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Scand J Surg 2020 Jun 3:1457496920920474. Epub 2020 Jun 3.

Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.

Objective: To compare the standard percutaneous nephrolithotomy and mini-percutaneous nephrolithotomy in order to determine the optimal tract size for patients with renal stones.

Methods: A systematic search of Web of Science, EMBASE, Cochrane Library, and PubMed databases was conducted for articles published through 20 August 2019, reporting on a comparison of the standard percutaneous nephrolithotomy and mini-percutaneous nephrolithotomy using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

Results: Of 763 studies, 14 were considered for the evidence synthesis. Read More

J Int Med Res 2020 Jun;48(6):300060520926736

Department of Urology, the Fourth Medical Center of PLA General Hospital, Beijing, China.

A horseshoe kidney is a congenital kidney malformation commonly associated with complications such as hydronephrosis, renal calculi, and infections of the renal pelvis. Renal cell carcinoma is extremely rare in a horseshoe kidney; once it occurs, however, it is intractable because of vascular abnormalities. This is especially true in laparoscopic nephron-sparing surgery, even for tumors of <4 cm in diameter. Read More

J Biol Inorg Chem 2020 Jun 2. Epub 2020 Jun 2.

BioCruces Sanitary Research Institute, Cruces University Hospital, Barakaldo, Spain.

The genesis and growth of calculi are imprinted in their structure, so the pathogenesis of lithiasis could potentially be read via proper analytical techniques. In this study, electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDX) is used to obtain a description of the morphology and compositional structure of a single bladder stone. This technique establishes the chemical and crystalline architecture of the urolith to assess the effect of the chemical environment on its growth. Read More

Urol Int 2020 Jun 2:1-6. Epub 2020 Jun 2.

U-merge Ltd., London, United Kingdom.

Objectives: To evaluate Guy's Stone Score (GSS) as a grading system for the complexity of renal calculi before percutaneous nephrolithotomy (PCNL) and as a predictor for stone-free rate (SFR) and potential complications in the setting of a developing country with many cases of advanced complex stone disease.

Patients And Methods: We performed a prospective study on 115 patients with renal stones who had PCNL between August 2017 and October 2018. Stone complexity was classified according to GSS using preoperative imaging. Read More

Sci Rep 2020 Jun 1;10(1):8839. Epub 2020 Jun 1.

Department of Urology, Kidney Stone Center, Tokyo Metropolitan Ohtsuka Hospital, 2-8-1 Minami-Ohtsuka, Toshima-ku, Tokyo, Japan.

Due to the aging population, the number of completely bedridden individuals is expected to increase, and such individuals are at high risk of developing urinary calculi. This retrospective study included 32 consecutive bedridden patients, who had undergone endoscopic lithotripsy between 2010 and 2019, and aimed to identify the treatment outcomes of endoscopic lithotripsy for bedridden patients. A total of 45 endoscopic lithotripsies were performed to treat stones (median cumulative diameter, 24 mm). Read More

J Endourol 2020 May 30. Epub 2020 May 30.

University Medical Center Freiburg, Department of Urology, Hugstetter Straße 55, Freiburg, Germany, 79104;

Objectives: Due to the increasing fragility of the instruments and rising concerns about the sterility of reprocessable scopes, several single-use devices for fURS have been introduced. In this study we compare currently available disposable digital and fiberoptic flexible ureteroscopes with a contemporary reusable fiberoptic device.

Methods: LithoVue™, Pusen Uscope® (UE3011, UE3022), Flexor®Vue™ and a reusable fiber optic flexible ureteroscope (BOA vision®) were tested in kidney models. Read More

Yonsei Med J 2020 Jun;61(6):515-523

Department of Nursing Science, College of Nursing, Gachon University, Incheon, Korea.

Purpose: This study aimed to evaluate the cost-effectiveness of treatment with retrograde intrarenal surgery (RIRS) versus repeated shock wave lithotripsy (SWL) in patients with renal calculi.

