22,353 results match your criteria Retinal Cases & Brief Reports [Journal]


Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma.

Cochrane Database Syst Rev 2019 Apr 19;4:CD011875. Epub 2019 Apr 19.

Ophthalmology, Singapore National Eye Centre, Singapore, Singapore.

Background: Glaucoma affects more than 70 million people worldwide, with about 10% being bilaterally blind, making it the leading cause of irreversible blindness globally. In patients with advanced glaucoma or those who have failed medical treatment without achieving adequate intraocular pressure (IOP) control, trabeculectomy (glaucoma filtration surgery where an ostium is created into the anterior chamber from underneath a partial thickness scleral flap to allow for aqueous flow out of the anterior chamber intointo the subconjunctival space forming a filtering bleb) and aqueous shunt surgery for more complex and refractory cases remain the mainstay therapies. Proliferation of fibrous tissue around an implanted aqueous shunt may block the diffusion of aqueous humour. Read More

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http://doi.wiley.com/10.1002/14651858.CD011875.pub2
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http://dx.doi.org/10.1002/14651858.CD011875.pub2DOI Listing
April 2019
1 Read

[Ocular Syphilis May Lead to Persistent Visual Dysfunction].

Klin Monbl Augenheilkd 2019 Apr 18;236(4):516-522. Epub 2019 Apr 18.

Augenklinik, UniversitätsSpital Zürich, Universität Zürich, Schweiz.

Purpose: The spectrum of intraocular and systemic findings in patients with ocular syphilis is described. Persistent visual dysfunction and structural abnormality, in spite of targeted antibiotic therapy, were identified and analysed.

Methods: Patients with ocular syphilis who were treated at University Hospital Zurich (USZ) between 2010 and 2018 were included in this study. Read More

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http://dx.doi.org/10.1055/a-0854-3421DOI Listing

Long-Term Course Following Vitreous Surgery for Epiretinal Membrane.

Ophthalmic Surg Lasers Imaging Retina 2019 Apr;50(4):e105-e111

Background And Objective: To follow the long-term course of visual acuity (VA) and central retinal thickness (CRT) over at least a 3-year follow-up after vitreous surgery in patients with epiretinal membrane (ERM).

Patients And Methods: This study examined 43 eyes of patients who underwent 23- or 25-gauge vitreous surgery for ERM.

Results: There was significant improvement of the VA at 3 months after surgery compared with baseline, with the improvements maintained for 5 years (analysis of variance [ANOVA]; P < . Read More

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https://www.healio.com/doiresolver?doi=10.3928/23258160-2019
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http://dx.doi.org/10.3928/23258160-20190401-14DOI Listing
April 2019
1 Read

Early Diagnosis and Management of Aggressive Posterior Vitreoretinopathy Presenting in Premature Neonates.

Ophthalmic Surg Lasers Imaging Retina 2019 Apr;50(4):201-207

Background And Objective: Aggressive posterior vitreoretinopathy (APVR) manifests with a broad area of retinal avascularity, progressive neovascularization, and/or tractional retinal detachment during the neonatal period.

Patients And Methods: A multicenter, retrospective, observational, consecutive case series study was performed to evaluate the retinal findings and structural retinal outcomes in patients treated for APVR within the first 3 months of life.

Results: Three premature neonates with a non-retinopathy of prematurity (ROP) APVR identified during routine ROP screening exams exhibited relatively severe, rapidly progressive retinal vascular abnormalities. Read More

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https://www.healio.com/doiresolver?doi=10.3928/23258160-2019
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http://dx.doi.org/10.3928/23258160-20190401-01DOI Listing
April 2019
1 Read

Vision loss with pembrolizumab treatment: A report of two cases.

J Oncol Pharm Pract 2019 Apr 18:1078155219841683. Epub 2019 Apr 18.

University of Kansas Medical Center, Kansas City, KS.

Background: Vision loss and other ocular toxicities are rare, but detrimental, side effects of immune checkpoint inhibitors. Herein, we report two patients who developed vision loss while on pembrolizumab treatment.

Cases Presentation: Case 1 - A 58-year-old man was started on pembrolizumab for advanced melanoma. Read More

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http://dx.doi.org/10.1177/1078155219841683DOI Listing
April 2019
1 Read

Estimating the magnitude of diabetes mellitus and diabetic retinopathy in an older age urban population in Pune, western India.

BMJ Open Ophthalmol 2019 28;4(1):e000201. Epub 2019 Feb 28.

Department of Community Ophthalmology, PBMA's H. V. Desai Eye Hospital, Pune, Maharashtra, India.

