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Cureus 2022 May 22;14(5):e25227. Epub 2022 May 22.

Anaesthesiology, Uttar Pradesh University of Medical Sciences, Etawah, IND.

Introduction: Ultrasound-guided erector spinae plane (ESP) block has emerged as an effective and safe analgesic regional technique and it also provides visceral pain relief. Our aim was to compare the analgesic efficacy of ESP block over transversus abdominis plane (TAP) block under ultrasound guidance following a total abdominal hysterectomy.

Methods: This was a prospective, randomized, comparative study. Read More

J Clin Med 2022 Jun 13;11(12). Epub 2022 Jun 13.

Department of Trauma Nursing, Ajou University School of Medicine, Ajou University Hospital, Suwon 16499, Korea.

Perioperative cerebral hypoperfusion/ischemia is considered to play a pivotal role in the development of secondary traumatic brain injury (TBI). This prospective randomized, double-blind, controlled study investigated whether magnesium sulfate (MgSO) infusion was associated with neuroprotection in maintaining regional cerebral oxygen saturation (rSO) values in patients with mild TBI undergoing general anesthesia. Immediately after intubation, we randomly assigned patients with TBI to receive either intravenous MgSO (30 mg/kg for 10 min, followed by a continuous infusion of 15 mg/kg/h) or a placebo (saline) during surgery. Read More

Anasthesiol Intensivmed Notfallmed Schmerzther 2022 Jun 21;57(6):417-427. Epub 2022 Jun 21.

Perioperative analgesia plays an important role in thoracic surgery, regarding not only patient satisfaction, but also in preventing postoperative complications such as pneumonia. Ultrasound-guided thoracic wall blocks close the gap between opiate based and neuraxial pain management concepts.The following article explores the different ultrasound-guided approaches to anesthetize the thoracic wall, ranging from the ventral blocks such as parasternal or PECS I/II, followed by the lateral blocks (i. Read More

BJU Int 2022 Jun 21. Epub 2022 Jun 21.

Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Objectives: To prospectively compare robotically administered transperitoneal transversus abdominis plane to ultrasound-guided TAP (UTAP) to local anesthesia (LA) for pain control and narcotic use in robotic prostatectomy (RP) and robotic partial nephrectomy (RPN) patients.

Subjects/patients And Methods: Patients undergoing RP or RPN were randomized in a single blind 2:2:1 fashion to RTAP:UTAP:LA, with the study powered to evaluate superiority of UTAP to LA and non-inferiority of RTAP to UTAP. We compared time to deliver the block, operating room time, postoperative pain scores using the visual analog scale (VAS), and intraoperative and postoperative analgesia consumption. Read More

Trials 2022 Jun 20;23(1):516. Epub 2022 Jun 20.

Institution for Clinical Sciences, Karolinska Institutet at Danderyds Hospital, Stockholm, Sweden.

Background: Multimodal analgesia that provides optimal pain treatment with minimal side effects is important for optimal recovery after open cardiac surgery. Regional anaesthesia can be used to block noxious nerve signals. Because sternotomy causes considerable pain that lasts several days, a continuous nerve block is advantageous. Read More

Pan Afr Med J 2022 21;41:230. Epub 2022 Mar 21.

Service d'Anesthésie-Réanimation Chirurgicale, Centre Hospitalier Universitaire Habib Bourguiba Sfax, Sfax, Tunisie.

Introduction: post-operative laryngeal pain (POLP) is frequent and embarrassing. The purpose of this study is to assess the efficacy of endotracheal tube balloon (ETB) inflation with alkalinized lidocaine in the prevention of the POLP.

Methods: we conducted a prospective, single-center, double-blind, randomized study including patients undergoing general anesthesia with tracheal intubation (OTI) with an expected duration of less than 240 min. Read More

BMC Anesthesiol 2022 Jun 18;22(1):189. Epub 2022 Jun 18.

Department of anaesthesia, critical care and pain management, Faculty of Medicine, Suez Canal University, Ard Elgameiat, Ismailia, Egypt.

