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Am J Ophthalmol Case Rep 2019 Mar 9;13:131-135. Epub 2019 Jan 9.

Department of Ophthalmology, Croix-Rousse University Hospital, Hospices Civils de Lyon, Lyon, France.

Purpose: To present the case of a patient with a hypertensive choroidopathy and her follow-up using multimodal imaging; and to assess how wide-field swept-source (SS) Optical Coherence Tomography Angiography (OCTA) contributes to detecting the areas of hypoperfusion.

Observations: A 25-year-old white woman with terminal renal insufficiency, myopericarditis, and cerebrospinal fluid pressure of 37 mmHg indicating intracranial hypertension, presented with a painless loss of vision in both eyes. Her blood pressure was 190/135 mmHg. Read More

Melanoma Res 2019 Jan 16. Epub 2019 Jan 16.

Department of Ophthalmology, Leiden University Medical Center.

Uveal melanoma (UM), the most common primary intraocular tumour, is often complicated by exudative retinal detachment (RD). Sometimes, this exudative RD is mistaken for a rhegmatogenous detachment and is subsequently treated with vitrectomy with silicone oil (SiOil) tamponade. As SiOil prevents ultrasound imaging, the diagnosis, treatment planning and/or follow-up of UM underlying the detachment are often severely hindered by the SiOil. Read More

Oncol Lett 2019 Jan 16;17(1):1274-1278. Epub 2018 Nov 16.

Department of Ophthalmology, Peking University People's Hospital, Beijing 100044, P.R. China.

Schwannoma is a proliferation of neoplastic Schwann cells. Schwannomas comprise 8-10% of all primary intracranial tumors. Primary intraorbital schwannoma arising from the ciliary nerves in the uvea, which accounts for 1-2% of all intracranial tumors, is a rare intraocular neoplasm. Read More

Taiwan J Ophthalmol 2018 Oct-Dec;8(4):222-236

Department of Ophthalmology, The University of Hong Kong, Hong Kong.

In this review, we present a concise summary of the more commonly seen types of retinal detachments (RDs) that one can encounter in pediatric patients. A spectrum of diseases from rhegmatogenous RD in Stickler syndrome, Marfan syndrome, and choroidal coloboma to exudative RD in Coats disease, to tractional RD in persistent fetal vasculature, and combined RDs in familial exudative vitreoretinopathy are described with the management pearls for each. Read More

Retina 2018 Dec 31. Epub 2018 Dec 31.

Department of Ophthalmology, University of Padova, Padova, Italy.

Purpose: To evaluate the long-term results of autologous retinal pigment epithelium (RPE) and choroid transplantation (RPE-choroid patch) for exudative and atrophic maculopathies.

Methods: Consecutive chart review of 120 eyes, which underwent RPE-choroid patch, from 2007 to 2017 for RPE atrophy or choroidal neovascular membrane secondary to exudative and hemorrhagic age-related macular degeneration, myopia, angioid streaks, and laser. Eyes were tested with best-corrected visual acuity (BCVA), reading ability, optical coherence tomography, fluorescein angiography and indocyanine green angiography, autofluorescence, and microperimetry. Read More

Saudi J Ophthalmol 2018 Oct-Dec;32(4):355-357. Epub 2018 Feb 23.

Pathology Service, Anatomic Pathologist, Ophthalmic Pathologist, "Hospital Español de México", Mexico City, Mexico.

We describe the clinic, image, and histopathologic features of a well differentiated neuroendocrine carcinoma (carcinoid tumour) metastatic to choroid and ciliary body in a 52-year-old Mexican Mestizo man. The ophthalmologic examination showed an inferior choroidal mass accompanied by exudative retinal detachment. Ultrasound B-Scan study revealed a diffuse thickened choroid with overlying serous retinal detachment, ultrasound A-Scan revealed a high internal reflectivity solid lesion. Read More

Indian J Ophthalmol 2019 Jan;67(1):167-170

Advanced Eye Center, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.

