7,375 results match your criteria Resuscitation[Journal]


Stenosis and revascularization of the coronary artery are associated with outcomes in presumed cardiogenic arrest survivors: a multi-center retrospective cohort study.

Resuscitation 2019 Feb 14. Epub 2019 Feb 14.

Department of Emergency Medicine, National Taiwan University Medical College and Hospital, Taipei, Taiwan. Electronic address:

Background: The emergent coronary angiography (CAG) is associated with better outcomes in CA survivors. However, the impact of severity and revascularization of coronary artery stenosis on outcomes in cardiac arrest (CA) survivors remains unclear.

Methods: A total of 273 non-traumatic adult CA survivors who underwent emergent CAG from January 2011 to July 2017 were retrospectively recruited. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.040DOI Listing
February 2019

Guideline removal of atropine and survival after adult in-hospital cardiac arrest with a non-shockable rhythm.

Resuscitation 2019 Feb 13. Epub 2019 Feb 13.

Research Center for Emergency Medicine, Department of Clinical Medicine, Aarhus Universitsy Hospital, Aarhus, Denmark; Center for Resuscitation Science, Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Aim: To determine whether the removal of atropine from the 2010 ACLS guidelines for non-shockable cardiac arrests was associated with a change in survival.

Methods: Using the Get With The Guidelines®-Resuscitation registry, we included adults with an index in-hospital cardiac arrest between 2006 and 2015. The primary outcome was survival to hospital discharge. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.02.002DOI Listing
February 2019

Clinical characteristics and outcomes of witnessed hypothermic cardiac arrest: a systematic review on rescue collapse.

Resuscitation 2019 Feb 13. Epub 2019 Feb 13.

Emergency Department, Lausanne University Hospital, Lausanne, Switzerland. Electronic address:

Aims: Cardiac arrest related to accidental hypothermia may occur at temperatures below 32 °C. Our goal was to describe the clinical characteristics and outcomes of patients who suffered from witnessed hypothermic cardiac arrest (CA) and assess the occurrence of hypothermic CA as a function of patient body temperature.

Methods: We conducted a systematic review of the literature on cases of hypothermic CA due to rescue collapse. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.02.001DOI Listing
February 2019

Variability in survival and post-cardiac arrest care following successful resuscitation from out-of-hospital cardiac arrest.

Resuscitation 2019 Feb 13. Epub 2019 Feb 13.

Center for Resuscitation Science and Department of Emergency Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

Aim Of The Study: Regionalization of care for out-of-hospital cardiac arrests (OHCA) may improve patient outcomes. We evaluated inter-hospital variations in post-arrest care provision and the relation between hospital case volume and survival in Pennsylvania.

Methods: This retrospective study (2013-2017) used data from adult OHCA cases in Pennsylvania from the Cardiac Arrest Registry to Enhance Survival. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.02.004DOI Listing
February 2019

Effect of cancer history on post-resuscitation treatments in out-of-hospital cardiac arrest.

Resuscitation 2019 Feb 13. Epub 2019 Feb 13.

Department of Emergency Medicine, Seoul National University Hospital, Laboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Research Institute, Seoul, Republic of Korea. Electronic address:

Objectives: There is growing evidence that optimal post-resuscitation treatment is a significant factor for overall survival and neurological outcomes in out-of-hospital cardiac arrest (OHCA). However, there is also growing evidence of disparities in treatments in vulnerable populations such as elderly individuals or patients with underlying diseases, including cancer.

Aim: The aim of this study was to evaluate the influence of cancer status on post-resuscitation therapies among OHCA patients. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.02.005DOI Listing
February 2019

The role of extracorporeal life support in patients with hypothermic cardiac arrest.

Resuscitation 2019 Jan;134:157-158

Department of Anaesthesiology and Intensive Care, Medical University of Silesia, Medyków 16, Katowice, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.resuscitation.2018.10.015DOI Listing
January 2019

Impact of Right Ventricular Dysfunction on Mortality in Adults with Cardiac Arrest Undergoing Coronary Angiogram.

Resuscitation 2019 Feb 12. Epub 2019 Feb 12.

Division of Cardiovascular Medicine, Department of Medicine, State University of New York at Stony Brook, Stony Brook, NY, USA.

Objective: We sought to identify the impact of echocardiographic right ventricular (RV) systolic dysfunction on mortality in adults with cardiac arrest (CA).

