22,196 results match your criteria Renal Failure Chronic and Dialysis Complications


Clinical Implications of Sarcopenia in Patients Undergoing Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertention.

J Heart Lung Transplant 2020 Apr 30;39(4S):S33-S34. Epub 2020 Mar 30.

Respirology, Lung Transplant Program, Toronto General Research Institute, University Health Network, Toronto, ON, Canada.

Purpose: Pulmonary endarterectomy (PEA) is a curative surgical option for patients with chronic thromboembolic pulmonary hypertension (CTEPH), a disease resulting from chronic pulmonary thromboembolism. The role of sarcopenia (i.e. Read More

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http://dx.doi.org/10.1016/j.healun.2020.01.1185DOI Listing

Effects of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers on all-cause mortality, cardiovascular death, and cardiovascular events among peritoneal dialysis patients: A protocol for systematic review.

Medicine (Baltimore) 2020 Apr;99(17):e19767

Ottawa Hospital Research Institute, Ottawa Hospital.

Background: Based on the International Society for peritoneal dialysis (PD) recommendations, blockade of renin-angiotensin systems with an angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) improves residual kidney function in PD patients. However, the long-term effectiveness of ACEI/ARB use in PD patients has not been fully elucidated. We, therefore, intend to perform a systematic review and meta-analysis to summarize the effects of ACEI/ARB use on long-term mortality, cardiovascular outcomes, and adverse events among PD patients. Read More

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http://dx.doi.org/10.1097/MD.0000000000019767DOI Listing

COVID-19 and dialysis: why we should be worried.

J Nephrol 2020 06;33(3):401-403

Nephrology, Circolo Hospital-Macchi Foundation, Insubria University, Varèse, Italy.

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http://dx.doi.org/10.1007/s40620-020-00737-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175820PMC

[COVID-19, THE KIDNEY AND HYPERTENSION].

Harefuah 2020 Apr;159(4):231-234

Nephrology and Hypertension Institute, Samson Assuta University Hospital, Ashdod, Israel.

Introduction: COVID-19, is a new corona virus of the Beta Coronavirus genus which originated in bats. The virus first emerged in China in December 2019 and has rapidly spread since to other areas worldwide. The World Health Organization (WHO) has therefore recently declared it as the source of a pandemic. Read More

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Take proactive measures for the pandemic COVID-19 infection in the dialysis facilities.

J Formos Med Assoc 2020 05 11;119(5):895-897. Epub 2020 Apr 11.

Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Faculty of Renal Care, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jfma.2020.03.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151404PMC

An account of the first hours of the Covid-19 epidemic at the Nephrology Unit in Lodi (Lombardy).

G Ital Nefrol 2020 Apr 9;37(2). Epub 2020 Apr 9.

Struttura Complessa di Nefrologia e Dialisi, ASST di Lodi, Ospedale Maggiore di Lodi (LO).

Marco Farina and colleagues give us their account of the first days of the Covid-19 epidemic in the Nephrology Unit of the Ospedale Maggiore in Lodi. From the news trickling through from Codogno on the 20th of February to the hospitalization, the following day, of the first dialytic patient with signs of pneumonia, who later tested positive to the virus. They tell us of how the hospital has been completely restructured in the wake of the epidemic, at remarkable speed and providing an example for others to follow, and the great sense self-sacrifice displayed by all medical personnel. Read More

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[Managing patients in dialysis and with kidney transplant infected with Covid-19].

G Ital Nefrol 2020 Apr 9;37(2). Epub 2020 Apr 9.

Università degli Studi di Brescia, Dipartimento di Specialità Medico-Chirurgiche, Scienze Radiologiche e Sanità Pubblica, Brescia, Italia; ASST Spedali Civili di Brescia, Unità Operativa di Nefrologia, Brescia, Italia.

We are in the midst of a health emergency that is totally new for us all and that requires a concerted effort, especially when it comes to safeguarding patients on hemodialysis, and kidney transplant recipients. Brescia is currently a very active cluster of infections (2918 cases on the 17/03/2020), second only to Bergamo. The way our structure is organised has allowed us to treat nephropathic patients directly within the Nephrology Unit, following of course a great deal of reshuffling; at the moment, we are treating 21 transplanted patients and 17 on hemodialysis. Read More

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Renal graft survival in patients transplanted from organs of deceased donors

Rev Med Inst Mex Seguro Soc 2019 07 1;57(4):218-225. Epub 2019 Jul 1.

Instituto Mexicano del Seguro Social, Hospital de Especialidades “Dr. Bernardo Sepúlveda Gutiérrez”, Unidad de Trasplante Renal. Ciudad de México, México

Background: In Mexico, out of the total number of transplants it was reported, in 2014, a frequency of 29% of deceased donor renal transplantation (DDRT). The use of kidneys from deceased elderly donors is increasing over the years. Currently, some authors consider that six months after the transplant, patients who have been transplanted from deceased donors have a longer survival than those who are still undergoing dialysis replacement therapy. Read More

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Management of Coronary Disease in Patients with Advanced Kidney Disease.

