2,805 results match your criteria Revista da Associacao Medica Brasileira 1992[Journal]


Central role of obesity in endothelial cell dysfunction and cardiovascular risk.

Rev Assoc Med Bras (1992) 2019 Jan;65(1):87-97

. Laboratory of Vascular Biology and Atherosclerosis, Department of Internal Medicine, State University of Campinas (Unicamp), Campinas, SP, Brasil.

Atherosclerosis is the leading cause of mortality in the contemporary world. The critical role of the endothelial cells (EC) in vascular homeostasis, the metabolic changes that take place when the cell is activated, and the elements involved in these processes have been widely explored over the past years. Obesity and its impact, promoting a rise in blood levels of free fatty acids (FAs) are often associated with atherosclerosis and cardiovascular mortality. Read More

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http://dx.doi.org/10.1590/1806-9282.65.1.87DOI Listing
January 2019

Inhibition of the sodium-glucose co-transporter 2 in the elderly: clinical and mechanistic insights into safety and efficacy.

Rev Assoc Med Bras (1992) 2019 Jan;65(1):70-86

Laboratory of Atherosclerosis and Vascular Biology, Unicamp, Campinas, SP, Brasil.

The prevalence of type 2 diabetes mellitus (T2DM) in the elderly grew sharply over the last decade. Reduced insulin sensitivity and secretory capacity, weight gain, sarcopenia, and elevated adiposity are all common metabolic and body changes in the aging population that favor an increased risk of hypoglycemia, frailty syndrome, falls, and cognitive dysfunction. First line antidiabetic therapy is frequently not safe in older individuals because of its high risk of hypoglycemia and prevalent co-morbid diseases, such as chronic kidney disease, osteoporosis, cardiovascular disease, and obesity. Read More

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http://dx.doi.org/10.1590/1806-9282.65.1.70DOI Listing
January 2019

Diabetic cardiomyopathy: factual or factoid?

Rev Assoc Med Bras (1992) 2019 Jan;65(1):61-69

Subject of Cardiology, Faculty of Medical Sciences - State University of Campinas (Unicamp), Campinas, SP, Brasil.

Although long ago described, there is no established consensus regarding the real existence of Diabetic Cardiomyopathy (CMPDM). Due to its complex pathophysiology, it has been difficult for clinical and experimental research to establish clear connections between diabetes mellitus (DM) and heart failure (HF), as well as to solve the mechanisms of the underlying myocardial disease. However, the epidemiological evidence of the relationship of these conditions is undisputed. Read More

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http://dx.doi.org/10.1590/1806-9282.65.1.69DOI Listing
January 2019

Cardiovascular autonomic neuropathy in type 2 diabetic patients.

Rev Assoc Med Bras (1992) 2019 Jan;65(1):56-60

Full Professor - Department of Cardiology - Laboratory of Vascular Biology and Atherosclerosis - FCM - Unicamp - São Paulo (SP) - Brasil.

Diabetes is one of the most common chronic pathologies around the world, involving treatment with general clinicians, endocrinologists, cardiologists, ophthalmologists, nephrologists and a multidisciplinary team. Patients with type 2 Diabetes Mellitus (T2DM) can be affected by cardiac autonomic neuropathy, leading to increased mortality and morbidity. In this review, we will present current concepts, clinical features, diagnosis, prognosis, and possible treatment. Read More

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http://dx.doi.org/10.1590/1806-9282.65.1.56DOI Listing
January 2019
2 Reads

Diabetic regulation of subjects with type 2 diabetes mellitus is associated with serum vitamin D levels.

Rev Assoc Med Bras (1992) 2019 Jan;65(1):51-55

Abant Izzet Baysal University Hospital, Faculty of Medicine, Department of Internal Medicine, Bolu, Turkey.

Objective: Vitamin D deficiency is not only associated with bone metabolism but also with diabetes mellitus. We aimed to study the possible association between serum vitamin D concentration and HbA1c level in patients with type 2 diabetes mellitus (T2DM) in this retrospective report.

Methods: Patients with T2DM were enrolled to the study either in regulated or non-regulated T2DM groups, according to HbA1c levels. Read More

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http://dx.doi.org/10.1590/1806-9282.65.1.51DOI Listing
January 2019

Consumption of animal-based and processed food associated with cardiovascular risk factors and subclinical atherosclerosis biomarkers in men.