Methods: The study population included 147 adults hospitalized with CA who underwent both echocardiogram and coronary angiogram at an academic tertiary medical center. The primary outcome of interest was all-cause in-hospital mortality. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.02.003DOI Listing
February 2019

Racial and ethnic differences in outcomes after out-of-hospital cardiac arrest: Hispanics and Blacks may fare worse than non-Hispanic Whites.

Resuscitation 2019 Feb 10;137:29-34. Epub 2019 Feb 10.

Harbor-UCLA Medical Center and the Los Angeles Biomedical Research Institute at Harbor-UCLA, 1000 W Carson Street, Torrance, CA, United States; The David Geffen School of Medicine at UCLA, 405 Hilgard Ave, Los Angeles, CA, United States.

Background: This study evaluates differences in out-of-hospital cardiac arrest (OHCA) characteristics, interventions, and outcomes by race/ethnicity.

Methods: This is a retrospective analysis from a regionalized cardiac system. Outcomes for all adult patients treated for OHCA with return of spontaneous circulation (ROSC) were identified from 2011-2014. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.038DOI Listing
February 2019

Does endotracheal intubation increases chest compression fraction in out of hospital cardiac arrest: a substudy of the CAAM trial.

Resuscitation 2019 Feb 9. Epub 2019 Feb 9.

Urgences Adultes, CHU Saint Pierre, Rue Haute, Bruxelles, 1000, Belgium.

Background: Optimal out of hospital cardiac arrest (OHCA) airway management strategies remain unclear. We compared chest compression fraction (CCF) between patients receiving endotracheal intubation (ETI) versus bag mask ventilation (BMV).

Methods: We studied adult OHCA enrolled from our center in the CAAM trial. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.032DOI Listing
February 2019
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Multimodal assessment using early brain CT and blood pH improve prediction of neurologic outcomes after pediatric cardiac arrest.

Resuscitation 2019 Feb 5;137:7-13. Epub 2019 Feb 5.

Department of Pediatrics, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea. Electronic address:

Background: Early prediction of neurologic prognosis in children resuscitated from cardiac arrest is a major challenge. This study aimed to investigate the usefulness of a combined model based on brain computed tomography (CT) and initial blood gas analysis to predict neurologic prognoses in pediatric patients after cardiac arrest.

Methods: We retrospectively analyzed the medical records of patients resuscitated after cardiac arrest from 2000 to 2018. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.033DOI Listing
February 2019

The prevalence of psychiatric disorders in sudden cardiac arrest survivors: A 5-year nationwide inpatient analysis.

Resuscitation 2019 Feb 5;136:131-135. Epub 2019 Feb 5.

Division of Cardiology, Atlanta VA Medical Center, Decatur, GA, USA; Division of Cardiology, Emory University School of Medicine, Atlanta, GA, USA; Division of Cardiology, Morehouse School of Medicine, Atlanta, GA, USA.

Background: Sudden cardiac arrest (SCA) is a major public health challenge in the United States (US). At present, the existence of limited literature on psychological sequelae post-cardiac arrest is a challenge in providing optimal care to survivors.

Aim: The aim of this study is to determine the prevalence of various psychiatric comorbidities in survivors of SCA. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.035DOI Listing
February 2019
1 Read

Sex differences in the quality-of-life and functional outcome of cardiac arrest survivors.

Resuscitation 2019 Feb 5;137:21-28. Epub 2019 Feb 5.

Centre for Research and Evaluation, Ambulance Victoria, Doncaster, Victoria, Australia; Department of Epidemiology and Preventive Medicine, Monash University, Prahran, Victoria, Australia; Department of Community Emergency Health and Paramedic Practice, Monash University, Frankston, Victoria, Australia; Discipline of Emergency Medicine, University of Western Australia, Crawley, Western Australia, Australia.

Aim: Although survival from out-of-hospital cardiac arrest (OHCA) is improving, little is known about the long-term outcome of survivors. In this study, we assess the impact of sex on 12 month functional recovery and health-related quality-of-life (HRQoL) outcomes in OHCA survivors.

Methods: Between 2010 and 2016, consecutive adult OHCA survivors were invited to participate in structured telephone interviews using the Glasgow Outcome Scale-Extended (GOSE), the EuroQol-5D (EQ-5D), and 12-Item Short Form (SF-12) health survey. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.034DOI Listing
February 2019

Extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest: Ethical considerations.

Resuscitation 2019 Feb 4;137:1-6. Epub 2019 Feb 4.

