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Respiration 2019 Jan 24:1-12. Epub 2019 Jan 24.

Department of Surgical, Oncological and Oral Science (Di.Chir.On.S.), Section of Anesthesia, Analgesia, Intensive Care and Emergency, Policlinico Paolo Giaccone, University of Palermo, Palermo, Italy.

Background: Noninvasive mechanical ventilation (NIV) is an effective treatment in patients with neuromuscular diseases (NMD) to improve symptoms, quality of life, and survival.

Summary: NIV should be used early in the course of respiratory muscle involvement in NMD patients and its requirements may increase over time. Therefore, training on technical equipment at home and advice on problem solving are warranted. Read More

Medicine (Baltimore) 2019 Jan;98(2):e13895

Palliative Care Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola.

Chronic pain is often difficult to treat, requiring a comprehensive multidisciplinary therapeutic intervention and a high level of management expertise.This is particularly true for patients who are unresponsive to standard treatments for chronic pain, for which Scrambler Therapy (ST) is indicated. The aim of the present study was to evaluate the impact of ST on patient-reported moderate to severe chronic pain. Read More

Pediatr Phys Ther 2019 01;31(1):61-66

Department of Pediatrics (Drs Kiefer and Wong), University of Massachusetts Medical School, Worcester, Massachusetts; Division of Occupational Therapy and Physical Therapy (Drs Kiefer, Bonarrigo, Quatman-Yates, and Fowler) and Division of Neurology (Drs Kiefer, Bonarrigo, Fowler, Horn, and Wong), Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics (Dr Horn), University of Cincinnati College of Medicine, Cincinnati, Ohio; Department of Physical Therapy (Dr Quatman-Yates), The Ohio State University, Columbus, Ohio.

Purpose: This study characterizes the progressive loss of ankle dorsiflexion range of motion in boys with Duchenne muscular dystrophy (DMD), the relationship to functional decline, and the implications for physical therapy management.

Methods: Longitudinal data for 332 boys with DMD were extracted from medical records and analyzed. Summary statistics for age, number of visits, ankle dorsiflexion measures, and North Star Ambulatory Assessment (NSAA) scores were computed. Read More

Neurol Sci 2018 Dec 15. Epub 2018 Dec 15.

Neurology IV - Neuroimmunology and Neuromuscular Diseases Unit, Fondazione IRCCS Istituto Neurologico "Carlo Besta", Via Celoria 11, 20133, Milan, Italy.

Congenital myasthenic syndromes (CMS) are genetic disorders due to mutations in genes encoding proteins involved in the neuromuscular junction structure and function. CMS usually present in young children, but perinatal and adult onset has been reported. Clinical presentation is highly heterogeneous, ranging from mild symptoms to severe manifestations, sometimes with life-threatening respiratory episodes, especially in the first decade of life. Read More

Medicine (Baltimore) 2018 Dec;97(49):e13455

Department of Physical Medicine and Rehabilitation, Tung's Taichung Metroharbor Hospital, Taichung, Taiwan.

Rationale: Compressive radial neuropathy by a synovial cyst in the radial tunnel during pregnancy is a rare occurrence. The management of radial nerve compression caused by a synovial cyst in a pregnant patient is a surgical dilemma owing to the fetal and maternal risks of treatment.

Patient Concerns And Diagnosis: A 37-year-old pregnant woman presented with progressive forearm pain at the gestational age of 12 weeks. Read More

J Child Neurol 2018 Dec 5:883073818811544. Epub 2018 Dec 5.

1 Ersta Sköndal Bräcke University College, Department of Health Care Sciences, Palliative Research Centre, Stockholm, Sweden.

Background And Aims:: Children with severe spinal muscular atrophy have complex care needs due to progressive muscle weakness, eventually leading to respiratory failure. To design a care system adapted to families' needs, more knowledge about parents' experience of care and its coordination between settings is required. This study explores (1) whether parents felt that health professionals took every opportunity to help the child feel as good as possible, (2) parents' satisfaction with various care settings, and (3) parents' satisfaction with coordination between settings. Read More

BMC Complement Altern Med 2018 Nov 26;18(1):310. Epub 2018 Nov 26.

Department of Medical Rehabilitation, Faculty of Health Sciences and Technology, University of Nigeria|, Enugu Campus, Enugu State, Nigeria.

