3,980 results match your criteria Renal Failure[Journal]


Renal structural image processing techniques: a systematic review.

Ren Fail 2019 Nov;41(1):57-68

e Department of Electrical Engineering , University of Tabriz , Tabriz , Iran.

Background And Objective: Renal disease, such as nephritis and nephropathy, is very harmful to human health. Accordingly, how to achieve early diagnosis and enhance treatment for kidney disorders would be the important lesion. Nevertheless, the clues from the clinical data, such as biochemistry examination, serological examination, and radiological studies are quite indirect and limited. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1572016DOI Listing
November 2019

Greetings to the readers.

Authors:
Tibor Fülöp

Ren Fail 2019 Nov;41(1):69-71

a Department of Medicine, Division of Nephrology , Medical University of South Carolina , Charleston , SC , USA.

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http://dx.doi.org/10.1080/0886022X.2019.1573499DOI Listing
November 2019

The incidence, risk factors, and clinical outcomes of acute kidney injury (staged using the RIFLE classification) associated with intravenous acyclovir administration.

Ren Fail 2018 Nov;40(1):687-692

b Department of Internal Medicine , Changwon Gyeongsang National University Hospital , Changwon , South Korea.

Intravenous (IV) acyclovir is commonly administered medication for viral infection but is well known for its nephrotoxicity. However, there was no study for incidence, risk factors, and clinical outcomes of acute kidney injury (AKI) associated with IV acyclovir administration. We retrospectively reviewed the medical records of 287 patients who were medicated IV acyclovir from January 2008 to May 2013 in Gyeongsang National University Hospital. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1487866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319461PMC
November 2018
2 Reads

The anti-inflammatory effects of curcumin on renal ischemia-reperfusion injury in rats.

Ren Fail 2018 Nov;40(1):680-686

c General Medicine Center and University of Electronic Science and Technology , Sichuan Academy of Sciences & Sichuan Provincial People's Hospital , Chengdu , China.

The present study aimed to explore the protective mechanism of curcumin-precondition in renal ischemia-reperfusion (I/R) injury. Thirty male SD rats were randomly equally divided into Sham, IRI, and Curcumin groups (n = 10). The model of IRI was induced by clamping the left renal artery for 45 min followed by 24 h reperfusion with the contralateral nephrectomy. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1544565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282432PMC
November 2018
1 Read
0.775 Impact Factor

Hemoglobin targets for the anemia in patients with dialysis-dependent chronic kidney disease: a meta-analysis of randomized, controlled trials.

Ren Fail 2018 Nov;40(1):671-679

a Department of Nephrology , The Third Affiliated Hospital of Sun Yat-sen University , Guangzhou , China.

Background: Anemia is extremely common among dialysis patients and underlies some of the symptoms associated with reduced kidney function, including fatigue, depression, reduced exercise tolerance, and dyspnea.

Objectives: A clearer cognition of the prognosistic impact of hemoglobin (Hb) or hematocrit (Hct) target for the outcomes of dialysis patients is urgent. This article aims to establish the suitable hemoglobin in order to provide clinical guidance. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1532909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282462PMC
November 2018

Effect of atorvastatin on iron metabolism regulation in patients with chronic kidney disease - a randomized double blind crossover study.

Ren Fail 2018 Nov;40(1):700-709

a Department of Nephrology, Hypertension and Kidney Transplantation , Medical University of Lodz, University Hospital and Teaching Center , Lodz , Poland.

Introduction: To determine the effect of 6-month administration of atorvastatin on hepcidin and hemojuvelin levels, inflammatory parameters and iron metabolism in patients with chronic kidney disease (CKD) stages 3 and 4.

Methods: Thirty six statin- and erythropoiesis-stimulating agent-naive patients with CKD stages 3 and 4 and LDL cholesterol ≥100 mg/dl received atorvastatin or placebo for two 6-month periods in a double blind, randomized crossover study. Hepcidin, hemojuvelin, hsCRP, IL-6, hemoglobin, red blood cell distribution width, iron, total iron binding capacity (TIBC), and unsaturated iron binding capacity (UIBC) were measured before and after each treatment period. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1535983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319462PMC
November 2018
1 Read

The logistic organ dysfunction system score predicts the prognosis of patients with alcoholic ketoacidosis.

