5,788 results match your criteria Retinal Vein Occlusion


Re: Understanding quality of life impact in people with retinal vein occlusion: a qualitative inquiry.

Clin Exp Optom 2019 Apr 24. Epub 2019 Apr 24.

School of Medicine, Dentistry and Biomedical Science, Queen's University of Belfast, Belfast, UK.

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http://dx.doi.org/10.1111/cxo.12906DOI Listing

Response to Re: Understanding quality of life impact in people with retinal vein occlusion: a qualitative inquiry.

Clin Exp Optom 2019 Apr 24. Epub 2019 Apr 24.

Optometry and Vision Science, Flinders University, Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1111/cxo.12911DOI Listing

Multimodal OCT Reflectivity Analysis of the Cystoid Spaces in Cystoid Macular Edema.

Biomed Res Int 2019 20;2019:7835372. Epub 2019 Mar 20.

Eye Clinic, University of Cagliari, Cagliari, Italy.

Purpose: To compare and evaluate images of macular cysts with different degrees of reflectivity (from gray to black signal) as observed in B scan spectral domain OCT (SDOCT) and EnFace OCT with decorrelation signal obtained with OCT-angiography (OCTA) in eyes with cystoid macular edema (CME) secondary to diabetic retinopathy (DR) and retinal vein occlusion (RVO).

Methods: Images from 3033 patients affected by CME secondary to diabetes or RVO examined OCTA (Optovue XR Avanti, Optovue, USA) at the University Eye Clinic of Créteil, Hôpital Intercommunal, France, and at the University Eye Clinic of Cagliari, "San Giovanni di Dio" Hospital, Italy, were retrospectively examined. The deep capillary plexus OCTA images and the corresponding EnFace OCT images, both acquired with the same automatic segmentation, had been overlapped to compose RGB color images as red and green channels, respectively, using ImageJ software (National Institutes of Health, Bethesda, MD). Read More

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http://dx.doi.org/10.1155/2019/7835372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446091PMC

Treat and extend regimen with aflibercept for chronic central retinal vein occlusions: 2 year results of the NEWTON study.

Int J Retina Vitreous 2019 15;5:10. Epub 2019 Apr 15.

1Northern California Retina Vitreous Associates, 2485 Hospital Drive, Suite #200, Mountain View, CA 94040 USA.

Background: To determine whether aflibercept (Eylea; Regeneron Pharmaceuticals, Inc., Tarrytown, NY) could continue to extend the macular edema free interval in patients on a treat and extend (TAE) with non-ischemic central retinal vein occlusions (CRVOs) previously treated with ranibizumab (Lucentis; Genentech, Inc., South San Francisco, CA) or bevacizumab (Avastin; Genentech, Inc. Read More

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http://dx.doi.org/10.1186/s40942-019-0159-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463635PMC

Intravitreal dexamethasone implant for central retinal vein occlusion without macular edema.

BMC Ophthalmol 2019 Apr 17;19(1):92. Epub 2019 Apr 17.

Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211, Eonjuro, Gangnam-gu, Seoul, 06273, South Korea.

Background: To evaluate the efficacy of an intravitreal dexamethasone (IVD) implant (Ozurdex®) for the treatment of central retinal vein occlusion (CRVO) without macular edema (ME).

Methods: A retrospective cohort study was designed, and 20 eyes of 20 patients diagnosed with non-ischemic CRVO without ME were included. A total of 10 CRVO eyes were observed without treatment, and another 10 CRVO eyes received a single IVD injection at baseline. Read More

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https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12886-019-1097-yDOI Listing
April 2019
2 Reads

Branch Retinal Vein Occlusion in Ipsilateral Harlequin Syndrome.

Klin Monbl Augenheilkd 2019 Apr 18;236(4):587-589. Epub 2019 Apr 18.

Retinology Unit, Pallas Klinik Olten, Olten, Switzerland.

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http://dx.doi.org/10.1055/a-0861-9643DOI Listing

Retinal oximetry: Metabolic imaging for diseases of the retina and brain.

Prog Retin Eye Res 2019 Apr 15. Epub 2019 Apr 15.

University of Iceland, Reykjavik, Iceland.

