1,128,364 results match your criteria Reproduction Fertility and Development[Journal]


Foraging Performance, Prosociality, and Kin Presence Do Not Predict Lifetime Reproductive Success in Batek Hunter-Gatherers.

Hum Nat 2018 Dec 14. Epub 2018 Dec 14.

Department of Anthropology, Dartmouth College, Hanover, NH, 03755, USA.

Identifying the determinants of reproductive success in small-scale societies is critical for understanding how natural selection has shaped human evolution and behavior. The available evidence suggests that status-accruing behaviors such as hunting and prosociality are pathways to reproductive success, but social egalitarianism may diminish this pathway. Here we introduce a mixed longitudinal/cross-sectional dataset based on 45 years of research with the Batek, a population of egalitarian rain forest hunter-gatherers in Peninsular Malaysia, and use it to test the effects of four predictors of lifetime reproductive success: (i) foraging return rate, (ii) sharing proclivity, (iii) cooperative foraging tendency, and (iv) kin presence. Read More

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December 2018

Proteins, transcripts, and genetic architecture of seminal fluid and sperm in the mosquito .

Mol Cell Proteomics 2018 Dec 14. Epub 2018 Dec 14.

Biology & Biochemistry, Syracuse University, United States of America

The yellow fever mosquito, , transmits several viruses causative of serious diseases, including dengue, Zika, and chikungunya. Some proposed efforts to control this vector involve manipulating reproduction to suppress wild populations or to replace them with disease-resistant mosquitoes. The design of such strategies requires an intimate knowledge of reproductive processes, yet our basic understanding of reproductive genetics in this vector remains largely incomplete. Read More

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December 2018
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Contrasting patterns of virus protection and functional incompatibility genes in two conspecific strains from .

Appl Environ Microbiol 2018 Dec 14. Epub 2018 Dec 14.

School of Biological Sciences, The University of Queensland, Brisbane, Australia

infections can present different phenotypes in hosts, including different forms of reproductive manipulation and antiviral protection, which may influence infection dynamics within host populations. In populations of two distinct strains co-exist, each manipulating host reproduction: PanCI, causes cytoplasmic incompatibility (CI), whereas PanMK, causes male-killing (MK). CI occurs when a -infected male mates with a female not infected with a compatible type of leading to non-viable offspring. Read More

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December 2018

Omics approaches to study juvenile hormone synthesis.

Curr Opin Insect Sci 2018 Oct 26;29:49-55. Epub 2018 May 26.

Department of Biological Sciences and Biomolecular Science Institute, Florida International University, Miami, FL, USA. Electronic address:

The juvenile hormones (JHs) are a family of insect acyclic sesquiterpenoids produced by the corpora allata (CA), a pair of endocrine glands connected to the brain. They are involved in the regulation of development, reproduction, behavior, caste determination, diapause, stress response, and numerous polyphenisms. In the post-genomics era, comprehensive analyses using functional 'omics' technologies such as transcriptomics, proteomics and metabolomics have increased our understanding of the activity of the minute CA. Read More

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October 2018

G protein-coupled receptors in arthropod vectors: omics and pharmacological approaches to elucidate ligand-receptor interactions and novel organismal functions.

Curr Opin Insect Sci 2018 Oct 26;29:12-20. Epub 2018 May 26.

Department of Electrical and Computer Engineering, TAMU, College Station, TX 77843-3128, United States.

Regulation of many physiological processes in animals, certainly those controlled by neuropeptide hormones, involves G protein-coupled receptors (GPCRs). Our work focusing on endocrine regulation of diuresis and water balance in mosquitoes and ticks started in 1997 with the kinin receptor, at the dawn of the omics era. After the genomic revolution, we began work on the endocrinology of reproduction in the red imported fire ant. Read More

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October 2018

The immediate sensorimotor effects of elbow orthoses in patients with lateral elbow tendinopathy: a prospective crossover study.

J Shoulder Elbow Surg 2019 Jan;28(1):e10-e17

Musculoskeletal Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address:

Background: Counterforce orthoses are used to manage lateral elbow tendinopathy, and their effectiveness in improving motor function has been documented. Little is known about the impact of bracing on sensory function. The objective of this study was to investigate the immediate effectiveness of 2 counterforce orthoses in improving the sensorimotor abilities of the hand in patients with lateral elbow tendinopathy. Read More

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January 2019

Sublethal and Hormesis Effects of Clothianidin on the Black Cutworm (Lepidoptera: Noctuidae).

J Econ Entomol 2018 Dec;111(6):2809-2816

College of Plant Protection, Shandong Agricultural University, 61 Daizong Street, Tai'an, Shandong, P.R. China.