Rev Assoc Med Bras (1992) 2019 Jan;65(1):43-50

Heart Institute (InCor) of the Hospital das Clínicas of the Faculty of Medicine, USP, São Paulo(SP), Brasil.

Objective: To evaluate the frequency of food consumption in apparently healthy men and their association with cardiovascular risk factors and biomarkers of subclinical atherosclerosis.

Methods: In this observational study, 88 men had their food standard obtained through the food frequency questionnaire (FFQ). Associations of dietary patterns with cardiovascular risk factors, such as anthropometric data, laboratory and clinical evaluations, carotid-femoral arterial stiffness (IMT) and pulse wave velocity were evaluated. Read More

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http://dx.doi.org/10.1590/1806-9282.65.1.43DOI Listing
January 2019

Diabetes control could through platelet-to-lymphocyte ratio in hemograms.

Rev Assoc Med Bras (1992) 2019 Jan;65(1):38-42

Abant Izzet Baysal University Hospital, Department of Internal Medicine, Bolu, Turkey.

Objective: Association between type 2 diabetes mellitus and inflammation is well-established. We aimed to study platelet-to-lymphocyte ratio (PLR), a novel inflammatory index derived from hemogram, in diabetic patients in comparison to those in healthy volunteers.

Methods: Medical data of type 2 diabetics that showed up in general outpatient medical clinics of our institution between February 2017 and August 2017 were recorded and analyzed. Read More

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http://dx.doi.org/10.1590/1806-9282.65.1.38DOI Listing
January 2019

The efficacy of saxagliptin in T2DM patients with non-alcoholic fatty liver disease: preliminary data.

Rev Assoc Med Bras (1992) 2019 Jan;65(1):33-37

Department of Ultrasonography, Qilu Hospital of Shandong University (Qingdao), Shandong Province, China.

Objective: To investigate the clinical efficacy and the possible mechanisms of saxagliptin in the treatment of type 2 diabetes mellitus (T2DM) combined with non-alcoholic fatty liver disease (NAFLD).

Methods: A total of 95 T2DM and NAFLD patients were randomly divided into group A (saxagliptin group), group B (glimepiride group), and group C (glimepiride combined with polyene phosphatidylcholine group).

Results: After intervention treatment for 24 w, body mass index (BMI), waist-to-hip ratio (WHR), glycated haemoglobin (HbA1c), fasting plasma glucose (FPG), fasting insulin (FINS), homeostatic model assessment of insulin resistance (HOMA-IR), interleukin-6 (IL-6), triglyceride (TG), total cholesterol (TC), alanine aminotransferase (ALT), aspartate aminotransferase (AST), γ-glutamyltransferase (γ-GT), and quantitative detection of liver steatosis of study subjects were observed, the action of liver steatosis in subjects of groups A and C were significantly different from those of group B; however, there were no differences between groups A and C. Read More

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http://dx.doi.org/10.1590/1806-9282.65.1.33DOI Listing
January 2019
1 Read

Intensive treatment of hyperglycemia in the acute phase of myocardial infarction: the tenuous balance between effectiveness and safety - a systematic review and meta-analysis of randomized clinical trials.

Rev Assoc Med Bras (1992) 2019 Jan;65(1):24-32

Cardiology Department, Faculty of Medical Sciences, State University of Campinas (Unicamp), Campinas, SP, Brasil.

Introduction: In acute myocardial infarction (AMI), each 18 mg/dl (1 mmol/L) increment is associated with a 3% increase in mortality rates. All strategies applied for reducing blood glucose to this date, however, have not presented encouraging results.

Methodology: We searched the Medline (PubMed) and Cochrane Library databases for randomized clinical trials (RCTs) from 1995 to 2017 that used the intensive strategy or GIK therapy for blood glucose control during the acute stage of the AMI. Read More

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http://dx.doi.org/10.1590/1806-9282.65.1.24DOI Listing
January 2019

Clinical registry of cardiovascular surgeries in a university hospital.

Rev Assoc Med Bras (1992) 2019 Jan;65(1):16-23

Post-Graduate Program Research and Innovation Processes in Health, Cardiology Institute of the University Foundation of Cardiology - Porto Alegre - RS , Brasil.

Objectives: To create and implement a computerized clinical registry to verify in the short-, medium- and long-term the mortality and the incidence of significant surgical outcomes in adult patients submitted to cardiovascular surgeries.

