26,883 results match your criteria Retinal Detachment


Examiner Position in Ocular Point-of-Care Ultrasound: A Proposed Technique.

J Emerg Med 2019 Apr 16. Epub 2019 Apr 16.

Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

Background: Ocular point-of-care ultrasound (POCUS) is a fast and safe non-invasive procedure used to evaluate the structural integrity and pathology of the eye. Ocular POCUS can be used for evaluation of posterior chamber and orbital pathology, including retinal detachment, vitreous detachment or hemorrhage, foreign body, lens dislocation, and increased intracranial pressure.

Discussion: The purpose of this brief communication is to describe a technique for conducting an ocular POCUS that may in some cases be easier and more comfortable by adjusting the position of the sonographer relative to the patient. Read More

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http://dx.doi.org/10.1016/j.jemermed.2019.03.027DOI Listing

Functional analysis of miR-21-3p, miR-30b-5p and miR-150-5p shuttled by extracellular vesicles from diabetic subjects reveals their association with diabetic retinopathy.

Exp Eye Res 2019 Apr 16. Epub 2019 Apr 16.

Dept of Medical Sciences, University of Turin, Italy. Electronic address:

Microvascular dysfunctions due to altered interactions between endothelial cells (ECs) and pericytes are key-events in the pathogenesis of diabetic retinopathy. Extracellular vesicles (EVs) derived from mesenchymal stem cells cultured in diabetic-like conditions enter pericytes, cause their detachment and migration, and stimulate angiogenesis. We recently showed that EVs from diabetic patients with retinopathy have different miRNA profiling patterns from healthy controls, and determine features of retinopathy in in vitro models of retinal microvasculature. Read More

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http://dx.doi.org/10.1016/j.exer.2019.04.015DOI Listing

Reviving the lost art of scleral buckling surgery for rhegmatogenous retinal detachment: evaluation of risk factors of detachments, poor physiological outcomes, and perspective from a developing country.

Ther Adv Ophthalmol 2019 Jan-Dec;11:2515841419838662. Epub 2019 Apr 7.

Lumbini Eye Institute, Lumbini, Nepal.

Purpose: To evaluate the primary anatomic and physiological success of scleral buckling surgery for rhegmatogenous retinal detachment and factors influencing its outcomes.

Methods: This is a prospective analytical study of 92 eyes that underwent scleral buckling at the Lumbini Eye Institute and Research Center, in Lumbini, Nepal. Parameters evaluated which could influence the outcome of the surgery included the lens status, duration of symptoms, locations of breaks, the extent of retinal detachment, and preoperative proliferative vitreoretinopathy. Read More

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http://dx.doi.org/10.1177/2515841419838662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454650PMC
April 2019
1 Read

Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma.

Cochrane Database Syst Rev 2019 Apr 19;4:CD011875. Epub 2019 Apr 19.

Ophthalmology, Singapore National Eye Centre, Singapore, Singapore.

Background: Glaucoma affects more than 70 million people worldwide, with about 10% being bilaterally blind, making it the leading cause of irreversible blindness globally. In patients with advanced glaucoma or those who have failed medical treatment without achieving adequate intraocular pressure (IOP) control, trabeculectomy (glaucoma filtration surgery where an ostium is created into the anterior chamber from underneath a partial thickness scleral flap to allow for aqueous flow out of the anterior chamber intointo the subconjunctival space forming a filtering bleb) and aqueous shunt surgery for more complex and refractory cases remain the mainstay therapies. Proliferation of fibrous tissue around an implanted aqueous shunt may block the diffusion of aqueous humour. Read More

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http://doi.wiley.com/10.1002/14651858.CD011875.pub2
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http://dx.doi.org/10.1002/14651858.CD011875.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472957PMC
April 2019
1 Read

[Long-term Follow-up After Cryocoagulation in Preterm Newborns from Northern Greece with Retinopathy of Prematurity: Three Year Results].

Klin Monbl Augenheilkd 2019 Apr 18;236(4):542-546. Epub 2019 Apr 18.

Ophthalmologie, 2. Institut für Augenheilkunde und Ophthalmochirurgie "Ophthalmica", Thessaloniki, Griechenland.

Background: This is a retrospective study of the efficacy of treatment of neonates (NN) with exocryocoagulation retinopathy of prematurity (ROP) with respect to morphology of the retina and visual function.

Materials And Methods: Out of a total of 3103 neonates, 304 (9.8%) had a ROP. Read More

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http://dx.doi.org/10.1055/a-0880-5168DOI Listing

Exudative Retinal Detachment Following Intravitreal Chemotherapeutic Treatment for Retinoblastoma.