In this report, we describe a rare case of a 44-year-old Asian male with acute central serous chorioretinopathy (CSC) with bullous exudative retinal detachment. Endocrinology evaluation revealed hypothalamic-pituitary-adrenal axis suppression with low serum cortisol. Furthermore, neuroimaging revealed the presence of a pituitary microadenoma. Read More

Int Ophthalmol 2018 Dec 18. Epub 2018 Dec 18.

S. Anna Clinical Institute, Via del Franzone, 31, 25127, Brescia, Italy.

Purpose: To demonstrate the safety and efficacy of partial thickness sclerectomies to treat exudative retinal detachment secondary to choroidal hemangioma, non-suitable with photodynamic therapy in a 5-year-old child with Sturge-Weber syndrome.

Methods: A 5 year-old child presented exudative retinal detachment secondary to choroidal subfoveal diffuse hemangioma. The child was non-compliant to undergo a photodynamic therapy. Read More

Ocul Immunol Inflamm 2018 Dec 17:1-3. Epub 2018 Dec 17.

a Advanced Eye Centre , Post Graduate Institute of Medical Education and Research , Chandigarh , India.

Purpose: To report two unique cases of spontaneous uveal effusion syndrome (UES) from the same family.

Methods: The patients included father (54 years old) and a daughter (23 years old). The father presented 7 years ago with bilateral exudative retinal detachment, nanophthalmic eyes (axial length 16. Read More

Vestn Oftalmol 2018 ;134(5. Vyp. 2):289-293

Research Institute of Eye Diseases, 11, A, B Rossolimo St., Moscow, Russian Federation, 119021.

Age-related macular degeneration (AMD) is a retinal disease associated with older age; it affects macula and leads to deterioration of central vision. Geographic atrophy (GA) is described as advanced stage AMD. Essentially, GA is the loss of some areas of retinal pigment epithelium (RPE), which is necessary for normal functioning of the retina as it transports nutrients and ions, helps with production of growth factors and protects from photo-oxidation. Read More

Retina 2018 Nov 16. Epub 2018 Nov 16.

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.

Purpose: To investigate retinal pigment epithelium (RPE) tears in patients with polypoidal choroidal vasculopathy.

Method: A retrospective review of polypoidal choroidal vasculopathy cases with confirmed RPE tears was conducted. Patients' comprehensive clinical data were collected and analyzed. Read More

Indian J Ophthalmol 2018 Dec;66(12):1802-1807

Division of Ophthalmology, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Israel.

Purpose: A prospective cohort study investigating the effect of posterior vitreous detachment (PVD) on the efficacy of intravitreal bevacizumab for exudative age-related macular degeneration (AMD), in view of evidence that the vitreoretinal interface impacts the severity of the disease.

Methods: Treatment-naïve AMD eyes with (+) complete PVD and without (-) PVD on ultrasonography received three monthly and then pro re nata bevacizumab injections. Best-corrected visual acuity (BCVA) on Snellen charts and optical coherence tomography (OCT) findings were recorded for 12 months. Read More

Int J Ophthalmol 2018 18;11(11):1829-1834. Epub 2018 Nov 18.

Department of Ophthalmology, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.

Aim: To clinically differentiate nanophthalmos (NO) and posterior microphthalmos (PM) and to explore the mechanisms related to papillomacular folds (PMF).

Methods: Medical records of 34 unrelated patients with microphthalmos (54 eyes) from April 2009 to October 2017 were retrospectively reviewed.

Results: Fourteen eyes of 7 unrelated patients with NO and PM were included in the study. Read More

Ophthalmic Genet 2018 Dec 8;39(6):754-758. Epub 2018 Nov 8.

a Retinal Consultants , Des Plaines , IL , USA.

Background: Loeys-Dietz syndrome (LDS) is a connective tissue disorder that has phenotypic overlap with Marfan syndrome. In LDS, the aortic root dissections can be more aggressive and occur at a younger age than Marfan syndrome.

Materials And Methods: Review of two cases. Read More

Melanoma Res 2018 Oct 31. Epub 2018 Oct 31.

Centre universitaire d'ophtalmologie (CUO).