Methods: This is a prospective, observational registry-based study aimed at documenting the characteristics of patients undergoing cardiovascular surgery.

Results: Variables were standardized according to international references from the Society of Thoracic Surgeons (STS), American College of Cardiology (ACC), Michigan Society of Thoracic and Cardiovascular Surgeons (MSTCVS) and the Department of Informatics of SUS (DATASUS). Read More

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http://dx.doi.org/10.1590/1806-9282.65.1.16DOI Listing
January 2019

Serum uric acid to HDL-cholesterol ratio is a strong predictor of metabolic syndrome in type 2 diabetes mellitus.

Rev Assoc Med Bras (1992) 2019 Jan;65(1):9-15

Abant Izzet Baysal University, Faculty of Medicine, Department of Internal Medicine, Bolu, Turkey.

Objective: Metabolic syndrome (MS) is a clinical entity that associated with increased risk of type 2 Diabetes Mellitus (DM) and cardiovascular diseases. Serum uric acid levels are correlated MS criteria. We hypothesized whether a uric acid to HDL-cholesterol ratio (UHR) could predict diabetic regulation and presence of MS in type 2 diabetic subjects. Read More

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http://dx.doi.org/10.1590/1806-9282.65.1.9DOI Listing
January 2019

Prevalence, treatment, and control of dyslipidemia in diabetic participants of two brazilian cohorts: a place far from heaven.

Rev Assoc Med Bras (1992) 2019 Jan;65(1):3-8

Cardiology Department, Faculty of Medical Sciences, State University of Campinas (Unicamp), Campinas, SP, Brasil.

Objective: Diabetes is one of the leading causes of cardiovascular mortality. Over the last years, mortality has decreased significantly, more in individuals with diabetes than in healthy ones. That is mostly due to the control of other cardiovascular risk factors. Read More

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http://dx.doi.org/10.1590/1806-9282.65.1.3DOI Listing
January 2019

Diabetes and premature death.

Rev Assoc Med Bras (1992) 2019 01;65(1):1-2

Editor in chief - Journal of the Brazilian Medical Association, São Paulo, SP, Brasil.

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http://dx.doi.org/10.1590/1806-9282.65.1.1DOI Listing
January 2019

Association of Interleukin-10 -1082A>G (rs1800896) Polymorphism with Predisposition to Breast Cancer: a Meta-Analysis based on 17 Case-Control Studies.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):756-764

. Department of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Yazd, Iran.

Introduction: The association between the between IL-10 -1082A>G (rs1800896) polymorphism and breast cancer has been evaluated by several number case-control studies. However, these studies might be underpowered to reveal the true association.

Objective: We have performed a comprehensive meta-analysis to investigate the association IL-10 -1082A>G polymorphism and breast cancer. Read More

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http://dx.doi.org/10.1590/1806-9282.64.08.756DOI Listing
August 2018
3 Reads
0.915 Impact Factor

Anthracycline-associated cardiotoxicity in adults: systematic review on the cardioprotective role of beta-blockers.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):745-754

. School of Sciences of Santa Casa de Misericórdia de Vitoria, Vitória, ES, Brasil.

Objectives: This study aimed at assessing the role of beta-blockers on preventing anthracycline-induced cardiotoxicity in adults.

Methods: A systematic review was performed on electronic databases, including relevant studies that analysed beta-blockers as cardioprotective agents before the use of anthracyclines by adult oncologic patients.

Results: After application of eligibility and selection criteria, eight articles were considered as high quality, complying with the proposed theme; all eight clinical trials, four of them placebo-controlled, with a total number of 655 patients included. Read More

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http://dx.doi.org/10.1590/1806-9282.64.08.745DOI Listing
August 2018
4 Reads

Characterization of post-surgical critical patients with infections associated with healthcare after prolonged perfusion of remifentanil.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):736-742

. Departamento de Farmacología e Instituto de Neurociencias. Facultad de Medicina, Universidad de Granada, Granada, Spain.

Introduction: Healthcare associated infections (HAI) are the most frequent complication of hospitalized patients. The aim of this study was to describe the clinical and epidemiological characteristics of critically ill post-surgical patients with a diagnosis of healthcare associated infections, after a pattern of sedoanalgesia of at least 4 days.