Retinal oximetry imaging of retinal blood vessels measures oxygen saturation of hemoglobin. The imaging technology is non-invasive and reproducible with remarkably low variability on test-retest studies and in healthy cohorts. Pathophysiological principles and novel biomarkers in several retinal diseases have been discovered, as well as possible applications for systemic and brain disease. Read More

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http://dx.doi.org/10.1016/j.preteyeres.2019.04.001DOI Listing
April 2019
3 Reads

Intravitreal Anti-Vascular Endothelial Growth Factor Injections for Macular Edema Associated With Central Retinal Vein Occlusion in Patients Age 40 Years or Younger.

Ophthalmic Surg Lasers Imaging Retina 2019 Apr;50(4):e96-e104

Background And Objective: To determine the efficacy of anti-vascular endothelial growth factor (VEGF) therapy for macular edema due to central retinal vein occlusion (CRVO) in younger adults.

Patients And Methods: The outcomes of CRVO patients age 40 years or younger with baseline logarithm of the minimum angle of resolution (logMAR) visual acuity (VA) between 1.30 (20/400 Snellen equivalent) and 0. Read More

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http://dx.doi.org/10.3928/23258160-20190401-13DOI Listing

Five-year outcomes of retinal vein occlusion treated with vascular endothelial growth factor inhibitors.

BMJ Open Ophthalmol 2019 29;4(1):e000249. Epub 2019 Mar 29.

Sydney Institute of Vision Science, Sydney, New South Wales, Australia.

Purpose: Report 5-year outcomes of patients receiving anti-vascular endothelial growth factor (VEGF) for the treatment of macular oedema secondary to retinal vein occlusion (RVO.

Methods: Retrospective review of eyes with RVO which initiated anti-VEGF treatment. Data including age, gender, visual acuity (VA) and injection numbers were obtained from medical records. Read More

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http://dx.doi.org/10.1136/bmjophth-2018-000249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440600PMC

Restoring retinal neurovascular health via substance P.

Exp Cell Res 2019 Apr 14. Epub 2019 Apr 14.

Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, UK; National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK. Electronic address:

Regulation of vascular permeability plays a major role in the pathophysiology of visually threatening conditions such as retinal vein occlusion and diabetic retinopathy. Principally, several factors such as vascular endothelial growth factor (VEGF), are up-regulated or induced in response to hypoxia thus adversely affecting the blood-retinal barrier (BRB), resulting in retinal edema and neovascularisation. Furthermore, current evidence supports a dysregulation of the inner retinal neural-vascular integrity as a critical factor driving retinal ganglion cell (RGC) death and visual loss. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00144827193015
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http://dx.doi.org/10.1016/j.yexcr.2019.04.008DOI Listing
April 2019
1 Read

An overview of optical coherence tomography angiography and the posterior pole.

Ther Adv Ophthalmol 2019 Jan-Dec;11:2515841419840249. Epub 2019 Apr 3.

Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Optical coherence tomography angiography is a relatively new, noninvasive technology that has revolutionized imaging of the retinal and choroidal microvasculature. This technology is based on the detection of movement or changes that represent moving red cells in sequential optical coherence tomography scans. As with other established imaging technologies, it has unique benefits as well as certain disadvantages, which include a limited field of view and vulnerability to imaging artifacts. Read More

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http://dx.doi.org/10.1177/2515841419840249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448101PMC

Macular function following intravitreal ranibizumab for macular edema associated with branch retinal vein occlusion.

Doc Ophthalmol 2019 Apr 12. Epub 2019 Apr 12.

Department of Ophthalmology, Dokkyo Medical University Saitama Medical Center, 2-1-50 Minamikoshiagya, Koshigaya, 343-8555, Saitama, Japan.

Purpose: To determine the physiology of the macula by the focal macular electroretinograms (fmERGs) in patients with branch retinal vein occlusion with macular edema (BRVOME) treated by intravitreal injections of ranibizumab (IVR).

Methods: We studied 17 eyes of 17 patients with BRVOME. The contralateral unaffected eyes served as controls. Read More

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http://dx.doi.org/10.1007/s10633-019-09696-5DOI Listing

Mean platelet volume and central retinal vein occlusion in hypertensive patients.

Can J Ophthalmol 2019 Apr 22;54(2):275-279. Epub 2018 Jun 22.

Department of Vitreo-Retina Surgery, Grant Medical College and Sir J. J. Group of Hospitals, Mumbai, India.

Objective: To study the relationship between mean platelet volume (MPV) and central retinal vein occlusion (CRVO) in hypertensive patients.

Design: Hospital-based, retrospective, case control design.