The black cutworm, Agrotis ipsilon (Hufnagel) (Lepidoptera: Noctuidae), has been considered a major insect pest in China that causes damage to corn at the seeding stage. The present study measured the lethal and sublethal effects of the neonicotinoid insecticide clothianidin on A. ipsilon. Read More

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December 2018

Clipping of Basilar Perforator Pure Arterial Malformation Aneurysm: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2018 Dec 14. Epub 2018 Dec 14.

University of Miami, Department of Neurosurgery, Miami, Florida.

Pure arterial malformations are rarely-encountered intracranial lesions, often mistaken for arteriovenous malformations. A minority of these lesions may harbor associated aneurysms. In a recent series of 12 patients with pure arterial malformations, 3 patients had associated aneurysms. Read More

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December 2018

Responses of propagule germination and sexual reproduction of submerged macrophytes exposed to cadmium.

Chemosphere 2018 Dec 8;219:436-443. Epub 2018 Dec 8.

Key Laboratory of Aquatic Botany and Watershed Ecology, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, 430074, China; Hubei Key Laboratory of Wetland Evolution & Ecological Restoration, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, 430074, China. Electronic address:

Submerged macrophytes are considered the main primary producers in shallow lakes. Recently, they have experienced a decline due to increasing environmental impacts, e.g. Read More

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December 2018

Ostrich egg yolk improves post thaw quality and in vivo fertility of Nili Ravi buffalo (Bubalus bubalis) bull spermatozoa.

Theriogenology 2018 Dec 6;126:140-144. Epub 2018 Dec 6.

Semen Production Unit Qadirabad, Sahiwal, Pakistan. Electronic address:

Egg yolk containing higher ratio of phospholipids and cholesterol may have better cryoprotective effect to buffalo spermatozoa during cryopreservation. Our objectives were to ascertain the comparison of Ostrich and chicken egg yolk in semen extender on post thaw quality, motion dynamics and in vivo fertility of Nili Ravi buffalo (Bubalus bubalis) bull spermatozoa. Semen samples (n = 45) from five bulls were collected once a week for a period of nine weeks and diluted in Triladyl extender having different concentrations of Ostrich egg yolk (10%, 15%, 20%) and 20% chicken egg yolk as control at 37 °C. Read More

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December 2018

Risk of Chlamydia abortus transmission via embryo transfer using in vitro produced early bovine embryos.

Theriogenology 2018 Dec 1;126:114-120. Epub 2018 Dec 1.

LUNAM University, Oniris, Nantes-Atlantic National College of Veterinary Medicine, Food Science and Engineering, Sanitary Security of Reproduction Biotechnology Unit, Nantes, France. Electronic address:

The objectives of this study were to determine (i) whether Chlamydia (C.) abortus would adhere to the intact zona pellucida (ZP-intact) of early in vitro produced bovine embryos; (ii) whether the bacteria would adhere to the embryos (ZP-free) after in vitro infection; and (iii) the efficacy of the International Embryo Transfer Society (IETS) washing protocol. The experimentation was made twice. Read More

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December 2018

Early-life exposure to the endocrine disruptor 17-α-ethinylestradiol induces delayed effects in adult brain, liver and ovotestis proteomes of a self-fertilizing fish.

J Proteomics 2018 Dec 11. Epub 2018 Dec 11.

Laboratory of Evolutionary and Adaptive Physiology - Institute of Life, Earth and Environment - University of Namur, 61 Rue de Bruxelles, B5000 Namur, Belgium.

Early-life represents a critically sensitive window to endocrine disrupting chemicals, potentially leading to long-term repercussions on the phenotype later in life. The mechanisms underlying this phenomenon, referred to as the Developmental Origins of Health and Disease (DOHaD), are still poorly understood. To gain molecular understanding of these effects, we exposed mangrove rivulus (Kryptolebias marmoratus) for 28 days post hatching (dph) to 4 and 120 ng/L 17-α-ethinylestradiol, a model xenoestrogen. Read More

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December 2018

Osseointegrated Percutaneous Prosthetic System for the Treatment of Patients With Transfemoral Amputation: A Prospective Five-year Follow-up of Patient-reported Outcomes and Complications.

J Am Acad Orthop Surg 2018 Dec 13. Epub 2018 Dec 13.