Nearly half of choroidal melanomas progress to the metastatic stage at 15 years. The purpose of our study was to evaluate the prognostic value of tumour-height regression rate in medium-sized choroidal melanomas treated with iodine-125 brachytherapy. A retrospective cohort study was performed on 128 patients with medium-sized choroidal melanoma who were treated with iodine-125 brachytherapy. Read More

Photodiagnosis Photodyn Ther 2018 Dec 28;24:372-376. Epub 2018 Oct 28.

Department of Ophthalmology, the First Affiliated Hospital of China Medical University. No. 155 Nanjing Bei Street, Heping District, Shenyang City, Liaoning Province, 110001, People's Republic of China; Department of Ophthalmology, Tacheng area people's Hospital, No. 22, Wenhua road Tacheng City, the Xinjiang Uygur Autonomous Region, People's Republic of China; Diabetic Eye Center of Liaoning province. No. 155 Nanjing Bei Street, Heping District, Shenyang City, Liaoning Province, 110001, People's Republic of China; The Key Laboratory of Endocrine diseases in Liaoning Province, The First Hospital of China Medical University, No. 155 Nanjing Bei Street, Heping District, Shenyang City, Liaoning Province, 110001, People's Republic of China. Electronic address:

The purpose of this study is to describe the effects and complications of photodynamic therapy (PDT) on Chinese patients with circumscribed choroidal hemangioma (CCH). In this retrospective study, 22 CCH patients who underwent PDT performed 15 min after the injection of intravenous verteporfin (6 mg/m2)with multiple 83-second laser spots at 689 nm (50 J/cm2) were studied. Fluorescein angiography and/or indocyanine green angiography, B-scan ultrasonography and optical coherence tomography were performed in all patients. Read More

BMC Ophthalmol 2018 Oct 26;18(1):277. Epub 2018 Oct 26.

Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, China.

Background: The present study reported a case of juxtapapillary retinal capillary hemangioma (JRCH) that was successfully treated by two sessions of full-fluence photodynamic treatment (PDT) with good visual outcome.

Case Presentation: A 19-year-old male patient presented progressive deterioration of the vision of right eye due to the presence of exudative macular detachment associated with JRCH. The best-corrected visual acuity (BCVA) had decreased from 1. Read More

J Ophthalmic Inflamm Infect 2018 Oct 17;8(1):18. Epub 2018 Oct 17.

Department of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, Monastir, Tunisia.

Background: Acute multifocal retinitis is a rare condition that has been considered to be often idiopathic. The purpose of this study was to analyze clinical features and causes of acute multifocal retinitis.

Results: This study is a retrospective review of the charts of 35 patients with acute multifocal retinitis. Read More

Melanoma Res 2018 Oct 12. Epub 2018 Oct 12.

Department of Ophthalmology, Croix-Rousse University Hospital.

The aim of this study was to evaluate metastatic latency and survival after the occurrence of metastases in patients with choroidal/ciliary body melanoma treated with proton therapy. This was a retrospective cohort study. All consecutive patients with choroidal/ciliary body melanoma treated with proton therapy between 1991 and 2010 were included. Read More

BMC Ophthalmol 2018 Oct 11;18(1):264. Epub 2018 Oct 11.

Department of Ophthalmology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho Kita-ku, Okayama City, Okayama, 700-8558, Japan.

Background: Coats disease is a retinal disease characterized by exudative retinal detachment due to abnormal retinal blood vessels. Coats disease is generally treated using laser photocoagulation and cryotherapy to ablate the abnormal retinal blood vessels. However, if abnormal blood vessels are present near the posterior pole of the eye and there is a severe exudative change there, it is difficult to perform these standard treatments. Read More

J Glaucoma 2019 Feb;28(2):e21-e23

Department of Ophthalmology, Gazi University School of Medicine, Ankara, Turkey.

Purpose: The main purpose of this study was to report a case of panscleritis after gonioscopy-assisted transluminal trabeculotomy (GATT).

Methods: We describe the case of a 33-year-old man with a history of unilateral anterior uveitis and glaucoma, who developed panscleritis after GATT surgery.

Results: Uneventful GATT surgery was performed in a glaucomatous left eye. Read More

BMC Ophthalmol 2018 Sep 5;18(1):238. Epub 2018 Sep 5.

Departments of Gastroenterology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China.

