3,477 results match your criteria Respirology[Journal]


Letter from Greece.

Respirology 2019 Apr 22. Epub 2019 Apr 22.

Associate Professor of Respiratory Medicine, University of Ioannina, Ioannina, Greece.

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http://dx.doi.org/10.1111/resp.13568DOI Listing

Not just the common cold: Rhinovirus infection in lung allograft recipients.

Respirology 2019 Apr 19. Epub 2019 Apr 19.

National Heart and Lung Institute, Imperial College London, London, UK.

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http://dx.doi.org/10.1111/resp.13571DOI Listing

Practical approach to establishing pulmonary rehabilitation for people with non-COPD diagnoses.

Respirology 2019 Apr 19. Epub 2019 Apr 19.

Discipline of Physiotherapy, La Trobe University, Melbourne, VIC, Australia.

Pulmonary rehabilitation is a core aspect in the management of patients with chronic respiratory diseases. This paper describes a practical approach to establishing pulmonary rehabilitation for patients with non-COPD diagnoses using examples from the interstitial lung disease (ILD), pulmonary hypertension (PH), bronchiectasis and lung cancer patient populations. Aspects of pulmonary rehabilitation, including the rationale, patient selection, setting of programmes, patient assessment and training components (both exercise and non-exercise aspects), are discussed for these patient groups. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13562
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http://dx.doi.org/10.1111/resp.13562DOI Listing
April 2019
2 Reads

Sleep apnoea and immune regulation: The story is only beginning.

Respirology 2019 Apr 19. Epub 2019 Apr 19.

Department of Medicine, University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1111/resp.13565DOI Listing

Bronchiolitis obliterans syndrome as manifestation of lung GVHD: Not the only one - Reply.

Respirology 2019 Apr 19. Epub 2019 Apr 19.

Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1111/resp.13566DOI Listing

Bronchiolitis obliterans syndrome as manifestation of lung GVHD: Not the only one.

Respirology 2019 Apr 19. Epub 2019 Apr 19.

Division of Respirology, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/resp.13567DOI Listing

Does ISWT evaluate maximal exercise capacity in subjects with severe asthma?

Respirology 2019 Apr 17. Epub 2019 Apr 17.

Department of Physical Therapy, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13563
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http://dx.doi.org/10.1111/resp.13563DOI Listing
April 2019
2 Reads

Azithromycin reduces airway inflammation induced by human rhinovirus in lung allograft recipients.

Respirology 2019 Apr 15. Epub 2019 Apr 15.

Telethon Kids Institute, Centre for Health Research, The University of Western Australia, Perth, WA, Australia.

Background And Objective: Human rhinovirus (RV) is a common upper and lower respiratory pathogen in lung allograft recipients causing respiratory tract exacerbation and contributing towards allograft dysfunction and long-term lung decline. In this study, we tested the hypothesis that RV could infect both the small and large airways, resulting in significant inflammation.

Methods: Matched large and small airway epithelial cells (AEC) were obtained from five lung allograft recipients. Read More

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http://dx.doi.org/10.1111/resp.13550DOI Listing
April 2019
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What's in the CART? A decision rule to predict short-term mortality during COPD exacerbations.

Authors:
Don D Sin

Respirology 2019 Apr 15. Epub 2019 Apr 15.

UBC Centre for Heart Lung Innovation (HLI), St. Paul's Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1111/resp.13561DOI Listing
April 2019
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Emerging respiratory infections threatening public health in the Asia-Pacific region: A position paper of the Asian Pacific Society of Respirology.

Respirology 2019 Apr 15. Epub 2019 Apr 15.

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.

In past decades, we have seen several epidemics of respiratory infections from newly emerging viruses, most of which originated in animals. These emerging infections, including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV) and the pandemic influenza A(H1N1) and avian influenza (AI) viruses, have seriously threatened global health and the economy. In particular, MERS-CoV and AI A(H7N9) are still causing infections in several areas, and some clustering of cases of A(H5N1) and A(H7N9) may imply future possible pandemics. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13558
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http://dx.doi.org/10.1111/resp.13558DOI Listing
April 2019
2 Reads

Associations between lung and endothelial function in early middle age.

