3,589 results match your criteria Retroperitoneal Fibrosis


A case of IgG4-related retroperitoneal fibrosis with significant involvement of the abdominal aorta-a clinical and diagnostic challenge.

J Vasc Surg Cases Innov Tech 2022 Jun 8;8(2):275-280. Epub 2022 Mar 8.

Department of Vascular and Endovascular Surgery, Waikato Hospital, Hamilton, New Zealand.

Immunoglobulin (Ig)G4-related disease (IgG4-RD) with retroperitoneal fibrosis (RPF) is a rare, fibroinflammatory disease involving the soft tissues of the retroperitoneum. A 73-year-old man with IgG4-related RPF affecting the abdominal aorta and iliac arteries was treated with steroids and mycophenolate mofetil. The prevalence of the disease remains unknown because it is often misdiagnosed and can mimic many malignant, infectious, and inflammatory conditions. Read More

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[Chronic Periaortitis].

Authors:
Mike Becker

Ther Umsch 2022 Jun;79(5):254-259

Klinik für Rheumatologie, Universitätsspital Zürich.

Chronic Periaortitis The term chronic periaortitis encompasses several fibroinflammatory diseases that manifest on or around the abdominal aorta which may be associated with aneurysm formation. Formerly distinct entities are grouped together, such as idiopathic retroperitoneal fibrosis (Ormond's disease), inflammatory aortic aneurysm, and perianeurysmal retroperitoneal fibrosis. They may also occur IgG4-related. Read More

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Urothelial carcinoma of the proximal ureter revealed by spontaneous forniceal rupture: A case report.

Urol Case Rep 2022 Jul 2;43:102098. Epub 2022 May 2.

Urology Department FSI Hospital, Tunis, Tunisia.

Spontaneous rupture of the upper urinary tract is a rare and potentially serious pathology. Lithiasis is the most frequent cause. However, other causes are incriminated such as trauma, retroperitoneal fibrosis and especially stenosing tumors. Read More

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A Unified Serum IgG4 Cutoff Level for the Diagnosis of IgG4-Related Disease Using a Wide Array of Kits.

Mod Rheumatol 2022 May 16. Epub 2022 May 16.

Department of Clinical Laboratory, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.

Objectives: An IgG4 level above 1350 mg/L is one of the comprehensive criteria for the diagnosis of IgG4-related disease (IgG4-RD). The purpose of this study was to evaluate the differences in IgG4 levels determined using reagents from two main manufacturers and their concordance with clinical diagnosis.

Methods: IgG4 levels were measured in 309 patients, including 146, 40, 42, 41, and 40 patients with untreated IgG4-RD, pancreatic cancer, primary Sjogren syndrome, systemic lupus erythematosus, and idiopathic retroperitoneal fibrosis, respectively, and 141 healthy controls. Read More

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Retroperitoneal fibrosis with gastric outlet obstruction managed by endoscopic ultrasonography-guided gastroenterostomy.

Dig Endosc 2022 May 10. Epub 2022 May 10.

Department of Medical Gastroenterology, Asian Institute of Gastroenterology, AIG Hospitals, Hyderabad, India.

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The contribution of the immune system to genitourinary fibrosis.

Exp Biol Med (Maywood) 2022 May 7:15353702221090872. Epub 2022 May 7.

Department of Urology, University of Rochester Medical Center, Rochester, NY 14642, USA.

Fibrotic diseases of the genitourinary tract are devastating and incompletely understood pathologies. These diseases include urethral and ureteral strictures, retroperitoneal fibrosis, and Peyronie's disease. They can contribute to obstructive uropathy and sexual dysfunction. Read More

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Comparison of laparoscopic and open ureterolysis for retroperitoneal fibrosis: Results from a tertiary referral center.

J Endourol 2022 May 6. Epub 2022 May 6.

Istanbul University- Cerrahpasa, Cerrahpasa School of Medicine, Department of Urology, Osmaniye Fildami Araligi Sok., Fildami Sitesi, A-Blok, No: 20, Istanbul, Turkey, 34144.