Ophthalmic Surg Lasers Imaging Retina 2019 Apr;50(4):248-252

A 35-month-old boy was diagnosed with retinoblastoma and underwent combination intra-arterial (IAC) and intravitreal chemotherapy. His course was complicated by anaphylactic reaction to IAC, yet he continued to improve with sustained intravitreal therapy. Eight months into treatment, the affected eye developed exudative retinal detachment, which resolved with sub-Tenon's steroid administration. Read More

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https://www.healio.com/doiresolver?doi=10.3928/23258160-2019
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http://dx.doi.org/10.3928/23258160-20190401-09DOI Listing
April 2019
4 Reads

Exudative Retinal Detachment Following Laser Photocoagulation for Retinopathy of Prematurity: A Rare Complication.

Ophthalmic Surg Lasers Imaging Retina 2019 Apr;50(4):242-246

Laser photocoagulation remains the standard of care for retinopathy of prematurity (ROP). Rarely, exudative retinal detachment (ERD) has been observed as a complication of laser treatment. The authors present the clinical course of an infant who developed severe, unilateral ERD after bilateral laser photocoagulation at 37 weeks postmenstrual age (PMA) for Type I ROP. Read More

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http://dx.doi.org/10.3928/23258160-20190401-08DOI Listing
April 2019
2 Reads

Spontaneous Hyaloidal Contraction and Complex Retinal Detachment in a Patient With Von Hippel-Lindau Syndrome.

Ophthalmic Surg Lasers Imaging Retina 2019 Apr;50(4):238-241

The authors present an interventional case report of a patient with von Hippel-Lindau (VHL) syndrome who developed simultaneous exudative and combined tractional, rhegmatogenous, and exudative retinal detachment (RD) in the right and left eyes, respectively, following uneventful cryotherapy application of retinal capillary hemangioblastoma (RCH). After pars plana vitrectomy combined with encircling scleral buckling with radial element placement and silicone oil injection, complete retinal reattachment was achieved. The exudative RD of the fellow eye was managed initially with intense topical corticosteroid treatment and subsequent placement of a radial scleral buckle due to the presence of clinically apparent traction. Read More

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http://dx.doi.org/10.3928/23258160-20190401-07DOI Listing

Long-Term Anatomic and Visual Outcome Following Vitrectomy for Stage 4B and 5 Retinopathy of Prematurity.

Ophthalmic Surg Lasers Imaging Retina 2019 Apr;50(4):208-214

Background And Objectives: Surgical indications in stages 4B and 5 retinopathy of prematurity (ROP) are not universally accepted. The authors' purpose is to evaluate the long-term anatomic and visual outcomes of vitrectomy for retinal detachment (RD) associated with stages 4B and 5 ROP.

Patients And Methods: Data of patients who consecutively underwent vitrectomy for stages 4B and 5 ROP from 1999 to 2013 were retrospectively reviewed and included grade of retinal attachment and visual acuity (VA) at the last follow-up. Read More

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http://dx.doi.org/10.3928/23258160-20190401-02DOI Listing

Early Diagnosis and Management of Aggressive Posterior Vitreoretinopathy Presenting in Premature Neonates.

Ophthalmic Surg Lasers Imaging Retina 2019 Apr;50(4):201-207

Background And Objective: Aggressive posterior vitreoretinopathy (APVR) manifests with a broad area of retinal avascularity, progressive neovascularization, and/or tractional retinal detachment during the neonatal period.

Patients And Methods: A multicenter, retrospective, observational, consecutive case series study was performed to evaluate the retinal findings and structural retinal outcomes in patients treated for APVR within the first 3 months of life.

Results: Three premature neonates with a non-retinopathy of prematurity (ROP) APVR identified during routine ROP screening exams exhibited relatively severe, rapidly progressive retinal vascular abnormalities. Read More

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https://www.healio.com/doiresolver?doi=10.3928/23258160-2019
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http://dx.doi.org/10.3928/23258160-20190401-01DOI Listing
April 2019
1 Read

Vision loss with pembrolizumab treatment: A report of two cases.

J Oncol Pharm Pract 2019 Apr 18:1078155219841683. Epub 2019 Apr 18.

University of Kansas Medical Center, Kansas City, KS.

Background: Vision loss and other ocular toxicities are rare, but detrimental, side effects of immune checkpoint inhibitors. Herein, we report two patients who developed vision loss while on pembrolizumab treatment.

Cases Presentation: Case 1 - A 58-year-old man was started on pembrolizumab for advanced melanoma. Read More

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http://dx.doi.org/10.1177/1078155219841683DOI Listing
April 2019
1 Read

[Complications in sutured scleral fixation of artificial lens implantation].

Ophthalmologe 2019 Apr 17. Epub 2019 Apr 17.

Klinik für Augenheilkunde, Universitätsmedizin Göttingen, Göttingen, Deutschland.

Background: Sutured scleral fixation of an artificial posterior chamber lens is a frequently used method for the treatment of eyes with poor or absent capsular support; however, the complication profile is often considered unfavorable.

Objective: To analyze the postoperative complication profile.