Materials And Methods: The non-retreatment rates (NRRs) and their respective real-world costs for RIRS and SWL were derived through retrospective analysis of health insurance claims data from 2015 to 2017. Decision tree modeling was performed to demonstrate the cost-effectiveness of RIRS. Read More

World J Urol 2020 May 26. Epub 2020 May 26.

Department of Urology, Minimally Invasive Surgery Center, Guangdong Key Laboratory of Urology, Guangzhou Institute of Urology, The First Affiliated Hospital of Guangzhou Medical University, 1 Kangda Road, Haizhu District, Guangzhou, 510230, Guangdong, China.

Objective: In the present prospective randomized controlled trial (RCT), enhanced-SMP (eSMP) and conventional Chinese mini-PCNL (mPCNL) were compared to test the low renal pelvic pressure (RPP) and high stone removal efficiency in eSMP.

Materials And Methods: Hundred patients with 2-5 cm renal calculus were enrolled. Renal pelvic pressure, operation time, lithotripsy time, removed stone volume, and complications were compared between eSMP and mPCNL statistically. Read More

World J Urol 2020 May 23. Epub 2020 May 23.

Department of Urology, Guangdong Key Laboratory of Urology, Minimally Invasive Surgery Center, Guangzhou Institute of Urology, The First Affiliated Hospital of Guangzhou Medical University, Haizhu District, Kangda Road 1#, Guangzhou, 510230, Guangdong, China.

Purpose: The purpose of this study was to evaluate the safety and efficiency of multiple-tract percutaneous nephrolithotomy (PCNL) as a day surgery for the treatment of complex renal stones. PATIENTS AND METHODS: A mature protocol for day surgery was implemented. Forty-six patients who underwent planned day-surgery PCNL via multiple tracts for the treatment of complex renal stones were retrospectively reviewed. Read More

Medicina (B Aires) 2020 ;80(3):241-247

Sociedad Argentina de Infectología, Argentina.

The second part of the Inter-Society Argentine Consensus on Urinary Tract Infection (UTI) includes the analysis of special situations. In patients with urinary catheter, urine culture should be requested only in the presence of UTI symptomatology, before instrumentation of the urinary tract, or as a post-transplant control. The antibiotics recommended for empirical treatment in patients without risk factors are third-generation cephalosporins or aminoglycosides. Read More

J Complement Integr Med 2020 May 19. Epub 2020 May 19.

Central Council for Research in Unani Medicine, New Delhi, Ministry of AYUSH, Govt of India, India.

Background Hasat-ul Kilya (Nephrolithiasis) is one of the most common chronic conditions and has been known to the mankind since antiquity. The incidence is increasing globally with geographic, racial and gender variation in its occurrence. Medical management of Nephrolithiasis still poses a considerable challenge for modern medical practice. Read More

Clin Pract Cases Emerg Med 2020 May 24;4(2):134-136. Epub 2020 Feb 24.

University of Las Vegas, Department Emergency Medicine, Las Vegas, Nevada.

Urolithiasis is a condition with calculi commonly found within the kidney, ureter, or bladder. The urethra is an uncommon location of urolithiasis, with limited case reports and literature reviews of its presentation and management. Here we discuss a 24-year-old female who presented with urinary urgency, flank pain, and urinary retention for 12 hours. Read More

Adv Urol 2020 29;2020:4347598. Epub 2020 Jan 29.

Department of Urology and Kidney Transplant Surgery, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgung, Kathmandu 44600, Nepal.

Introduction: Urolithiasis is one of the common disorder with which about 1/5 is found in the ureter, of which 2/3 is seen in the lower ureter. Medical expulsive therapy is one of the routine modalities of treatment which uses various drugs acting on the ureter smooth muscle by different mechanism. We aim to compare the efficacy of combination vs. Read More

J Invest Surg 2020 May 13:1-5. Epub 2020 May 13.