Methods: All patients over 18 years of age with a unit admission of more than 4 days were consecutively selected. Read More

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http://dx.doi.org/10.1590/1806-9282.64.08.736DOI Listing
August 2018
2 Reads

Clinical, ultrasonographic and histological findings in varicose vein surgery.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):729-735

. Medical Science Faculty of the Santa Casa of São Paulo, São Paulo/SP, Brasil.

Objective: This study aims to correlate the demographic data, different clinical degrees of chronic venous insufficiency (CEAP), ultrasound findings of saphenofemoral junction (SFJ) reflux, and anatomopathological findings of the proximal segment of the great saphenous vein (GSV) extracted from patients with primary chronic venous insufficiency (CVI) submitted to stripping of the great saphenous vein for the treatment of lower limb varicose.

Method: This is a prospective study of 84 patients (110 limbs) who were submitted to the stripping of the great saphenous vein for the treatment of varicose veins of the lower limbs, who were evaluated for CEAP clinical classification, the presence of reflux at the SFJ with Doppler ultrasonography, and histopathological changes. We study the relationship between the histopathological findings of the proximal GSV withdrawal of patients with CVI with a normal GSV control group from cadavers. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/1806-9282.64.08.729DOI Listing
August 2018
5 Reads

Diagnosis and management of systemic hypertension due to renovascular and aortic stenosis in patients with Williams-Beuren syndrome.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):723-728

. Pediatric Nephrology Unit, Institute of Children, Hospital das Clínicas, Faculty of Medicine, University of São Paulo, São Paulo, Brasil.

Aim: To describe the incidence, diagnosis, and management of systemic arterial hypertension related to renal artery stenosis in patients with Williams-Beuren syndrome.

Methods: Sixty-five patients with Williams-Beuren syndrome were evaluated for hypertension. Enrolled patients underwent Doppler sonography of the renal arteries and Doppler echocardiography. Read More

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http://dx.doi.org/10.1590/1806-9282.64.08.723DOI Listing
August 2018
2 Reads

Analysis of survival in patients with brain metastases treated surgically: Impact of age, gender, oncologic status, chemotherapy, radiotherapy, number and localization of lesions, and primary cancer site.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):717-722

. Neurosurgery Service of the Public Servant's Hospital of the State of São Paulo (HSPE-SP), São Paulo/SP, Brasil.

Objective: To evaluate the survival of patients with brain metastases treated surgically according to the potentially involved factors.

Methods: 71 patients treated surgically were analyzed with the diagnosis of brain metastases during the period from January 2011 to November 2014, totaling 47 months of follow-up. The Kaplan-Meier curve method was used for survival analysis. Read More

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http://dx.doi.org/10.1590/1806-9282.64.08.717DOI Listing
August 2018
1 Read

Assessment of quality of life in patients with advanced oral cancer who underwent mandibulectomy with or without bone reconstruction.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):710-716

. Discipline of Head and Neck Surgery, Faculty of Medicine, University of São Paulo, São Paulo/SP, Brasil.

Introduction: Malignant neoplasms of the head and neck, due to its anatomical location, can cause significant alterations in vital functions related to feeding, communication and social interaction of the affected patients.

Objective: To analyze the quality of life of patients with advanced malignant neoplasms of the oral cavity and submitted to radical operations with curative intent.

Material And Methods: 47 patients with oral cavity squamous cell carcinoma (SCC), in stages III and IV, underwent surgical treatment with segmental mandibulectomy and complementary radiotherapy. Read More

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http://dx.doi.org/10.1590/1806-9282.64.08.710DOI Listing
August 2018
1 Read

Clinical features of patients with chronic non-specific neck pain per disability level: A novel observational study.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):700-709

Department of Physical Therapy, Superior Center for University Studies La Salle, Autonomous University, Autónoma University of Madrid, Spain.

Background: To date, there are no cross-sectional studies considering the influence of disability level in patients with non-specific chronic neck pain. Therefore, the main aim of this study was to determine kinesiophobia, active cervical range of movement (CROM), and pressure pain threshold (PPT) differences between different disability levels (mild, moderate, and severe) in subjects with non-specific chronic neck pain and asymptomatic subjects.

Methods: A descriptive cross-sectional study. Read More

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http://dx.doi.org/10.1590/1806-9282.64.08.700DOI Listing
August 2018
1 Read

Is doctor-patient relationship influenced by health online information?