Background: Endogenous endophthalmitis could lead to a devastating outcome without a prompt and appropriate management. We report a case of advanced endogenous Klebsiella pneumoniae endophthalmitis with extensive subretinal abscess that was successfully treated with a vitrectomy.

Case Presentation: A systemically well 61-year-old man complained of ocular pain and visual decrease in his right eye for eighteen days. Read More

BMJ Case Rep 2018 Aug 27;2018. Epub 2018 Aug 27.

University hospitals of Plymouth, Royal Eye Infirmary, Derriford, Plymouth, UK.

Chikungunya is a systemic viral disease transmitted to humans by infected mosquitoes in endemic areas of Africa, Asia and more recently in the Americas. Chikungunya infection produces a sudden onset of fever, joint pains and erythematous skin eruption. A plethora of ocular manifestations have been described ranging from a non-specific conjunctivitis to exudative retinal detachment. Read More

Ophthalmic Surg Lasers Imaging Retina 2018 Aug;49(8):625-628

Exudative and tractional retinal detachments have been reported as late sequelae of retinopathy of prematurity (ROP). The authors report a case of unilateral retinal detachment in a 19-year-old patient with history of peripheral ablation for ROP in the contralateral eye. This late reactivation is likely due to persistent avascular retina producing constant low levels of vascular endothelial growth factor. Read More

Klin Monbl Augenheilkd 2018 Sep 10;235(9):994-1000. Epub 2018 Aug 10.

Klinik für Augenheilkunde, Campus Benjamin Franklin, Charité Universitätsmedizin Berlin.

PEHCR (peripheral exudative haemorrhagic chorioretinopathy) is a disease manifested clinically, particularly by subretinal bleeding, retinal exudates, retinal pigment epithelium detachments (RPE detachments), exudative retinal detachment and sub-RPE bleeding. The PEHCR lesion is often characterized by its polypoidal pattern, which is very similar to PCV (polypoidal choroidal vasculopathy) polyps. Diagnosis is best made with a wide-field ICGA (indocyanine green angiography). Read More

Am J Ophthalmol Case Rep 2018 Sep 17;11:153-157. Epub 2018 Apr 17.

Vitreoretinal Division King Khaled Eye Specialist Hospital, Al Oroubah St, Riyadh, Saudi Arabia.

Purpose: To describe two young Saudi brothers with bilateral progressive retinal arterial aneurysms and a subtotal exudative retinal detachment with Coats-like presentation in the older sibling as the initial presentation of Familial Retinal Arterial Macroaneurysms (FRAM).

Observations: Two young Saudi brothers with a family history of consanguinity presented with the classic clinical presentation and genetic identification of FRAM. In this report, we describe the presence of prominent peripheral retinal capillary changes mimicking Coats' disease. Read More

Retin Cases Brief Rep 2018 Aug 1. Epub 2018 Aug 1.

Ophthalmology Department, University of California School of Medicine, San Francisco, Koret Vision Research Center, San Francisco, California.

Purpose: To present the scope of prenatal diagnosis and early treatment of patients with clinically heterogeneous phenotypic retinal dysplasia associated with NDP gene variants.

Methods: Retrospective. Review of electronic medical records. Read More

Retin Cases Brief Rep 2018 Jul 18. Epub 2018 Jul 18.

Department of Ophthalmology, Seattle Children's Hospital, Seattle, Washington.

Background: Few cases of exudative retinal detachments have been reported in the literature after laser treatment for retinopathy of prematurity, and none of the cases include optical coherence tomography images.

Methods: Case report.

Results: A 469-g birth weight, 25-week gestational age baby girl at 35-week postmenstrual age received a retinal laser (1,724 spots in the right eye and 1,287 spots in the left eye) for bilateral Stage 3 Zone II plus disease retinopathy of prematurity. Read More

Ophthalmic Surg Lasers Imaging Retina 2018 Jul;49(7):534-539

The authors describe the imaging characteristics and progression of a type 2 choroidal neovascular membrane (CNV) using swept-source optical coherence tomography (SS-OCTA). A 27-year-old male presented with an active possible tubercular choroidal granuloma associated with exudative retinal detachment in the right eye. The patient received anti-tubercular drugs, oral corticosteroids, and intravitreal bevacizumab and showed complete resolution in 3 months. Read More

Eye (Lond) 2018 11 12;32(11):1731-1739. Epub 2018 Jul 12.