Urology and Lithotripsy Center, Peking University People's Hospital, Beijing, China.

To evaluate the outcome of ultrasound (US)-guided minimally invasive percutaneous nephrolithotomy (MPCNL) in the management of upper ureteral and renal stones in pediatric patients. We collected data of 112 pediatric patients who were admitted to the xxxx between March 2006 and December 2016 and treated by US-guided MPCNL. Our cohort included upper ureter stones ( = 11), single kidney stones ( = 46), multiple kidney stones ( = 56), and staghorn kidney stones ( = 12). Read More

Cent European J Urol 2020 3;73(1):49-54. Epub 2020 Jan 3.

Department of Urology, Kafkas University Faculty of Medicine, Kars, Turkey.

Introduction: The aim of this article was to evaluate the safety and efficiency of flexible ureteroscopy (fURS) in the management of renal calculi larger than 20 mm.

Material And Methods: A total of 92 cases with renal calculi were managed with fURS and divided into two groups depending on the size of the stones; <20 mm and >20 mm (Group 1 and Group 2, respectively). The groups were compared with respect to treatment-related parameters including success, complication rates, hospitalization period and need for auxiliary procedures with an emphasis on the rate of infections. Read More

Front Pediatr 2020 22;8:200. Epub 2020 Apr 22.

Department of Pediatric Urology, Xinhua Hospital, Shanghai Jiao Tong University of Medicine, Shanghai, China.

To evaluate our use of external ureteral catheters in children with acute kidney injury (AKI) resulting from ceftriaxone-induced urolithiasis. From July 2010 to June 2015, a series of 15 children, including 12 males and 3 females, were referred to our department. All of them were diagnosed of post-renal AKI and underwent emergent hospitalization. Read More

Clin Exp Nephrol 2020 May 8. Epub 2020 May 8.

Department of Urology, the First Affiliated Hospital of Anhui Medical University, Jixi Road #218, Hefei, Anhui, 230022, P.R. China.

Objectives: Patients with autosomal dominant polycystic kidney disease (ADPKD) showed relatively high incidence of urinary stones. Enlarged kidneys occupied by cysts could make the stone-removal surgery relatively difficult. This study aimed to compare the efficacy and safety of retroperitoneal laparoscopic ureterolithotomy (RPLU), flexible ureteroscopic lithotripsy (FURL) and percutaneous nephrolithotomy (PCNL) in the ADPKD patients with upper urinary stones. Read More

Medicine (Baltimore) 2020 May;99(19):e19915

Department of Urology, Yangling Demonstration District Hospital, Xianyang, China.

Background: This study will assess the effectiveness and safety of extracorporeal shock wave lithotripsy (ESWL) for patients with kidney stones (KS).

Methods: A comprehensive and systematic literature records search for studies will be conducted in MEDLINE, EMBASE, Cochrane Library, WANGFANG, VIP, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure. All these databases will be searched from inception to the present without language limitation. Read More

Urolithiasis 2020 May 5. Epub 2020 May 5.

Department of Urology, Changhai Hospital, Second Military Medical University, 168 Changhai Rd, Shanghai, 200433, China.

The study aims to identify whether gender differences exist in the sequential organ failure assessment (SOFA) score to the extent of affecting its predictive accuracy for septic shock after percutaneous nephrolithotomy (PCNL). A retrospective study of 612 patients undergoing PCNL was performed. The SOFA scores of male and female groups were compared to identify any gender differences. Read More

Urolithiasis 2020 May 5. Epub 2020 May 5.

School of Medicine, Universidad Nacional Autónoma de México, Av. Universidad 3000, C.U., Coyoacán, 04510, Mexico City, Mexico.

The Spanish version of the Wisconsin Stone Quality of Life (WISQOL) questionnaire was developed and validated. A double-back translation of the WISQOL was conducted and syntactic amendments were made, resulting in the Spanish version of the WISQOL (S-WISQOL) which then went through a readability analysis. Stone formers from two hospitals in Mexico (Merida and Monterrey) filled in the S-WISQOL and the Short Form 36 (SF36). Read More

Urol Case Rep 2020 Sep 23;32:101224. Epub 2020 Apr 23.

