Search Our Scientific Publications & Authors

Semin Neurol 2018 Dec 6;38(6):619-626. Epub 2018 Dec 6.

Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.

Posttraumatic headaches are among the most challenging complaints after mild traumatic brain injury (mTBI). They are a debilitating problem experienced by patients after TBI of all severities. Up to 90% of mild TBI patients experience headache, particularly if female and with a premorbid history of primary headache. Read More

Arch Oral Biol 2018 Nov 28;98:238-242. Epub 2018 Nov 28.

Kawasaki University of Medical Welfare, 288 Matsushima, Kurashiki, Okayama 701-0193, Japan. Electronic address:

Objective: The aim of the present study was to investigate whether anterior tongue muscle strengthening exercises can affect the strength of posterior tongue muscles.

Design: Eleven healthy subjects (20.6 ± 1. Read More

Gait Posture 2018 Nov 20;68:227-231. Epub 2018 Nov 20.

Monash University, School of Primary and Allied Health Care, Frankston, VIC, 3199, Australia; Peninsula Health, Allied Health, 4 Hastings Rd, Frankston, VIC, 3199, Australia.

Background: There remains a substantial lack of evidence to support the use of foot orthoses as a conservative treatment option for idiopathic toe walking (ITW). Encouraging heel contact during gait is one of the primary goals of most interventions in paediatric ITW.

Research Question: Does the combined treatment of high-top boots and orthoses increase the number of heel contacts during gait and change spatio-temporal gait parameters?

Methods: This within subject designed randomised controlled trial recruited fifteen children diagnosed with ITW (n = 10 males). Read More

Atherosclerosis 2018 Nov 23;280:147-154. Epub 2018 Nov 23.

Department of Anesthesiology, Shuan Ho Hospital, Taipei Medical University, New Taipei City, Taiwan; Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Department of Anesthesiology, Taipei Medical University Hospital, Taipei, Taiwan; Health Policy Research Center, Taipei Medical University Hospital, Taipei, Taiwan; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan. Electronic address:

Background And Aims: The risk of stroke in epileptic patients and the impact of epilepsy history on stroke patients' outcome have not been studied completely. Our purpose is to evaluate whether patients with epilepsy have increased risk of stroke or post-stroke mortality.

Methods: In Study I, we conducted a retrospective cohort study of 6746 patients with newly diagnosed epilepsy and 26,984 persons without epilepsy between 2000 and 2008, in the database of National Health Insurance in Taiwan. Read More

J Biomed Inform 2018 Dec 3. Epub 2018 Dec 3.

Department of Computer Science Sapienza University of Rome, Via Salaria 113, 00198, Rome, Italy. Electronic address:

Strokes, surgeries, or degenerative diseases can impair motor abilities and balance. Long-term rehabilitation is often the only way to recover, as completely as possible, these lost skills. To be effective, this type of rehabilitation should follow three main rules. Read More

Am J Med 2018 Dec 3. Epub 2018 Dec 3.

Department of Epidemiology, Center for Public Health, Medical University of Vienna, Kinderspitalgasse 15/1, 1090 Vienna, Austria; Department of Cancer Epidemiology and Prevention Research, Alberta Health Services, Holy Cross Centre, 2210-2nd Street SW, Box ACB, Calgary, AB, T2S 3C3, Canada; Preventive Oncology & Community Health Sciences, Cumming School of Medicine, University of Calgary, Hospital Drive NW, Calgary, Alberta, Canada. Electronic address:

Objective: Healthcare providers are encouraged to prescribe lifestyle modifications for preventing and managing obesity and associated chronic conditions. However, the pattern of lifestyle advice provision is unknown. We investigate the prevalence of advised lifestyle modification according to weight status and chronic conditions in a US nationally representative sample. Read More

Acta Ortop Mex 2018 May-Jun;32(3):163-166

Servicio de Cirugía Ortopédica y Traumatología, Hospital de Sabadell. Institut Universitari Parc Taulí Universitat Autònoma de Barcelona, España.

