2,969 results match your criteria Retinal Detachment Proliferative


Demography, clinical profile and surgical outcomes of paediatric giant retinal tear related retinal detachments.

Eye (Lond) 2021 Jun 11. Epub 2021 Jun 11.

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Objective: To determine the demographic profile, clinical features and surgical outcomes of giant retinal tear (GRT) related retinal detachments (RD) in children.

Methods: In this retrospective study, medical records of children aged 14 years and below, who underwent surgery for RD at our centre in the last 5 years were reviewed. Among these, we selected medical records of children with RDs with GRT, and examined the coloured retinal drawings, ultrawidefield photographs and/or surgical videos. Read More

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Surgical Outcomes of Rhegmatogenous Retinal Detachment with Different Peripheral Vitreous-Shaving Procedures.

Clin Ophthalmol 2021 28;15:2197-2202. Epub 2021 May 28.

Department of Ophthalmology and Visual Sciences, Yamagata University Faculty of Medicine, Yamagata, Japan.

Purpose: To compare the surgical outcomes of vitreous surgery for rhegmatogenous retinal detachment (RRD) after two different peripheral vitreous-shaving techniques are performed.

Methods: We reviewed 269 eyes with RRD that were treated with a 25-gauge vitrectomy by a single surgeon between June 2015 and May 2020. The exclusion criteria for the proposed air tamponade selection were as follows: more than two weeks since RRD onset, giant retinal tears, a history of complications following cataract surgery, high myopia, and proliferative vitreoretinopathy classified as grade C or higher. Read More

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[Minimally invasive vitrectomy for the treatment of severe proliferative diabetic retinopathy].

Zhonghua Yan Ke Za Zhi 2021 Jun;57(6):440-446

Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Tianjin 300384, China.

To report the efficacy and safety of minimally invasive vitrectomy for the treatment of severe proliferative diabetic retinopathy (PDR) and the effect of preoperative retinal photocoagulation on prognosis. Case-series study and cohort study. This study included 48 severe PDR patients (53 eyes). Read More

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[Reasons and risk factors for recurrent retinal detachment after removal of silicon oil in various vitreoretinal diseases].

Ophthalmologe 2021 Jun 4. Epub 2021 Jun 4.

Universitäts-Augenklinik, Universitätsklinikum Gießen und Marburg GmbH, Standort Marburg, Baldingerstrasse, Marburg, 35043, Deutschland.

Background: Pars plana vitrectomy (ppV) combined with silicone oil tamponade is a standard technique in the treatment of complicated retinal detachment. There are still recurrent cases of retinal detachment after silicone oil removal or redetachment with in situ oil tamponade.

Objective: The aim was to identify possible risk factors for retinal redetachment and to use the knowledge for optimizing treatment. Read More

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Corneal Toxicity of Intravitreal Methotrexate Used for the Treatment of Proliferative Vitreoretinopathy in Silicone Oil-Filled Eyes: A Case Series.

Cornea 2021 Jun 1. Epub 2021 Jun 1.

University of California, San Francisco, Department of Ophthalmology, San Francisco, CA; and Zuckerberg San Francisco General Hospital and Trauma Center, Department of Ophthalmology, San Francisco, CA.

Purpose: The purpose of this study was to evaluate the corneal toxicity of intravitreal methotrexate used for the prevention of proliferative vitreoretinopathy (PVR).

Methods: In this retrospective case series, eyes with recurrent retinal detachment secondary to PVR were treated with intravitreal injections of 400 μg methotrexate at an average frequency of every 7 days after vitrectomy with silicone oil tamponade. Corneas were examined for corneal epitheliopathy by slit-lamp biomicroscopy before each injection. Read More

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Antioxidant Status in the Vitreous of Eyes with Rhegmatogenous Retinal Detachment with and without Proliferative Vitreoretinopathy, Macular Hole and Epiretinal Membrane.

Life (Basel) 2021 May 19;11(5). Epub 2021 May 19.

Chair and Department of General and Pediatric Ophthalmology, Medical University of Lublin, 20-059 Lublin, Poland.

(1) Background: The aim of the study was to test the hypothesis that the antioxidant status in the vitreous body of eyes, which had been vitrectomized due to rhegmatogenous retinal detachment (RRD) with or without proliferative vitreoretinopathy (PVR), is higher than in eyes vitrectomized due to other retinal diseases. (2) Methods: four patient groups were analyzed: 22 eyes of patients with RRD without PVR, 27 eyes with RRD and PVR, 22 eyes with macular hole (MH) and 10 eyes with epiretinal membrane (ERM). Spectrophotometric methods were used to determine the total antioxidant status (TAS) values as well as superoxide dismutase (SOD) and glutathione reductase (GR) activities in the vitreous fluid samples. Read More

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From the Hypotheses to Clinical Evidence in Retinal Therapy.