Methods: In this monocentric and retrospective analysis of a consecutive case series of patients with standardized sutured scleral fixation of a posterior chamber lens between 2007 and 2017, the documented complications were categorized as a permanent threat to visual acuity, such as endophthalmitis, choroidal hemorrhage, retinal detachment and clinically relevant but without a permanent threat to visual acuity, such as hemorrhage and hypotension. Read More

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http://link.springer.com/10.1007/s00347-019-0896-0
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http://dx.doi.org/10.1007/s00347-019-0896-0DOI Listing
April 2019
1 Read

Long-Term Intravitreal Dexamethasone Implant Outcomes in Uveitis.

Ocul Immunol Inflamm 2019 Apr 17:1-10. Epub 2019 Apr 17.

a Hospital Clinic , Institut Clínicd´Oftalmología (ICOF) , Barcelona , Spain.

Purpose: To describe the long-term clinical outcomes in a cohort of uveitic eyes treated with the intravitreal dexamethasone implant (Ozurdex; Allergan, Inc).

Methods: Seventy-nine (63 patients) receiving 134 implant injections over 82 months were included. Indication, visual acuity (VA), intraocular pressure (IOP), vitreous haze score (VHS), central retinal thickness (CRT), time to reinjection, systemic treatments, and complications data were recorded. Read More

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https://www.tandfonline.com/doi/full/10.1080/09273948.2019.1
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http://dx.doi.org/10.1080/09273948.2019.1578380DOI Listing
April 2019
1 Read

Spontaneous reattachment of total exudative retinal detachment in Coats' disease.

BMJ Case Rep 2019 Apr 14;12(4). Epub 2019 Apr 14.

Vitreoretina and Uveitis Services, L V Prasad Eye Institute, Visakhapatnam, Andhra Pradesh, India.

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http://dx.doi.org/10.1136/bcr-2019-229913DOI Listing
April 2019
1 Read

Doubles trouble-85 cases of ocular trauma in badminton: clinical features and prevention.

Br J Sports Med 2019 Apr 15. Epub 2019 Apr 15.

Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Objectives: To describe ocular injuries caused by badminton and to explore the implications for future prevention strategies.

Methods: We enrolled 85 patients with ocular trauma caused by badminton. Information collected from patients included type of game, instigator, instrument of injury and lessons in badminton from a professional, and ocular trauma information such as type of injury, treatment and final outcomes. Read More

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http://bjsm.bmj.com/lookup/doi/10.1136/bjsports-2018-099496
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http://dx.doi.org/10.1136/bjsports-2018-099496DOI Listing
April 2019
1 Read

Osteo-odonto-, Tibial bone and Boston keratoprosthesis in clinically comparable cases of chemical injury and autoimmune disease.

Ocul Surf 2019 Apr 12. Epub 2019 Apr 12.

Centro de Oftalmología Barraquer, Barcelona, Spain; Institut Universitari Barraquer, Universitat Autònoma de Barcelona, Barcelona, Spain; Universitat Internacional de Catalunya, Barcelona, Spain.

Purpose: To compare anatomical and functional results between three types of keratoprosthesis (KPro) in chemical injury and autoimmune disease.

Methods: 70 clinically comparable cases were included as follows: Boston KPro Type 1 25 eyes, osteo-odonto-keratoprosthesis (OOKP) 23 eyes, Tibial bone KPro 22 eyes. Survival times for anatomical and functional success were evaluated with Kaplan-Meier estimations and Log-rank tests. Read More

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http://dx.doi.org/10.1016/j.jtos.2019.04.006DOI Listing

Clinical predictors at diagnosis of low risk histopathology in unilateral advanced retinoblastoma.

Ophthalmology 2019 Apr 12. Epub 2019 Apr 12.

Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, Canada; Department of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria, Egypt. Electronic address:

Objective: Attempted eye salvage for unilateral (cT2b/Group D) retinoblastoma may increase risk of tumor spread compared to primary enucleation. Identification of clinical features predictive of low histopathologic risk would support safe trial salvage.

Design: Retrospective, non-comparative single-institutional observational case series PARTICIPANTS: Children with unilateral cT2b/Group D retinoblastoma (January 2008-February 2018) managed with primary enucleation at the Hospital for Sick Children (SickKids), Toronto, Canada. Read More

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http://dx.doi.org/10.1016/j.ophtha.2019.04.003DOI Listing

A novel PAX6 mutation causes congenital aniridia with or without retinal detachment.

Ophthalmic Genet 2019 Apr 15:1-4. Epub 2019 Apr 15.

c Ophthalmic Research Center , Shahid Beheshti University of Medical Sciences , Tehran , Iran.

Background: Aniridia is a rare developmental eye disorder characterized by complete or partial iris hypoplasia often accompanied with other ocular changes that affect the cornea, anterior chamber, lens, retina, and optic nerve. Most cases of aniridia are inherited with an autosomal dominant mode of inheritance caused by PAX6 mutations or deletions. To reveal the underlying genetic defect in a four-generation Iranian family with aniridia, we carried out a genetic screening of PAX6. Read More

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http://dx.doi.org/10.1080/13816810.2019.1597374DOI Listing
April 2019
1 Read

A Comparison study of Ranibizumab and Aflibercept in patients with naive diabetic macular edema in presence of serous retinal detachment.