Ren Fail 2018 Nov;40(1):693-699

b Department of Internal Medicine , Changwon Gyeongsang National University Hospital , Changwon , South Korea.

Alcoholic ketoacidosis (AKA) is occasionally associated with multiple complications leading to death. However, no study has yet evaluated prognostic factors in patients with AKA. It is known that the logistic organ dysfunction system (LODS) score is an objective and useful index to predict the prognosis. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1491405DOI Listing
November 2018
1 Read

Review of the efficacy of AST-120 (KREMEZIN) on renal function in chronic kidney disease patients.

Ren Fail 2019 Nov;41(1):47-56

a Kureha Corporation , Tokyo , Japan.

AST-120 (KREMEZIN®) consists of oral, spherical carbon particles that adsorb uremic toxins and their precursors within the gastrointestinal tract, allowing them to be excreted in the feces. Uremic toxins such as indoxyl sulfate and p-cresyl sulfate are abundant in the blood of chronic kidney disease (CKD) patients and are related to the progression of both CKD and cardiovascular disease. AST-120 was approved in Japan in 1991 followed by Korea (2004), Taiwan (2007) and the Philippines (2010) for treating uremic symptoms and prolonging the time to initiation of dialysis in patients with progressive CKD. Read More

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November 2019
2 Reads

The cartonectin levels at different stages of chronic kidney disease and related factors.

Ren Fail 2019 Nov;41(1):42-46

b Erzurum Regional Research and Training Hospital , Erzurum , Turkey.

Introduction: Cartonectin was defined as a new adipokine released from rat and human adipocyte tissues, which is also known as CORS 26 or CTRP3 protein. Although there are several studies investigating the effects of cartonectin with obesity, anti-inflammatory mechanisms, and cardioprotective effects, there is no study about the effects of cartonectin in patients with chronic kidney disease yet. We aimed to investigate cartonectin levels in predialysis and dialysis patient groups, in other words, at different stages of chronic kidney disease, by comparing with the control group. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1561373DOI Listing
November 2019

Association of sirtuin 1 gene polymorphisms with nephrolithiasis in Eastern chinese population.

Ren Fail 2019 Nov;41(1):34-41

a Department of Nephrology , Shanghai Changhai Hospital , Shanghai , China.

Sirtuin 1 (SIRT1), an NAD-dependent deacylase, has been identified to be associated with renal tubular inflammatory conditions and metabolic disorders, which are risk factors of nephrolithiasis. To further confirm the role of the SIRT1 in kidney stone formation, the expression of SIRT1 was analyzed based on a mouse model and the genetic polymorphisms of SIRT1 gene was compared between patients with kidney stones and controls. The calcium oxalate (CaOx) crystal-induced renal injury model was established to analyzed the expression of SIRT1 in the kidney tissue of both wild-type and ApoE(-/-) mice. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1568258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366414PMC
November 2019
1 Read

The aqueous extract of aged black garlic ameliorates colistin-induced acute kidney injury in rats.

Ren Fail 2019 Nov;41(1):24-33

a Department of Internal Medicine , Gyeongsang National University Changwon Hospital , Changwon , Republic of Korea.

The use of colistin in the treatment of multidrug-resistant Gram-negative bacterial infections is restricted due to nephrotoxicity. We investigated the effects of aged black garlic extract (ABGE) on colistin-induced kidney injury in rats. Rats were assigned to four groups. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1561375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366426PMC
November 2019
1 Read

Effects of prophylactic antibiotics before peritoneal dialysis catheter implantation on the clinical outcomes of peritoneal dialysis patients.

Ren Fail 2019 Nov;41(1):16-23

a Department of Nephrology , Shandong University Qilu Hospital , Jinan , China.

Background: Peritoneal dialysis (PD) related infections, such as peritonitis, are still the main obstacle for the development of PD. Prophylactic antibiotic as one of the interventions to prevent early peritonitis was recommended to use before PD catheter insertion by International Society for Peritoneal Dialysis (ISPD) guidelines, In our hospital, however, since 2012, the prophylactic antibiotics for insertion of PD catheters were not allowed to use because of our hospital's regulation. In order to analyze the outcomes of PD patients without using prophylactic antibiotics before the PD catheter insertion, we compared the PD patients with or without prophylactic antibiotics before PD catheter insertion. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2019.1
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http://dx.doi.org/10.1080/0886022X.2019.1568259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366413PMC
November 2019
5 Reads

Risk factors analysis for hyperuricemic nephropathy among CKD stages 3-4 patients: an epidemiological study of hyperuricemia in CKD stages 3-4 patients in Ningbo, China.