Respirology 2019 Apr 15. Epub 2019 Apr 15.

Firestone Institute for Respiratory Health, Michael de Groote School of Medicine, McMaster University and St Joseph's Healthcare, Hamilton, ON, Canada.

Background And Objective: Chronic lung disease is associated with impaired endothelial function and this may be a risk factor for poor cardiovascular health. It is unknown if there is an association between lung and endothelial function in the general population. We investigated associations between lung and endothelial function in a population-based cohort of 38-year-old men and women. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13556
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http://dx.doi.org/10.1111/resp.13556DOI Listing
April 2019
2 Reads

BMPR2-expressing bone marrow-derived endothelial-like progenitor cells alleviate pulmonary arterial hypertension in vivo.

Respirology 2019 Apr 12. Epub 2019 Apr 12.

Department of Thoracic Medicine, Royal Adelaide Hospital, Adelaide, SA, Australia.

Background And Objective: Pulmonary arterial hypertension (PAH) is characterized by increased resistance in the distal pulmonary arteries, ultimately leading to right heart failure and, despite the available therapeutics, survival remains poor. Reduced expression of bone morphogenetic protein receptor type 2 (BMPR2) is strongly associated with PAH. Cell therapies are of interest in PAH, but whether this approach can upregulate BMPR2 is not known. Read More

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http://dx.doi.org/10.1111/resp.13552DOI Listing
April 2019
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Multidisciplinary team working for vocal cord dysfunction: Now it's GO time.

Authors:
James H Hull

Respirology 2019 Apr 11. Epub 2019 Apr 11.

Department of Respiratory Medicine, Royal Brompton Hospital, London, UK.

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http://dx.doi.org/10.1111/resp.13560DOI Listing
April 2019
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Hospitalizations for patients with acute respiratory exacerbations: In pursuit of rest or recovery?

Respirology 2019 Apr 9. Epub 2019 Apr 9.

Department of Physiotherapy, Monash University, Melbourne, VIC, Australia.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13555
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http://dx.doi.org/10.1111/resp.13555DOI Listing
April 2019
3 Reads

Osteopontin lung gene expression is a marker of disease severity in pulmonary arterial hypertension.

Respirology 2019 Apr 8. Epub 2019 Apr 8.

Toronto Lung Transplant Program, University of Toronto, Toronto, ON, Canada.

Background And Objective: Osteopontin (OPN) is a pleiotropic cytokine involved in the proliferation of pulmonary artery smooth muscle cells (PA-SMC). OPN is upregulated in the lungs of patients with pulmonary hypertension (PH) associated with pulmonary fibrosis, suggesting that the lung is a source of OPN. We hypothesized that OPN lung expression is elevated in Group I pulmonary arterial hypertension (PAH) and is correlated to haemodynamics. Read More

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http://dx.doi.org/10.1111/resp.13557DOI Listing
April 2019
1 Read

Letter from Italy.

Authors:
Alberto Papi

Respirology 2019 Apr 8. Epub 2019 Apr 8.

Research Center on Asthma and COPD, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1111/resp.13554DOI Listing

Airway distensibility: Bringing physiology to the bedside.

Authors:
Andrew Wellman

Respirology 2019 Apr 3. Epub 2019 Apr 3.

Sleep Disordered Breathing Lab, Brigham and Women's Hospital, Boston, MA, USA.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13551
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http://dx.doi.org/10.1111/resp.13551DOI Listing
April 2019
1 Read

Contemporary Concise Review 2018: Asthma and chronic obstructive pulmonary disease.

Authors:
John W Upham

Respirology 2019 Apr 3. Epub 2019 Apr 3.

Princess Alexandra Hospital, The University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1111/resp.13553DOI Listing
April 2019
2 Reads

Airway distensibility: Bringing physiology to the bedside - Reply.

Respirology 2019 Apr 3. Epub 2019 Apr 3.

Sleep Center, Department of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13548
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http://dx.doi.org/10.1111/resp.13548DOI Listing
April 2019
2 Reads

Nocturnal hypoxaemia is associated with adverse outcomes in interstitial lung disease.

