Search our Database of Scientific Publications and Authors

I’m looking for a

    18 results match your criteria Reticulate Pigmented Anomaly

    1 OF 1

    Dowling-Degos disease: classic clinical and histopathological presentation.
    An Bras Dermatol 2011 Sep-Oct;86(5):979-82
    Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro, Brasil.
    Dowling-Degos disease (DDD) is a rare genetic disease of the skin (reticulate pigmented anomaly), clinically characterized by flexural brown pigmented reticulate macules, comedo-like papules on the back, neck and pitted perioral or facial scars. We present the case of a 51 year-old man with macrocomedo-like lesions, pitted scars, cysts, hyperpigmented macules in his back, chest, axillae, neck, groin and face. The patient reported having two children, three brothers and a father with a similar condition. Read More

    A gene locus responsible for reticulate pigmented anomaly of the flexures maps to chromosome 17p13.3.
    J Invest Dermatol 2006 Jun;126(6):1297-301
    Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
    Reticulate pigmented anomaly of the flexures (RPAF), also called Dowling-Degos disease, is a rare autosomal-dominant cutaneous disorder characterized by spotted and reticulate pigmentation of the flexures. The gene, or even the chromosomal location, for RPAF has not yet been identified. In this study, one Chinese family with RPAF was identified and subjected to a genomewide screen for linkage analysis. Read More

    Dowling-Degos disease (reticulate pigmented anomaly of the flexures): a clinical and histopathologic study of 6 cases.
    J Am Acad Dermatol 1999 Mar;40(3):462-7
    Department of Dermatology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.
    Background: Few case series describing Dowling-Degos disease (DDD) have been reported.

    Objective: Our purpose was to review the clinical and histopathologic findings in DDD.

    Methods: We reviewed the clinical and histopathologic findings in 6 patients with DDD who were evaluated at the Mayo Clinic. Read More

    Genodermatosis with reticulate, patchy and mottled pigmentation of the neck--a clue to rare dermatologic disorders.
    Dermatology 1998 ;197(3):281-90
    Department of Dermatology, University of Basel, and Abteilung für Dermatologie, Kantonsspital Aarau, Switzerland.
    Reticulate pigmentation of the neck is a common finding in numerous genodermatoses and acquired diseases. As the neck is readily accessible to medical inspection, it may serve as a diagnostic window for various dermatoses. Several entities out of the spectrum of ectodermal dysplasia present with reticulate or mottled pigmentation on the upper trunk and neck. Read More

    Dowling-Degos disease, hidradenitis suppurativa, and multiple keratoacanthomas. A disorder that may be caused by a single underlying defect in pilosebaceous epithelial proliferation.
    J Am Acad Dermatol 1991 May;24(5 Pt 2):888-92
    Division of Dermatology, USF College of Medicine, Tampa 33612.
    We report a case in which one patient had Dowling-Degos disease (reticulate pigmented anomaly of the flexures), hidradenitis suppurativa, and multiple keratoacanthomas. Abnormal epithelial proliferation involving mainly the pilosebaceous apparatus has been recognized in all three conditions. We speculate that a single underlying defect in follicular epithelial proliferation, characterized by variable expressivity, accounts for the coexistence of these clinically distinct disorders of follicular derivation. Read More

    Reticulate nonmelanocytic hyperpigmentation anomaly. A probable variant of Dowling-Degos disease.
    Int J Dermatol 1991 Jan;30(1):39-42
    Department of Medicine, Cleveland Clinic Foundation, Ohio.
    A 26-year-old white woman had reticulate nonmelanocytic hyperpigmentation anomaly characterized by partially blanching red-brown papules and macules and a histologic picture of digitate epithelial budding proliferation with lightly pigmented rete ridges. Except for the classically described hyperpigmentation at the rete ridge tips, the patient has Dowling-Degos disease. This case of a reticulate nonmelanocytic hyperpigmentation anomaly is probably a variant of Dowling-Degos disease. Read More

    Reticulate pigmented anomaly of the flexures (Dowling-Degos disease): a case report associated with hidradenitis suppurativa and squamous cell carcinoma.
    Cutis 1990 Jun;45(6):446-50
    Department of Dermatology, Cleveland Clinic Foundation, Ohio.
    We report the first case of reticulate pigmented anomaly of the flexures (Dowling-Degos disease) associated with hidradenitis suppurativa. Our patient also showed a squamous cell carcinoma of the groin, which is a rare complication of hidradenitis suppurativa. The relationship between Dowling-Degos disease and hidradenitis is discussed and the literature on squamous cell carcinoma and hidradenitis suppurativa is reviewed. Read More

    [Dowling-Degos disease: unsuccessful therapeutic trial with retinoids].
    Hautarzt 1987 Oct;38(10):615-8
    Dermatologische Abteilung, Krankenhauses der Stadt Wien-Lainz.
    A patient with the typical features of Dowling-Degos disease (reticulate pigmented anomaly of the flexures) is described; the clinical picture and differential diagnosis are discussed. Systemic retinoids were used for treatment, but no essential improvement could be observed. Read More

    Reticulate pigmented anomaly of the flexures associating reticulate acropigmentation: one single entity.
    J Am Acad Dermatol 1986 Feb;14(2 Pt 2):359-61
    We describe a patient and her family in whom the clinical features of reticulate pigmented anomaly of the flexures, also known as Dowling-Degos disease, are associated with those of Kitamura's reticulate acropigmentation. This family is the second in which the concurrence of such rare genodermatoses is reported. It seems likely that Dowling-Degos disease, and Kitamura's reticulate acropigmentation are different clinical expressions of the same entity. Read More

    [Reticulated pigment anomaly of the skinfolds].
    Med Cutan Ibero Lat Am 1983 ;11(2):83-8
    We report a case of reticulate pigmented anomaly of the flexures in a 54 years-old white male patient. His lesions had developed during the last 30 years, involving neck, axillae, groins, anterior chest wall, scrotum, buttocks and thighs. The abnormality is characterized by pigmented epidermal downgrowths, with similar lesions developing around dilated pilosebaceous follicles. Read More

    Reticulate pigmented anomaly of the flexures. Case reports and genetic investigation.
    Arch Dermatol 1982 Jul;118(7):490-3
    Reticulate pigmented anomaly of the flexures is a pigmented macular disease characterized by punctate, hyperpigmented macules on the flexural areas. Histopathologic findings include acanthosis, keratinization of the follicular infundibulum, and filiform downgrowths of epidermal cells. Examination of a family has revealed the presence of the disease in six members. Read More

    Reticulate pigmented anomaly.
    Cutis 1980 Oct;26(4):380-1
    Reticulate pigmented anomaly of the flexures is a benign, recently described genodermatosis reported to involve the flexural areas as well as the scrotum. Described herein is a twenty-nine year old man in whom the characteristic speckled macules were limited to the scrotal and penile skin. The authors suggest that the anomaly be designated reticulate pigmented anomaly without reference to specific anatomic sites. Read More

    Reticulate pigmented anomaly of the flexures. Dowing Degos disease, a new genodermatosis.
    Arch Dermatol 1978 Aug;114(8):1150-7
    Acquired reticulate pigmentation of the flexures developed in ten patients. Additional features in some cases were pitted scars near the angles of the mouth and scattered dark comedone-like lesions on the neck (dark dot follicles). The disease affects both sexes, usually develops in early adult life, and is slowly progressive. Read More

    1 OF 1