N Engl J Med 2020 04 30;382(17):1608-1618. Epub 2020 Mar 30.

From the New York University Grossman School of Medicine (S. Bangalore, H.R.R., J.S.B., J.D.N., J.S.H.), Mount Sinai Hospital (G.W.S.), the Cardiovascular Research Foundation (G.W.S., Z.A.A.), and Columbia University Irving Medical Center/New York Presbyterian Hospital (Z.A.A.), New York, Albany Medical College and Albany Medical Center, Albany (M.S.S.), and St. Francis Hospital, Roslyn (Z.A.A.) - all in New York; the Department of Medicine, Stanford University School of Medicine, Stanford, CA (D.J.M., G.M.C.); Duke Clinical Research Institute, Durham, NC (S.M.O., S. Broderick, Z.H., D.B.M., K.P.A.); the National, Heart, Lung and Blood Institute, Bethesda, MD (J.L.F.); E.N. Meshalkin National Medical Research Center, Novosibirsk (E.I.K.), and Bakulev National Medical Research Center for Cardiovascular Surgery, Moscow (O.B.) - both in Russia; Mediterranea Cardiocentro, Naples, Italy (C.B.); Batra Hospital and Medical Research Centre, New Delhi, India (U.K.); Medical University of Warsaw (T.M.) and the Department of Coronary and Structural Heart Diseases, Institute of Cardiology (R.P.) - both in Warsaw, Poland; Columbia Veterans Affairs (VA) Health Care System, Columbia, SC (R.O.M.); Hennepin Healthcare, University of Minnesota, Minneapolis (C.A.H.); VA New England Healthcare System and Boston University School of Medicine, Boston (W.E.B.); and Saint Luke's Mid America Heart Institute/University of Missouri-Kansas City (J.A.S.) and St. Louis University School of Medicine Center for Comprehensive Cardiovascular Care, St. Louis (B.R.C.).

Background: Clinical trials that have assessed the effect of revascularization in patients with stable coronary disease have routinely excluded those with advanced chronic kidney disease.

Methods: We randomly assigned 777 patients with advanced kidney disease and moderate or severe ischemia on stress testing to be treated with an initial invasive strategy consisting of coronary angiography and revascularization (if appropriate) added to medical therapy or an initial conservative strategy consisting of medical therapy alone and angiography reserved for those in whom medical therapy had failed. The primary outcome was a composite of death or nonfatal myocardial infarction. Read More

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http://dx.doi.org/10.1056/NEJMoa1915925DOI Listing

A Case of Novel Coronavirus Disease 19 in a Chronic Hemodialysis Patient Presenting with Gastroenteritis and Developing Severe Pulmonary Disease.

Am J Nephrol 2020 28;51(5):337-342. Epub 2020 Mar 28.

Department of Medicine, Division of Nephrology, Hypertension and Kidney Transplantation, University of California Irvine Medical Center, Orange, California, USA,

Novel coronavirus disease 2019 (COVID-19) is a highly infectious, rapidly spreading viral disease with an alarming case fatality rate up to 5%. The risk factors for severe presentations are concentrated in patients with chronic kidney disease, particularly patients with end-stage renal disease (ESRD) who are dialysis dependent. We report the first US case of a 56-year-old nondiabetic male with ESRD secondary to IgA nephropathy undergoing thrice-weekly maintenance hemodialysis for 3 years, who developed COVID-19 infection. Read More

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http://dx.doi.org/10.1159/000507417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179539PMC
May 2020
2.669 Impact Factor

COVID-19 Infection in a Patient with End-Stage Kidney Disease.

Nephron 2020 27;144(5):245-247. Epub 2020 Mar 27.

Division of Nephrology, Changzheng Hospital, Second Military Medical University, Shanghai, China,

Since December 2019, the epidemic of coronavirus disease 2019 (COVID-19) has spread very rapidly in China and worldwide. In this article, we report on a 75-year-old man infected with 2019 novel coronavirus who has end-stage kidney disease (ESKD). COVID-19 patients with ESKD need isolation dialysis, but most of them cannot be handled in time due to limited continuous renal replacement therapy (CRRT) machines. Read More

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http://dx.doi.org/10.1159/000507261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179522PMC

Two cases of severe Purtscher-like retinopathy demonstrating recurrence and progression to neovascularization and vitreous hemorrhage.

Am J Ophthalmol Case Rep 2020 Jun 12;18:100664. Epub 2020 Mar 12.

Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.

Purpose: To report the clinical course of two cases with Purtscher-like retinopathy (PLR), associated with peritoneal dialysis (PD), demonstrating disease recurrence and progression to neovascularization and vitreous hemorrhage.