Respirology 2019 Apr 1. Epub 2019 Apr 1.

Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Sydney, NSW, Australia.

Background And Objective: Sleep-disordered breathing (SDB) has been reported as highly prevalent in idiopathic pulmonary fibrosis (IPF) and other interstitial lung disease (ILD) populations. Nocturnal oxygen desaturation (NOD), or the total sleep time spent with SpoO < 90% (TST < 90), can occur both with and without associated apnoeas, and is common in ILD. This study aimed to characterize abnormal SDB and extent of TST < 90 in ILD patients and evaluate relationships between TST < 90 and markers of disease severity, development of pulmonary hypertension (PH) and mortality. Read More

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http://dx.doi.org/10.1111/resp.13549DOI Listing
April 2019
3 Reads

Contemporary Concise Review 2018: Respiratory infections and tuberculosis.

Respirology 2019 Mar 30. Epub 2019 Mar 30.

Stanley Ho Center for Emerging Infectious Diseases, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.

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http://dx.doi.org/10.1111/resp.13542DOI Listing
March 2019
1 Read

Eligibility for anti-fibrotic treatment in idiopathic pulmonary fibrosis depends on the predictive equation used for pulmonary function testing.

Respirology 2019 Mar 28. Epub 2019 Mar 28.

Respiratory Department, John Hunter Hospital (JHH), Newcastle, NSW, Australia.

Background And Objective: Publicly funded therapy for idiopathic pulmonary fibrosis (IPF) relies on percentage predicted values from pulmonary function testing, for example Australian patients must have a forced vital capacity ≥50% (%FVC), transfer factor of the lung for carbon monoxide ≥ 30% (%TLco) and forced expiratory volume in 1 s (FEV )/FVC ratio > 0.7. Despite defined cut-off values, no jurisdiction prescribes a reference equation for use; multiple equations exist. Read More

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http://dx.doi.org/10.1111/resp.13540DOI Listing
March 2019
2 Reads

Transmission of bacteria in bronchiectasis and chronic obstructive pulmonary disease: Low burden of cough aerosols.

Respirology 2019 Mar 27. Epub 2019 Mar 27.

Lung Bacteria Group, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.

Background And Objective: Aerosol transmission of Pseudomonas aeruginosa has been suggested as a possible mode of respiratory infection spread in patients with cystic fibrosis (CF); however, whether this occurs in other suppurative lung diseases is unknown. Therefore, we aimed to determine if (i) patients with bronchiectasis (unrelated to CF) or chronic obstructive pulmonary disease (COPD) can aerosolize P. aeruginosa during coughing and (ii) if genetically indistinguishable (shared) P. Read More

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http://dx.doi.org/10.1111/resp.13544DOI Listing
March 2019
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Azithromycin and ABBA in the chest clinic: 'The winner takes it all...'

Authors:
Peter G Gibson

Respirology 2019 Mar 27. Epub 2019 Mar 27.

Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, NSW, Australia.

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http://dx.doi.org/10.1111/resp.13545DOI Listing
March 2019
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Transbronchial evaluation of peripheral pulmonary lesions using ultrasonic spectrum analysis in lung cancer patients.

Respirology 2019 Mar 25. Epub 2019 Mar 25.

Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.

Background And Objective: Analysis of the endobronchial ultrasound (EBUS) radiofrequency spectrum has been used for convex-probe EBUS technology. Quantitative imaging analysis is also warranted for guided bronchoscopy using radial-probe EBUS (RP-EBUS) targeting peripheral pulmonary lesions (PPL). This study aimed to determine the feasibility of radiofrequency spectrum analysis for distinguishing malignant and benign PPL during diagnostic bronchoscopy. Read More

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http://dx.doi.org/10.1111/resp.13534DOI Listing

Endobronchial ultrasound-guided transbronchial needle aspiration in sarcoidosis: Beyond the diagnostic yield.

Respirology 2019 Mar 25. Epub 2019 Mar 25.

Department of Pulmonary Medicine, Cleveland Clinic, Cleveland, OH, USA.

