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Ultrasound Med Biol 2020 May 22. Epub 2020 May 22.

Department of Ultrasound Medicine, Peking University First Hospital, Beijing, P.R. China.

This study used contrast-enhanced ultrasound (CEUS) to evaluate changes in renal cortical blood perfusion after percutaneous transluminal renal angioplasty and stenting (PTRAS) for severe renal artery stenosis (RAS) (≥70%). CEUS was performed in 21 patients with 24 severe RASs that underwent PTRAS. Renal cortical perfusion was quantitatively evaluated by comparing time intensity curve (TIC) parameters for SonoVue (Bracco, Milan, Italy) contrast enhancement, including peak intensity (PI), time to peak (TTP), mean transmit time (MTT), curve ascending slope (S), area under the curve (AUC), AUC-wash-in and AUC-wash-out. Read More

Zhonghua Xin Xue Guan Bing Za Zhi 2020 May;48(5):378-385

Department of Epidemiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, China.

To investigate the association between smoking and the severity of coronary lesions among young and middle-aged female patients with acute coronary syndrome (ACS). Data of this study were derived from the Improving Care for Cardiovascular Disease in China (CCC)-ACS project, a collaborative study of the Chinese Society of Cardiology and the American Heart Association. Since 2014, the CCC-ACS project consecutively enrolled inpatients with ACS, systematically collected their clinical data and evaluated medical quality of these patients from 158 tertiary hospitals and 82 secondary hospitals across China. Read More

Hypertens Res 2020 May 22. Epub 2020 May 22.

Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.

Renal artery stenosis causes kidney ischemia, reducing the size of the affected kidney, which eventually results in atrophy. Although renal atrophy is considered irreversible, resolution of the ischemia occasionally restores kidney size when the cause is renal artery stenosis. Angioplasty is effective in patients with nonatherosclerotic renovascular diseases (non-ARVDs). Read More

BMJ Case Rep 2020 May 21;13(5). Epub 2020 May 21.

Department of Obstetrics and Gynecology, Cantonal Hospital Lucerne, Lucerne, Switzerland.

The midaortic syndrome (MAS) is a rare anomaly, characterised by narrowing of the distal aorta and its major branches. The most common symptom is severe arterial hypertension. The combination of hyponatremia, polyuria and renovascular hypertension caused by a unilateral renal artery stenosis is described as hyponatremic hypertensive syndrome. Read More

Int J Artif Organs 2020 May 22:391398820922231. Epub 2020 May 22.

Department of Cardiovascular Surgery (Emeritus), University of Geneva, Geneva, Switzerland.

In hemodialysis, vascular access is a key issue. The preferred access is an arteriovenous fistula on the non-dominant lower arm. If the natural vessels are insufficient for such access, the insertion of a synthetic vascular graft between artery and vein is an option to construct an arteriovenous shunt for punctures. Read More

J Cell Physiol 2020 May 19. Epub 2020 May 19.

Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.

Effective therapeutic strategies are needed to preserve renal function in patients with atherosclerotic renal artery stenosis (ARAS). Low-energy shockwave therapy (SW) and adipose tissue-derived mesenchymal stem/stromal cells (MSCs) both stimulate angiogenesis repair of stenotic kidney injury. This study tested the hypothesis that intrarenal delivery of adipose tissue-derived MSCs would enhance the capability of SW to preserve stenotic kidney function and structure. Read More

Age Ageing 2020 May 18. Epub 2020 May 18.

Erasmus MC University Medical Center, Section of Geriatrics, Department of Internal Medicine, Rotterdam, The Netherlands.

Background: Transcatheter aortic valve implantation (TAVI) brings symptom relief and improvement in health-related quality of life (HRQoL) in the majority of patients treated for symptomatic, severe aortic stenosis. However, there is a substantial group of patients that do not benefit from TAVI. The aim of this study is to investigate the impact of frailty on HRQoL 1 year after TAVI. Read More

Pol J Radiol 2020 3;85:e174-e177. Epub 2020 Apr 3.

Department of General Radiology, Interventional Radiology and Neuroradiology, Wroclaw Medical University, Wroclaw, Poland.