Objectives: To compare the surgical outcomes of open and laparoscopic ureterolysis procedures in patients requiring surgical treatment for ureteral obstruction caused by retroperitoneal fibrosis.

Materials: This study was designed retrospectively. The clinical records of patients who underwent ureterolysis between January 2005 and April 2019 due to ureteral obstruction caused by retroperitoneal fibrosis were examined. Read More

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Psoas hitch procedure in 166 adult patients: The largest cohort study before the laparoscopic era.

BJUI Compass 2021 Sep 6;2(5):331-337. Epub 2021 Apr 6.

Department of Urology University Medical Centre Utrecht Utrecht The Netherlands.

Objectives: To present the short-term and long-term outcomes of the psoas hitch procedure in a large cohort with long-term follow-up.

Patients And Methods: A multicenter, retrospective cohort study was conducted. Patients were included if they had undergone an open psoas hitch procedure with ureteral reimplantation for different types of distal ureteral pathology between 1993 and 2017. Read More

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September 2021

Retroperitoneal fibrosis, a rare entity with urorenal and vascular subtypes - preliminary data.

Ren Fail 2022 Dec;44(1):688-692

Department of Nephrology, Dialysis and Internal Diseases, Medical University of Warsaw, Warsaw, Poland.

Introduction: Retroperitoneal fibrosis (RPF) is a rare disease associated with the formation of hard inflammatory and fibrous tissue in the retroperitoneum. Taking into consideration the fact that RPF is a rare disease with different subtypes, we compared the basal clinical and biochemical characteristics of the vascular and urorenal subtypes.

Patients And Methods: From January 2005 until December 2021, 27 patients were identified as vascular subtype (18 males) and 11 as urorenal subtype (9 males). Read More

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December 2022

Transcriptome analysis of tumor-derived mesenchymal progenitor cells shows that is a fibrosis regulator of retroperitoneal liposarcoma.

Ann Transl Med 2022 Mar;10(6):360

Laboratory of Molecular Diagnosis and Regenerative Medicine, Medical Research Center, the Affiliated Hospital of Qingdao University, Qingdao, China.

Background: Retroperitoneal liposarcoma (RPLS) is a rare, biologically heterogeneous tumor with distinct clinical characteristics, such as frequent local recurrence, repeated relapse, and rare distant metastasis. No effective targeted therapy is available for RPLS. Here, we aim to determine the pathological functions and therapeutic potential of carbohydrate sulfotransferase 15 () in RPLS. Read More

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Thinking Beyond Acute Kidney Injury.

Case Rep Nephrol Dial 2022 Jan-Apr;12(1):16-21. Epub 2022 Mar 10.

Division of Nephrology, Department of Medicine, University of South Alabama, Mobile, Alabama, USA.

Acute kidney injury (AKI) can be a significant clue to solving a puzzling patient presentation. Postrenal AKI should be suspected if imaging shows any degree of hydronephrosis and can be caused by a variety of conditions. Diagnosis of urinary obstruction without significant dilatation of the pelvic-ureteral system requires a higher degree of suspicion, and hence, its identification can become late. Read More

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Overlooked issues in inferior vena cava reconstruction for deep venous thrombosis and retroperitoneal fibrosis.

J Vasc Surg Venous Lymphat Disord 2022 May;10(3):797

Cardiovascular Surgery İstanbul Medeniyet University Faculty of Medicine Göztepe Prof. Dr. Süleyman Yalçın City Hospital Istanbul, Türkiye.

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A 61-Year-Old Woman Presenting with Low Back Pain Diagnosed with IgG4-Related Disease Affecting the Thoracoabdominal Aorta and Retroperitoneum.

Am J Case Rep 2022 Apr 15;23:e935007. Epub 2022 Apr 15.

Department of Nuclear Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.

