3,486 results match your criteria Retroperitoneal Fibrosis


The combination of microRNA-371a-3p and 375-5p can distinguish viable germ cell tumor and teratoma from necrosis in postchemotherapy retroperitoneal lymph node dissection specimens.

Transl Androl Urol 2021 Apr;10(4):1647-1655

Department of Urology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.

Background: To identify a combination of microRNAs (miRNA) to differentiate between viable tumor (V) or teratoma (T) and necrosis/fibrosis (N) in pcRPLND specimens of metastatic germ cell tumor (GCT) patients with residual masses ≥1 cm after chemotherapy. Biomarker guided therapy could reduce overtreatment with pcRPLND in patients with only N.

Methods: We selected 48 metastatic GCT patients who had undergone pcRPLND. Read More

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Outcomes of post-chemotherapy robot-assisted retroperitoneal lymph node dissection in testicular cancer: multi-institutional study.

World J Urol 2021 May 7. Epub 2021 May 7.

Department of Urology, Naval Medical Center San Diego, San Diego, CA, USA.

Objective: To evaluate the perioperative and oncological outcomes after post-chemotherapy robot-assisted retroperitoneal lymph node dissection (PC-RARPLND).

Materials And Methods: We retrospectively reported the perioperative and oncological outcomes of all the patients with testicular cancer who underwent PC-RARPLND at three tertiary teaching centers. Descriptive statistical measures were used to report demographic, clinical, intraoperative, postoperative and oncological outcomes. Read More

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Management of long ureteral stenosis: Alternatives to indwelling ureteral stents.

Prog Urol 2021 Apr 30. Epub 2021 Apr 30.

Department of Urology and Transplant surgery, Hôpital Européen Georges-Pompidou, AP-HP, University of Paris Descartes, Paris, France.

Objectif: Evaluate kidney autotransplantation (KAT) and ileal ureter substitution (IUS) practice and outcome as alternatives to indwelling ureteral stents for the management of long ureteral stenosis (US).

Material: We included all patients treated for US with KAT or IUS in 5 French university urology centers between 2010 and 2018. We excluded US due to urothelial carcinoma. Read More

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[Retroperitoneal fibrosis at the Ibn Sina University Hospital of Rabat: about 18 cases].

Pan Afr Med J 2021 10;38:149. Epub 2021 Feb 10.

Service d´Urologie B, CHU Ibn Sina de Rabat, Rabat, Maroc.

Retroperitoneal fibrosis (RPF) is a rare disease characterized by the formation of a fibro-inflammatory plaque in the retroperitoneal space in front of the abdominal aorta. It is responsible for the sheathing of the ureters. It is characterized by unspecific clinical signs, and it is often detected based on obstructive uropathy. Read More

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Value of contrast-enhanced ultrasonography in assessing the activity of idiopathic retroperitoneal fibrosis: a prospective study.

Clin Exp Rheumatol 2021 Apr 15. Epub 2021 Apr 15.

Department of Rheumatology, The First Medical Center of PLA General Hospital, Beijing, China.

Objectives: We aimed to evaluate changes in the contrast-enhanced ultrasound (CEUS) parameters in patients with idiopathic retroperitoneal fibrosis (RPF) before and after treatment, and to analyse the value of CEUS to assess RPF activity.

Methods: We performed a prospective study that included patients with idiopathic RPF who were treated for RPF at our hospital from April 2016 to April 2019. All patients underwent CEUS examination and some of them underwent positron emission tomography/computed tomography (PET/CT) examination simultaneously. Read More

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IgG4-Related Retroperitoneal Fibrosis: A Rare Association With Riedel's Thyroiditis.

Cureus 2021 Mar 19;13(3):e13997. Epub 2021 Mar 19.

Endocrinology, Diabetes and Metabolism, Sanford Health, Fargo, USA.

Idiopathic retroperitoneal fibrosis is a rare fibro-inflammatory disease that can be associated with other IgG4-related diseases (IgG4-RDs). It is exceedingly uncommon to encounter this condition in a patient with Riedel's thyroiditis (RT), another disease in the IgG4-RD family. We present the case of a 53-year-old man with a history of RT who presented for severe localized lower abdominal and suprapubic pain due to obstructive uropathy from extensive retroperitoneal fibrosis. Read More

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Renal Involvement in IgG4-Related Disease: From Sunlight to Twilight.