From the Centre for Advanced Reconstruction of Extremities (C.A.R.E.), Sahlgrenska University Hospital, Department of Orthopaedics, Institute for Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden (Dr. Brånemark, Dr. Hagberg, Mrs. Kulbacka-Ortiz, and Dr. Berlin), International Centre for Osseointegration Research, Education and Surgery (iCORES), Department of Orthopaedics, University of California, San Francisco, CA (Dr. Brånemark), and the Sahlgrenska University Hospital, Department of Orthopaedics, Institute for Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden (Dr. Rydevik).

Introduction: Direct skeletal attachment of prostheses has previously been shown to improve patient-reported outcome (PRO) measures of individuals with transfemoral amputation (TFA) at 2-year follow-up. This prospective study reports the outcomes at 5-year follow-up.

Methods: A total of 51 patients (55 legs) with TFA were included in a prospective study. Read More

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December 2018

[Modern ethiotropic chemotherapy of human cytomegalovirus infection: clinical effectiveness, molecular mechanism of action, drug resistance, new trends and prospects. Part 1.]

Authors:
V L Andronova

Vopr Virusol 2018 ;63(5):202-211

National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya, Moscow, 123098, Russian Federation.

Modern chemotherapy of cytomegalovirus (CMV) infections has a very limited arsenal of first-line drugs. These are preparations of ganciclovir (GCV) belonging to the class of modified nucleosides and its metabolic precursor ganciclovir valine ester. After three-step phosphorylation, GCV, as a structural analogue of the natural nucleotide, competes with it for binding to DNA polymerase and, due to its structural features, inhibits its activity. Read More

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January 2018

Type I IFNs in the female reproductive tract: The first line of defense in an ever-changing battleground.

J Leukoc Biol 2018 Dec 14. Epub 2018 Dec 14.

Department of Medical Gerontology, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.

The primary function of the female reproductive tract (FRT) is to enable successful reproduction, yet the biologic mechanisms required to accomplish this, which include fluctuating sex hormones and tolerance of semen and a semi-allogeneic fetus, can leave this unique mucosal environment susceptible to pathogenic challenge. Consequently, the FRT has evolved specialized innate and adaptive immune responses tailored to protecting itself from infection without compromising reproductive success. A family of innate immune cytokines that has emerged as important regulators of these immune responses is the type I IFNs. Read More

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December 2018

The serine protease testisin is present on the surface of capacitated stallion spermatozoa and interacts with key zona pellucida binding proteins.

Andrology 2018 Dec 13. Epub 2018 Dec 13.

Priority Research Centre for Reproductive Science, University of Newcastle, Callaghan, NSW, Australia.

Background And Objectives: Serine proteases are emerging as important players in the spermatozoon's acquisition of functional competence. This study aimed to characterize the serine protease testisin (PRSS21) in stallion spermatozoa, examining its surface expression, possible origins in the testis and epididymis, and changes in response to capacitation and acrosome reaction, as well as its capacity to form high molecular weight complexes and interact with other proteins.

Materials And Methods: The role of serine proteases in spontaneous capacitation and acrosome reaction of stallion spermatozoa was established using the serine protease inhibitor, AEBSF. Read More

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December 2018

The omnivorous predator Macrolophus pygmaeus, a good candidate for the control of both greenhouse whitefly and poinsettia thrips on gerbera plants.

Insect Sci 2018 Dec 13. Epub 2018 Dec 13.

Wageningen University & Research, BU Greenhouse Horticulture, PO Box 20, 2265, ZG, Bleiswijk, The Netherlands.

The poinsettia thrips Echinothrips americanus Morgan is a relatively new pest that has spread rapidly worldwide and causes serious damage in both vegetable and ornamental plants. In this study, we investigated if and how effective this pest can be controlled in gerbera by the omnivorous predator Macrolophus pygmaeus (Rambur). Because herbivores on plants can interact through a shared predator, we also investigated how poinsettia thrips control is affected by the presence of the greenhouse whitefly Trialeurodes vaporariorum (Westwood), a pest that commonly co-exists with E. Read More

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December 2018

RanGAP-mediated nucleocytoplasmic transport of Prospero regulates neural stem cell lifespan in Drosophila larval central brain.

Aging Cell 2018 Dec 13:e12854. Epub 2018 Dec 13.

Division of Human Reproduction and Developmental Genetics, The Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

By the end of neurogenesis in Drosophila pupal brain neuroblasts (NBs), nuclear Prospero (Pros) triggers cell cycle exit and terminates NB lifespan. Here, we reveal that in larval brain NBs, an intrinsic mechanism facilitates import and export of Pros across the nuclear envelope via a Ran-mediated nucleocytoplasmic transport system. In rangap mutants, the export of Pros from the nucleus to cytoplasm is impaired and the nucleocytoplasmic transport of Pros becomes one-way traffic, causing an early accumulation of Pros in the nuclei of the larval central brain NBs. Read More

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December 2018
6.340 Impact Factor

Ecological differentiation facilitates fine-scale coexistence of sexual and asexual Boechera.