Sunnybrook Center for Prehospital Medicine, Canada; Department of Family Community Medicine, Division of Emergency Medicine, University of Toronto, Canada.

Out-of-hospital cardiac arrest (OHCA) continues to be a leading cause of mortality worldwide. In Canada over 40,000 cardiac arrests that occur each year, a majority occur unexpectedly outside of the hospital setting. However, the reality is that without rapid and appropriate treatment within minutes, most victims will die before reaching the hospital. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.036DOI Listing
February 2019
3 Reads

Training of potential trainers on lay-people CPR in Vietnam.

Resuscitation 2019 Feb 1. Epub 2019 Feb 1.

Hanoi Medical University Hospital and Hanoi Medical University, 01 Ton That Tung Street, Hanoi, Vietnam.

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.030DOI Listing
February 2019

Do we need continuous electroencephalography after cardiac arrest?

Resuscitation 2019 Feb 1. Epub 2019 Feb 1.

Maine Medical Center Department of Critical Care Services and Neuroscience Institute, Portland, Maine, USA. Electronic address:

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.026DOI Listing
February 2019

Cost-utility of extracorporeal cardiopulmonary resuscitation in patients with cardiac arrest.

Resuscitation 2019 Feb 1;136:126-130. Epub 2019 Feb 1.

Department of Medicine, University of Chicago Medical Center, 5841 South Maryland Avenue, Chicago, IL, 60637, United States.

Background: Extracorporeal cardiopulmonary resuscitation (ECPR) is a resource-intensive tool that provides haemodynamic and respiratory support in patients who have suffered cardiac arrest. In this study, we investigated the cost-utility of ECPR (cost/QALY) in cardiac arrest patients treated at our institution.

Methods: We performed a retrospective review of patients who received ECPR following cardiac arrest between 2012 and 2018. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.027DOI Listing
February 2019
3 Reads

Platelet dysfunction after Out of Hospital Cardiac Arrest. Results from POHCAR: A prospective observational, cohort study.

Resuscitation 2019 Feb 1;136:105-111. Epub 2019 Feb 1.

Academic Department of Emergency Care, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.

Aim: Coagulation and platelet function following out of hospital cardiac arrest (OHCA) at admission to a UK cardiology centre were investigated prospectively in this observational feasibility study, and compared to that of patients receiving percutaneous coronary intervention (PCI) for ST segment elevation myocardial infarction (STEMI).

Method: Blood samples taken immediately at emergency department admission from patients after OHCA of probable cardiac origin were analysed using near-patient thromboelastometry and a platelet function analyser. Physiological parameters, demographic information, bleeding rates and 30-day survival were recorded, and compared to that of patients undergoing PCI for STEMI. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.025DOI Listing
February 2019
1 Read

Reasons for death in patients successfully resuscitated from out-of-hospital and in-hospital cardiac arrest.

Resuscitation 2019 Jan 30;136:93-99. Epub 2019 Jan 30.

Center for Resuscitation Science, Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA. Electronic address:

Introduction: There is no standard for categorizing reasons for death in those who achieve return of spontaneous circulation (ROSC) after cardiac arrest but die before hospital discharge. Categorization is important for comparing outcomes across studies, assessing benefits of interventions, and developing quality-improvement initiatives. We developed and tested a method for categorizing reasons for death after cardiac arrest in both in-hospital (IHCA) and out-of-hospital (OHCA) arrests. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.031DOI Listing
January 2019
2 Reads

Repeated adrenaline doses and survival from an out-of-hospital cardiac arrest.

Resuscitation 2019 Jan 29. Epub 2019 Jan 29.

Warwick Clinical Trials Unit, University of Warwick, Coventry, CV4 7AL, United Kingdom; University Hospitals Birmingham NHS Foundation Trust, Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, United Kingdom.

Background: Adrenaline is the primary drug of choice for resuscitation from out-of-hospital cardiac arrest (OHCA). Although adrenaline may increase the chance of achieving return of spontaneous circulation (ROSC), there is limited evidence that repeated doses of adrenaline improves overall survival, and increasing evidence of a detrimental effect on neurological function in survivors. This paper reports the relationship between repeated doses of adrenaline and survival in a cohort of patients attended by the London Ambulance Service in the United Kingdom. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.022DOI Listing
January 2019

The effect of intravenous adrenaline on electrocardiographic changes during resuscitation in patients with initial pulseless electrical activity in out of hospital cardiac arrest.