Participants: The sample group consisted of 100 patients with a known history of hypertension and who are diagnosed with CRVO. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00084182183019
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http://dx.doi.org/10.1016/j.jcjo.2018.04.014DOI Listing
April 2019
6 Reads
1.299 Impact Factor

A novel strategy for quantification of panoramic en face optical coherence tomography angiography scan field.

Graefes Arch Clin Exp Ophthalmol 2019 Apr 10. Epub 2019 Apr 10.

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Purpose: To compare the retinal area measured on a panoramic en face optical coherence tomography angiography (OCTA) image with that on an ultra-widefield fluorescein angiography (UWF FA) image.

Methods: Sixteen eyes (11 with branch retinal vein occlusion, 2 with central retinal vein occlusion, 1 with branch retinal artery occlusion, and 2 with hypertensive retinopathy) were included in this study. A panoramic en face OCTA image was created from five single non-panoramic en face OCTA 12 × 12-mm images. Read More

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http://dx.doi.org/10.1007/s00417-019-04310-5DOI Listing

Genetic correlation between Prothrombin G20210A polymorphism and retinal vein occlusion risk.

Braz J Med Biol Res 2019 Apr 8;52(4):e8217. Epub 2019 Apr 8.

Department of Refraction and Cornea, Tianjin Medical University Eye Hospital, School of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, China.

The aim of this study was to perform an updated meta-analysis to quantitatively investigate the association between G20210A polymorphism of Prothrombin gene and the risk of retinal vein occlusion (RVO), based on the available publications with inconsistent results. We utilized the Stata software to perform the heterogeneity test, association test, Begg's and Egger's tests, and sensitivity analysis. We searched three on-line databases (PubMed, Embase, and WOS) and obtained a total of 422 articles. Read More

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http://dx.doi.org/10.1590/1414-431X20198217DOI Listing

Real-Life Evidence for Using a Treat-and-Extend Injection Regime for Patients with Central Retinal Vein Occlusion.

Ophthalmol Ther 2019 Apr 10. Epub 2019 Apr 10.

Medical Retina Service, Moorfields Eye Hospital, London, UK.

Introduction: To report the 52-week treatment outcomes with intravitreal injections of aflibercept using a treat-and-extend regimen for treating macular edema secondary to central retinal vein occlusion (CRVO).

Methods: A retrospective analysis of patients newly diagnosed with CRVO was performed. Patients receiving aflibercept between 1 December 2016 and 31 March 2017 were included in the analysis. Read More

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http://dx.doi.org/10.1007/s40123-019-0184-8DOI Listing

Assessment of Monocyte/HDL Ratio in Branch Retinal Vein Occlusion.

Ocul Immunol Inflamm 2019 Apr 9:1-5. Epub 2019 Apr 9.

a Meram Faculty of Medicine, Department of Ophthalmology , Necmettin Erbakan University , Konya , Türkiye.

Purpose: The purpose of this article was to evaluate monocyte count and high-density lipoprotein (HDL) cholesterol levels and their ratio (monocyte/HDL ratio [MHR]) in patients with branch retinal vein occlusion (BRVO).

Materials And Methods: A total of 50 participants were included in the study. Participants were divided into two groups: Twenty-five patients diagnosed with BRVO and 25 participants as the control group. Read More

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https://www.tandfonline.com/doi/full/10.1080/09273948.2019.1
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http://dx.doi.org/10.1080/09273948.2019.1569244DOI Listing
April 2019
9 Reads

Retinal vein occlusion is associated with low blood high-density lipoprotein cholesterol: a nationwide cohort study.

Am J Ophthalmol 2019 Apr 5. Epub 2019 Apr 5.

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Purpose: To investigate association between the development of retinal vein occlusion (RVO) and blood high-density lipoprotein cholesterol (HDL-C).

Design: A retrospective, nationwide, population-based cohort study.

Methods Setting: Republic of Korea STUDY POPULATION: This study included 23,149,403 people aged 20 years or older who underwent the Korean National Health Screening Program examination between January 2009 and December 2012. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029394193015
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http://dx.doi.org/10.1016/j.ajo.2019.04.001DOI Listing
April 2019
8 Reads

The V617F mutation in retinal vein or artery occlusion.

EXCLI J 2019 4;18:127-128. Epub 2019 Mar 4.

Cancer Molecular Diagnostics, St. James's Hospital, Dublin, Ireland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449673PMC

Efficacy and safety of intravitreal drug injections using a short 34-gauge needle.