Background: Many studies on transcutaneous electrical nerve stimulation (TENS) had been undertaken to explore its pain relieving efficiency on several medicals/surgical conditions but none, specifically, had been carried out to determine the effect it has on post-injection sciatic pain (PISP) which comes about from wrong administration of intramuscular pain. This study aims to assess the effects of TENS in the management of PISP.

Methods: A total of 72 PISP subjects comprising 40 test subjects and 32 control subjects participated in a non-randomized controlled clinical trial in the current study. Read More

Pain Res Manag 2018 1;2018:2930632. Epub 2018 Oct 1.

Department of Physical Therapy Science, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki 852-8520, Japan.

Purpose: We conducted a systematic review and meta-analysis to investigate the effects of the following physical-agent modalities for pain relief in fibromyalgia (FM) patients.

Methods: We identified randomized controlled studies of adults with FM in the MEDLINE, CINAHL, and PEDro databases. The primary outcome measure was pain relief measured by a visual analogue scale (VAS), and the secondary outcome measures of interest were subjective improvements in the number of tender points, Fibromyalgia Impact Questionnaire (FIQ), and quality of life (QOL) scores. Read More

J Neuromuscul Dis 2018 ;5(4):431-438

Department of Neurology, Radboud University Medical Center, Nijmegen, The Netherlands.

Background And Objective: Non-invasive ventilation (NIV) is an established treatment for respiratory failure in patients with amyotrophic lateral sclerosis (ALS). Several studies have shown room for improvement with regard to respiratory care for ALS patients, including latency of referral. These studies focused on the time period starting at the moment of referral to a home ventilation service (HVS) onwards. Read More

Pediatr Crit Care Med 2019 Jan;20(1):54-61

Department of Anesthesiology and Critical Care Medicine, Charlotte R. Bloomberg Children's Center, Johns Hopkins University School of Medicine, Baltimore, MD.

Objectives: To review important articles on pain, sedation, sleep, and delirium in the field of pediatric critical care published subsequent to the fifth edition of the Rogers' Textbook of Pediatric Critical Care.

Data Sources: The U.S. Read More

BMJ Case Rep 2018 Oct 16;2018. Epub 2018 Oct 16.

USAT College of Medicine, University of Science, Arts & Technology, Olveston, Montserrat.

A 34-year-old man with a history of gunshot wound (GSW) to the right upper chest developed secondary aortic valve endocarditis (AVE) and was treated with an artificial valve placement (AVP). Three months after, he presented to an outpatient pain management clinic right arm pain and was diagnosed with complex regional pain syndrome type II (CRPS II). The patient underwent a diagnostic sympathetic ganglion block, before undergoing endoscopic thoracic sympathectomy surgery. Read More

Eur J Oncol Nurs 2018 Oct 27;36:135-141. Epub 2018 Sep 27.

School of Nursing, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.

Purpose: The study aimed at uncovering the symptom experience of neurotoxicity, self-adopted approaches and perspectives in managing chemotherapy-induced peripheral neuropathic (CIPN) symptoms in a sample of Chinese cancer survivors.

Methods: A qualitative descriptive study was used to explore individual experiences. A purposive sample of 12 female participants experiencing CIPN was invited to semi-structured interviews who were part of a larger prospective observational study investigating the natural progression and risk factors of CIPN. Read More

J Neuromuscul Dis 2018 ;5(4):481-495

New York State Department of Health, Albany, New York, USA.

Dystrophinopathies are caused by mutations in DMD resulting in progressive muscle weakness. They are historically divided into the more severe Duchenne (DMD) and milder Becker (BMD) muscular dystrophy phenotypes. Classification is important for research and clinical care. Read More

J Neurol 2018 Dec 10;265(12):2927-2933. Epub 2018 Oct 10.

Division of Neuroscience, Department of Neurology, Institute of Experimental Neurology (INSPE), IRCCS San Raffaele Scientific Institute, Milan, Italy.