Ren Fail 2018 Nov;40(1):666-671

a Beilun People's Hospital & the Beilun Branch of the First Affiliated Hospital of School of Medicine , Zhejiang University , Ningbo , Zhejiang , China.

Objective: Uric acid (UA) is a risk marker of CKD and SUA level in CKD 3-4 patients closely correlates with hyperuricemic nephropathy (HN) morbidity. This study was designed to evaluate the risk factors for HN in CKD 3-4 patients.

Methods: The 461 CKD 3-4 patients were recruited and all patients were divided into three groups (24 h UUA normal, underexeret, and overproduct type groups) according to the 24 h UUA level after receiving low purine food for five days. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1487859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282434PMC
November 2018
14 Reads

Changes in the diagnosis of glomerular diseases in east China: a 15-year renal biopsy study.

Ren Fail 2018 Nov;40(1):657-664

a Kidney Disease Centre, The First Affiliated Hospital , Zhejiang University School of Medicine , Hangzhou , China.

Background: There have been some gradual changes in the distribution of renal biopsy pathological diagnoses during recent years. This study aimed to show changes in renal disease prevalence in China by investigating 10 patients diagnosed at our Kidney Disease Centre during the last 15 years.

Methods And Results: All patients aged 15-year-old or older who underwent renal biopsy at the First Affiliated Hospital, Zhejiang University, from 2001 to 2015 were enrolled. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1537930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282433PMC
November 2018
4 Reads
0.775 Impact Factor

Inhibitors of the renin-angiotensin system ameliorates clinical and pathological aspects of experimentally induced nephrotoxic serum nephritis.

Ren Fail 2018 Nov;40(1):640-648

a Haemophilia PK & ADME , Novo Nordisk , Frederiksberg , Denmark.

Introduction: Chronic kidney disease (CKD) is a global health concern, but the current treatments only slow down the progression. Thus an improved understanding of the pathogenesis and novel treatments of CKD are needed. The nephrotoxic nephritis (NTN) model has the potential to study the pathogenesis of CKD as it resembles human CKD. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1533867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225365PMC
November 2018
12 Reads

Significance of M2 macrophage in tubulointerstitial disease secondary to primary Sjogren's disease.

Ren Fail 2018 Nov;40(1):634-639

c Department of Nephrology , Clinical Medical College, Yangzhou University , Yangzhou , China.

Objective: M2 Macrophages could improve tubulointerstitial disease in animal models. HIF-1αpromotes macrophage polarization and is involved in tubular injury. The study aims to observe the clinicopathologic significance of M2 macrophage and HIF-1α in tubulointerstitial injury secondary to primary Sjogren's disease. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1518242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225512PMC
November 2018
13 Reads
0.775 Impact Factor

Protective potential of Angelica sinensis polysaccharide extract against ethylene glycol-induced calcium oxalate urolithiasis.

Ren Fail 2018 Nov;40(1):618-627

a The Emergency Center, Gansu Nephro-Urological Clinical Center, Lanzhou University Second Hospital , Lanzhou China.

Purpose: To evaluate a Angelica sinensis polysaccharide aqueous extract as a preventive agent in experimentally induced urolithiasis using in- vitro and vivo models.

Material And Methods: Angelica sinensis polysaccharide was investigated in vitro to determine its antilithiatic effects on the formation and morphology of calcium oxalate (CaOx) crystals and was analyzed in vivo to determine its ability to prevent CaOx urolithiasis in rats subjected to ethylene glycol-induced urolithiasis. Potassium citrate administration was used in the positive control group. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1496935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225371PMC
November 2018
10 Reads

Vegetarian diet may ameliorate uremic pruritus in hemodialysis patients.

Ren Fail 2018 Nov;40(1):514-519

g Division of Nephrology , Asia University Hospital , Taichung , Taiwan.

