4,010 results match your criteria Renal Failure[Journal]


The effectiveness of cinacalcet: a randomized, open label study in chronic hemodialysis patients with severe secondary hyperparathyroidism.

Ren Fail 2019 Nov;41(1):326-333

a Division of Nephrology, Department of Medicine, Faculty of Medicine, King Chulalongkorn Memorial Hospital , Chulalongkorn University , Bangkok , Thailand.

Background: Secondary hyperparathyroidism (SHPT) is associated with high incidences of cardiovascular disease, bone fracture, and mortality. This study was conducted to demonstrate the effectiveness of cinacalcet treatment on chronic kidney disease-mineral bone disorder (CKD-MBD) markers in chronic hemodialysis patients with severe SHPT.

Methods: In phase 1, 30 adult HD patients were randomized to cinacalcet or control groups for 12 weeks to explore the achievement of >30% reduction of iPTH. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1562356DOI Listing
November 2019
1 Read

Autophagy activity and expression pattern of autophagy-related markers in the podocytes of patients with lupus nephritis: association with pathological classification.

Ren Fail 2019 Nov;41(1):294-302

a Department of Nephrology , Zhejiang Provincial People's Hospital , Hangzhou , China.

Objective: To identify the significance of autophagy in lupus nephritis (LN).

Methods: The number of autophagosomes in podocytes was counted and the expression of multiple molecular markers associated with autophagy was evaluated in LN specimens: in renal biopsy specimens from 90 patients with LN and 15 healthy controls, autophagosomes in podocytes were counted using transmission electron microscopy and the expression levels of four autophage related proteins including Beclin-1, microtubule-associated protein light chain 3 (LC3), autophagy-related gene 7 (Atg7), and UNC-51-like kinase 1 (ULK1) were measured using immunohistochemistry.

Results: The number of autophagosomes in patients with LN types III, IV, and combined V-IV type were significantly higher than in controls (p < 0. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1598432DOI Listing
November 2019

Prevalence of coronary artery calcification and its association with mortality, cardiovascular events in patients with chronic kidney disease: a systematic review and meta-analysis.

Ren Fail 2019 Nov;41(1):244-256

a Department of Nephrology , The First Affiliated Hospital of Anhui Medical University , Hefei , China.

Purpose: To date, the prevalence and prognostic role of coronary artery calcification (CAC) in patients with chronic kidney disease (CKD) have been investigated in several studies, but have yielded conflicting results. The aim of this meta-analysis is to derive a more precise estimation of CAC prevalence in CKD patients and its association with cardiovascular events and mortality.

Methods: The relevant literature was identified and evaluated from inception until July 2018 through multiple search strategies on PubMed, Embase, and Web of Science. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1595646DOI Listing
November 2019
2 Reads

Neutrophil/lymphocyte ratio elevation in renal dysfunction is caused by distortion of leukocyte hematopoiesis in bone marrow.

Ren Fail 2019 Nov;41(1):284-293

a Division of Pharmaceutical Therapeutics, Department of Pharmacy, School of Pharmacy , Hyogo University of Health Sciences , Kobe , Japan.

Objective: We investigate the mechanism of neutrophil/lymphocyte ratio (NLR) elevation, a useful prognostic marker in patients with cardiovascular diseases (CVDs).

Methods: In this clinical study, we retrospectively searched for factors associated with NLR elevation in cardiovascular outpatients. In animal experiments using mice with adenine-induced nephropathy, we further examined the hematopoietic process in bone marrow and explored the mechanism of NLR elevation. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1597736DOI Listing
November 2019

The association between chronic musculoskeletal pain and clinical outcome in chronic kidney disease patients: a prospective cohort study.

Ren Fail 2019 Nov;41(1):257-266

a Division of Nephrology , Chang Gung Memorial Hospital , Keelung , Taiwan.

Background And Objectives: Chronic musculoskeletal (MS) pain is common in chronic kidney disease (CKD) patients. The association of chronic MS pain and CKD progression has not yet been established.

Method: We conducted a prospective cohort study to evaluate the association of chronic MS pain and CKD progression of pre-dialysis CKD patients. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1596817DOI Listing
November 2019

The incidence of acute kidney injury following cardiac arrest and cardiopulmonary resuscitation in a rat model.

Ren Fail 2019 Nov;41(1):278-283

a Department of Critical Care Medicine , Second Affiliated Hospital of Guangxi Medical University , Nanning , P.R. China.

Objective: In the current study, we investigated the incidence of acute kidney injury (AKI) induced by cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) and whether such an AKI can recover spontaneously in rats.