Curr Eye Res 2019 Apr 14. Epub 2019 Apr 14.

a Bagcilar Training and Research Hospital, Ophthalmology Department , Istanbul Health Sciences University , Istanbul , TURKEY.

Aim Of The Study: The aim of this study is to compare the efficacy of intravitreal injection of Aflibercept and Ranibizumab in the treatment of naive diabetic macular edema (DME) with serous retinal detachment (SRD).

Materials And Methods: In this prospective, non- randomized-cohort study, 60 eyes with DME with SRD were divided into two groups: group1 consisted of 30 eyes treated with intravitreal injection of 0.5 mg/0. Read More

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http://dx.doi.org/10.1080/02713683.2019.1608260DOI Listing

[Treatment of retinopathy of incontinentia pigmenti by anti-vascular endothelial growth factor].

Authors:
X Wang J H Liang

Zhonghua Yan Ke Za Zhi 2019 Apr;55(4):294-301

Beijing Key Laboratory of Vision Loss and Restoration, Ministry of Education, Department of Ophthalmology, People's Hospital, Peking University, Beijing 100044, China.

To investigate the treatment of retinopathy of incontinentia pigmenti by anti-vascular endothelial growth factor. Retrospective study of 5 patients(8 eyes) diagnosed retinopathy of incontinentia pigmenti from 2005 to 2017, including 0 males and 5 females (8 eyes involved) with an average age of 2.4 months(range, 1-5 months). Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.04.012DOI Listing
April 2019
7 Reads

[The ocular manifestations of human immunodeficiency virus and syphilis coinfection].

Zhonghua Yan Ke Za Zhi 2019 Apr;55(4):267-272

Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

To investigate the ocular manifestations of human immunodeficiency virus (HIV) and syphilis coinfection. A retrospective analysis of the ocular manifestations was carried out in 27 patients (54 eyes) diagnosed as syphilis and HIV coinfection by the Department of Infectious Medicine in Peking Union Medical College Hospital during the years of 2006-2017. The research included 26 males and 1 female, aging from 24 to 76 years old, with a mean age of 40. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.04.008DOI Listing
April 2019
2 Reads

[Evaluation of the efficacy and safety of a foldable capsular vitreous body in the treatment of severe retinal detachment].

Zhonghua Yan Ke Za Zhi 2019 Apr;55(4):259-266

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Key Laboratory of intraocular Tumor Diagnosis and Treatment, Beijing 100730, China.

To determine the efficacy and safety of vitrectomy combined with implantation of a foldable capsular vitreous body in the treatment of severe retinal detachment with early ocular atrophy in human eyes. This study was a prospective, multicenter, and one-arm phase Ⅱ clinical trial. Patients with severe retinal detachment and early eyeball atrophy attending Beijing Tongren Eye Center from April 2011 to July 2012 were included. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.04.007DOI Listing

The Relative Impact of Patient, Physician, and Geographic Factors on Variation in Primary Rhegmatogenous Retinal Detachment Management.

Ophthalmology 2019 Apr 12. Epub 2019 Apr 12.

University of California San Francisco Department of Ophthalmology, San Francisco, CA, United States.

Objective: To evaluate geographic variation and characterize the relative contributions of patient characteristics, physician practice, and geographic region on variation in primary rhegmatogenous retinal detachment (RRD) management.

Design: Retrospective claims-based analysis PARTICIPANTS: 12,779 commercially-insured patients with incident RRD diagnosed between 2008 and 2016.

Methods: We determined whether patients underwent primary RRD repair within 60 days of diagnosis, and identified type of repair performed. Read More

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http://dx.doi.org/10.1016/j.ophtha.2019.04.019DOI Listing

Heterogeneity of cultured melanocyte elongation and proliferation factor in bilateral diffuse uveal melanocytic proliferation.

Exp Eye Res 2019 Apr 9. Epub 2019 Apr 9.

Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, USA. Electronic address:

A patient with bilateral diffuse uveal melanocytic proliferation (BDUMP) associated with endometrial cancer was treated with plasmapheresis, but failed therapy with progressive serous retinal detachment. We collected plasma before and after plasmapheresis therapy. Our goal was to determine if the cultured melanocyte elongation and proliferation (CMEP) factor and hepatocyte growth factor (HGF) was present in the IgG enriched fraction and understand why our patient failed plasmapheresis therapy. Read More

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http://dx.doi.org/10.1016/j.exer.2019.04.006DOI Listing

Point-of-Care Ultrasonography in the Diagnosis of Retinal Detachment, Vitreous Hemorrhage, and Vitreous Detachment in the Emergency Department.

JAMA Netw Open 2019 Apr 5;2(4):e192162. Epub 2019 Apr 5.

Department of Emergency Medicine, University of California, Irvine.