Objectives: Systemic inflammation has been reported to be associated with uremic pruritus (UP). Although a vegetarian diet can reduce systemic inflammation in hemodialysis patients, the effect of vegetarian diet on UP is not clear. The purpose of the study was to know the possible effects of vegetarian diet on UP. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1512871DOI Listing
November 2018
14 Reads

Impact of acute kidney injury in donors on renal graft survival: a systematic review and Meta-Analysis.

Ren Fail 2018 Nov;40(1):649-656

a Organ Transplant Center, The First Affiliated Hospital , Sun Yat-sen University , Guangzhou , Guangdong , China.

The acute kidney injury (AKI) of deceased donors was an important strategy to address donor shortage. This meta-analysis was conducted to explore the clinical effect of kidney transplantation from donors with AKI. PubMed, Embase, and Cochrane Library were searched through July 2017. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1535982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225519PMC
November 2018
12 Reads

Reducing the occurrence rate of catheter dysfunction in peritoneal dialysis: a single-center experience about CQI.

Ren Fail 2018 Nov;40(1):628-633

a Department of Nephrology , The Third Xiangya Hospital of Central South University , Changsha , China.

To reduce the occurrence rate of peritoneal dialysis (PD) catheter dysfunction caused by catheter displacement or plugging, this study screened all patients with peritoneal dialysis catheterization from 2002 to 2015 from the Third Xiangya Hospital of Central South University. There were 256 patients before continuous quality improvement (CQI) (from 2002 to 2007) and 813 patients after CQI (from 2008 to 2015). The occurrence rate of catheter dysfunction was 5. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1515084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225513PMC
November 2018
14 Reads
0.780 Impact Factor

Wider intraoperative glycemic fluctuation increases risk of acute kidney injury after pediatric cardiac surgery.

Ren Fail 2018 Nov;40(1):611-617

c Department of Occupational and Environmental Health , Public Health School, Central South University , Changsha , China.

Objective: The association between poor intraoperative glycemic control and postoperative acute kidney injury (AKI) in adult cardiac surgery has been observed, but data in the pediatrics remain unknown. We performed a hypothesis that intraoperative hyperglycemia and/or wider glycemic fluctuation were associated with the incidence of postoperative AKI in pediatric cardiac surgery.

Methods: A retrospective study was performed in pediatrics who underwent cardiac surgery from 2013 to 2016. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
Publisher Site
http://dx.doi.org/10.1080/0886022X.2018.1532908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225368PMC
November 2018
9 Reads

Baicalein protects renal tubular epithelial cells againsthypoxia-reoxygenation injury.

Ren Fail 2018 Nov;40(1):603-610

b Department of Nephrology , The First Affiliated Hospital of Shantou University Medical College , Shantou , China.

Background: To investigate the protective effects and mechanism of baicalein (BAI), a naturally occurring flavonoid, against hypoxia-reoxygenation (HR) injury in renal tubular epithelial cells (HK-2).

Methods: Cultured human renal proximal tubular cell line HK-2 was exposed to 24 h of hypoxia (5% CO, 1% O, and 94% N), followed by 12 h of reoxygenation (5% CO, 21% O, and 74% N). HK-2 cells were divided into three groups: control, HR, and HR-BAI (0. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1532910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225411PMC
November 2018

The influence of environmental factors on clinical pathological changes of patients with immunoglobulin A nephropathy from different areas of China.

Ren Fail 2018 Nov;40(1):597-602

e Pure and Applied Biochemistry , Lund University , Lund , Sweden.

Objectives: The effects of regional characteristics of IgAN patients in different areas of China were investigated.

Methods: Patients who were identified to have primary IgAN by renal biopsy diagnosis were recruited both from Shaanxi province hospital of traditional Chinese medicine and Guangdong province hospital of traditional Chinese medicine. Besides renal histopathology data, a number of clinical and laboratory data were collected. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1532907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211320PMC
November 2018
4 Reads

Decreased expression of transforming growth factor-β1 and α-smooth muscle actin contributes to the protection of lotensin against chronic renal failure in rats.

Ren Fail 2018 Nov;40(1):583-589

a Department of Nephrology , The First Hospital of Jilin University , Changchun , China.

Background: Lotensin has been shown to have a protective function in the early stage of chronic renal failure. However, its role in the intermediate and late stages of chronic renal failure remains largely unknown. The present study aimed to investigate the role and underlying mechanism of lotensin in advanced chronic kidney disease. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1496934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211277PMC
November 2018
9 Reads

The association between the red cell distribution width and diabetic nephropathy in patients with type-2 diabetes mellitus.