Objective: To estimate magnitude of diabetes mellitus (DM) and diabetic retinopathy (DR) in a high risk population in Pune, western India.

Methods: DR module in rapid assessment of avoidable blindness (RAAB) survey methodology was used. Sample size of 3527 was calculated based on estimates from previous studies in India. Read More

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http://dx.doi.org/10.1136/bmjophth-2018-000201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440599PMC
February 2019

Intravitreal Ranibizumab Injection for the Treatment of Retinopathy of Prematurity.

Med Princ Pract 2019 Apr 16. Epub 2019 Apr 16.

Objectives: To evaluate the efficacy of a single injection of 0.3 mg of intravitreal ranibizumab for the treatment of retinopathy of prematurity.

Methods: We conducted this retrospective case series study in King Abdul Aziz Medical City, Riyadh, Saudi Arabia. Read More

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http://dx.doi.org/10.1159/000500310DOI Listing
April 2019
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Longitudinal Assessment of Rod Function in Intermediate Age-Related Macular Degeneration With and Without Reticular Pseudodrusen.

Invest Ophthalmol Vis Sci 2019 Apr;60(5):1511-1518

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Australia.

Purpose: To evaluate rod function longitudinally in intermediate age-related macular degeneration subjects with reticular pseudodrusen (RPD) and without RPD (AMD).

Methods: Retinal sensitivities (505 and 625 nm) during dark adaptation, at 14 locations within the central 12° macula were obtained after photobleaching at baseline and 12-month visits. Pointwise sensitivity differences between both stimuli were used to assess static rod function, while rod intercept time (RIT) and rod recovery rate (RRR) were used to evaluate dynamic function. Read More

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http://dx.doi.org/10.1167/iovs.18-26385DOI Listing

The Relation of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio with High Axial Myopia.

Ocul Immunol Inflamm 2019 Apr 17:1-6. Epub 2019 Apr 17.

b Faculty of Medicine, Department of Ophthalmology , Karadeniz Technical University , Trabzon , Turkey.

Purpose: To investigate the relation between high axial myopia and neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) values.

Methods: Seventy-nine cases were enrolled, 50 myopic and 29 emmetropic. All participants were assigned into three groups: Group I (high myopia with no retinal involvement), Group II (high myopia with retinal involvement) and Group III (control). Read More

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http://dx.doi.org/10.1080/09273948.2019.1588334DOI Listing

Long-Term Intravitreal Dexamethasone Implant Outcomes in Uveitis.

Ocul Immunol Inflamm 2019 Apr 17:1-10. Epub 2019 Apr 17.

a Hospital Clinic , Institut Clínicd´Oftalmología (ICOF) , Barcelona , Spain.

Purpose: To describe the long-term clinical outcomes in a cohort of uveitic eyes treated with the intravitreal dexamethasone implant (Ozurdex; Allergan, Inc).

Methods: Seventy-nine (63 patients) receiving 134 implant injections over 82 months were included. Indication, visual acuity (VA), intraocular pressure (IOP), vitreous haze score (VHS), central retinal thickness (CRT), time to reinjection, systemic treatments, and complications data were recorded. Read More

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http://dx.doi.org/10.1080/09273948.2019.1578380DOI Listing

Impact of optical coherence tomography on diagnostic decision-making by UK community optometrists: a clinical vignette study.

Ophthalmic Physiol Opt 2019 May;39(3):205-215

Division of Optometry and Visual Science, City University of London, London, UK.

Purpose: In recent years, there has been widespread investment in imaging technologies by community optometrists in the UK, most notably optical coherence tomography (OCT). The aim of the current study was to determine the value of OCT in the diagnosis of posterior segment diseases in a representative sample of community optometrists using a clinical vignette methodology.

Methods: A group of community optometrists (n = 50) initially completed a standardised training package on OCT interpretation followed by a computer-based assessment featuring 52 clinical vignettes, containing images of healthy (n = 8) or glaucomatous (n = 18) discs or healthy (n = 8) or diseased (n = 18) fundi. Read More

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http://dx.doi.org/10.1111/opo.12613DOI Listing

FUNDUS AUTOFLUORESCENCE PREDICTING GROWTH OF A CHOROIDAL OSTEOMA IN A 13-YEAR-OLD GIRL.

Retin Cases Brief Rep 2019 Apr 10. Epub 2019 Apr 10.

Department of Ophthalmology, Henry Ford Health System, Detroit, Michigan.

Purpose: To describe multimodal imaging findings, including fundus autofluorescence, in a patient with a growing choroidal osteoma.