Am J Bot 2018 Dec 13. Epub 2018 Dec 13.

Department of Biology, Duke University, Box 90338, Durham, North Carolina, 27708, USA.

Premise Of The Study: Ecological differentiation (ED) between sexual and asexual organisms may permit the maintenance of reproductive polymorphism. Several studies of sexual/asexual ED in plants have shown that the geographic ranges of asexuals extend beyond those of sexuals, often in areas of higher latitude or elevation. But very little is known about ED at fine scales, wherein coexistence of sexuals and asexuals may be permitted by differential niche occupation. Read More

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December 2018

Translation and application of equine genomics: The Havemeyer principles.

Authors:
E Bailey C Finno

Equine Vet J 2018 Dec 13. Epub 2018 Dec 13.

Department of Population Health and Reproduction, University of California, Davis, Davis, California, USA.

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December 2018

Data-driven adult asthma phenotypes based on clinical characteristics are associated with asthma outcomes twenty years later.

Allergy 2018 Dec 13. Epub 2018 Dec 13.

Inserm, Univ. Grenoble Alpes, CNRS, IAB, Team of environmental epidemiology applied to reproduction and respiratory health, 38000, Grenoble, France.

Background: Research based on cluster analyses led to the identification of particular phenotypes confirming phenotypic heterogeneity of asthma. The long-term clinical course of asthma phenotypes defined by clustering analysis remains unknown, although it is a key aspect to underpin their clinical relevance. We aimed to estimate risk of poor asthma events between asthma clusters identified 20 years earlier. Read More

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December 2018

Clinical implementation of gene panel testing for lysosomal storage diseases.

Mol Genet Genomic Med 2018 Dec 11. Epub 2018 Dec 11.

Paediatric Neurology Unit, Department of Paediatrics, UZ Brussel, Brussels, Belgium.

Background: The diagnostic workup in patients with a clinical suspicion of lysosomal storage diseases (LSD) is often difficult due to the variability in the clinical phenotype. The gold standard for diagnosis of LSDs consists of enzymatic testing. However, due to the sequential nature of this methodology and inconsistent genotype-phenotype correlations of certain LSDs, finding a diagnosis can be challenging. Read More

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December 2018

1α, 25-Dihydroxyvitamin D3 alters ectonucleotidase expression and activity in human cutaneous melanoma cells.

J Cell Biochem 2018 Dec 11. Epub 2018 Dec 11.

Department of Biochemistry and Molecular Biology, PPGBtox, CCNE, Federal University of Santa Maria, Santa Maria, RS, Brazil.

Purpose: We hypothesized that vitamin D decreases rates of adenosine formation in human cutaneous melanoma cells through the inhibition of extracellular adenosine 5'-triphosphate breakdown, thereby affecting tumor cell viability. Therefore, the objective of this study was to explore the mechanisms of action of 1α, 25-dihydroxyvitamin D3 (1,25(OH) D3) on the activity and expression of ectonucleotidases in cutaneous melanoma cells.

Methods: A human melanoma cell line, SK-Mel-28, was treated with 1 to 50 nM of the active vitamin D metabolite (1,25(OH) D3) over 24 hours, followed by determination of NTPDase1/CD39 and ecto-5'-nucleotidase/CD73 activity and expression rates of the purinergic system-related NTPDASE1, NT5E and adenosine deaminase and vitamin D receptor. Read More

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December 2018

Polychlorinated biphenyl (PCB) tissue-concentration thresholds for survival, growth, and reproduction in fish.

Environ Toxicol Chem 2018 Dec 11. Epub 2018 Dec 11.

US Geological Survey, Department of Interior Columbia Environmental Research Center, 4200 New Haven Rd., Columbia, MO 65201.

Polychlorinated biphenyls (PCBs) have left a legacy of environmental contamination, despite being banned from production and active use in the 1970's. PCBs persist in the environment and still have the potential to impact aquatic life. Our objective was to identify data from controlled laboratory studies of PCB-related adverse effects in fish and conduct a meta-analysis on mortality, growth, and reproductive (MGR) threshold responses. Read More

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December 2018

Realization of a 101  W single-frequency continuous wave all-solid-state 1064  nm laser by means of mode self-reproduction.