We present the case of an 81-year-old woman who was followed up by the Rheumatology Service for osteoporosis and treated with bisphosphonates for more than five years. She reported a fracture of the distal third of the contralateral femur by a low energy mechanism, treated with retrograde intramedullary nailing the previous year. She presented a clinic of cruralgia and left gonalgia, without previous trauma. Read More

Int J Oral Maxillofac Implants 2018 Dec 5. Epub 2018 Dec 5.

Purpose: The aim of this study was to examine the long-term results of implants in orbital reconstruction after exenteration.

Materials And Methods: From 1998 to 2012, patients undergoing implant-supported rehabilitation after subtotal or total exenteration due to a tumor were included in a retrospective study. All the patients were evaluated for soft tissue reconstruction, irradiation, complications, abutments, hygiene index, implant mobility, and long-term success. Read More

PLoS One 2018 6;13(12):e0208127. Epub 2018 Dec 6.

Queen Margaret University, Centre of Health, Activity and Rehabilitation Research, Edinburgh, United Kingdom.

Background: Stage 5 chronic kidney disease patients on haemodialysis (HD) often present with dizziness and pre-syncopal events as a result of the combined effect of HD therapy and cardiovascular disease. The dysregulation of blood pressure (BP) during orthostasis may be implicated in the aetiology of falls in these patients. Therefore, we explored the relationship between baroreflex function, the haemodynamic responses to a passive orthostatic challenge, and falls in HD patients. Read More

Aging Ment Health 2018 Dec 6:1-9. Epub 2018 Dec 6.

b Faculty of Health Sciences , Western University , London , Canada.

Objectives: The study used data from the Canadian Longitudinal Study on Aging to investigate the relationships among social support (measured as affectionate support, emotional/informational support, positive social interaction, tangible support), social participation and depression in caregivers and non-caregivers.

Method: Hierarchical multiple regression was used to investigate relationships among social support, social participation, and depression. Analyses of variance were used to examine differences in the means of social support, social participation, and depression between the two participant groups. Read More

Clin Anat 2018 Dec 6. Epub 2018 Dec 6.

Department of Clinical Anatomy, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan.

Introduction: To improve the management outcomes and diagnostic accuracy of the ulnar collateral ligament (UCL) injury, the anatomy of the medial side of the elbow joint is necessary to be understood in terms of the periarticular surroundings rather than the specific ligaments. The aim of this study was to anatomically clarify the medial side of the elbow joint in terms of the tendinous structures and joint capsule.

Materials And Methods: We conducted a descriptive anatomical study of 23 embalmed cadaveric elbows. Read More

Clin Oral Implants Res 2018 Dec 6. Epub 2018 Dec 6.

Department of Oral Surgery and Implant Dentistry, Faculdade de Medicina Dentária da Universidade de Lisboa, Portugal.

Objectives: To evaluate the performance of two types of zirconia frameworks.

Material And Methods: From 2014 to 2016, in a prospective clinical trial 150 patients were rehabilitated with 83 and 110 implant-supported, screw-retained, full-arch ceramic-veneered zirconia (PVZ) rehabilitations and monolithic zirconia with porcelain veneering limited to buccal (MZ) rehabilitations, respectively. Patients were consecutively enlisted according to pre-defined inclusion criteria and evaluated on 4 months intervals. Read More

Ugeskr Laeger 2018 Dec;180(49)

Bronchiectasis is characterised by chronic cough, airway inflammation, infection and bronchial dilatation. The disease may lead to impaired lung function and premature death. An underlying inflammatory disease or immunodeficiency may be present, but 40% of the cases are idiopathic. Read More

J Neurotrauma 2018 Dec 6. Epub 2018 Dec 6.

University of Pittsburgh, Neurosurgery , 3434 Fifth Ave , Pittsburgh, Pennsylvania, United States , PA ;

New neuroprotective therapies for severe traumatic brain injury (TBI) have not translated from pre-clinical to clinical success. Numerous explanations have been suggested in both the pre-clinical and clinical arenas. Coverage of TBI in the lay press has reinvigorated interest creating a golden age of TBI research with innovative strategies to circumvent roadblocks. Read More

J Esthet Restor Dent 2018 Dec 6. Epub 2018 Dec 6.