Although anti-myelin-associated glycoprotein (MAG) antibody neuropathy is reported as a slowly progressive disease, it can lead to significant disability and impairment of health-related quality of life (HR-QoL) and social participation. The aim of this cross-sectional study was to evaluate the functioning and HR-QoL determinants in 67 patients with anti-MAG neuropathy in terms of the International Classification of Functioning, Disability, and Health (ICF). Evaluations included: Medical Research Council (MRC) sum score, Sensory Modality Sum score (SMS), Berg balance scale (BBS), Fatigue Severity Scale (FSS), Visual Analogue Scale (VAS) for pain, 9-Hole Peg Test (9-HPT), 6-min Walk Distance (6MWD), Impact on Participation and Autonomy (IPA) and the physical component score (PCS) and mental component score (MCS) of the short-form-36 health status scale (SF-36) HR-QoL measure. Read More

J Neurol 2018 Dec 8;265(12):2916-2926. Epub 2018 Oct 8.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

Background: The majority of patients presenting with suspected clinical cauda equina syndrome (CES) have no identifiable structural cause for their symptoms ('scan-negative' CES). Understanding these patients aids clinical differentiation and management in CES.

Methods: A retrospective electronic note review was undertaken of patients presenting with suspected CES, defined as ≥ 1 of acute bladder, bowel, sexual dysfunction or saddle numbness, to a regional neurosciences centre. Read More

Phys Med Rehabil Clin N Am 2018 11 17;29(4):761-776. Epub 2018 Sep 17.

Physical Medicine and Rehabilitation, Swedish Health Services, 1600 E. Jefferson, Suite 300, Seattle, WA 98122, USA. Electronic address:

Learning to recognize the various clinical and electrodiagnostic patterns of peripheral neuropathy enables a targeted approach to etiologic investigation, and subsequently guides patient discussions of self-management, disease course, and prognosis. Moreover, as advancements in neuropathology and pharmacotherapy inform the many etiologies of polyneuropathy, it is imperative for clinicians to identify the underlying etiology to appropriately guide treatment options and prevent complications. Read More

Phys Med Rehabil Clin N Am 2018 11 5;29(4):701-719. Epub 2018 Sep 5.

Oncology Rehabilitation, University of Kansas, Comprehensive Spine Center, 4000 Cambridge Street, Kansas City, KS 66160, USA. Electronic address:

Cancer treatments continue to advance the management and survival of patients. However, use of these regimens can lead to significant side effects both temporary and permanent. Neuromuscular side effects include chemotherapy-induced peripheral neuropathy and radiation fibrosis syndrome. Read More

Phys Med Rehabil Clin N Am 2018 11 7;29(4):669-680. Epub 2018 Sep 7.

Department of Rehabilitation Medicine, University of Washington, 325 Ninth Avenue, Box 359612, Seattle, WA 98104, USA.

Electrodiagnostic testing provides insight into subclinical aspects of disease in amyotrophic lateral sclerosis and helps to diagnose and exclude other diagnoses. It may also help to manage or track disease progression. Mapping the extent of subclinical disease may guide the clinician to supportive interventions. Read More

Medicine (Baltimore) 2018 Oct;97(40):e12303

Department of Rehabilitation Medicine and Rehabilitation Institute of Neuromuscular Disease.

In advanced Duchenne muscular dystrophy (DMD), patients with high bone fracture risk due to osteoporosis, it is difficult to measure spinal bone mineral density (BMD) because of maintaining proper posture. This study began with the idea that if we diagnose and manage osteoporosis by predicting spinal BMD through easily testable radial BMD, we could prevent fracture and improve quality of life in DMD patients. In 61 DMD patients aged 20 years or older who were admitted to Gangnam Severance Hospital from April 2013 to May 2015, radial BMD and spinal BMD were measured to compare their Z-scores. Read More

Prosthet Orthot Int 2018 Oct 4:309364618796852. Epub 2018 Oct 4.

1 University of Central Lancashire, Preston, UK.

Background: Use of proprioceptive knee braces to control symptomology by altering neuromuscular control mechanisms has been shown in patellofemoral pain. Although their potential in patients with knee osteoarthritis is vast, little research has examined their efficacy.

Objectives: This study examines the effect of a proprioceptive knee brace on lower limb kinematics and kinetics in healthy participants and in participants with OA. Read More

Nutrients 2018 Oct 1;10(10). Epub 2018 Oct 1.

Department of Health, Exercise and Sports Science, University of New Mexico, Albuquerque, NM 87131, USA.