Observations: Case 1 (45-year old woman) experienced acute bilateral vision loss. Medical history included hypertension, end-stage renal failure (ESRF), PD, and obstructive sleep apnea. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082518PMC

Comparison of the effect of linear and step-wise sodium and ultrafiltration profiling on dialysis adequacy in patients undergoing hemodialysis.

Saudi J Kidney Dis Transpl 2020 Jan-Feb;31(1):44-52

Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Patients with chronic renal failure undergoing hemodialysis (HD) need to receive adequate dialysis. Dialysis inadequacy leads to an increase in the side effects and even frequent hospitalizations as well as increased therapeutic costs. Considering the fact that improving the adequacy of dialysis is one of the goals of nursing care in these patients, this study aimed to compare the effect of linear and step-wise sodium-ultrafiltration (UF) profiling on HD adequacy. Read More

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http://dx.doi.org/10.4103/1319-2442.279960DOI Listing

Congress Report from Highly Scientific Nephrology Congresses in the Balkans, 15th Bantao and 6th MSNDTAO Congress.

Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2019 Dec;40(3):117-122

University Department of Nephrology, Medical Faculty, University of Skopje, North Macedonia.

In the period from 26th until 29th of September 2019, the 15th BANTAO Congress (Balkan Cities Association of Nephrology, Dialysis, Transplantation and Artificial Organs) in conjunction with the 6th Congress of the Macedonian Society of Nephrology, Dialysis, Transplantation and Artificial Organs (MSNDTAO) was held in Skopje, Republic of North Macedonia, hosted by the Macedonian Academy of Sciences and Arts (MASA). MSNDTAO was created in 1992 and the First Congress of the MSNDTAO was held on 9th October 1993 in Ohrid when, also, the Balkan Association of Nephrology, Dialysis, Transplantation and Artificial Organs (BANTAO) was established, as the only professional association of this kind in the Balkans and Southern Europe. Since then, MSNDTAO has been very active in education and collaboration with BANTAO, the European Renal Association (ERA-EDTA) and the International Society of Nephrology (ISN). Read More

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http://dx.doi.org/10.2478/prilozi-2020-0011DOI Listing
December 2019

Assessment and management of volume overload among patients on chronic dialysis.

Curr Vasc Pharmacol 2020 Feb 24. Epub 2020 Feb 24.

Nephrology Department, "Grigore T. Popa" University of Medicine and Pharmacy Iasi. Romania.

Volume overload is the most common complication in end-stage renal disease (ESRD) patients, being directly related to numerous complications including resistant hypertension, cardiac hypertrophy, congestive heart failure or arterial stiffness, among others. Therefore, volume overload is now considered an important risk factor for hard outcomes, like all-cause or cardiovascular mortality. Relying solely on clinical examination for assessing volume overload in ESRD patients lacks sensitivity and specificity. Read More

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http://dx.doi.org/10.2174/1570161118666200225093827DOI Listing
February 2020

The Perfect Storm: Stakeholder Perspectives on Factors Contributing to Hospital Admissions for Patients Undergoing Maintenance Hemodialysis.

Nephrol Nurs J 2020 Jan-Feb;47(1):11-20

Research Associate Professor and the NewCourtland Term Chair in Health Transitions Research, the University of Pennsylvania School of Nursing, Philadelphia, PA.

Patients living with end stage renal disease (ESRD) who are undergoing hemodialysis experience frequent hospitalizations associated with complications of care and exacerbations of illness. Efforts to reduce hospitalizations have had limited success. The purpose of this study was to explore why hospitalizations occur from the perspectives of patients undergoing hemodialysis treatment, their caregivers, and health care providers. Read More

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Contributing factors and short-term surgical outcomes of patients with early-onset rectal cancer.

Am J Surg 2020 04 16;219(4):578-582. Epub 2020 Feb 16.

Department of Surgery, University of Arizona Medical Center, United States. Electronic address:

Introduction: The aim of this study was to evaluate patient factors that contribute to increased incidence of early onset rectal cancer and analyze the short-term surgical outcomes of patients undergoing surgery.

Methods: A 2-year review (2015-2016) of the ACS-NSQIP included patients with rectal cancer who underwent surgical management. Patients were stratified into early-onset RC (<50-years) and late-onset RC (≥50-years). Read More

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http://dx.doi.org/10.1016/j.amjsurg.2020.02.028DOI Listing

Peritoneal dialysis in extremely and very low-birth-weight infants.

Perit Dial Int 2020 Mar 17;40(2):233-236. Epub 2020 Jan 17.

Faculty of Medicine and University Hospital Cologne, Department of Pediatrics, Pediatric Nephrology, University of Cologne, Germany.

The outcome of extremely low-birth-weight (ELBW) and very low-birth-weight (VLBW) infants has substantially improved in recent years. As acute kidney injury is frequent in these infants due to various risk factors, there is an increasing demand for renal replacement therapy in these patients. Data on that topic, however, are scarce. Read More

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http://dx.doi.org/10.1177/0896860819887292DOI Listing

[Prevalence of Pulmonary Hypertension in Dialysis Patients with End-stage Renal Disease].

