23,878 results match your criteria Renal Failure Chronic and Dialysis Complications

An optimized machine learning framework for predicting intradialytic hypotension using indexes of chronic kidney disease-mineral and bone disorders.

Comput Biol Med 2022 Jun 10;145:105510. Epub 2022 Apr 10.

Department of Nephrology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China. Electronic address:

Intradialytic hypotension (IDH) is the most common acute complication in hemodialysis (HD) sessions and is associated with increased morbidity and mortality in HD patients. To prevent the episode of IDH, it is critical to predict its occurrence. Chronic kidney disease-mineral and bone disorders (CKD-MBD) induce cardiac and vascular calcification, which impairs the compensatory mechanisms of blood pressure during HD. Read More

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A retrospective observational study of patients on maintenance hemodialysis receiving parathyroidectomy by ultrasonic scalpel.

BMC Surg 2022 May 18;22(1):192. Epub 2022 May 18.

Department of Nephrology, Xiangyang Central Hospital, Hubei University of Arts and Science, Xiangyang, Hubei, China.

Background: Secondary hyperparathyroidism (SHPT) remains a common complication in many patients on maintenance hemodialysis. Kidney Disease Improve Global Outcomes (KDIGO) 2017 guidelines suggest that parathyroidectomy (PTX) should be performed in severe SHPT patients with chronic kidney disease stage 3a-stage 5D. In the present study, we observed the efficacy of ultrasonic scalpel for PTX in SHPT patients on maintenance hemodialysis. Read More

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Gestational trophoblastic neoplasm in a patient with end-stage renal failure (ESRF): the challenges and lessons learnt.

BMJ Case Rep 2022 May 18;15(5). Epub 2022 May 18.

Obstetric and Gynaecology, Sarawak General Hospital, Kuching, Sarawak, Malaysia.

Gestational trophoblastic neoplasm (GTN) in end-stage renal failure (ESRF) has not been reported. We reported an unprecedented case of GTN in ESRF from an antecedent partial mole. She had total abdominal hysterectomy and bilateral salpingectomy following the diagnosis as the disease was confined to the uterus. Read More

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Nephrology Considerations in the Management of Durable and Temporary Mechanical Circulatory Support.

Kidney360 2022 Mar 14;3(3):569-579. Epub 2022 Jan 14.

Selzman Institute for Kidney Health, Section of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas.

Durable and temporary mechanical circulatory support (MCS) use is growing for a range of cardiovascular indications. Kidney dysfunction is common in people evaluated for or receiving durable or temporary MCS and portends worse outcomes. This kidney dysfunction can be due to preexisting kidney chronic kidney disease (CKD), acute kidney injury (AKI) related to acute cardiovascular disease necessitating MCS, AKI due to cardiac procedures, and acute and chronic MCS effects and complications. Read More

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Clinical and histological findings at second but not at first kidney biopsy predict end-stage kidney disease in a large multicentric cohort of patients with active lupus nephritis.

Lupus Sci Med 2022 May;9(1)

Unit of Rheumatology, Department of Medicine, DIMED, University of Padua, Padova, Italy.

Objective: To investigate second kidney biopsy as predictor of end-stage kidney disease (ESKD) in active lupus nephritis (LN).

Methods: Patients with biopsy-proven LN (International Society of Nephrology/Renal Pathology Society 2003) who had undergone a second kidney biopsy between January 1990 and December 2018 were included. Clinical and histological findings at first and at second biopsy were analysed with Cox proportional hazard models to predict ESKD, defined as start of kidney replacement therapy. Read More

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The Effect of Non-Pharmacological and Pharmacological Interventions on Measures Associated with Sarcopenia in End-Stage Kidney Disease: A Systematic Review and Meta-Analysis.

Nutrients 2022 Apr 27;14(9). Epub 2022 Apr 27.

Department of Cardiovascular Sciences, University of Leicester, Leicester LE1 7RH, UK.