Department of Urology and Surgery, Superspeciality Hospital, Govt. Medical College Hospital, Jammu, 180001, India.

Pyeloduodenal fistula is a rare entity, with very few cases reported in the world literature so far. Commonly found in three disease entities - chronic renal inflammatory disease secondary to renal calculi, renal tuberculosis and renal malignancies in order of frequency; this disease entity is a rare to diagnose and treat. Read More

J Int Med Res 2020 May;48(5):300060520911252

Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, China.

Objective: This study aimed to present our experience of concomitant management of renal calculi and recurrent ureteropelvic junction obstruction (UPJO) with percutaneous nephrolithotomy (PCNL) and antegrade balloon dilation.

Methods: We retrospectively reviewed 31 patients who underwent PCNL and antegrade balloon dilation for treatment of renal calculi and recurrent UPJO. The inclusion criterion was the presence of UPJO after failed pyeloplasty with ipsilateral renal calculi. Read More

J Int Med Res 2020 Apr;48(4):300060520921667

Department of Urology, Second People's Hospital of Yichang, Second People's Hospital of China Three Gorges University, Yichang, Hubei, China.

Certain drugs can cause kidney stones but as far as we are aware, ceftazidime-related urinary calculi have not been previously reported. We report here a case of an 8-year-old boy who developed hydronephrosis secondary to urinary calculi after receiving ceftazidime 2.0 g by intravenous infusion daily for two weeks. Read More

World J Urol 2020 Apr 28. Epub 2020 Apr 28.

Department of Urology, Biruni University, Istanbul, Turkey.

Aims: To outline and evaluate the incidence, management and follow-up of the residual fragments (RFs) following retrograde intrarenal surgery (RIRS) of renal stones by the Turkish Academy of Urology Prospective Study Group (ACUP Study).

Methods: Following the ethical committee approval, 15 centers providing data regarding the incidence, management, and follow-up of RFs after RIRS were included and all relevant information was recorded into the same electronic database program (https://acup.uroturk. Read More

Acta Med Okayama 2020 Apr;74(2):175-178

Department of Urology, Zhujiang Hospital, Southern Medical University.

Urolithiasis, a common condition in patients with spinal deformity, poses a challenge to surgical procedures and anesthetic management. A 51-year-old Chinese male presented with bilateral complex renal calculi. He was also affected by severe kyphosis deformity and spinal stiffness due to ankylosing spondylitis. Read More

JNMA J Nepal Med Assoc 2019 Nov-Dec;57(220):444-448

Department of Urology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.

Introduction: Renal stone disease has been affecting people for centuries. Percutaneous nephrolithotomy is one of the five interventions offered to a patient with renal stone. With the continuous development of noninvasive or minimally invasive techniques, these surgical procedures have been refined over time. Read More

BMC Urol 2020 Apr 25;20(1):46. Epub 2020 Apr 25.

Hospital Universitari Son Espases, Ctra. Valldemossa, 79, Palma de Mallorca, Spain.

Background: Our purpose was to study the relationship of the 3 different types of endoscopic calcifications of the renal papilla (Randall's plaque, intratubular calcification, papillary crater) with the type of stone and urine analysis.

Methods: This prospective study examined 41 patients (age range: 18 to 80 years) who received retrograde intrarenal surgery (RIRS) for renal lithiasis (mean stone size: 15.3 ± 7. Read More

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2020 Apr;37(2):230-235

Andrology Laboratory, Department of Urology, West China Hospital, Sichuan University, Chengdu 610041, P.R.China.