Pneumologie 2020 Apr 13;74(4):210-216. Epub 2020 Feb 13.

Abteilung Pneumologie Klinikum Augustinum München, ehemals Ambulanz für pulmonale Hypertonie, Medizinische Klinik II des Universitätsklinikums Gießen.

Background:  In patients with end-stage renal disease (ESRD), pulmonary hypertension (PH) is a frequent complication with different etiologies and a 17 - 56 % prevalence rate. We evaluated the impact of fluid retention measured by bioimpedance on the prevalence of PH in this patient cohort.

Methods:  All patients with ESRD at the dialysis center of the Medical Clinic II of the University Hospital Gießen were invited to participate in the study and undergo non-invasive PH screening. Read More

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http://dx.doi.org/10.1055/a-1069-0691DOI Listing

Pulmonary hypertension in patients with end stage renal disease undergoing hemodialysis.

Niger J Clin Pract 2020 Feb;23(2):198-204

Department VII, Internal Medicine II, University of Medicine and Pharmacy Victor Babes; County Clinical Emergency Hospital Pius Brinzeu, Timisoara, Romania.

Background: Pulmonary hypertension (PH) is a serious cardiovascular complication in patients with end stage renal disease (ESRD) undergoing hemodialysis (HD) via arterio-venous fistulas (AVF).

Aim: The aim of this study was to assess pulmonary vascular resistance (PVR), AVF flow volume (AVF-FV) and cardiac output (CO) and to highlight the impact of their augmentation, as well as of the duration of HD, on the occurrence of PH in patients with ESRD.

Methods: Our study group consisted of 51 dialyzed patients, with ESRD, without history of PH. Read More

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http://dx.doi.org/10.4103/njcp.njcp_278_19DOI Listing
February 2020

Optimal cut-off value of high-sensitivity troponin I in diagnosing myocardial infarction in patients with end-stage renal disease.

Medicine (Baltimore) 2020 Jan;99(5):e18580

Department of Nephrology, Ajou University School of Medicine, Yeongtong-gu, Suwon, Gyeonggi-do, Republic of Korea.

End-stage renal disease (ESRD) is a major risk factor for cardiovascular disease and the prognosis after myocardial infarction (MI) is dismal. Although cardiac troponin is a key diagnostic test, troponin levels are often elevated in ESRD patients without evidence of MI. Thus, this study attempted to determine the optimal diagnostic value of high-sensitivity troponin I (hsTnI) by dialysis modality in ESRD patients. Read More

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http://dx.doi.org/10.1097/MD.0000000000018580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004770PMC
January 2020

The influence of atrial fibrillation on the mortality of incident ESRD patients undergoing maintenance hemodialysis.

PLoS One 2020 30;15(1):e0228405. Epub 2020 Jan 30.

Division of Nephrology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.

Background: Atrial fibrillation (AF) is highly prevalent, occurring in 1%-2% of the adult population, increasing the risk of stroke, and resulting in considerable healthcare costs. While stroke is a major complication of AF, end-stage renal disease (ESRD) patients also have a high risk of stroke, suggesting that AF is a possible risk factor for mortality of ESRD patients. However, whether the existence of AF at the initiation of hemodialysis predicts higher mortality risk of incident ESRD patients remains to be defined. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0228405PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992232PMC

Behavioral Changes During Development of Chronic Kidney Disease in Rats.

Front Med (Lausanne) 2019 9;6:311. Epub 2020 Jan 9.

Institute of Molecular Biomedicine, Faculty of Medicine, Comenius University in Bratislava, Bratislava, Slovakia.

Decreased renal function due to chronic kidney disease (CKD) is associated with anxiety and cognitive decline. Although these mental disorders are often obvious in late stage renal disease patients, they might be unnoticeable or are neglected in early stages of the CKD development. Associations between renal and cognitive dysfunction have been indicated by studies performed mainly in patients undergoing dialysis, which itself represents a stress and decreased quality of life. Read More

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http://dx.doi.org/10.3389/fmed.2019.00311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962109PMC
January 2020

Clinical outcomes of incident peritoneal dialysis patients coming from kidney transplantation program: A case-control study.

PLoS One 2020 24;15(1):e0227870. Epub 2020 Jan 24.

Department of Internal Medicine, Division of Nephrology, Federal University of São Paulo, São Paulo, Brazil.

Introduction: Brazil ranks second in the absolute number of transplantations in the world. Despite improvements in graft survival, many patients will progress to graft loss and return to dialysis. Concerns exist regarding adverse clinical outcomes in this population when undergone peritoneal dialysis (PD). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0227870PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980492PMC

Severe peripheral arterial diseases in hemodialysis patient: A case report.

Medicine (Baltimore) 2020 Jan;99(4):e18760

Department of Nephrology, University of South China affiliated Changsha Central Hospital.