Purpose: Traditional digital subtraction angiography is still regarded as the gold standard in the diagnostics of transplant renal artery stenosis (TRAS). However, this procedure requires a high volume of iodine contrast medium for optimal visualisation of the renal artery. The aim of this study was to analyse both the usefulness and the safety of intra-arterial computed tomography angiography (IA-CTA) with ultra-low-volume iodine contrast administration in the diagnostic and therapeutic management of TRAS in patients with impaired renal transplant function. Read More

Atherosclerosis 2020 Apr 29;302:27-35. Epub 2020 Apr 29.

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA. Electronic address:

Background And Aims: Perivascular epicardial adipose tissue (pEAT) plays a key role in the progression of atherosclerosis, plaque rupture, and thrombosis. However, the relationship between pEAT and prognosis after revascularization of ST-segment elevation myocardial infarction (STEMI) is unknown. This study aimed to investigate the relationship between pEAT thickness and prognosis after STEMI. Read More

Cureus 2020 Apr 9;12(4):e7609. Epub 2020 Apr 9.

Radiology, James H. Quillen Veterans Affairs Medical Center, Johnson City, USA.

Renal hypoperfusion from renal artery stenosis (RAS) activates the renin-angiotensin system, which in turn causes volume overload and hypertension. Atherosclerosis and fibromuscular dysplasia are the most common causes of renal artery stenosis. Recurrent flash pulmonary edema, also known as Pickering syndrome, is commonly associated with bilateral renal artery stenosis. Read More

Heart Vessels 2020 May 11. Epub 2020 May 11.

Division of Cardiovascular Surgery, Department of Surgery, Kurume University School of Medicine, 67 Asahimachi, Kurume, 830-0011, Japan.

Degenerative aortic stenosis is the most common structural heart valve disease affecting the aging population. Catheter-based heart valve interventions are less invasive and very useful for very elderly patients. However, we often consider open heart surgery for these patients because of anatomical reasons and co-existing cardiac diseases, i. Read More

J Cardiothorac Surg 2020 May 11;15(1):84. Epub 2020 May 11.

Department of Orthopedics, Peking University Third Hospital, 49 North Garden Rd., Haidian District, Beijing, 100191, China.

Objectives: Does the manipulation of the off-pump CABG (OPCAB) in patient with depressed left ventricular function is better than on-pump CABG (ONCAB) approach in in-hospital mortality and morbidities? Here we undertook a meta-analysis of the best evidence available on the comparison of primary and second clinical outcomes of the off-pump and on-pump CABG.

Design: Systematic literature reviewer and meta-analysis.

Data Sources: PubMed, EMBASE, Web of science and Cochrane Center Registry of Controlled Trials were searched the studies which comparing the use of the off-pump CABG(OPCAB) and on-pump CABG (ONCAB) for patients with LVD during January 1990. Read More

Zhonghua Yi Xue Za Zhi 2020 May;100(18):1390-1395

Department of Cardiac Surgery, the Affiliated Hospital of Guizhou Medical University, Guiyang 550001, China.

To evaluate the clinical outcomes of on-pump total arterial revascularization with bilateral radial artery (BRA) and left internal mammary artery (LIMA) as conduits in coronary artery bypass grafting (CABG) patients with left ventricular dysfunction (LVD). All the perioperative medical records and follow-up results of coronary artery disease patients with left ventricular ejection fraction (LVEF) ≤ 40% undergoing CABG from 24 heart centers of 15 provinces and autonomous regions in China between July 2015 and December 2019 were retrospectively analyzed. A total of 87 consecutive patients (55 males and 32 females) underwent on-pump CABG with BRA and LIMA, with a mean age of (57. Read More

Can J Cardiol 2020 Feb 4. Epub 2020 Feb 4.

Division of Nephrology, Department of Medicine, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada. Electronic address:

Revascularization of atherosclerotic renal artery stenosis may cure hypertension, but paradoxically, improvement in systemic blood pressure in response to successful revascularization may precipitate ischemia in other organs affected by previously silent atherosclerotic disease. We describe bowel ischemia secondary to preexisting celiac artery stenosis after revascularisation. Prior knowledge of multivessel disease facilitated prompt diagnosis and management of this condition. Read More

Sisli Etfal Hastan Tip Bul 2019 21;53(3):221-227. Epub 2019 Aug 21.