Recently, artificial intelligence (AI) has been widely applied in the diagnosis and treatment of urinary diseases with the development of data storage, image processing, pattern recognition and machine learning technologies. Based on the massive biomedical big data of imaging and histopathology, many urinary system diseases (such as urinary tumor, urological calculi, urinary infection, voiding dysfunction and erectile dysfunction) will be diagnosed more accurately and will be treated more individualizedly. However, most of the current AI diagnosis and treatment are in the pre-clinical research stage, and there are still some difficulties in the wide application of AI. Read More

Urol Case Rep 2020 Sep 14;32:101209. Epub 2020 Apr 14.

Division of Clinical Microbiology, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

is one of more than 50 different species belonging to the genus . This bacterium is rarely reported to cause human infections. Here we described a rare case of , which grew in urine culture approximately one month after the patient was discharged from the hospital with antibiotics for a urinary tract infection, which caused left obstructing renal calculi requiring nephrostomy tube placement. Read More

Urol Case Rep 2020 Sep 8;32:101195. Epub 2020 Apr 8.

Department of Urology, Aleppo University Hospital, Aleppo, Syria.

Double-j ureteral stents have been widely used as part of urologic practice. The main use is to provide urinary drainage from the kidney to the bladder. With the increase use, several complications are seen related to stents. Read More

J Endourol 2020 Apr 22. Epub 2020 Apr 22.

University Hospitals Southampton NHS Trust, Urology, Southampton, United Kingdom of Great Britain and Northern Ireland.

Introduction: Paediatric upper urinary tract calculi can be treated by Ureteroscopy (URS) or Mini-percutaneous nephrolithotomy (mPCNL). We wanted to compare outcomes of URS and mPCNL from two tertiary referral centres who specialised in one of these treatments for paediatric stone disease.

Methods: Data was collected from two tertiary centres over a 10-year period (2010-2019); one centre specialising in URS and the other in mPCNL for consecutive patients ≤16 years of age undergoing either of these minimally invasive interventions. Read More

Urol J 2020 May 16;17(3):232-236. Epub 2020 May 16.

Department of Urology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Purpose: The goal of this study is to compare the feasibility, safety, and efficacy of the preemptive indwelling of double-J stents (PI-DJS) versus the conventional preemptive indwelling of ureteral catheters (PI-UC) in percutaneous nephrolithotomy (PCNL) via a randomized, controlled clinical study.

Materials And Methods: A total of 75 patients with complex renal calculi underwent PCNL surgery and were randomized, using random number table, to receive either a PI-DJS (37 cases) or a PI-UC (38 cases). All operations were performed by the same experienced surgeon. Read More

Urol J 2020 04 19. Epub 2020 Apr 19.

Department of Urology, the 3rd Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Purpose: This study aimed to investigate the efficacy and safety of febuxostat in patients with radiolucent nephrolithiasis.

Materials And Methods: From March 2016 to June 2018, data of 96 patients with radiolucent nephrolithiasis and hyperuricemia who referred to the Third Affiliated Hospital of Sun Yat-sen University were retrospectively analyzed. These patients were divided into allopurinol 300mg/d (control), febuxostat 40mg/d (F40) and 80mg/d (F80) groups respectively. Read More

Urol J 2020 Apr 13. Epub 2020 Apr 13.

Xiangya International Medical Center, Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, P. R. China, 410008.

Purpose: To investigate the safety and efficacy of Single Percutaneous Tract Combined with Flexible Nephroscopy in the Management of 2-4 cm renal calculi.

Materials And Methods: We retrospectively analysed the treatment data of patients with 2-4 cm renal calculi from June 2010 to June 2017. The data included 217 cases of percutaneous nephrolithotomy (PNL), 441 cases of retrograde intrarenal surgery (RIRS) and 217 cases of single-access percutaneous nephrolithotomy combined with flexible nephroscopy (PNCFN). Read More

BJU Int 2020 Apr 11. Epub 2020 Apr 11.

