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Sci Rep 2022 May 19;12(1):8366. Epub 2022 May 19.

School of Clinical Medicine, Tsinghua University, Beijing, China.

Percutaneous nephrolithotomy (PCNL) is a minimally invasive procedure for removing renal calculi, while a large number of patients experience acute moderate-to-severe pain despite the analgesia provided. This study aimed to explore the risk factors for postoperative pain after PCNL, which may provide a novel perspective to refine the enhanced recovery after surgery (ERAS) program and to improve clinical outcomes. The clinical data of 331 patients who underwent PCNL in our hospital from September 2020 to February 2021 were retrospectively analyzed. Read More

Braz J Biol 2022 27;84:e259100. Epub 2022 Apr 27.

King Faisal University, College of Sciences, Department of Biological Sciences, Al-Ahsa, Saudi Arabia.

The potential of Alhagi maurorum (Boiss.) aqueous extract (AME), used in traditional medicine for treatment or prevention of urolithiasis, to dissolve calcium oxalate stones in vitro was evaluated. In order to determine the litholytic potential of the extract, Calcium oxalate urinary stones were incubated during 12 weeks under continuous shaking in the presence of AME, Rowanix or NaCl 9 g/mL solution were used as controls. Read More

Eur Rev Med Pharmacol Sci 2022 May;26(9):3185-3191

Department of Urology, the Affiliated Southeast Hospital of Xiamen University, Zhangzhou, Fujian, China.

Objective: To investigate the safety and efficacy of visualized ultra-mini percutaneous nephrolithotripsy (VUMP) and flexible ureterorenoscopy (FURS) in the treatment of nephrolithiasis patients with 1.5-2.5 cm kidney stones and without hydronephrosis. Read More

Front Endocrinol (Lausanne) 2022 2;13:863675. Epub 2022 May 2.

Department of Urology, Xiangya Hospital, Central South University, Changsha, China.

Background: The role of serum testosterone levels in male renal stone formation remains controversial. This study aimed to evaluate the relationship between serum testosterone levels and kidney stone prevalence in males.

Methods: We conducted a cross-sectional study based on the data from the National Health and Nutrition Examination Survey 2011-2016, which included 6,633 male participants, to investigate the association between testosterone levels and the prevalence of kidney stones. Read More

Front Surg 2022 29;9:878660. Epub 2022 Apr 29.

Department of Urology, The Affiliated Zhuzhou Hospital of Xiangya Medical College, Central South University, Zhuzhou, China.

Ureteral stents are widely used. If ureteral stents remain in place for extended periods, the probability of migration and stone formation increases substantially. However, a 29-year-old ureteral stent that was placed and did not develop calculus is rare. Read More

Nutrients 2022 Apr 27;14(9). Epub 2022 Apr 27.

Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, 100, Shih-Chuan 1st Road, Kaohsiung 80708, Taiwan.

There is a great need for a diagnostic tool using simple clinical information collected from patients to diagnose uric acid (UA) stones in nephrolithiasis. We built a predictive model making use of machine learning (ML) methodologies entering simple parameters easily obtained at the initial clinical visit. Socio-demographic, health, and clinical data from two cohorts (A and B), both diagnosed with nephrolithiasis, one between 2012 and 2016 and the other between June and December 2020, were collected before nephrolithiasis treatment. Read More

Br J Nurs 2022 May;31(9):S14-S22

Senior Lecturer, Department of Health, Psychology and Social Care, University of Derby.

This clinical review on renal and ureteric stones discusses how stones form, the incidence, risks, and complications associated with calculi. It reflects on the management and treatment options available, and highlights the important contribution by nurses and those working in advanced clinical practice roles in using their knowledge and rational clinical decision making to ensure timely recognition, prompt investigation, management and ongoing health promotion. Read More

Environ Sci Pollut Res Int 2022 May 13. Epub 2022 May 13.

Cleveland Clinic - Glickman Urologic and Kidney Institute, Cleveland, OH, USA.