Department of General Surgery, Istanbul Okan University, Faculty of Medicine, Istanbul, Turkey.

Objectives: The renal transplant program of Istanbul Okan University Hospital started in August 2017. Five cadaveric and 95 living donor kidney transplants have been performed for over 16 months. In this study, we aimed to share our experiences regarding kidney transplantation. Read More

Zhonghua Yi Xue Za Zhi 2020 May;100(17):1281-1283

Department of Sonography, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.

Cureus 2020 Apr 2;12(4):e7512. Epub 2020 Apr 2.

Radiology, Hospital of the University of Pennsylvania, Philadelphia, USA.

We present the case of a 66-year-old African-American male with end-stage renal disease (ESRD) secondary to polycystic kidney disease (PCKD), with well-controlled hypertension. He was placed on peritoneal dialysis for two years before successfully undergoing a cadaveric renal transplant. There was an immediate graft function with no relevant postoperative complications. Read More

Curr Opin Cardiol 2020 May 7. Epub 2020 May 7.

Department of Clinical Biochemistry, Royal Free Hospital Campus, University College London Medical School, University College London (UCL), London, UK.

Purpose Of Review: Vascular disease often affects more than one territory. Atherosclerosis is a global disease affecting multiple organs/systems. Cardiovascular risk factors are associated with an increased risk for the development of arterial disease in all vascular beds but differ in their individual impacts for each vascular bed. Read More

Postepy Kardiol Interwencyjnej 2020 Mar 29;16(1):65-75. Epub 2019 Dec 29.

Department of Diseases of Cardiac and Vessels, Jagiellonian University Medical College, John Paul II Hospital, Krakow, Poland.

Introduction: Restenosis (RS) following percutaneous angioplasty (PTA) of renal artery stenosis (RAS) might have an unfavourable impact on renal function and blood pressure (BP) outcomes.

Aim: To evaluate the prevalence and predictors of RS in patients treated with PTA for RAS, and the relationship between BP and renal function (RF) changes with RS.

Material And Methods: We analysed freedom from RS in 210 patients (age 64. Read More

Arthritis Res Ther 2020 May 4;22(1):103. Epub 2020 May 4.

Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education & National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Beijing, China.

Background: Large vessels could be involved in immunoglobulin (Ig)-G4-related disease (IgG4-RD). This study aimed to clarify the clinical features and evaluate the treatment efficacy for IgG4-RD with aortitis/periaortitis and periarteritis (PAO/PA).

Methods: This study prospectively enrolled 587 patients with IgG4-RD with a follow-up time of more than 6 months. Read More

Blood Press 2020 May 2:1-6. Epub 2020 May 2.

Department of Radiology, Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

To investigate contemporary results of percutaneous transluminal renal angioplasty (PTRA). A multicentre retrospective study analysing all patients treated with PTRA for primary symptomatic renal artery stenosis (RAS) between 2010 and 2013 at four tertiary centres. Procedures during the preceding four years were counted to evaluate for change in PTRA frequency. Read More

J Rheumatol 2020 May 1. Epub 2020 May 1.

Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, P. R. China; Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, P. R. China; Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, P. R. China; Center of Evidence-based Medicine, Fudan University, Shanghai, P. R. China. Address correspondence to Lindi Jiang, PhD, MD, 180 Fenglin Road, Department of Rheumatology, Zhongshan Hospital, Fudan, University, Shanghai 200032, P. R. China. E-mail:

Objective: To investigate the characteristics of patients with Takayasu arteritis (TA)- related renal artery stenosis and identify the predictors of medium-term adverse outcomes.

Methods: Data for 567 patients registered in a large prospective observational cohortthe East China Takayasu arteritis cohort-up to April 30, 2019, were retrospectively analyzed.

Results: Renal artery stenosis was confirmed in 172/567 (30. Read More

J Cardiovasc Surg (Torino) 2020 Apr 29. Epub 2020 Apr 29.