Background: Pain control following breast surgery is of utmost importance in order to reduce the chance of chronic pain development, and facilitate early rehabilitation. The erector spinae plane block (ESPB) is a recently developed regional anaesthesia procedure successfully used for different types of surgical procedures including thoracic and abdominal surgeries.

Methods: A double-blind, randomized, controlled trial was conducted on 90 patients who were scheduled for modified radical mastectomy (MRM). Read More

Contrast Media Mol Imaging 2022 3;2022:1703250. Epub 2022 Jun 3.

Department of Outpatient, Harbin Red Cross Central Hospital, Harbin 150076, Heilongjiang, China.

The objective of this research was to explore the effect of perioperative anesthesia management for patients based on the concept of enhanced recovery after surgery (ERAS) and the application value of the computed tomography (CT) localization method in lumbar spinal nerve anesthesia, reducing the damage caused by anesthesia. One hundred and twenty patients who underwent the lumbar spinal anesthesia in lower limb surgery were selected as the research subjects. According to puncture positioning and nursing intention, the patients were classified into the control group with 30 patients (method of anatomical landmarks), CT group with 50 patients (the CT localization), and ERAS group with 40 patients (the CT localization and the ERAS management). Read More

Anesth Analg 2022 Jul 16;135(1):e7-e8. Epub 2022 Jun 16.

Department of Anesthesiology, The Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, China,

Acta Med Acad 2022 Apr;51(1):14-20

Department of Orthopedic Surgery, University Hospital of Heraklion, Greece.

Objectives: Total Knee Replacement Surgery (TKR) is one of the most common elective orthopedic operations. Postoperative pain after total knee replacement, remains a challenge. In this retrospective observational study, we evaluated the effectiveness of 3-in-1 nerve block in patients after total knee arthroplasty compared to standard opioid treatment, and we state the reasons why this approach should still be considered. Read More

Transl Pediatr 2022 May;11(5):706-714

Department of Anesthesiology, Tianjin Children's Hospital, Tianjin, China.

Background: Pediatric patients often experience severe pain after thoracic surgery, especially in the early postoperative period. Recently, the focus has been on regional analgesia with the introduction of ultrasound-guided erector spinae plane blocks. We assumed that preoperative erector spinae plane block (ESPB) in children undergoing video-assisted thoracoscopic surgery (VATS) would reduce the consumption of perioperative opioids. Read More

Spine J 2022 Jun 4. Epub 2022 Jun 4.

Pain Management Research Unit, Department of Anesthesiology, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University.

Background Context: Length of hospital stay (LOS) is an important concern in all types of surgery, and the enhanced recovery after surgery (ERAS) protocol has been developed to improve perioperative management and outcomes, which require multidisciplinary management. In terms of pain control, intraoperative regional anesthesia and postoperative opioid-sparing analgesia are recommended. For open spine surgery, we aimed to combine thoracic epidural analgesia to reduce pain and opioid-related side effects, thereby hastening recovery. Read More

BMC Anesthesiol 2022 Jun 6;22(1):175. Epub 2022 Jun 6.

Department of Anesthesiology, The First Central Hospital of Baoding, Northern Greatwall Street 320#, Baoding, 071000, Hebei, China.

Background: The optimal analgesia for total knee arthroplasty (TKA) requires excellent analgesia while preserving muscle strength. This study aimed to determine the hypothesis that continuous adductor canal block (CACB) combined with the distal interspace between the popliteal artery and the posterior capsule of the knee (IPACK) block could effectively alleviate the pain of the posterior knee, decrease opioids consumption, and promote early recovery and discharge.

Methods: Patients undergoing unilateral, primary TKA were allocated into group CACB+SHAM (receiving CACB plus sham block) or group CACB+IPACK (receiving CACB plus IPACK block). Read More

Int J Surg 2022 Jul 1;103:106689. Epub 2022 Jun 1.