Jpn J Ophthalmol 2019 Apr 6. Epub 2019 Apr 6.

Department of Ophthalmology, Aichi Medical University, 1-1 Yazako-Karimata, Nagakute, 480-1195, Aichi, Japan.

Purpose: To evaluate the efficacy and safety of intravitreal drug injections using a short 34-gauge needle.

Study Design: Retrospective study.

Methods: This study included patients with age-related macular degeneration, diabetic macular edema, or macular edema associated with retinal vein occlusion. Read More

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http://dx.doi.org/10.1007/s10384-019-00663-wDOI Listing
April 2019
1 Read

Loss of Peak Vision in Retinal Vein Occlusion Patients Treated for Macular Edema.

Am J Ophthalmol 2019 Apr 4. Epub 2019 Apr 4.

The Wilmer Eye Institute, Johns Hopkins University, Baltimore MD. Electronic address:

Purpose: To evaluate long term visual and anatomic outcomes in patients with retinal vein occlusion (RVO) treated with anti-vascular endothelial growth factor (VEGF) agents DESIGN: Prospective, interventional case series PARTICIPANTS: Patients with central RVO (CRVO) or branch RVO (BRVO) METHODS: Number of anti-VEGF injections and improvement from baseline best-corrected visual acuity (BCVA) and central subfield thickness (CST) were prospectively recorded in 40 eyes of 39 CRVO patients and 50 eyes of 47 BRVO patients.

Results: Mean follow up was 58 months for BRVO and 78 months for CRVO. Within 6 months of last follow up, 58% of BRVO patients and 75% of CRVO patients required anti-VEGF injections to control edema. Read More

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http://dx.doi.org/10.1016/j.ajo.2019.03.029DOI Listing
April 2019
3.871 Impact Factor

Cystoid macular oedema following cataract surgery: A review.

Clin Exp Ophthalmol 2019 Apr;47(3):346-356

Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

Pseudophakic cystoid macular oedema (PCMO) remains a significant cause of compromised postoperative vision in contemporary cataract surgery. Well-established risk factors include intraoperative complications such as posterior capsule rupture and preoperative factors including: diabetes mellitus, uveitis, retinal vein occlusion, epiretinal membrane. The role of topical glaucoma medications in PCMO continues to be debated. Read More

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http://dx.doi.org/10.1111/ceo.13513DOI Listing
April 2019
2 Reads

Activated Protein C for Ischemic Central Retinal Vein Occlusion: One-Year Results.

Ophthalmol Retina 2019 Jan 25;3(1):93-94. Epub 2018 Jul 25.

Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.

Intravitreally administered activated protein C in 10 eyes with ischemic central retinal vein occlusion significantly improved macular edema; in 5 eyes, the reperfusion of the retinal nonperfused areas exceeded 50% of baseline. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24686530183041
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http://dx.doi.org/10.1016/j.oret.2018.07.012DOI Listing
January 2019
8 Reads

Nd:YAG laser therapy for non-resolving premacular subhyaloid hemorrhage in Saudi patients.

Saudi J Ophthalmol 2019 Jan-Mar;33(1):61-65. Epub 2018 Dec 8.

Ophthalmology Department, Menoufia University, Shebin El-Kom, Egypt.

Purpose: To report anatomical and visual outcomes of Nd:YAG laser posterior hyaloidotomy (NYPH) in Saudi patients affected by Premacular subhyaloid haemorrhage (PMSHH).

Methods: 8 eyes from 8 patients (7 males and one female) were treated with NYPH when no spontaneous resolution of PMSHH was noticed. The cause of PMSHH was proliferative diabetic retinopathy (PDR) in 3 cases, Central retinal vein occlusion (CRVO) in 2 cases, Valsalva retinopathy in 2 cases, and laser pointer injury in one case. Read More

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http://dx.doi.org/10.1016/j.sjopt.2018.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424697PMC
December 2018
1 Read

Vision Impairment in CKD Patients: Epidemiology, Mechanisms, Differential Diagnoses, and Prevention.

Am J Kidney Dis 2019 Mar 28. Epub 2019 Mar 28.