Methods: Case report.

Results: A 13-year-old girl presented with an asymptomatic lesion in the superonasal macula of her left eye. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000874DOI Listing
April 2019
1 Read

Doubles trouble-85 cases of ocular trauma in badminton: clinical features and prevention.

Br J Sports Med 2019 Apr 15. Epub 2019 Apr 15.

Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Objectives: To describe ocular injuries caused by badminton and to explore the implications for future prevention strategies.

Methods: We enrolled 85 patients with ocular trauma caused by badminton. Information collected from patients included type of game, instigator, instrument of injury and lessons in badminton from a professional, and ocular trauma information such as type of injury, treatment and final outcomes. Read More

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http://bjsm.bmj.com/lookup/doi/10.1136/bjsports-2018-099496
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http://dx.doi.org/10.1136/bjsports-2018-099496DOI Listing
April 2019
1 Read

COMBINED PHACOEMULSIFICATION SURGERY WITH MULTIFOCAL INTRAOCULAR LENS IMPLANTATION AND PARS PLANA VITRECTOMY FOR SYMPTOMATIC VITREOUS OPACITIES.

Retin Cases Brief Rep 2019 Apr 8. Epub 2019 Apr 8.

Cincinnati Eye Institute, Cincinnati, OH.

Purpose: To report surgical outcomes of combined vitrectomy for vitreous floaters and phacoemulsification surgery with multifocal intraocular lens implantation.

Methods: Retrospective, interventional, noncomparative case series of five eyes from five patients who underwent same-day combined phacoemulsification surgeries with apodized, diffractive multifocal intraocular lens implantation for cataract and pars plana vitrectomy for symptomatic vitreous opacities, that is, floaters. Primary outcomes were distance and near visual acuities, and resolution of symptoms. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000873DOI Listing

Osteo-odonto-, Tibial bone and Boston keratoprosthesis in clinically comparable cases of chemical injury and autoimmune disease.

Ocul Surf 2019 Apr 12. Epub 2019 Apr 12.

Centro de Oftalmología Barraquer, Barcelona, Spain; Institut Universitari Barraquer, Universitat Autònoma de Barcelona, Barcelona, Spain; Universitat Internacional de Catalunya, Barcelona, Spain.

Purpose: To compare anatomical and functional results between three types of keratoprosthesis (KPro) in chemical injury and autoimmune disease.

Methods: 70 clinically comparable cases were included as follows: Boston KPro Type 1 25 eyes, osteo-odonto-keratoprosthesis (OOKP) 23 eyes, Tibial bone KPro 22 eyes. Survival times for anatomical and functional success were evaluated with Kaplan-Meier estimations and Log-rank tests. Read More

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http://dx.doi.org/10.1016/j.jtos.2019.04.006DOI Listing

A novel PAX6 mutation causes congenital aniridia with or without retinal detachment.

Ophthalmic Genet 2019 Apr 15:1-4. Epub 2019 Apr 15.

c Ophthalmic Research Center , Shahid Beheshti University of Medical Sciences , Tehran , Iran.

Background: Aniridia is a rare developmental eye disorder characterized by complete or partial iris hypoplasia often accompanied with other ocular changes that affect the cornea, anterior chamber, lens, retina, and optic nerve. Most cases of aniridia are inherited with an autosomal dominant mode of inheritance caused by PAX6 mutations or deletions. To reveal the underlying genetic defect in a four-generation Iranian family with aniridia, we carried out a genetic screening of PAX6. Read More

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http://dx.doi.org/10.1080/13816810.2019.1597374DOI Listing
April 2019
1 Read

Cyclosporine and prednisolone combination therapy as a potential therapeutic strategy for relentless placoid chorioretinitis.

Am J Ophthalmol Case Rep 2019 Jun 23;14:87-91. Epub 2019 Mar 23.

Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Purpose: Relentless placoid chorioretinitis (RPC) is a new disease concept that was proposed by Jones et al. in 2000. Some cases of RPC have been reported; however, a treatment strategy has not yet been established. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444293PMC

A Comparison study of Ranibizumab and Aflibercept in patients with naive diabetic macular edema in presence of serous retinal detachment.

Curr Eye Res 2019 Apr 14. Epub 2019 Apr 14.

a Bagcilar Training and Research Hospital, Ophthalmology Department , Istanbul Health Sciences University , Istanbul , TURKEY.

Aim Of The Study: The aim of this study is to compare the efficacy of intravitreal injection of Aflibercept and Ranibizumab in the treatment of naive diabetic macular edema (DME) with serous retinal detachment (SRD).