Department of Cardiovascular and Thoracic Surgery, University of Louisville School of Medicine, Louisville, KY, USA.

Background: Often, only saphenous vein grafts (SVGs) are used in emergent coronary artery bypass graft (CABG) procedures to provide quicker myocardial revascularization despite its lower long-term patency relative to the internal mammary artery (IMA) grafts. We examined differences between IMA and non-IMA graft recipients in emergent CABGs and its impact on in-hospital outcomes.

Methods: Retrospective review of Society of Thoracic Surgeon National Database was done to identify patients age >/= 18 years undergoing primary emergent isolated CABG between 2013 and 2016. Read More

Heart Vessels 2020 Apr 29. Epub 2020 Apr 29.

Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, 565-0871, Japan.

Recently developed coronary angiography with intraprocedural 320-row computed tomography can be performed in a catheterization laboratory (XACT) by injecting contrast medium from a place close to the coronary arteries, thereby requiring a minimal amount of contrast medium. However, its clinical application has not yet been established. This study aimed to evaluate the diagnostic accuracy of XACT angiography with a minimal volume of contrast medium in patients with suspected coronary artery disease (CAD). Read More

Eur Spine J 2020 Apr 23. Epub 2020 Apr 23.

Department of Neurosurgery, Central Theater General Hospital of Chinese PLA, No. 627 Wuluo Road, Wuhan, China.

Purpose: Spinal DSA is the "gold standard" technique to identify the spinal vascular diseases with venous hypertensive myelopathy (VHM). However, sometimes spinal DSA can find nothing in patients with confirmed spinal vascular anomalies. Many of the reasons are avoidable technical factors. Read More

Case Rep Nephrol 2020 9;2020:8364176. Epub 2020 Apr 9.

Nephrology Unit, Medical Department, National University of Malaysia Medical Centre, Kuala Lumpur, Malaysia.

Background: Superior mesenteric artery (SMA) syndrome is a rare cause of upper gastrointestinal obstruction leading to acute kidney injury (AKI).

Methods: We report a case of 23-year-old army personnel who presented with persistent vomiting leading to severe hypokalaemia, metabolic alkalosis, and acute kidney injury resulting in cardiorespiratory arrest.

Results: After successful resuscitation, he was supported with haemodialysis and aggressive electrolytes correction. Read More

Int J Cardiol Heart Vasc 2020 Apr 30;27:100475. Epub 2020 Jan 30.

Div. of Cardiology, St. Josefs-Hospital, Beethovenstr. 20, 65189 Wiesbaden, Germany.

Background: Renal artery stenosis (RAS) can lead to hypertension and renal failure. Nevertheless, its treatment by percutaneous transluminal renal angioplasty (PTRA) remains controversial. It is unknown, whether patients with global kidney ischemia (GKI), that means patients with bilateral RAS or RAS with a single functioning kidney, may benefit from PTRA or not. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2020 Apr;23(4):384-389

Department of General Surgery, the Second Xiangya Hospital, Central South University, Changsha 410011, China.

To explore the safety and feasibility of da Vinci robot surgical systems in natural orifice specimen extraction surgery (NOSES) for rectal neoplasms. A descriptive cohort study was used. Inclusion criteria: (1) age ≥18 years old; (2) diagnosis of rectal cancer by biopsy via colonoscopy or benign neoplasm locating in rectum that could not be resected locally through the anus; (3) R0 resection can be achieved by preoperative evaluation; (4) the CDmax (maximum circumferential diameter) was ≤5 cm or specimens could still be extracted from the anus despite a CDmax exceeding 5 cm but was along the longitudinal axis of the rectum. Read More

Heart Lung Circ 2020 Apr 8. Epub 2020 Apr 8.