BACKGROUND Immunoglobulin G4-related disease (IgG4-RD) includes several immune-mediated fibro-inflammatory conditions affecting multiple organs. Increased IgG4 serum levels support the diagnosis of IgG4-RD and characteristic histopathology of fibrous infiltrates or masses containing IgG4-positive plasma cells. We present the case of a 61-year-old woman with low back pain who was diagnosed with IgG4-RD involving the thoracoabdominal aorta and retroperitoneum. Read More

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When idiopathic retroperitoneal fibrosis mimics Castleman disease: a challenging differential diagnosis.

BMJ Case Rep 2022 04 7;15(4). Epub 2022 Apr 7.

Pathology Unit, Azienda Ospedaliera Santa Maria di Terni, University of Perugia, Terni, Italy.

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Clinical significance of soluble interleukin-2 receptor measurement in patients with idiopathic retroperitoneal fibrosis.

Int Urol Nephrol 2022 Mar 31. Epub 2022 Mar 31.

Department of Internal Medicine/Dutch National Center of Expertise Retroperitoneal Fibrosis, Albert Schweitzer Hospital, PO Box 444, NL-3300 AK, Dordrecht, The Netherlands.

Background: Idiopathic retroperitoneal fibrosis (iRPF) is a rare chronic fibro-inflammatory disorder of unknown etiology. Activated T-helper cells, which shed soluble interleukin-2 receptor (sIL-2R) into the circulation, may play a pathogenetic role. Hence, measuring sIL-2R may be of value in monitoring disease activity and treatment response in iRPF patients. Read More

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The Challenges of Diagnosing Nondilated Obstructive Uropathy: A Case Report.

Can J Kidney Health Dis 2022 26;9:20543581221086683. Epub 2022 Mar 26.

Division of Nephrology, Rush University Medical Center, Chicago, IL, USA.

Rationale: Nondilated obstructive uropathy (NDOU) is a rare cause of acute renal failure reported in less than 5% of cases of obstructive uropathy. It is typically associated with intrapelvic malignancies and diseases causing retroperitoneal lymphadenopathy and retroperitoneal fibrosis. As these conditions may prevent radiographic dilation of the collecting system, the diagnosis of NDOU may be missed by usual diagnostic testing. Read More

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Gastric Signet-Ring-Cell Adenocarcinoma with Delayed Retroperitoneal Metastasis and Fibrosis.

Case Rep Oncol 2022 Jan-Apr;15(1):114-119. Epub 2022 Feb 14.

Discipline of Surgery, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland, Canada.

Gastric signet-ring-cell adenocarcinoma (SRCC) is a rare disease entity, often characterized by early age of the onset and sometimes attributable to heritable genetic mutations. Overall prognosis is usually poor due to diagnosis at late stages. There are a handful of case reports that describe patient presentation with retroperitoneal fibrosis secondary to malignancy from a concurrent gastric SRCC found on the workup. Read More

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February 2022

Comprehensive assessment and outcomes of patients with chronic periaortitis.

Clin Exp Rheumatol 2022 May 18;40(4):801-810. Epub 2022 Mar 18.

Division of Rheumatology, Department of Internal Medicine, Hacettepe University School of Medicine, Ankara, and Hacettepe Universitiy Vasculitis Research Center (HUVAC), Hacettepe University, Ankara, Turkey.

Objectives: Chronic periaortitis (CP) is a less known but more frequently diagnosed fibro-inflammatory disorder, but we know little about it and data regarding follow-up and outcome are still very limited. This study aims to identify the clinicopathologic, laboratory, and radiologic features, as well as outcomes of CP patients.

Methods: Patients with CP from HUVAC database were included in the study. Read More

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Case of bilateral hydronephrosis and spontaneous ureteral rupture as a rare complication of prostate biopsy.

Urol Case Rep 2022 Jul 17;43:102056. Epub 2022 Mar 17.

Department of Urology, University Hospital Nitra, Špitálska 6, 949 01, Nitra, Slovakia.