This systematic review and meta-analysis provides a synthesis of the available evidence for the effects of interventions on outcome measures associated with sarcopenia in end-stage kidney disease (ESKD). Thirteen databases were searched, supplemented with internet and hand searching. Randomised controlled trials of non-pharmacological or pharmacological interventions in adults with ESKD were eligible. Read More

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A case of cholesterol embolization syndrome mimicking rapidly progressive renal failure causing end-stage kidney disease.

Saudi J Kidney Dis Transpl 2021 Sep-Oct;32(5):1489-1494

Department of Nephrology, Command Hospital Air Force, Bengaluru, Karnataka, India.

Cholesterol embolization syndrome is an uncommon complication of coronary angioplasty. Its clinical manifestations are nonspecific and may be ascribed to other causes mimicking vasculitis syndrome. In an appropriate clinical setting, the diagnosis can be confirmed by tissue biopsy. Read More

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Transcatheter mitral valve repair with a mitraclip for severe mitral regurgitation in a patient on hemodialysis.

Saudi J Kidney Dis Transpl 2021 Sep-Oct;32(5):1465-1469

Department of Internal Medicine, Division of Cardiology, St. Marianna University School of Medicine, Kawasaki, Japan.

A 55-year-old male patient undergoing hemodialysis (HD) had shortness of breath, New York Heart Association (NYHA) class IIm (moderate limitation of physical activity) due to chronic heart failure. His past medical history was remarkable for chronic heart diseases and severe functional mitral regurgitation (MR), with an ejection fraction of only 33%. The cardiologist considered this severe MR as the cause of his symptom. Read More

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Chronic renal failure in the brazzaville university hospital center: Epidemiological, clinical and evolutionary aspects.

Saudi J Kidney Dis Transpl 2021 Sep-Oct;32(5):1450-1455

Department of Nephrology, Brazzaville University Hospital, Brazzaville, Congo.

Chronic kidney disease (CKD) is a major global public health problem today. In Congo, we have very little epidemiological data. Our goal is to describe the epidemiological, clinical, therapeutic, and progressive aspects of IRC in Brazzaville. Read More

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Surgical management of secondary hyperparathyroidism in dialysis patients in Senegal.

Saudi J Kidney Dis Transpl 2021 Sep-Oct;32(5):1424-1430

Department of Nephrology, Cheikh Anta Diop University, Dakar, Senegal.

Secondary hyperparathyroidism (SHPT) is a common complication of end-stage renal disease. Surgical management occurs in severe forms and/or unresponsive medical treatment. The aim of this study was to outline the indications of parathyroidectomy and its evolution after surgical approach. Read More

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An experimental study to evaluate the effect of low-intensity intradialytic exercises on serum urea, creatinine, and fatigue of chronic kidney disease patients undergoing hemodialysis.

Saudi J Kidney Dis Transpl 2021 Sep-Oct;32(5):1253-1259

Department of Biostatistics, All India Institute of Medical Science, New Delhi, India.

In chronic kidney disease (CKD) toxins accumulate in the muscles and cause fatigue, mental impairment, and muscle dysfunction (cramps). Exercise results in the opening of capillaries thereby increasing blood flow and allowing greater movement of urea and creatinine from the tissues to the vascular compartment and subsequent removal through dialysis. An experimental study of 64 CKD patients (32 each in experimental and control group), six low-intensity intra-dialytic exercises (IDE) were implemented for experimental group using video demonstration at 90 min after initiation of hemodialysis (HD) repeated thrice at an interval of 10 mins. Read More

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Long-term cardio-vascular risk assessment in chronic kidney disease and kidney transplanted patients following SARS-COV-2 disease: protocol for multi-center observational match controlled trial.

BMC Nephrol 2022 05 6;23(1):176. Epub 2022 May 6.

Department of Internal Medicine, Nephrology and Geriatrics, Grigore T Popa University of Medicine and Pharmacy, Iasi, Romania.

Background: The coronavirus disease (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produced a pandemic since March 2020 by affecting more than 243 million people with more than 5 million deaths globally. SARS-CoV-2 infection is produced by binding to angiotensin-converting enzyme, which among other sites is highly expressed in the endothelial cells of the blood vessels, pericytes and the heart, as well as in renal podocytes and proximal tubular epithelial cells. SARS-CoV-2 and cardiovascular disease (CVD) are interconnected by risk factors association with an increased incidence of the disease and by determining de novo cardiac complications. Read More

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A real-world prospective study on dialysis-requiring acute kidney injury.