Opt Lett 2018 Dec;43(24):6017-6020

We realized a 101 W single-frequency continuous wave (CW) all-solid-state 1064 nm laser by means of mode self-reproduction in this Letter. Two identical laser crystals were placed into a resonator to relax the thermal lens of the laser crystals, and an imaging system was employed to realize cavity mode self-reproduced at the places of the laser crystals. Single-frequency operation of the resonator was realized by employing a new kind of high extinction ratio optical diode based on the terbium scandium aluminum garnet crystal to realize a stable unidirectional operation of the laser, together with introducing a large enough nonlinear loss to the resonator to effectively suppress the multi-mode oscillation and mode hopping of the laser. Read More

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December 2018

Cytokines and male infertility.

Eur Cytokine Netw 2018 Sep;29(3):73-82

Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Greece. "Papageorgiou General Hospital", Ring Road-Nea Efkarpia, 56403 Thessaloniki, Greece.

Many male infertility cases have no apparent cause, being characterized as idiopathic. Both inflammation and obesity have long been associated with infertility. On one hand, inflammation, such as orchitis and male accessory gland infections (MAGIs), are regulated by inflammatory cytokines. Read More

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September 2018
2 Reads

Comparative toxicogenomics of three insensitive munitions constituents 2,4-dinitroanisole, nitroguanidine and nitrotriazolone in the soil nematode Caenorhabditis elegans.

BMC Syst Biol 2018 Dec 14;12(Suppl 7):92. Epub 2018 Dec 14.

Environmental Laboratory, U.S. Army Engineer Research and Development Center, 3909 Halls Ferry Road, Vicksburg, MS, 39180, USA.

Background: Ecotoxicological studies on the insensitive munitions formulation IMX-101 and its components 2,4-dinitroanisole (DNAN), nitroguanidine (NQ) and nitrotriazolone (NTO) in various organisms showed that DNAN was the main contributor to the overall toxicity of IMX-101 and suggested that the three compounds acted independently. These results motivated this toxicogenomics study to discern toxicological mechanisms for these compounds at the molecular level.

Methods: Here we used the soil nematode Caenorhabditis elegans, a well-characterized genomics model, as the test organism and a species-specific, transcriptome-wide 44 K-oligo probe microarray for gene expression analysis. Read More

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December 2018

Dietary nutrient allocation to somatic tissue synthesis in emerging subimago freshwater mayfly Ephemera danica.

BMC Ecol 2018 Dec 14;18(1):57. Epub 2018 Dec 14.

Limnological Institute, University of Konstanz, Mainaustrasse 252, 78464, Constance, Germany.

Background: The relative importance of nutrients derived from different sources for tissue synthesis is crucial for predicting a species responds to changes in food availability. The ecological and physiological strategies that govern the incorporation and routing of nutrients for reproduction are often well understood. However, the role and adaptive value of both species and individual variation during early life-stage remain elusive. Read More

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December 2018

Epigenetic modifications acetylation and deacetylation play important roles in juvenile hormone action.

BMC Genomics 2018 Dec 14;19(1):934. Epub 2018 Dec 14.

Department of Entomology, College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY, 40546, USA.

Background: Epigenetic modifications including DNA methylation and post-translational modifications of histones are known to regulate gene expression. Antagonistic activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs) mediate transcriptional reprogramming during insect development as shown in Drosophila melanogaster and other insects. Juvenile hormones (JH) play vital roles in the regulation of growth, development, metamorphosis, reproduction and other physiological processes. Read More

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December 2018

Daphnia galeata responds to the exposure to an ichthyosporean gut parasite by down-regulation of immunity and lipid metabolism.

BMC Genomics 2018 Dec 14;19(1):932. Epub 2018 Dec 14.

Leibniz Institute of Freshwater Ecology and Inland Fisheries (IGB), Berlin, Germany.

Background: Regulatory circuits of infection in the emerging experimental model system, water flea Daphnia and their microparasites, remain largely unknown. Here we provide the first molecular insights into the response of Daphnia galeata to its highly virulent and common parasite Caullerya mesnili, an ichthyosporean that infects the gut epithelium. We generated a transcriptomic dataset using RNAseq from parasite-exposed (vs. Read More

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December 2018

Reproduction of the Charge Density Wave Phase Diagram in 1T-TiSe_{2} Exposes its Excitonic Character.

Phys Rev Lett 2018 Nov;121(22):226602

Centre for Advanced 2D Materials and Graphene Research Centre, National University of Singapore, Singapore 117546.