Queensland Heart Institute, Brisbane, Qld, Australia; Cardiovascular Clinics, Brisbane, Qld, Australia; University of Queensland, Brisbane, Qld, Australia; St Andrew's War Memorial Hospital, Brisbane, Qld, Australia. Electronic address:

Background: Transcatheter aortic valve implantation (TAVI) was first performed in Australia in 2008 with a steady increase in the number of implanting centres from seven in 2008 to 42 in 2018 (24 private and 18 public hospitals). There is limited published data on outcomes from Australian centres and no published data from Australian private hospitals. We describe outcomes of the first 300 cases at Queensland's first TAVI implanting private hospital. Read More

J Geriatr Cardiol 2020 Mar;17(3):173-174

Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, the Chinese University of Hong Kong, Hong Kong, China.

CEN Case Rep 2020 Apr 10. Epub 2020 Apr 10.

Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan.

Ask-Upmark kidney (AUK) is a scarred segment of the kidney, characterized by formation of primitive tubular and glomerular structures, and sporadically diagnosed as a cause of hypertension (HTN). A 6-year-old girl with neurofibromatosis type 1 (NF1) and moyamoya syndrome had severe HTN. Based on past history, she had HTN at the age of 1. Read More

Khirurgiia (Mosk) 2020 (3):43-47

Kemerovo State Medical University of the Ministry of Health of Russia, Kemerovo, Russia.

Objective: A retrospective analysis of in-hospital results of renal artery stenting in patients with multifocal atherosclerosis.

Material And Methods: The study included 19 patients who underwent stenting for renal artery stenosis for the period 2011-2015 in the Kemerovo Cardiology Dispensary. Renal function was assessed considering glomerular filtration rate (GFR). Read More

Biomark Med 2020 Apr 9;14(6):433-440. Epub 2020 Apr 9.

Department of Cardiology, Faculty of Hamidiye Medicine, University of Health Science Turkey, Ankara Research & Education Hospital, Ankara, Turkey.

We investigated the relationship between mild renal dysfunction (MRD) and the presence of coronary artery disease (CAD) in people under 60 years of age.  A total of 634 (317 patients with vessel stenosis ≥50% and 317 with normal angiography) individuals diagnosed with stable angina pectoris and estimated glomerular filtration rate (eGFR) ≥60 ml/min/1.73 m were included in the present study. Read More

J Nephrol 2020 Apr 8. Epub 2020 Apr 8.

Nephrology Units at University "Magna Graecia", Catanzaro, Italy.

The increased prevalence of chronic kidney disease (CKD) in elderly patients recognizes, as main cause, the long-term exposure to atherosclerosis and hypertension. Chronic ischemic damage due to critical renal arterial stenosis induces oxidative stress and intra-renal inflammation, resulting in fibrosis and microvascular remodelling, that is the histological picture of atherosclerotic renal vascular disease (ARVD). The concomitant presence of a long history of hypertension may generate intimal thickening and luminal narrowing of renal arteries and arterioles, glomerulosclerosis, interstitial fibrosis and tubular atrophy, more typically expression of hypertensive nephropathy. Read More

Clin Hypertens 2020 1;26. Epub 2020 Apr 1.

1Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, USA.

Background: Renal artery stenosis is a notorious cause of secondary hypertension which classically presents as chronic refractory hypertension, recurrent flash pulmonary edema or renal insufficiency after initiation of an angiotensin converting enzyme inhibitor. Rarely, there have been reported cases of pregnant patients presenting with new onset or superimposed preeclampsia secondary to renovascular hypertension. In this subset of patients, renovascular hypertension carries significantly higher risks including obstetric, fetal and medical emergencies and death. Read More

J Vasc Surg 2020 Apr 2. Epub 2020 Apr 2.

Multimodality Medical Imaging M3i Group, Faculty of Science and Technology, Technical Medical Centre, University of Twente, Enschede, The Netherlands; Department of Vascular Surgery, Rijnstate, Arnhem, The Netherlands.

Objective: To evaluate the proximal stability of the chimney endovascular aneurysm sealing configuration (chEVAS) during the cardiac cycle by investigating the cardiac pulsatility-induced movement and deformation.

Methods: We retrospectively analyzed postoperative electrocardiogram-gated computed tomography angiography scans of 11 chEVAS cases (9 primary chEVAS plus 2 chEVAS-in-chEVAS). ChEVAS procedures were conducted between September 2013 and June 2016. Read More

Cell Transplant 2020 Jan-Dec;29:963689720917342

Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.