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the commonly used technique for pathological confirmation of clinically suspected sarcoidosis, mostly owing to its consistently high success rate in the detection of granulomas. However, other possible advantages, which are less appreciated and often poorly studied, may also contribute to the wider use of EBUS-TBNA in the future. These advantages include refinement of differential diagnoses through the study of lymph node characteristics during B-mode examination; reduction of complications associated with bronchoscopy, as well as improved triage of the specimen for ancillary studies with the use of rapid on-site evaluation; optimization of the quality of the sample through the selection of a target area for biopsy with minimal vascularity and absence of calcifications by using the colour Doppler and the B-mode; and prediction of the presence of extensive lymph node fibrosis by using the strain elastography module. Read More

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http://dx.doi.org/10.1111/resp.13537DOI Listing
March 2019
2 Reads

NIV in amyotrophic lateral sclerosis: The 'when' and 'how' of the matter.

Respirology 2019 Mar 25. Epub 2019 Mar 25.

INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Sorbonne Université, Paris, France.

Non-invasive ventilation (NIV) has become an essential part of the treatment of amyotrophic lateral sclerosis (ALS) since 2006. NIV very significantly improves survival, quality of life and cognitive performances. The initial NIV settings are simple, but progression of the disease, ventilator dependence and upper airway involvement sometimes make long-term adjustment of NIV more difficult, with a major impact on survival. Read More

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http://dx.doi.org/10.1111/resp.13525DOI Listing
March 2019
1 Read

How best to assess cough as an outcome measure.

Respirology 2019 Mar 25. Epub 2019 Mar 25.

The Pulmonary, Allergy, and Critical Care Medicine Division, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.

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http://dx.doi.org/10.1111/resp.13541DOI Listing

Metabolomics in chronic lung diseases.

Respirology 2019 Mar 25. Epub 2019 Mar 25.

School of Medicine, University of Western Australia, Perth, WA, Australia.

Chronic lung diseases represent a significant global burden. Their increasing incidence and complexity render a comprehensive, multidisciplinary and personalized approach to each patient, critically important. Most recently, unique biochemical pathways and disease markers have been identified through large-scale metabolomic studies. Read More

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http://dx.doi.org/10.1111/resp.13530DOI Listing
March 2019
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Epithelial cell adhesion molecule (EpCAM) from pleural fluid cell lysates is a highly accurate diagnostic biomarker of adenocarcinomatous effusions.

Respirology 2019 Mar 22. Epub 2019 Mar 22.

Research Group of Cancer Biomarkers, IRBLleida, Lleida, Spain.

Background And Objective: The discovery of highly accurate pleural fluid (PF) biomarkers of malignancy remains elusive. We assessed the operating characteristics of the PF epithelial cell adhesion molecule (EpCAM), claudin 4 (CL4) and human epididymis protein 4 (HE4) as potential markers of epithelial malignancies.

Methods: The three markers were quantified by immunoassays in the supernatants (s) and cell lysates (cl) of 175 PF samples. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13539
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http://dx.doi.org/10.1111/resp.13539DOI Listing
March 2019
4 Reads

Airways wide shut: A physiological phenotype of asthma?

Authors:
Claude S Farah

Respirology 2019 Mar 22. Epub 2019 Mar 22.

Department of Thoracic Medicine, Concord Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.1111/resp.13533DOI Listing

Letter from France: How structures condition outputs.

Authors:
Nicolas Roche

Respirology 2019 May 22;24(5):492-493. Epub 2019 Mar 22.

President of Société de Pneumologie de Langue Française, Respiratory Medicine, Cochin Hospital, University Paris Descartes, Paris, France.

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http://dx.doi.org/10.1111/resp.13535DOI Listing

Risk stratification for short-term mortality at hospital admission for acute exacerbations of COPD.

Respirology 2019 Mar 21. Epub 2019 Mar 21.

Department of Respiratory Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.

Background And Objective: Exacerbations of chronic obstructive pulmonary disease (ECOPD) are associated with increased in-hospital and short-term mortality. Developing an easy-to-use model to predict adverse outcomes will be useful in daily clinical practice and will facilitate management decisions. We aimed to assess mortality rates and potential predictors for short-term mortality after severe ECOPD. Read More

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http://dx.doi.org/10.1111/resp.13538DOI Listing
March 2019
2 Reads

Tuberculous mediastinal lymphadenopathy: Reaching the target.