Recent experiments suggest that excitonic degrees of freedom play an important role in precipitating the charge density wave (CDW) transition in 1T-TiSe_{2}. Through systematic calculations of the electronic and phonon spectrum based on density functional perturbation theory, we show that the predicted critical doping of the CDW phase overshoots the experimental value by 1 order of magnitude. In contrast, an independent self-consistent many-body calculation of the excitonic order parameter and renormalized band structure is able to capture the experimental phase diagram in extremely good qualitative and quantitative agreement. Read More

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November 2018

Variations in seminal parameters over a 12-month period in captive bonnet monkeys.

Primates 2000 Oct;41(4):393-405

Institute for Research in Reproduction (ICMR), Jehangir Merwanji Street, Parel, 400012, Mumbai, India.

Semen samples were collected from adult fertile bonnet monkeys twice a month by penile electroejaculation for twelve consecutive months. Various parameters like semen volume, weight of ejaculate and coagulum, sperm count, sperm motility, sperm morphology, and functional parameters e.g. Read More

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October 2000

Monitoring hormones in urine and feces of captive bonobos (Pan paniscus).

Primates 2000 Jul;41(3):311-319

Center for Reproduction of Endangered Species, Zoological Society of San Diego, P. O. Box 120551, 92122, San Diego, California, USA.

Urinary and fecal hormones were analyzed on average every other day in 17 female bonobos kept at four US zoos (San Diego Zoo and Wild Animal Park, Milwaukee, Columbus, and Cincinnati). Ovarian cycle activity was monitored throughout the 15-month study period using estrogen and progesterone profiles and swelling charts. Behavioral data on sexual activity were also collected on a daily basis. Read More

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Advanced applications of nanotechnology in veterinary medicine.

Environ Sci Pollut Res Int 2018 Dec 13. Epub 2018 Dec 13.

Faculty of Veterinary Medicine, Department of Medicine and Infectious Diseases, Cairo University, Giza, Egypt.

The invention of new techniques to manipulate materials at their nanoscale had an evolutionary effect on various medical sciences. At the time, there are thousands of nanomaterials which can be divided according to their shape, origin, or their application. The nanotechnology provided new solutions for old problems. Read More

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December 2018
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Experimental exposure to gasohol impairs sperm quality with recognition of the classification pattern of exposure groups by machine learning algorithms.

Environ Sci Pollut Res Int 2018 Dec 13. Epub 2018 Dec 13.

Graduate Program in Environment and Regional Development, University of Western São Paulo - UNOESTE, Presidente Prudente, SP, 19067-175, Brazil.

Contamination caused by leakage at gas stations leads to possible exposure of the general population when in contact with contaminated water and soil. The present study aimed to evaluate the reproductive effects of exposure of adult male rats to gasohol and evaluate the performance of machine learning (ML) algorithms for pattern recognition and classification of the exposure groups. Rats were orally exposed to 0 (control), 16 (EA), 160 (EB), or 800 mg kg bw day of gasohol (EC), for 30 consecutive days. Read More

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December 2018

The impacts of laser zona thinning on hatching and implantation of vitrified-warmed mouse embryos.

Lasers Med Sci 2018 Dec 13. Epub 2018 Dec 13.

National Engineering Laboratory for Animal Breeding and Key Laboratory of Animal Genetics, Breeding and Reproduction, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology, China Agricultural University, Beijing, China.

Embryo vitrification has advantages in assisted reproduction yet it also induces zona hardening. Laser zona thinning (LZT) is considered as a solution yet its efficacy and security have not been well studied. In this study, we used vitrified-warmed morulae from 2-month-old and 10-month-old ICR female mice as model to investigate the impacts that LZT treatment brings to the in vitro hatching process and implantation by analyzing hatching rate, implantation rate, and blastocyst quality. Read More

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December 2018
1 Read

Effect of PM2.5 on invasion and proliferation of HeLa cells and the expression of inflammatory cytokines IL-1 and IL-6.

Oncol Lett 2018 Dec 27;16(6):7068-7073. Epub 2018 Sep 27.

Department of Gynecology, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510150, P.R. China.

Effects of different levels of PM2.5 on invasion and proliferation of HeLa cells and the expression levels of inflammatory cytokines IL-1 and IL-6 under 10 g/ml PM2.5 were investigated. Read More

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December 2018

Heritability and genetic architecture of reproduction-related traits in a temperate oak species.

2019 Feb 7;15(1). Epub 2018 Dec 7.

UMR BIOGECO 1202-INRA, University of Bordeaux, 33615, Pessac, France.