Q LAB, Perth, Western Australia, Australia.

Objective: To report an alternative clinical and laboratory protocol for same-day implant fixed full-arch provisional rehabilitation that may overcome limitations associated with traditional immediate provisional denture conversion rehabilitation protocols.

Clinical Considerations: The traditional denture conversion fabrication method of an immediate full-arch fixed provisional involves the conversion of a complete denture into a provisional fixed implant-support prosthesis. The conversion technique has several shortcomings which compromise structural integrity, longevity, ease of modification, and the need for a silicone impression. Read More

Int J Eat Disord 2018 Dec 6. Epub 2018 Dec 6.

Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.

Objective: An association between bulimia nervosa (BN) and prolonged corrected QT interval (QTc) in the electrocardiogram has been suggested, but results of previous studies are conflicting, and the risk of cardiac events in patients with BN has yet to be investigated.

Method: We estimated mean QTc interval and relative risk of borderline (QTc >440 ms) and prolonged QTc (QTc >460 ms) between adult women with BN (N = 531) and healthy controls (N = 123). In follow-up analyses, we investigated the risk of a primary endpoint (syncope, ventricular tachycardia, and cardiac arrest) and all-cause mortality in patients with BN (N = 702) compared with a population-based cohort derived from the Danish Civil Register (N = 7,020). Read More

Environ Eng Sci 2018 Dec 30;35(12):1394. Epub 2018 Nov 30.

[This retracts the article DOI: 10.1089/ees.2006. Read More

Acta Bioeng Biomech 2018 ;20(4):107-113

Department of Physical Medicine, Medical University of Lodz, Łódź, Poland.

Purpose: Upper limb impairment in the early phase of brain stroke is one of the key problems in rehabilitation. An estimation of muscle force can be a helpful factor for functional improvement after a stroke. The primary goals of this study were to determine the muscles with the lowest force in the affected (A) and non-affected (non-A) upper limb. Read More

Acta Bioeng Biomech 2018 ;20(4):89-100

Division of Sports Medicine, Wrocław Medical University, Wrocław, Poland.

Purpose: The observational study evaluated isokinetic parameters in patients at eight months after anterior cruciate ligament reconstruction (ACLR) utilizing semitendinosus and gracilis tendons autograft, with two different modes of physiotherapy, and investigated whether analysed parameters were affected by the postoperative physiotherapy supervision duration.

Methods: Strict exclusion criteria were employed on a group of 259 ACL-reconstructed patients to identify two groups of males preoperatively well trained and frequently participating in sports, with different durations of postoperative physiotherapy supervision: Group I (n = 18; x = 27.67 weeks) and Group II (n = 20; x = 10. Read More

Acta Bioeng Biomech 2018 ;20(4):43-49

Józef Piłsudski University of Physical Education in Warsaw, Faculty of Rehabilitation, Warsaw, Poland.

Purpose: Simulating the complexities of lower limb motion can be useful for orthosis or rehabilitation planning. The aim of this study was to develop an artificial neural network (ANN) able to accurately simulate the changes in the angle of the ankle, knee and hip joints during the gait cycle, then to use it to simulate the impact of a restricted range of ankle and hip joint angle changes on the progres- sion of the knee joint angle.

Methods: Thirty four young healthy students participated in the study. Read More

Int Psychogeriatr 2018 Dec 6:1-17. Epub 2018 Dec 6.

Health & Rehabilitation Sciences,University of Western Ontario,London, ON,Canada.

ABSTRACTBackground:People with dementia fall twice as often and have more serious fall-related injuries than healthy older adults. While gait impairment as a generic term is understood as a fall risk factor in this population, a clear elaboration of the specific components of gait that are associated with falls risk is needed for knowledge translation to clinical practice and the development of fall prevention strategies for people with dementia.