Resuscitation 2019 Jan 29;136:119-125. Epub 2019 Jan 29.

Department of Circulation and Medical Imaging, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway; St Olavs Hospital, Trondheim University Hospital, Department of Emergency Medicine and Pre-Hospital Services, Trondheim, Norway.

Introduction: Presence of electrocardiographic rhythm in the absence of palpable pulses defines pulseless electrical activity (PEA) and the electrocardiogram (ECG) may provide a source of information during resuscitation. The aim of this study was to examine the development of ECG characteristics during advanced life support (ALS) from Out-of-hospital cardiac arrest (OHCA) with initial PEA, and to explore the potential effects of adrenaline on these characteristics.

Methods: Patients with OHCA and initial PEA, part of randomized controlled trial of ALS with or without intravenous access and medications, were included. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.021DOI Listing
January 2019
1 Read

Survival to hospital discharge with biphasic fixed 360 joules versus 200 escalating to 360 joules defibrillation strategies in out-of-hospital cardiac arrest of presumed cardiac etiology.

Resuscitation 2019 Jan 29;136:112-118. Epub 2019 Jan 29.

Norwegian National Advisory Unit on Prehospital Emergency Medicine, Oslo University Hospital, Oslo, Norway. Electronic address:

Introduction: Guidelines recommend constant or escalating energy levels for shocks after the initial defibrillation attempt. Studies comparing survival to hospital discharge with escalating vs fixed high energy level shocks are lacking. We compared survival to hospital discharge for 200 J escalating to 360 J vs fixed 360 J in patients with initial ventricular fibrillation/pulseless ventricular tachycardia in a post-hoc analysis of the Circulation Improving Resuscitation Care trial database. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.020DOI Listing
January 2019
1 Read

Differences in durations, adverse events, and outcomes of in-hospital cardiopulmonary resuscitation between day-time and night-time: An observational cohort study.

Resuscitation 2019 Jan 29;137:14-20. Epub 2019 Jan 29.

Trauma and Acute Critical Care Medical Center, Tokyo Medical and Dental University Hospital of Medicine, 1-5-45, Yushima, Bunkyo-ku, Tokyo, Japan.

Background: Although patients with out-of-hospital cardiac arrest (OHCA) have a lower survival rate during night-time than during day-time, the cause of this difference remains unclear. We aimed to assess CPR parameters according to time period based on in-hospital cardiopulmonary resuscitation (IHCPR) duration and the frequency of iatrogenic chest injuries among OHCA patients.

Methods: This two-centre observational cohort study evaluated non-traumatic OHCA patients who were transferred between 2013-2016. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.023DOI Listing
January 2019
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Time to achieve desired fraction of inspired oxygen using a T-piece ventilator during resuscitation of preterm infants at birth.

Resuscitation 2019 Jan 29;136:100-104. Epub 2019 Jan 29.

Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands.

Aim: To determine the time between adjustment of FiO at the oxygen blender and the desired FiO reaching the preterm infant during respiratory support at birth.

Methods: This observational study was performed using a Neopuff T-piece Resuscitator attached to either a test lung (during initial bench tests) or a face mask during the stabilization of infants at birth. FiO was titrated following resuscitation guidelines. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03009572183087
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http://dx.doi.org/10.1016/j.resuscitation.2019.01.024DOI Listing
January 2019
3 Reads

Resuscitation highlights in 2018.

Resuscitation 2019 Jan 26;135:168-175. Epub 2019 Jan 26.

Southmead Hospital, North Bristol NHS Trust, Bristol, BS10 5NB UK. Electronic address:

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.019DOI Listing
January 2019

Epinephrine for out of hospital cardiac arrest: A systematic review and meta-analysis of randomized controlled trials.

Resuscitation 2019 Jan 24;136:54-60. Epub 2019 Jan 24.

Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Naples, Italy; Department of Anesthesia and Intensive Care, Istituto di Ricovero e Cura a Carattere Scientifico Istituto Neurologico Mediterraneo, Neuromed, Pozzilli, Italy.

Objective: To evaluate the effectiveness of epinephrine, compared with control treatments, on survival at admission, ROSC, survival at discharge, and a favorable neurologic outcome in adult patients during OHCA.

Data Source: MEDLINE and PubMed from inception to August 2018.

Study Selection: Randomized controlled trials (RCTs) on adult patients after OHCA treated with epinephrine versus controls. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.016DOI Listing
January 2019

Wireless and continuous monitoring of vital signs in patients at the general ward.