This study investigated the effect of branched-chain amino acid (BCAA) supplementation on recovery from eccentric exercise. Twenty males ingested either a BCAA supplement or placebo (PLCB) prior to and following eccentric exercise. Creatine kinase (CK), vertical jump (VJ), maximal voluntary isometric contraction (MVIC), jump squat (JS) and perceived soreness were assessed. Read More

Trials 2018 Sep 29;19(1):526. Epub 2018 Sep 29.

Departmetn of Surgery and Research Institute for Medicinal Sciences, College of Medicine, Chungnam National University, 33 Munwha-ro, Jung-gu, Daejeon, Korea.

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a progressive, enduring, and sometimes irreversible neurotoxic symptom that occurs in 30-40% of chemotherapy-treated cancer patients. CIPN negatively affects both the patient's abilities to perform daily activities and their health-related quality of life (HRQOL) after chemotherapy treatment. Although this neuropathy has been treated with duloxetine and/or gabapentin, limited therapeutic benefits have been reported, thereby necessitating the development of an integrated approach that combines pharmacological management and complementary methods such as acupuncture and electric nerve stimulation. Read More

J Foot Ankle Res 2018 24;11:54. Epub 2018 Sep 24.

2Podiatry Department, School of Health Sciences, Queen Margaret University, Edinburgh, UK.

Background: This evaluation sought to determine current Charcot neuroarthropathy (CN) diabetes patient education practices among Scottish National Health Service (NHS) and academic podiatrists and evaluate novel visual tools and develop expert consensus for future practice.

Methods: Questionnaires collected mixed qualitative and quantitative responses, analysed concurrently within a convergence coding matrix. Delphi methodology permitted member-checking and agreement of consensus over two rounds. Read More

Acta Clin Croat 2018 Mar;57(1):16-21

Division of Rheumatology and Clinical Immunology, Department of Internal Medicine, School of Medicine, University of Zagreb, Dubrava University Hospital, Zagreb, Croatia.

The aim of the study was to determine the prevalence of neuropathic pain in knee osteoarthritis patients using painDETECT questionnaire, and to evaluate correlations between pain intensity, gender, age and types of treatment, and the presence of neuropathic pain. The study included 122 patients. All participants completed a questionnaire on sociodemographic data, duration of symp-toms, types of treatment and preventable risk factors (body mass index and waist circumference). Read More

Top Companion Anim Med 2018 Jun 16;33(2):49-57. Epub 2018 May 16.

Neurology/Neurosurgery Department, Long Island Veterinary Specialists, Plainview, NY, USA; Fipapharm, Mont-Saint-Aignan, France. Electronic address:

The increase in client willingness to pursue surgical procedures, the heightened perceived value of veterinary patients, and the desire to provide comprehensive medical care have driven the recent demand of using an integrative treatment approach in veterinary rehabilitation. Physical therapy following neurologic injury has been the standard of care in human medicine for decades, whereas similar rehabilitation techniques have only recently been adapted and utilized in veterinary medicine. Spinal cord injury is the most common neurologic disease currently addressed by veterinary rehabilitation specialists and will be the primary focus of this review; however, research in other neurologic conditions will also be discussed. Read More

J Pediatr Orthop 2019 Jan;39(1):e39-e43

Department of Orthopaedics, University of British Columbia.

Background: Infants with dislocated irreducible (D/I) hips can be substantially harder to treat than infants with dislocated but reducible hips. The purpose of this study was to compare treatment methods and outcomes for infants with D/I hips in order to optimize management of this difficult patient cohort.

Methods: A multicenter prospective hip dysplasia study database was analyzed from 2010 to 2016. Read More

Curr Sports Med Rep 2018 Sep;17(9):302-307

Department of Orthopaedics, University of Utah School of Medicine, Salt Lake City, UT.

Advances in pharmacologic management of inflammatory conditions have allowed those living with these conditions to pursue fitness activities previously difficult due to functional limitations. With that said, many patients with inflammatory arthritis are still not active enough. In this article, we review specific exercise recommendations for a number of inflammatory conditions with a focus on overall health promotion and cardiovascular disease risk reduction, discuss exercise as an adjunct to pharmacologic disease management, and review potential risks of sport participation for athletes with inflammatory arthritis conditions. Read More

Scand J Trauma Resusc Emerg Med 2018 Sep 10;26(1):76. Epub 2018 Sep 10.