Methods: We used transesophageal alternating current stimulation to establish 7 min of CA rat model followed by conventional CPR. The experimental rats were randomly divided into three groups (n = 20 per group) according to the different time points after restoration spontaneous circulation (ROSC): the ROSC 24 h, ROSC 48 h, and ROSC 72 h group. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2019.1
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http://dx.doi.org/10.1080/0886022X.2019.1596819DOI Listing
November 2019
1 Read

The prominent impairment of liver/intestinal cytochrome P450 and intestinal drug transporters in sepsis-induced acute kidney injury over acute and chronic renal ischemia, a mouse model comparison.

Ren Fail 2019 Nov;41(1):314-325

c Center of Excellence in Immunology and Immune-mediated Diseases , Chulalongkorn University , Bangkok , Thailand.

Drug dosing adjustment in sepsis-induced acute kidney injury (sepsis-AKI) is currently adjusted based on renal function. Sepsis is a multiorgan injury, and thus, drug metabolism in sepsis-AKI might be interfered by non-renal factors such as changes in functions of drug-metabolizing enzymes in the liver and functions of intestinal drug transporters. We compared the defect on mouse CYP3A11 (human CYP3A4 representative) in liver and intestine along with several intestinal drug transporters (MDR1a, MRP2, and OATP3) in three mouse models; chronic ischemic reperfusion injury (Chr I/R; 4-week), acute ischemic reperfusion injury (Acute I/R; 24-h), and cecal ligation and puncture (CLP; 24-h) as representative of sepsis-AKI. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1602054DOI Listing
November 2019
1 Read

Association of Staphylococcus nasal colonization and HIV in end-stage renal failure patients undergoing peritoneal dialysis.

Ren Fail 2019 Nov;41(1):303-313

b Inkosi Albert Luthuli Central Hospital , Durban , South Africa.

Introduction: Staphylococcal infections can cause significant morbidity in patients undergoing dialysis. This study evaluated the effects of HIV infection on nasal carriage of Staphylococcus aureus, staphylococcal peritonitis, and catheter infection rates in patients with end-stage renal failure managed with continuous ambulatory peritoneal dialysis (CAPD).

Methods: Sixty HIV-positive and 59 HIV-negative CAPD patients were enrolled and followed up for up to 18 months. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2019.1
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http://dx.doi.org/10.1080/0886022X.2019.1598433DOI Listing
November 2019
1 Read

Comparison of anti-peritoneal fibrotic effects between an mTORC1-specific blocker and a PI3K/mTOR dual-blocker.

Ren Fail 2019 Nov;41(1):267-277

a Department of Nephrology, Institute of Nephrology, Ruijin Hospital , Shanghai Jiaotong University School of Medicine , Shanghai , China.

Objective: To compare the anti-peritoneal fibrotic effects between a mammalian target of rapamycin complex 1-specific blocker and a phosphatidyl-inositol 3-kinase/mammalian target of rapamycin dual-blocker.

Methods: A total of 40 male Sprague-Dawley rats were randomly divided into five groups with eight animals per group. The normal group (N group) did not receive any intervention. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1596818DOI Listing
November 2019

Gender-specific association between uric acid level and chronic kidney disease in the elderly health checkup population in China.

Ren Fail 2019 Nov;41(1):197-203

a Department of Nephrology , Affiliated Yijishan Hospital, Wannan Medical College , Wuhu , China.

Objective: To evaluate the association between serum uric acid (SUA) levels with CKD in elderly health checkup population and explore the gender difference.

Methods: A total of 4242 subjects were included in the cross-sectional study. All of the subjects participated in the annual checkup between June 2016 and June 2017. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2019.1
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http://dx.doi.org/10.1080/0886022X.2019.1591994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461085PMC
November 2019
2 Reads

Label-free quantitative proteomics identifies Smarca4 is involved in vascular calcification.

Ren Fail 2019 Nov;41(1):220-228

a Department of Nephrology , Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China , Chengdu , China.

Vascular calcification (VC) is a pathological process characterized by abnormal deposition of calcium phosphate, hydroxyapatite and other mineral substances in the vascular wall. Hyperphosphorus is an important risk factor associated with VC in the general population and patients with chronic kidney disease (CKD). However, there is still a lack of early biomarkers for hyperphosphorus induced VC. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1591997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461080PMC
November 2019
1 Read
0.775 Impact Factor

Glomerular expression of matrix metalloproteinases in systemic lupus erythematosus in association with activity index and renal function.

Ren Fail 2019 Nov;41(1):229-237

f Department of Nephrology , University Hospital of Alexandroupoli , Alexandroupolis , Greece.

Purpose: The aim of this study was to examine the expression of matrix metalloproteinases (MMPs) MMP-1, MMP-2, MMP-3, MMP-9, and their specific tissue inhibitor TIMP-1 in kidney biopsies of patients with lupus nephritis (LN) and to investigate the relationship between MMPs, activity index, and renal function at the time of kidney biopsy.