Resuscitation 2019 Jan 24;136:47-53. Epub 2019 Jan 24.

Radboud REshape Innovation Center, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.

Background Clinical deterioration regularly occurs in hospitalized patients potentially resulting in life threatening events. Early warning scores (EWS), like the Modified Early Warning Score (MEWS), assist care givers in assessing patients' clinical situation, but cannot alert for deterioration between measurements. New devices, like the ViSi Mobile (VM) and HealthPatch (HP) allow for continuous monitoring and can alert deterioration in an earlier phase. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.017DOI Listing
January 2019
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Automated external defibrillator accessibility is crucial for bystander defibrillation and survival: A registry-based study.

Resuscitation 2019 Jan 22;136:30-37. Epub 2019 Jan 22.

Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark; Emergency Medical Services Copenhagen, University of Copenhagen, Denmark.

Aims Optimization of automated external defibrillator (AED) placement and accessibility are warranted. We examined the associations between AED accessibility, at the time of an out-of-hospital cardiac arrest (OHCA), bystander defibrillation, and 30-day survival, as well as AED coverage according to AED locations. Methods In this registry-based study we identified all OHCAs registered by mobile emergency care units in Copenhagen, Denmark (2008-2016). Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.014DOI Listing
January 2019
5 Reads

Association between county-level cardiopulmonary resuscitation training and changes in Survival Outcomes after out-of-hospital cardiac arrest over 5 years: A multilevel analysis.

Resuscitation 2019 Jan 21. Epub 2019 Jan 21.

Department of Epidemiology, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea. Electronic address:

Introduction: Associations between neighbourhood environments and survival outcomes after out-of-hospital cardiac arrests (OHCAs) have been proposed. The purpose of this study was to examine the association between county-level cardiopulmonary resuscitation (CPR) training rates and improvements in survival outcomes after OHCA over 5 years.

Methods: Emergency medical service (EMS)-treated OHCAs with cardiac etiology between 2012 and 2016 were analyzed, excluding cases witnessed by EMS providers. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.012DOI Listing
January 2019
2 Reads

Hospitals' extracorporeal cardiopulmonary resuscitation capabilities and outcomes in out-of-hospital cardiac arrest: A population-based study.

Resuscitation 2019 Jan 19;136:85-92. Epub 2019 Jan 19.

Department of Healthcare Epidemiology, Graduate School of Medicine and Public Health, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto-city, Kyoto, 606-8501, Japan. Electronic address:

Aim: Extracorporeal cardiopulmonary resuscitation (ECPR) is the emerging resuscitative strategy to save refractory ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT) patients. We investigated whether the receiving hospitals' ECPR capabilities are associated with outcomes in out-of-hospital cardiac arrest (OHCA) patients who have refractory VF or pulseless VT.

Methods: In a population-based cohort study performed in Kobe City, Japan, between 2010 and 2017, we identified all OHCA patients who had refractory VF or pulseless VT. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.013DOI Listing
January 2019
1 Read
4.167 Impact Factor

Machine learning as a supportive tool to recognize cardiac arrest in emergency calls.

Resuscitation 2019 Jan 18. Epub 2019 Jan 18.

Emergency Medical Services Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Denmark.

Background: Emergency medical dispatchers fail to identify approximately 25% of cases of out of hospital cardiac arrest, thus lose the opportunity to provide the caller instructions in cardiopulmonary resuscitation. We examined whether a machine learning framework could recognize out-of-hospital cardiac arrest from audio files of calls to the emergency medical dispatch center.

Methods: For all incidents responded to by Emergency Medical Dispatch Center Copenhagen in 2014, the associated call was retrieved. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.015DOI Listing
January 2019
3 Reads

Neuron-specific-enolase as a predictor of the neurologic outcome after cardiopulmonary resuscitation in patients on ECMO.

Resuscitation 2019 Jan 14;136:14-20. Epub 2019 Jan 14.

Department of General and Interventional Cardiology, University Heart Center Hamburg Eppendorf, Hamburg, Germany. Electronic address:

Background: Neuron-specific-enolase (NSE) is frequently used to predict the neurologic outcome in persistently unconscious patients after cardiopulmonary resuscitation (CPR). However, its predictive value is unclear in the setting of veno-arterial extracorporeal membrane oxygenation therapy (ECMO). Aim of this project is to evaluate the predictive value of NSE in ECMO patients. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.011DOI Listing
January 2019

The acute respiratory distress syndrome after out-of-hospital cardiac arrest: Incidence, risk factors, and outcomes.