Department of Cardio-Thoracic Surgery, Chengdu Second People's Hospital, Chengdu, Sichuan, 610017, China. Electronic address:

Objective: To compare the analgesic efficacy and feasibility of erector spinae plane block (ESPB) with non-block care or other blocks in patients undergoing liver surgery.

Method: A meta-analysis of randomized controlled trials (RCTs) that compared ESPB to non-block care or local infiltration analgesia (LIA), intrathecal morphine (ITM) and quadratus lumborum block (QLB) for postoperative analgesia in liver surgery patients.

Results: Six RCTs containing 392 patients were included. Read More

Int J Surg 2022 06 26;102:106683. Epub 2022 May 26.

Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China. Electronic address:

Comput Math Methods Med 2022 17;2022:1944659. Epub 2022 May 17.

Department of Anesthesiology, Lishui Municipal Central Hospital, Lishui, Zhejiang 323000, China.

Objective: To investigate the effects of ultrasound-guided fascia iliac compartment block (FICB) on patients' postoperative pain and inflammatory factors as well as nucleotide-binding domain and leucine-rich repeat (NLR) family, pyrin domain-containing 3 (NLRP3) in femoral intertrochanteric fracture.

Methods: This single-blind randomized controlled study included 231 patients with femoral intertrochanteric fracture treated in our hospital from January 2017 to December 2020. All patients were randomized into two groups, the FICB group ( = 116) and the general anesthesia group (control group, = 115). Read More

BMC Anesthesiol 2022 May 24;22(1):159. Epub 2022 May 24.

Department of Anesthesiology and Critical Care Medicine, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden, Fetscherstr 74, 01307, Dresden, Germany.

Background: Dislocation of catheters within the tissue is a challenge in continuous regional anesthesia. A novel self-coiling catheter design is available and has demonstrated a lower dislocation rate in a cadaver model. The dislocation rate and effect on postoperative pain of these catheters in vivo has yet to be determined and were the subjects of this investigation. Read More

Biomed Res Int 2022 14;2022:1681803. Epub 2022 May 14.

Department of Anesthesiology, Chongqing University Jiangjin Hospital, School of Medicine, Chongqing University, Chongqing, China.

Objective: To evaluate the anesthetic effect and safety of dexmedetomidine in cesarean section.

Methods: The Cochrane Library, EMBASE, and PubMed databases (established until September 2020) were searched by computer. Two authors independently screened and extracted literature related to the application of dexmedetomidine in the cesarean section according to inclusion and exclusion criteria. Read More

Pain Ther 2022 May 23. Epub 2022 May 23.

Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, No. 134, Dongjie, Fuzhou, 350001, Fujian, China.

Background: Erector spinae plane block, a novel ultrasound-guided fascial plane block, has become popular for perioperative pain management. This randomized controlled trial tested the hypothesis that preoperative bilateral erector spinae plane block improves the quality of recovery in patients undergoing posterior lumbar interbody fusion.

Methods: Eighty-four patients scheduled for elective posterior lumbar interbody fusion were enrolled. Read More

J Orthop Surg Res 2022 May 19;17(1):282. Epub 2022 May 19.

Department of Orthopedics, Chongqing General Hospital, Chongqing, No.118, Xingguang Avenue, Liangjiang New Area, Chongqing, 401147, People's Republic of China.

Background: Quadratus lumborum block is a truncal block with several technique variations. It has been reported as providing effective analgesia for postoperative pain. The aim of this study is to determine the efficacy of the QL block in providing postoperative analgesia for hip surgery when compared with placebo or no block or other analgesic techniques. Read More

BMC Musculoskelet Disord 2022 May 19;23(1):468. Epub 2022 May 19.

Department of Orthopedics, West China Hospital/West China School of Medicine, Sichuan University, 37# Wuhou Guoxue road, Chengdu, 610041, China.