J Ophthalmic Vis Res 2021 Apr-Jun;16(2):287-290. Epub 2021 Apr 29.

Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD.

The off-label, therapeutic use of intravitreal bevacizumab (IVB) in vascular retinal diseases such as diabetic macular edema and proliferative diabetic retinopathy (PDR) has increased significantly due to its ability to reduce retinal neovascularization and slow progression of disease. Here, we will review the literature and investigative developments on the use of IVB as a preoperative adjuvant to vitrectomy in severe PDR, specifically focusing on its ability to reduce intra- and postoperative complications and its risk for progression or development of traction retinal detachment. In particular, this review will highlight the natural progression of evidence from case series and observations to prospective, randomized clinical trials. Read More

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A Case of Presumed Dyskeratosis Congenita Causing Severe Retinal Vascular Occlusion.

Case Rep Ophthalmol 2021 May-Aug;12(2):344-349. Epub 2021 May 7.

Department of Ophthalmology, Osaka Medical College, Takatsuki-City, Japan.

Dyskeratosis congenita (DKC) is a rare, multisystem, bone marrow failure disease characterized by abnormalities such as in the skin, mucosa, nervous system, and lungs. Here we report a rare case of presumed DKC causing total retinal detachment in the right eye and severe peripheral retinal vascular occlusion in the left eye. A 3-year-old boy was presented with vitreous hemorrhage and total retinal detachment in the right eye and was scheduled to undergo vitreous surgery in the right eye and detailed ophthalmologic examination of the left eye under general anesthesia. Read More

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Posterior Segment Injuries in Operation Iraqi Freedom and Operation Enduring Freedom: 2001-2011.

Retina 2021 May 27. Epub 2021 May 27.

Department of Ophthalmology, Brooke Army Medical Center, San Antonio, TX, USA Department of Ophthalmology, Walter Reed National Military Medical Center, Bethesda, MD, USA Department of Surgery, Uniformed Services University of the Health Science, Bethesda, MD, USA Department of Ophthalmology, Wilford Hall Eye Center, San Antonio, TX, USA Department of Ophthalmology, Wake Forest Medical Center, Winston-Salem, NC, USA Department of Graduate Medical Education, Travis Air Force Base, Fairfield, CA, USA Department of Graduate Medical Education, Brooke Army Medical Center, San Antonio, TX, USA Warfighter Refractive Eye Surgery Program and Research Center, Fort Belvoir, Virginia, USA Retina Group of Washington D.C., Greenbelt, MD, USA Department of Surgery, Uniformed Services University of the Health Science, Bethesda, MD, USA Department of Ophthalmology, Madigan Army Medical Center, Tacoma, WA, USA.

Objective: To characterize the nature of posterior segment ocular injuries in combat trauma.

Methods: Eyes in the Walter Reed Ocular Trauma Database were evaluated for the presence of posterior segment injury. Final visual outcomes in open- versus closed-globe injuries and by zone of injury, and the types of posterior segment injuries in open- versus closed-globe injuries were assessed. Read More

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A novel technique to avoid intraoperative giant tear slippage: the bimanual double aspiration technique.

Int J Retina Vitreous 2021 May 27;7(1):42. Epub 2021 May 27.

Torrevieja Hospital, Road CV 95, s/n, 03186, Torrevieja, Alicante, Spain.

Background: The aim of this paper is to present a novel bimanual double aspiration technique to avoid intraoperative giant tear slippage. The major problem of giant retinal tears (GRT) surgery is the mobility of the posterior flap (slippage), which has been classically solved by the use of intraoperative perfluorocarbon liquid (PFCL). However, avoiding slippage of the posterior flap can be a serious technical challenge when the PFCL is removed, especially when a GRT circumference is > 180°. Read More

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Epimacular Inverted Retinal Flap Simulating an Epiretinal Membrane.

Ophthalmic Surg Lasers Imaging Retina 2021 May 1;52(5):293-295. Epub 2021 May 1.