Rev Assoc Med Bras (1992) 2018 Aug;64(8):692-699

. Health College of Pernambuco, Pernambuco, Brasil.

Objectives: To analyse the opinions and attitudes reported by medical specialists regarding online health information and their interference in the doctor-patient relationship.

Methods: A cross-sectional study developed between 2016 and 2017 in Recife-Pernambuco-Brazil, which used a questionnaire in person in a population of 183 specialists from the Instituto de Medicina Integral Prof. Fernando Figueira. Read More

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http://dx.doi.org/10.1590/1806-9282.64.08.692DOI Listing
August 2018
1 Read

Width of sulcus and thickness of gyrus in patients with cerebral atherosclerosis: a new tool for the prevention of vascular cognitive impairment.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):684-691

. PhD in Pathology, Professor of Postgraduate Course Health Sciences, Universidade Federal do Triângulo Mineiro (UFTM), Uberaba (MG), Brasil.

Background And Purpose: Cerebral atherosclerosis is the main cause of lesions that contribute to vascular cognitive impairment and vascular dementia, followed by arteriosclerosis of small vessels and cerebral amyloid angiopathy. The purpose of this study was to compare the post-mortem radiological alterations of autopsied adults with the macroscopic alterations in the posterior region of these brains in order to establish a relationship between the two forms of analysis and to discuss the relevance of the prevention of vascular cognitive impairment in patients with encephalic atherosclerosis.

Materials And Methods: Thirteen brains were analysed macroscopically to assess the degree of atherosclerosis of the basilar and the posterior cerebral arteries. Read More

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http://dx.doi.org/10.1590/1806-9282.64.08.684DOI Listing
August 2018
5 Reads

Rectal ulcer due to Kayexalate deposition - an unusual case.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):680-683

. Internal Medicine Department, Medicine Service III - Santarém Hospital - Santarém, Santarém, Portugal.

Sodium polystyrene sulfonate (PSP) or Kayexalate is a cation-exchange resin, widely used in the management of hyperkalaemia due to renal disease. A rare, yet potentially dangerous, adverse event related to sodium polystyrene sulfonate use is intestinal mucosal injury, especially in the colon. The injury to the gastrointestinal mucosa can range from mild and superficial to wall necrosis and bowel perforation. Read More

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http://dx.doi.org/10.1590/1806-9282.64.08.680DOI Listing
August 2018
3 Reads

Spinal metallosis as a complication of a lodged bullet from a firearm wound: an image-centered case.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):676-679

Department of Radiology and Imaging, DOCUMENTA, São Francisco Hospital, Ribeirão Preto, SP, Brasil.

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http://dx.doi.org/10.1590/1806-9282.64.08.676DOI Listing
August 2018
1 Read

A rare cause of acute abdomen in an elderly patient.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):670-671

. Department of Internal Medicine, São Francisco Hospital, Ribeirão Preto, São Paulo, Brasil.

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http://dx.doi.org/10.1590/1806-9282.64.08.670DOI Listing
August 2018
1 Read

Ion mobility spectrometry: the diagnostic tool of third millennium medicine.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):861-868

. Medical Subdirector, Organización Clínica Bonnadona Prevenir, Barranquilla, Atlantico, Colombia.

Ion mobility spectrometry (IMS) is a fast, low cost, portable, and sensitive technique that separates ions in a drift tube under the influence of an electric field according to their size and shape. IMS represents a non-invasive and reliable instrumental alternative for the diagnosis of different diseases through the analysis of volatile metabolites in biological samples. IMS has applications in medicine in the study of volatile compounds for the non-invasive diagnose of bronchial carcinoma, chronic obstructive pulmonary disease, and other diseases analysing breath, urine, blood, faeces, and other biological samples. Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.861DOI Listing
September 2018
2 Reads
0.915 Impact Factor

Efficacy and Safety of PARACHUTE® Device: systematic review.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):853-860

. Postgraduate Program in Health Technology Assessment of the Instituto Nacional de Cardiologia, Rio de Janeiro, RJ, Brasil.

Introduction: Heart failure due to an acute myocardial infarction is a very frequent event, with a tendency to increase according to improvements in the treatment of acute conditions which have led to larger numbers of infarction survivors.

Objective: The aim of this study is to synthesize the evidence, through a systematic review, on efficacy and safety of the device in patients with this basic condition.