St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.

Purpose: To describe treatment outcomes in a cohort of Caucasian patients with polypoidal choroidal vasculopathy (PCV).

Methods: Clinical charts from 48 eyes of 45 Caucasian patients with PCV were retrospectively reviewed. All cases were diagnosed with indocyanine green angiography. Read More

Am J Ophthalmol Case Rep 2018 Sep 4;11:72-74. Epub 2018 Jun 4.

Department of Ophthalmology, Wake Forest School of Medicine, 1 Medical Center Blvd, Winston-Salem, NC 27157, USA.

Purpose: To report the only known case, to our knowledge, of bilateral exudative retinal detachments in the setting of thrombotic microangiopathy associated with intravenous abuse of extended-release oxymorphone (Opana ER).

Observations: A 35-year-old male presented with headaches and acute, painless vision loss in the context of daily IV abuse of crushed oral Opana ER. The patient was found to have microangiopathic hemolytic anemia (MAHA), acute kidney injury in conjunction with hypertensive crisis and bilateral exudative retinal detachments. Read More

Clin Exp Optom 2018 Jul 4. Epub 2018 Jul 4.

School of Optometry and Vision Science, The University of New South Wales, Kensington, New South Wales, Australia.

Choroidal detachments occur when there is an accumulation of fluid or blood in the suprachoroidal space, a potential space situated between the choroid and the sclera. They are an uncommon ocular pathology. The most common cause of choroidal detachment is secondary to trabeculectomy; however, there are other causes such as trauma and inflammation. Read More

Ocul Immunol Inflamm 2018 Jul 3:1-12. Epub 2018 Jul 3.

b Department of Ophthalmology , Northwestern University, Feinberg School of Medicine , Chicago , Illinois , USA.

Purpose: To describe tuberculous uveitis (TU) presenting as a bullous retinal detachment (RD) and to perform a comprehensive literature review on TU with similar features.

Methods: Observational case report and systematic literature review.

Results: An 84-year-old woman presented with bilateral granulomatous uveitis and bullous RD in the left eye. Read More

Int Ophthalmol 2018 Jun 8. Epub 2018 Jun 8.

Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, No. 23, Paidarfard St., Pasdaran Ave., Tehran, 16666, Iran.

Purpose: Presentation of two typical cases with characteristic leopard retinopathy secondary to bilateral diffuse uveal melanocytic proliferation (BDUMP) and idiopathic uveal effusion syndrome (IUES) and brief review of the literature about leopard spot retinopathy.

Case Report: A 43-year-old women, who was a known case of ovarian carcinoma, referred with gradual bilateral visual loss. In ophthalmic examination, subretinal fluid, multiple patchy subretinal hyperpigmented lesions and leopard spot chorioretinopathy were evident in her both eyes. Read More

Oman J Ophthalmol 2018 May-Aug;11(2):181-183

Chairman and Managing Director, Chief Vitreo-Retina Surgeon, Aditya Jyot Eye Hospital, Mumbai, Maharashtra, India.

Surgical management of advanced coats' disease has always been a challenge to a surgeon. Various different techniques have been tried. With the advancement in surgical instruments and machines, surgeons are now modifying older surgical techniques. Read More

BMJ Case Rep 2018 Jun 17;2018. Epub 2018 Jun 17.

Department of ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, Delhi, New Delhi, India.

Graefes Arch Clin Exp Ophthalmol 2018 Jun 16. Epub 2018 Jun 16.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, People's Republic of China.

Background: To evaluate the clinical outcome of 25-gauge lens-sparing vitrectomy with dissection of retrolental adhesions on the peripheral retina for familial exudative vitreoretinopathy in infants.