Methods: We performed immunohistochemistry with monoclonal antibodies against MMP-1, MMP-2, MMP-3, MMP-9, and TIMP-1 in 58 kidney-biopsy specimens with LN (according to the 2004 ISN/RPS classification) and eight specimens from normal kidney tissue. We used clinical data of 36 patients at the time of kidney biopsy to evaluate the association between MMPs expression and renal function. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461111PMC
November 2019
1 Read

Omega-3 fatty acid decreases oleic acid by decreasing SCD-1 expression in the liver and kidney of a cyclosporine-induced nephropathy rat model.

Ren Fail 2019 Nov;41(1):211-219

a Department of Internal Medicine, Dong-A University , Busan , Republic of Korea.

Aim: Stearoyl-CoA desaturase (SCD)-1 and elongase-6 (Elovl-6) are associated with fatty acid (FA) synthesis. We evaluated the effect of omega-3 FA on erythrocyte membrane FA contents through SCD-1 and Elovl-6 expression in the liver and kidney of a cyclosporine (CsA)-induced rat model.

Methods: Male Sprague Dawley rats were divided into control, CsA, and CsA treated with omega-3 FA groups. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1591996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450600PMC
November 2019
1 Read

Refractory secondary hyperparathyroidism in waiting list for parathyroidectomy: who we should operate first in a quaternary hospital in Brazil regarding survival.

Ren Fail 2019 Nov;41(1):183-189

b Rio de Janeiro State University, Medical Sciences Post-Graduation Program , Rio de Janeiro , Brazil.

Background: Few centers in Brazil perform parathyroidectomy (PTX) for recalcitrant secondary hyperparathyroidism (SHPT) generating a long queue. There is little data regarding prioritize criteria besides chronological order and survival.

Objectives: To determine the difference of clinical and laboratory factors between PTX patients and those who remained in the line despite the need for surgery and their survival. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1590210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450528PMC
November 2019
1 Read

Protective effect of bone marrow mesenchymal stem cells modified with klotho on renal ischemia-reperfusion injury.

Ren Fail 2019 Nov;41(1):175-182

d Department of Urology , The Institution of Urology, West China Hospital, Sichuan University , Chengdu , China.

Objective: To detect the combination protective effect of bone marrow mesenchymal stem cells (BMSCs) and Klotho gene on the renal ischemia-reperfusion injury (RIRI).

Methods: BMSCs isolated from rats were transfected with Klotho gene to form BMSC. We injected BMSC to allogenic rat RIRI model. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1588131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450585PMC
November 2019
1 Read

Incidence, risk factors, and clinical outcomes of acute kidney injury associated with acute pyelonephritis in patients attending a tertiary care referral center.

Ren Fail 2019 Nov;41(1):204-210

b Department of Internal Medicine , Changwon Gyeongsang National University Hospital , Changwon , Republic of Korea.

Acute kidney injury (AKI) associated with acute pyelonephritis (APN) rarely has been reported. The aim of this study was to evaluate the incidence and risk factors of AKI associated with APN. We retrospectively reviewed the medical records of 403 patients over 18-year old age hospitalized for APN management from October 2009 to September 2014 in tertiary care referral center. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1591995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450601PMC
November 2019
4 Reads

The influence of glycemic status on the performance of cystatin C for acute kidney injury detection in the critically ill.

Ren Fail 2019 Nov;41(1):139-149

a The Second School of Clinical Medicine , Southern Medical University , Guangzhou , People's Republic of China.

Objective: Serum cystatin C (sCysC) used clinically for detecting early acute kidney injury (AKI) was reported to be independently associated with hemoglobin (HbA1c) levels, diabetes, and prediabetes. We aimed to assess the influence of HbA1c levels, diabetes, or prediabetes on the performance of sCysC for AKI detection in critically ill adults.

Methods: A prospective observational study was conducted in a mixed medical-surgical intensive care unit (ICU). Read More

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http://dx.doi.org/10.1080/0886022X.2019.1586722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450510PMC
November 2019
1 Read

High neutrophil/lymphocyte ratio is associated with poor renal outcomes in Japanese patients with chronic kidney disease.

Ren Fail 2019 Nov;41(1):238-243

a Department of Medicine and Clinical Science, Graduate School of Medical Sciences , Kyushu University , Higashi-ku , Japan.

Background: Several studies have shown that the neutrophil/lymphocyte ratio (NLR) is a marker that reflects the state of systemic inflammation. A high NLR was reported to be associated with cardiovascular events and mortality. However, little is known about the association between NLR and kidney disease progression in patients with chronic kidney disease (CKD). Read More

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http://dx.doi.org/10.1080/0886022X.2019.1595645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450582PMC
November 2019
1 Read

Renoprotective effect of oral rehydration solution III in exertional heatstroke rats.