Ren Fail 2018 Nov;40(1):590-596

a Division of Nephrology , West China Hospital of Sichuan University , Chengdu , China.

Background: Red cell distribution width (RDW) has been reported to be involved in metabolic syndrome and cardiovascular events. Patients with diabetic nephropathy (DN) are often found to be with high level of RDW. The aim of this study was to explore whether RDW was associated with DN severity and progression in patients with type-2 diabetes mellitus (T2DM). Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1532906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211258PMC
November 2018
17 Reads
0.780 Impact Factor

The contribution of genetic variants of SLC2A1 gene in T2DM and T2DM-nephropathy: association study and meta-analysis.

Ren Fail 2018 Nov;40(1):561-576

b Department of Biomathematics , University of Thessaly School of Medicine , Larissa , Greece.

An association study was conducted to investigate the relation between 14 variants of glucose transporter 1 gene (SLC2A1) and the risk of type 2 diabetes (T2DM) leading to nephropathy. We also performed a meta-analysis of 11 studies investigating association between diabetic nephropathy (DN) and SLC2A1 variants. The cohort included 197 cases (T2DM with nephropathy), 155 diseased controls (T2DM without nephropathy) and 246 healthy controls. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1496931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201811PMC
November 2018
8 Reads

Peritoneal dialysis in Sichuan province of China - report from the Chinese National Renal Data System.

Ren Fail 2018 Nov;40(1):577-582

a Renal Department and Nephrology Institute , Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China , Chengdu , China.

Background: Peritoneal dialysis (PD) is one of the important treatment strategies for end stage renal disease (ESRD). In this study, we aimed to study the patients on PD of Sichuan province in the registry system and to explore the risk factors.

Methods: This was a retrospective study based on data from the Chinese National Renal Data System (CNRDS). Read More

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http://dx.doi.org/10.1080/0886022X.2018.1496933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201772PMC
November 2018
2 Reads
0.780 Impact Factor

Proteomics investigation of the changes in serum proteins after high- and low-flux hemodialysis.

Ren Fail 2018 Nov;40(1):506-513

c Department of Nephritic Medicine , Second Affiliated Hospital of Dalian Medical University , Dalian , China.

Purpose: This study aimed to use proteomics methods to investigate the changes in serum protein levels after high- and low-flux hemodialysis (HD).

Methods: Before and after HD, serum samples were obtained from two selected patients who were treated with a Polyflux 140 H high-flux dialyzer and a Polyflux 14 L low-flux dialyzer during two continuous therapy sessions. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) was performed to identify the proteins. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1491406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179064PMC
November 2018
17 Reads

Effect of apigenin on apoptosis induced by renal ischemia/reperfusion injury in vivo and in vitro.

Ren Fail 2018 Nov;40(1):498-505

a Department of Urology , The First Affiliated Hospital of Anhui Medical University , Hefei , PR China.

Objectives: This study aims to investigate the effects and molecular mechanisms of apigenin (ApI) on renal ischemia/reperfusion (I/R) injury in vivo and in vitro.

Methods: In vivo, the left renal artery was clamped for 45 min and the right kidney was removed to study renal I/R injury on Sprague-Dawley (SD) rats. ApI was injected at 60 min before renal ischemia. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1497517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171452PMC
November 2018
4 Reads
0.780 Impact Factor

Association between MPO-463G > A polymorphism and chronic kidney disease: a meta-analysis.

Ren Fail 2018 Nov;40(1):541-546

a Department of Urology Surgery , The First Affiliated Hospital of Xiamen University , Xiamen , Fujian , China.

Background/objective: Previous studies have shown that MPO -463G > A (rs2333227) might be associated with chronic kidney disease (CKD) susceptibility, but sample sizes of those studies are relatively small. Hence, we decided to perform a meta-analysis to evaluate the association. Methods/main results: Two investigators search databases systematically and independently. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1499529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171445PMC
November 2018
14 Reads
0.780 Impact Factor

Which is the most powerful adverse factor for autogenous access patency between diabetes and high arterial calcification burden?

Ren Fail 2018 11;40(1):455-457

a Department of Vascular Surgery , "Democritus" University of Thrace, University General Hospital of Alexandroupolis , Alexandroupolis , Greece.