Front Med (Lausanne) 2021 31;8:635706. Epub 2021 Mar 31.

Clinical Immunology and Allergy Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

IgG4-Related Disease (IgG4-RD) is a fibroinflammatory condition characterized by a typical histopathological pattern (dense lymphoplasmacytic infiltrate with prevalent IgG4+ plasma cells and storiform fibrosis), which may involve the kidney both directly (IgG4-related kidney disease, IgG4-RKD) or indirectly, as a consequence of post-renal ureteral obstruction due to retroperitoneal fibrosis (IgG4-RD RF). The most frequent presentation of IgG4-RKD is IgG4-related tubulointerstitial nephritis (TIN), but a glomerular disease can be present, in most of the cases a membranous nephropathy. Albeit steroid-responsive, in some cases renal manifestations may lead to progressive and permanent organ damage. Read More

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Subcutaneous nephrovesical bypass in a patient with advanced prostate cancer.

Urol Case Rep 2021 Sep 26;38:101656. Epub 2021 Mar 26.

Department of Urology, Medical University Pleven, Bulgaria.

In the presence of hydronephrosis, as a result of ureteral malignant invasion, advanced pelvic tumor or retroperitoneal fibrosis, we most often perform a double J stent or percutaneous nephrostomy. In the search for a better quality of life for our patients in recent years in urological practice is increasingly becoming the use of subcutaneous nephrovesical bypass due to its proven safety, effectiveness and minimal invasiveness. Read More

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September 2021

Misplacement of DJ stent into inferior vena cava in a patient with retroperitoneal fibrosis, a case report.

Urol Case Rep 2021 Sep 23;38:101650. Epub 2021 Mar 23.

Men's Health and Reproductive Health Research Center (IRHRC), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Intravascular migration of DJ stent is a rare complication that needs immediate attention to prevent severe complication. We reported a rare case of intravascular migration of DJ stent in a patient with retroperitoneal fibrosis. The DJ stent was removed by cystoscopy with no complication. Read More

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September 2021

Malignant Lymphoma Mimicking Retroperitoneal Fibrosis.

Intern Med 2021 Apr 19. Epub 2021 Apr 19.

Department of Internal Medicine, Keiaido Hospital, Japan.

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IgG4-related kidney disease: Pathogenesis, diagnosis, and treatment.

Clin Nephrol 2021 Apr 16. Epub 2021 Apr 16.

IgG4-related disease (IgG4-RD) is a recently recognized multisystem disease characterized by lymphoplasmacytic inflammation and fibrosis in affected tissues that can affect several organs including the kidney, the involvement of which is often manifested by tubulointerstitial nephritis. The pathogenic mechanisms of IgG4-RD are divided into two sections: one focused on potential initiation mechanisms, particularly genetic, and the other on specific pathological pathways. For the specific pathological pathways, cellular immunity, particularly T-cell mediated immunity, has been implicated in the pathogenesis of IgG4-RD. Read More

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Imaging of ureter: a primer for the emergency radiologist.

Emerg Radiol 2021 Apr 13. Epub 2021 Apr 13.

Department of Radiology, University of Texas Health, San Antonio, TX, USA.

In this review article, we will discuss the gamut of abnormalities involving the ureters. In the emergency department, ureterolithiasis is the most common indication for imaging abdomen and pelvis. However, spectrum of ureteral abnormalities including congenital, infectious and inflammatory, primary and secondary ureteral malignancies, retroperitoneal fibrosis rare described in this article may be encountered. Read More

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The value of (18)F-FDG PET/CT in Diagnosis and Evaluation of Response to Treatment in Retroperitoneal Fibrosis.

Nuklearmedizin 2021 Apr 9. Epub 2021 Apr 9.

Nuclear Medicine, Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey.

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The Resonance and the Allium ureteral stents in the treatment of non-malignant refractory ureterostenosis.

BMC Urol 2021 Apr 7;21(1):53. Epub 2021 Apr 7.

Department of Urology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.

Background: Refractory non-malignant ureterostenosis is challenging to treat. The experience to treat the stenosis primarily cause by retroperitoneal fibrosis with the Resonance and Allium metallic stent is still limited. We aim to evaluate the efficacy and safety of these two stents and provide alternative treatment options. Read More

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[A total replacement of the both ureters and urinary bladder by ileal conduit in a woman with contracted bladder and Ormonds disease].