Materials And Methods: In this prospective, non- randomized-cohort study, 60 eyes with DME with SRD were divided into two groups: group1 consisted of 30 eyes treated with intravitreal injection of 0.5 mg/0. Read More

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http://dx.doi.org/10.1080/02713683.2019.1608260DOI Listing

[Child photophobia].

Rev Prat 2019 Feb;69(2):183-187

Service d'exploration de la vision et de neuro-ophtalmologie, hôpital Roger- Salengro, CHRU de Lille, Lille, France.

Child photophobia. Photophobia is abnormal intolerance of light. It is a commonest complaint and a reason for ophthalmological assessment in adults. Read More

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February 2019
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[Treatment of retinopathy of incontinentia pigmenti by anti-vascular endothelial growth factor].

Authors:
X Wang J H Liang

Zhonghua Yan Ke Za Zhi 2019 Apr;55(4):294-301

Beijing Key Laboratory of Vision Loss and Restoration, Ministry of Education, Department of Ophthalmology, People's Hospital, Peking University, Beijing 100044, China.

To investigate the treatment of retinopathy of incontinentia pigmenti by anti-vascular endothelial growth factor. Retrospective study of 5 patients(8 eyes) diagnosed retinopathy of incontinentia pigmenti from 2005 to 2017, including 0 males and 5 females (8 eyes involved) with an average age of 2.4 months(range, 1-5 months). Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.04.012DOI Listing
April 2019
6 Reads

Evaluation of amalgam-related retinal neurotoxicity with optical coherence tomography findings.

Hum Exp Toxicol 2019 Apr 12:960327119842637. Epub 2019 Apr 12.

1 Department of Ophthalmology, School of Medicine, Adıyaman University, Adıyaman, Turkey.

Purpose: To evaluate the neurotoxic effect of amalgam dental fillings on plasma mercury (Hg) levels and retino-choroidal layers measured by spectral domain optical coherence tomography (SD-OCT).

Materials/methods: Study participants included 56 cases with amalgam dental fillings and 44 healthy controls. All participants were examined in terms of detailed ophthalmic examination, oral examination, and body mass index (BMI). Read More

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http://dx.doi.org/10.1177/0960327119842637DOI Listing

Epiretinal Proliferation Associated with Lamellar Hole or Macular Hole: Origin and Surgical Prognosis.

Korean J Ophthalmol 2019 Apr;33(2):142-149

Department of Ophthalmology, HanGil Eye Hospital, Incheon, Korea.

Purpose: To determine the origin of epiretinal proliferation (EP), a condition that is occasionally observed in lamellar hole and macular hole cases, and EP outcomes after vitrectomy.

Methods: This is a retrospective observational case review of 17 eyes with EP that underwent vitrectomy, EP dissection, and internal limiting membrane peeling between January 2013 and December 2016. Surgical specimens of EP tissue were successfully obtained from 5 cases and they were analyzed after immunohistochemical staining. Read More

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http://dx.doi.org/10.3341/kjo.2018.0070DOI Listing

Genetic testing in patients with retinitis pigmentosa: features of unsolved cases.

Clin Exp Ophthalmol 2019 Apr 11. Epub 2019 Apr 11.

Department of Ophthalmology, University of Bonn, Bonn, Germany.

Importance: Uncommon characteristics in genetically unsolved retinitis pigmentosa (RP) patients may indicate an incorrect clinical diagnosis or as yet unknown genetic causes resulting in specific retinal phenotypes. The diagnostic yield of targeted next-generation sequencing may be increased by a reasonable preselection of RP-patients.

Background: To systematically evaluate and compare features of genetically solved and unsolved RP-patients. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ceo.13516
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http://dx.doi.org/10.1111/ceo.13516DOI Listing
April 2019
3 Reads

Metastatic Cutaneous Melanoma Presenting with Choroidal Metastasis Simulating Primary Uveal Melanoma.

Ocul Oncol Pathol 2019 Feb 8;5(2):135-138. Epub 2018 Aug 8.

Department of Ophthalmology, University of California, San Francisco, California, USA.

Purpose: To report a case of metastatic cutaneous melanoma presenting with choroidal metastasis simulating primary uveal melanoma.

Design: Case report.

Method: Presentation of clinical, radiographic, histopathologic, and tumor genetic findings in a patient with cutaneous melanoma with choroidal metastasis. Read More

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https://www.karger.com/Article/FullText/488708
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http://dx.doi.org/10.1159/000488708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422132PMC
February 2019
4 Reads

Mean platelet volume and central retinal vein occlusion in hypertensive patients.