Singapore Eye Research Institute, Singapore National Eye Centre; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore; Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School. Electronic address:

Eyes and kidneys have numerous structural, developmental, physiologic, and pathogenic pathways in common, suggesting that many kidney and eye diseases may be interlinked. Studies suggest that the prevalence of eye diseases and vision impairment are higher among persons with end-stage kidney disease and earlier stages of chronic kidney disease (CKD) than in those without. Ocular morbidity in persons with CKD and end-stage kidney disease may be due to the following risk factors: (1) underlying conditions and risk factors for CKD such as diabetes or hypertension, (2) metabolic disorders associated with CKD, (3) uremia and anemia, and (4) CKD treatment. Read More

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http://dx.doi.org/10.1053/j.ajkd.2018.12.047DOI Listing
March 2019
5 Reads
5.900 Impact Factor

Re: Berry et al: Association of Disorganization of Retinal Inner Layers with Ischemic Index and Visual Acuity in Central Retinal Vein Occlusion (Ophthalmol Retina. 2018;2:1125-1132).

Ophthalmol Retina 2019 Jan 26;3(1):e1. Epub 2018 Sep 26.

Department of Ophthalmology, University of Medicine, Cluj-Napoca, Romania. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24686530183043
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http://dx.doi.org/10.1016/j.oret.2018.09.014DOI Listing
January 2019
4 Reads

Disorganization of Retinal Inner Layers and Ellipsoid Zone Disruption Predict Visual Outcomes in Central Retinal Vein Occlusion.

Ophthalmol Retina 2019 Jan 19;3(1):83-92. Epub 2018 Oct 19.

Department of Ophthalmology, McGill University, Montreal, Canada; Montreal Retina Institute, Montreal, Canada. Electronic address:

Purpose: To assess the associations and predictive value of spectral-domain (SD) OCT inner and outer retinal structural parameters and visual acuity (VA) outcomes in macular edema (ME) secondary to central retinal vein occlusion (CRVO).

Design: Retrospective, longitudinal cohort study.

Participants: Eighty-four patients with ME secondary to CRVO receiving pro re nata anti-vascular endothelial growth factor (VEGF) therapy at 3 tertiary-level retina referral centers. Read More

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http://dx.doi.org/10.1016/j.oret.2018.07.008DOI Listing
January 2019
6 Reads

A real-world study of effectiveness of intravitreal bevacizumab and ranibizumab injection for treating retinal diseases in Thailand.

BMC Ophthalmol 2019 Mar 29;19(1):82. Epub 2019 Mar 29.

Health Intervention and Technology Assessment Program (HITAP), Ministry of Public Health, Nonthaburi, Thailand.

Background: To evaluate the effectiveness of intravitreal bevacizumab (IVB) and intravitreal ranibizumab (IVR) in actual practice for treating patients with retinal diseases in Thailand.

Methods: A prospective, multi-centre, observational study was conducted among eight hospitals in their ophthalmology outpatient departments. Participants consisted of patients who had previously not received any IVB or IVR treatment between 2013 and 2014. Read More

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http://dx.doi.org/10.1186/s12886-019-1086-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439979PMC
March 2019
2 Reads

Sectoral changes of the peripapillary choroidal thickness in patients with unilateral branch retinal vein occlusion.

Int J Ophthalmol 2019 18;12(3):472-479. Epub 2019 Mar 18.

Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.

Aim: To investigate sectoral changes in the mean peripapillary choroidal thickness (PCT) in patients with unilateral branch retinal vein occlusion (BRVO).

Methods: This retrospective, interventional study included 41 patients with acute, unilateral BRVO without macular edema. All patients completed at least a 6-month follow-up period. Read More

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http://dx.doi.org/10.18240/ijo.2019.03.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423387PMC
March 2019
1 Read
0.500 Impact Factor

Management of the open angle glaucoma in patients with central/hemicentral retinal vein occlusions.

Int J Ophthalmol 2019 18;12(3):436-441. Epub 2019 Mar 18.

Department of Ophthalmology, University of Medicine, Cluj-Napoca 400014, Romania.

Aim: To prospectively assess the cumulative prevalence and management of open angle glaucoma (OAG), including primary open angle glaucoma (POAG) with high and normal-pressure, as well as pseudoexfoliative glaucoma (PEXG), in patients with central/hemicentral retinal vein occlusions (RVOs) over a 3-year follow-up period.

Methods: The study encompassed 57 patients with unilateral acute central/hemicentral RVOs. A complete ophthalmic examination of both eyes was undertaken for all patients. Read More

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http://dx.doi.org/10.18240/ijo.2019.03.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423395PMC

Therapeutic Effect of Traditional Chinese Medicine on a Rat Model of Branch Retinal Vein Occlusion.