Institute for Research in Operative Medicine (IFOM), University of Witten / Herdecke, Cologne, Germany.

Background: Peripheral nerve injury (PNI) as an adjunct lesion in patients with upper extremity trauma has not been investigated in a Central European setting so far, despite of its devastating long-term consequences. This study evaluates a large multinational trauma registry for prevalence, mechanisms, injury severity and outcome characteristics of upper limb nerve lesions.

Methods: After formal approval the TraumaRegister DGU® (TR-DGU) was searched for severely injured cases with upper extremity involvement between 2002 and 2015. Read More

Medicine (Baltimore) 2018 Sep;97(36):e12247

Department of Physical and Rehabilitation Medicine, Hacettepe University Medical School, Ankara, Turkey.

Rotator cuff tendon tears are prevalent in patients with shoulder pain, the third most common musculoskeletal complaint. As shoulders are largely innervated by cervical nerves, it seems possible that rotator cuff pathology could have an association with cervical spine disorders, although few studies have investigated this possibility. This study aimed to explore the association between rotator cuff tendon tears and cervical radiculopathy (at C5 and C6 levels) in the shoulder pain population. Read More

Br J Sports Med 2018 Sep 7. Epub 2018 Sep 7.

Department of Orthopaedic Surgery and Sports Medicine, Centre Orthopédique Santy, FIFA Medical Centre of Excellence, Groupe Ramsay-Generale de Sante, Hôpital Privé Jean Mermoz, Lyon, France.

Objective: To determine whether reported therapeutic interventions for arthrogenic muscle inhibition (AMI) in patients with ACL injuries, following ACL reconstruction, or in laboratory studies of AMI, are effective in improving quadriceps activation failure when compared with standard therapy in control groups.

Design: A scoping review of the efficacy of interventions was conducted in accordance with the methodological framework of Arksey and O'Malley and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Search terms included 'arthrogenic muscle inhibition', 'quadriceps activation following knee injuries', 'anterior cruciate' or 'knee' combined with 'quadriceps activation', 'quadriceps inhibition', 'corticomotor', 'arthrogenic', 'brain activation' and 'neuroplasticity'. Read More

Medicina (B Aires) 2018 ;78 Suppl 1:1-23

Consultora del Departamento de Neuropatología, Instituto de Investigaciones Neurológicas-FLENI y Hospital Nacional de Pediatría Prof. Dr. Juan P. Garrahan, Buenos Aires, Argentina.

Pompe's disease (PD) is an infrequent metabolic autosomic recessive disorder produced by the lack or deficiency of the acid alpha-glucosidase lysosomal enzyme in tissues of involved individuals. Delayed-onset PD is considered whenever symptoms onset start after one year of age. We present an update of the recommendations for the management of delayed-onset PD, taking as reference the guidelines from the Argentine Consensus for diagnosis, treatment and follow-up of PD published in 2013. Read More

Spinal Cord 2018 Nov 23;56(11):1084-1094. Epub 2018 Aug 23.

National Spinal Injuries Centre, Stoke Mandeville Hospital, Mandeville Road, Aylesbury, Bucks, HP21 8AL, UK.

Study Design: Cross-sectional phenomenological qualitative study.

Objectives: To investigate women's experience of sexuality after spinal cord injury (SCI) with a focus on rehabilitation and manging practical impact.

Setting: Women with SCI living in the community in United Kingdom (UK). Read More

Eur Respir J 2018 Sep 18;52(3). Epub 2018 Sep 18.

Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

Our objective was to quantify health service utilisation including monitoring and treatment of respiratory complications for adults with neuromuscular disease (NMD), identifying practice variation and adherence to guideline recommendations at a population level.We conducted a population-based longitudinal cohort study (2003-2015) of adults with NMD using hospital diagnostic and health insurance billing codes within administrative health databases.We identified 185 586 adults with NMD. Read More

Pediatr Pulmonol 2018 Oct 21;53(10):1378-1386. Epub 2018 Aug 21.

Sunnybrook Health Sciences Centre, Sunnybrook Research Institute and the Institute of Clinical Evaluative Sciences, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

Objectives: To quantify health service utilization including assessment, monitoring, and treatment of respiratory complications of children with neuromuscular disease (NMD), identifying practice variation and adherence to guideline recommendations at a population level.