Objective: To review gait parameters and characteristics associated with falls in people with dementia. Read More

Int J Artif Organs 2018 Dec 6:391398818815492. Epub 2018 Dec 6.

1 Schüchtermann-Klinik Bad Rothenfelde, Bad Rothenfelde, Germany.

Following implantation of a left ventricular assist device, the build-up and long-term maintenance of adequate exercise capacity and functional performance become crucial. The aim of this study was to observe the development of exercise-related values at different times, as well as to detect possible influencing factors. We performed a prospective single-centre study: 10 patients (63 years, 100% male, body mass index = 27. Read More

J Cosmet Dermatol 2018 Dec 5. Epub 2018 Dec 5.

Department of Aesthetic Medicine, Medical University of Bialystok, Bialystok, Poland.

Background: Aesthetic surgery procedures such as lip augmentation, eyelid correction, face-lifting, or Botox treatment for lines and wrinkles are an important part of cosmetic surgery.

Objectives: The aim of the study was to estimate improvement in appearance following plastic surgery using modern collective intelligence methods of validation.

Methods: A total of 108 photographs showing 54 patients prior to and following cosmetic surgery were downloaded from Internet web presentations of several unnamed plastic surgeons. Read More

Health Expect 2018 Dec 5. Epub 2018 Dec 5.

Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Background: The published literature demands examples of health-care systems designed with the active engagement of patients to explore the application of this complex phenomenon in practice.

Methods: This case study explored how the voice of patients was incorporated into the process of redesigning an element of the health-care system, a centralized system for intake of referrals from primary care to rheumatologists for patients with suspected rheumatoid arthritis (RA)-centralized intake. The phenomenon of patient engagement using "patient and community engagement researchers" (PaCERs) in research and the process of redesigning centralized intake were selected as the case. Read More

Clin Oral Implants Res 2018 Dec 5. Epub 2018 Dec 5.

School of Dentistry, Federal University of Goias, Goiania, Goias, Brazil.

Objective: This study aimed to explore the perceptions and long-term experiences of edentulous patients rehabilitated with single-implant mandibular overdentures (SIMO).

Methods: Thirteen participants, mean age 65.7 years, 69. Read More

Contact Dermatitis 2018 Dec 5. Epub 2018 Dec 5.

University of Groningen, University Medical Center Groningen, Department of Dermatology, The Netherlands.

Background: Analyses of the European Surveillance System on Contact Allergies (ESSCA) database have focused primarily on prevalence of contact allergies to the European baseline series; overall and in subgroups of patients. However, affected body sites have hitherto not been addressed.

Objective: To determine prevalence of contact allergies for distinct body sites in patients with allergic contact dermatitis (ACD). Read More

Brain Imaging Behav 2018 Dec 5. Epub 2018 Dec 5.

Department of Psychology, University of Alabama at Birmingham, CIRC 235H, 1720 2nd Avenue South, Birmingham, AL, 35294, USA.

The prefrontal cortex, amygdala, hippocampus, and hypothalamus are important components of the neural network that mediates the healthy learning, expression, and regulation of emotion. These brain regions are connected by white matter pathways that include the cingulum bundle, uncinate fasciculus, and fornix/stria terminalis. Individuals with trauma and stress-related disorders show dysfunction of the cognitive-affective processes supported by the brain regions these white matter tracts connect. Read More

J Ultrasound 2018 Dec 5. Epub 2018 Dec 5.

Department of Physical Medicine and Rehabilitation, Sanggye Paik Hospital, Inje University College of Medicine, Sanggye 7 dong 761-7, Nowon-gu, 139-707, Seoul, South Korea.

Purpose: Recent studies have compared the therapeutic efficacy and safety of the procedure using ultrasound and fluoroscopy. However, there are no published studies comparing the therapeutic efficacy and safety of fluoroscopy (FL)-guided cervical interlaminar epidural steroid injection (CIESI) with that of ultrasound (US)-guided selective nerve root block (SNRB). This study aimed to compare the mid-term effects and advantages of US-guided SNRB with FL-guided CIESI for radicular pain in the lower cervical spine through assessment of pain relief and functional improvement. Read More

Chin J Integr Med 2018 Dec 5. Epub 2018 Dec 5.