Can J Ophthalmol 2019 Apr 22;54(2):275-279. Epub 2018 Jun 22.

Department of Vitreo-Retina Surgery, Grant Medical College and Sir J. J. Group of Hospitals, Mumbai, India.

Objective: To study the relationship between mean platelet volume (MPV) and central retinal vein occlusion (CRVO) in hypertensive patients.

Design: Hospital-based, retrospective, case control design.

Participants: The sample group consisted of 100 patients with a known history of hypertension and who are diagnosed with CRVO. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00084182183019
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http://dx.doi.org/10.1016/j.jcjo.2018.04.014DOI Listing
April 2019
1 Read
1.299 Impact Factor

Evaluation of dynamic thiol-disulfide homeostasis in glaucoma patients and the correlation with retinal nerve fiber layer analysis.

Eur J Ophthalmol 2019 Apr 12:1120672119839582. Epub 2019 Apr 12.

3 Biochemistry Department, Ankara Atatürk Education and Research Hospital, Ankara, Turkey.

Purpose: The aim of this study was to evaluate thiol/disulfide homeostasis and ischemia-modified albumin levels with primary open-angle glaucoma, ocular hypertension, and control group; also to interpret the correlation between these biochemical parameters and retinal nerve fiber layer analysis.

Material And Methods: In a prospective cross-sectional study, 30 primary open-angle glaucoma cases, 30 ocular hypertension cases, and 30 control subjects were included in the study. Native thiol, total thiol, and disulfide measurements and disulfide/native thiol, disulfide/total thiol, and native thiol/total thiol ratios were evaluated as thiol-disulfide homeostasis. Read More

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http://dx.doi.org/10.1177/1120672119839582DOI Listing

Genetic correlation between Prothrombin G20210A polymorphism and retinal vein occlusion risk.

Braz J Med Biol Res 2019 Apr 8;52(4):e8217. Epub 2019 Apr 8.

Department of Refraction and Cornea, Tianjin Medical University Eye Hospital, School of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, China.

The aim of this study was to perform an updated meta-analysis to quantitatively investigate the association between G20210A polymorphism of Prothrombin gene and the risk of retinal vein occlusion (RVO), based on the available publications with inconsistent results. We utilized the Stata software to perform the heterogeneity test, association test, Begg's and Egger's tests, and sensitivity analysis. We searched three on-line databases (PubMed, Embase, and WOS) and obtained a total of 422 articles. Read More

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http://dx.doi.org/10.1590/1414-431X20198217DOI Listing

[Susac Syndrome: A Diagnostic Chameleon].

Laryngorhinootologie 2019 Apr 9;98(4):268-275. Epub 2019 Apr 9.

Susac's syndrome (SuS) is a rare, probably autoimmune endotheliopathy of the central nervous system, retina and inner ear. It is characterized by a clinical triad of encephalopathy, branch retinal artery occlusions (BRAOs) and sensorineural hearing loss. To date, more than 300 cases of SuS have been reported in the literature. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0747-6916
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http://dx.doi.org/10.1055/a-0747-6916DOI Listing
April 2019
2 Reads

REVERSE SUTURE TECHNIQUE FOR INTRAOCULAR LENS REFIXATION.

Retin Cases Brief Rep 2019 Apr 5. Epub 2019 Apr 5.

North Carolina Retina Associates, Raleigh, North Carolina.

Purpose: To describe a novel reverse suture approach to safely and securely refixate dislocated intraocular lenses (IOLs).

Methods: We describe two cases herein where we use a reverse suture technique to refixate dislocated IOLs. By reversing the needle-holder grasp on a Gore-Tex suture needle, we can safely insert the base of the needle through the pars plana. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000867DOI Listing

Spectral Domain Optical Coherence Tomography in Detecting Sub-Clinical Retinal Findings in Asian Indian Children with Down Syndrome.

Curr Eye Res 2019 Apr 8:1-7. Epub 2019 Apr 8.

e Department of Ophthalmology , Narayana Nethralaya Eye Institute , Bangalore , India.

Purpose: Trisomy 21, also known as Down syndrome (DS), is the most common trisomy worldwide. Although ocular associations have been reported, retinal anatomy and pathology remain uninvestigated. We evaluate the role of spectral domain optical coherence tomography (SD-OCT) in analyzing foveal morphology of children with DS. Read More

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http://dx.doi.org/10.1080/02713683.2019.1597128DOI Listing

Retinal vein occlusion is associated with low blood high-density lipoprotein cholesterol: a nationwide cohort study.