Respirology 2019 Mar 21. Epub 2019 Mar 21.

Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.

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http://dx.doi.org/10.1111/resp.13536DOI Listing
March 2019
2 Reads

Obesity and the lungs: Not just a crush.

Respirology 2019 Mar 21. Epub 2019 Mar 21.

Department of Respiratory Medicine, Royal North Shore Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.1111/resp.13532DOI Listing
March 2019
3 Reads

Maintaining the benefits following pulmonary rehabilitation: Achievable or not?

Respirology 2019 Mar 19. Epub 2019 Mar 19.

Faculty of Health Sciences, The University of Sydney, Sydney, NSW, Australia.

Pulmonary rehabilitation (PR) improves exercise capacity, health-related quality of life (HRQoL) and dyspnoea in patients with COPD and other lung conditions. Once PR is completed, the benefits gained begin to decline unless patients continue to exercise regularly. Due to limited evidence in other lung conditions, this review aims to examine the current evidence regarding maintenance exercise programmes for patients with COPD and to determine the types of programmes that are able to maintain the benefits gained from PR to 12 months and longer. Read More

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http://dx.doi.org/10.1111/resp.13518DOI Listing
March 2019
1 Read

Treatment of interstitial lung disease: Do the ends justify the means?

Authors:
Daniel J Kass

Respirology 2019 Mar 19. Epub 2019 Mar 19.

Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/resp.13526DOI Listing
March 2019
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Why are people with asthma susceptible to pneumonia? A review of factors related to upper airway bacteria.

Respirology 2019 May 18;24(5):423-430. Epub 2019 Mar 18.

Respiratory Medicine, Sir Charles Gairdner Hospital, Perth, WA, Australia.

Asthma and pneumonia are common respiratory conditions globally, affecting individuals of all ages. Streptococcus pneumoniae is the predominant bacterial cause of pneumonia, with nasopharyngeal carriage an important step towards invasive and pulmonary disease. Vaccines provide individual protection, and also prevent nasopharyngeal carriage, providing herd immunity. Read More

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http://dx.doi.org/10.1111/resp.13528DOI Listing
May 2019
2 Reads

Understanding the measurement properties of the incremental shuttle walk test in patients with severe asthma.

Respirology 2019 Mar 18. Epub 2019 Mar 18.

Centre for Exercise Rehabilitation Science, Respiratory Sciences, Leicester, UK.

Background And Objective: We investigated the repeatability and validity of the incremental shuttle walk test (ISWT) distance compared to peak oxygen uptake (VO ) during maximal incremental cycle ergometer (ICE) and treadmill (ITM) tests in adults with severe asthma.

Methods: Adults with severe asthma, Medical Research Council (MRC) dyspnoea ≥2, were recruited from specialists caring for patients with severe asthma. All participants performed three ISWT (familiarization and two subsequent tests on the same day), an ICE and an ITM in a randomized order, on separate days, to intolerance with expiratory gas analysis. Read More

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http://dx.doi.org/10.1111/resp.13519DOI Listing
March 2019
4 Reads

Novel endosomal NOX2 oxidase inhibitor ameliorates pandemic influenza A virus-induced lung inflammation in mice.

Respirology 2019 Mar 18. Epub 2019 Mar 18.

School of Health Sciences and Biomedical Sciences, RMIT University, Melbourne, VIC, Australia.

Background And Objective: Influenza A viruses (IAV) cause respiratory tract infections that can be fatal when the virus spreads to the alveolar space (i.e. alveolitis), and this is mainly observed with highly pathogenic strains. Read More

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http://dx.doi.org/10.1111/resp.13524DOI Listing
March 2019
1 Read

Multidisciplinary team clinic for vocal cord dysfunction directs therapy and significantly reduces healthcare utilization.

Respirology 2019 Mar 18. Epub 2019 Mar 18.

Monash Lung and Sleep, Monash University and Hospital, Melbourne, Victoria, Australia.

Background And Objective: Multidisciplinary team (MDT) clinics use an integrated approach to individualize care of complex medical conditions. Vocal cord dysfunction (VCD) is a challenging condition that is likely to benefit from MDT clinics but this has not been researched.

