madrid, Espana.

Rev Neurol 2019 Apr;68(7):301-311

Hospital Universitari i Politecnic La Fe, Valencia, Espana.

Introduction: Checkpoint inhibitors have dramatically transformed cancer treatment. However, due to the increasing number of tumors in which they are used, there is a high number of reported adverse effects. Among them, we highlight neurological side effects. Read More

Rev Neurol 2019 Apr;68(7):295-300

Hospital Universitario Ramon y Cajal, 28034 Madrid, Espana.

Introduction: Isolated acute amnesia is an exceptional presenting symptom of thalamic stroke. This study analyses the clinical profile, the diagnosis, the treatment and the prognosis of these patients.

Case Reports: We conducted a retrospective review of the cases of thalamic infarct that presented exclusively as acute amnesia in our university tertiary hospital (n = 3) and a review of similar cases in PubMed (n = 20). Read More

Rev Neurol 2019 Apr;68(7):281-289

Universidad de Santiago de Compostela, Santiago de Compostela, Espana.

Introduction: There is evidence to suggest that cognitive stimulation produces cognitive benefits in people with mild neurocognitive disorder. However, the effect has been previously demonstrated to be minimal to moderate and the effect of long-term individual interventions, namely on specific cognitive domains, is unknown.

Aim: To assess the efficacy, feasibility and acceptability of a long-term individual cognitive stimulation intervention for patients with mild neurocognitive disorder. Read More

Rev Neurol 2019 Apr;68(7):271-280

Instituto Nacional de Psiquiatria Ramon de la Fuente Muniz, 14370 Mexico DF, Mexico.

Introduction: Cognitive effects caused by cocaine and crack consumption, especially deficits in executive functions may increase the likelihood of drug-seeking behaviour and interfere with the ability of users to assimilate and participate in rehabilitation programs.

Aim: To determine in early abstinence the state of executive functions, the impulsiveness and craving in cocaine and crack consumers.

Subjects And Methods: This cross-sectional study functions, with a sample of 60 male aged between 31. Read More

Rev Neurol 2019 Mar;68(6):270

Universidad Complutense de Madrid, Madrid, Espana.

Rev Neurol 2019 Mar;68(6):269-270

Hospital Universitario Central de Asturias, Oviedo, Espana.

Rev Neurol 2019 Mar;68(6):268-269

Hospital Baca Ortiz, Quito, Ecuador.

Rev Neurol 2019 Mar;68(6):267-268

Hospital de Sagunto, 46520 Sagunto, Espana.

Rev Neurol 2019 Mar;68(6):266-267

Complejo Hospitalario de Navarra, Pamplona, Espana.

Rev Neurol 2019 Mar;68(6):264-265

Hospital Universitario Central de Asturias, 33006 Oviedo, Espana.

Rev Neurol 2019 Mar;68(6):255-263

Hospital La Fe, 46009 Valencia, Espana.

Introduction: Epileptic seizures and epilepsy are part of daily clinical practice in neurology. Yet, the number of false positive diagnoses is surprisingly high. Almost one out of every five patients treated for epilepsy does not really have this diagnosis, which is a high percentage bearing in mind the social and medical consequences that being diagnosed with epilepsy entails. Read More

Rev Neurol 2019 Mar;68(6):250-254

Pontificia Universidad Javeriana, Bogota DC, Colombia.

Introduction: Reversible cerebral vasoconstriction syndrome (RCVS) is a low incidence disability with a multifactorial etiology and a wide array of symptoms. The main symptom is a thunderclap headache, accompanied sometimes with various neurological deficits that can lead to death. RCVS is usually diagnosed through radiological imaging technology. Read More

Rev Neurol 2019 Mar;68(6):241-249

Hospital Internacional de Colombia, Bucaramanga, Colombia.

Introduction: Non-fluent aphasia is a frequent complication in post-ischemic stroke patients, with repetitive transcranial magnetic stimulation (rTMS) being one of the possible treatment alternatives.

Aim: To assess the efficacy and safety of rTMS in patients with non-fluent after-ischemic stroke aphasia.

Patients And Methods: Double blind, randomized controlled clinical trial in post-stroke patients who were assigned to receive 10 sessions (one daily) of active treatment or placebo of rTMS, without the addition of language therapy. Read More

Rev Neurol 2019 Mar;68(6):236-240

HUMS. Hospital Universitario Miguel Servet, 50009 Zaragoza, Espana.

Introduction: The great vulnerability of the striatocapsular region to ischaemia means that mechanical thrombectomy has its limitations in occlusions of large-calibre vessels when it comes to preventing the striatocapsular region from undergoing infarction.