Department of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, China.

Objective: To evaluate the involvement of different CD4 T cell subtypes in the anti-asthmatic effects of acupuncture in asthmatic mice.

Methods: BALB/c mice were challenged by ovalbumin (OVA) for the establishment of experimental asthma model. Mice were divided into 4 groups by a random number table including the normal control, asthma model, acupuncture and sham acupuncture groups (14 per group). Read More

Chin J Integr Med 2018 Dec 5. Epub 2018 Dec 5.

Collaborative Innovation Center for Rehabilitation Technology, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.

Objective: To evaluate the effect of tai chi exercise on cardiac and static lung function for older community-dwelling adults at risk of ischemic stroke.

Methods: A total of 170 older community-dwelling adults (aged 55-75 years old) at risk of ischemic stroke were allocated to either tai chi training group (85 cases, five 60-min sessions of tai chi training per week for 12 weeks) or control group (85 cases, usual pbysical activity for 12 weeks) using a computer-generated randomization. The echocardiographic parameters of cardiac structure, cardiac function and static lung function were measured at baseline, after 12 weeks of intervention and additional 12-week follow-up period by a blinded professional staffmember using a color Doppler ultrasound imaging device or a cardiopulmonary function instrument. Read More

Int J Comput Assist Radiol Surg 2018 Dec 5. Epub 2018 Dec 5.

Department of Biomedical Engineering, University of Alberta, 1098 Research Transition Facility, 8308-114 Street, Edmonton, AB, T6G 2V2, Canada.

Purpose: Determine the positional, rotational and reconstruction accuracy of a 3D ultrasound system to be used for image registration in navigation surgery.

Methods: A custom 3D ultrasound for spinal surgery image registration was developed using Optitrack Prime 13-W motion capture cameras and a SonixTablet Ultrasound System. Temporal and spatial calibration was completed to account for time latencies between the two systems and to ensure accurate motion tracking of the ultrasound transducer. Read More

Community Ment Health J 2018 Dec 5. Epub 2018 Dec 5.

Kyambogo University, Kampala, Uganda.

The current study examined the impact of sedentary behaviour (SB) on quality of life (QoL) in people with psychotic disorders. Thirty-six Ugandan women (mean age = 33.9 ± 8. Read More

Arch Orthop Trauma Surg 2018 Dec 5. Epub 2018 Dec 5.

Department of Orthopaedic and Trauma Surgery, Robert-Bosch-Krankenhaus Stuttgart, Auerbachstrasse 110, 70376, Stuttgart, Germany.

Objective: The objective of the current study was to evaluate the effect of a quality management system on treatment and care delivery of proximal femoral fractures. Specifically, our hypothesis was that the "plan-do-check-act (PDCA)" philosophy of the ISO 9001 quality management system results in a continuous improvement process.

Methods: 1015 proximal femoral fractures were prospectively included into a hip fracture database over a 5-year period, after a restructuring process with implementation of clinical pathways and standard operation procedures. Read More

Biomed Res Int 2018 5;2018:5786089. Epub 2018 Nov 5.

Department of Orthopedics, First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang, Ouhai, Wenzhou, Zhejiang 325000, China.

Introduction: Internal fixation with volar locking plate (VLP) was widely adopted as a first-line choice in treatment of distal radius fracture (DRF).

Methods: Total 315 patients with distal radius fracture receiving VLP fixation were included for analysis in this study. The rehabilitation protocol was started immediately after surgery for all patients. Read More

Biomed Res Int 2018 4;2018:2439312. Epub 2018 Nov 4.

Department of Physical Therapy, College of Health Science, Sahmyook University, Republic of Korea.