PLoS One 2022 5;17(5):e0267712. Epub 2022 May 5.

Clinical and Academic Unit of Nephrology, Hospital Universitário Pedro Ernesto, Faculty of Medical Sciences, Rio de Janeiro State University, Rio de Janeiro, Brazil.

Background: Current information about acute kidney injury (AKI) epidemiology in developing nations derives mainly from isolated centers, with few quality multicentric epidemiological studies. Our objective was to describe a large cohort of patients with dialysis-requiring AKI derived from ordinary clinical practice within a large metropolitan area of an emerging country, assessing the impact of age and several clinical predictors on patient survival across the spectrum of human life.

Methods: We analyzed registries drawn from 170 hospitals and medical facilities in Rio de Janeiro, Brazil, in an eleven-year period (2002-2012). Read More

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3D Echocardiography - A Useful Method for Cardiovascular Risk Assessment in End-Stage Renal Disease Patients.

Physiol Res 2021 Nov;70(Suppl 1):S109-S120

5th Department of Internal Medicine, Comenius University Faculty of Medicine in Bratislava, University Hospital Bratislava, Ružinovská 6, 826 06 Bratislava, Slovakia.

Patients with chronic kidney disease (CKD) have an increased risk of premature mortality, mainly due to cardiovascular causes. The association between hemodialysis and accelerated atherosclerosis has long been described. The ankle-brachial index (ABI) is a surrogate marker of atherosclerosis and recent studies indicate its utility as a predictor of future cardiovascular disease and all-cause mortality. Read More

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November 2021

Tocilizumab and Active Antibody-Mediated Rejection in Kidney Transplantation: A Literature Review.

Front Immunol 2022 14;13:839380. Epub 2022 Apr 14.

Nephrology, Hemodialysis, Apheresis and Kidney Transplantation Department, University Hospital Grenoble, Grenoble, France.

Introduction: Chronic kidney disease (CKD) is a major public-health problem that increases the risk of end-stage kidney disease (ESKD), cardiovascular diseases, and other complications. Kidney transplantation is a renal-replacement therapy that offers better survival compared to dialysis. Antibody-mediated rejection (ABMR) is a significant complication following kidney transplantation: it contributes to both short- and long-term injury. Read More

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Epidemiology and outcomes in patients with anemia of CKD not on dialysis from a large US healthcare system database: a retrospective observational study.

BMC Nephrol 2022 04 30;23(1):166. Epub 2022 Apr 30.

Division of Nephrology and Hypertension, Henry Ford Hospital, Detroit, MI, USA.

Background: Optimal management of anemia of chronic kidney disease (CKD) remains controversial. This retrospective study aimed to describe the epidemiology and selected clinical outcomes of anemia in patients with CKD in the US.

Methods: Data were extracted from Henry Ford Health System databases. Read More

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Zinc and Kidney Disease: A Review.

Iran J Kidney Dis 2022 Mar;16(2):79-87

Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Zinc is the second most abundant essential trace element in the human body with important regulatory functions in cellular and subcellular levels in several tissues. Zinc deficiency is associated with the development and progression of chronic kidney disease (CKD) and its complications. With the progression of CKD to end-stage kidney disease (ESKD) and initiation of dialysis, zinc is further removed from the body, potentiating the zinc deficiency. Read More

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Hypokalaemic quadriparesis in a patient with urinary diversion through Indiana pouch.

BMJ Case Rep 2022 Apr 29;15(4). Epub 2022 Apr 29.

Nephrology, KS Hegde Medical Academy, Mangalore, Karnataka, India.

A man in his 20s, a patient with chronic kidney disease with a baseline estimated glomerular filtration rate of 33 mL/min/1.73 m, who had an Indiana pouch continent urinary diversion procedure done at 6 years of age for bladder exstrophy, presented to the emergency room with sudden-onset progressive quadriparesis over 6 hours with power 1/5 in all the limbs with preserved reflexes. He was fully conscious and oriented, with stable vital signs. Read More

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Food as medicine? Exploring the impact of providing healthy foods on adherence and clinical and economic outcomes.