Ren Fail 2019 Nov;41(1):190-196

a Department of Nephrology , General Hospital of Northern Theater Command , Liaoning , China.

Aim: Exertional heastroke (EHS) can lead to acute kidney injury. Oral rehydration solution III (ORS III), recommended by WHO in 2004, is used to rehydrate children with gastroenteritis. This study aimed to characterize the renoprotective effect of ORS III in EHS rats. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2019.1
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http://dx.doi.org/10.1080/0886022X.2019.1590211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450508PMC
November 2019
15 Reads

Intermedin protects HUVECs from ischemia reperfusion injury via Wnt/β-catenin signaling pathway.

Ren Fail 2019 Nov;41(1):159-166

b Department of Nephrology , The Affiliated People's Hospital of Shanxi Medical University, Shanxi Provincial People's Hospital, Shanxi Kidney Disease Institute , Taiyuan , China.

Intermedin (IMD) is a member of the calcitonin gene-related peptide (CGRP) superfamily and a pro-angiogenic factor. In the present study, we identified activation of the Wnt/β-catenin signaling pathway by IMD. Adding CoCl HUVECs was used to establish an in vitro model. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1587468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450471PMC
November 2019
2 Reads

Kimura's disease with membranoproliferative glomerulonephritis: a case report with literature review.

Ren Fail 2019 Nov;41(1):126-130

a Department of Nephrology , the First Hospital of Jilin University , Changchun , China.

Background: Kimura's disease is a rare disease and its etiology is still unclear. Here we reported a case with lymphadenopathy complicated with secondary membranoproliferative glomerulonephritis.

Case Presentation: A 46-year-old Chinese man presented with bilateral tumor-like nodules over his neck during the past 6 months and developed edema for 15 days. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1584115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442089PMC
November 2019
1 Read

Kidney injury molecule-1 expression predicts structural damage and outcome in histological acute tubular injury.

Ren Fail 2019 Nov;41(1):80-87

a Department of Nephrology , Zhongshan Hospital, Shanghai Medical College, Fudan University , Shanghai , China.

Background: A few studies have shown that urinary kidney injury molecule-1 (uKIM-1) levels are increased in acute kidney injury (AKI); however, the correlation between uKIM-1 and histological tubular injury, which is considered to be the gold standard for evaluating renal damage and predicting prognosis, is still unclear. We performed this study to determine whether the predicted value of uKIM-1 is correlated with renal KIM-1 (tKIM-1) expression and tissue damage in AKI patients.

Methods: This retrospective study recruited 14 healthy individuals and 27 biopsy-proven acute tubular injury (ATI) patients. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1578234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442099PMC
November 2019
3 Reads

Single dose oral ranolazine pharmacokinetics in patients receiving maintenance hemodialysis.

Ren Fail 2019 Nov;41(1):118-125

g Department of Clinical Pharmacy , University of Michigan College of Pharmacy , Ann Arbor , MI , USA.

Purpose: Ranolazine is a novel anti-angina treatment approved in the United States for chronic stable angina. Ranolazine pharmacokinetics have not been studied previously in patients who receive maintenance hemodialysis. This study describes the pharmacokinetics of ranolazine and three major metabolites (CVT-2738, CVT-2512, CVT-2514) in patients receiving thrice weekly hemodialysis. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1585371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442103PMC
November 2019
1 Read

Hypercalcemia and acute kidney injury induced by eldecalcitol in patients with osteoporosis: a case series of 32 patients at a single facility.

Ren Fail 2019 Nov;41(1):88-97

a Division of Kidney Center , Matsuyama Red Cross Hospital , Matsuyama , Japan.

Background: Eldecalcitol (ELD) is an active vitamin D analog that is widely used in Japan for the treatment of osteoporosis. The most common adverse drug reaction of ELD is hypercalcemia. However, few reports have focused on acute kidney injury (AKI) associated with ELD-induced hypercalcemia. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1578667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442105PMC
November 2019
1 Read

Successful transplantation of kidneys from deceased donors with terminal acute kidney injury.

Ren Fail 2019 Nov;41(1):167-174

a Department of General and Transplantation Surgery , The Medical University of Warsaw , Warsaw , Poland.

Background: There are many doubts with regards to accepting deceased kidneys with acute kidney injury (AKI) for transplantation.

Purpose: The aim of this study was to present the 5-years outcome of kidney transplantation cases where deceased donors developed AKI before organ procurement.