Aims: To analyse the effect of endovascular treatment on the incidence of isolated striatocapsular infarction (iSCI) and to describe its clinical characteristics.

Patients And Methods: We conducted a retrospective study to analyse the incidence of iSCI following treatment of cerebral reperfusion. Read More

Rev Neurol 2019 Mar;68(6):229-235

Hospital de Sao Joao, 4200-351 Porto, Portugal.

Introduction: There is poor knowledge on current hospitalizations in the multiple sclerosis (MS) population. The purpose of this study was to determine hospitalization causes and outcomes in a MS hospital-based cohort.

Patients And Methods: A retrospective chart review was performed on all patients admitted at our centre between August, 2009 and July, 2015, excluding those with no previous established diagnosis. Read More

Rev Neurol 2019 Mar;68(5):213-228

Rev Neurol 2019 Mar;68(5):207-212

Universidad de Valencia, 46071 Valencia, Espana.

There was a time when clinicians looked down on any decision-making that did not depend on their own judgement. Statisticians laughed at such naivety, as they were fully aware of the extent to which the heuristics that guide human decisions are capable of error, even in the most highly trained individuals. More than 60 years after the beginning of this conflict, the two standpoints have still not been adopted in clinical psychology or in neuropsychology. Read More

Rev Neurol 2019 Mar;68(5):199-206

University of California, San Francisco, EE.UU.

The fragile X associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disease associated with the repetition of CGG triplets (55-200 CGG repetitions) in the FMR1 gene. The premutation of the FMR1 gene, contrasting with the full mutation (more than 200 CGG repetitions), presents an increased production of messenger and a similar or slightly decreased production of FMRP protein. FXTAS affects 40% of men and 16% of women carriers of the premutation. Read More

Rev Neurol 2019 Mar;68(5):190-198

CRE de atencion a personas con enfermedad de Alzheimer y otras demencias - Imserso, Salamanca, Espana.

Introduction: There is a growing need for scientific studies and tools that allow the evaluation of the effects at an affective level of some non-pharmacological therapies for people with dementia such as the creative therapeutic dance.

Aims: To explore the validity and reliability of the Profile of Mood States (POMS) in people with dementia and to analyse the possible differences in the scores of the participants before and after sessions of creative therapeutic dance.

Patients And Methods: POMS was administered to 36 people with dementia before and after four group sessions of creative therapeutic dance. Read More

Rev Neurol 2019 Mar;68(5):181-189

Universidad Rey Juan Carlos, 28922 Alcorcon, Espana.

Introduction: Vertical immersion induces a variety of physiological responses in different body systems, depending on the properties of fluid mechanics, which are the basis that underpins aquatic therapy programs in different pathologies.

Aim: To perform a systematic review to analyze and describe the effects that vertical immersion produces on the nervous system in healthy subjects.

Subjects And Methods: A systematic search of the existing literature was conducted in the databases BRAIN, PubMed, PEDro and Web of Science. Read More

Rev Neurol 2018 Nov;67(s01):S1-S21

Hospital La Fe, 46009 Valencia, Espana.

«Apuntes en Neurologia» is an initiative in which prominent national and international leaders, with broad academic recognition, came together to synthesise the most outstanding clinical aspects within their area of interest and to discuss the latest developments in a more accessible language. Understanding the factors that affect the onset and progression of any neurological disease through a review is important to be able to develop strategies to reduce the burden of these diseases. Moreover, knowledge of the clinical aspects is essential to solve the problems of daily clinical practice. Read More

Rev Neurol 2019 Feb;68(4):179-180

Centro Hospitalar de Vila Nova de Gaia, Vila Nova de Gaia, Portugal.

Rev Neurol 2019 Feb;68(4):171-178

Rev Neurol 2019 Feb;68(4):169-170

Hospital Universitario Donostia, San Sebastian, Espana.

Rev Neurol 2019 Feb;68(4):160-168

Hospital Universitari de Bellvitge, Hospitalet de Ll., Espana.

Cognitive toxicity induced by cranial radiation is one of the most important limitations of radiation therapy and has a significant impact on brain tumor survivors' quality of life. This review comprehends an up to date of recent studies including complete neuropsychological battery and/or advanced neuroimaging techniques. These studies identified critical anatomical and/or functional brain areas related to radiation-induced brain injury, thus improving clinical and radiological diagnosis. Read More

Rev Neurol 2019 Feb;68(4):155-159

Hospital de Ninos de la Santisima Trinidad, Cordoba, Argentina.