Methods: Studies published between January 2002 and October 2016 were analysed, having as reference databases Embase, Medline, Cochrane Library, Lilacs, Web of Science and Scopus. Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.853DOI Listing
September 2018
1 Read

The relationship between malnutrition and quality of life in haemodialysis and peritoneal dialysis patients.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):845-852

. University of Health Sciences, Izmir Tepecik Health Research and Application Center - Department of Family Medicine, Yenişehir/İzmir, Turkey.

Background: One of the most important factors affecting the quality of life of chronic kidney disease (CKD) patients is nutrition. Prevention of malnutrition increases patients' quality and length of life. In this study, we aimed to determine the frequency of malnutrition, quality of life, and the relationship between them in patients with end-stage renal disease (ESRD). Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.845DOI Listing
September 2018

Malnutrition associated with inflammation in the chronic renal patient on hemodialysis.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):837-844

. Universidade Federal de Pernambuco, Recife, PE, Brasil.

Introduction: Malnutrition-Inflammation-Atherosclerosis Syndrome is very frequent in patients with chronic kidney disease on haemodialysis. In these patients, the inflammation associated with malnutrition is observed by the Malnutrition-Inflammation Score.

Objective: To analyse the relationship between malnutrition-inflammation-atherosclerosis syndrome and anthropometric and biochemical parameters of patients on haemodialysis. Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.837DOI Listing
September 2018
1 Read

Palliative approach in acute neurological events: a five-year study.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):833-836

. Graduate Assistant in Internal Medicine, Coordinator of the In-hospital Team for Palliative Care Support of the Santo António Hospital, Porto Hospital Centre, Porto, Portugal.

Introduction: Acute neurological illness often results in severe disability. Five-year life expectancy is around 40%; half the survivors become completely dependent on outside help.

Objective: Evaluate the symptoms of patients admitted to a Hospital ward with a diagnosis of stroke, subarachnoid hemorrhage or subdural hematoma, and analyze the role of an In-Hospital Palliative Care Support Team. Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.832DOI Listing
September 2018
2 Reads

Home-based exercise therapy for treating non-specific chronic low back pain.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):824-831

. Medical Doctor at the Department of Orthopedics and Traumatology of Unifesp/EPM - São Paulo (SP), Brasil. Doctor at the Albert Einstein Israelite Hospital, São Paulo (SP), Brasil.

Objective: To evaluate pain, functional capacity, and quality of life of patients with non-specific chronic low back pain, after home-based exercise therapy with different kinds of supervision.

Method: Thirty individuals of both gender, between 18 and 65 years old, performed the proposed exercises three times a week, for eight weeks. Group A (N = 17) performed the exercises after a single supervised session. Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.824DOI Listing
September 2018
1 Read

Effect of generalized ligamentous hyperlaxity related of quality of life in the foot: a case controlled study.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):819-823

. Department, Faculty of Health Sciences, Universidad de León, Ponferrada, León, Spain.

Generalized ligamentous hyperlaxity (GLH) has been shown to predispose an individual to a number of orthopaedic conditions. Little is known about how GLH affects people' foot health-related quality of life. This study analyses a sample of people with GLH and people without GLH with normalised reference values of the scores collected with regard to using the Foot Health Status Questionnaire (FSHQ). Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.819DOI Listing
September 2018
1 Read

Epidemiological profile of Brazilian oncological patients seen by a reference oncology center of the public health system and who migrate in search of adequate health care.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):814-818

. ABC School of Medicine (Faculdade de Medicina do ABC - FMABC), Santo André, São Paulo, Brasil.

Introduction: Structural disparities between different Brazilian regions in public health system cause patients to migrate in search of better conditions to treat their diseases. Besides patient's discomfort, there is a concentration of care in large centres, causing overload to current capacity.

Objective: To evaluate migratory flow and associated factors in a reference service in oncology. Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.814DOI Listing
September 2018
1 Read

Interns' depressive symptoms evolution and training aspects: a prospective cohort study.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):806-813

. MD, PhD. Affiliated Professor, Department Psychiatry, Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo (SP), Brasil.

Objective: To study depression symptoms' incidence of medical interns (first year of medical residency) and its correlation with occupational characteristics, satisfaction and stress about their training program.