In the process of urinary stone formation, several heavy metals and trace elements (HMTE) have been identified among the major constituents of the calculi. The micro-elements within the stones cannot be identified by ordinary laboratory analytical techniques, the latter can only detect the major crystalline component. The objective of the present study was to evaluate the different types of HMTE (no. Read More

BMC Nephrol 2022 May 12;23(1):182. Epub 2022 May 12.

Nephrology Department, Heraklion University Hospital, Voutes, 71500, Heraklion, Crete, Greece.

Background: Dent disease is an X-linked disorder characterized by low molecular weight proteinuria (LMWP), hypercalciuria, nephrolithiasis and chronic kidney disease (CKD). It is caused by mutations in the chloride voltage-gated channel 5 (CLCN5) gene (Dent disease-1), or in the OCRL gene (Dent disease-2). It is associated with chronic metabolic acidosis; however metabolic alkalosis has rarely been reported. Read More

J Coll Physicians Surg Pak 2022 May;32(5):623-626

Department of Urology, Trakya University Medical Faculty, Edirne, Turkey.

Objective: To evaluate the efficacy of retrograde intrarenal surgery (RIRS) and holmium laser lithotripsy in the treatment of symptomatic renal calyceal diverticular (CD) stones.

Study Design: A case series.

Place And Duration Of Study: Department of Urology, Hisar Intercontinental Hospital, from 2008 and 2019. Read More

BMC Med Genomics 2022 May 11;15(1):109. Epub 2022 May 11.

Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Objectives: Recurrent Kidney stone formation is a main medical problem imposing a significant burden on both healthcare and the economy worldwide. Environmental and genetic factors have been linked to a bigger risk of kidney stone formation. We aim to assess the role of methylation on recurrent stone formation in three target genes. Read More

Vet Surg 2022 May 10. Epub 2022 May 10.

College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.

Objective: To describe the ureteropyeloscopic removal of a nephrolith in a horse.

Animals: A 19 year old Hanoverian gelding with history of urolithiasis requiring surgical intervention.

Study Design: Case report METHODS: The horse presented with signs of abdominal straining and stranguria. Read More

BMJ Case Rep 2022 May 9;15(5). Epub 2022 May 9.

Department of Urology, James Cook University Hospital, Middlesbrough, UK.

Bladder stone is a known complication in a neurogenic bladder that can very rarely cause vesicovaginal fistula (VVF). We are presenting the case of a woman in her late 70s, bed bound with progressive multiple sclerosis (MS), who was referred to urology for consideration of suprapubic catheter due to difficulty in managing her indwelling urethral catheter. The ultrasonogram (USG) identified a 4. Read More

Saudi J Kidney Dis Transpl 2021 Sep-Oct;32(5):1461-1464

Department of Nephrology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.

Xanthogranulomatous pyelonephritis (XGPN) is an uncommon chronic destructive granulomatous inflammation of the kidney with variable clinical and radiological presentation. Due to its similarities to other benign and malignant pathologies, a high index of suspicion is required for preoperative diagnosis, which will ensure appropriate management of this condition. The invasion into the surrounding structures such as pararenal spaces, psoas muscle, small bowel, diaphragm, lung or soft tissues has been reported. Read More

J Avian Med Surg 2022 May;36(1):70-77

Division of Diagnostic Imaging, Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CM Utrecht, The Netherlands.

A 2-year-old domestic hen was presented for a 15-day history of intermittent left leg lameness. The owners also observed a decrease in egg quality during that period. Physical examination of the bird revealed a generalized weakness with a flattened pale comb. Read More

FASEB J 2022 Jun;36(6):e22340

Key Laboratory of Bio-Resource and Eco-Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.