Endothelial progenitor cells (EPCs) patrols the circulation and contributes to endothelial cell regeneration. Atherosclerotic renal artery stenosis (ARAS) induces microvascular loss in the stenotic kidney (STK). Low-energy shockwave therapy (SW) can induce angiogenesis and restore the STK microcirculation, but the underlying mechanism remains unclear. Read More

PLoS One 2020 1;15(4):e0230020. Epub 2020 Apr 1.

Nephrology Unit of Magna Graecia University in Catanzaro, Catanzaro, Italy.

Background: High ultrasound renal resistive index (RI) predicts poor cardiorenal outcomes in chronic kidney disease (CKD) and has recently emerged as a marker of nephroprotective drugs response. Thus, having a risk profile of CKD patients with abnormal RI may be relevant for the clinicians.

Methods: Consecutive patients referred to our non-dialysis CKD clinic from 01/01/2016 to 01/12/2016, were evaluated by clinical and ultrasound analysis. Read More

J Stroke Cerebrovasc Dis 2020 Mar 28:104786. Epub 2020 Mar 28.

Department of Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan.

Background: The de novo occurrence of renal artery stenosis in renal arteries that were angiographically confirmed to be normal in the past has never been reported before in patients with moyamoya disease.

Case Description: During the long-term follow-up of pediatric patients with moyamoya disease, we observed 3 patients who developed de novo renal artery stenosis in arteries that had been angiographically confirmed to be normal 1 year after the surgery (7 years on average, ranging from 4 to 11 years). All of these patients were neurologically stable after successful indirect bypass surgery during childhood. Read More

Future Cardiol 2020 Mar 31. Epub 2020 Mar 31.

Coburg Clinic, Department of Cardiology, Angiology & Pulmonology, Coburg, Germany.

The use of shockwave lithotripsy for the treatment of heavily calcified atherosclerotic plaques before stenting showed great results in terms of feasibility and safety with favorable initial success. Evidence suggests that it is a useful tool to treat calcified lesions in peripheral and coronary arteries. Here, we describe the case of a patient with calcified renal artery stenosis successfully treated with the shockwave lithotripsy system. Read More

Hypertension 2020 May 30;75(5):1223-1232. Epub 2020 Mar 30.

From the Division of Nephrology and Hypertension (T.S., A.E., X.Z., Y.Z., J.D.K., H.T., K.L.J., J.R.W., L.O.L.), Mayo Clinic, Rochester, MN.

Metabolic syndrome (MetS) profoundly changes the contents of mesenchymal stem cells and mesenchymal stem cells-derived extracellular vesicles (EVs). The anti-inflammatory TGF-β (transforming growth factor-β) is selectively enriched in EVs from Lean but not from MetS pigs, but the functional impact of this endowment remains unknown. We hypothesized that Lean-EVs more effectively induce regulatory T cells in injured kidneys. Read More

Indian Pediatr 2020 May 12;57(5):443-451. Epub 2020 Mar 12.

Division of Nephrology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Renovascular hypertension (RVHTN) is an important contributor to secondary etiologies of hypertension in the pediatric population. A delay in diagnosis can be associated with adverse outcomes. The etiologies of renal artery stenosis (RAS) vary from anatomical, inflammatory, genetic syndromes, intra-luminal, external compression and idiopathic. Read More

Clin Nephrol 2020 Jun;93(6):300-305

An elderly Japanese woman with bilateral renal artery occlusion who developed massive proteinuria after unilateral percutaneous transluminal renal angioplasty (PTRA) is reported. She had a history of percutaneous coronary intervention and subsequently developed refractory hypertension. She was diagnosed with renovascular hypertension caused by bilateral total occlusion of the renal arteries, and underwent PTRA for the left renal artery. Read More

J Investig Med High Impact Case Rep 2020 Jan-Dec;8:2324709620914793

Bassett Medical Center, Cooperstown, NY, USA.