Development of bilateral hydronephrosis and ureteric rupture has never been reported in the published literature so far. We describe a case of 51years old gentleman who developed this complication after-rectal ultrasound guided prostate biopsy. The patient was treated with bilateral double-J stent insertion, intravenous antibiotic therapy and recovered completely. Read More

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Unknown Extra-Articular Manifestation of Spondyloarthritis: What About Retroperitoneal Fibrosis? A Case Based Literature Review.

Curr Rheumatol Rev 2022 Mar 24. Epub 2022 Mar 24.

Rheumatology Department, Rabta Hospital, Tunis, Tunisia.

Introduction: Retroperitoneal fibrosis (RPF) is a rare disease characterized by fibro-inflammatory tissue proliferation in the retroperitoneum. It results in a chronic inflammatory and fibrosis condition, possibly leading to compression of the retroperitoneal structures, especially to encasement of the ureters and the inferior vena cava. It may have an idiopathic or a secondary origin. Read More

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Thoracobifemoral bypass for infrarenal aortic occlusion caused by retroperitoneal fibrosis.

J Vasc Surg Cases Innov Tech 2022 Jun 26;8(2):132-135. Epub 2022 Jan 26.

Department of Surgery, Advocate Lutheran General Hospital, Park Ridge, Ill.

Retroperitoneal fibrosis (RPF) is an uncommon fibrotic disorder that can cause pain, ureteral obstruction, deep venous thrombosis, hydrocele, and, rarely, aortic occlusion. Herein is described a 65-year-old man with aortic occlusion from idiopathic RPF who was treated with axillobifemoral bypass grafting, which failed in the intermediate term. On representation with critical claudication, he underwent thoracobifemoral bypass grafting via a lateral retroperitoneal tunnel created through a midline, infraumbilical counterincision. Read More

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Pericardial Effusion in Erdheim-Chester Disease: A Case Report and a Mini Literature Review.

Cureus 2022 Feb 8;14(2):e22010. Epub 2022 Feb 8.

Medicine, Sultan Qaboos University Hospital, Muscat, OMN.

A 68-year-old man diagnosed with Erdheim-Chester disease presented to the emergency department with shortness of breath of one-day duration. Upon presentation, the patient was dyspnoeic and hypoxemic. The initial laboratory workup showed raised inflammation markers, and a chest x-ray showed the presence of bilateral lung infiltrates; therefore, he was managed for community-acquired pneumonia with antimicrobial and other supportive measures. Read More

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February 2022

Spontaneous ureteric rupture due to high pressure chronic retention.

JRSM Open 2022 Mar 9;13(3):20542704221077556. Epub 2022 Mar 9.

Department of Urology, Princess Royal University Hospital, King's College Hospital NHS Foundation Trust, Farnborough Common, Orpington BR6 8ND, UK.

Spontaneous ureteric rupture is a rare phenomenon which can be traumatic or non-traumatic that may arise from ureteric obstruction, trauma, mucosal inflammation from urolithiasis, connective tissue disease or retroperitoneal fibrosis. High pressure chronic retention is characterised by noctural enuresis, a tense palpable bladder, hypertension, progressive renal impairment, bilateral hydronephrosis and hydroureter on imaging. Obstructive urological symptoms are typically absent in uncomplicated cases. Read More

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Deep Pelvic Side Wall Anatomy: A Case of Laparoscopic Management of Vaginal Vault Fistula to the Presacral Area.

J Minim Invasive Gynecol 2022 05 2;29(5):583. Epub 2022 Mar 2.

From the Departments of Obstetrics and Gynecology (Dr. Namazi), Minimally Invasive Gynecology (Drs. Gupta and Einarsson), Brigham and Women's Hospital, Boston, Massachusetts.

Study Objective: Video presentation showing retroperitoneal dissection and deep pelvic side wall anatomy [1-3].

Design: Case presentation with showing anatomic structures in detail.