Methods: Two hundred twenty-six deceased renal transplants were analyzed. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1590209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442227PMC
November 2019
1 Read

Carotid intima-media thickness is an independent predictor of all-cause mortality and cardiovascular morbidity in patients with diabetes mellitus type 2 and chronic kidney disease.

Ren Fail 2019 Nov;41(1):131-138

b Department of Vascular Surgery , "Democritus" University of Thrace, Medical School, University General Hospital of Alexandroupolis , Alexandroupolis , Greece.

Background: Intima-Media-Thickness of the carotid artery wall (cIMT) is a strong predictor of cardiovascular (CV) disease. The aim of this study was to investigate the significance of cIMT as an independent prognostic factor for CV morbidity and mortality in patients with chronic kidney disease (CKD) and diabetes mellitus type 2 (DM2).

Methods: The study included 142 diabetic patients in different stages of CKD. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1585372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442115PMC
November 2019

Phosphate supplementation for hypophosphatemia during continuous renal replacement therapy in adults.

Ren Fail 2019 Nov;41(1):72-79

a Dialysis Center , Konkuk University Medical Center , Seoul , Korea.

Background: Hypophosphatemia is common during continuous renal replacement therapy (CRRT) in critically ill patients and can cause generalized muscle weakness, prolonged respiratory failure, and myocardial dysfunction. This study aimed to investigate the efficacy and safety of adding phosphate to the dialysate and replacement solutions to treat hypophosphatemia occurring in intensive CRRT in critically ill patients.

Methods: We retrospectively analyzed 73 patients treated with intensive CRRT (effluent flow ≥35 ml/kg/hr) in the intensive care unit. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1561374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442196PMC
November 2019
1 Read

Robot-assisted radical nephrectomy for primary renal mesenchymal chondrosarcoma: case report and literature review.

Ren Fail 2019 Nov;41(1):98-103

a Department of Urology , The First Affiliated Hospital of Nanchang University , Nanchang , Jiangxi Province , China.

As an extremely rare malignant neoplasm, only 12 mesenchymal chondrosarcoma (MC) arising in kidney have been reported to date. Herein, we reported a case of primary renal MC resected with robot assistance, which has not been reported before. According to the cases reported in English literature, we analyzed the characteristics of this rare malignancy and systematically review its treatment. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1583111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442158PMC
November 2019
1 Read

The value of combined hemodynamic, respiratory and intra-abdominal pressure monitoring in predicting acute kidney injury after major intraabdominal surgeries.

Ren Fail 2019 Nov;41(1):150-158

b Faculty of Health Sciences, Department of Clinical Studies , Semmelweis University , Budapest , Hungary.

Background: The incidence of postoperative acute kidney injury (AKI) is predominantly determined by renal hemodynamics. Beside arterial blood pressure, the role of factors causing a deterioration of venous congestion (intraabdominal pressure, central venous pressure, mechanical ventilation) has emerged. The value of combined hemodynamic, respiratory and intra-abdominal pressure (IAP) monitoring in predicting postoperative acute kidney injury has received only limited exploration to date. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1587467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442204PMC
November 2019
1 Read

Prophylactic laparoscopic omentopexy: a new technique for peritoneal dialysis catheter placement.

Ren Fail 2019 Nov;41(1):113-117

a Department of Nephrology , The First Affiliated Hospital of KangDa College of Nanjing Medical University, The First People's Hospital of Lianyungang , Lianyungang , China.

Background: Prophylactic laparoscopic omentopexy is a safe technique to prevent catheter obstruction during peritoneal dialysis (PD). Here we described a technique through which the omentopexy was accomplished by Hem-o-loks before PD catheter insertion.

Methods: The procedures of omentopexy were described. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1583580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442096PMC
November 2019
0.775 Impact Factor

Hirudin ameliorates immunoglobulin A nephropathy by inhibition of fibrosis and inflammatory response.

Ren Fail 2019 Nov;41(1):104-112

c Department of Traditional Chinese Medicine , Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital , Chengdu , PR China.

Immunoglobulin A nephropathy (IgAN) is characterized by mesangial IgA and IgG co-deposition. As the clinical course of IgAN is highly variable, a lot of patients will eventually develop to end-stage renal disease (ESRD) within years. Hirudin, a potent and specific thrombin inhibitor, has been reported to treat IgAN with hematuria, but the mechanism is unclear. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1583113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427573PMC
November 2019
7 Reads

Renal structural image processing techniques: a systematic review.

Ren Fail 2019 Nov;41(1):57-68

e Department of Electrical Engineering , University of Tabriz , Tabriz , Iran.