Urologiia 2021 Mar(1):107-111

Department of urology of North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia.

A description of the successful surgical treatment of a patient with irreversible changes in both ureters and bladder resulting from a severe form of Ormond's disease and interstitial cystitis, resulting in contracted bladder, is presented. For the first time in clinical practice, a one-stage cystectomy, a bilateral ureterectomy with complete replacement of both ureters and the bladder with two isoperistaltic small bowel segment was performed. The postoperative course was uneventful. Read More

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IgG4-Related Disease Retroperitoneal Fibrosis: An Unusual Cause of Low Back Pain.

Cureus 2021 Feb 28;13(2):e13608. Epub 2021 Feb 28.

Internal Medicine, Hackensack University Medical Center - Palisades Medical Center, North Bergen, USA.

IgG4-related disease (IgG4-RD) is a cluster of rare fibroinflammatory diseases that more commonly affect organs such as major salivary glands, biliary tree, periorbital tissues, kidneys, lungs, lymph nodes, retroperitoneum, and less frequently, meninges, aorta, prostate, thyroid gland, pericardium, and the skin. The clinical picture mainly depends on the affected organ and the effects on the surrounding organs, however, the histopathologic findings are very similar regardless of the organ affected. Most patients have a subclinical presentation of the disease and the only clinical manifestation is related to the anatomic location of the disease, whereas some patients may have constitutional symptoms such as weight loss and are often misdiagnosed as having other pathologies (i. Read More

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February 2021

Characteristics of Adult Patients with Idiopathic Retroperitoneal Fibrosis and Assessment of Risk of Relapse at Diagnosis.

J Clin Med 2021 Mar 30;10(7). Epub 2021 Mar 30.

Department of Internal Medicine, Besancon University Hospital, 25000 Besancon, France.

Objectives: To compare adult patients' characteristics suffering from idiopathic retroperitoneal fibrosis between "relapse-free" and relapsing patients at the diagnosis and identify factors associated with relapse at initial presentation.

Methods: We conducted a retrospective multicentric study in four hospitals in Eastern France, from 1993 to 2020, of adult patients suffering from idiopathic retroperitoneal fibrosis. We analyzed clinical, biological, and radiological features at diagnosis and during a forty-month follow-up. Read More

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Clinical features and relapse risks of IgG4-related ophthalmic disease: a single-center experience in China.

Arthritis Res Ther 2021 03 31;23(1):98. Epub 2021 Mar 31.

Department of Rheumatology and Immunology, Peking University People's Hospital, 11 Xizhimen South Street, Beijing, 100044, China.

Background: IgG4-related ophthalmic disease (IgG4-ROD) is one of the phenotypes of IgG4-related disease (IgG4-RD), and its lesions are mainly located in the ocular. Currently, there are few studies on IgG4-ROD and no study has compared the phenotypic differences between IgG4-ROD and non IgG4-ROD (nIgG4-ROD). Thus, it is difficult to establish the optimal treatment strategy for IgG4-ROD. Read More

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A case of idiopathic retroperitoneal fibrosis presenting as gallbladder carcinoma.

BMC Surg 2021 Mar 25;21(1):162. Epub 2021 Mar 25.

Department of Surgery, Changxing People's Hospital, No. 66, Taihu Road, Changxing, Huzhou, 313100, Zhejiang, China.

Background: Retroperitoneal fibrosis (RPF) is a rare disease with a poor prognosis characterized by systemic inflammation and fibroinflammatory tissue. Idiopathic RPF (IRPF) accounts for approximately two-thirds of RPF cases.

Case Presentation: A 56-year-old female patient with abdominal distension was admitted to Changxing Hospital. Read More

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[The 487th case: prominent eyes, headache, blurred vision].

Zhonghua Nei Ke Za Zhi 2021 Apr;60(4):388-392

Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education,China National Clinical Research Center for Dermatologic and Immunologic Disease, Beijing 100730,China.

One 51 years old man was admitted to the rheumatology department with a history of prominent eyes, headache and blurred vision for half year. The main manifestations included retrobulbar inflammatory pseudotumor and retroperitoneal fibrosis. He was initially diagnosed as granulomatosis with polyangiitis. Read More

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Oncology and complications.