Explor Res Clin Soc Pharm 2022 Mar 18;5:100129. Epub 2022 Mar 18.

The Marzam Group, USA.

Background: Chronic disease prevalence is increasing. Adherence to dietary guidelines is low (<50%) despite positive impacts in disease progression, clinical outcomes, and medical costs. It is important to summarize the impact of providing medically-tailored meals to patients on adherence rates, clinical outcomes, and potential economic outcomes. Read More

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Low dose sacubitril/valsartan is effective and safe in hemodialysis patient with decompensated heart failure and hypotension: A case report.

Medicine (Baltimore) 2022 Apr 15;101(15):e29186. Epub 2022 Apr 15.

Nephrology Department, Sichuan Provincial People's Hospital, Chengdu, China.

Rationale: Severe heart failure in chronic hemodialysis (HD) patients is a great treatment challenge. Here we reported a chronic HD patient with the lowest ejection fraction reported so far and hypotension who well tolerated and benefited from angiotensin-receptor neprilysin inhibitor (ARNI) treatment.

Patient Concerns: This case was a 67 year old lady with decompensated heart failure and hypotension who was on regular HD. Read More

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Effect of traditional Chinese medicine Bailing capsule on renal anemia in maintenance hemodialysis patients: A protocol for systematic review and meta-analysis.

Medicine (Baltimore) 2022 Apr 15;101(15):e29086. Epub 2022 Apr 15.

Department of Psychiatry, Haibin People's Hospital of Binhai New Area, Binhai New Area, Tianjin, China.

Background: Renal anemia (RA) is one of the most common complications in patients with end-stage renal disease, and it is also one of the reasons for the decline of quality of life and functional status in patients with end-stage renal disease. Traditional treatment methods often fail to achieve satisfactory therapeutic effects, so it is very necessary to find effective adjuvant treatment methods. Bailing capsule (BLC), a traditional Chinese medicine, which has been widely used in the treatment of RA in maintenance hemodialysis patients, but a systematic review of the efficacy and safety of this drug is currently lacking. Read More

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Late venous laceration after inappropriate placement of a left internal jugular hemodialysis catheter: a case report.

J Int Med Res 2022 Apr;50(4):3000605221093305

Department of Nephrology, Zhabei Central Hospital of JingAn District of Shanghai, Shanghai, China.

Central venous catheterization is a necessary and common method of building the circulation pathways of patients with end-stage kidney disease. Venous rupture is a severe and fatal complication of central venous catheterization. We herein present a case of slowly occurring venous rupture after reinsertion of a left internal jugular vein (IJV) catheter. Read More

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Comparison of left ventricular subclinical systolic dysfunction between hemodialysis patients and renal transplant recipients using real time three-dimensional echocardiography.

Echocardiography 2022 May 24;39(5):708-716. Epub 2022 Apr 24.

Department of Cardiology, Tepecik Training and Research Hospital, Izmir, Turkey.

Aims: The relationship between chronic kidney disease and development of heart failure is a well-known clinical entity. Systolic dyssynchrony index (SDI_16) is a new diagnostic tool for detection of subclinical left ventricular (LV) systolic dysfunction by using three-dimensional echocardiography (3DE). We aimed to investigate this parameter in patients with end-stage renal disease who were receiving hemodialysis and patients with renal transplant compared to healthy control subjects. Read More

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Association of plasma neutrophil gelatinase-associated lipocalin and thoracic aorta calcification in maintenance hemodialysis patients with and without diabetes.

BMC Nephrol 2022 04 22;23(1):156. Epub 2022 Apr 22.

Department of Nephrology, The First Affiliated Hospital of Shandong First Medical University (Shandong Provincial Qianfoshan Hospital), No.16766, Jingshi Road, Jinan, 250014, China.