Setting: Tertiary academic teaching hospital. Read More

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Adolescent IgG4-related retroperitoneal fibrosis with left lower extremity edema as the first symptom: A case report.

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2021 Dec;46(12):1437-1441

Department of Urology, Second Xiangya Hospital, Central South University, Changsha 410011, China.

IgG4-related retroperitoneal fibrosis is a type of IgG4-related diseases. The etiology is still unclear. It is often classified as idiopathic retroperitoneal fibrosis, but the pathological process and clinical results between them are different. Read More

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December 2021

Performance characteristics of F-fluciclovine positron emission tomography/computed tomography prior to retroperitoneal lymph node dissection.

Can Urol Assoc J 2022 Mar;16(3):E167-E172

Department of Urology, UT Southwestern Medical Center, Dallas, TX, United States.

Introduction: We aimed to determine whether anti-1-amino-3-F-fluorocyclobutane-1-carboxylic acid (F-fluciclovine) positron emission tomography/computed tomography (PET/CT) can accurately detect residual non-seminomatous germ cell tumor (NSGCT) prior to retroperitoneal lymph node dissection (RPLND). There is no reliable way to differentiate between fibrosis/necrosis, teratoma, and viable germ cell tumor in patients receiving post-chemotherapy RPLND. Functional imaging, including F-fludeoxyglucose (18F-FDG) PET/CT, has been disappointing. Read More

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A case report. Rediscovering tuberculostatics drugs: skin rash and pyrazinamide.

Rev Esp Quimioter 2022 Mar 1. Epub 2022 Mar 1.

Silvia Calpena Martínez, Infectious Diseases Department, Fundación Jiménez Díaz, Universidad Autónoma de Madrid. Av/ Reyes Católicos nº2, 28040, Madrid. Spain.

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Nationwide epidemiological survey of immunoglobulin G4-related disease with malignancy in Japan.

J Gastroenterol Hepatol 2022 Feb 28. Epub 2022 Feb 28.

The Third Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kansai Medical University, Osaka, Japan.

Background And Aim: To clarify the clinicoepidemiological characteristics of immunoglobulin G4 (IgG4)-related disease (IgG4-RD) with malignancy, a nationwide epidemiological survey was conducted.

Methods: Immunoglobulin G4-related disease patients with malignancy who had visited selected hospitals in Japan were surveyed. The study consisted of two stages: the number of IgG4-RD patients with malignancy was estimated by the first questionnaire and their clinicoepidemiological characteristics were assessed by the second questionnaire. Read More

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February 2022

Incidence, prevalence and mortality of chronic periaortitis: a population-based study.

Clin Exp Rheumatol 2022 May 1;40(4):751-757. Epub 2022 Feb 1.

Department of Medicine, Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.

Objectives: To evaluate the epidemiology, presentation and outcomes of patients with chronic periaortitis from 1998 through 2018.

Methods: An inception cohort of patients with incident chronic periaortitis from January 1, 1998 through December 31, 2018, in Olmsted County, Minnesota was identified based on comprehensive individual medical record review utilising the Rochester Epidemiology Project medical record linkage system. Inclusion required radiographic and/or histologic confirmation of periarterial soft tissue thickening around at least part of the infra-renal abdominal aorta or the common iliac arteries. Read More

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Intracoronary IgG4-related disease as an unusual cause of sudden cardiac arrest: a case series.

Eur Heart J Case Rep 2022 Feb 3;6(2):ytac050. Epub 2022 Feb 3.

Department of Cardiology, Baker Heart and Diabetes Institute, 75 Commercial Road, Prahran, VIC 3181, Australia.

Background: IgG4-related disease (IgG4-RD) is a fibro-inflammatory condition classically causing retroperitoneal fibrosis, aortitis, thyroiditis, or pancreatitis. Diagnosis includes the presence of lymphoplasmacytic infiltrate (with >40% ratio IgG4+:IgG plasma cells) and fibrosis. Cardiac involvement may include aortic, pericardial, or coronary disease. Read More

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February 2022