Rationale: Peripheral arterial diseases (PADs) is defined as a systemic arterial disorders involving the lower extremity arteries, iliac, and carotid, which is developed more common in patients with chronic kidney disease (CKD) than individual with normal renal function. Concurrence of mesenteric artery disease and lower extremity artery disease (LEAD) is rare. The presence of PADs in patients receiving hemodialysis leads to a dramatic increase in risk of cardiovascular mortality. Read More

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http://dx.doi.org/10.1097/MD.0000000000018760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004584PMC
January 2020
5.723 Impact Factor

Patient-related risk factors for unplanned 30-day readmission following total knee arthroplasty: a narrative literature review.

ANZ J Surg 2020 Jan 22. Epub 2020 Jan 22.

Department of Surgery, St Vincent's Hospital, The University of Melbourne, Melbourne, Victoria, Australia.

Osteoarthritis is a debilitating condition as well as a growing global health problem, and total knee arthroplasty (TKA) is an effective treatment for advanced disease. Unplanned 30-day hospital readmission is an indicator of complications, which is a significant financial burden on healthcare systems. We reviewed the literature to better understand the patient-related factors associated with unplanned 30-day readmission following TKA. Read More

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http://dx.doi.org/10.1111/ans.15695DOI Listing
January 2020

Gender differences in clinical features and complications of infective endocarditis: 11-year experience of a single institute in Egypt.

Egypt Heart J 2020 Jan 21;72(1). Epub 2020 Jan 21.

Department of Cardiology, Kasr Al Aini Hospital, Faculty of Medicine, Cairo University, Cairo, 11562, Egypt.

Background: No data exists about the gender differences among patients with infective endocarditis (IE) in Egypt. The objective was to study possible gender differences in clinical profiles and outcomes of patients in the IE registry of a tertiary care center over 11 years.

Results: The IE registry included 398 patients with a median age of 30 years (interquartile range, 15 years); 61. Read More

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http://dx.doi.org/10.1186/s43044-020-0039-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974112PMC
January 2020

Peritoneal Dialysis.

Rev Assoc Med Bras (1992) 2020 Jan 13;66Suppl 1(Suppl 1):s37-s44. Epub 2020 Jan 13.

Hospital do Rim - Fundação Oswaldo Ramos, São Paulo, Brasil; Disciplina de Nefrologia, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil.

Peritoneal dialysis (PD) is a renal replacement therapy based on infusing a sterile solution into the peritoneal cavity through a catheter and provides for the removal of solutes and water using the peritoneal membrane as the exchange surface. This solution, which is in close contact with the capillaries in the peritoneum, allows diffusion solute transport and osmotic ultrafiltration water loss since it is hyperosmolar to plasma due to the addition of osmotic agents (most commonly glucose). Infusion and drainage of the solution into the peritoneal cavity can be performed in two ways: manually (continuous ambulatory PD), in which the patient usually goes through four solution changes throughout the day, or machine-assisted PD (automated PD), in which dialysis is performed with the aid of a cycling machine that allows changes to be made overnight while the patient is sleeping. Read More

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http://dx.doi.org/10.1590/1806-9282.66.S1.37DOI Listing
January 2020

Chronic Kidney Disease.

Rev Assoc Med Bras (1992) 2020 Jan 13;66Suppl 1(Suppl 1):s03-s09. Epub 2020 Jan 13.

Doutor em Nefrologia pela Universidade Federal de São Paulo, São Paulo, SP, Brasil.

Chronic kidney disease is highly prevalent (10-13% of the population), irreversible, progressive, and associated with higher cardiovascular risk. Patients with this pathology remain asymptomatic most of the time, presenting the complications typical of renal dysfunction only in more advanced stages. Its treatment can be conservative (patients without indication for dialysis, usually those with glomerular filtration rate above 15 ml/minute) or replacement therapy (hemodialysis, peritoneal dialysis, and kidney transplantation). Read More

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http://dx.doi.org/10.1590/1806-9282.66.S1.3DOI Listing
January 2020

Natural Vascular Remodelling After Arteriovenous Fistula Creation in Dialysis Patients With and Without Previous Ipsilateral Vascular Access.

Eur J Vasc Endovasc Surg 2020 02 3;59(2):277-287. Epub 2020 Jan 3.

Department of Vascular Surgery, Maastricht University Medical Centre+, Maastricht, the Netherlands.

Objective: The aim of the study was to observe the natural haemodynamic changes after arteriovenous fistula (AVF) creation in haemodialysis patients with and without a previous ipsilateral vascular access.

Methods: This was a retrospective, single centre cohort study. Patient demographics were registered and pre- and post-operative vessel ultrasound examinations were performed at regular follow up intervals. Read More

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http://dx.doi.org/10.1016/j.ejvs.2019.10.010DOI Listing
February 2020

A comparison of quality of life between patients treated with different dialysis modalities in Taiwan.

PLoS One 2020 6;15(1):e0227297. Epub 2020 Jan 6.

School of Nursing, National Defense Medical Center, Taipei City, Taiwan (R.O.C.).