Resuscitation 2019 Jan 14;135:37-44. Epub 2019 Jan 14.

Division of Pulmonary, Critical Care, and Sleep Medicine, Harborview Medical Center, University of Washington, Seattle, WA, United States.

Objective: To define the incidence of the acute respiratory distress syndrome (ARDS) following out-of-hospital cardiac arrest (OHCA) and characterize its impact on outcome.

Methods: This was a retrospective cohort study conducted at two urban, tertiary, academic hospitals from 2007 to 2014. We included adults with non-traumatic OHCA and survived for ≥48 h. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03009572193000
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http://dx.doi.org/10.1016/j.resuscitation.2019.01.009DOI Listing
January 2019
4 Reads

Temporal trends in sudden cardiac death in Ontario, Canada.

Resuscitation 2019 Jan 14;136:1-7. Epub 2019 Jan 14.

Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada; Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada. Electronic address:

Aims: Although the prevention and treatment of cardiovascular conditions have significantly improved over the past decade, whether they have reduced the incidence of sudden cardiac death (SCD) is not known. We sought to evaluate the temporal trends of SCD in a large unselected population.

Methods: We conducted a population-based cohort study using multiple linked longitudinal data in Ontario Canada. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03009572183087
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http://dx.doi.org/10.1016/j.resuscitation.2019.01.010DOI Listing
January 2019
5 Reads

Effectiveness and safety of early enteral nutrition for patients who received targeted temperature management after out-of-hospital cardiac arrest.

Resuscitation 2019 Jan 14;135:191-196. Epub 2019 Jan 14.

Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Yoshidakonoecho, Sakyo-ku, Kyoto-city, Japan; Center for the Promotion of Interdisciplinary Education and Research, Kyoto University, Kyoto, Japan. Electronic address:

Aim: Early enteral nutrition (EN) is recommended for critically ill patients; however, few reports have examined early EN for patients who received targeted temperature management (TTM) after out-of-hospital cardiac arrest (OHCA). We investigated the effectiveness and safety of early EN for patients who received TTM after OHCA.

Methods: We used a nationwide Japanese administrative database to identify OHCA patients who received TTM from April 2008 to March 2017. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.007DOI Listing
January 2019
1 Read

Rhythm characteristics and patterns of change during cardiopulmonary resuscitation for in-hospital paediatric cardiac arrest.

Resuscitation 2019 Jan 9;135:45-50. Epub 2019 Jan 9.

Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway; Department of Anaesthesia and Intensive Care Medicine, St.Olav Hospital, Trondheim, Norway.

During paediatric cardiopulmonary resuscitation (CPR), patients may transition between pulseless electrical activity (PEA), asystole, ventricular fibrillation/tachycardia (VF/VT), and return of spontaneous circulation (ROSC). The aim of this study was to quantify the dynamic characteristics of this process.

Methods: ECG recordings were collected in patients who received CPR at the Children's Hospital of Philadelphia (CHOP) between 2006 and 2013. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03009572183093
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http://dx.doi.org/10.1016/j.resuscitation.2019.01.006DOI Listing
January 2019
3 Reads

Association of health insurance with post-resuscitation care and neurological outcomes after return of spontaneous circulation in out-of-hospital cardiac arrest patients in Korea.

Resuscitation 2019 Jan 9;135:176-182. Epub 2019 Jan 9.

Laboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.

Background: We investigated the association of health insurance status with post-resuscitation care and neurological recovery in out-of-hospital cardiac arrest (OHCA) and whether the effects changed with age or gender.

Methods: Adult OHCAs with presumed cardiac etiology who had sustained ROSC from 2013 to 2016 were enrolled from the nationwide OHCA registry of Korea. Insurance status was categorized into 2 groups: National Health Insurance (NHI) and Medical Aid (MA). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03009572183074
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http://dx.doi.org/10.1016/j.resuscitation.2018.12.023DOI Listing
January 2019
2 Reads

The effect of dispatcher-assisted cardiopulmonary resuscitation on early defibrillation and return of spontaneous circulation with survival.

Resuscitation 2019 Jan 9;135:21-29. Epub 2019 Jan 9.

Laboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Research Institute, Seoul, Republic of Korea; Department of Emergency Medicine, Dongkuk University Ilsan Hospital, Republic of Korea. Electronic address:

Background: Dispatcher-assisted cardiopulmonary resuscitation (DA-CPR) programs are implemented to augment bystander CPR and improve outcomes of patients with out-of-hospital cardiac arrest (OHCA). To understand the pathway of how DA-CPR improves outcomes of OHCA, we aimed to evaluate the effect of DA-CPR on defibrillation and return of spontaneous circulation (ROSC) with survival to hospital discharge within 90 min.

Methods: We conducted a population-based observational study of all adults with OHCA with presumed cardiac aetiology treated by emergency medical services (EMS) between 2013 and 2016, using a national OHCA registry. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.004DOI Listing
January 2019
2 Reads

North American validation of the Bokutoh criteria for withholding professional resuscitation in non-traumatic out-of-hospital cardiac arrest.

Resuscitation 2019 Jan 9;135:51-56. Epub 2019 Jan 9.

Department of Emergency Medicine, University of British Columbia, British Columbia, Canada; St. Paul's Hospital, Vancouver, British Columbia, Canada.

Background: Certain subgroups of patients with out-of-hospital cardiac arrest (OHCA) may not benefit from treatment. Early identification of this cohort in the prehospital (EMS) setting prior to any resuscitative efforts would prevent futile medical therapy and more appropriately allocate EMS and hospital resources. We sought to validate a clinical criteria from Bokutoh, Japan that identified a subgroup of OHCAs for whom withholding resuscitation may be appropriate. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.008DOI Listing
January 2019

Cardiopulmonary resuscitation performed by off-duty medical professionals versus laypersons and survival from out-of-hospital cardiac arrest among adult patients.

Resuscitation 2019 Jan 9;135:66-72. Epub 2019 Jan 9.

Kyoto University Health Service, Yoshida-Honmachi, Sakyo-ku, Kyoto, 606-8501, Japan.

Background: Cardiopulmonary resuscitation (CPR) performed by bystanders is a key factor for out-of-hospital cardiac arrest (OHCA) survival. This study aimed to evaluate the relationship between CPR performed by off-duty medical professionals vs. laypersons and one-month survival with favorable neurological outcome after OHCA. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.005DOI Listing
January 2019

Extensive cardiopulmonary resuscitation of preterm neonates at birth and mortality and developmental outcomes.

Resuscitation 2019 Jan 7;135:57-65. Epub 2019 Jan 7.

Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada; Alberta Health Services, Calgary, Alberta, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Canada; Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada. Electronic address:

Objective: To compare mortality and neurodevelopmental outcomes of extremely low gestational age neonates who received delivery room extensive cardiopulmonary resuscitation (DR-CPR) to those who did not require DR-CPR.

Methods: Preterm neonates born at <29 weeks' gestational age between January 2010 and September 2011 and assessed at Canadian Neonatal Follow-Up Network centers were studied. Neonates who received DR-CPR were compared to those who did not require DR-CPR using univariate and multivariable analyses. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03009572183100
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http://dx.doi.org/10.1016/j.resuscitation.2019.01.003DOI Listing
January 2019
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A comparison of non-invasive versus invasive measures of intracranial pressure in hypoxic ischaemic brain injury after cardiac arrest.

Resuscitation 2019 Jan 7. Epub 2019 Jan 7.

Division of Critical Care Medicine, Department of Medicine, Vancouver General Hospital, The University of British Columbia, Vancouver, BC, Canada.

Aim: Increased intracranial pressure (ICP) in hypoxic ischaemic brain injury (HIBI) can cause secondary ischaemic brain injury and culminate in brain death. Invasive ICP monitoring is limited by associated risks in HIBI patients. We sought to evaluate the agreement between invasive ICP measurements and non-invasive estimators of ICP (nICP) in HIBI patients. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.002DOI Listing
January 2019

Potential organ donors after Out-of-Hospital Cardiac Arrest during a ten-year period in Stockholm, Sweden.

Resuscitation 2019 Jan 7. Epub 2019 Jan 7.

Karolinska Institutet, Department of Medicine, Solna, Sweden; Center for Resuscitation Science, Stockholm, Sweden. Electronic address:

Background: Donation after brain death (DBD) is current praxis in Sweden. Circulatory death is far more common. Donation from patients suffering Out-of-Hospital Cardiac Arrest (OHCA) may have the potential to increase the organ-donor pool. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.001DOI Listing
January 2019

Are changes in objective observations or the patient's subjective feelings the day after admission the best predictors of in-hospital mortality? An observational study in a low-resource sub-Saharan hospital.