Background And Objective: Renal disease, such as nephritis and nephropathy, is very harmful to human health. Accordingly, how to achieve early diagnosis and enhance treatment for kidney disorders would be the important lesion. Nevertheless, the clues from the clinical data, such as biochemistry examination, serological examination, and radiological studies are quite indirect and limited. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2019.1
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http://dx.doi.org/10.1080/0886022X.2019.1572016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374953PMC
November 2019
3 Reads

The incidence, risk factors, and clinical outcomes of acute kidney injury (staged using the RIFLE classification) associated with intravenous acyclovir administration.

Ren Fail 2018 Nov;40(1):687-692

b Department of Internal Medicine , Changwon Gyeongsang National University Hospital , Changwon , South Korea.

Intravenous (IV) acyclovir is commonly administered medication for viral infection but is well known for its nephrotoxicity. However, there was no study for incidence, risk factors, and clinical outcomes of acute kidney injury (AKI) associated with IV acyclovir administration. We retrospectively reviewed the medical records of 287 patients who were medicated IV acyclovir from January 2008 to May 2013 in Gyeongsang National University Hospital. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1487866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319461PMC
November 2018
15 Reads

The anti-inflammatory effects of curcumin on renal ischemia-reperfusion injury in rats.

Ren Fail 2018 Nov;40(1):680-686

c General Medicine Center and University of Electronic Science and Technology , Sichuan Academy of Sciences & Sichuan Provincial People's Hospital , Chengdu , China.

The present study aimed to explore the protective mechanism of curcumin-precondition in renal ischemia-reperfusion (I/R) injury. Thirty male SD rats were randomly equally divided into Sham, IRI, and Curcumin groups (n = 10). The model of IRI was induced by clamping the left renal artery for 45 min followed by 24 h reperfusion with the contralateral nephrectomy. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
Publisher Site
http://dx.doi.org/10.1080/0886022X.2018.1544565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282432PMC
November 2018
7 Reads
0.775 Impact Factor

Hemoglobin targets for the anemia in patients with dialysis-dependent chronic kidney disease: a meta-analysis of randomized, controlled trials.

Ren Fail 2018 Nov;40(1):671-679

a Department of Nephrology , The Third Affiliated Hospital of Sun Yat-sen University , Guangzhou , China.

Background: Anemia is extremely common among dialysis patients and underlies some of the symptoms associated with reduced kidney function, including fatigue, depression, reduced exercise tolerance, and dyspnea.

Objectives: A clearer cognition of the prognosistic impact of hemoglobin (Hb) or hematocrit (Hct) target for the outcomes of dialysis patients is urgent. This article aims to establish the suitable hemoglobin in order to provide clinical guidance. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1532909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282462PMC
November 2018
1 Read

Effect of atorvastatin on iron metabolism regulation in patients with chronic kidney disease - a randomized double blind crossover study.

Ren Fail 2018 Nov;40(1):700-709

a Department of Nephrology, Hypertension and Kidney Transplantation , Medical University of Lodz, University Hospital and Teaching Center , Lodz , Poland.

Introduction: To determine the effect of 6-month administration of atorvastatin on hepcidin and hemojuvelin levels, inflammatory parameters and iron metabolism in patients with chronic kidney disease (CKD) stages 3 and 4.

Methods: Thirty six statin- and erythropoiesis-stimulating agent-naive patients with CKD stages 3 and 4 and LDL cholesterol ≥100 mg/dl received atorvastatin or placebo for two 6-month periods in a double blind, randomized crossover study. Hepcidin, hemojuvelin, hsCRP, IL-6, hemoglobin, red blood cell distribution width, iron, total iron binding capacity (TIBC), and unsaturated iron binding capacity (UIBC) were measured before and after each treatment period. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1535983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319462PMC
November 2018
2 Reads

The logistic organ dysfunction system score predicts the prognosis of patients with alcoholic ketoacidosis.

Ren Fail 2018 Nov;40(1):693-699

b Department of Internal Medicine , Changwon Gyeongsang National University Hospital , Changwon , South Korea.

Alcoholic ketoacidosis (AKA) is occasionally associated with multiple complications leading to death. However, no study has yet evaluated prognostic factors in patients with AKA. It is known that the logistic organ dysfunction system (LODS) score is an objective and useful index to predict the prognosis. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1491405DOI Listing
November 2018
5 Reads

Review of the efficacy of AST-120 (KREMEZIN) on renal function in chronic kidney disease patients.

Ren Fail 2019 Nov;41(1):47-56

a Kureha Corporation , Tokyo , Japan.