Purpose: This study compared the quality of life (QOL) of hemodialysis (HD) and peritoneal dialysis (PD) patients in Taiwan.

Methods: This cross-sectional study recruited end-stage renal disease patients from 34 Taiwanese hospitals or clinics. Patient characteristics, diagnoses, and laboratory data were extracted from charts. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0227297PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944387PMC

Inflammation and Oxidative Stress in Chronic Kidney Disease-Potential Therapeutic Role of Minerals, Vitamins and Plant-Derived Metabolites.

Int J Mol Sci 2019 Dec 30;21(1). Epub 2019 Dec 30.

Department of Pharmacy, School of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, I-84084 Fisciano, SA, Italy.

Chronic kidney disease (CKD) is a debilitating pathology with various causal factors, culminating in end stage renal disease (ESRD) requiring dialysis or kidney transplantation. The progression of CKD is closely associated with systemic inflammation and oxidative stress, which are responsible for the manifestation of numerous complications such as malnutrition, atherosclerosis, coronary artery calcification, heart failure, anemia and mineral and bone disorders, as well as enhanced cardiovascular mortality. In addition to conventional therapy with anti-inflammatory and antioxidative agents, growing evidence has indicated that certain minerals, vitamins and plant-derived metabolites exhibit beneficial effects in these disturbances. Read More

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http://dx.doi.org/10.3390/ijms21010263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981831PMC
December 2019

Baseline and Outcome Characteristics of Multiple Valve Surgery Compared with Single Valve Procedures in Mainland China: A Multicenter Experience.

Heart Surg Forum 2019 12 17;22(6):E486-E493. Epub 2019 Dec 17.

Department of Cardiac Surgery, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.

Background: To compare baseline and outcome characteristics of multiple valve surgery with single-valve procedures in a multicenter patient population of mainland China.

Methods: From January 2008 to December 2012, data from 14,322 consecutive patients older than 16 years who underwent heart valve surgery at five cardiac surgical centers (except pulmonary valve operations) were collected. The patients were divided into seven subgroups according to the type of valve procedures, and baseline characteristics and postoperative outcomes were contrasted between all seven combinations of single-valve and multiple-valve procedures involving aortic, mitral, and tricuspid valves. Read More

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http://dx.doi.org/10.1532/hsf.2369DOI Listing
December 2019

Altered functional connectivity density in the brains of hemodialysis end-stage renal disease patients: An in vivo resting-state functional MRI study.

PLoS One 2019 31;14(12):e0227123. Epub 2019 Dec 31.

Department of Nephrology, The Ninth People's Hospital of Chongqing, Chongqing, China.

Background: End-stage renal disease (ESRD) patients usually suffer from a high prevalence of central nervous system abnormalities, including cognitive impairment and emotional disorders, which severely influence their quality of life. There have been many neuroimaging research developments in ESRD patients with brain function abnormalities; however, the dysfunction of the salience network (SN) of them has received little attention. The purpose of this study was to investigate the changes of global functional connectivity density (gFCD) in brains of ESRD patients undergoing hemodialysis using resting-state functional magnetic resonance imaging (re-fMRI). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0227123PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938298PMC

Comparison of Upper Limb Translocated Femoral Vein and Prosthetic Arteriovenous Bridge Grafts.

Cureus 2019 Nov 22;11(11):e6219. Epub 2019 Nov 22.

Surgery, Aga Khan University Hospital, Karachi, PAK.

Introduction Native veins are an ideal option for dialysis in a patient with chronic kidney disease (CKD) as compared to a prosthetic graft. Femoral vein (FV) translocation to the upper arm is also an alternative to a prosthetic graft as reported in the literature when all options of using the native veins of the arms are exhausted. Thus, we aimed to compare the patency of the upper limb translocated FV arteriovenous fistula (AVF) with a prosthetic arteriovenous bridge graft (AVBG). Read More

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http://dx.doi.org/10.7759/cureus.6219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929260PMC
November 2019

Experiences, perspectives and values of Indigenous peoples regarding kidney transplantation: systematic review and thematic synthesis of qualitative studies.

Int J Equity Health 2019 12 30;18(1):204. Epub 2019 Dec 30.

Research and Innovation Centre, Eastern Institute of Technology, Napier, 4112, New Zealand.

Background: Kidney transplantation is considered best practice treatment for end stage kidney disease (ESKD), however Indigenous patients are substantially less likely to receive either a deceased or live donor kidney transplant than non-Indigenous patients. We describe Indigenous peoples' experiences and perspectives including traditional values around kidney transplantation to inform international transplant programs.

Methods: We conducted a systematic review of qualitative studies involving Indigenous adults who have experience with or perceptions of kidney transplantation. Read More

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http://dx.doi.org/10.1186/s12939-019-1115-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937677PMC
December 2019

Impact of Subtotal Parathyroidectomy on Clinical Parameters and Quality of Life in Hemodialysis Patients with Secondary Hyperparathyroidism.