The prevention role of Lactiplantibacillus plantarum against the formation of kidney stones has been increasingly recognized; its mechanism, however, has mainly been focused on inhibiting the inflammation in the colon in the gastrointestinal (GI) system, and the intestinal metabolites from microflora have not been revealed fully with regarding to the stone formation. In this study, we investigated the effect of L. plantarum J-15 on kidney stone formation in renal calcium oxalate (CaOx) rats induced by ethylene glycol and monitored the changes of intestinal microflora and their metabolites detected by 16S rRNA sequencing and widely targeted analysis, followed by the evaluation of the intestinal barrier function and inflammation levels in the colon, blood and kidney. Read More

Sisli Etfal Hastan Tip Bul 2022 28;56(1):70-76. Epub 2022 Mar 28.

Department of Urology, University of Health Sciences Turkey Bakırköy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

Objectives: Percutaneous nephrolithotomy (PNL) for upper urinary tract stones is a minimally invasive, effective treatment modality. Despite its high success rates, its potential complications pose a risk. In this study, we aimed to determine the risk factors associated with bleeding which is one of PNL's most important complications. Read More

Yonsei Med J 2022 May;63(5):440-445

Department of Urology, Severance Hospital, Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea.

Purpose: This study presents our initial experience with endoscopic combined intrarenal surgery (ECIRS) for large renal stones and compares the results of a propensity score-matched cohort of patients undergoing shock-wave lithotripsy (SWL).

Materials And Methods: A total of 100 adults underwent ECIRS for renal stones between August 2017 and January 2019. For comparison, 2172 patients who underwent a first session of SWL between January 2005 and May 2018 were included in the SWL cohort. Read More

Pol J Radiol 2022 11;87:e172-e176. Epub 2022 Mar 11.

Kovai Medical Centre and Hospital, Coimbatore, India.

Purpose: The aim of our study was to prospectively evaluate the role of third-generation, dual-source, dual-energy computed tomography (DECT) in the characterization of renal calculi, with ex vivo renal stone evaluation using Fourier transform infrared spectroscopy (IS) as the reference standard.

Material And Methods: In our study 50 patients with history suggestive of renal calculi were subjected to DECT using 100 kVp and Sn150 kVp. With DECT, renal stone attenuation at low and high kVp was attained, and the attenuation ratios were measured. Read More

Eur Rev Med Pharmacol Sci 2022 Apr;26(8):2867-2874

Department of Urology, Institute of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.

Objective: We aimed to evaluate the safety and efficacy of finger touching combined X-ray-guided percutaneous nephrolithotomy, and the feasibility of avoiding damage in medical staff caused by X-ray.

Patients And Methods: From January 2013 to December 2020, 640 cases of percutaneous nephrolithotomy were performed through the 18-24-F channel. Among those cases, 22 (3. Read More

Urolithiasis 2022 May 2. Epub 2022 May 2.

Department of Urology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.

Proton pump inhibitors (PPIs) are widely prescribed medications that have effects on both enteric and urinary solute handling with an unknown effect on risk of nephrolithiasis. Our objectives were to examine the association between PPI exposure and incident nephrolithiasis and to determine its effect on 24H urine chemistry. We performed a single-center retrospective study on patients diagnosed with gastroesophageal reflux disease (GERD) without a history of kidney stones. Read More

Cureus 2022 Mar 26;14(3):e23511. Epub 2022 Mar 26.

Internal Medicine and Diabetes and Endocrinology, Barking, Havering and Redbridge University Hospitals National Health Service (NHS) Trust, London, GBR.

Renal failure secondary to rhabdomyolysis due to statins is quite rare. We present a case of a 57-year-old patient who developed acute renal failure due to rhabdomyolysis secondary to atorvastatin. Interestingly, this patient had a similar presentation 27 years ago requiring dialysis only once resulting in complete resolution of symptoms. Read More

J Healthc Eng 2022 21;2022:4373416. Epub 2022 Apr 21.

Department of Urology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China.

Objective: To analyze the effect of ureteroscopy and retrolaparoscopy on urinary calculi and infection.

Method: A total of 64 patients with urinary calculi and infection who received treatment in our hospital from June 2018 to January 2018 were selected. According to the different treatment methods, they were divided into two groups: a control group and a study group. Read More

BMJ Case Rep 2022 Apr 29;15(4). Epub 2022 Apr 29.