J Ophthalmol 2019 18;2019:9521379. Epub 2019 Feb 18.

Institute of Neurobiology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China.

Branch retinal vein occlusion (BRVO) is a common retinal vascular disorder leading to visual impairment. Currently, the general strategies for BRVO are symptomatic therapies. Cardiovascular aspects are essential risk factors for BRVO. Read More

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http://dx.doi.org/10.1155/2019/9521379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398022PMC
February 2019

Misery perfusion, diffusive oxygen shunting and interarterial watershed infarction underlie oxygenation-based hypoperfusion maculopathy.

Authors:
David McLeod

Am J Ophthalmol 2019 Mar 21. Epub 2019 Mar 21.

Academic Department of Ophthalmology, Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Oxford Road, Manchester M13 9WL, UK; and Centre for Ophthalmology and Vision Research, Institute of Human Development, University of Manchester, Manchester, United Kingdom. Electronic address:

Purpose: To describe and explain the entire range of ischemic macular damage that follows panretinal hypoperfusion from central retinal artery or vein occlusion.

Design: Perspective article.

Methods: Correlation of the fundoscopic, fluorescein angiographic, oximetric and optical coherence tomographic (OCT) features developing within the posterior inner retina following incremental reductions in arterio-venous perfusion pressure across the retinal circulation. Read More

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http://dx.doi.org/10.1016/j.ajo.2019.03.015DOI Listing
March 2019
1 Read

Evaluation of retinal nonperfusion in branch retinal vein occlusion using wide-field optical coherence tomography angiography.

Acta Ophthalmol 2019 Mar 22. Epub 2019 Mar 22.

Department of Ophthalmology, Osaka University Graduate School of Medicine, Yamadaoka, Japan.

Purpose: To characterize wide-field optical coherence tomography angiography (OCTA) features of retinal nonperfusion in eyes with branch retinal vein occlusion (BRVO).

Methods: Automated scanning of five 12 × 12-mm areas of swept-source OCTA and wide-field fluorescein angiography (FA) images was performed in a consecutive case series of 27 eyes in 27 patients with BRVO in this institutional cross-sectional study. The correlation between the areas of retinal nonperfusion detected by both examinations was assessed. Read More

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http://dx.doi.org/10.1111/aos.14087DOI Listing

Outcome After Exchange Transfusion for Central Retinal Vein Occlusion Associated With Extensive Capillary and Arteriolar Nonperfusion in a Patient With Hemoglobin SS Disease.

JAMA Ophthalmol 2019 Mar 21. Epub 2019 Mar 21.

Retina Division, Wilmer Eye Institute, Johns Hopkins University School of Medicine and Hospital, Baltimore, Maryland.

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http://archopht.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaophthalmol.2019.0165DOI Listing
March 2019
7 Reads

Loss to Follow-Up in Patients With Retinal Vein Occlusion Undergoing Intravitreal Anti-VEGF Injections.

Ophthalmic Surg Lasers Imaging Retina 2019 Mar;50(3):159-166

Background And Objective: To identify the proportion of patients with retinal vein occlusion (RVO) with loss to follow-up (LTFU) along with potential risk factors after receiving an intravitreal anti-vascular endothelial growth factor (VEGF) injection.

Patients And Methods: A retrospective review based on billing codes was performed from January 1, 2012, to January 1, 2017. LTFU was defined as no office visit within 12 months following an intravitreal injection. Read More

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http://dx.doi.org/10.3928/23258160-20190301-05DOI Listing
March 2019
3 Reads

Romanian ophthalmologists in the renowned ophthalmic journals worldwide.

Rom J Ophthalmol 2018 Oct-Dec;62(4):260-269

OcuCenter Ophthalmological Clinic, Cluj-Napoca, Romania.

The authors are discussing over 80 articles that they have published in the last 5 years in the renowned ophthalmic journals worldwide, which have approached, for the first time in the ophthalmic literature, the following 4 topics: the acute central/ hemicentral retinal vein occlusion, the therapeutic interventions in the fellow eye of patients with unilateral malignant glaucoma, the persistent diabetic macular edema, and the current researches in patients with neovascular age-related macular degeneration. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421486PMC
April 2019
1 Read

Chronic spontaneous coronary artery dissection in association with antiphospholipid syndrome presenting as stable angina.

BMJ Case Rep 2019 Mar 14;12(3). Epub 2019 Mar 14.

Department of Cardiology, University Hospital Limerick, Limerick, Ireland.