Resuscitation 2018 Oct 26;135:130-136. Epub 2018 Oct 26.

Department of Emergency Medicine, Hospital of South West Jutland, Esbjerg, Denmark.

Background: The first clinical re-assessment after admission to hospital probably provides the best opportunity to detect clinical deterioration or failure to improve, and decide if care should be intensified.

Aim: Compare changes the day after admission in the patient's subjective feelings and objective findings that included age, gender, the National Early Warning Score (NEWS) on admission, gait stability and mid-upper arm circumference (MUAC) on admission, and changes in NEWS, gait stability and mental alertness.

Setting: Acutely ill medical patients admitted to a low-resource sub-Saharan hospital. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2018.10.023DOI Listing
October 2018

Effect of mild hypercapnia on outcome and histological injury in a porcine post cardiac arrest model.

Resuscitation 2018 Oct 26;135:110-117. Epub 2018 Oct 26.

Division of Intensive Care, Department of Anaesthesiology, Intensive Care and Pain Medicine, Helsinki University Hospital and University of Helsinki, Finland; Emergency Medicine and Services, Helsinki University Hospital and Department of Emergency Medicine, University of Helsinki, Finland. Electronic address:

Aim Of The Study: To evaluate in an established porcine post cardiac arrest model the effect of a mild hypercapnic ventilatory strategy on outcome.

Methods: The left anterior descending coronary artery was occluded in 14 pigs and ventricular fibrillation induced and left untreated for 12 min. Cardiopulmonary resuscitation was performed for 5 min prior to defibrillation. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2018.10.024DOI Listing
October 2018
2 Reads

Double sequential external defibrillation for refractory ventricular fibrillation out-of-hospital cardiac arrest: A systematic review and meta-analysis.

Resuscitation 2018 Oct 26;135:124-129. Epub 2018 Oct 26.

Centre for Research and Evaluation, Ambulance Victoria, Doncaster, Victoria, Australia; Department of Community Emergency Health and Paramedic Practice, Monash University, Frankston, Victoria, Australia; Department of Epidemiology and Preventive Medicine, Monash University, Prahran, Victoria, Australia.

Background: Double sequential external defibrillation (DSED) is a novel intervention which has shown potential in the management of refractory ventricular fibrillation (VF). This review aims to identify the literature surrounding the use of DSED in out-of-hospital refractory VF and assess whether this intervention improves survival outcomes.

Methods: The databases Ovid Medline, EMBASE, CINAHL, SCOPUS and the Cochrane Library were searched from their commencement to January 29th 2018. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2018.10.025DOI Listing
October 2018
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Study on the timing of severe blood-brain barrier disruption using cerebrospinal fluid-serum albumin quotient in post cardiac arrest patients treated with targeted temperature management.

Resuscitation 2018 Oct 26;135:118-123. Epub 2018 Oct 26.

Department of Radiology, Chungnam National University Hospital, 282, Munhwa-ro, Jung-gu, Daejeon, Republic of Korea; Department of Radiology, College of Medicine, Chungnam National University School of Medicine, 282, Mokdong-ro, Jung-gu, Daejeon, Republic of Korea.

Aim: We aimed to evaluate the onset of severe blood-brain barrier (BBB) disruption using cerebrospinal fluid/serum albumin quotient (Qa) in cardiac arrest patients treated with target temperature management (TTM).

Methods: This was a prospective single-centre observational cohort study from October 2017 to September 2018 with the primary endpoint being the onset of severe BBB disruption, determined based on Qa in cardiac arrest patients treated with TTM. Enrolled patients were grouped according to neurologically good and poor outcomes using the cerebral performance category (CPC) at 3 months after return of spontaneous circulation (ROSC). Read More

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http://dx.doi.org/10.1016/j.resuscitation.2018.10.026DOI Listing
October 2018

Preliminary experience with point-of-care EEG in post-cardiac arrest patients.

Resuscitation 2018 Dec 31;135:98-102. Epub 2018 Dec 31.

Department of Emergency Medicine, University of Pittsburgh, United States; Department of Critical Care Medicine, University of Pittsburgh, United States.

Objective: Abnormal electroencephalography (EEG) patterns are common after resuscitation from cardiac arrest and have clinical and prognostic importance. Bedside continuous EEGs are not available in many institutions. We tested the feasibility of using a point-of-care system for EEG acquisition. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2018.12.022DOI Listing
December 2018
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