Reproduction, one of the main components of plant fitness, is highly variable in response to environmental cues, but little is known about the genetic determinism underlying reproduction-related traits in forest tree species. There is therefore an urgent need to characterize the genetic architecture of those traits if we are to predict the evolutionary trajectories of forest populations facing rapidly changing environment and mitigate their impacts. Using a full-sib family of pedunculate oak (), we investigated the within population variability of seed production and mean seed mass during four consecutive years. Read More

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February 2019

Asclepias Syriaca (Common Milkweed) flowering date shift in response to climate change.

Authors:
Aaron F Howard

Sci Rep 2018 Dec 13;8(1):17802. Epub 2018 Dec 13.

Biology Department, Franklin & Marshall College, Lancaster, 17604, USA.

The consequences of altered flowering dates due to climate change can be severe, especially for plants that rely on coordinated flower and pollinator emergence for reproduction. The plant Asclepias syriaca (Common Milkweed) relies on pollinators for movement of its pollen and evidence suggests that it has recently been declining. Given these factors and this plant's importance as a host species for the declining Danaus plexippus (Monarch Butterfly), it is critical to determine if its flowering is being modified by climate change. Read More

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December 2018

New Insight into Sperm Capacitation: A Novel Mechanism of 17β-Estradiol Signalling.

Int J Mol Sci 2018 Dec 12;19(12). Epub 2018 Dec 12.

Laboratory of Reproductive Biology, Institute of Biotechnology CAS, v.v.i., BIOCEV, Prumyslova 595, 252 50 Vestec, Czech Republic.

17β-estradiol (estradiol) is a natural estrogen regulating reproduction including sperm and egg development, sperm maturation-called capacitation-and sperm⁻egg communication. High doses can increase germ cell apoptosis and decrease sperm count. Our aim was to answer the biological relevance of estradiol in sperm capacitation and its effect on motility and acrosome reaction to quantify its interaction with estrogen receptors and propose a model of estradiol action during capacitation using kinetic analysis. Read More

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December 2018

Cyanobacterial Neurotoxin Beta-Methyl-Amino-l-Alanine Affects Dopaminergic Neurons in Optic Ganglia and Brain of .

Toxins (Basel) 2018 Dec 8;10(12). Epub 2018 Dec 8.

Department of Zoology, Functional Morphology, Stockholm University, Svante Arrhenius väg 18B, S-10691 Stockholm, Sweden.

The non-proteinogenic amino acid beta-methyl-amino-l-alanine (BMAA) is a neurotoxin produced by cyanobacteria. BMAA accumulation in the brain of animals via biomagnification along the food web can contribute to the development of neurodegenerative diseases such as Amyotrophic lateral sclerosis/Parkinsonism dementia complex (ALS/PDC), the latter being associated with a loss of dopaminergic neurons. is an important microcrustacean zooplankton species that plays a key role in aquatic food webs, and BMAA-producing cyanobacteria often form part of their diet. Read More

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December 2018

Cardiometabolic Health in Relation to Lifestyle and Body Weight Changes 3⁻8 Years Earlier.

Nutrients 2018 Dec 10;10(12). Epub 2018 Dec 10.

Department of Clinical Epidemiology, Biostatistics and Bioinformatics, University of Amsterdam, Amsterdam UMC, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.

The degree to which individuals change their lifestyle in response to interventions differs and this variation could affect cardiometabolic health. We examined if changes in dietary intake, physical activity and weight of obese infertile women during the first six months of the LIFEstyle trial were associated with cardiometabolic health 3⁻8 years later ( = 50⁻78). Lifestyle was assessed using questionnaires and weight was measured at baseline, 3 and 6 months after randomization. Read More

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December 2018

Analysis of the Transcriptome of the Red Seaweed with Emphasis on Reproductive Potential.

Mar Drugs 2018 Dec 7;16(12). Epub 2018 Dec 7.

Departamento de Biología, Facultad de Ciencias del Mar, Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, E-35017 Las Palmas, Spain.

is an intertidal marine seaweed and candidate model organism for both industry and academic research, owing to its ability to produce raw materials such as carrageenan. Here we report on the transcriptome of with the aim of providing new insights into the metabolic pathways and other functional pathways related to the reproduction of species. Next-generation sequencing was carried out with subsequent de novo assembly and annotation using state-of-the-art bioinformatic protocols. Read More

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December 2018

Quantitative and qualitative analysis of antimicrobial usage patterns in 180 selected farrow-to-finish pig farms from nine European countries based on single batch and purchase data.

J Antimicrob Chemother 2018 Dec 13. Epub 2018 Dec 13.

Veterinary Epidemiology Unit, Department of Reproduction, Obstetrics and Herd Health, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.

Objectives: Farm-level quantification of antimicrobial usage (AMU) in pig farms.