Am J Ophthalmol 2019 Apr 5. Epub 2019 Apr 5.

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Purpose: To investigate association between the development of retinal vein occlusion (RVO) and blood high-density lipoprotein cholesterol (HDL-C).

Design: A retrospective, nationwide, population-based cohort study.

Methods Setting: Republic of Korea STUDY POPULATION: This study included 23,149,403 people aged 20 years or older who underwent the Korean National Health Screening Program examination between January 2009 and December 2012. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029394193015
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http://dx.doi.org/10.1016/j.ajo.2019.04.001DOI Listing
April 2019
8 Reads

An Internal Limiting Membrane Plug and Gas Endotamponade for Recurrent or Persistent Macular Hole.

J Ophthalmol 2019 7;2019:6051724. Epub 2019 Mar 7.

Dipartimento Neuro-muscoloscheletrico e Organi di Senso, Azienda Ospedaliera Universitaria di Careggi, Florence, Italy.

Introduction: Recurrent or persistent macular holes (MHs) are rare today due to the tendency to carefully peel the internal limiting membrane. Conversely, their treatment is still a challenge for a vitreoretinal surgeon.

Materials And Methods: This is a retrospective, consecutive, and nonrandomized study of patients affected by recurrent or persistent MHs treated using small-gauge pars plana vitrectomy (25- or 23-gauge) and an autologous ILM plug, at the Eye Clinic of Azienda Ospedaliera Universitaria Careggi (Florence, Italy) between January 2016 and May 2018. Read More

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http://dx.doi.org/10.1155/2019/6051724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431435PMC

Long-term Clinical Results of Vitrectomy and Scleral Buckling in Treatment of Rhegmatogenous Retinal Detachment.

ScientificWorldJournal 2019 6;2019:5416806. Epub 2019 Mar 6.

Department of Ophthalmology, RWTH Aachen University, Aachen, Germany.

Purpose: Most studies about retinal detachment cover a limited follow-up period. The purpose of this research is to assess the long-term results after pars plana vitrectomy (PPV) and scleral buckle (SB) surgery in patients with rhegmatogenous retinal detachment (RRD).

Methods: 155 patients with RRD are treated either with SB or PPV with a mean follow-up of more than 5 years. Read More

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https://www.hindawi.com/journals/tswj/2019/5416806/
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http://dx.doi.org/10.1155/2019/5416806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431356PMC
March 2019
3 Reads

Direct carotid puncture for endovascular thrombectomy in acute ischemic stroke.

J Neurointerv Surg 2019 Apr 6. Epub 2019 Apr 6.

Interventional Neuroradiology Service, Department of Radiology, Beaumont Hospital, Dublin, Ireland.

Background: Mechanical thrombectomy is the standard of care for acute ischemic strokes with proximal intracranial occlusion. Arterial access is commonly achieved with femoral artery puncture, although this is not always possible. In this case series, we describe 11 cases of anterior circulation stroke where direct carotid puncture was used to obtain vascular access. Read More

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http://dx.doi.org/10.1136/neurintsurg-2018-014586DOI Listing
April 2019
2 Reads

A human amniotic membrane plug to repair retinal detachment associated with large macular tear.

Acta Ophthalmol 2019 Apr 6. Epub 2019 Apr 6.

Department of Translational Surgery and Medicine, Ophthalmology, University of Florence, Careggi, Florence, Italy.

Purpose: To describe a surgical technique, using a human amniotic membrane (hAM) plug, in two cases of retinal detachment with a large macular tear.

Methods: Surgical technique description with surgical video. A 23-gauge pars plana vitrectomy with peripheral retinectomy was performed. Read More

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http://dx.doi.org/10.1111/aos.14109DOI Listing
April 2019
1 Read

Automated Framework for Screening of Glaucoma Through Cloud Computing.

J Med Syst 2019 Apr 6;43(5):136. Epub 2019 Apr 6.

Center for Advanced Studies, Dr. A.P.J. Abdul Kalam Technical University, Lucknow, Uttar Pradesh, India.

In recent times, the use of computer aided diagnosis for detection of Glaucoma from fundus images has been prevalent. In the proposed work, a cloud based system is proposed for automatic and real-time screening of Glaucoma with the use of automatic image processing techniques. The proposed system offers scalability to the developers and easy accessibility to the consumers. Read More

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http://dx.doi.org/10.1007/s10916-019-1260-2DOI Listing

Characteristics of Behcet's Disease in the American Southwest.

Semin Arthritis Rheum 2019 Mar 9. Epub 2019 Mar 9.