A 66-year-old man was referred for management of a visually significant epiretinal membrane (ERM) with persistent cystoid macular edema after surgery for recurrent retinal detachment with proliferative vitreoretinopathy. The membrane was noted to be particularly thick and vascularized on preoperative optical coherence tomography. During the subsequent vitrectomy, the "membrane" was found to be an inverted retinal flap and successfully removed. Read More

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Massive Delayed Hemorrhagic Choroidal Detachment and Giant Retinal Tear Detachment Following Scleral-Fixated Akreos IOL.

Ophthalmic Surg Lasers Imaging Retina 2021 May 1;52(5):288-292. Epub 2021 May 1.

A 78-year-old woman underwent 25-gauge pars plana vitrectomy and scleral fixation for a dislocated intraocular lens in the left eye under general anesthesia. She developed massive hemorrhagic choroidal detachment 1 day later. A giant retinal tear detachment and proliferative vitreoretinopathy was noted at postoperative Week 7 and repaired with choroidal drainage, 240° peripheral retinectomy, perfluorocarbon liquid, endolaser, and silicone oil. Read More

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Management of complex retinal detachment from intraocular invasion of MIRAgel-a case report.

Am J Ophthalmol Case Rep 2021 Sep 14;23:101103. Epub 2021 May 14.

Department of Ophthalmology, Changhua Christian Hospital, Changhua, Taiwan.

Purpose: To retrospectively report a case of complex retinal detachment secondary to an intraocular episcleral hydrogel explant (MIRAgel, MIRA Inc., Waltham, MA, USA) invasion.

Observations: The severe vitreous inflammation, shifting nature of the subretinal fluid, and absence of proliferative vitreopathy 2 months following multiple surgeries for removal of fragmented MIRA gel in the present case made the diagnosis of complex retinal detachment. Read More

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September 2021

Polymeric hydrogel as a vitreous substitute: current research, challenges, and future directions.

Biomed Mater 2021 May 26. Epub 2021 May 26.

Department of Ophthalmology, West China Hospital of Medicine, Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu NO. 37 Guoxue Alley, Chengdu 610041, People's Republic of China., Chengdu city, Sichuan, 610041, CHINA.

Vitreoretinal surgery is an essential approach to treat proliferative diabetic vitreopathy, retinal detachment, retinal tear, ocular trauma, and macular holes. The removal of the natural vitreous and the replacement with substitutes are critical steps for retina reattachment. Vitreous substitutes including silicone oil (SiO), air, sulfur hexafluoride (SF6), and perfluoropropane (C3F8), have been widely applied in clinical practice. Read More

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Surgical failures after primary scleral buckling for rhegmatogenous retinal detachment: comparison of eyes with and without proliferative vitreoretinopathy.

Retina 2021 May 10. Epub 2021 May 10.

Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA.

Purpose: To compare proliferative vitreoretinopathy (PVR)-related surgical failure and non-PVR associated failure following scleral buckling (SB) for primary rhegmatogenous retinal detachment (RRD).

Methods: In this single-center, retrospective, consecutive case series, eyes with surgical failure after SB for primary RRD were identified. Eyes with surgical failure were categorized as PVR and non-PVR associated failure, and these groups were compared. Read More

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Posterior pole retinotomy for treatment of recurrent macular hole retinal detachment in highly myopic eyes: a pilot study.

BMC Ophthalmol 2021 May 17;21(1):217. Epub 2021 May 17.

Eye Center of Xiangya Hospital, Central South University, No. 87 Xiangya Road, KaiFu District, Changsha, 410008, Hunan, China.

Background: To investigate the feasibility and efficacy of posterior pole retinotomy to treat recurrent macular hole retinal detachment (MHRD) in highly myopic patients.

Methods: We performed a retrospective study and reviewed the medical records in our hospital between January 1, 2016 and December 31, 2018. Highly myopic patients who received posterior pole retinotomy with silicone oil tamponade for their recurrent MHRD after pars plana vitrectomy were included in the analysis. Read More

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Efficacy and Safety of Vitrectomy without Using Perfluorocarbon Liquids and Drainage Retinotomy Associated with Postoperative Positioning Based on Residual Subretinal Fluid for Rhegmatogenous Retinal Detachment.

J Ophthalmol 2021 20;2021:5588479. Epub 2021 Apr 20.

Department of Ophthalmology, Istituto Clinico Città Studi, Milan, Italy.