Background: The monitoring and rehabilitation of pulmonary function can be immensely important for long-term performance of daily life activities in stroke patients. In recent times, smartphone game-based assessment (SGA) has been gaining in popularity as an alternative to laboratory assessments. Hence, the aims of this study were (1) to quantify the reliability and validity of SGA for pulmonary function and (2) to assess the validity of SGA in comparison to spirometry. Read More

ERJ Open Res 2018 Oct 3;4(4). Epub 2018 Dec 3.

Dept of Research and Education, CIRO+, Center of Expertise for Chronic Organ Failure, Horn, The Netherlands.

http://ow.ly/2HER30mxLLj. Read More

MethodsX 2018 22;5:1521-1527. Epub 2018 Nov 22.

Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China.

A methodology for wound state sensing in terms of its colonization with pathogenic bacteria such as or has been developed. Here we report polydiacetylene (PDA) liposomes containing self-quenched carboxyfluorescein dye are only sensitive to toxins/enzymes secreted by Pathogenic bacteria but not by non-pathogenic species of (DH5α). The basis of the detection assay is that at high concentration, carboxyfluorescein is non-fluorescent. Read More

IEEE J Transl Eng Health Med 2018 18;6:2101009. Epub 2018 Oct 18.

Industrial Design DepartmentEindhoven University of Technology5612AZEindhovenThe Netherlands.

The objective is to evaluate to which extent that a garment equipped with sensors that can support posture monitoring can be used in upper extremity rehabilitation training of stroke patients. Seventeen stroke survivors (mean age: 55 years old, SD =13.5) were recruited in three hospitals in Shanghai. Read More

Rehabil Res Pract 2018 4;2018:6183654. Epub 2018 Nov 4.

State University of Piauí, Department of Physical Therapy, Teresina, PI, Brazil.

Background/aim: To evaluate, in this pilot study, the effects of the mirror (MT) and vibration therapies (VT) on the functionality of hemiparesis patients after stroke.

Materials And Methods: Twenty-one individuals after stroke with upper limb hemiparesis were randomized into control group (CG), Mirror Therapy Group (MTG), and Vibration Therapy Group (VTG). The functionality was evaluated before and after 12 sessions with three tests (i) Mobility Index Rivermead, (ii) Motor Function Wolf Test (time, functional ability), and (iii) Jebsen Taylor Test. Read More

Pilot Feasibility Stud 2018 29;4:181. Epub 2018 Nov 29.

1Department of Physiotherapy/Community Services, Western Health, 176 Furlong Road, St Albans, Victoria 3021 Australia.

Background: Multimorbidity (the co-existence of two or more chronic conditions in an individual) is a growing healthcare burden internationally; however, healthcare and disease management, including rehabilitation, is often delivered in single-disease siloes. The aims of this study were to (1) evaluate the safety and feasibility of multimorbidity rehabilitation compared to a disease-specific rehabilitation program in people with multimorbidity and (2) gather preliminary data regarding clinical outcomes and resource utilization to inform the design of future trials.

Methods: A pilot feasibility randomized controlled trial with concealed allocation, assessor blinding, and intention-to-treat analysis. Read More

Pilot Feasibility Stud 2018 29;4:179. Epub 2018 Nov 29.

7Department of Physical Therapy, University of Toronto, Toronto, Ontario Canada.

Background: Limited outdoor walking is a marker of frailty and a risk factor for decline in mobility and self-care functioning, social isolation, and reduced health-related quality of life (HRQL). Objectives were to evaluate the safety, feasibility, and preliminary effect of a supervised outdoor walking group and interactive workshop compared to the workshop alone in increasing outdoor walking activity and identify an optimal method for estimating outdoor walking activity among older adults who infrequently walk outdoors.

Methods: A pilot 2-parallel-group randomized controlled trial was conducted. Read More

Pilot Feasibility Stud 2018 28;4:178. Epub 2018 Nov 28.

2School of Health Sciences, University of KwaZulu-Natal, Private Bag X54001, Durban, 4000 South Africa.