Methods: Fifty-one eyes of 39 infants with familial exudative vitreoretinopathy associated with retrolental adhesions on the peripheral retina, retinal fold with macular detachment, and partial lens opacity. A 25-gauge lens-sparing vitrectomy was performed, and retrolental adhesions between the peripheral retina and the posterior lens capsule were surgically dissected. Read More

Medicine (Baltimore) 2018 Jun;97(23):e11048

Department of Ophthalmology, Osaka Medical College, Takatsuki-City, Osaka, Japan.

Rationale: To report a case of familial exudative vitreoretinopathy (FEVR) complicated with full-thickness macular hole (FTMH).

Patient Concerns: A 39-year-old male presented after becoming aware of metamorphopsia in his left eye.

Diagnoses: Fundus examination showed a retinal avascular area, retinal vascular abnormality, and yellow exudation at the peripheral retina in both eyes. Read More

Retina 2018 May 8. Epub 2018 May 8.

Department of Biomedical and Clinical Science "Luigi Sacco," Eye Clinic, Luigi Sacco Hospital, University of Milan, Milan, Italy.

Purpose: To describe the imaging features of choroidal melanoma using swept-source optical coherence tomography angiography (SS-OCT-A) and to evaluate its ability to display tumor intrinsic vasculature.

Methods: Consecutive patients diagnosed with choroidal melanoma underwent a complete ophthalmic evaluation, including best-corrected visual acuity, color fundus photography, B-scan ultrasound, fluorescein angiography, indocyanine green angiography, and SS-OCT-A (PLEX Elite 9000; Carl Zeiss Meditec, Inc, Dublin, CA).

Results: Twenty-two eyes of 22 consecutive patients were included in the study; 11 cases (50%) were treatment naive. Read More

PLoS One 2018 31;13(5):e0197088. Epub 2018 May 31.

Department of Ophthalmology, Chang Gung Memorial Hospital Linkou Medical Center, Taoyuan, Taiwan.

Background: To investigate the treatment outcomes and predictors of response to photodynamic therapy (PDT) in patients with symptomatic circumscribed hemangioma (CCH).

Methods: This retrospective case series examined 20 patients with symptomatic CCH (10 submacular CCHs and10 juxtapapillary CCHs) who underwent standard PDT (wavelength: 662 nm; light dose: 50J/cm2; exposure time: 83 sec) with verteporfin (6mg/m2), either as monotherapy (n = 9) or in association with other treatments (n = 11), of which 7 received intravitreal injections (IVI) of anti-vascular endothelial growth factor (anti-VEGF). A post-PDT improvement of at least two lines in best-corrected visual acuity (BCVA) was the primary outcome measure. Read More

Eur J Ophthalmol 2018 Nov 22;28(6):722-730. Epub 2018 May 22.

The New York Eye Cancer Center, New York, NY, USA.

Purpose:: To describe the patterns of regression of choroidal melanoma after treatment with plaque brachytherapy.

Methods:: Retrospective interventional case series including 170 consecutive patients treated with Pd eye plaque radiation for choroidal melanoma. Outcome measures were changes in tumor thickness, surface characteristics, tumor vascularity, ultrasonography, fluorescein angiography, optical coherence tomography, and histopathology. Read More

Indian J Ophthalmol 2018 06;66(6):863-865

Department of Vitreo-retina, Dr Shroff's Charity Eye Hospital, New Delhi, India.

A 43-year-old male with chronic Vogt-Koyanagi-Harada syndrome (VKH) presented with subfoveal choroidal neovascular membrane (CNVM) in the right eye with no evidence of active inflammation. He underwent intravitreal bevacizumab and dexamethasone injections. Postinjection he developed fresh keratic precipitates and exudative retinal detachment (RD). Read More

Am J Ophthalmol Case Rep 2018 Jun 10;10:221-225. Epub 2018 Mar 10.

Sankara Nethralaya, Medical Research Foundation, Chennai, India.

Purpose: To report two rare cases of chronic myeloid leukemia (CML) on tyrosine kinase inhibitors presenting as bilateral serous retinal detachment and ocular inflammation, simulating Vogt-Koyanagi-Harada (VKH) disease.

Methods: Case series and review of literature.

Result: Two young patients (one male and one female) with CML on treatment with tyrosine kinase inhibitors (imatinib and dasatanib) under remission presented with bilateral sudden vision loss. Read More

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2018 May 16. Epub 2018 May 16.