Medical records of 75 eyes from 75 consecutive patients with uncomplicated rhegmatogenous retinal detachment (RRD) who underwent pars plana vitrectomy (PPV) were analyzed. Inclusion criteria were patients with RRD who underwent primary 23- or 25-gauge PPV with air, gas, or SiO tamponade and performed by a single surgeon, no use of perfluorocarbon liquids (PFCL) and drainage retinotomy, and follow-up ≥ six months. Exclusion criteria were patients who underwent previous vitreoretinal surgery, proliferative vitreoretinopathy (PVR) more than grade B, giant tears, and encircling band associated with PPV. Read More

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The risk factors of the progression of rhegmatogenous retinal detachment on patients with the fourteen-day quarantine in the early period of COVID-19 outbreak.

BMC Ophthalmol 2021 May 15;21(1):215. Epub 2021 May 15.

Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing Tongren Hospital, Capital Medical University, No1. Dongjiaominxiang Street, Dongcheng District, Beijing, 100730, China.

Backgrounds: The COVID-19 Pandemic has a great impact on hospitals and patients. The 14-day quarantine caused surgery of rhegmatogenous retinal detachment (RRD) postponed. We aimed to explore the risk factors of RRD progression in a group of patients whose surgery was postponed during the top-level emergency response of COVID-19. Read More

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Risk Factors for Presence of Cystoid Macular Edema following Rhegmatogenous Retinal Detachment Surgery.

Curr Eye Res 2021 May 21:1-9. Epub 2021 May 21.

Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

: Cystoid macular edema (CME) following cataract surgery is a well-known entity. Less is known regarding the risk factors of developing CME following repair of rhegmatogenous retinal detachments (RRD).: This was a multi-institutional study of primary RRD surgeries from 1/1/2015 through 12/31/2015. Read More

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Four Cases of Rhegmatogenous Retinal Detachment That Recurred More than 10 Years after Initial Reattachment by Pars Plana Vitrectomy.

Case Rep Ophthalmol 2021 Jan-Apr;12(1):219-226. Epub 2021 Apr 12.

Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, Japan.

Purpose: The purpose of this report was to present our findings in 4 cases of rhegmatogenous retinal detachment (RRD) that recurred 10, 11, 12, and 17 years after a reattachment surgery by pars plana vitrectomy (PPV).

Methods: Four cases of a recurrent RRD had undergone scleral buckling surgery and vitrectomy.

Patients: The recurrence of the RRD was observed 10-17 years after the successful attachment by PPV. Read More

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Plumbagin Inhibits Proliferation, Migration, and Invasion of Retinal Pigment Epithelial Cells Induced by FGF-2.

Tissue Cell 2021 Apr 28;72:101547. Epub 2021 Apr 28.

Department of Ophthalmology, The second Hospital of Hebei Medical University, Shijiazhuang, 05000, China. Electronic address:

Proliferative vitreoretinopathy (PVR) is a serious ophthalmic disease and characterized by the formation of proliferative membranes by retinal pigment epithelial (RPE) cells. In PVR, the contraction and traction of the fibrocellular membranes cause retinal detachment, which can cause reduction surgery for retinal detachment to fail. Fibroblast growth factor-2 (FGF-2) causes RPE cells to form extracellular matrix (ECM), promotes chemotaxis, mitosis, and positively promotes the disease process of PVR. Read More

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Vitrectomy Due to Vitreous Hemorrhage and Tractional Retinal Detachment Secondary to Eales' Disease

Turk J Ophthalmol 2021 04;51(2):102-106

İstanbul Retina Institute, İstanbul, Turkey

Objectives: To investigate visual and anatomical outcomes of vitreoretinal surgeries in patients with Eales' disease.

Materials And Methods: In this retrospective study, 22 eyes of 21 patients with vitreous hemorrhage (VH) or tractional retinal detachment (TRD) secondary to Eales' disease who underwent vitreoretinal surgery between January 1997 and December 2015 and had at least 1 year of follow-up were included.

Results: The mean best corrected visual acuity (BCVA) was significantly higher at final visit (0. Read More

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Isolated Central Epiretinal Membrane: A Rare Complication of Fovea-Sparing Internal Limiting Membrane Peeling Technique.

J Ophthalmol 2021 14;2021:6654604. Epub 2021 Apr 14.

Department of Ophthalmology, Changhua Christian Hospital, Changhua, Taiwan.

Purpose: To report a rare complication presenting as an isolated central epiretinal membrane (ERM) related to fovea-sparing internal limiting membrane (ILM) peeling technique.

Methods: Five patients who received fovea-sparing ILM peeling were enrolled. Postoperatively, an isolated central ERM developed. Read More

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Macular internal limiting membrane peel for eyes undergoing vitrectomy for retinal detachment: Rationalizing selection based on the severity of proliferative vitreoretinopathy.