Nephrology, KS Hegde Medical Academy, Mangalore, Karnataka, India.

A man in his 20s, a patient with chronic kidney disease with a baseline estimated glomerular filtration rate of 33 mL/min/1.73 m, who had an Indiana pouch continent urinary diversion procedure done at 6 years of age for bladder exstrophy, presented to the emergency room with sudden-onset progressive quadriparesis over 6 hours with power 1/5 in all the limbs with preserved reflexes. He was fully conscious and oriented, with stable vital signs. Read More

Scand J Urol 2022 Apr 28:1-9. Epub 2022 Apr 28.

Level 3 Chamberlain Building/School of Nursing Midwifery and Social Work, University of Queensland, St Lucia, Queensland, Australia.

Background: Since the 1950s a small number of centres have used sterile water injections (SWI) to treat renal colic pain. We undertook this review to determine the efficacy of SWI to manage the pain of renal colic.

Methods: We searched the electronic databases PubMed, Cochrane Central Register, CINAHL, and Scopus from database inception to 7 November 2021 for randomized controlled trials that met the inclusion criteria. Read More

BJUI Compass 2021 Jul 1;2(4):275-280. Epub 2021 Jul 1.

Department of Surgery St Vincent's Hospital Melbourne Fitzroy Australia.

Introduction And Objectives: Renal calculi are a common medical problem with incidence rates calculated to be approximately 6%-9% in men & 3%-4% in women worldwide. Incidence appears to be increasing. This study compares emergency presentations and unplanned readmissions between extracorporeal shock wave lithotripsy (SWL) and pyeloscopic stone treatment in the population of Victoria, Australia after 1-year follow-up. Read More

J Pediatr Urol 2022 Mar 28. Epub 2022 Mar 28.

Division of Paediatric Urology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, UP, -226014 , India. Electronic address:

Background: Minimal invasive approach is the current standard of care in the management of pediatric renal calculi. Current guidelines are clear with extra corporal shock wave lithotripsy (ESWL) and percutaneous nephrolithotomy (PCNL) for stone size less than and greater than 20 mm respectively. Although retrograde intrarenal surgery (RIRS) is well established in adults but literature on its role, safety and efficacy in children is sparsely available. Read More

J Endourol 2022 Apr 27. Epub 2022 Apr 27.

University Hospital of Wales, 97609, Urology Department, Cardiff, United Kingdom of Great Britain and Northern Ireland.

Introduction It is acknowledged that the COVID-19 pandemic has had a major impact on healthcare services around the globe with possible worse outcomes. It has resulted in stretch of resources with cancelled or delayed procedures. Patients with urinary calculi have also suffered the negative impact. Read More

Hinyokika Kiyo 2022 Mar;68(3):75-79

The Department of Urology, Ijinkai Takeda General Hospital.

Subcapsular renal hematoma is a complication of extracorporeal shock wave lithotripsy or percutaneous nephrolithotripsy. Although it can occur after transurethral ureterolithotripsy (TUL), there is no consensus on the risk factors, outcomes, and its management. This study aimed to elucidate the clinical courses of patients with subcapsular hematoma after TUL. Read More

J Laparoendosc Adv Surg Tech A 2022 Apr 25. Epub 2022 Apr 25.

Department of Urology, Biruni University School of Medicine, Istanbul, Turkey.

To determine the stone-free rates (SFR) with robot-assisted mini-endoscopic combined intrarenal surgery (mini-ECIRS) and evaluate the impact of intraoperative assessment of stone-free status compared to postoperative non-contrast computed tomography (NCCT) scan findings. A total of 42 consecutive patients (44 renal units) diagnosed with complex/multiple renal stones were enrolled and reviewed in a retrospective manner. While retrograde access with the flexible scope was performed by using Avicenna Roboflex, mini-percutaneous nephrolithotomy was performed through a 16. Read More