Department of Ophthalmology for Children and Adults, Second Faculty of Medicine, Charles University, Prague and University Hospital Motol, Prague, Czech Republic.

Aim: Presentation of the efficacy of infrared laser for the treatment of retinal capillary hemangioma (RCH).

Methods: The treatment and follow-up of nine eyes (fourteen tumors of different sizes and localizations) in seven patients (five children) with RCH. Infrared diode laser (810 nm) was used for modified transpupillary thermotherapy (TTT) in long exposition mode and power between 200 and 1200 mW with a beam diameter of 2 mm (indirect ophthalmoscope, +28 D or +40 D lens) or 0. Read More

Bratisl Lek Listy 2018 ;119(5):275-277

Purposes: To inform about a case of Revesz syndrome (RS) with initial ophthalmological symptomatology of severe proliferative vitreoretinopathy of the left eye (LE). After the aplastic anemia had developed, RS was established. The exudative retinopathy was successfully treated with photocoagulation on the right eye (RE). Read More

Zhonghua Yan Ke Za Zhi 2018 Apr;54(4):270-276

Department of Ophthalmology, Peking Union Medical College Hospital, Beijing 100730, China.

To evaluate the efficacy of vitrectomy and etiological diagnosis in the treatment of fungal endophthalmitis. A retrospective survey was done on the clinical manifestation, etiological diagnosis and treatment efficacy of 15 patients (15 eyes) who had been diagnosed with fungal endophthalmitis at the inpatient department of Peking Union Medical College Hospital during 2002-2015. A total of 15 eyes of 15 patients, 3 male and 12 female patients, were included in this study. Read More

Ocul Immunol Inflamm 2018 May 10:1-4. Epub 2018 May 10.

e Uvea and Ocular Pathology, Sankara Nethralaya , Chennai , India.

Purpose: To describe a case of Nocardia subretinal abscess, which posed a diagnostic challenge due to the presence of mycobacterial genome in sample obtained from fine needle aspiration biopsy (FNAB).

Methods: A retrospective chart review.

Results: A 25-year-old male presented with sudden, painless onset diminution of vision of left eye and found to have placoid patch of choroiditis just temporal to the macula in right eye and showed vitritis, subretinal abscess with exudative retinal detachment and vitreous hemorrhage in left eye. Read More

Pan Afr Med J 2017 22;28:313. Epub 2017 Dec 22.

Université Mohamed V Souissi, Service d'Ophtalmologie A, Hôpital des Spécialités, CHU IBN Sina, Rabat, Maroc.

We here report the case of a 27-year old patient, followed-up in our Department for treatment of chronic Vogt-Koyanagi-Harada disease ( VKH disease). Fundus examination showed depigmentation of the retinal pigment epithelium and of the choroid, appearing as a pseudotumoral peripapillary lesion. Vogt-Koyanagi-Harada disease is a multisystem disorder, characterized by bilateral granulomatous panuveitis with serous exudative multifocal retinal detachment. Read More

Asia Pac J Ophthalmol (Phila) 2018 May-Jun;7(3):156-159. Epub 2018 Mar 27.

Department of Ophthalmology, Kindai University Faculty of Medicine, Osaka, Japan.

Coats disease is a sporadic, chronic retinal vascular disorder with telangiectatic and aneurysmal retinal vessels, with retinal exudation and retinal detachment in severe cases. Various treatment modalities have been used, including laser therapy, cryotherapy, anti‒vascular endothelial growth factor (VEGF) therapy, and surgery. Anti-VEGF therapy seems to be effective in reducing exudative changes and is often combined with other treatment modalities. Read More

Asia Pac J Ophthalmol (Phila) 2018 May-Jun;7(3):176-182. Epub 2018 Apr 9.

Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts.

Familial exudative vitreoretinopathy (FEVR) is a heritable vitreoretinopathy characterized by anomalous retinal vascular development. The principal feature of the disease is an avascular peripheral retina. This in turn can cause further pathological changes including neovascularization, exudation, hemorrhage, and retinal detachment. Read More