Methods: A prospective observational cohort study of a novel VCD MDT clinic was conducted in patients with suspected VCD. Read More

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http://dx.doi.org/10.1111/resp.13520DOI Listing
March 2019
2 Reads

Predicting which children have asthma: Are we any closer to finding the Holy Grail?

Authors:
Peter D Sly

Respirology 2019 Mar 18. Epub 2019 Mar 18.

Children's Health and Environment Program, The University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1111/resp.13529DOI Listing

Applications of CRISPR systems in respiratory health: Entering a new 'red pen' era in genome editing.

Respirology 2019 Mar 18. Epub 2019 Mar 18.

Faculty of Science, School of Human Sciences and School of Agriculture and Environment, The University of Western Australia, Perth, WA, Australia.

Respiratory diseases, such as influenza infection, acute tracheal bronchitis, pneumonia, tuberculosis, chronic obstructive pulmonary disease, asthma, lung cancer and nasopharyngeal carcinoma, continue to significantly impact human health. Diseases of the lung and respiratory tract are influenced by environmental conditions and socio-economic factors; however, many of these serious respiratory disorders are also rooted in genetic or epigenetic causes. Clustered regularly interspaced palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins, isolated from the immune system of prokaryotes, provide a tool to manipulate gene sequences and gene expression with significant implications for respiratory research. Read More

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http://dx.doi.org/10.1111/resp.13527DOI Listing
March 2019
2 Reads

CORRIGENDUM.

Authors:

Respirology 2019 Apr 19;24(4):396. Epub 2019 Feb 19.

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http://dx.doi.org/10.1111/resp.13515DOI Listing
April 2019
1 Read

The past, present and future of pulmonary rehabilitation.

Respirology 2019 Mar 13. Epub 2019 Mar 13.

Department of Rehabilitation Sciences, KU Leuven - University of Leuven, Leuven, Belgium.

Abundant evidence supports the use of pulmonary rehabilitation as a treatment for stable and exacerbated chronic obstructive pulmonary disease. Several questions around the science base of rehabilitation in other patient groups as well as the role of rehabilitation as a component in other comprehensive care trajectories remain to be addressed. The impact of a rehabilitation programme could also perhaps be enhanced if clear guidance would be available on how to individualize the components of a rehabilitation programme in individual patients. Read More

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http://doi.wiley.com/10.1111/resp.13517
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http://dx.doi.org/10.1111/resp.13517DOI Listing
March 2019
19 Reads

Pulmonary artery enlargement predicts poor outcome during acute exacerbations of fibrotic interstitial lung disease.

Respirology 2019 Mar 13. Epub 2019 Mar 13.

Department of Respiratory Medicine, Kobe City Medical Centre General Hospital, Kobe, Japan.

Background And Objective: In fibrotic interstitial lung disease (f-ILD), pulmonary artery diameter to ascending aorta diameter ratio (PA/A) ≥ 1 during the stable stage is associated with worse outcomes; however, the effect of acute exacerbation (AE) on the PA/A is unknown.

Methods: Patients with a diagnosis of AE of f-ILD and with a computed tomography (CT) scan performed during stable period to confirm background fibrosis, as well as a CT scan at admission, were included. The pulmonary arterial diameter, ascending aortic diameter and PA/A were measured using CT during AE and CT prior to AE, when available, to evaluate the changes. Read More

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http://dx.doi.org/10.1111/resp.13504DOI Listing
March 2019
1 Read

Mechanism of benefit of non-invasive ventilation in COPD with hypercapnic respiratory failure.

Respirology 2019 May 8;24(5):494. Epub 2019 Mar 8.

Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1111/resp.13522DOI Listing
May 2019
1 Read

Mechanism of benefit of non-invasive ventilation in COPD with hypercapnic respiratory failure - Reply.

Respirology 2019 May 8;24(5):494-495. Epub 2019 Mar 8.

Department of Pulmonary Diseases/Home Mechanical Ventilation, University of Groningen, University Medical Center, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/resp.13523DOI Listing
May 2019
1 Read