DOIM-Rheum, MSC 10 5550, University of New Mexico Health Sciences Center, 5th FL ACC, Albuquerque, NM 87131, United States.

Objective: The goal of this study was to determine the characteristics of Behçet's disease (BD) in the American Southwest.

Material And Methods: This was a cross-sectional study of BD patients clinically encountered during a 2-year period. All subjects fulfilled the International Study Group criteria (ISG) or International Criteria for Behcet's Disease (ICBD). Read More

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http://dx.doi.org/10.1016/j.semarthrit.2019.03.003DOI Listing
March 2019
2 Reads

Ocular Point-of-Care Ultrasound in the Pediatric Emergency Department.

Pediatr Emerg Care 2019 Feb 14. Epub 2019 Feb 14.

Department of Pediatric Emergency Medicine, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.

Objective: Point-of-care ultrasound has become an important adjunct for diagnostic assessment in pediatric emergency medicine. In this case series, we demonstrate how ocular point-of-care ultrasound is used to correctly diagnose ocular pathologies and to expedite care.

Methods/results: We present a series of cases in which the point-of-care ultrasound ocular examination proved valuable in the timely diagnosis of pathologies involving the lens, vitreous, retina, and retrobulbar segment of the eye. Read More

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http://dx.doi.org/10.1097/PEC.0000000000001762DOI Listing
February 2019

PHOTODYNAMIC THERAPY FOR EXTRAFOVEOLAR CHOROIDAL OSTEOMA.

Retina 2019 Apr 2. Epub 2019 Apr 2.

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.

Purpose: To evaluate the outcome of photodynamic therapy (PDT) in the management of extrafoveolar choroidal osteoma.

Methods: The authors performed a retrospective chart review of all patients with choroidal osteoma that did not involve the foveola and were treated with standard-fluence PDT.

Results: Nine eyes with extrafoveolar choroidal osteoma were studied. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002534DOI Listing

The identification of a RNA splice variant in TULP1 in two siblings with early-onset photoreceptor dystrophy.

Mol Genet Genomic Med 2019 Apr 4:e660. Epub 2019 Apr 4.

Department of Human Genetics, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands.

Background: Early-onset photoreceptor dystrophies are a major cause of irreversible visual impairment in children and young adults. This clinically heterogeneous group of disorders can be caused by mutations in many genes. Nevertheless, to date, 30%-40% of cases remain genetically unexplained. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/mgg3.660
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http://dx.doi.org/10.1002/mgg3.660DOI Listing
April 2019
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Longitudinal Retinal Perfusion Status in Eyes with Diabetic Macular Edema Receiving Intravitreal Aflibercept or Laser in VISTA study.

Ophthalmology 2019 Apr 1. Epub 2019 Apr 1.

Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States.

Purpose: To evaluate changes in retinal perfusion status with intravitreal aflibercept injection (IAI) and laser treatment in the phase 3 VISTA study of patients with diabetic macular edema (DME).

Design: Post-hoc analysis of a double-masked, randomized, active-controlled, phase 3 trial.

Participants: Patients with center-involved DME in the study eye. Read More

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http://dx.doi.org/10.1016/j.ophtha.2019.03.040DOI Listing

Unilateral cilioretinal artery occlusion following cannabis use.

Ther Adv Ophthalmol 2019 Jan-Dec;11:2515841419838661. Epub 2019 Mar 27.

Moorfields Eye Hospital, London, UK.

There is a growing trend towards the decriminalization of cannabis and this is associated with its increased use over the past decade. Although a variety of adverse effects are attributed to its use, complications involving the eye are rare. We present the case of cilioretinal artery occlusion in a young man with no previous medical history. Read More

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http://dx.doi.org/10.1177/2515841419838661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437321PMC
March 2019
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The Natural History of Congenital X-Linked Retinoschisis and Conversion between Phenotypes over Time.

Ophthalmol Retina 2019 Jan 24;3(1):77-82. Epub 2018 Aug 24.

Associated Retinal Consultants, William Beaumont Hospital, Royal Oak, Michigan; William Beaumont School of Medicine, Oakland University, Rochester, Michigan. Electronic address:

Purpose: To evaluate the natural history of congenital X-linked retinoschisis (CXLRS) and to assess disease stability or progression over time.

Design: Retrospective case series at a single-center, tertiary care, pediatric retina practice.

Participants: One hundred two eyes of 51 patients with CXLRS. Read More

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http://dx.doi.org/10.1016/j.oret.2018.08.006DOI Listing
January 2019

Anatomic Response to Intravitreal Dexamethasone Implant and Baseline Aqueous Humor Cytokine Levels in Diabetic Macular Edema.