Background: Local infiltration analgesia (LIA) and adductor canal block (ACB) provide postoperative analgesia for total knee arthroplasty (TKA). ACB blocks the saphenous nerve and has smaller impacts on quadriceps muscle weakness. ACB theoretically does not have enough analgesic effects on posterior sensory nerves. Read More

Korean J Anesthesiol 2022 May 18. Epub 2022 May 18.

Department of anesthesia, surgical ICU, and pain management, faculty of medicine, Cairo University, Cairo, Egypt.

Background: Overweight and obesity present a rising public health problem. Bariatric surgeries are one modality of weight reduction. Pain after surgery can increase the length of hospital stay, with all the associated consequences especially in such vulnerable population. Read More

Front Med (Lausanne) 2022 26;9:862309. Epub 2022 Apr 26.

Pediatric Hematology/Oncology, Medical University of South Carolina, Charleston, SC, United States.

Purpose: Bone marrow harvesting is associated with significant postoperative pain that may have potential negative consequences for the patient and health care system. In the current absence of uniform guidelines, there exists considerable variability amongst providers with respect to perioperative analgesia, especially opioid administration. In this initiative, we explored the potential for preoperative bilateral quadratus lumborum blocks in combination with a standardized perioperative analgesic protocol to manage pain with the goal of reducing perioperative narcotic usage and thereby improving opioid stewardship. Read More

BMC Anesthesiol 2022 May 12;22(1):142. Epub 2022 May 12.

Department of Anesthesiology and Reanimation, School of Medicine, Istanbul Medipol University, Istanbul, Turkey.

Background: Interscalene brachial plexus block (ISB) is the gold standard method used for postoperative analgesia after arthroscopic shoulder surgery. Ultrasound guided erector spinae plane block (ESPB) is an interfascial plane block. The aim of this study is to compare the analgesic efficacy of ESPB and ISB after shoulder arthroscopy. Read More

Spine J 2022 May 6. Epub 2022 May 6.

Integrated Anesthesia Associates, Hartford, CT, USA.

Background Context: Anterior lumbar interbody fusion (ALIF) is a well-established technique to address numerous pathological conditions of the spine and to restore sagittal spine balance. Improving patient comfort and reducing opioid consumption following lumbar fusions is a significant goal for spine surgeons. Therefore, there is a growing need to explore multimodal options for pain management post-surgery. Read More

Spine J 2022 05;22(5):892-893

Department of Spine Surgery, Ganga Medical Centre and Hospitals Pvt. Ltd., Mettupalayam Rd, Coimbatore, Tamil Nadu- 641043, India. Electronic address:

Spine J 2022 05;22(5):890-891

Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.

J Clin Anesth 2022 09 28;80:110797. Epub 2022 Apr 28.

Department of Anesthesiology and Reanimation, Çukurova University, Adana, Turkey.

Study Objective: We aimed to test the hypothesis that erector spinae plane block (ESPB) provides efficient analgesia and reduces postoperative morphine consumption in children undergoing cardiac surgery with median sternotomy.

Design: A prospective, blinded, randomized, controlled study.

Setting: A tertiary university hospital, operating room and intensive care unit. Read More

Med Sci Monit 2022 Apr 29;28:e935563. Epub 2022 Apr 29.

Department of General Surgery, Ruijin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China (mainland).

BACKGROUND This study aimed to compare a precision approach to intraoperative nerve block with traditional analgesia to reduce postoperative pain in 120 patients during thyroid surgery. The precision intraoperative technique used 0.3% ropivacaine to block the lower branch of the transverse cervical nerve and the inner branches of the supraclavicular nerve. Read More

J Shoulder Elbow Surg 2022 Apr 23. Epub 2022 Apr 23.

Department of Orthopaedic Surgery, Duke University, Durham, NC, USA. Electronic address:

Background: Multimodal pain regimens in total shoulder arthroplasty (TSA) now include regional anesthetic techniques. Historically, regional anesthesia for extended postoperative pain control in TSA was administered using a continuous interscalene catheter (CIC). Liposomal bupivacaine is used for its potential for similar pain control and fewer complications compared to indwelling catheters. Read More