Methods: North American population-based cohort study (2003-2015) of children with NMD using hospital diagnostic and physician billing codes within health administrative databases.

Results: We identified 18 163 children with NMD. Read More

BMC Public Health 2018 Aug 15;18(1):1014. Epub 2018 Aug 15.

Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

Background: Group-based transdiagnostic occupational rehabilitation programs including participants with mental and somatic disorders have emerged in clinical practice. Knowledge is sparse on subsequent participation in competitive work. This study aimed to investigate trajectories for (re)entry to work for predefined subgroups in a diagnostically heterogeneous sample of sick-listed participants after completing occupational rehabilitation. Read More

Expert Rev Neurother 2018 Sep 21;18(9):693-703. Epub 2018 Aug 21.

a Neuromuscular Center , San Camillo Hospital IRCCS , Venice , Italy.

Introduction: Limb-girdle muscular dystrophies (LGMDs) encompass a clinically heterogeneous group of rare, genetic progressive muscle disorders presenting with weakness and atrophy of predominant pelvic and shoulder muscles. The spectrum of disease severity ranges from severe childhood-onset muscular dystrophy to adult-onset dystrophy. Areas covered: The review presents an update of the clinical phenotypes and diagnostic options for LGMD including both dominant and recessive LGMD and consider their differential clinical and histopathological features. Read More

Medicine (Baltimore) 2018 Aug;97(31):e11761

Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daegu, Republic of Korea.

Background: Cervical radicular pain is a challenging medical problem in terms of therapeutic management. Recently, pulsed radiofrequency (PRF) stimulation on the dorsal root ganglion (DRG) has been used to control several types of chronic pain. However, its effect on cervical radicular pain is still not well studied. Read More

Medicine (Baltimore) 2018 Aug;97(31):e11658

Department of Neurology, The Fourth People's Hospital of Shaanxi, Xi'an, Shaanxi, China.

This pilot study retrospectively investigated the feasible effect and safety of neuromuscular electrical stimulation (NMES) for the management of neuropathic pain (NPP) caused by spinal cord injury (SCI).A total of 54 patient cases with NPP after SCI were included. Of these, 27 cases underwent carbamazepine plus NMES treatment, and were assigned to an NMES group; while the other 27 cases received carbamazepine only, and were assigned to a control group. Read More

Arq Neuropsiquiatr 2018 Jul;76(7):481-489

Associação Brasileira de Distrofia Muscular Viver Bem sem Limite, São Paulo SP, Brasil.

Significant advances in the understanding and management of Duchenne muscular dystrophy (DMD) have occurred since the publication of international guidelines for DMD care in 2010. Our objective was to provide an evidence-based national consensus statement for multidisciplinary care of DMD in Brazil. A combination of the Delphi technique with a systematic review of studies from 2010 to 2016 was employed to classify evidence levels and grade of recommendations for the guideline. Read More

Dev Med Child Neurol 2019 01 29;61(1):75-81. Epub 2018 Jul 29.

Child Health Evaluative Sciences Program, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada.

Aim: To develop a patient-reported outcome measure that comprehensively captures the health-related priorities of children with Duchenne muscular dystrophy (DMD).

Method: Children with DMD and their parents completed the iteratively revised versions of the Caregiver Priorities and Child Health Index of Life with Disabilities (CPCHILD), followed by a cognitive interview to develop a pilot version of a new measure. Multidisciplinary health care professionals completed an item-by-item analysis of the measure and a 14-item sensibility questionnaire. Read More

Degener Neurol Neuromuscul Dis 2017 26;7:79-93. Epub 2017 Jun 26.

Department of Internal Medicine, Carver College of Medicine,

Purpose: To investigate the effects of a multimodal intervention including a modified Paleolithic diet, nutritional supplements, stretching, strengthening exercises with electrical stimulation of trunk and lower limb muscles, meditation and massage on walking performance and balance of subjects with progressive multiple sclerosis (MS).

Materials And Methods: Twenty subjects with mean (standard deviation) age of 51.7 (6. Read More

Int J Technol Assess Health Care 2018 Jan 26;34(4):400-409. Epub 2018 Jul 26.

Department of Clinical Psychological Science,Maastricht University CAPHRI - School for Public Health and Primary Care, Department of Rehabilitation Medicine, Maastricht University.