Endocrinol Metab (Seoul) 2019 12;34(4):367-373

Mansoura Nephrology and Dialysis Unit (MNDU), Mansoura Faculty of Medicine, Mansoura, Egypt.

Background: Impairment of quality of life (QOL) is a key clinical characteristic of patients with end-stage renal disease (ESRD), and can be especially severe in the presence of secondary hyperparathyroidism (SHPT). Despite the proven success of parathyroidectomy (PTX) in controlling biochemical parameters in patients with severe SHPT, evidence is lacking regarding the effects of PTX on various clinical outcomes, including QOL.

Methods: Twenty ESRD patients on maintenance hemodialysis with SHPT who underwent subtotal PTX were included in an observational longitudinal study. Read More

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http://dx.doi.org/10.3803/EnM.2019.34.4.367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935777PMC
December 2019

Risk factors and associated complications of acute kidney injury in adult patients undergoing a craniotomy.

Clin Neurol Neurosurg 2020 Mar 16;190:105642. Epub 2019 Dec 16.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA, United States; Center for Perioperative Research, Brigham and Women's Hospital, United States. Electronic address:

Objective: Understanding the risk factors and clinical outcomes associated with acute kidney injury (AKI) after craniotomy may help clinicians identify perioperative patients at risk for AKI and lead clinicians to institute preventive measures. The objective of this study was to identify risk factors associated with AKI after craniotomy and understand whether patients who develop AKI after craniotomy have worse clinical outcomes.

Patients And Methods: We performed a retrospective, propensity score matched cohort study consisting of 344 patients who developed an AKI or required renal dialysis post-operatively versus those who did not. Read More

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http://dx.doi.org/10.1016/j.clineuro.2019.105642DOI Listing

Comparison of Postoperative Complications and Survivorship of Total Hip and Knee Arthroplasty in Dialysis and Renal Transplantation Patients.

J Arthroplasty 2020 Apr 26;35(4):971-975. Epub 2019 Oct 26.

Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA.

Background: Chronic renal failure (CRF) is an established risk factor for surgical site infection (SSI) and periprosthetic joint infection (PJI) after primary total joint arthroplasty. However, there is limited literature comparing outcomes between patients who receive dialysis vs renal transplantation. We examined and compared clinical outcomes of patients receiving dialysis vs those who had a prior renal transplantation. Read More

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http://dx.doi.org/10.1016/j.arth.2019.10.038DOI Listing
April 2020
2.666 Impact Factor

Risk factors for restless legs syndrome in hemodialysis patients in Taiwan: A case-control study.

Medicine (Baltimore) 2019 Dec;98(51):e18450

Department of Public Health, College of Medicine.

Restless legs syndrome (RLS) increases the risks of cardiovascular disease and death in hemodialysis (HD) patients. Previous studies of risk factors for RLS in HD patients have yielded varying results. We attempted to identify risk factors for RLS in HD patients in Taiwan. Read More

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http://dx.doi.org/10.1097/MD.0000000000018450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940127PMC
December 2019

[Pregnancy during chronic hemodialysis. A series of cases].

Rev Med Chil 2019 Jun;147(6):709-717

Sección de Nefrología, Hospital Clínico Universidad de Chile, Santiago, Chile.

Background: Pregnancies in women with end stage renal failure are uncommon. However, correction of anemia and improvement in dialysis techniques increases the rate of successful pregnancies.

Aim: To describe a 16 years' experience treating pregnant women on hemodialysis and to analyze maternal-fetal outcomes. Read More

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http://dx.doi.org/10.4067/S0034-98872019000600709DOI Listing

Outcome preferences of older people with multiple chronic conditions and hypertension: a cross-sectional survey using best-worst scaling.

Health Qual Life Outcomes 2019 Dec 19;17(1):186. Epub 2019 Dec 19.

Division of Geriatrics and Gerontology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.

Background: Older people with hypertension and multiple chronic conditions (MCC) receive complex treatments and face challenging trade-offs. Patients' preferences for different health outcomes can impact multiple treatment decisions. Since evidence about outcome preferences is especially scarce among people with MCC our aim was to elicit preferences of people with MCC for outcomes related to hypertension, and to determine how these outcomes should be weighed when benefits and harms are assessed for patient-centered clinical practice guidelines and health economic assessments. Read More

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http://dx.doi.org/10.1186/s12955-019-1250-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924040PMC
December 2019

Hypoalbuminemia differently affects the serum bone turnover markers in hemodialysis patients.

Int J Med Sci 2019 21;16(12):1583-1592. Epub 2019 Oct 21.

Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.

Renal osteodystrophy (ROD) represents bone disorders related to chronic kidney disease (CKD) and several bone biomarkers are used clinically to predict ROD in CKD and hemodialysis (HD) patients. Serum albumin associates with inflammation other than nutritional status in these patients. Chronic inflammation is proved to relate with bone loss, however, the influence of hypoalbuminemia on bone biomarkers is still unclear. Read More

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http://dx.doi.org/10.7150/ijms.39158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909808PMC

Possible link between dental diseases and arteriosclerosis in patients on hemodialysis.