Introduction: CLN8 disease is one of the thirteen recognized genetic types of neuronal ceroid lipofuscinosis, a group of neurodegenerative lysosomal storage disorders, most frequent in childhood. A putative 286 amino acids transmembrane CLN8 protein with unknown function is affected. Pathological variants in the CLN8 gene were associated with two different phenotypes: variant late-infantile in individuals from many countries worldwide, and epilepsy progressive with mental retardation, appearing in Finnish and Turkish subjects. Read More

Rev Neurol 2019 Feb;68(4):147-154

Departamento de Salud del Gobierno Vasco, Bilbao, Espana.

Introduction: The relationship between socioeconomic status and incidence or stroke mortality rates is well established. The evidence of an association between this variable and survival is less conclusive. Level of education is a widely-used measure of socioeconomic status in elderly people. Read More

Rev Neurol 2019 Feb;68(4):137-146

Division de Ciencias de la Salud. Universidad de Quintana Roo, Chetumal, Quintana Roo, Mexico.

Introduction: Hazardous alcohol consumption (HAC) is a pattern of alcohol use that may result in harm for the user and/or for those around them. Prior research has suggested that HAC and alcohol dependence share some neurophysiological features but differ in others.

Aim: To determine whether HAC and alcohol dependence presented different neurophysiological correlates. Read More

Rev Neurol 2019 Feb;68(4):135-136

Hospital Rey Juan Carlos, Mostoles, Espana.

Rev Neurol 2019 Feb;68(3):134

CARIBRO/ I.C.B.P , Habana, Cuba.

Rev Neurol 2019 Feb;68(3):132-133

Hospitals Vall d'Hebron, 08035 Barcelona, Espana.

Rev Neurol 2019 Feb;68(3):131-132

Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

Rev Neurol 2019 Feb;68(3):125-130

Rev Neurol 2019 Feb;68(3):123-124

Hospital San Juan de la Cruz, 23400 Ubeda, Espana.

Rev Neurol 2019 Feb;68(3):118-122

Universidad Miguel Hernandez, Elche, Espana.

Aim: To develop a proposal for a portfolio of services and a set of indicators for Headache Units.

Development: Qualitative study that applied techniques of consensus with the participation of 15 professionals who are experts in the treatment of headaches (experience of 15 years) and in quality assurance. The description of the indicators included: statement, definition, standard, type of indicator, dimension, source, level of evidence, and clarification of terms. Read More

Rev Neurol 2019 Feb;68(3):111-117

Hospital San Pedro, Logrono, Espana.

Introduction: The microbiota is the set of millions of microorganisms that coexist in a symbiotic way in our body. It is mainly located in the digestive tract, being distributed in function of the chemical properties and the functions of the different organs. The factors that influence its composition are multiple (diet, individual habits, diseases or drugs). Read More

Rev Neurol 2019 Feb;68(3):107-110

Hospital General Universitario Gregorio Maranon, Madrid, Espana.

Introduction: The pathophysiology of restless legs syndrome (RLS) is complex. Secondary RLS with iron deficiency -which suggests disturbed iron homeostasis- remains to be elucidated.

Case Reports: We report the findings from a unique blood donor family with RLS. Read More

Rev Neurol 2019 Feb;68(3):99-106

Facultad de Psicologia. Universidad Autonoma de Barcelona., Bellaterra (Cerdanyola del Valles), Espanya.

Introduction: The 22q11 deletion syndrome (S22q11) is a genetic disorder caused by the loss of a fragment of the chromosome 22. The clinical manifestations associated with the syndrome are diverse, including learning difficulties and alterations in voice, speech and language. However, to date we have not found any study that evaluates these aspects in the Spanish population with S22q11. Read More

Rev Neurol 2019 Feb;68(3):91-98

Hospital General de Mexico OD, Cuauhtemoc, Mexico.

Introduction: Since, under certain circumstances, defensive or attacking behaviours display a pattern of motor dominance, as observed in subjects who participate in contact or fighting sports, aggressive behaviour was considered to have a dominant motor pattern. With the aim of preventing the functional problems reported with bilateral lesion procedures involving both the central nucleus of the amygdala and the posteromedial hypothalamus, the decision was made to combine them; thus, an amygdalotomy of the central nucleus of the amygdala and a posteromedial hypothalamotomy were to be performed simultaneously and unilaterally, on the basis of the motor dominance of the patient determined by means of the Edinburgh test.

Patients And Methods: This study describes the surgical experience in a series of nine patients diagnosed with refractory neuroaggressive syndrome. Read More

Rev Neurol 2019 Jan;68(2):89-90

Complejo Hospitalario Universitario de Vigo, Vigo, Espana.