Objectives: The aim of this study was to evaluate the cost-effectiveness of exposure in vivo (EXP, a cognitive-behavioral treatment targeting pain-related fear) in Complex Regional Pain Syndrome Type I (CRPS-I), as compared to pain-contingent physical therapy (PPT).

Methods: Data from a randomized controlled trial were used to compare the cost-effectiveness of EXP versus PPT from a societal perspective. Intervention costs, other healthcare costs, costs to patient and family, and productivity losses were included. Read More

Med Hypotheses 2018 Sep 20;118:55-58. Epub 2018 Jun 20.

Clinical Electromyography Laboratory, University Hospitals UZ Leuven, Herestraat 49, 3000 Leuven, Belgium.

Fibromyalgia (FM) exhibits characteristics of a neurological disorder, and similarities have been identified between FM and idiopathic intracranial hypertension (IICH). When intracranial pressure rises, the drainage of excess cerebrospinal fluid (CSF) through the subarachnoid space of the cranial and spinal nerves increases. Higher CSF pressure irritates nerve fibers inside nerve root sheaths and may consequently cause radicular pain, as was reported in patients with IICH. Read More

Med Hypotheses 2018 09 3;118:127. Epub 2018 Jul 3.

Department of Physical Medicine and Rehabilitation, Metropolitan Hospital Center, 1901 First Avenue, New York, NY 10029, USA. Electronic address:

Physiotherapy 2018 09 20;104(3):311-317. Epub 2018 Jun 20.

Department of Physical Therapy, Speech Therapy and Occupational Therapy, School of Medicine of the University of Sao Paulo, Sao Paulo, SP, Brazil.

Fibromyalgia is a rheumatic syndrome characterised by chronic widespread pain, often associated with fatigue, unrefreshed sleep and cognitive problems. Effective management of fibromyalgia requires a proactive approach in which the patient takes responsibility for self-care. The purpose of this research was to develop an application (app) for promoting self-care as a complementary Mobile Health resource to physical therapy in the management of fibromyalgia. Read More

Clin Exp Rheumatol 2018 Jul-Aug;36 Suppl 113(4):76-81. Epub 2018 Jun 7.

Department of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Objectives: To identify the clinical differences and mortality rate between adult and elderly onset systemic sclerosis (SSc).

Methods: We conducted a historical cohort study of SSc patients during January 2007-December 2011. The SSc patients were 60 and over classified as elderly onset SSc. Read More

J Int Med Res 2018 Aug 12;46(8):3394-3403. Epub 2018 Jul 12.

1 Orthopedic and Trauma Department, Veteran's Memorial Teaching Hospital, Medical University of Lodz, Lodz, Poland.

According to previously published papers, neurovascular injuries seem to be the most unfortunate complications after surgical procedures. In this report, we present our therapeutic approach to iatrogenic injury of the posterior tibial nerve that occurred during ankle arthroscopy in a 24-year-old patient. The outcome of the therapy was a full sensory return and partial motor return (S4 and M3 according to the Medical Research Council Grading System for Nerve Recovery). Read More

Trans R Soc Trop Med Hyg 2018 Jul;112(7):326-334

Hospital for Tropical Diseases, University College Hospital, London.

Background: Neurocysticercosis is the commonest infectious cause of epilepsy in endemic countries, and accounts for a greater number of cases worldwide than any other single pathology. Infection is associated with long-term exposure in low-income countries, although acquisition after travel has been recognized. The standard of care in the UK is inpatient treatment with anti-helminthic drugs and steroids. Read More

Pediatr Phys Ther 2018 07;30(3):164-175

Rehabilitation Services (Dr Heidenreich), Arkansas Children's Hospital, Little Rock, Arkansas; Division of Biokinesiology and Physical Therapy (Dr Sargent), Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, California; Norris Medical Library (Mr Johnson), University of Southern California, Los Angeles, California.

Purpose: To systematically review the recent evidence on physical therapy (PT) diagnosis, prognosis, and intervention of congenital muscular torticollis to inform the update to the PT management of congenital muscular torticollis evidence-based clinical practice guideline.

Methods: From 2012 to 2017, 7 databases were searched for studies that informed PT diagnosis, prognosis, or intervention of infants and children with congenital muscular torticollis. Studies were appraised for risk of bias and quality. Read More