Importance: Ocular symptoms represent approximately 2% to 3% of all emergency department (ED) visits. These disease processes may progress to permanent vision loss if not diagnosed and treated quickly. Use of ocular point-of-care ultrasonography (POCUS) may be effective for early and accurate detection of ocular disease. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2019.2162DOI Listing

The First Multicenter Evidence for Ocular Point-of-Care Ultrasonography for Retinal Detachment by Emergency Physicians.

Authors:
John Bailitz

JAMA Netw Open 2019 Apr 5;2(4):e192148. Epub 2019 Apr 5.

Northwestern University Emergency Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.2148DOI Listing

Spontaneous resolution of myopic retinoschisis.

AME Case Rep 2019 13;3. Epub 2019 Feb 13.

Ophthalmology Department, Hong Kong Adventist Hospital, Hong Kong, China.

Spontaneous resolution of myopic retinoschisis is an unusual event due to the fact that most eyes of patients with this condition have already undergone certain morphological changes and vision will progressively worsen over time. We present a case of spontaneous anatomic and visual improvement in a myopic eye with a macular retinoschisis. The patient was monocular oculus dextrus (OD) with a history of left eye enucleation for recurrent retinal detachment and glaucoma for 30 years prior. Read More

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http://dx.doi.org/10.21037/acr.2019.01.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414358PMC
February 2019

Polypoidal Choroidal Vasculopathy.

Curr Ophthalmol Rep 2019 Mar 2;7(1):66-72. Epub 2019 Feb 2.

Marina del Rey, CA.

Purpose Of Review: The aim of this review is to summarize developments in the treatment of active polypoidal choroidal vasculopathy (PCV). PCV is associated with a poor visual prognosis as a consequence the condition's hallmark polypoidal dilatation and a branching network resulting in recurrent hemorrhages and serous leakage.

Recent Findings: Recent research has provided new insights into the pathogenesis of PCV. Read More

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http://dx.doi.org/10.1007/s40135-019-00201-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453130PMC

Optimizing optical coherence tomography and histopathology correlation in retinal imaging.

Can J Ophthalmol 2019 Apr 27;54(2):280-287. Epub 2018 Aug 27.

Pathology Department, McGill University, Montreal, Que., Canada; Ophthalmology Department, Federal University of São Paulo, São Paulo, Brazil.

Objective: To develop a methodology to correlate optical coherence tomography (OCT) images and histopathological sections from the same eye. Part 1: To determine the best fixative for optimal OCT and histopathological analysis in post-mortem eyes. Part 2: A protocol is proposed to correlate histopathological features and OCT scans from the same post-mortem eyes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00084182183057
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http://dx.doi.org/10.1016/j.jcjo.2018.06.024DOI Listing
April 2019
2 Reads
1.299 Impact Factor

Outcomes of 25-gauge vitrectomy with relaxing retinectomy for retinal detachment secondary to proliferative vitreoretinopathy.

J Vitreoretin Dis 2019 Mar 26;3(2):69-75. Epub 2019 Feb 26.

Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA.

Purpose: The aim of this study is to evaluate visual and anatomic outcomes of 25-gauge vitrectomy with relaxing retinectomies for complex retinal detachment (RD) secondary to proliferative vitreoretinopathy (PVR).

Methods: A single-center, retrospective case series of 44 patients who had undergone a 25-gauge vitrectomy with a relaxing retinectomy for the treatment of combined RD and PVR was performed. Pre-operative characteristics, intraoperative techniques, and outcomes were analyzed. Read More

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http://dx.doi.org/10.1177/2474126419831614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453131PMC

Intravitreal neurodegenerative and inflammatory mediators in proliferative diabetic retinopathy.

Arq Bras Oftalmol 2019 Apr 8. Epub 2019 Apr 8.

Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

Purpose: To compare the intravitreal concentrations of cellular mediators involved in neurodegeneration, inflammation, and angiogenesis in patients with proliferative diabetic retinopathy and other vitreoretinal diseases.

Methods: A multiplex bead immunoassay was used to measure vitreous levels of pigment epithelium-derived factor, serum amyloid P, C-reactive protein, complement C4, alpha-1 antitrypsin, vascular endothelial growth factor, platelet-derived growth factor-AA, platelet-derived growth factor-BB, interleukin-6, interleukin-8, interleukin-10, tumor necrosis factor alpha and beta in patients undergoing 23-gauge vitrectomy for proliferative diabetic retinopathy and other diagnoses (control group).

Results: We evaluated 55 patients, of whom 24 had proliferative diabetic retinopathy and 31 had other diagnoses including vitreous hemorrhage, retinal detachment, macular hole, and epiretinal membrane. Read More

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http://dx.doi.org/10.5935/0004-2749.20190055DOI Listing
April 2019
1 Read

Diffractive trifocal pseudophakic intraocular lenses in high myopic eyes: 2-year assessment after implantation.

Graefes Arch Clin Exp Ophthalmol 2019 Apr 9. Epub 2019 Apr 9.