A 52-year-old man presented to our cardiology service for an elective diagnostic coronary angiogram for risk stratification in the context of stable angina. He was diagnosed with antiphospholipid syndrome 2 years prior and had three known thrombotic episodes in the form of a stroke, retinal artery occlusion and deep vein thrombosis. Our initial differential was atherosclerotic coronary artery disease, however, coronary angiography demonstrated a dominant right coronary artery with a long segment of chronic spontaneous dissection distally but with thrombolysis in myocardial infarction III flow. Read More

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http://dx.doi.org/10.1136/bcr-2018-227674DOI Listing
March 2019
1 Read

Predictors of Neovascular Glaucoma in Central Retinal Vein Occlusion.

Am J Ophthalmol 2019 Mar 9. Epub 2019 Mar 9.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL.

Purpose: To determine the risk factors for development of neovascular glaucoma (NVG) in patients after an acute central retinal vein occlusion (CRVO).

Design: Retrospective cohort study METHODS: Review of medical records of 646 patients with a diagnosis of CRVO between 2013 to 2017 at the Bascom Palmer Eye Institute.

Inclusion Criteria: 1) CRVO onset to presentation <90 days; 2) Absence of anterior segment neovascularization on presentation; 3) No intravitreal anti-VEGF injection before presentation. Read More

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http://dx.doi.org/10.1016/j.ajo.2019.02.038DOI Listing

Effect of intravitreal aflibercept on corneal endothelial cells: a 6-month follow-up study.

Clin Ophthalmol 2019 15;13:373-381. Epub 2019 Feb 15.

Department of Ophthalmology, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan,

Purpose: To determine the effect of intravitreal aflibercept injection on the corneal endothelium in patients with diabetic or cystoid macular edema caused by retinal vein occlusion.

Material And Methods: Forty-six eyes of 44 consecutive patients (27 men, 17 women; age range: 55-88 years) were evaluated. All participants initially received a single intravitreal injection of aflibercept (2 mg in 0. Read More

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http://dx.doi.org/10.2147/OPTH.S177506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387600PMC
February 2019

[Anatomo-functional study in branch retinal vein occlusion using Swept Source Optical Coherence Tomography Angiography].

J Fr Ophtalmol 2019 Mar 8;42(3):255-261. Epub 2019 Mar 8.

Hôpital Habib Thameur, 3, rue A.Ben Ayed, 1089 Tunis, Tunisie; Faculté de médecine de Tunis, Université Tunis EL MANAR, Tunisie.

Introduction: The purpose of our study was to describe the microvascular abnormalities on OCT-angiography in eyes with branch retinal vein occlusion (BRVO), to measure the surface of the foveal avascular zone (FAZ) and the capillary density, and to establish anatomic-functional correlations.

Methods: We conducted an observational prospective study in the ophthalmology department of Habib Thameur Hospital in Tunis, which included 17 eyes of patients with unilateral BRVO. We studied the microvascular abnormalities and areas of capillary non-perfusion in the deep and superficial capillary plexuses (DCP, SCP). Read More

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http://dx.doi.org/10.1016/j.jfo.2018.09.010DOI Listing

Ocular manifestations of pulmonary hypertension.

Surv Ophthalmol 2019 Mar 5. Epub 2019 Mar 5.

Department and Clinic of Ophthalmology, Wroclaw Medical University, Poland, ul. Borowska 213, PL-50-556 Wrocław, Poland.

Pulmonary hypertension (PH), if left untreated, may result in increasing cardiac back pressures and lead to right heart failure and death. An increase in venous pressure in pulmonary hypertension influences other organs. The ocular complications occur as a result of elevated venous pressure in the superior vena cava and in the ophthalmic veins that cause dilation of the ocular veins, resulting in congestion of the choroid and leading to complications such as ciliary detachment, central retinal vein occlusion, acute serous retinal detachment, macular edema, retinal neovascularization, choroidal effusions, chemosis, angle-closure glaucoma, transient myopia, and proptosis. Read More

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http://dx.doi.org/10.1016/j.survophthal.2019.02.009DOI Listing
March 2019
1 Read

[Hypertension and Framingham general vascular risk score in retinal vein occlusion].

Hipertens Riesgo Vasc 2019 Mar 2. Epub 2019 Mar 2.

Servicio de Medicina Interna, Hospital Universitario Marqués de Valdecilla, Santander, España.