Indian J Ophthalmol 2021 05;69(5):1356-1357

Department of Vitreo-retina and Uveitis, Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India.

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Vitrectomy without encircling band for rhegmatogenous retinal detachment with inferior break utilizing 3D heads up viewing system.

Indian J Ophthalmol 2021 05;69(5):1208-1212

Dr. R. P. Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.

Purpose: This study aimed to determine the anatomical and functional outcomes of pars plana vitrectomy without encircling band for primary rhegmatogenous retinal detachments with inferior breaks utilizing 3D heads up viewing system.

Method: This prospective, single-center study included 22 consecutive eyes with primary rhegmatogenous retinal detachments with only inferior breaks with proliferative vitreoretinopathy (PVR) CP2 or less, who underwent pars plana vitrectomy without encircling band, with silicon oil as tamponade. All surgeries were performed by a single surgeon. Read More

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Adjunctive serial post-operative intravitreal methotrexate injections in the management of advanced proliferative vitreoretinopathy.

Graefes Arch Clin Exp Ophthalmol 2021 Apr 26. Epub 2021 Apr 26.

Asociados de Macula Vitreo Y Retina de Costa Rica Primer Piso Torre Mercedes Paseo Colón, San José, Costa Rica.

Purpose: To assess the effects of weekly post-operative intravitreal methotrexate injections on eyes with grade C proliferative vitreoretinopathy (PVR) that underwent surgical repair.

Methods: Retrospective case-control study of 16 eyes with retinal detachment and grade C PVR. Seven eyes received weekly intravitreal MTX injections post-operatively as an adjunct and 9 eyes served as the control. Read More

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Retinotomy and retinectomy for anterior inferior proliferative vitreoretinopathy: Can visual outcome be improved?

Eur J Ophthalmol 2021 Apr 22:11206721211012848. Epub 2021 Apr 22.

Istanbul Retina Institute, Istanbul, Turkey.

Purpose: To describe the treatment outcomes and prognostic factors of retinotomy/retinectomy for rhegmatogenous retinal detachment (RD) complicated anterior inferior proliferative vitreoretinopathy (PVR).

Methods: Retrospective, nonrandomized, single-center case series. The outcomes of 126 cases of retinotomy/retinectomy for RD complicated by advanced (Grade C) anterior inferior PVR managed consistently by one surgeon during a 15-year period were evaluated. Read More

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A simple new technique for the induction of residual posterior vitreous cortex removal and membrane peeling.

Int J Ophthalmol 2021 18;14(4):622-625. Epub 2021 Apr 18.

Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai 200031, China.

Aim: To describe a quick, cost-effective alternative to using a scraper to remove the residual posterior vitreous cortex and create an inner limiting membrane (ILM) flap during vitrectomy.

Methods: The surgical technique and a retrospective interventional single-center series of cases were described. A hook was made on the tip of a conventional syringe needle (outer diameter, 0. Read More

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Versatility of use of fibrin glue in wound closure and vitreo-retinal surgery.

Int J Retina Vitreous 2021 Apr 15;7(1):33. Epub 2021 Apr 15.

Retina and Vitreus Department, Asociacion para Evitar la Ceguera en México, IAP, Vicente García Torres 46, Col. Barrio San Lucas, Coyoacan, 04030, Mexico City, Mexico.

Background: Fibrin glue is an absorbable blood-derived product, a biological tissue adhesive which imitates the final stages of the coagulation cascade, it produces a firm clot, forming a seal along the whole length of the wound, the resultant fibrin clot degrades physiologically into granulation tissue 2 weeks after the application. Biological glue has been used extensively in many forms of surgical procedures. Its use in eye surgery has grown lately as we have evidence that showed it was effective in securing conjunctival grafts in pterygium surgery, in securing wounds after glaucoma surgery and more importantly in 20G and 23G vitrectomy. Read More

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Re: Concept and application of relaxing radial retinectomy for retinal detachment with advanced proliferative vitreoretinopathy.

Int J Retina Vitreous 2021 Apr 9;7(1):29. Epub 2021 Apr 9.

Department of Ophthalmology, St Thomas' Hospital, London, UK.

The following is a response to the recent review article by Girsang and colleagues (Int J Retina Vitreous. 2020;6:46), who describe concept and application of relaxing radial retinectomy for retinal detachment with advanced proliferative vitreoretinopathy. We discuss the distribution of the retinal nerve fiber layer, an aspect not touched on by the authors, and the importance of its consideration in determining visual field outcomes when performing retinectomy. Read More

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