Invest Ophthalmol Vis Sci 2019 Apr;60(5):1336-1343

Institut Clínic d'Oftalmologia (ICOF), Hospital Clínic, Barcelona, Spain.

Purpose: To determine whether baseline cytokine aqueous humor (AH) levels are associated with diabetic macular edema (DME) anatomic response to dexamethasone intravitreal implant (DEX) injection.

Methods: This was a prospective cohort study of DME cases receiving DEX treatment. Seventy patients were recruited with center-involving DME with spectral-domain (SD) optical coherence tomography (OCT) detection of central macular thickness (CMT) ≥300 μm on macular cube 518 × 128-μm scan protocol (Cirrus SD-OCT). Read More

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http://dx.doi.org/10.1167/iovs.18-26215DOI Listing

MULTILAYERED OPTIC DISK HEMORRHAGE IN ADULTS WITHOUT A POSTERIOR VITREOUS DETACHMENT.

Retin Cases Brief Rep 2019 Mar 28. Epub 2019 Mar 28.

Retina Service, New England Eye Center, Tufts Medical Center, Boston, Massachusetts.

Purpose: To describe 2 cases of multilevel optic disk hemorrhages in adults without a posterior vitreous detachment.

Methods: The findings on clinical examination, color fundus photography, fluorescein angiography, spectral domain optical coherence tomography at presentation and follow-up are presented.

Results: Two patients ages 61 and 49 years presented with unilateral floaters secondary to microscopic vitreous hemorrhage. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000864DOI Listing

A NOVEL SURGICAL TECHNIQUE FOR RESCUING A DISLOCATED ACCOMMODATIVE INTRAOCULAR LENS (CRYSTALENS).

Retin Cases Brief Rep 2019 Mar 28. Epub 2019 Mar 28.

New Jersey Retina, New Brunswick, New Jersey.

Purpose: To describe a novel surgical technique for rescuing a dislocated "in-the-bag" accommodative intraocular lens (Crystalens; Bausch and Lomb Inc, Rochester NY) and report its postoperative outcome.

Methods: Interventional case report. An 82-year-old patient with history of pseudoexfoliation syndrome presented with a posteriorly dislocated "in-the-bag" Crystalens intraocular lens. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000865DOI Listing

INVOLUTION OF NEOVASCULAR AGE-RELATED MACULAR DEGENERATION AFTER ENDOPHTHALMITIS.

Retin Cases Brief Rep 2019 Mar 28. Epub 2019 Mar 28.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.

Purpose: To report patients who demonstrated an alteration in the clinical and optical coherence tomography features of neovascular age-related macular degeneration after resolution of endophthalmitis.

Methods: Retrospective case series of the subsequent changes in the macula and need for anti-vascular endothelial growth factor therapy in patients with neovascular age-related macular degeneration who developed endophthalmitis after intravitreal injection.

Results: The study included seven eyes of seven patients with follow-up ranging between 3 months and 11 years. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000866DOI Listing

SEGMENTAL DIFFUSE VASCULAR LEAKAGE: A FLUORESCEIN ANGIOGRAPHIC FINDING IN PATIENTS WITH VON HIPPEL-LINDAU DISEASE.

Retin Cases Brief Rep 2019 Mar 28. Epub 2019 Mar 28.

Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Purpose: To describe a novel fluorescein angiographic finding in patients with von Hippel-Lindau disease.

Methods: Retrospective case series of patients diagnosed with retinal capillary hemangioblastoma (RCH) in the setting of von Hippel-Lindau.

Results: We identified six eyes of three patients with von Hippel-Lindau and leaky retinal vessels. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000868DOI Listing
March 2019
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SPONTANEOUS CLOSURE OF A MACULAR HOLE RESULTING FROM YAG LASER CAPSULOTOMY IN A 13-YEAR-OLD GIRL.

Retin Cases Brief Rep 2019 Mar 28. Epub 2019 Mar 28.

Dell Medical School, University of Texas Austin, Austin, Texas.

Purpose: To describe the novel finding of spontaneous resolution of a full-thickness macular hole resulting from YAG laser capsulotomy in a 13-year-old girl with previous history of retinal detachment repair and cataract surgery.

Methods: A 13-year-old girl who had developed a macular hole after YAG laser was noted to have spontaneous resolution of the macular hole at 2-week follow-up visit with concurrent increase in visual acuity. Institutional review board was not applicable for this case. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000871DOI Listing
March 2019
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