Objectives: To determine the prevalence of arterial hypertension (AHT), systolic blood pressure (SBP), the diastolic blood pressure (DPB), and the Framingham vascular risk score (FRS), in subjects with retinal vein occlusion (RVO), as well as in a control group.

Patients And Method: A prospective, cross-sectional case and control study was conducted on all patients with a diagnosis of RVO referred to the General Medicine Clinic, and comparing them with a control group. An analysis was performed on the clinical and laboratory variables. Read More

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http://dx.doi.org/10.1016/j.hipert.2018.12.004DOI Listing
March 2019
3 Reads

ASSOCIATION OF RETINAL VEIN OCCLUSION WITH CARDIOVASCULAR EVENTS AND MORTALITY: A Systematic Review and Meta-analysis.

Retina 2019 Feb 28. Epub 2019 Feb 28.

Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York.

Purpose: Previous studies examining the association of retinal vein occlusion (RVO) and cardiovascular events have been inconsistent and have mostly focused on stroke and myocardial infarction. The goal of this study is to use meta-analysis to examine the available evidence examining the association of RVO with incident cardiovascular events and mortality.

Methods: Systematic review and meta-analysis of all longitudinal cohort studies published in PubMed, Embase, and the Cochrane Library from inception to April 7, 2018, that evaluated the association of baseline RVO and incident cardiovascular events and/or mortality, that provided multivariate-adjusted risk estimates with 95% confidence intervals (95% CIs), and that had average follow-up ≥1 year. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002472DOI Listing
February 2019

Central retinal vein occlusion in a patient with breast carcinoma.

GMS Ophthalmol Cases 2019 12;9:Doc04. Epub 2019 Feb 12.

Arasan Eye Hospital, Erode, India.

Systemic malignancies may have ocular manifestations in the form of metastatic tumors, carcinoma associated retinopathy or central retinal vein occlusion (CRVO). Although CRVO has been mentioned in association with renal, lung, prostatic and ovarian malignancies, the association of CRVO with breast carcinoma is unreported. We report a patient with one such rare association. Read More

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http://dx.doi.org/10.3205/oc000093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381396PMC
February 2019

Aspirin use in central retinal arterial occlusion to prevent ischaemic stroke: a retrospective cohort study in Taiwan.

BMJ Open 2019 Feb 27;9(2):e025455. Epub 2019 Feb 27.

Chang Gung University, College of Medicine, Taoyuan, Taiwan.

Objective: To understand the efficacy of aspirin use for preventing ischaemic stroke after central retinal artery occlusion (CRAO).

Design: The retrospective cohort study was conducted using the National Health Insurance Research Database from 1998 to 2013.

Setting: A population-based study. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-025455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398622PMC
February 2019
3 Reads

Retinal oximetry in branch retinal vein occlusion.

Acta Ophthalmol 2019 Feb 28. Epub 2019 Feb 28.

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Purpose: To measure retinal oxygen saturation (SO ) in eyes with branch retinal vein occlusion (BRVO).

Methods: Retinal oximetry was performed using the Oxymap T1 retinal oximeter in 50 eyes (50 patients) with resolved BRVO. SO was calculated in each major retinal artery and vein in four quadrants. Read More

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http://dx.doi.org/10.1111/aos.14070DOI Listing
February 2019
4 Reads

Dexamethasone intravitreous implant vs bevacizumab for central retinal vein occlusion related macular oedema: A prospective randomized comparison-Response.

Clin Exp Ophthalmol 2019 Feb 28. Epub 2019 Feb 28.

Department of Ophthalmology, Kasr El Aini Hospitals, Cairo University, Cairo, Egypt.

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http://dx.doi.org/10.1111/ceo.13490DOI Listing
February 2019
2 Reads

Optical biometry-based axial length alterations after intravitreal dexamethasone implant.

Arq Bras Oftalmol 2019 Feb 25. Epub 2019 Feb 25.

Trakya University School of Medicine, Department of Ophthalmology, Edirne, Turkey.

Purpose: To investigate changes in axial length after intravitreal dexamethasone implantation in patients with macular edema.

Methods: We performed a prospective comparative study of 46 patients with unilateral macular edema, due to diabetic retinopathy, retinal vein occlusion, and non-infectious uveitis, who underwent dexamethasone implantation. The fellow eyes of the patients were considered the control group. Read More

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http://dx.doi.org/10.5935/0004-2749.20190040DOI Listing
February 2019
5 Reads