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http://dx.doi.org/10.1080/0886022X.2018.1497518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171449PMC
November 2018
2 Reads

Association between renal damage markers and carotid atherosclerosis in Afro-descendants with hypertension belonging to a minority ethnic group from Brazil.

Ren Fail 2018 Nov;40(1):483-491

a Postgraduate Program of Health Science, Federal University of Maranhão , São Luís , Brazil.

Ethnicity appears to play an important role in the prevalence and severity of hypertension, renal disease, and atherosclerosis. A cross-sectional study was conducted, including 206 Afro-descendants with hypertension, living in the remaining quilombo communities. These subjects underwent a carotid intima-media thickness (CIMT) assessment. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1496932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171460PMC
November 2018
4 Reads

Clinical and pathologic characteristics of pauci-immune anti-myeloperoxidase antibody associated glomerulonephritis with nephrotic range proteinuria.

Ren Fail 2018 Nov;40(1):554-560

a Department of Nephrology , Tianjin Medical University General Hospital , Tianjin , China.

Background: Heavy proteinuria in antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis (GN) is usually considered to be associated with immune deposits in renal biopsy. Nephrotic ANCA GN without immune deposits (pauci-immune) is rare and has not been studied specially. In this study characteristics of these patients are to be investigated. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1487865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171425PMC
November 2018
4 Reads
0.780 Impact Factor

Serum NGAL and FGF23 may have certain value in early diagnosis of CIN.

Ren Fail 2018 Nov;40(1):547-553

a Department of Nephropathy , Xiangya Hospital Central-South University , Changsha , Hunan 410008 , China.

Aims: This study aimed to assess whether neutrophil gelatinase-associated lipocalin (NGAL) and fibroblast growth factor 23 (FGF23) could be reliable biomarkers for early diagnosis of contrast-induced nephropathy (CIN).

Methods: 202 patients who underwent percutaneous coronary intervention (PCI) were included in the research. All subjects were divided into CIN group and non-CIN group. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1487860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171456PMC
November 2018
16 Reads

The long non-coding RNA MALAT1 is increased in renal ischemia-reperfusion injury and inhibits hypoxia-induced inflammation.

Ren Fail 2018 Nov;40(1):527-533

a Department of Nephrology , The Ninth People's Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , China.

Background: To investigate the expression of long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in renal ischemia-reperfusion injury and explore its role in acute kidney injury.

Methods: 18 mice were randomly divided into a sham operation group (Sham) and an ischemia-reperfusion group (IR) in which animals were sacrificed at 6 h or 12 h after surgery. The kidneys were harvested to measure the expression of MALAT1 mRNA. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1487863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171433PMC
November 2018
4 Reads
0.780 Impact Factor

Changes in the inflammatory and oxidative stress markers during a single hemodialysis session in patients with chronic kidney disease.

Ren Fail 2018 Nov;40(1):534-540

a Department of Nephrology , Sri Venkateswara Institute of Medical Sciences , Tirupati, India.

Background: Cardiovascular disease (CVD) is a common cause of morbidity and mortality in end-stage renal disease (ESRD) patients on hemodialysis (HD) among whom it is 5-20 times higher than in the general population. Some of the nontraditional risk factors such as oxidative stress and inflammation are related to the progress of CVD in HD patients. Several, but not all studies, reported that inflammatory and oxidative stress markers are increased during a single session of HD, mimicking changes that occur during acute immune activation. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1487857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171457PMC
November 2018
4 Reads
0.780 Impact Factor

Clinical and genetic analysis of distal renal tubular acidosis in three Chinese children.

Ren Fail 2018 Nov;40(1):520-526

a Department of Nephrology , Children's Hospital of Fudan University , Shanghai , China.

Objective: Primary distal renal tubular acidosis (dRTA) is a rare genetic disease characterized by distal tubular dysfunction leading to metabolic acidosis and alkaline urine. Growth retardation is a major concern in these children. The disease is caused by defects in at least three genes (SLC4A1, ATP6V0A4, and ATP6V1B1) involved in urinary distal acidification. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1487858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147104PMC
November 2018
12 Reads

The protective effects of rapamycin on cell autophagy in the renal tissues of rats with diabetic nephropathy via mTOR-S6K1-LC3II signaling pathway.