Methods: In a cross-sectional study, AMU data on group treatments administered to a single batch of fattening pigs from birth to slaughter (group treatment data) and antimicrobials purchased during 1 year (purchase data) were collected at 180 pig farms in nine European countries. AMU was quantified using treatment incidence (TI) based on defined (DDDvet) and used (UDDvet) daily doses and defined (DCDvet) and used (UCDvet) course doses. Read More

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December 2018

Re-assembly, quality evaluation, and annotation of 678 microbial eukaryotic reference transcriptomes.

Gigascience 2018 Dec 13. Epub 2018 Dec 13.

Department of Population Health & Reproduction, School of Veterinary Medicine, University of California Davis.

Background: De novo transcriptome assemblies are required prior to analyzing RNAseq data from a species without an existing reference genome or transcriptome. Despite the prevalence of transcriptomic studies, the effects of using different workflows, or "pipelines", on the resulting assemblies are poorly understood. Here, a pipeline was programmatically automated and used to assemble and annotate raw transcriptomic short read data collected by the Marine Microbial Eukaryotic Transcriptome Sequencing Project (MMETSP). Read More

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December 2018

The impact of a comprehensive electronic patient portal on the health service use: an interrupted time-series analysis.

Eur J Public Health 2018 Dec 12. Epub 2018 Dec 12.

Department of Psychiatry, IIS-Jimenez Diaz Foundation, Madrid, Spain.

Background: There is little empirical research on the potential benefit that electronic patient portals (EPP) can have on the care quality and health outcomes of diverse multi-ethnic international populations. The purpose of this study is to determine the extent to which an EPP was associated with improvements in health service use.

Methods: Using a quasi-experimental interrupted time-series approach, we assessed health service use before (April 2012-September 2015) and after (October 2015-December 2016) the implementation of a comprehensive EPP at four hospitals in Madrid, Spain. Read More

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December 2018
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Keeping it light: (Re)analyzing community-wide datasets without major infrastructure.

Gigascience 2018 Dec 13. Epub 2018 Dec 13.

Population Health and Reproduction, University of California, Davis, CA, USA.

DNA sequencing technology has revolutionized the field of biology, shifting biology from a data-limited to data-rich state. Central to the interpretation of sequencing data are the computational tools and approaches that convert raw data into biologically meaningful information. Both the tools and the generation of data are actively evolving, yet the practice of re-analysis of previously generated data with new tools is not commonplace. Read More

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December 2018

Feminization, altered gonadal development, and liver damage in least killifish (Heterandria formosa) exposed to sublethal concentrations of 17α-ethinylestradiol.

Ecotoxicol Environ Saf 2018 Dec 10;170:331-337. Epub 2018 Dec 10.

Department of Biology, University of Louisiana at Lafayette, Box 43602, Lafayette, LA 70504, USA.

The widespread use of the synthetic estrogen 17 α-ethinylestradiol (EE) has resulted in elevated levels in aquatic environments, where it is known to act as an endocrine disrupting chemical affecting fish and other aquatic organisms. Examining changes in the structure of the fish' gonads and liver has proven to be an effective approach for assessing these impacts. While changes have been reported for various fish species, it is not clear whether impacts are equally severe in live-bearing fishes. Read More

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December 2018

A Microbiota-Derived Bacteriocin Targets the Host to Confer Diarrhea Resistance in Early-Weaned Piglets.

Cell Host Microbe 2018 Dec;24(6):817-832.e8

State Key Laboratory of Agricultural Microbiology, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China; The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, Hubei 430070, China; Hubei Provincial Engineering Laboratory for Pig Precision Feeding and Feed Safety Technology, Wuhan, Hubei 430070, China. Electronic address:

Alternatives to antibiotics for preventing diarrhea in early-weaned farm animals are sorely needed. CM piglets (a native Chinese breed) are more resistant to early-weaning stress-induced diarrhea than the commercial crossbred LY piglets. Transferring fecal microbiota, but not saline, from healthy CM into LY piglets by oral administration prior to early weaning conferred diarrhea resistance. Read More

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December 2018

Meiotic drive of female-inherited supernumerary chromosomes in a pathogenic fungus.

Elife 2018 Dec 13;7. Epub 2018 Dec 13.

Environmental Genomics, Christian-Albrechts University of Kiel, Ploen, Germany.

Meiosis is a key cellular process of sexual reproduction involving the pairing of homologous sequences. In many species however, meiosis can also involve the segregation of supernumerary chromosomes, which can lack a homolog. How these unpaired chromosomes undergo meiosis is largely unknown. Read More

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December 2018
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