Department of Refractive Surgery, Clínica Baviera Castellón, Castellón, Spain.

Purpose: To assess the visual outcomes and ocular safety when implanting diffractive trifocal intraocular lenses in a population of high myopic eyes.

Methods: This is a retrospective cumulative clinical study. Two hundred five myopic eyes consecutively operated in the hospitals of Clínica Baviera, Spain, were included. Read More

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http://dx.doi.org/10.1007/s00417-019-04302-5DOI Listing
April 2019
1 Read

EPIRETINAL MEMBRANE IN EYES WITH VITREOMACULAR TRACTION.

Retina 2019 Apr 4. Epub 2019 Apr 4.

Ophthalmology Clinic, University of Bristol, Bristol, United Kingdom.

Purpose: To describe the occurrence of epiretinal membrane (ERM) in eyes with vitreomacular traction and to correlate the presence of ERM with retinal structural alterations detected using spectral domain optical coherence tomography.

Methods: In this retrospective observational cross-sectional study, we collected data from 502 eyes (307 patients) with diagnosis of vitreomacular traction. The presence of ERM and retinal lesions (cystoid cavities, neuroepithelial detachment, external limiting membrane, and ellipsoid zone discontinuity) was determined by standardized grading of macular spectral domain optical coherence tomography scans. Read More

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http://Insights.ovid.com/crossref?an=00006982-900000000-9615
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http://dx.doi.org/10.1097/IAE.0000000000002546DOI Listing
April 2019
1 Read

Prevalence and Associations of Posterior Segment Manifestations in a Cohort of Egyptian Patients with Pathological Myopia.

Curr Eye Res 2019 Apr 9. Epub 2019 Apr 9.

a Department of Ophthalmology, Faculty of Medicine , Cairo University , Cairo , Egypt.

Purpose: To determine the prevalence of posterior segment manifestations among consecutive patients with pathological myopia attending our University Hospital general ophthalmology clinic and their association with age, refractive error, axial length and each other.

Methods: Patients diagnosed with pathological myopia underwent full ophthalmological examination, optical coherence tomography, fluorescein angiography, and ocular ultrasonography. Manifestations detected were recorded for each eye and their prevalence and association with age, refractive error, axial length and each other was determined. Read More

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http://dx.doi.org/10.1080/02713683.2019.1606252DOI Listing
April 2019
1 Read

Retinal-detachment repair and vitreous-like-body reformation via a thermogelling polymer endotamponade.

Nat Biomed Eng 2019 Apr 8. Epub 2019 Apr 8.

Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Internal-tamponade agents are crucial surgical adjuncts in vitreoretinal surgery. Clinically used endotamponade agents act through buoyancy forces, yet can result in prolonged post-operative positioning, temporary loss of vision, raised intra-ocular pressure, cataract formation or the need for additional removal surgery. Here, we describe a thermogelling polymer that provides an internal tamponade effect through surface tension and swelling counter-forces. Read More

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http://dx.doi.org/10.1038/s41551-019-0382-7DOI Listing

Long-term Clinical Results of Vitrectomy and Scleral Buckling in Treatment of Rhegmatogenous Retinal Detachment.

ScientificWorldJournal 2019 6;2019:5416806. Epub 2019 Mar 6.

Department of Ophthalmology, RWTH Aachen University, Aachen, Germany.

Purpose: Most studies about retinal detachment cover a limited follow-up period. The purpose of this research is to assess the long-term results after pars plana vitrectomy (PPV) and scleral buckle (SB) surgery in patients with rhegmatogenous retinal detachment (RRD).

Methods: 155 patients with RRD are treated either with SB or PPV with a mean follow-up of more than 5 years. Read More

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https://www.hindawi.com/journals/tswj/2019/5416806/
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http://dx.doi.org/10.1155/2019/5416806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431356PMC
March 2019
3 Reads

Posterior persistent fetal vasculature associated with tractional retinal detachment.

J Fr Ophtalmol 2019 Apr 4. Epub 2019 Apr 4.

Departement A of ophthalmology, university Mohamed V Souissi, 6203 Rabat, Morocco.

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http://dx.doi.org/10.1016/j.jfo.2018.11.010DOI Listing

A human amniotic membrane plug to repair retinal detachment associated with large macular tear.

Acta Ophthalmol 2019 Apr 6. Epub 2019 Apr 6.

Department of Translational Surgery and Medicine, Ophthalmology, University of Florence, Careggi, Florence, Italy.

Purpose: To describe a surgical technique, using a human amniotic membrane (hAM) plug, in two cases of retinal detachment with a large macular tear.

Methods: Surgical technique description with surgical video. A 23-gauge pars plana vitrectomy with peripheral retinectomy was performed. Read More

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http://dx.doi.org/10.1111/aos.14109DOI Listing
April 2019
1 Read

Long-term outcomes of patients with myopic traction maculopathy after phacoemulsification for incident cataract.