Methods: Prospective Cohort Study conducted at Escola Paulista de Medicina, Universidade Federal de São Paulo. First year residents, N = 166, from a teaching hospital were invited to answer the Beck Depression Inventory (BDI) and an occupational questionnaire in a prospective longitudinal study. Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.806DOI Listing
September 2018
1 Read

Dialogue between primary and secondary health care providers in a Brazilian hypertensive population.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):799-805

. Núcleo Interdisciplinar de Estudos e Pesquisas em Nefrologia (Niepen), Juiz de Fora (MG), Brasil.

Objective: To describe clinical and epidemiological profiles of patients with hypertension referred to a secondary care unit and to assess the adequacy of the referral criteria.

Method: This descriptive transversal study analysed 943 hypertensive patients referred to a secondary healthcare unit from September 2010 to August 2012. Clinical and sociodemographic data as well as data regarding the liaison between secondary and primary care services were collected. Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.799DOI Listing
September 2018
1 Read

Multiple factors affect the regeneration of liver.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):791-798

. Department of Hepatobiliary Surgery, Affiliated Cancer Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Objective: To study factors affecting the liver regeneration after hepatectomy.

Methods: With 3D reconstitution technology, liver regeneration ability of 117 patients was analysed, and relative factors were studied.

Results: There was no statistically difference between the volume of simulated liver resection and the actual liver resection. Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.791DOI Listing
September 2018
2 Reads

Light chain cardiac amyloidosis - a rare cause of heart failure in a young adult.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):787-790

. Department of Cardiology, Hospital Distrital de Santarém, Santarém, Portugal.

Cardiac amyloidosis is an infiltrative cardiomyopathy, resulting from amyloid deposition within the myocardium. In primary systemic (AL-type) amyloidosis, the amyloid protein is composed of light chains resulting from plasma-cell dyscrasia, and cardiac involvement occurs in up to 50% of the patients We present a case of a 43-year-old man, with complaints of periodical swollen tongue and xerostomia, bleeding gums and haematuria for two months. His blood results showed normocytic anaemia, thrombocytopenia and a high spontaneous INR, therefore he was referred to the Internal Medicine clinic. Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.787DOI Listing
September 2018
3 Reads

CULPRIT-SHOCK study.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):783-786

. Department of Atherosclerosis, Heart Institute (InCor), University of São Paulo, São Paulo, Brazil.

The treatment of patients with ST-segment elevation myocardial infarction concomitant with the presence of multivessel disease has been studied in several recent studies with the purpose of defining the need, as well as the best moment to approach residual lesions. However, such studies included only stable patients. The best therapeutic approach to cardiogenic shock secondary to acute coronary syndrome, however, remains controversial, but there are recommendations from specialists for revascularization that include non-event related injuries. Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.783DOI Listing
September 2018
3 Reads

Lumbar herniated disc treatment with percutaneous hydrodiscectomy.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):778-782

. Lecturer Professor of School of Medicine of USP; São Paulo, SP, Brasil.

Lumbar herniated disc are common manifestations of degenerative spine diseases, the main cause of radiated lower back pain. This guideline followed standard of a systematic review with recovery of evidence based on the movement of evidence-based medicine. We used the structured method for formulating the question synthesized by the acronym p. Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.778DOI Listing
September 2018
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Recommendations for hypofractionated whole-breast irradiation.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):770-777

. Centro de Tratamento em Radio-Oncologia (CTR) and Ribeirão Preto Medical School (FMRP) da Universidade de São Paulo (USP) - Ribeirão Preto/SP; Hospital Márcio Cunha (HMC) - Ipatinga/MG, Brasil.

This recommendation consensus for hypofractionated whole-breast radiotherapy (RT) was organized by the Brazilian Society of Radiotherapy (SBRT) considering the optimal scenario for indication and safety in the technology applied. All controversies and contraindication matters (hypofractionated RT in patients who underwent chemotherapy [CT], hypofractionated RT in lymphatic drainage, hypofractionated RT after mastectomy with or without immediate reconstruction, boost during surgery, hypofractionated RT in patients under 50 years old, hypofractionated RT in large breasts, hypofractionated RT in histology of carcinoma in situ [DCIS]) was discussed during a meeting in person, and a consensus was reached when there was an agreement of at least 75% among panel members. The grade for recommendation was also suggested according to the level of scientific evidence available, qualified as weak, medium, or strong. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/1806-9282.64.09.770DOI Listing
September 2018
4 Reads

Homeopathy: scientific or not?