PLoS One 2019 13;14(12):e0225038. Epub 2019 Dec 13.

Department of Pediatric Dentistry, Division of Oral Infection and Disease Control, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan.

Background: Patients on hemodialysis must undergo this procedure at a hospital three times weekly and might be unable to visit a dentist. In addition, dentists might hesitate to provide oral care because such patients tend to bleed because they are medicated with anticoagulants, are susceptible to bacterial infections, and might have unusual drug reactions. We postulated that patients on hemodialysis have worse oral status than healthy people, which in turn might predispose such patients to systemic complications. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0225038PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910673PMC

Dataset supporting blood pressure prediction for the management of chronic hemodialysis.

Sci Data 2019 12 9;6(1):313. Epub 2019 Dec 9.

Division of Nephrology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan.

Hemodialysis (HD) is a treatment given to patients with renal failure. Notable treatment-related complications include hypotension, cramps, insufficient blood flow, and arrhythmia. Most complications are associated with unstable blood pressure during HD. Read More

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http://dx.doi.org/10.1038/s41597-019-0319-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901464PMC
December 2019

Acute oxalate nephropathy associated with infection.

BMJ Case Rep 2019 Dec 5;12(12). Epub 2019 Dec 5.

Department of Nephrology, Saint Vincent Hospital, Worcester, Massachusetts, USA.

Acute oxalate nephropathy has been associated with chronic diarrheal illness and only one case has been reported due to acute diarrhea secondary to colitis. To the best of our knowledge, this is the second case report of acute oxalate nephropathy due to colitis. A 75-year-old man with a medical history of hypertension, type 2 diabetes mellitus, chronic kidney disease stage IV, recent colitis was admitted for acute kidney injury with a creatinine (Cr) of 8. Read More

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http://dx.doi.org/10.1136/bcr-2019-231099DOI Listing
December 2019

Penile gangrene due to calciphylaxis: a multidisciplinary approach to a complex clinical challenge.

BMJ Case Rep 2019 Dec 5;12(12). Epub 2019 Dec 5.

Plastic and Reconstructive Surgery, Flinders Medical Centre, Bedford Park, South Australia, Australia.

Penile calciphylaxis is a rare but clinically challenging condition to manage. While multiple treatment options have been proposed, the underlying evidence is anecdotal, and the overall prognosis remains extremely poor. We describe the case of a patient who underwent urgent debridement of a suspected gangrenous penile tip, who was intraoperatively found to have penile calciphylaxis. Read More

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http://dx.doi.org/10.1136/bcr-2019-232138DOI Listing
December 2019

Secondary hyperparathyroidism: recurrence after total parathyroidectomy with autotransplantation.

Swiss Med Wkly 2019 12 4;149:w20160. Epub 2019 Dec 4.

Department of General and Visceral Surgery, University Hospital Basel, Switzerland.

Background: Secondary hyperparathyroidism (sHPTH) is common in patients with end-stage chronic kidney disease. If drug therapy fails, total parathyroidectomy with autotransplantation of parathyroid tissue into the forearm (PTX-AT) is the most widely used procedure. High recurrence rates of sHPTH following PTX-AT are reported in the literature. Read More

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http://dx.doi.org/10.4414/smw.2019.20160DOI Listing
December 2019

Newer Oral Anticoagulant in Chronic Kidney Disease: What we Should Know.

J Assoc Physicians India 2019 Nov;67(11):60-65

Consultant Medicine and Nephrologist, Command Hospital Airforce, Bangalore, Karnataka.

Oral anticoagulants are commonly prescribed in patients with kidney diseases having atrial fibrillation and thromboembolic risk. It is very important to understand their clinical pharmacology and changes that may occur as GFR declines. Risks and benefits of newer oral anticoagulants are different in patients with CKD and patients with ESRD. Read More

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November 2019

Midterm outcome of renal function after branched thoracoabdominal aortic aneurysm repair.

J Vasc Surg 2020 Apr 29;71(4):1119-1127. Epub 2019 Nov 29.

Department of Vascular and Endovascular Surgery, University Hospital of Regensburg, Regensburg, Germany; Department of Vascular Surgery, University Hospital Zürich, Zürich, Switzerland. Electronic address:

Objective: The aim of this study was to investigate the incidence and impact of acute and chronic kidney dysfunction after branched endovascular aortic aneurysm repair (BEVAR) perioperatively and during follow-up.

Methods: Patients with a thoracoabdominal aortic aneurysm were treated with BEVAR. Serum creatinine; estimated glomerular filtration rate at baseline, after 48 hours, at discharge, and after 1 and two years; perioperative results; and outcome during follow-up were evaluated. Read More

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http://dx.doi.org/10.1016/j.jvs.2019.06.200DOI Listing