Eye (Lond) 2019 Apr 5. Epub 2019 Apr 5.

Department of Ophthalmology, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, 200031, Shanghai, China.

Purpose: To evaluate the long-term effect of cataract surgery on highly myopic patients with myopic traction maculopathy (MTM) and the risk factors associated with MTM progression.

Methods: Highly myopic patients with cataract and MTM were included. Phacoemulsification surgery was performed on patients who had vision loss below 20/63 and were willing to operation. Read More

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http://dx.doi.org/10.1038/s41433-019-0416-0DOI Listing
April 2019
3 Reads

Early Buckle Migration and Restrictive Strabismus after Successful Medical Management of Scleral Buckle Infection.

J Binocul Vis Ocul Motil 2019 Apr 5:1-3. Epub 2019 Apr 5.

c Department of Comprehensive Ophthalmology , Aravind Eye Hospital , Pondicherry , India.

We report a case of restrictive strabismus caused by early scleral buckle (SB) migration within 1 month of surgery after successful medical management of SB infection. A 24 year-old man underwent scleral buckling surgery for left eye inferior retinal detachment (RD). A solid silicone buckle element was placed inferiorly along with an encircling silicone band. Read More

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http://dx.doi.org/10.1080/2576117X.2019.1590140DOI Listing
April 2019
2 Reads

COMPARISON OF INTRAVITREAL DEXAMETHASONE IMPLANT AND AFLIBERCEPT IN PATIENTS WITH TREATMENT-NAIVE DIABETIC MACULAR EDEMA WITH SEROUS RETINAL DETACHMENT.

Retina 2019 Apr 2. Epub 2019 Apr 2.

Kayseri City Hospital, Kocasinan, Kayseri, Turkey.

Purpose: To compare the efficacy and safety of intravitreal dexamethasone (DEX) implant versus aflibercept in patients with treatment-naive diabetic macular edema with inflammatory biomarkers.

Methods: Ninety-eight eyes of 62 treatment-naive patients with diabetic macular edema with serous retinal detachment and hyperreflective foci were enrolled. Each patient was randomized to receive either aflibercept or DEX implant treatment. Read More

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http://Insights.ovid.com/crossref?an=00006982-900000000-9616
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http://dx.doi.org/10.1097/IAE.0000000000002537DOI Listing
April 2019
2 Reads

Adjunctive dexamethasone implant in patients with atopic dermatitis and retinal detachment undergoing vitrectomy and silicone oil tamponade: an interventional case series.

BMC Ophthalmol 2019 Apr 3;19(1):86. Epub 2019 Apr 3.

Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, 88, Olympic-ro 43-Gil, Songpa-gu, Seoul, 05505, Korea.

Background: To report the clinical course and outcomes of adjunctive dexamethasone implants in patients with atopic dermatitis (AD) and retinal detachment (RD) undergoing vitrectomy and silicone oil tamponade.

Methods: This retrospective, interventional case series included AD patients with RD and various degrees of proliferative vitreoretinopathy (PVR) who were scheduled to undergo vitrectomy. Following total vitrectomy and retinopexy, silicone oil tamponade was performed. Read More

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http://dx.doi.org/10.1186/s12886-019-1094-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448232PMC
April 2019
2 Reads
1.075 Impact Factor

Biomarkers for PVR in rhegmatogenous retinal detachment.

PLoS One 2019 3;14(4):e0214674. Epub 2019 Apr 3.

Swiss Eye Institute and Clinic for Vitreoretinal Diseases, Berner Augenklinik am Lindenhof-Spital, Bern, Switzerland.

Purpose: Various profibrotic and proinflammatory cytokines have been found upregulated in uncomplicated primary retinal detachment (pRD), but without providing a uniform picture. Here, we compare the cyto- and chemokine profiles in pRD with and without proliferative vitreoretinopathy (PVR) in an attempt to unravel relevant differences not in single cytokines, but in the cytokine profiles at diagnosis.

Methods: Undiluted vitreous fluid (VF) was obtained at the beginning of surgery from 174 eyes with pRD without relevant PVR (maximally grade B; group 1; n = 81) and with moderate or advanced PVR requiring a gas tamponade (group 2; n = 49) or silicon oil filling (group 3; n = 44). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214674PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447182PMC
April 2019
3 Reads

The Effect of Compliance With Preoperative Posturing Advice and Head Movements on the Progression of Macula-On Retinal Detachment.

Transl Vis Sci Technol 2019 Mar 26;8(2). Epub 2019 Mar 26.

Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands.

Purpose: The aim of this study was to explore the relationship between compliance with preoperative posturing advice and progression of macula-on retinal detachment (RD) and to evaluate whether head positioning or head motility contributes most to RD progression.

Methods: Sixteen patients with macula-on RD were enrolled, admitted to the ward, and instructed to posture preoperatively. The primary outcome parameter was compliance, which was defined as the average head orientation deviation from advised positioning. Read More

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http://dx.doi.org/10.1167/tvst.8.2.4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438104PMC

The effect of single periocular injection of methylprednisolone and drainage of suprachoroidal fluid in the treatment of rhegmatogenous retinal detachment combined with choroidal detachment.