Arch Ital Urol Androl 2021 Mar 19;93(1):71-76. Epub 2021 Mar 19.

Urology Department, General Hospital of Athens "G. Gennimatas", Athens.

This collection of cases describes some unusual urological tumors and complications related to urological tumors and their treatment. Case 1: A case of uretero-arterial fistula in a patient with long-term ureteral stenting for ureteral oncological stricture and a second case associated to retroperitoneal fibrosis were described. Abdominal CT, pyelography, cystoscopy were useful to show the origin of the bleeding. Read More

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The Association of Smoking with IgG4-Related Disease: A Case-Control Study.

Rheumatology (Oxford) 2021 Mar 5. Epub 2021 Mar 5.

Rheumatology Unit, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA.

Objective: To evaluate the association between cigarette smoking and the odds of IgG4-related disease (IgG4-RD).

Methods: We performed a case-control study of patients with IgG4-RD, compared in a 1:5 ratio with age-, race- and sex-matched controls. We included cases evaluated at Massachusetts General Hospital, a hospital within the Mass General Brigham (MGB) System. Read More

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A rare case of a cystic renal mass with heterotopic ossification and a mini literature review.

J Xray Sci Technol 2021 Mar 15. Epub 2021 Mar 15.

Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Introduction: It is a challenge to make accurate pre-surgical diagnosis for renal tumors. This study is to report the findings, management, and outcome of one rare case of ossification in a cystic renal mass. We present and discuss the pathological characteristics, radiologic features, and treatment alternatives of the patient. Read More

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Anti-PD-1 associated retroperitoneal fibrosis.

Rheumatology (Oxford) 2021 Mar 17. Epub 2021 Mar 17.

Department of Oncology, Olympion General Clinic, Patras, Greece.

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Including Medical Management in the Urologic Approach to Idiopathic Retroperitoneal Fibrosis.

Urology 2021 Mar 11. Epub 2021 Mar 11.

Department of Urology, Michigan Medicine.

Objective: To characterize the timing and effectiveness of medical management in resolving stent-dependent ureteral compression secondary to idiopathic retroperitoneal fibrosis (RPF), the long-term relevant outcomes, and the side effects of treatment.

Methods: A retrospective review of RPF patients diagnosed from 2002-2018 was performed. Patients with hydronephrosis due to ureteral involvement that were managed with medication and with temporary stenting as needed, but without initial ureterolysis, were included. Read More

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An enigmatic case of IgG4-related nephropathy and an updated review of the literature.

Clin Exp Med 2021 Mar 8. Epub 2021 Mar 8.

Division of Nephrology, Dialysis and Renal Transplantation, ASST Grande Ospedale Metropolitano Niguarda, 20162, Milan, Italy.

IgG4-related disease (IgG4-RD) is still an underestimated disorder which affects multiple organs, and its recognition as a distinct clinical disease has been only proved in the recent decades. The renal involvement has been documented in approximately 15% of patients with IgG4-RD, and the typical manifestation is a tubulo-interstitial nephritis. The main histological findings in IgG4-RD are typically a dense tissue infiltration of IgG4-positive plasma cells, storiform fibrosis, obliterative phlebitis, and frequently elevated IgG4 serum levels. Read More

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Laparoscopic partial sacrocolpopexy mesh resection due to mesh infection.

Int Urogynecol J 2021 Mar 3. Epub 2021 Mar 3.

Obstetrics & Gynecology, Hospital Universitari Son Llàtzer, Carretera de Manacor Km 4, 07198, Palma de Mallorca, Balearic Islands, Spain.

Purpose: Sacrocolpopexy is considered the gold-standard procedure for apical compartment prolapse and has become a widely used intervention strategy. The mesh material used in the surgical treatment of pelvic organ prolapse is associated with significant complications in some cases, frequently managed conservatively but sometimes necessitating mesh excision for symptom relief.

Methods: In this video we present the case of a 49-year-old woman who after sacrocolpopexy reported foul-smelling discharge as the only symptom. Read More

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Idiopathic Retroperitoneal Fibrosis.

Chirurgia (Bucur) 2021 Jan-Feb;116(1):117-123

The world of surgery has been concerned with idiopathic retroperitoneal fibrosis (RPF) ever since 1948, when J. K. Ormond published the first case of ureteral stenosis following a retroperitoneal scleroinflammatory process due to unknown reasons. Read More

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