Rev Assoc Med Bras (1992) 2018 09;64(9):769

. Visiting professor, Hainan Medical University, Haikou, Hainan, China.

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http://dx.doi.org/10.1590/1806-9282.64.09.769DOI Listing
September 2018
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Phytotherapy: yesterday, today, and forever?

Rev Assoc Med Bras (1992) 2018 09;64(9):765-768

. Full Professor of Disciplina de Ginecologia do Departamento de Obstetrícia e Ginecologia, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo USP, São Paulo/SP, Brasil.

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http://dx.doi.org/10.1590/1806-9282.64.09.765DOI Listing
September 2018
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Mapping the scientific research on the negative aspects of the medical school learning environment.

Rev Assoc Med Bras (1992) 2018 Nov;64(11):1050-1057

School of Medicine, Federal University of Juiz de Fora, Juiz de Fora, MG, Brasil.

Objective: We sought to understand the landscape of published articles regarding medical schools' learning environments (LE) worldwide, with an explicit focus on potentially negative aspects of the LE as an effort to identify areas specifically in need of remediation or intervention that could prevent future unprofessional behaviours, burnout, violence and mistreatment among students and physicians.

Methods: A bibliometric analysis was conducted in six electronic databases (PubMed/Medline, Web of Science, Cochrane Library, SCOPUS, ERIC-ProQuest and PsycINFO) through December 31, 2016, including 12 themes: learning environment - general, hidden curriculum (negative), unethical behaviours, bullying/hazing, violence, sexual discrimination, homophobia, racism, social discrimination, minorities' discrimination, professional misconduct, and "other" negative aspects.

Results: Of 9,338 articles found, 710 met the inclusion criteria. Read More

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http://dx.doi.org/10.1590/1806-9282.64.11.1050DOI Listing
November 2018
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Normal delivery and cesarean section: cost per brazilian regions, 2015.

Rev Assoc Med Bras (1992) 2018 Nov;64(11):1045-1049

Universidade Federal do Rio Grande do Sul, Social Medicine Department, Porto Alegre, RS, Brasil.

Objective: To describe the number of funds made by the Brazilian National Health System to normal delivery and cesarean procedures, according to the Brazilian regions in 2015, and estimate the cost cutting if the recommendation concerning the prevalence of cesarean deliveries by the World Health Organization (10 to 15%) were respected.

Methods: Secondary analysis of data from the Hospital Information System of the Brazilian National Health System. The variables considered were the type of delivery (cesarean section and normal), geographic region of admission, length of stay and amount paid for admission in 2015. Read More

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http://dx.doi.org/10.1590/1806-9282.64.11.1045DOI Listing
November 2018
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Health-related quality of life in a cohort of youths with type 1 diabetes.

Rev Assoc Med Bras (1992) 2018 Nov;64(11):1038-1044

Universidade Federal do Paraná, Pediatric Endocrinology Unit, Department of Pediatrics, Hospital de Clínicas, Curitiba, PR, Brasil.

Objective: Health-related quality of life (HRQOL) in type 1 diabetes mellitus (T1DM) has been widely studied. The objectives of this study were to evaluate and identify the factors influencing the HRQOL of children and adolescents with T1DM.

Material And Methods: In total, 59 patients (9-16 years, T1DM for ≥1 year) responded to a version of the Diabetes Quality of Life Instrument for Youth (DQOLY) adapted to adapted to Brazilian patients, the Instrumento de Qualidade de Vida para Jovens com Diabetes (IQVJD). Read More

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http://dx.doi.org/10.1590/1806-9282.64.11.1038DOI Listing
November 2018
11 Reads

The role of neonatal screening in nutritional evolution in the first 12 months after diagnosis of cystic fibrosis.

Rev Assoc Med Bras (1992) 2018 Nov;64(11):1032-1037

Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brasil.

Objective: to assess the progression of pediatric cystic fibrosis (CF) patients' nutritional status during the first 12 months after diagnosis and to establish its association with neonatal screening and clinical variables. Patients were recruited from two reference centers in Southern Brazil.

Methods: Retrospective cohort study was carried out with all the patients diagnosed between 2009 and 2014. Read More

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http://dx.doi.org/10.1590/1806-9282.64.11.1032DOI Listing
November 2018
2 Reads