AST-120 (KREMEZIN®) consists of oral, spherical carbon particles that adsorb uremic toxins and their precursors within the gastrointestinal tract, allowing them to be excreted in the feces. Uremic toxins such as indoxyl sulfate and p-cresyl sulfate are abundant in the blood of chronic kidney disease (CKD) patients and are related to the progression of both CKD and cardiovascular disease. AST-120 was approved in Japan in 1991 followed by Korea (2004), Taiwan (2007) and the Philippines (2010) for treating uremic symptoms and prolonging the time to initiation of dialysis in patients with progressive CKD. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374968PMC
November 2019
8 Reads

The cartonectin levels at different stages of chronic kidney disease and related factors.

Ren Fail 2019 Nov;41(1):42-46

b Erzurum Regional Research and Training Hospital , Erzurum , Turkey.

Introduction: Cartonectin was defined as a new adipokine released from rat and human adipocyte tissues, which is also known as CORS 26 or CTRP3 protein. Although there are several studies investigating the effects of cartonectin with obesity, anti-inflammatory mechanisms, and cardioprotective effects, there is no study about the effects of cartonectin in patients with chronic kidney disease yet. We aimed to investigate cartonectin levels in predialysis and dialysis patient groups, in other words, at different stages of chronic kidney disease, by comparing with the control group. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1561373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374918PMC
November 2019
0.775 Impact Factor

Association of sirtuin 1 gene polymorphisms with nephrolithiasis in Eastern chinese population.

Ren Fail 2019 Nov;41(1):34-41

a Department of Nephrology , Shanghai Changhai Hospital , Shanghai , China.

Sirtuin 1 (SIRT1), an NAD-dependent deacylase, has been identified to be associated with renal tubular inflammatory conditions and metabolic disorders, which are risk factors of nephrolithiasis. To further confirm the role of the SIRT1 in kidney stone formation, the expression of SIRT1 was analyzed based on a mouse model and the genetic polymorphisms of SIRT1 gene was compared between patients with kidney stones and controls. The calcium oxalate (CaOx) crystal-induced renal injury model was established to analyzed the expression of SIRT1 in the kidney tissue of both wild-type and ApoE(-/-) mice. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1568258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366414PMC
November 2019
1 Read

The aqueous extract of aged black garlic ameliorates colistin-induced acute kidney injury in rats.

Ren Fail 2019 Nov;41(1):24-33

a Department of Internal Medicine , Gyeongsang National University Changwon Hospital , Changwon , Republic of Korea.

The use of colistin in the treatment of multidrug-resistant Gram-negative bacterial infections is restricted due to nephrotoxicity. We investigated the effects of aged black garlic extract (ABGE) on colistin-induced kidney injury in rats. Rats were assigned to four groups. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1561375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366426PMC
November 2019
6 Reads

Effects of prophylactic antibiotics before peritoneal dialysis catheter implantation on the clinical outcomes of peritoneal dialysis patients.

Ren Fail 2019 Nov;41(1):16-23

a Department of Nephrology , Shandong University Qilu Hospital , Jinan , China.

Background: Peritoneal dialysis (PD) related infections, such as peritonitis, are still the main obstacle for the development of PD. Prophylactic antibiotic as one of the interventions to prevent early peritonitis was recommended to use before PD catheter insertion by International Society for Peritoneal Dialysis (ISPD) guidelines, In our hospital, however, since 2012, the prophylactic antibiotics for insertion of PD catheters were not allowed to use because of our hospital's regulation. In order to analyze the outcomes of PD patients without using prophylactic antibiotics before the PD catheter insertion, we compared the PD patients with or without prophylactic antibiotics before PD catheter insertion. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2019.1
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http://dx.doi.org/10.1080/0886022X.2019.1568259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366413PMC
November 2019
14 Reads

Risk factors analysis for hyperuricemic nephropathy among CKD stages 3-4 patients: an epidemiological study of hyperuricemia in CKD stages 3-4 patients in Ningbo, China.

Ren Fail 2018 Nov;40(1):666-671

a Beilun People's Hospital & the Beilun Branch of the First Affiliated Hospital of School of Medicine , Zhejiang University , Ningbo , Zhejiang , China.

Objective: Uric acid (UA) is a risk marker of CKD and SUA level in CKD 3-4 patients closely correlates with hyperuricemic nephropathy (HN) morbidity. This study was designed to evaluate the risk factors for HN in CKD 3-4 patients.

Methods: The 461 CKD 3-4 patients were recruited and all patients were divided into three groups (24 h UUA normal, underexeret, and overproduct type groups) according to the 24 h UUA level after receiving low purine food for five days. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1487859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282434PMC
November 2018
20 Reads

Changes in the diagnosis of glomerular diseases in east China: a 15-year renal biopsy study.

Ren Fail 2018 Nov;40(1):657-664

a Kidney Disease Centre, The First Affiliated Hospital , Zhejiang University School of Medicine , Hangzhou , China.