Eye (Lond) 2019 Apr 2. Epub 2019 Apr 2.

The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.

Purpose: In this study we compared the anatomic and functional outcomes of two steroid treatments on rhegmatogenous retinal detachment (RRD) combined with choroidal detachment (CD), namely treatment with oral prednisolone (1 mg/kg daily) for 3-7 days before vitrectomy or a single periocular injection of methylprednisolone (40 mg) 1-3 days before vitrectomy. We also analyzed the outcomes of the eyes with subsided CD and the eyes with persistent CD that underwent drainage of suprachoroidal fluids during the vitrectomy.

Methods: This was a prospective randomized study. Read More

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http://dx.doi.org/10.1038/s41433-019-0420-4DOI Listing

Ocular bleeding in an undiagnosed hemophiliac neonate causing irreversible loss of vision: A case report with review of the literature.

Eur J Ophthalmol 2019 Apr 2:1120672119841188. Epub 2019 Apr 2.

1 Department of Ophthalmology, King Abdul-Aziz University Hospital, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Introduction:: Suprachoroidal hemorrhage is an unexpected complication after penetrating keratoplasty during childhood. We report the case of delayed suprachoroidal hemorrhage after penetrating keratoplasty in a neonate as the first manifestation of hemophilia.

Case Report:: A 4-day-old neonate was referred to our hospital because of bilateral corneal opacities present since birth. Read More

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http://journals.sagepub.com/doi/10.1177/1120672119841188
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http://dx.doi.org/10.1177/1120672119841188DOI Listing
April 2019
3 Reads

[Congenital abnormalities of the optic disc].

J Fr Ophtalmol 2019 Mar 29. Epub 2019 Mar 29.

Hôtel-Dieu, 1 place Alexis-Ricordeau, 44000 Nantes, France.

Congenital abnormalities of the optic disc are not uncommon in clinical practice and should be recognized. Size abnormalities of the optic disc include optic disc aplasia, hypoplasia, megalopapilla, and optic disc cupping in prematurity. Among congenital excavations of the optic disc head, morning glory disc anomaly and optic disc pit can be complicated by serous retinal detachment; the papillorenal disc is an association of bilateral optic disc cupping and renal hypoplasia which should be ruled out; optic disc coloboma is caused by an abnormal closure of the embryonic fissure and can be complicated by choroidal neovascularization and retinal detachment. Read More

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http://dx.doi.org/10.1016/j.jfo.2018.09.011DOI Listing

The Natural History of Congenital X-Linked Retinoschisis and Conversion between Phenotypes over Time.

Ophthalmol Retina 2019 Jan 24;3(1):77-82. Epub 2018 Aug 24.

Associated Retinal Consultants, William Beaumont Hospital, Royal Oak, Michigan; William Beaumont School of Medicine, Oakland University, Rochester, Michigan. Electronic address:

Purpose: To evaluate the natural history of congenital X-linked retinoschisis (CXLRS) and to assess disease stability or progression over time.

Design: Retrospective case series at a single-center, tertiary care, pediatric retina practice.

Participants: One hundred two eyes of 51 patients with CXLRS. Read More

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http://dx.doi.org/10.1016/j.oret.2018.08.006DOI Listing
January 2019

New Scleral Depressor Marker for Retinal Detachment Surgery.

Ophthalmol Retina 2019 Jan 22;3(1):73-76. Epub 2018 Aug 22.

Department of Ophthalmology, Rudolf Foundation Hospital, Vienna, Austria; Karl Landsteiner Institute for Retinal Research and Imaging, Vienna, Austria; Eye Center Donaustadt, Sigmund Freud University, Vienna, Austria.

Purpose: To report the efficacy of the use of a new scleral depressor marker during scleral buckling surgery for retinal detachment.

Design: Noncomparative, consecutive case series study.

Participants: Eleven patients (11 eyes) with rhegmatogenous retinal detachment who underwent scleral buckling surgery performed by 2 experienced vitreoretinal surgeons. Read More

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http://dx.doi.org/10.1016/j.oret.2018.08.005DOI Listing
January 2019
2 Reads

Traumatic Maculopathy with Massive Subretinal Hemorrhage after Closed-Globe Injuries: Associated Findings, Management, and Visual Outcomes.

Ophthalmol Retina 2019 Jan 25;3(1):53-60. Epub 2018 Aug 25.

Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan.

Purpose: To investigate the visual outcomes of patients with traumatic maculopathy and massive subretinal hemorrhage (SRH) after closed-globe injury.

Design: Retrospective, noncomparative, and interventional case series.

Participants: Twenty-four patients with traumatic maculopathy and massive SRH after closed-globe injury. Read More

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http://dx.doi.org/10.1016/j.oret.2018.08.007DOI Listing
January 2019
2 Reads