Ren Fail 2018 Nov;40(1):492-497

a Department of Nephrology , Shandong University Qilu Hospital , Jinan , P.R. China.

Background: Previous studies have shown that podocyte autophagy is an important trigger for proteinuria and glomerulosclerosis. The mammalian rapamycin target protein (mTOR) occupies a pivotal position in the autophagy pathway. In this study, we planned to clarify the mechanism of mTOR regulation of podocyte autophagy and the effect of rapamycin (RAPA). Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1489287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136383PMC
November 2018
11 Reads
0.775 Impact Factor

Serum phosphate level at initiation of dialysis is associated with all-cause mortality: a multicenter prospective cohort study.

Ren Fail 2018 Nov;40(1):475-482

c Fujita Health University School of Medicine , Toyoake , Aichi , Japan.

Introduction: As glomerular filtration rate (GFR) decreases, serum phosphate level increases. Previous reports indicated that serum phosphate level was associated with mortality in patients on dialysis. However, few reports have examined the association using dialysis initiation as the baseline period. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1499530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116670PMC
November 2018
3 Reads

Whortleberry protects kidney against the cisplatin-induced nephrotoxicity: an experimental study.

Ren Fail 2018 Nov;40(1):466-474

g Biochemistry Department , Recep Tayyip Erdogan University School of Medicine , Rize , Turkey.

Purpose: This study investigated the antioxidant effects of whortleberry against cisplatin-induced nephrotoxicity in rats.

Material And Methods: This study included 48 female Sprague-Dawley rats weighing 263.68 ± 8. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1500292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104611PMC
November 2018
18 Reads

Low-intensity pulsed ultrasound in combination with SonoVue induces cytotoxicity of human renal glomerular endothelial cells via repression of the ERK1/2 signaling pathway.

Ren Fail 2018 Nov;40(1):458-465

e Medical Research Center, Shandong Provincial Qianfoshan Hospital, Shandong University , Jinan , China.

Objectives: Low-intensity pulsed ultrasound (LIPUS) and SonoVue have been used widely for diagnosis and therapeutic treatment. The effects of LIPUS and SonoVue on the microvascular system and underlying molecular mechanisms have not been established.

Methods: Cultured human renal glomerular endothelial cells (HRGECs) were treated with 5-min ultrasonic irradiation, 20% SonoVue or the combination of both treatments. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1487868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104615PMC
November 2018
4 Reads

3,3'-Diindolylmethane ameliorates renal fibrosis through the inhibition of renal fibroblast activation in vivo and in vitro.

Ren Fail 2018 Nov;40(1):447-454

c Department of Oncology , Renmin Hospital of Wuhan University , Wuhan , China.

3,3'-Diindolylmethane (DIM), a natural acid condensation extracted from cruciferous plants, exhibits anti-fibrotic effects in hepatic and cardiac fibrosis models. The effects of DIM on renal fibrosis, however, are unclear. This study aimed to explore the protective effects of DIM on renal fibrosis. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1490322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095015PMC
November 2018
3 Reads

Urinary protein and renal prognosis in idiopathic membranous nephropathy: a multicenter retrospective cohort study in Japan.

Ren Fail 2018 Nov;40(1):435-441

c Department of Nephrology , Nagoya University Graduate School of Medicine , Nagoya , Japan.

Background: Several studies have revealed a relationship between proteinuria and renal prognosis in idiopathic membranous nephropathy (IMN). The benefit of achieving subnephrotic proteinuria (<3.5 g/day), however, has not been well described. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1487864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070990PMC
November 2018
5 Reads

Risk factors for BK virus infection in living-donor renal transplant recipients: a single-center study from China.

Ren Fail 2018 Nov;40(1):442-446

a National Clinical Research Center of Kidney Diseases, Jinling Hospital , Medical School of Nanjing University , Nanjing , China.

Objectives: BK virus (BKV) infection has become one of the main complications in renal transplant recipients (RTRs) with the arrival of newer potent immunosuppressive agents. However, reports on the epidemiology of BKV infection and risk factors in Chinese population after renal transplantation are scarce.