Background: A significant number of children experience disabilities as a result of living with HIV, including those on antiretroviral therapy (ART). Current paediatric HIV care does not prioritise rehabilitation. Furthermore, little attention is paid to cognitive development and educational needs, thereby placing the future of these children at risk. Read More

Breathe (Sheff) 2018 Dec;14(4):317-318

Early Life Origins of Chronic Lung Disease, Research Center Borstel, Leibniz Lung Center, Member of the German Center for Lung Research (DZL), Borstel, Germany.


http://ow.ly/n0PC30lp2V3. Read More

Front Neurol 2018 21;9:982. Epub 2018 Nov 21.

Department of Neurology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

A combined approach of behavioral characteristics and network properties was applied to explore the effect of repetitive transcranial magnetic stimulation (rTMS) on disorders of consciousness (DOC) and to observe changes in brain network connections before and after the stimulation. A total of 7 DOC patients and 11 healthy controls were enrolled. The study was designed as a randomized, sham-controlled study. Read More

Front Neurol 2018 21;9:968. Epub 2018 Nov 21.

National Research Centre for the Working Environment, Copenhagen, Denmark.

While acute stress and pain are part of our inherent survival mechanisms, persistent stress and pain can negatively impact health and well-being. This may also lead to poor sleep and thus a lack of recovery. This study investigated the influence of stress and musculoskeletal pain on sleep quality. Read More

Case Rep Neurol 2018 Sep-Dec;10(3):309-313. Epub 2018 Nov 8.

Internal Medicine, Mount Carmel West Hospital, Columbus, Ohio, USA.

Thiamine deficiency is a condition characterized by several different presentations, but one of the most devastating is dry beriberi. It is associated with polyneuropathy and muscle weakness which typically affects the lower extremities and progressively involves the upper extremities. This case outlines a case of a 41-year-old man that presented to the hospital with diffuse weakness and decreased sensation in his legs and hands over a 3-day period. Read More

Cancer Manag Res 2018 9;10:5591-5603. Epub 2018 Nov 9.

Department of Children's Rehabilitation, Shangqiu First People's Hospital of Henan, Shangqiu, Henan, China.

Background: SIRT4 is a member of the sirtuin family of nicotinamide adenine dinucleotide-dependent enzymes located in the mitochondria, and is involved in regulating energy metabolism, stress response, and cellular lifespan in mammalian cells. However, its function in human neuroblastoma (NB) remains unexplored.

Methods: Expression of SIRT4 in 158 pairs of human NB tumor tissues and adjacent normal tissues collected from March 2009 to October 2012 was analyzed by immunohistochemistry, Western blotting, and real-time fluorescence quantitative PCR. Read More

J Pain Res 2018 13;11:2859-2866. Epub 2018 Nov 13.

Sannoh Orthopedic Clinic, Pain Clinic and Rehabilitation for Musculoskeletal Disorders, Sannoh Hospital, Chiba, Japan,

Background: Complex regional pain syndrome type I (CRPS I) in children is a serious condition disrupting the family and school life of patients with the condition after it fully develops. It has been emphasized that early diagnosis is closely associated with earlier reduction of pain leading to preferable outcomes.

Objectives: To report a case of acute CRPS I in a boy who was found to develop this condition by a routine visual analog scale (VAS) pain monitoring and who recovered from CRPS I at an early phase by prompt pharmacological, physical, and educational therapies. Read More

J Pain Res 2018 8;11:2781-2789. Epub 2018 Nov 8.

Department of Sport Sciences, Payame Noor University, Tehran, Iran.

Introduction: The aim of this survey was to examine the effect of adding electromyographic biofeedback (EMGBF) to isometric exercise, on pain, function, thickness, and maximal electrical activity in isometric contraction of the vastus medialis oblique (VMO) muscle in patients with knee osteoarthritis (OA).

Methods: In this clinical trial, 46 patients with a diagnosis of knee OA were recruited and assigned to two groups. The case group consisted of 23 patients with EMGBF-associated exercise, and the control group was made up of 23 patients with only isometric exercise. Read More