Department of Urology, Guangdong Key Laboratory of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Objectives: To comparatively evaluate the clinical outcomes of super-mini percutaneous nephrolithotomy (SMP) and mini-percutaneous nephrolithotomy (Miniperc) for treating urinary tract calculi of >2 cm.

Patients And Methods: An international multicentre, retrospective cohort study was conducted at 20 tertiary care hospitals across five countries (China, the Philippines, Qatar, UK, and Kuwait) between April 2016 and May 2019. SMP and Miniperc were performed in 3525 patients with renal calculi with diameters of >2 cm. Read More

Arch Acad Emerg Med 2020 18;8(1):e27. Epub 2020 Mar 18.

Department of Emergency Medicine, State University of New York (SUNY) Downstate Medical Center, Brooklyn, NY, USA.

Introduction: Renal colic affects 12% of the U.S. population, accounting for nearly 1% of emergency department (ED) visits. Read More

Asian J Urol 2020 Apr 19;7(2):139-148. Epub 2019 Oct 19.

Department of Urology, University of California, Oakland, CA, USA.

Staghorn calculi comprise a unique subset of complex kidney stone disease. Percutaneous nephrolithotomy (PCNL) is the gold standard treatment for staghorn stones. Despite continuous refinements to the technique and instrumentation of PCNL, these stones remain a troublesome challenge for endourologists and are associated with a higher rate of perioperative complications than that for non-staghorn stones. Read More

Asian J Urol 2020 Apr 17;7(2):122-129. Epub 2019 Dec 17.

Duke Comprehensive Kidney Stone Center, Division of Urologic Surgery, Duke University Medical Center, Durham, NC, USA.

Staghorn renal calculi are large renal calculi that occupy nearly the entirety of the renal collecting system. They may be composed of metabolic or infection stone types. They are often associated with specific metabolic defects. Read More

Asian J Urol 2020 Apr 28;7(2):102-109. Epub 2019 Dec 28.

Department of Urology, Muljhibhai Patel Urological Hospital, Nadiad, Gujarat, India.

Complex renal calculi remain to be a challenge for the treating urologist due to sheer bulk and the technicalities involved. Percutaneous nephrolithotomy (PCNL) remains the treatment modality of choice in dealing with these large and complex stones. The limiting factor in their treatment continues to be the need for using additional tracts or the use of flexible nephroscopy for complete stone clearance. Read More

Asian J Urol 2020 Apr 8;7(2):94-101. Epub 2019 Oct 8.

Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, India.

Staghorn calculi are branched stones which occupy a majority portion of the pelvicaliceal system. An untreated staghorn calculus over time can damage the kidney and deteriorate its function and/or cause life threatening sepsis. Total stone clearance is an important goal in order to eradicate any infective focus, relieve obstruction, prevent recurrence and preserve the kidney function. Read More

Asian J Urol 2020 Apr 6;7(2):87-93. Epub 2019 Jul 6.

Department of Urology, Wake Forest University Baptist Medical Center, Winston-Salem, NC, USA.

Objective: Staghorn calculi present a particular and challenging entity of stone morphology. Treatment is associated with lower stone-free rates and higher complication rates compared to non-staghorn stones. In this review we looked for the most relevant data on preoperative imaging and access planning to help decision making for percutaneous surgery with this complex condition. Read More

Asian J Urol 2020 Apr 12;7(2):78-86. Epub 2019 Jun 12.

Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Due to their large size, rapid growth, and attendant morbidity, staghorn calculi are complex clinical entities that impose significant treatment-related challenges. Moreover, their relative heterogeneity-in terms of both total stone burden and anatomic distribution-limits the ability to standardize their characterization and the reporting of surgical outcomes. Several morphometry systems currently exist to define the volumetric distribution of renal stones, in general, and to predict the outcomes of percutaneous nephrolithotomy; however, they fall short in their applicability to staghorn stones. Read More

J Pediatr Urol 2020 Mar 19. Epub 2020 Mar 19.

Royal Manchester Children's Hospital, Manchester, UK.