Background: Neutrophil gelatinase-associated lipocalin (NGAL) is not only a bone-derived factor involved in metabolism, but also a biomarker of kidney disease and cardiovascular pathophysiology. We conducted this cross-sectional observational study to explore relationships between plasma NGAL and thoracic aorta calcification (TAC) in maintenance hemodialysis (MHD) patients with and without diabetes.

Methods: Plasma NGAL was measured by ELISA, TAC was evaluated via computed tomography scan using a 3D quantification method or chest radiography aortic arch calcification score. Read More

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Hyperuricemia and diabetes mellitus when occurred together have higher risks than alone on all-cause mortality and end-stage renal disease in patients with chronic kidney disease.

BMC Nephrol 2022 04 22;23(1):157. Epub 2022 Apr 22.

School of Medicine, National Yang-Ming University, Taipei, Taiwan.

Introduction: Hyperuricemia and diabetes mellitus (DM) are associated with increased mortality risk in patients with chronic kidney disease (CKD). Here we aimed to evaluate the independent and joint risks of these two conditions on mortality and end stage kidney disease (ESKD) in CKD-patients.

Methods: This retrospective cohort study enrolled 4380 outpatients (with CKD stage 3-5) with mortality and ESKD linkage during a 7-year period (from 2007 to 2013). Read More

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The Extracellular Mass to Body Cell Mass Ratio as a Predictor of Mortality Risk in Hemodialysis Patients.

Nutrients 2022 Apr 15;14(8). Epub 2022 Apr 15.

Nephrology Department, Hospital Universitario La Princesa, 28006 Madrid, Spain.

The extracellular mass/body cell mass ratio (ECM/BCM ratio) is a novel indicator of nutritional and hydration status in hemodialysis (HD) patients. This study aimed to explore the ECM/BCM ratio as a predictor of mortality risk with nutritional-inflammatory markers in HD patients. A prospective observational study was conducted in 90 HD patients (male: 52. Read More

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Inverse Relationship between Mean Corpuscular Volume and T-Score in Chronic Dialysis Patients.

Medicina (Kaunas) 2022 Mar 30;58(4). Epub 2022 Mar 30.

Department of Orthopedics, Wan Fang Hospital, Taipei Medical University, Taipei 116, Taiwan.

Osteoporosis and anemia are prevalent among chronic kidney disease stage 5D (CKD stage 5D) patients. Osteoblasts are known as the niche cells of hematopoietic stem cells (HSCs) and stimulate HSCs to form blood-cell lineages within bone marrow microenvironments. We hypothesized that an inverse correlation may exist between mean corpuscular volume (MCV), a surrogate for ineffective hematopoiesis, and bone mineral density (BMD) in the CKD stage 5D population. Read More

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Frailty predicts increased risk of reintervention in the 2 years after arteriovenous fistula creation.

J Vasc Access 2022 Apr 21:11297298221088756. Epub 2022 Apr 21.

Concord Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.

Introduction: Frailty is associated with adverse survival and increased hospital use in patients with end-stage kidney disease (ESKD). Dialysis access failure is an important source of morbidity and mortality for these patients. There is limited evidence about the interactions between frailty and haemodialysis access failure. Read More

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Hemodialysis and effect of corrective measures to prevent hypoglycemia.

V Katla R Khyalappa

J Assoc Physicians India 2022 Apr;70(4):11-12

DY Patil Hospital, Kolhapur.

Type 2 diabetes mellitus is the leading cause of end stage renal disease. Chronic kidney disease (CKD) especially end stage renal disease (ESRD) usually require renal replacement therapy and are on maintenance dialysis. Glycemic control is challenging in ESRD because of uremia. Read More

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Deceased Donor Renal Transplantation: 6 Year Experience from a Tertiary Care Center in North India.

J Assoc Physicians India 2022 Apr;70(4):11-12

Sms Medical College and Hospital, New Delhi.

The incident of End stage renal disease (ESRD) is rising rapidly worldwide. Renal transplant is the best modality of treatment, offering a better quality of life and mortality benefit, as compared with long-term dialysis. Very few patients have a live renal transplant donor, for rest, a decreased donor renal transplant is the only alternative. Read More

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