Respir Physiol Neurobiol 2021 Jul 10;294:103740. Epub 2021 Jul 10.
Clinical Exercise & Respiratory Physiology Laboratory, Department of Kinesiology & Physical Education, McGill University, Montreal, Quebec, Canada; Translational Research in Respiratory Diseases Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada. Electronic address:
We tested the hypothesis that increasing the respiratory control systems' arterial PCO equilibrium point via induced acute metabolic alkalosis by ingestion of sodium bicarbonate (NaHCO, 0.3 g/kg) would decrease the ventilatory equivalent for CO (V̇/V̇CO) at its lowest point ("nadir") during constant-load cycle exercise testing performed at 80 % of peak power output in 18 healthy young adults. Compared to the sodium chloride (4 g) control condition, ingestion of NaHCO: increased arterialized venous pH, HCO- and PCO at rest by 0. Read More