Background: The epidemiology and risk factors for paediatric urolithiasis (UL) in developed countries are evolving, with increasing rates of metabolic stone-formers. In the United Kingdom (UK), only a single London cohort has been studied in the past three decades. Regional disease patterns across the UK remain unknown. Read More

Eur Radiol 2020 Apr 3. Epub 2020 Apr 3.

Diagnosezentrum Favoriten, Radiology Center, Am Hauptbahnhof 2/4, 1100, Vienna, Austria.

Objectives: Previous studies have shown that split-bolus protocols in virtual non-contrast (VNC) reconstructions of dual-energy computed tomography (DE-CT) significantly decrease radiation dose in patients with urinary stone disease. To evaluate the impact on kidney stone detection rate of stone composition, size, tube voltage, and iodine concentration for VNC reconstructions of DE-CT.

Methods: In this prospective study, 16 kidney stones of different sizes (1. Read More

Med Sci Monit 2020 Apr 3;26:e919360. Epub 2020 Apr 3.

Department of Pharmacy, Chongqing Three Gorges Central Hospital, Chongqing, China (mainland).

BACKGROUND This study aimed to undertake a network pharmacology analysis to identify the active compounds of the herbal extract Christina Loosestrife, or Lysimachia Christinae (Jin Qian Cao), in the treatment of nephrolithiasis. MATERIAL AND METHODS The active components of Christina Loosestrife were identified from the Traditional Chinese Medicine Systems Pharmacology (TCMSP) database and analysis platform and the online Taiwan TCM database. The potentially active compounds were screened based on their parenteral bioavailability identified from the TCMSP database. Read More

Medicine (Baltimore) 2020 Mar;99(13):e19611

The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi.

Introduction: Kidney stone is caused by abnormal accumulation of crystalline substances in the kidneys. Kidney stone is one of the urinary system diseases with a high incidence. In this study, we will use the research method of randomized controlled trials to explore the effects of Traditional Chinese medicine combined with western medicine on renal function and urine metabolism in women with kidney stones. Read More

Int Braz J Urol 2020 Mar 15;46. Epub 2020 Mar 15.

Stevan B, Streem Center for Endourology & Stone Disease, Glickman Urological & Kidney Institute, The Cleveland Clinic, Cleveland, OH, USA.

Patients with staghorn renal stones are challenging cases, requiring careful preoperative evaluation and close follow-up to avoid stone recurrence. In this article we aim to discuss the main topics related to staghorn renal stones with focus on surgical approach. Most of staghorn renal stones are composed of struvite (magnesium ammonium phosphate) and are linked to urinary tract infection by urease-producing pathogens. Read More

Radiol Case Rep 2020 May 18;15(5):564-569. Epub 2020 Mar 18.

Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.

Duplication of ureter is one of the most common anomalies of the urinary tract. Early detection has dramatically increased due to advance in technology of imaging to detect the anomalies during antenatal period; however, numbers of undiagnosed adult still exist. It may remain asymptomatic, but may cause repeated urinary tract infections or calculi. Read More

Iran J Med Sci 2020 Mar;45(2):134-139

Department of Pharmacognosy, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.

Background: Kidney stone disease can be quite painful, recurrent, and affects many people. Despite advances in drug therapy, there is still a need to find effective drugs with fewer complications for long-term treatment of kidney stones and to prevent its recurrence. The present study aimed to evaluate the effect of L. Read More

Br J Radiol 2020 Jun 25;93(1110):20190771. Epub 2020 Mar 25.

Heartlands, Good Hope, and Solihull Hospitals, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.

Objectives: Computed tomography scans of the kidney, ureters, and bladder (CT-KUB) are crucial in investigating urinary calculi but impart a substantial radiation doses. Radiation can be limited by minimising the scanning field to the necessary area ( from the kidneys to urethra). Before auditing, the superior limit of CT-KUB scans had not been formally clarified at our trust. Read More