Methods: From June 2015 to July 2016, living-donor renal transplant recipients (LDRTRs) who routinely received the quantitative BKV DNA testing of urine and plasma samples using quantitative real-time polymerase chain reaction (PCR) for the first time after transplantation were selected, while dialysis patients and healthy living donors during that period served as controls. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1489843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070965PMC
November 2018
15 Reads

Safety and efficacy of retrograde intrarenal surgery for the treatment of renal stone in solitary kidney patients.

Ren Fail 2018 Nov;40(1):390-394

a Department of Urology, Fifth Affiliated Hospital , Guangzhou Medical University , Guangzhou , Guangdong , China.

Purpose: We present our experience of retrograde intrarenal surgery (RIRS) for the treatment of renal stones in patients with solitary kidneys and evaluate the safety and efficacy of this treatment modality.

Materials And Methods: Between March 2011 and July 2015, the clinical records of 60 patients with renal stones in solitary kidneys who underwent RIRS were retrospectively reviewed. Demographic characteristics, preoperative urinary culture, blood biochemistry, stone location, and surface area were documented. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1487861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062886PMC
November 2018
5 Reads

Are there any new reliable markers to detect renal injury in obese children?

Ren Fail 2018 Nov;40(1):416-422

a Department of Pediatrics , Ministry of Health, Bağcılar Training and Research Hospital , Istanbul , Turkey.

Aim: The aim of this study was to examine the serum and urine levels of kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL), osteopontin (OPN), matrix metalloproteinase-9 (MMP-9), and serum Cystatin-C to determine the renal effect of obesity in obese children.

Methods: Seventy-two obese and 35 non-obese healthy children were included in this study. Blood pressure (BP) was evaluated with office measurement. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1489284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060377PMC
November 2018
13 Reads

N-acetylcysteine suppresses colistimethate sodium-induced nephrotoxicity via activation of SOD2, eNOS, and MMP3 protein expressions.

Ren Fail 2018 Nov;40(1):423-434

g Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine , Bezmialem Vakıf University , Istanbul , Turkey.

Objective: To investigate the molecular mechanisms of colistimethate sodium-induced nephrotoxicity and the protective effect of N-acetylcysteine (NAC) against nephrotoxicity.

Methods: Twenty-eight Wistar rats were divided into four groups comprised of control, colistin, NAC, and colistin-NAC co-treatment, respectively. Serum creatinine and urine N-acetyl-β-d-glucosaminidase (NAG) levels were measured at different time intervals. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1489286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060374PMC
November 2018
4 Reads

Clinical characteristics of sepsis-induced acute kidney injury in patients undergoing continuous renal replacement therapy.

Ren Fail 2018 Nov;40(1):403-409

a Department of Internal Medicine, Division of Nephrology , Presbyterian Medical Center , Jeonju , Korea.

Objective: The aim of this study was to investigate the clinical characteristics of sepsis-induced acute kidney injury (AKI) in patients undergoing continuous renal replacement therapy (CRRT).

Methods: From 2011 to 2015, we enrolled 340 patients who were treated with CRRT for sepsis at the Presbyterian Medical Center. In all patients, CRRT was performed using the PRISMA platform. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1489288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052425PMC
November 2018
12 Reads

Influence of uridine diphosphate-glucuronosyltransferases (1A9) polymorphisms on mycophenolic acid pharmacokinetics in patients with renal transplant.

Ren Fail 2018 Nov;40(1):395-402

b Department of Nephrology , Istanbul Faculty of Medicine, Istanbul University , Istanbul , Turkey.

Background: There are differences in pharmacokinetic of mycophenolic acid among individuals. The UGT1A9 enzyme is of special interest since it is the main enzyme involved in the glucuronidation of MPA. Single nucleotide polymorphisms in the UGT1A9 gene may be responsible for individual differences in the pharmacokinetics of MPA. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1489285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052413PMC
November 2018
7 Reads

Acute renal involvement in organophosphate poisoning: histological and immunochemical investigations.

Ren Fail 2018 Nov;40(1):410-415

h Department of Physiology, Faculty of Medicine , Ordu University , Ordu , Turkey.

Purpose: Today, the long-term effects of partial exposure of cholinesterase on the kidney continue to be a research topic. In this study, we aimed to histopathologically investigate the possible effect of acute toxicity due to fenthion, an organophosphate (OP) compound, on the kidneys.

Methods: In all, 21 rats were randomly divided into three groups. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1489289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052427PMC
November 2018
13 Reads