Background: There have been some gradual changes in the distribution of renal biopsy pathological diagnoses during recent years. This study aimed to show changes in renal disease prevalence in China by investigating 10 patients diagnosed at our Kidney Disease Centre during the last 15 years.

Methods And Results: All patients aged 15-year-old or older who underwent renal biopsy at the First Affiliated Hospital, Zhejiang University, from 2001 to 2015 were enrolled. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1537930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282433PMC
November 2018
7 Reads
0.775 Impact Factor

Inhibitors of the renin-angiotensin system ameliorates clinical and pathological aspects of experimentally induced nephrotoxic serum nephritis.

Ren Fail 2018 Nov;40(1):640-648

a Haemophilia PK & ADME , Novo Nordisk , Frederiksberg , Denmark.

Introduction: Chronic kidney disease (CKD) is a global health concern, but the current treatments only slow down the progression. Thus an improved understanding of the pathogenesis and novel treatments of CKD are needed. The nephrotoxic nephritis (NTN) model has the potential to study the pathogenesis of CKD as it resembles human CKD. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1533867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225365PMC
November 2018
16 Reads

Significance of M2 macrophage in tubulointerstitial disease secondary to primary Sjogren's disease.

Ren Fail 2018 Nov;40(1):634-639

c Department of Nephrology , Clinical Medical College, Yangzhou University , Yangzhou , China.

Objective: M2 Macrophages could improve tubulointerstitial disease in animal models. HIF-1αpromotes macrophage polarization and is involved in tubular injury. The study aims to observe the clinicopathologic significance of M2 macrophage and HIF-1α in tubulointerstitial injury secondary to primary Sjogren's disease. Read More

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http://dx.doi.org/10.1080/0886022X.2018.1518242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225512PMC
November 2018
20 Reads
0.775 Impact Factor

Protective potential of Angelica sinensis polysaccharide extract against ethylene glycol-induced calcium oxalate urolithiasis.

Ren Fail 2018 Nov;40(1):618-627

a The Emergency Center, Gansu Nephro-Urological Clinical Center, Lanzhou University Second Hospital , Lanzhou China.

Purpose: To evaluate a Angelica sinensis polysaccharide aqueous extract as a preventive agent in experimentally induced urolithiasis using in- vitro and vivo models.

Material And Methods: Angelica sinensis polysaccharide was investigated in vitro to determine its antilithiatic effects on the formation and morphology of calcium oxalate (CaOx) crystals and was analyzed in vivo to determine its ability to prevent CaOx urolithiasis in rats subjected to ethylene glycol-induced urolithiasis. Potassium citrate administration was used in the positive control group. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1496935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225371PMC
November 2018
17 Reads

Vegetarian diet may ameliorate uremic pruritus in hemodialysis patients.

Ren Fail 2018 Nov;40(1):514-519

g Division of Nephrology , Asia University Hospital , Taichung , Taiwan.

Objectives: Systemic inflammation has been reported to be associated with uremic pruritus (UP). Although a vegetarian diet can reduce systemic inflammation in hemodialysis patients, the effect of vegetarian diet on UP is not clear. The purpose of the study was to know the possible effects of vegetarian diet on UP. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1512871DOI Listing
November 2018
20 Reads

Impact of acute kidney injury in donors on renal graft survival: a systematic review and Meta-Analysis.

Ren Fail 2018 Nov;40(1):649-656

a Organ Transplant Center, The First Affiliated Hospital , Sun Yat-sen University , Guangzhou , Guangdong , China.

The acute kidney injury (AKI) of deceased donors was an important strategy to address donor shortage. This meta-analysis was conducted to explore the clinical effect of kidney transplantation from donors with AKI. PubMed, Embase, and Cochrane Library were searched through July 2017. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
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http://dx.doi.org/10.1080/0886022X.2018.1535982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225519PMC
November 2018
16 Reads

Reducing the occurrence rate of catheter dysfunction in peritoneal dialysis: a single-center experience about CQI.

Ren Fail 2018 Nov;40(1):628-633

a Department of Nephrology , The Third Xiangya Hospital of Central South University , Changsha , China.

To reduce the occurrence rate of peritoneal dialysis (PD) catheter dysfunction caused by catheter displacement or plugging, this study screened all patients with peritoneal dialysis catheterization from 2002 to 2015 from the Third Xiangya Hospital of Central South University. There were 256 patients before continuous quality improvement (CQI) (from 2002 to 2007) and 813 patients after CQI (from 2008 to 2015). The occurrence rate of catheter dysfunction was 5. Read More

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https://www.tandfonline.com/doi/full/10.1080/0886022X.2018.1
Publisher Site
http://dx.doi.org/10.1080/0886022X.2018.1515084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225513PMC
November 2018
21 Reads
0.780 Impact Factor