Renal artery stenosis is a cause of resistant hypertension, which can present with several features such as severe hypertension, deterioration of renal function (with or without associated angiotensin-converting inhibitor or angiotensin receptor blocker therapy), and flash pulmonary edema. When evaluating for the presence of renal artery stenosis, the most widely utilized imaging modalities are duplex ultrasonography and computed tomography angiography. In this article, we discuss the case of a 77-year-old female who presented with shortness of breath and mild pulmonary edema, secondary to hypertensive emergency. Read More

J Am Heart Assoc 2020 Apr 21;9(7):e014072. Epub 2020 Mar 21.

Department of Medicine University of Toledo College of Medicine and Life Sciences Toledo OH.

Background Renal artery stenosis is a common cause of renal ischemia, contributing to the development of chronic kidney disease. To investigate the role of local CD40 expression in renal artery stenosis, Goldblatt 2-kidney 1-clip surgery was performed on hypertensive Dahl salt-sensitive rats (S rats) and genetically modified S rats in which CD40 function is abolished (). Methods and Results Four weeks following the 2-kidney 1-clip procedure, rats demonstrated significantly reduced blood pressure and renal fibrosis in the ischemic kidneys compared with S rat controls. Read More

Biomech Model Mechanobiol 2020 Mar 21. Epub 2020 Mar 21.

Department of Applied Mechanics, Sichuan University, Chengdu, 610065, People's Republic of China.

Saphenous vein graft (SVG) bypass placement is regarded as the optimal option for renal artery stenosis, which usually causes secondary hypertension and poor renal perfusion. Using computational fluid dynamics, this study aimed to investigate the underlying hemodynamic mechanism of the vein aneurysm and stenosis after aortorenal bypass surgery. Three-dimensional models were reconstructed based on computed tomographic angiography images of a 20-year-old female patient who suffered from uncontrollable hypertension using the image processing package Mimics (Materialise). Read More

J Thromb Thrombolysis 2020 May;49(4):511-521

Department of Translational Medicine, Ospedale "Maggiore Della Carità", Eastern Piedmont University, C.so Mazzini, 18, 28100, Novara, Italy.

The impact of platelet parameters on the cardiovascular risk is still debated. Gender differences in platelet volume indexes and turnover have been previously reported, potentially conditioning their role in the development of coronary artery disease (CAD). However, few studies have addressed, so far, the impact of gender on the immature platelet fraction (IPF) and count (IPC) and their relationship with CAD. Read More

Chin Med J (Engl) 2020 Apr;133(8):975-981

Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

Background: Takayasu arteritis-induced renal arteritis (TARA), commonly seen in Takayasu arteritis (TA), has become one of the main causes of poor prognosis and early mortality in patients with TA. TARA progressing into Takayasu arteritis-induced renal artery stenosis (TARAS), could lead to severe complications including malignant hypertension, cardiac-cerebral vascular disease, and ischemic nephropathy. Since there existed no guidelines on treatments, this study aimed to review the comprehensive treatments for TARA. Read More

Ulus Travma Acil Cerrahi Derg 2020 Mar;26(2):197-202

Department of Urology, İstanbul University İstanbul Faculty of Medicine, İstanbul-Turkey.

Background: This study aims to review retrospectively the surgical and urological complications encountered in 789 cases of living-related donor kidney transplantations (LRDKTs).

Methods: In this study, the clinical records of 789 LRDKTs, which were performed between 1983 and 2017, were reviewed retrospectively concerning surgical and urological complications.

Results: Overall, urological and surgical complications were encountered in 87 (11. Read More

Am J Hypertens 2020 Mar 17. Epub 2020 Mar 17.

Department of Internal Medicine, Division of Nephrology and Hypertension, Rochester, MN.

Background: Mitochondria modulate several aspects of endothelial cell (EC) function, but may be damaged during renal disease. We hypothesized that the ischemic and metabolic constituents of swine renovascular disease (RVD) induce mitochondrial damage and impair the function of renal artery ECs.

Methods: Domestic pigs were studied after 16 weeks of diet-induced metabolic syndrome (MetS), renal artery stenosis (RAS), or coexisting MetS and RAS, and Lean pigs served as control (n=6 each). Read More